Self-uncapping type positioning tool for eight-connection pipe for centrifugation

Abstract

The utility model discloses a self-uncapping type positioning tool for eight-connection pipes for centrifugation. Comprising a tool shell, a pipe cap clamping assembly, a main body clamping assembly, a pipe body ejection assembly and an uncapping activation assembly. By adopting the pipe cap clamping assembly and the main body clamping assembly, the pipe cap and the pipe body are locked in a separated mode, on this basis, by means of centrifugal force, the main body clamping assembly clamps the pipe body to slide outwards in the centrifugal process, but the cap body is blocked to the pipe cap clamping assembly, so that the self-separation effect of the pipe and the cap is achieved, and the phenomenon that in the manual direct cap pulling process, the cap is separated from the pipe body is avoided. The technical problem of mutual dyeing caused by splashing in the eight-connection pipe is solved. Meanwhile, by additionally arranging a cap-removing activation assembly, the automatic cap-removing function of the eight-connection pipe of the tool can be controlled in an enabled mode, the requirements of two different states, namely a pipe and cap separation state and a pipe and cap blocking state, are met when two times of centrifugation are finished in standard medical operation, and the use convenience is improved.

Description

Technical Field

[0001] The embodiments of this utility model belong to the field of eight-tube centrifuge technology, and more specifically, relate to a self-removing cap positioning fixture for eight-tube centrifuges. Background Technology

[0002] Centrifugation is a common experimental technique used in biomedicine, chemical analysis, and molecular biology to separate different components in liquids. Eight-tube sets are a common experimental container, and centrifugation is an integral part of their medical procedures. However, traditional eight-tube sets present a significant technical problem during centrifugation: the caps must be manually opened after centrifugation. This process is not only cumbersome but also prone to liquid splashing, causing sample contamination and potentially posing a safety hazard to operators. Therefore, there is an urgent need for new devices or methods to solve the problem of safe and convenient cap opening of eight-tube sets.

[0003] To address the aforementioned issues, several improvements have been proposed and applied in practical experiments. For example, adding an auxiliary opening device, such as a lever-type or button-type opening structure, to the eight-tube connector aims to simplify the opening operation. Furthermore, another improvement involves using an elastic material to make the lid, leveraging the material's elastic properties to achieve automatic lid opening after centrifugation.

[0004] Although the above technical solutions or devices have reduced the difficulty of opening the cap to a certain extent, the following technical problems or directions for improvement still exist: (1) For the method of adding an auxiliary cap opening device, due to its complex structure, it increases the manufacturing cost of the eight-tube connector and the difficulty of use and maintenance, and at the same time, it does not completely avoid the problem of liquid splashing. (2) For the design of the elastic cap, there are limitations in practical applications. For example, the elastic material is prone to aging after long-term use, which leads to a decrease in sealing performance, and may not be able to effectively remove the cap due to insufficient elasticity during high-speed centrifugation. (3) The above solutions cannot completely avoid the problem of liquid splashing. However, if an eight-tube positioning fixture that can automatically separate the cap from the tube body during centrifugation can be considered, it will greatly simplify the operation process, eliminate the hidden danger of liquid splashing, and improve the safety and efficiency of the experiment. Utility Model Content

[0005] To address the aforementioned deficiencies or improvement needs of existing technologies, this utility model provides a self-removing cap-positioning fixture for eight-tube centrifugation. By employing a cap clamping assembly and a main clamping assembly, the cap and tube body are locked together. Furthermore, utilizing centrifugal force, the main clamping assembly slides the tube body outwards during centrifugation, while the cap is blocked by the cap clamping assembly, thus achieving self-separation of the tube and cap. This prevents the technical problem of cross-contamination caused by splashing inside the eight-tube connector during manual cap removal. Simultaneously, by adding a cap-removal activation assembly, the self-removing cap function of the eight-tube connector can be enabled and controlled, meeting the requirement in standard medical operations that the tube and cap should be in two different states at the end of two centrifugations: "tube and cap separated" and "tube and cap closed," respectively. This improves ease of use.

[0006] To achieve the above objectives, a centrifugal eight-tube self-detaching positioning fixture includes:

[0007] The fixture housing includes a cap clamping assembly fixedly installed on the top of the fixture housing, a main clamping assembly vertically slidably installed in the inner cavity of the fixture housing, a tube ejection assembly located below the main clamping assembly and used to eject the eight-tube connector upwards, and a cap removal activation assembly for controlling whether the eight-tube connector separates during centrifugation; the side wall of the fixture housing is provided with a locking hole for convenient centrifuge head positioning.

[0008] The main clamping assembly includes a tube body locking hole aligned with the inner through hole of the tube cap clamping assembly, and a flexible clamping flange located on the inner side wall of the tube body locking hole; the eight-tube connector is inserted into the tube body locking hole and clamped by the flexible clamping flange.

[0009] Preferably, the cap clamping assembly includes:

[0010] A main board layer is fixedly connected to the upper surface of the tooling housing, and a through array of tube insertion holes are opened in the main board layer; a cap snap-fit ​​layer covers the upper surface of the main board layer, and a through array of cap snap-fit ​​holes are opened in the cap snap-fit ​​layer, with the cap snap-fit ​​holes aligned with the tube insertion holes.

[0011] Preferably, the shape of the cap body's locking hole is an arc-shaped hole.

[0012] Preferably, the cap insert layer is made of rubber.

[0013] Preferably, the tube ejection assembly includes:

[0014] The tooling housing includes a pressing opening at the bottom, a mounting groove on the inner bottom surface of the tooling housing, a base plate that slides vertically in the mounting groove, and a pushing block fixed to the upper surface of the pushing plate.

[0015] Preferably, the decapping activation component includes:

[0016] The assembly includes a sloping groove on the side wall of the cap clamping assembly, a horizontal sliding block that slides within the sloping groove, and a threaded rod that is threadedly driven by the horizontal sliding block. The threaded rod extends outward through the tooling housing and has a manual knob at its extended end. A push spring is installed between the bottom of the cap clamping assembly and the bottom surface of the tooling housing.

[0017] Preferably, the tube insertion holes are arranged in 8 columns and 12 rows.

[0018] In summary, compared with the prior art, the above-described technical solution conceived by this utility model can achieve the following beneficial effects:

[0019] This utility model discloses a self-removing cap positioning fixture for eight-tube centrifugation. By employing a cap clamping assembly and a main clamping assembly, it achieves separate locking of the cap and tube body. Based on this, using centrifugal force, the main clamping assembly slides the tube body outwards during centrifugation, while the cap is blocked by the cap clamping assembly, thus achieving self-separation of the tube and cap. This prevents the technical problem of cross-contamination caused by splashing inside the eight-tube connector during manual cap removal. Simultaneously, by adding a cap removal activation assembly, the self-removing cap function of the eight-tube connector can be enabled and controlled, meeting the requirement in standard medical operations that the tube and cap should be in two different states at the end of two centrifugations: "tube and cap separated" and "tube and cap closed," respectively. This improves ease of use. Attached Figure Description

[0020] Figure 1 This is a schematic diagram of the overall structure of an eight-tube self-detaching positioning fixture for centrifugation according to an embodiment of the present invention.

[0021] Figure 2 This is a schematic diagram of the installation state of an eight-tube self-detaching positioning fixture for centrifugal centrifuges according to an embodiment of the present invention.

[0022] Figure 3 This is a schematic diagram of the first centrifugation process of an eight-tube self-detaching positioning fixture for centrifugation according to an embodiment of the present invention.

[0023] Figure 4 This is a schematic diagram of the nucleic acid loading process after centrifugation using an eight-tube self-removing positioning fixture for centrifugation, according to an embodiment of this utility model.

[0024] Figure 5 This is a schematic diagram of the posture during the second centrifugation process of an eight-tube self-detaching positioning fixture for centrifugation according to an embodiment of the present invention.

[0025] In all the accompanying drawings, the same reference numerals denote the same technical features, specifically: 1-tool housing, 101-fixing hole, 102-guide block, 2-cap clamping assembly, 201-tube insertion hole, 210-cap insertion layer, 211-arc-hole, 3-main clamping assembly, 301-tube locking hole, 302-flexible clamping flange, 4-tube ejection assembly, 401-pressing opening, 402-mounting groove, 410-push plate, 411-base plate, 412-push block, 5-cap removal activation assembly, 501-manual knob, 502-threaded rod, 503-translation locking block, 504-sloping locking groove, 505-push spring, 6-eight-tube connector, 601-tube body, 602-cap body, 7-syringe. Detailed Implementation

[0026] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing this utility model and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model.

[0027] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this utility model, "a plurality of" means two or more, unless otherwise explicitly specified.

[0028] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0029] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only for explaining the present utility model and are not intended to limit the present utility model. Furthermore, the technical features involved in the various embodiments of the present utility model described below can be combined with each other as long as they do not conflict with each other.

[0030] like Figures 1-5 As shown in this embodiment of the invention, the centrifugal eight-tube self-detaching positioning fixture includes:

[0031] The fixture housing 1 includes a pipe cap clamping assembly 2 fixedly installed on the top of the fixture housing 1, a main body clamping assembly 3 vertically slidably installed in the inner cavity of the fixture housing 1, a pipe ejection assembly 4 located below the main body clamping assembly 3 and used to push the eight-connected pipe upwards, and a cap removal activation assembly 5 used to control whether the eight-connected pipe separates during the centrifugation process; the side wall of the fixture housing 1 is provided with a locking hole 101 for convenient centrifuge head positioning.

[0032] The main clamping assembly 3 includes a tube body locking hole 301 that is aligned with the inner through hole of the tube cap clamping assembly 2, and a flexible clamping flange 302 located on the inner side wall of the tube body locking hole 301; the eight-tube body 601 is inserted into the tube body locking hole 301 and clamped by the flexible clamping flange 302.

[0033] like Figure 1 As shown in this embodiment of the utility model, the cap clamping assembly 2 includes:

[0034] A main board layer is fixedly connected to the upper surface of the tooling housing 1, and a tube insertion hole 201 is formed in the main board layer through an array; a cap insert layer 210 is covered on the upper surface of the main board layer, and a cap snap hole is formed in the cap insert layer 210 through an array, wherein the cap snap hole is aligned with the tube insertion hole 201.

[0035] like Figure 1 As shown in this embodiment of the utility model, the shape of the cap body card hole is an arc-shaped hole 211.

[0036] like Figure 1 As shown in this embodiment of the utility model, the cap insert layer 210 is made of rubber.

[0037] like Figure 1 As shown in the present invention, the tube ejection assembly 4 includes: a pressing opening 401 at the bottom of the tooling housing 1, a mounting groove 402 on the inner bottom surface of the tooling housing 1, a base plate 411 that slides vertically in the mounting groove 402, and a pushing block 412 fixed to the upper surface of the pushing plate 410.

[0038] like Figures 1-5 As shown, in this embodiment of the present invention, the cap-removing activation component 5 includes:

[0039] The pipe cap clamping assembly 2 has an inclined groove 504 on its side wall, a translation block 503 that slides horizontally within the inclined groove 504, and a threaded rod 502 that is threadedly driven by the translation block 503. The threaded rod 502 extends outward through the tooling housing 1, and a manual knob 501 is provided at the extended end of the threaded rod 502. A push spring 505 is provided between the bottom of the pipe cap clamping assembly 2 and the inner bottom surface of the tooling housing 1.

[0040] In this embodiment of the utility model, the tube insertion holes 201 are arranged in 8 columns and 12 rows.

[0041] Working principle of this utility model embodiment:

[0042] S100: First, using the locking hole 101, the entire utility model is inserted into the centrifuge head. Then, the eight-tube connector is inserted from the tube insertion hole 201 to the tube locking hole 301, and the cap 602 of the eight-tube connector is inserted into the arc-shaped hole 211 to prevent the cap from flying off during centrifugation. Under the action of the flexible clamping flange 302, the main body of the tube 601 is locked into the tube locking hole 301.

[0043] S200: Subsequently, turn the manual knob 501, thereby controlling the translation block 503 to move to the left under the action of the threaded transmission. This moves the translation block 503 away from the inclined groove 504 in the initial state, thereby increasing the downward sliding range of the main clamping assembly 3 and activating the cap-removal property of this invention during the centrifugation process, i.e. Figure 3 As shown, during the centrifugation process, under the action of centrifugal force, the main clamping assembly 3 clamps the tube body 601 and slides outward, while the cap body 602 is blocked by the cap clamping assembly 2, thereby achieving separation of the two.

[0044] It should be noted that in commonly used medical centrifuges, after the centrifugation program is started, the centrifuge head will rotate outward due to centrifugal force in order to carry this invention from... Figure 2 State reached Figure 3 attitude;

[0045] S300: After centrifugation is complete, if... Figure 4 As shown, manually remove the cap and, according to medical operational requirements, inject nucleic acid into the centrifuged eight-tube set. Then, reverse the manual knob 501 to move the translation block 503 to the right. Under the contact action of the inclined groove 504 and the translation block 503, the possibility of the main clamping assembly 3 sliding downwards is eliminated, thus locking the main clamping assembly 3 onto the lower surface of the cap clamping assembly 2. This prevents cap separation during the second centrifugation process. Figure 5 As shown, this meets the standard medical procedure requirement of centrifuging eight tubes and then performing PCR amplification directly with the caps closed.

[0046] S400: After amplification is complete, the substrate 411 can be manually pushed upward through the pressing opening 401, thereby pushing the eight tubes in the tube body card hole 301 upward with the help of the pushing block 412.

[0047] In this embodiment of the invention, a cap clamping assembly and a main clamping assembly are used to lock the cap and tube body separately. Based on this, centrifugal force is used to cause the main clamping assembly 3 to slide the tube body 601 outwards during centrifugation, while the cap body 602 is blocked by the cap clamping assembly 2. This achieves self-separation of the tube and cap, preventing the technical problem of cross-contamination caused by splashing inside the eight-tube connector during manual cap removal. Simultaneously, by adding a cap removal activation assembly 5, the self-cap removal function of the eight-tube connector can be enabled and controlled, meeting the requirement in standard medical operations that the tube and cap should be in two different states at the end of two centrifugations: "tube and cap separated" and "tube and cap closed." This improves ease of use.

[0048] The above are merely preferred embodiments of this application and are not intended to limit this application. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this application should be included within the protection scope of this application. The above are merely preferred embodiments of this application. It should be noted that for those skilled in the art, several improvements and modifications can be made without departing from the technical principles of this application, and these improvements and modifications should also be considered within the protection scope of this application.

Claims

1. A self-decapping positioning tool for eight-connection tubes for centrifugation, characterized by, include: The tooling housing (1), the cap clamping assembly (2) fixedly installed on the top of the tooling housing (1), the main body clamping assembly (3) vertically slidably installed in the inner cavity of the tooling housing (1), the tube ejection assembly (4) located below the main body clamping assembly (3) and used to push the eight-tube connector upwards, and the cap removal activation assembly (5) used to control whether the eight-tube connector separates during the centrifugation process; the side wall of the tooling housing (1) is provided with a locking hole (101) for convenient centrifuge head positioning; The main clamping assembly (3) includes a tube body locking hole (301) aligned with the inner through hole of the tube cap clamping assembly (2) and a flexible clamping flange (302) provided on the inner side wall of the tube body locking hole (301); the eight-tube tube body (601) is inserted into the tube body locking hole (301) and clamped by the flexible clamping flange (302).

2. The centrifugal eight-tube self-detaching positioning fixture according to claim 1, characterized in that, The cap clamping assembly (2) includes: A main board layer is fixedly connected to the upper surface of the tooling housing (1), and a tube insertion hole (201) is opened in the main board layer through an array; a cap snap-in layer (210) is covered on the upper surface of the main board layer, and a cap snap-in hole is opened in the cap snap-in layer (210) through an array, wherein the cap snap-in hole is aligned with the tube insertion hole (201).

3. The centrifugal eight-tube self-detaching positioning fixture according to claim 2, characterized in that, The shape of the cap body's locking hole is an arc-shaped hole (211).

4. A centrifugal eight-tube self-detaching positioning fixture according to claim 2, characterized in that, The cap insert (210) is made of rubber.

5. A centrifugal eight-tube self-detaching positioning fixture according to claim 3, characterized in that, The tube ejection assembly (4) includes: A pressing opening (401) is provided at the bottom of the tooling housing (1), a mounting groove (402) is provided on the inner bottom surface of the tooling housing (1), a base plate (411) that slides vertically in the mounting groove (402), a push plate (410), and a push block (412) fixed to the upper surface of the push plate (410).

6. A centrifugal eight-tube self-detaching positioning fixture according to claim 1, characterized in that, The decapping activation component (5) includes: An inclined groove (504) is provided on the side wall of the cap clamping assembly (2), a translation block (503) is kept horizontally sliding in the inclined groove (504), and a threaded rod (502) is threadedly driven by the translation block (503); the threaded rod (502) extends outward through the tooling housing (1), and a manual knob (501) is provided at the extended end of the threaded rod (502); a push spring (505) is provided between the bottom of the cap clamping assembly (2) and the inner bottom surface of the tooling housing (1).

7. A centrifugal eight-tube self-detaching positioning fixture according to claim 2, characterized in that: The tube insertion holes (201) are arranged in 8 columns and 12 rows.

Images