Traditional Chinese medicine patch for oral mucositis

By designing a dressing medium made of honey and a dressing containing nano-extracted Phellodendron bark charcoal and alum, the problem of rapid drug dissolution in oral mucositis has been solved, the dressing time has been extended, the tightness and efficiency of treatment have been improved, and the treatment plan can be adjusted according to the size of the oral mucositis, reducing the risk of bacterial growth and improving the treatment effect.

CN224307590UActive Publication Date: 2026-06-02GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
GUANGANMEN HOSPITAL CHINA ACAD OF CHINESE MEDICAL SCI
Filing Date
2025-04-29
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing oral mucositis dressings have rapid drug dissolution inside the mouth, resulting in a shorter dressing duration and making them ineffective in treating oral mucositis, thus affecting patients' quality of life and treatment progress.

Method used

A traditional Chinese medicine patch for oral mucositis was designed, using a patch medium prepared with honey and nano-extracted Phellodendron bark charcoal and alum traditional Chinese medicine components. The patch's adhesion is improved through a trapezoidal structure and a bonding reinforcement structure. An external pH colorimetric layer is installed to detect oral pH and control the volatilization rate of the traditional Chinese medicine components and the therapeutic effect.

Benefits of technology

It extends the application time, improves the tightness and efficiency of treatment, allows for adjustment of the application medium according to the size of oral mucositis, timely adjustment of the treatment plan, reduces the risk of bacterial growth, and improves the treatment effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to traditional Chinese medicine plaster technical field, and disclose a kind of traditional Chinese medicine plaster for oral mucosa inflammation, including plaster medium, the lower end of plaster medium is adhesively installed with traditional Chinese medicine component, and it is installed between plaster medium and traditional Chinese medicine component with the structure of fit reinforcement, the structure of fit reinforcement drives between plaster medium and traditional Chinese medicine component and carries out adhesion fixation, and the four edges outside plaster medium are respectively adhesively installed with outer auxiliary adhesive layer.The traditional Chinese medicine plaster for oral mucosa inflammation, through the lower part of plaster medium is installed with traditional Chinese medicine component, while plaster medium drives traditional Chinese medicine component to be applied in oral mucosa inflammation place, while plaster medium and traditional Chinese medicine component are trapezoidal, improve the compactness when equipment is applied, and use with cortex phellodendri and white alum, first, pay attention to supplement its deficiency, first, pay attention to close its sore surface, both are used to solve its toxic heat, while plaster medium takes slow-release material, not with oral mucosa direct contact deep layer takes slow-release material, prolongs analgesic duration.
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Description

Technical Field

[0001] This utility model relates to the field of traditional Chinese medicine plaster technology, specifically a traditional Chinese medicine plaster for oral mucositis. Background Technology

[0002] Oral mucositis refers to inflammatory and / or ulcerative lesions of the oral mucosa. Common causes or triggers include pathogenic microorganisms, immune dysfunction, physical and chemical damage, and certain medications. For patients with malignant tumors, the use of treatments such as radiotherapy, chemotherapy, molecular targeted therapy, and immune checkpoint inhibitors are the main causes of oral mucositis (OM).

[0003] However, oral mucosal inflammation (OM) not only includes objective signs such as erythema, edema, congestion, erosion, and ulceration of the oral mucosa, but also subjective symptoms such as local pain, difficulty eating, and taste disturbance. This reduces the quality of life of cancer patients, their adherence to and tolerance of anti-tumor treatment, and may even delay or terminate the treatment process, affecting the long-term survival of patients. Furthermore, since the mucosal inflammation is located inside the oral cavity, when the medicine is applied externally to the mucosal inflammation, it will dissolve rapidly upon contact with the oral cavity, resulting in a decrease in the duration of application and failure to achieve the desired therapeutic effect on the mucosal inflammation. Therefore, we propose a traditional Chinese medicine poultice for oral mucosal inflammation. Utility Model Content

[0004] To address the shortcomings of existing herbal poultices for oral mucositis, this invention provides a herbal poultice for oral mucositis. The poultice contains herbal ingredients attached to the lower end of a dressing medium. These ingredients adhere to the outside of the oral mucosa, while the dressing medium defines the position of the herbal ingredients and covers the wound. The poultice treats the wound through the herbal ingredients. The dressing medium also reduces the overall evaporation rate of the herbal ingredients, increasing the duration of use, thus solving the problems mentioned in the background art.

[0005] This utility model provides the following technical solution: a traditional Chinese medicine dressing for oral mucositis, comprising a dressing medium, wherein a traditional Chinese medicine component is bonded to the lower end of the dressing medium, and a bonding and reinforcing structure is installed between the dressing medium and the traditional Chinese medicine component. The bonding and reinforcing structure drives the dressing medium and the traditional Chinese medicine component to bond and fix each other, and an external auxiliary adhesive layer is bonded to the four sides of the dressing medium.

[0006] Preferably, the bonding and reinforcing structure includes a support pin and an installation groove, the lower part of the dressing medium is fixedly connected to a tapered support pin, and the interior of the traditional Chinese medicine component is provided with an installation groove that matches the support pin.

[0007] Preferably, the dressing medium is prepared using honey, and the traditional Chinese medicine ingredients are applied to the outside of the oral mucosa.

[0008] Preferably, the materials of the traditional Chinese medicine ingredients are charred phellodendron bark and calcined alum, wherein the charred phellodendron bark and calcined alum are prepared using nano-extraction technology.

[0009] Preferably, the dressing medium and the traditional Chinese medicine ingredients are in a trapezoidal structure, with the traditional Chinese medicine ingredients located at the lower end of the dressing medium.

[0010] Preferably, two sets of the external auxiliary adhesive layers are installed on the outside of both the dressing medium and the traditional Chinese medicine ingredients, and a splicing layer is installed between adjacent sets of external auxiliary adhesive layers for fixation.

[0011] Preferably, the splicing layer has a splitting groove inside, and the splitting groove is S-shaped.

[0012] Preferably, a pH color-developing layer is installed on the outside of the dressing medium, wherein the pH color-developing layer is disposed on the inside of the outer auxiliary adhesive layer.

[0013] Compared with existing Chinese medicine poultices, this invention has the following beneficial effects:

[0014] 1. This oral mucositis treatment uses a traditional Chinese medicine patch. The patch contains traditional Chinese medicine ingredients at the bottom, which are then applied to the affected area. The patch and the medicine ingredients are arranged in a trapezoidal shape to improve the tightness of the application. The patch uses a combination of Phellodendron bark and alum to replenish Yin deficiency and astringe the surface of the sores. The combination also helps to clear away the accumulated heat and toxins. Furthermore, the patch uses a slow-release material, which is applied to the deeper layers of the oral mucosa without direct contact, thus prolonging the duration of pain relief.

[0015] 2. This oral mucositis treatment uses traditional Chinese medicine plasters. An external auxiliary adhesive layer is installed on the outside of the plaster medium. At the same time, the external auxiliary adhesive layer drives multiple sets of plaster mediums to form a whole. The size of the plaster medium is selected according to the size of the oral mucositis, and the plaster medium is controlled to adhere to the outside of oral mucositis of different sizes, thereby improving the efficiency of the application.

[0016] 3. This oral mucositis treatment uses traditional Chinese medicine poultices. After the poultice medium and traditional Chinese medicine ingredients are applied to the oral mucositis wound, the pH color-changing layer reinforces the overall structure of the poultice medium and traditional Chinese medicine ingredients. During oral treatment, the pH color-changing layer can be observed to detect changes in oral pH. Based on the oral pH, problems in the oral cavity can be treated in a timely manner, reducing the risk of oral bacterial growth due to changes in pH, which could worsen the damage to the oral mucositis and thus improve the treatment effect. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the main structure of the present utility model;

[0018] Figure 2This is a top view of the structure of this utility model;

[0019] Figure 3 This is a schematic cross-sectional view of the main body of this utility model;

[0020] Figure 4 This is a magnified schematic diagram of the application area of ​​this utility model;

[0021] Figure 5 This utility model Figure 1 Enlarged structural diagram at point A in the middle.

[0022] In the diagram: 1. Adhesive medium; 2. Herbal ingredients; 3. Support pin; 4. Mounting groove; 5. External auxiliary adhesive layer; 6. Splicing layer; 7. Splitting groove. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] Please see Figure 1 , Figure 2 , Figure 3 , Figure 4 and Figure 5 A traditional Chinese medicine patch for oral mucositis includes a patching medium 1, with a traditional Chinese medicine ingredient 2 bonded to the lower end of the patching medium 1. The patching medium 1 and the traditional Chinese medicine ingredient 2 are characterized by an adhesive reinforcement structure installed between them, which drives the patching medium 1 and the traditional Chinese medicine ingredient 2 to adhere and fix them together. An external auxiliary adhesive layer 5 is bonded to the four sides of the patching medium 1.

[0025] Please see Figure 4 The bonding and reinforcing structure includes a support pin 3 and an installation groove 4. The lower part of the application medium 1 is fixedly connected to a conical support pin 3. The interior of the Chinese medicine component 2 is provided with an installation groove 4 that matches the support pin 3. By fixing the support pin 3 to the lower part of the application medium 1 and installing the Chinese medicine component 2 at the lower end of the application medium 1, the installation groove 4 and the support pin 3 are mutually fixed to each other, ensuring that the application medium 1 and the Chinese medicine component 2 are tightly bonded and fixed, and avoiding delamination when the application medium 1 pulls the Chinese medicine component 2 to adhere to the outside of the oral mucosa, which would affect the application effect.

[0026] Please see Figure 3The dressing medium 1 is prepared with honey, and the traditional Chinese medicine ingredient 2 is applied to the outside of the oral mucosa. By using honey or other biomaterials with high adhesion, slow release, low irritation, and strong penetration, the dressing medium 1 can control the adhesion of the traditional Chinese medicine ingredient 2 to the oral mucosa, thereby improving the tightness of the adhesion. At the same time, the dressing medium 1 can carry the traditional Chinese medicine ingredient 2 to continuously treat the wound, and the dressing medium 1 can prevent the traditional Chinese medicine ingredient 2 from spreading too quickly, thereby increasing the duration of application.

[0027] Please see Figure 3 The materials of the Chinese medicine component 2 are charred phellodendron bark and calcined alum. The charred phellodendron bark and calcined alum are prepared using nano-extraction technology. By using nano-extraction technology to prepare charred phellodendron bark and calcined alum, the dilution effect of charred phellodendron bark and calcined alum is improved. At the same time, charred phellodendron bark and calcined alum are used to nourish yin deficiency and astringe the surface of sores, respectively. The combination of the two, along with the detoxification of the accumulated heat and toxins, can then treat oral mucositis.

[0028] Please see Figure 3 The dressing medium 1 and the traditional Chinese medicine component 2 are in a trapezoidal structure, with the traditional Chinese medicine component 2 located at the lower end of the dressing medium 1. The dressing medium 1 and the traditional Chinese medicine component 2 are prepared by adopting a trapezoidal structure. When the dressing medium 1 carries the traditional Chinese medicine component 2 to adhere to the oral mucosa inflammation site, the dressing medium 1 extends to the outside of the traditional Chinese medicine component 2. At the same time, the dressing medium 1 adheres to the outside of the oral mucosa inflammation wound, ensuring that the dressing medium 1 maintains tightness when it is adhered to the outside of the oral mucosa inflammation.

[0029] Please see Figure 1 Two sets of external auxiliary adhesive layers 5 are installed on the outside of both the dressing medium 1 and the traditional Chinese medicine ingredient 2. A splicing layer 6 is installed between adjacent sets of external auxiliary adhesive layers 5 for fixation. Since the external auxiliary adhesive layers 5 are installed on the outside of the dressing medium 1, and the splicing layer 6 is installed between adjacent external auxiliary adhesive layers 5, the splicing layer 6 at the corresponding part is torn apart according to the size of the wound. That is, multiple dressing media 1 can be combined into a whole, and according to the different wounds, it can be driven to adhere to the wound, avoiding the phenomenon that the wound is too large and cannot be adhered. The external auxiliary adhesive layers 5 installed on the outside of the dressing medium 1 can be removed to ensure that the outside of multiple dressing media 1 after being combined into a whole is trapezoidal, providing tightness when adhering.

[0030] Please see Figure 5 The splicing layer 6 has a splitting groove 7 inside, which is S-shaped. The splitting groove 7 inside the splicing layer 6 improves the ease of tearing the splicing layer 6.

[0031] Please see Figure 1A pH color-developing layer is installed on the outside of the dressing medium 1, which is located inside the adhesive layer 5. By installing a pH color-developing layer on the outside of the dressing medium 1, and after the dressing medium 1 and the traditional Chinese medicine ingredient 2 are applied to the oral mucosal inflammation wound, the pH color-developing layer is specifically phenol red or a mixed indicator. The pH color-developing layer reinforces the overall structure of the dressing medium 1 and the traditional Chinese medicine ingredient 2. During oral treatment, the pH level can be detected by observing the color change of the pH color-developing layer. During oral treatment, due to the bacteria in the oral cavity, a large number of bacteria will multiply, and the pH level of the oral cavity will change. By timely observing the pH level of the oral cavity, the control device can treat the oral cavity in a timely manner, reduce the pH level of the oral cavity, and improve the treatment effect.

[0032] Working principle: During use, the Chinese medicine ingredient 2 adheres to the lower end of the dressing medium 1. At the same time, an external auxiliary adhesive layer 5 is installed around the outside of the dressing medium 1. The external auxiliary adhesive layer 5 is fixed by adhesive to ensure that the external auxiliary adhesive layer 5 remains tight when it is attached to the outside of the dressing medium 1. Meanwhile, another set of dressing medium 1 is installed on the outside of the external auxiliary adhesive layer 5 through the splicing layer 6. According to the different sizes of oral mucosal inflammation wounds, the corresponding splitting grooves 7 are torn open, and the corresponding dressing medium 1 is controlled to form a whole, improving the convenience of applying the dressing medium 1.

[0033] While targeted therapy drugs kill tumor cells, they may also damage normal cells in the oral mucosa, disrupting the oral mucosal barrier function. Bacteria, viruses, and other microorganisms in the mouth can then easily multiply, with some bacteria decomposing food debris and producing acidic metabolic products, leading to a decrease in the pH level of the oral environment. Patients may experience decreased appetite and reduced water intake during targeted therapy, resulting in a corresponding decrease in saliva production. Saliva plays a role in buffering acids and alkalis and cleaning the mouth; reduced saliva weakens the mouth's self-cleaning and pH regulation abilities, further contributing to a more acidic oral environment. The treatment involves a pH-developing layer attached to the outside of the dressing medium 1. During the treatment of oral wounds using the dressing medium 1 and the herbal ingredients 2, the pH-developing layer, positioned outside the dressing medium 1, provides a visual indicator of treatment effectiveness by observing its color changes. If the pH-developing layer indicates that the acidity or alkalinity is gradually approaching the normal range, it indicates that the treatment is effective and the condition is gradually improving. Conversely, if it is ineffective, it suggests that further optimization of the treatment plan may be needed, such as changing medications, adjusting dosage or frequency, etc., to improve the targetedness and effectiveness of the treatment. Simultaneously, if the color of the dressing indicates that the acidity or alkalinity is still approaching acidity, it can guide the patient to use alkaline mouthwash to adjust the oral pH, creating a more favorable environment for oral ulcer healing, thereby further improving the treatment effect and preventing bacterial growth during the treatment of oral mucositis, which could lead to pH changes and make the oral cavity difficult to treat.

[0034] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A traditional Chinese medicine poultice for oral mucositis, comprising a poultice medium (1), wherein a traditional Chinese medicine ingredient (2) is adhered to the lower end of the poultice medium (1), characterized in that: An adhesive reinforcement structure is installed between the dressing medium (1) and the traditional Chinese medicine ingredient (2). The adhesive reinforcement structure drives the dressing medium (1) and the traditional Chinese medicine ingredient (2) to be bonded and fixed. An external auxiliary adhesive layer (5) is bonded and installed on the four sides of the dressing medium (1).

2. The traditional Chinese medicine poultice for oral mucositis according to claim 1, characterized in that: The bonding and reinforcement structure includes a support pin (3) and an installation groove (4). The lower part of the application medium (1) is fixedly connected to a tapered support pin (3), and the interior of the Chinese medicine component (2) is provided with an installation groove (4) that matches the support pin (3).

3. The traditional Chinese medicine poultice for oral mucositis according to claim 1, characterized in that: The dressing medium (1) is prepared using honey, and the traditional Chinese medicine ingredients (2) are applied to the outside of the oral mucosa.

4. The traditional Chinese medicine poultice for oral mucositis according to claim 1, characterized in that: The dressing medium (1) and the traditional Chinese medicine ingredient (2) are in a trapezoidal structure, with the traditional Chinese medicine ingredient (2) located at the lower end of the dressing medium (1).

5. A traditional Chinese medicine poultice for oral mucositis according to claim 1, characterized in that: The external auxiliary adhesive layer (5) is installed in two sets on the outside of the application medium (1) and the Chinese medicine ingredients (2), and a splicing layer (6) is installed between the two adjacent sets of external auxiliary adhesive layers (5) for fixing.

6. A traditional Chinese medicine poultice for oral mucositis according to claim 5, characterized in that: The splicing layer (6) has a splitting groove (7) inside, and the splitting groove (7) is S-shaped.

7. A traditional Chinese medicine poultice for oral mucositis according to claim 1, characterized in that: A pH color-developing layer is installed on the outside of the dressing medium (1), wherein the pH color-developing layer is disposed on the inside of the outer auxiliary adhesive layer (5).