Portable medical low-temperature box

By introducing a refrigeration chamber and delivery pipe system into a portable medical cryo-chamber, the problems of single cold source and increased equipment weight are solved, enabling multiple cold source options and improving portability, while ensuring the stability and safety of cryogenic preservation.

CN224257388UActive Publication Date: 2026-05-19FOSUN ADGENVAX BIOTECHONOLOGY CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
FOSUN ADGENVAX BIOTECHONOLOGY CO LTD
Filing Date
2025-04-23
Publication Date
2026-05-19

AI Technical Summary

Technical Problem

Existing portable medical cryogenic chambers have limited versatility, typically only supporting one or two cold sources, and real-time cooling requires additional equipment, increasing weight and affecting portability.

Method used

A portable medical cryogenic chamber was designed, comprising a refrigerated inner chamber and a switchable delivery tube. Different refrigerants are introduced through the delivery tube, and the pressure is regulated by a pressure relief valve to enable the use of multiple cold sources. The insulated inner chamber and flame-retardant materials improve the sealing and portability.

Benefits of technology

It enables the selection of different cold sources for cryogenic preservation as needed, reduces the need to carry additional equipment, improves portability and applicability, and ensures the stability and safety of cryogenically preserved items.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses a portable medical low-temperature box, which belongs to the technical field of medical low-temperature boxes, and is provided with a refrigeration inner box, the side wall and the bottom plate of the refrigeration inner box are of hollow structures, the refrigeration inner box forms a continuous cavity through the side wall and the hollow part of the bottom plate, and the refrigeration inner box is communicated with the outside through a delivery pipe capable of being opened and closed. During use, different fluid media for refrigeration can be selected according to the temperature requirement of stored articles, then the conveying pipe is opened, the fluid media are input into the cavity through the conveying pipe, and the conveying pipe is closed after conveying is completed; the low-temperature storage device can contain different fluid media for refrigeration so as to achieve the technical effect of transferring low-temperature storage articles with different temperature requirements.
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Description

Technical Field

[0001] This utility model belongs to the field of medical low-temperature chamber technology, specifically relating to a portable medical low-temperature chamber. Background Technology

[0002] In the biomedical field, biologically active substances (such as monoclonal antibodies, recombinant protein vaccines, and nucleic acid vaccines) typically require low-temperature conditions during storage or transportation to prevent denaturation and inactivation. Medical cryo-boxes, also known as biomedical freezers or medical cryopreservation boxes, are devices specifically designed for the preservation of biological samples, pharmaceuticals, vaccines, and other items requiring cryopreservation. They ensure the activity and stability of stored items through a low-temperature environment.

[0003] Portable medical cryo-boxes are mainly used for the temporary transport of small quantities of items requiring cryopreservation to ensure their activity and stability as much as possible. However, existing portable medical cryo-boxes have the following drawbacks:

[0004] 1. The cold source is usually switched between ice, dry ice or other substances to meet the temperature requirements of sensitive sample storage. However, a single-structure medical low temperature box often only corresponds to one or two cold sources, which has low versatility. For example, ice is usually filled in ice boxes, but the ice boxes do not have reserved holes. After filling with cold sources with extremely low boiling points such as liquid carbon dioxide or liquid nitrogen, the evaporation of the cold source may cause the internal pressure of the ice box to increase sharply, until the box explodes.

[0005] 2. Real-time cooling methods such as compressor refrigeration require carrying additional items besides the insulated box itself, such as power supply and refrigeration equipment, which increases the weight of the insulated box and greatly reduces its portability. Utility Model Content

[0006] In view of the above-mentioned problems mentioned in the background art, the present invention provides a portable medical low-temperature box to solve the problem that single-structure medical low-temperature boxes often only correspond to one or two cold sources and thus have low versatility, as well as the problem that real-time cooling requires carrying additional items in addition to the insulated box itself, which increases the weight of the insulated box and thus greatly reduces its portability.

[0007] To achieve the above objectives, this utility model provides the following technical solution:

[0008] A portable medical cryoprotector includes a main body, one side of which is hinged to a main cover, and further includes:

[0009] Refrigeration inner box; The refrigeration inner box is a box without a top. The side walls and bottom plate of the refrigeration inner box are hollow structures. The refrigeration inner box forms a continuous cavity through the hollow parts of the side walls and bottom plate. The cavity is filled with a refrigeration fluid medium. The refrigeration inner box is fixedly installed in the main box.

[0010] At least one switchable delivery pipe; the first end of the delivery pipe is connected to the side wall of the refrigeration inner box, the second end of the delivery pipe passes through the main box and is connected to the outside, and the second end of the delivery pipe is equipped with a pressure relief valve;

[0011] Container placement seat; the container placement seat is fixedly installed in the refrigeration inner box, and the container placement seat is used to place and fix the container containing the medicine / reagent that needs to be stored at low temperature.

[0012] Preferably, the medical low-temperature chamber also includes an insulated inner chamber, which is made of insulation material and is a topless chamber. The insulated inner chamber is fixedly installed in the main chamber, and the refrigeration inner chamber is fixedly installed in the insulated inner chamber. The second end of the delivery pipe passes through the insulated inner chamber and the main chamber in sequence and then connects to the outside.

[0013] Preferably, limit blocks are fixedly connected around the top of the main housing, and limit grooves are opened on the bottom surface of the main housing cover at positions corresponding to the limit blocks. When the main housing cover is fastened to the main housing cover, the limit blocks and limit grooves are engaged.

[0014] Preferably, a latch is provided on the first side of the main body, and a locking block is fixedly provided on the first side of the main cover at a position corresponding to the latch.

[0015] Preferably, polyurethane foam is used as the insulation material for the inner insulated box.

[0016] Preferably, the container placement base is a sponge block, and the top surface of the container placement base is provided with multiple placement blind holes. The diameter of the placement blind holes is smaller than the diameter of the container. When a container is inserted into a placement blind hole, the outer wall of the container is pressed and contacted with the inner wall of the placement blind hole.

[0017] Preferably, the main body and the main cover are made of XPS extruded polystyrene impregnated with flame retardant.

[0018] Preferably, the top surface of the main box lid is provided with a handle.

[0019] Compared with the prior art, the beneficial effects of this utility model are:

[0020] This application includes a refrigeration inner chamber with hollow side walls and a hollow bottom plate. The refrigeration inner chamber forms a continuous cavity through the hollow portions of the side walls and bottom plate, and is connected to the outside through a switchable delivery pipe. In use, different refrigeration fluid media can be selected according to the temperature requirements of the items to be stored. The delivery pipe is then opened to input the fluid media into the cavity. After delivery, the delivery pipe is closed. During the transfer process, the pressure relief valve can adjust the pressure inside the cavity in real time. This application can accommodate different types of refrigeration fluid media to achieve the technical effect of transferring low-temperature stored items with different temperature requirements. Attached Figure Description

[0021] Figure 1 This is a schematic diagram of the structure of this application;

[0022] Figure 2 This is a schematic diagram showing the positions of the delivery pipe and the pressure relief valve;

[0023] Figure 3 This is a schematic diagram of the structure of the delivery pipe and the refrigeration inner box;

[0024] The diagram is marked as follows:

[0025] 1-Main box; 2-Limit block; 3-Insulated inner box; 4-Refrigerated inner box; 5-Locking block; 6-Main box cover; 7-Container placement seat; 8-Lock; 9-Screw cap; 10-Conveying pipe; 11-Pressure relief valve. Detailed Implementation

[0026] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0027] Example 1

[0028] like Figure 1 , Figure 2 and Figure 3 As shown, a portable medical cryogenic chamber includes a main body 1, with a main cover 6 hinged to one side of the main body 1, and also includes:

[0029] Refrigeration inner box 4; Refrigeration inner box 4 is a box without a top. The side walls and bottom plate of refrigeration inner box 4 are hollow structures. Refrigeration inner box 4 forms a continuous cavity through the hollow parts of the side walls and bottom plate. The cavity is filled with a refrigeration fluid medium. Refrigeration inner box 4 is fixedly installed in the main box 1.

[0030] Two switchable delivery pipes 10; the first end of the delivery pipe 10 is connected to the side wall of the inner refrigeration box 4, and the second end of the delivery pipe 10 passes through the main box 1 and is connected to the outside. Each delivery pipe 10 has a thread on its second end and is threaded to the cap 9. One of the delivery pipes 10 has a pressure relief valve 11 on its second end.

[0031] Container placement seat 7; Container placement seat 7 is fixedly installed in the refrigeration inner box 4, and the container is placed in container placement seat 7.

[0032] When using this application, different refrigeration fluid media can be selected according to the temperature requirements of the preserved items. Then, the delivery pipe 10 is opened, and the fluid media is input into the cavity through the delivery pipe 10. After the delivery is completed, the delivery pipe 10 is closed. During the transfer task performed by this application, the pressure relief valve 11 can adjust the pressure in the cavity in real time. This application can accommodate different refrigeration fluid media to achieve the technical effect of transferring low-temperature preserved items with different temperature requirements. For example, when transporting vaccines, medicines, and blood products, an ice-water mixture can be selected as the refrigeration fluid media. When transporting sensitive samples such as viruses, live cells, and genetic materials, refrigerants such as R-404A, trifluoromethane, and liquid nitrogen assisted refrigerants can be selected.

[0033] Example 2

[0034] The difference between this embodiment and Embodiment 1 is that, as Figure 1 As shown, the medical low-temperature chamber also includes an insulated inner box 3, which is made of insulation material and is a topless box. The insulated inner box 3 is fixedly installed in the main box 1, and the refrigeration inner box 4 is fixedly installed in the insulated inner box 3. The second end of the delivery pipe 10 passes through the insulated inner box 3 and the main box 1 in sequence and then communicates with the outside.

[0035] In this embodiment, the insulated inner box 3 can further prevent the heat exchange between the refrigeration inner box 4 and the outside, so that the temperature inside the main box 1 remains stable.

[0036] Example 3

[0037] The difference between this embodiment and Embodiment 1 is that, as Figure 1 As shown, limit blocks 2 are fixedly connected around the top of the main housing 1. Limit grooves are formed on the bottom surface of the main housing cover 6 at positions corresponding to the limit blocks 2. Sealing gaskets are provided in the limit grooves. Two latches 8 are provided on the first side of the main housing 1. Locking blocks 5 are fixedly provided at two positions on the first side of the main housing cover 6 corresponding to the two latches 8. The main housing cover 6 is fastened to the main housing 1. The limit blocks 2 are engaged with the limit grooves. When the latches 8 and locking blocks 5 are locked one by one, the sealing gaskets simultaneously press against the limit blocks 2 and the bottom of the limit grooves. This structure can enhance the sealing performance of this application and prevent external pollution sources from entering the main housing 1.

[0038] Example 4

[0039] The difference between this embodiment and embodiment 2 is that the insulation material of the inner insulation box 3 is polyurethane foam. The thermal conductivity of rigid polyurethane foam is only 0.018-0.024 W / (m·k), which is about half that of traditional insulation materials such as EPS. It can significantly reduce heat transfer. In addition, the closed-cell rate of polyurethane foam is as high as 90% or more, which can effectively isolate air convection and moisture penetration, and maintain stable insulation performance for a long time.

[0040] Example 5

[0041] The difference between this embodiment and Embodiment 1 is that, as Figure 1 As shown, the container placement seat 7 is a sponge block. The top surface of the container placement seat 7 is provided with multiple placement blind holes. The diameter of the placement blind holes is smaller than the diameter of the container. When a container is inserted into a placement blind hole, the outer wall of the container is pressed and contacted with the inner wall of the placement blind hole.

[0042] In this embodiment, the sponge block has good elasticity and can deform to absorb kinetic energy after being impacted, so as to prevent the container from being damaged by the impact.

[0043] Example 6

[0044] The difference between this embodiment and Embodiment 1 is that the main housing 1 and the main housing cover 6 are both made of XPS extruded polystyrene impregnated with flame retardant. XPS extruded polystyrene has a thermal conductivity of 0.030-0.035 W / (m·K), a compressive strength of 150-700 kPa, and does not absorb water, making it suitable for medical applications that require frequent handling. Although the fire rating of XPS extruded polystyrene is only B1, it can meet the medical device specifications after adding flame retardant.

[0045] Example 7

[0046] The difference between this embodiment and embodiment 1 is that the top surface of the main box cover 6 is provided with a handle, which allows the operator to lift the application, improving the convenience of transportation and carrying.

Claims

1. A portable medical cryogenic chamber, comprising a main chamber body (1), wherein a main chamber cover (6) is hinged to one side of the main chamber body (1), characterized in that, Medical cryogenic chambers also include: Refrigeration inner box (4); The refrigeration inner box (4) is a box without a top. The side walls and bottom plate of the refrigeration inner box (4) are hollow structures. The refrigeration inner box (4) forms a continuous cavity through the hollow parts of the side walls and bottom plate. The cavity is filled with a refrigeration fluid medium. The refrigeration inner box (4) is fixedly installed in the main box (1). At least one switchable delivery pipe (10); the first end of the delivery pipe (10) is connected to the side wall of the refrigeration inner box (4), the second end of the delivery pipe (10) passes through the main box (1) and is connected to the outside, and the second end of the delivery pipe (10) is provided with a pressure relief valve (11). Container placement seat (7); The container placement seat (7) is fixedly installed in the refrigeration inner box (4).

2. The portable medical cryobox according to claim 1, characterized in that, The medical low-temperature box also includes an insulated inner box (3), which is made of insulation material. The insulated inner box (3) is a box without a top. The insulated inner box (3) is fixedly installed in the main box (1). The refrigeration inner box (4) is fixedly installed in the insulated inner box (3). The second end of the delivery pipe (10) passes through the insulated inner box (3) and the main box (1) in sequence and then communicates with the outside.

3. A portable medical cryoprotector according to claim 2, characterized in that, The insulation material for the inner insulated box (3) is polyurethane foam.

4. A portable medical cryoprotector according to claim 1, characterized in that, Limiting blocks (2) are fixedly connected around the top of the main box (1). A limiting groove is opened on the bottom surface of the main box cover (6) at the position corresponding to the limiting block (2). When the main box cover (6) is fastened to the main box (1), the limiting block (2) is engaged with the limiting groove.

5. A portable medical cryoprotector according to claim 1, characterized in that, A latch (8) is provided on the first side of the main box (1), and a locking block (5) is fixedly provided on the first side of the main box cover (6) at the position corresponding to the latch (8).

6. A portable medical cryobox according to claim 1, characterized in that, The container placement seat (7) is a sponge block. The top surface of the container placement seat (7) is provided with multiple blind holes. The diameter of the blind holes is smaller than the diameter of the container. When a container is inserted into a blind hole, the outer wall of the container is pressed against the inner wall of the blind hole.

7. A portable medical cryoprotector according to claim 1, characterized in that, The top surface of the main box cover (6) is provided with a handle.