A neuronal cell culture medium transport device

Abstract

The utility model discloses a neuron cell culture medium transportation device, including the protection shell of setting up the stand, the equidistance of stand is arranged with the ball block, still include the bearing frame of setting up the perforation, the push plate of the arc surface of ball block resistance cooperation is movably arranged in the perforation, the bottom plate of assembling elastic part is movably arranged on the bearing frame. The utility model provides a neuron cell culture medium transportation device, by placing the culture bottle on the bottom plate makes the elastic piece deformation because of gravity, the culture bottle will move the gravity center to the culture bottle under the bearing frame under this time, make the bearing frame and the bottom plate provide stable location to the culture bottle, and the gravity center can make the perforation position more easily move above the ball block, when the stand inclines with the protection shell, the bearing frame can keep vertical or close to vertical under the action of gravity, compared with traditional follow the inclination, can provide better anti -tilting function to the culture bottle, make the culture solution in the culture bottle produce less bubble by the shaking.

Description

Technical Field

[0001] This utility model relates to the field of cell culture medium transportation technology, and more specifically to a device for transporting culture medium for neuronal cells. Background Technology

[0002] Neuronal cells are typically cultured in culture flasks, and the sealing function of these flasks allows them to be transferred to other departments for storage or use. Mobile carts are used for transportation during the process.

[0003] According to the publication (announcement) number: CN220949843U, the publication (announcement) date: 2024-05-14, a cell culture medium transport device is disclosed, including a mobile trolley and an insulated box installed on the trolley, and a placement box for loading culture medium is installed in the insulated box.

[0004] In the prior art, including the aforementioned patent, the transport trolley inevitably needs to climb slopes during transportation. The culture bottles placed on the trolley will also tilt and shake due to the tilting and shaking. Although the culture bottles will be transferred after the culture is completed, the tilting and shaking will also generate some air bubbles in the bottles. The random dispersion of the air bubbles will cause the cells in the culture medium to be compressed and change position, affecting the normal growth of the cells, or even damaging the cells, resulting in precipitation and stratification. Utility Model Content

[0005] The purpose of this invention is to provide a transport device for culture medium for neuronal cells, aiming to solve the problems mentioned above.

[0006] To achieve the above objectives, this utility model provides the following technical solution:

[0007] A transport device for culture medium for neuronal cells includes a protective shell with a column, on which spherical blocks are arranged at equal intervals, and a support frame with perforations, wherein a push plate is movably disposed in the perforations and engages with the arc surface of the spherical blocks.

[0008] The support frame is movably provided with a base plate for assembling elastic components, and the base plate mates with a circular hole opened on the support frame.

[0009] Preferably, a plurality of sliders are radially slidably disposed in the circular holes on the support frame, and an arc-shaped pressure plate is fixedly installed at the end of each slider.

[0010] Preferably, a spring is fixedly installed at the end of the slider component.

[0011] Preferably, a rubber pad is fixedly installed on the inner arc-shaped side of the pressure plate.

[0012] Preferably, a connecting plate connected to the slider is fixedly installed on the push plate.

[0013] Preferably, the connecting plates are symmetrically arranged on both sides of the spring.

[0014] Preferably, an elastic bladder in the shape of a partial sphere is fixedly installed on the end face of the base plate.

[0015] Preferably, an elastic column is fixedly installed in the elastic bladder.

[0016] Preferably, the apex of the elastic bladder is compressed and deformed, and cooperates with the adjacent support frame to form a depression.

[0017] Preferably, the elastic bladder is a rubber bladder.

[0018] In the above technical solution, the present invention provides a neuronal cell culture medium transport device with the following beneficial effects: by placing the culture bottle on the base plate, the elastic element deforms due to gravity. At this time, the center of gravity of the culture bottle will shift downward to below the support frame, so that the support frame and the base plate provide stable positioning for the culture bottle. At the same time, the shifted center of gravity makes it easier for the perforation position to move above the sphere. When the column tilts with the protective shell, the support frame can remain vertical or nearly vertical under the action of gravity. Compared with the traditional tilting method, it can provide better anti-tilting and shaking function for the culture bottle, so that there are fewer bubbles generated by the shaking of the culture medium in the culture bottle and less damage to the cells. Attached Figure Description

[0019] To more clearly illustrate the technical solutions in the embodiments of this application or the prior art, the drawings used in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in this utility model. For those skilled in the art, other drawings can be obtained based on these drawings.

[0020] Figure 1 A schematic diagram of the protective shell and its internal columns and single support frame provided in this embodiment of the utility model;

[0021] Figure 2 A schematic diagram of the support frame provided in an embodiment of this utility model;

[0022] Figure 3 A sectional view of the side portion of the column and support frame assembly provided in this embodiment of the utility model;

[0023] Figure 4 This is a schematic diagram of the circumferential distribution of the slider component provided in an embodiment of the present utility model.

[0024] Explanation of reference numerals in the attached figures:

[0025] 1. Protective shell; 11. Column; 12. Ball block; 2. Bearing frame; 21. Perforation; 22. Elastic element; 23. Base plate; 24. Elastic bladder; 241. Recess; 242. Elastic column; 3. Sliding block; 32. Pressure plate; 33. Rubber pad; 34. Connecting plate; 35. Push plate. Detailed Implementation

[0026] To enable those skilled in the art to better understand the technical solution of this utility model, the present utility model will be further described in detail below with reference to the accompanying drawings.

[0027] like Figure 1-4 As shown, a neuronal cell culture medium transport device includes a protective shell 1 with a column 11, on which spherical blocks 12 are arranged at equal intervals, and a support frame 2 with a perforation 21, in which a pusher plate 35 is movably disposed and engages with the arc surface of the spherical blocks 12.

[0028] A base plate 23 for assembling elastic elements 22 is movably mounted on the support frame 2, and the base plate 23 mates with the round hole opened on the support frame 2.

[0029] Specifically, the protective shell 1 has openings on both sides to allow it to be lifted and placed on a mobile trolley. This is existing technology and will not be described in detail here. Four columns 11 are arranged in a group, and multiple groups are arranged equidistantly in the protective shell 1.

[0030] Furthermore, the support frame 2 is installed equidistantly on a set of columns 11, and the elastic element 22 is specifically a tension spring.

[0031] Furthermore, the inner diameter of the perforation 21 is larger than the diameter of the ball block 12, and the gap between the two allows the support frame 2 to swing freely (the swing angle is 0-30°, that is, one side of the ball block 12 is the fulcrum, and the other end can have a 30° tilt angle adaptation), so that the support frame 2 can slide down to the predetermined position of the ball block 12. Then, the inner arc surface of the arc-shaped push plate 35 abuts against the side wall of the column 11, so that the support frame 2 is hung above the ball block 12. It also facilitates the swing of the support frame 2. The upper and lower ends of the perforation 21 are rounded to facilitate vertical installation and also to assist in the tilting of the support frame 2.

[0032] The culture flask is placed by passing it through the round hole so that its bottom touches the base plate 23. As the elastic element 22 deforms due to gravity, the center of gravity of the culture flask will shift downward to below the support frame 2. This causes the support frame 2 and the base plate 23 to provide stable positioning for the culture flask. At the same time, the shifted center of gravity makes it easier for the perforation 21 to move above the sphere 12. When the column 11 tilts with the protective shell 1, the support frame 2 can remain vertical or nearly vertical under the action of gravity. Compared with the traditional method of following the tilt, this method can provide better anti-tilt and anti-shaking function for the culture flask, resulting in fewer bubbles generated by the shaking of the culture medium inside the culture flask and less damage to the cells.

[0033] As a further embodiment of this utility model, a plurality of sliders 3 are radially slidably disposed in the circular hole on the support frame 2, and an arc-shaped pressure plate 32 is fixedly installed at the end of the slider 3.

[0034] The square slider 3 guides and limits the movement of the pressure plate 32, and the pressure plate 32 can also form a clamp on the culture bottle, so that the culture bottle can be stably clamped on the support frame 2.

[0035] As another embodiment further provided in this utility model, a spring is fixedly installed at the end of the slider 3.

[0036] Specifically, the side wall of the circular hole of the support frame 2 is provided with a square hole for the sliding block 3 to slide. The two ends of the spring are connected to the sliding block 3 and the square hole by welding. The end of the square hole has an opening towards the base plate 23 so as to leave welding space.

[0037] By using springs, the distance between the arc-shaped center of the push plate 35 and the perforation 21 is greater than the diameter of the ball block 12 in the default state. However, after the springs are squeezed by the side wall of the culture bottle, the distance is made smaller than the diameter, which facilitates the hanging. Therefore, all the support frames 2 on a set of columns 11 are placed at the bottom of the protective shell 1 in advance, and then the required support frames 2 are pulled up to the predetermined position when the culture bottle is placed.

[0038] As another embodiment further provided by this utility model, a rubber pad 33 is fixedly installed on the inner arc-shaped side of the pressure plate 32.

[0039] The rubber pad 33 increases friction when in contact with the culture flask, providing better anti-slip effect and reducing wear on the pressure plate 32. The rounded corners of the rubber pad 33 are thickened to prevent the corners of the polygonal culture flask from being pressed against the adjacent pressure plate 32, thus preventing slippage and impact. The polygonal culture flask can still apply pressure to all springs, and the pressure is sufficient to keep the push plate 35 above the ball block 12 it is pressing against.

[0040] As another embodiment provided in this utility model, a connecting plate 34 connected to the slider 3 is fixedly installed on the push plate 35.

[0041] Specifically, the connecting plate 34 is integrally formed on the slider 3, that is, there are sliders 3 that inherently contain push plates 35.

[0042] The push plate 35 at the top corner of the support frame 2 is connected by two connecting plates 34, which facilitates the push plate 35 to be limited and swing when squeezed by the culture bottle.

[0043] As another embodiment further provided in this utility model, the connecting plate 34 is symmetrically arranged on both sides of the spring.

[0044] The connecting plate 34 can protect the spring between them, and at the same time, it can distribute the force evenly to the two connecting plates 34.

[0045] As another embodiment of this utility model, an elastic bladder 24 in the shape of a partial sphere is fixedly installed on the end face of the base plate 23.

[0046] By having the elastic bladder 24 contact the mouth of the culture flask below, the elastic bladder 24 can increase the friction between adjacent culture flasks, so that the culture flasks connected to each other have a common vertical ability in a vertical state, making the vertical ability stronger, that is, the individual culture flask is less affected by tilting and shaking.

[0047] As another embodiment provided in this utility model, an elastic column 242 is fixedly installed in the elastic bladder 24.

[0048] The elastic column 242 made of rubber provides support for the internal cavity of the elastic bladder 24. It also allows the elastic column 242 to be deformed under pressure when adjacent culture bottles are close together, thus providing vertical buffering and pressure for the culture bottles and preventing the elastic bladder 24 from collapsing at will and affecting the common verticality.

[0049] As another embodiment further provided in this utility model, the apex of the elastic bladder 24 is deformed under pressure and cooperates with the adjacent support frame 2 to form a recess 241.

[0050] The elastic bladder 24, after being squeezed by the nozzle of the culture flask, has a larger concave contact surface, which also enables the elastic bladder 24 to provide a covering seal to the flask opening.

[0051] As another embodiment further provided in this utility model, the elastic bladder 24 is specifically a rubber bladder.

[0052] The elastic bladder 24 made of rubber allows for easy deformation and also adapts well to the contact and sealing between adjacent culture bottles.

[0053] Working principle: The culture flask is placed by passing it through the round hole so that the bottom of the flask touches the base plate 23. As the elastic element 22 deforms due to gravity, the center of gravity of the culture flask will shift to the bottom of the support frame 2. This causes the support frame 2 and the base plate 23 to provide stable positioning for the culture flask. At the same time, the shifted center of gravity makes it easier for the perforation 21 to move above the ball block 12. When the column 11 tilts with the protective shell 1, the support frame 2 can remain vertical or nearly vertical under the action of gravity. Compared with the traditional tilting method, it can provide better anti-tilting and anti-shaking function for the culture flask.

[0054] The foregoing description only illustrates certain exemplary embodiments of the present invention. Undoubtedly, those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A device for transporting culture medium for neuronal cells, characterized in that, It includes a protective shell (1) with a column (11) on which spherical blocks (12) are arranged at equal intervals, and a support frame (2) with a perforation (21) is provided, in which a push plate (35) is movably provided to abut against the arc surface of the spherical block (12). The support frame (2) is movably provided with a base plate (23) for assembling elastic elements (22), and the base plate (23) is matched with a circular hole opened on the support frame (2).

2. The neuronal cell culture medium transport device according to claim 1, characterized in that, Multiple sliders (3) are radially slidably arranged in the circular holes on the support frame (2), and an arc-shaped pressure plate (32) is fixedly installed at the end of the slider (3).

3. The neuronal cell culture medium transport device according to claim 2, characterized in that, A spring is fixedly installed at the end of the slider (3).

4. The neuronal cell culture medium transport device according to claim 2, characterized in that, A rubber pad (33) is fixedly installed on the inner arc-shaped side of the pressure plate (32).

5. The neuronal cell culture medium transport device according to claim 3, characterized in that, A connecting plate (34) connected to the slider (3) is fixedly installed on the push plate (35).

6. The neuronal cell culture medium transport device according to claim 5, characterized in that, The connecting plate (34) is symmetrically arranged on both sides of the spring.

7. The neuronal cell culture medium transport device according to claim 5, characterized in that, The bottom plate (23) has a partially spherical elastic bladder (24) fixedly installed on its end face.

8. The neuronal cell culture medium transport device according to claim 7, characterized in that, An elastic column (242) is fixedly installed in the elastic bladder (24).

9. The neuronal cell culture medium transport device according to claim 7, characterized in that, The elastic bladder (24) is compressed and deformed at the top and cooperates with the adjacent support frame (2) to form a depression (241).

10. A neuronal cell culture medium transport device according to claim 7, characterized in that, The elastic bladder (24) is specifically a rubber bladder.

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