A ketone body semi-quantitative detection device

CN224365969UActive Publication Date: 2026-06-16ZHONGSHAN HOSPITAL FUDAN UNIV

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
ZHONGSHAN HOSPITAL FUDAN UNIV
Filing Date
2025-06-09
Publication Date
2026-06-16

AI Technical Summary

Technical Problem

The lack of auxiliary equipment in the current ketone powder detection process leads to low efficiency in ketone powder application and difficulty in controlling the detection volume, affecting detection efficiency and repeatability.

Method used

A semi-quantitative ketone body detection device was designed, comprising a detection component and a grinding component. The detection component uses guide rails and pushers to assist in the laying of ketone powder, while the grinding component is used for powder grinding to ensure uniform distribution and fixed amount of ketone powder.

Benefits of technology

The increased speed of ketone powder application ensured the stability and efficiency of the detection, and the fine powder particles improved the accuracy of ketone detection.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model relates to detection equipment field especially, more particularly to a kind of ketone body semi-quantitative detection equipment. Including detection box, the section of detection box is rectangular, the upper surface of detection box is equipped with detection assembly, and detection assembly includes two guide rails, two guide rails are all fixed on the upper surface of detection box, the inner wall of guide rail is slidably connected with slider, one push ruler is fixedly connected to the side of two sliders close to each other, the side of two guide rails close to each other is fixedly connected with detection plate, and the surface of detection plate is equipped with several detection holes, detection holes are evenly distributed on the surface of detection plate, and the side of detection box is equipped with rectangular hole. The utility model provides a kind of ketone body semi-quantitative detection equipment has so that detection equipment can be in short time to assist staff to carry out the rapid laying of ketone powder, reduces the workload, and the detection ketone powder volume of each sample is fixed, can guarantee certain detection stability, improves the advantages such as detection efficiency.
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Description

Technical Field

[0001] This utility model relates to the field of detection equipment, and in particular to a semi-quantitative detection device for ketone bodies. Background Technology

[0002] A semi-quantitative ketone body detection device is a device used to detect ketone body content. Ketone body detection is of great significance in diabetes management, diet and nutrition monitoring, health assessment and disease prevention.

[0003] The ketone powder assay, also known as the sodium nitrosoferricyanide method, is a semi-quantitative detection method. The ketone powder is a mixture of sodium nitrosoferricyanide, anhydrous sodium carbonate, and ammonium sulfate prepared in a specific ratio. In an alkaline solution, the ketone bodies (acetoacetic acid and acetone) in the sample react with the sodium nitrosoferricyanide in the ketone powder, producing a purple compound. By observing the intensity of the purple color, the ketone body content in the sample can be determined; the darker the color, the higher the ketone body content. This method is simple to operate and inexpensive, making it suitable not only for rapid identification of ketosis in emergency settings but also for use in grassroots communities or areas with limited economic resources.

[0004] However, those skilled in the art lack auxiliary equipment for ketone powder preparation during the ketone powder method. Manually preparing ketone powder on filter paper is not only inefficient, but also makes it difficult to control the amount poured each time, which seriously affects the detection efficiency and repeatability.

[0005] Therefore, it is necessary to provide a new semi-quantitative ketone body detection device to solve the above-mentioned technical problems. Utility Model Content

[0006] The purpose of this invention is to address the shortcomings of existing technologies by proposing a semi-quantitative detection device for ketone bodies.

[0007] To solve the above technical problems, this utility model provides a semi-quantitative ketone body detection device, comprising: a detection box with a rectangular cross-section; a detection component on the upper surface of the detection box; the detection component including two guide rails, both of which are fixed to the upper surface of the detection box; sliders slidably connected to the inner walls of the guide rails; a push ruler fixedly connected to one side of the two sliders that are close to each other; a detection plate fixedly connected to one side of the two guide rails that are close to each other; a plurality of detection holes evenly distributed on the surface of the detection plate; a rectangular hole on one side of the detection box; filter paper slidably inserted into the inner wall of the rectangular hole; the upper surface of the filter paper adhering to the lower surface of the detection plate; and a mounting hole on one side of the detection box, the inner wall of which is fitted with a waste box.

[0008] The effects achieved by the above components are as follows: by setting up the detection components, the detection equipment can assist the staff in quickly spreading the ketone powder in a short time, reducing the workload. At the same time, the amount of ketone powder detected for each sample is fixed, which can ensure a certain detection stability and improve detection efficiency.

[0009] Preferably, two auxiliary blocks are fixedly connected to one side of the pusher, and the cross-section of the auxiliary blocks is a right trapezoid.

[0010] The effect achieved by the above components is that when the pusher is used to push the ketone powder, the auxiliary block can push the ketone powder at the corner of the detection plate towards the center of the detection plate, thereby preventing the ketone powder from accumulating at the corner of the detection plate.

[0011] Preferably, each of the two sliders is fixedly connected to a screw on the side away from the pusher, and an adjusting ring is threaded onto the arc surface of the screw. A rubber pad is fixedly connected to one side of the adjusting ring, and one side of the rubber pad abuts against the guide rail.

[0012] The effect achieved by the above components is that, by setting the above structure, the pusher can be easily locked when it is not in use.

[0013] Preferably, a handle is fixedly connected to the outer wall of the waste box on the side away from the detection box, and the handle has a "U" shaped cross-section.

[0014] The effect achieved by the above components is that the movable handle can drive the waste box to move, thus achieving the effect of convenient control of the waste box.

[0015] Preferably, a grinding assembly is provided on one side of the outer wall of the detection box. The grinding assembly includes a support plate, a collection box, and a partition. One side of the support plate is fixedly connected to the outer wall of the detection box. The collection box is disposed on the upper surface of the support plate. One side of the partition is fixedly connected to the outer wall of the detection box. A lead screw is threaded through the surface of the partition. A pressing plate is rotatably connected to the lower end of the lead screw. The size of the pressing plate is adapted to the size of the inner wall of the collection box.

[0016] The effect achieved by the above components is that by setting up the grinding components, the mixed ketone powder can be ground to obtain finer powder particles, which are easier to use and dissolve.

[0017] Preferably, a guide rod is slidably provided on the surface of the partition, and the lower end of the guide rod is fixedly connected to the upper surface of the extrusion plate.

[0018] The effect achieved by the above components is that when the screw drives the extrusion plate to move, the guide rod can guide and position the extrusion plate, thereby preventing rotational deviation of the extrusion plate during its movement.

[0019] Preferably, the upper surface of the support plate is provided with a positioning hole, and the collection box is fitted with the inner wall of the positioning hole.

[0020] The effect achieved by the above components is that when it is necessary to grind the ketone powder inside the collection box, the collection box can be placed in the positioning hole, which allows the collection box and the extrusion plate to be quickly aligned.

[0021] Compared with related technologies, the semi-quantitative ketone body detection device provided by this utility model has the following advantages:

[0022] Beneficial effects:

[0023] This invention provides a semi-quantitative ketone body detection device. By setting up detection components, the device can assist staff in quickly spreading ketone powder in a short time, reducing workload. At the same time, the amount of ketone powder detected in each sample is fixed, which can ensure a certain detection stability and improve detection efficiency.

[0024] By setting up a grinding component, the mixed ketone powder can be ground to obtain finer powder particles, making it easier to use and dissolve. Attached Figure Description

[0025] Figure 1 A schematic diagram of the structure of a semi-quantitative ketone body detection device provided by this utility model;

[0026] Figure 2 for Figure 1 The diagram shows the structure of the detection component.

[0027] Figure 3 for Figure 2 The enlarged view of point A shown;

[0028] Figure 4 for Figure 2 A partial structural disassembly diagram of the detection component shown;

[0029] Figure 5 for Figure 1 The diagram shows the structure of the grinding assembly.

[0030] Figure 6 for Figure 5 The diagram shows a partial structural disassembly of the grinding assembly.

[0031] The following are the labeling elements in the diagram: 1. Detection box; 2. Grinding assembly; 21. Support plate; 22. Positioning hole; 23. Collection box; 24. Partition plate; 25. Lead screw; 26. Extrusion plate; 27. Guide rod; 3. Detection assembly; 301. Guide rail; 302. Slider; 303. Push ruler; 304. Detection plate; 305. Detection hole; 306. Rectangular hole; 307. Filter paper; 308. Mounting hole; 309. Waste box; 310. Handle; 311. Auxiliary block; 312. Screw; 313. Adjusting ring; 314. Rubber pad. Detailed Implementation

[0032] To make the objectives, technical solutions, and advantages of this utility model clearer, the present utility model will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present utility model and are not intended to limit the present utility model.

[0033] The specific implementation of this utility model will be described in detail below with reference to specific embodiments.

[0034] Please see Figure 1 The present invention provides a semi-quantitative detection device for ketone bodies, comprising: a detection box 1, wherein the cross-section of the detection box 1 is rectangular.

[0035] The upper surface of the test box 1 is provided with a test component 3, and one side of the outer wall of the test box 1 is provided with a grinding component 2.

[0036] In the embodiments of this utility model, please refer to Figures 2 to 4The detection component 3 includes two guide rails 301, both of which are fixed to the upper surface of the detection box 1. Slider 302s are slidably connected to the inner walls of the guide rails 301. A pusher 303 is fixedly connected to one side of the two sliders 302 that are close to each other. A detection plate 304 is fixedly connected to one side of the two guide rails 301 that are close to each other. Several detection holes 305 are evenly distributed on the surface of the detection plate 304. A rectangular hole 306 is provided on one side of the detection box 1. Filter paper 307 is slidably inserted into the inner wall of the rectangular hole 306. The upper surface of the filter paper 307 is in contact with the lower surface of the detection plate 304. A mounting hole 308 is provided on one side of the detection box 1, and a waste box 309 is attached to the inner wall of the mounting hole 308. By setting up the detection component 3, the detection equipment can assist workers in quickly laying ketone powder in a short time, reducing workload. At the same time, the amount of ketone powder detected in each sample is fixed, ensuring a certain level of detection stability and improving detection efficiency. Two auxiliary blocks 311 are fixedly connected to one side of the pusher 303. The cross-section of the auxiliary blocks 311 is a right trapezoid. When the pusher 303 pushes the ketone powder, the auxiliary blocks 311 can push the ketone powder at the corner of the detection plate 304 towards the center of the detection plate 304, thereby preventing the ketone powder from accumulating at the corner of the detection plate 304. Screws 312 are fixedly connected to the side of each slider 302 away from the pusher 303. Adjusting rings 313 are threaded onto the arc surface of the screws 312. A rubber pad 314 is fixedly connected to one side of the adjusting ring 313, and one side of the rubber pad 314 abuts against the guide rail 301. When the pusher 303 is not in use and needs to be locked, first rotate the adjusting ring 313 to make the rubber pad 314 abut against the guide rail 301, thus locking the pusher 303. When it is necessary to unlock the pusher 303, simply rotate the adjusting ring 313 in the opposite direction to separate it from the guide rail 301. By setting the above structure, the pusher 303 can be easily locked when not in use. A handle 310 is fixedly connected to the outer wall of the waste box 309 on the side away from the detection box 1. The cross-section of the handle 310 is "U" shaped. Moving the handle 310 can move the waste box 309, achieving the effect of convenient control of the waste box 309.

[0037] In the embodiments of this utility model, please refer to Figure 5 and Figure 6The grinding assembly 2 includes a support plate 21, a collection box 23, and a partition 24. One side of the support plate 21 is fixedly connected to the outer wall of the detection box 1. The collection box 23 is disposed on the upper surface of the support plate 21. One side of the partition 24 is fixedly connected to the outer wall of the detection box 1. A lead screw 25 is threaded through the surface of the partition 24, and a pressing plate 26 is rotatably connected to the lower end of the lead screw 25. The size of the pressing plate 26 is adapted to the size of the inner wall of the collection box 23. By setting up the grinding assembly 2, the mixed ketone powder can be ground to obtain finer powder particles, which are easier to use and dissolve. A guide rod 27 is slidably passed through the surface of the partition 24, and the lower end of the guide rod 27 is fixedly connected to the upper surface of the pressing plate 26. When the lead screw 25 drives the pressing plate 26 to move, the guide rod 27 can guide and position the pressing plate 26, thereby preventing the pressing plate 26 from rotating or shifting during its movement. A positioning hole 22 is opened on the upper surface of the support plate 21, and the collection box 23 fits against the inner wall of the positioning hole 22. When it is necessary to grind the ketone powder inside the collection box 23, the collection box 23 can be placed in the positioning hole 22, which allows the collection box 23 to be quickly aligned with the extrusion plate 26.

[0038] The working principle of the semi-quantitative ketone body detection device provided by this utility model is as follows: When it is necessary to use this detection device to detect ketone bodies, first insert filter paper 307 into the rectangular hole 306 to ensure that each detection hole 305 is covered by filter paper 307. Then, pour about 50g of appropriate ketone powder onto the detection plate and push the pusher 303 so that the pusher 303 moves horizontally according to the direction of the guide rail 301. At this time, the pusher 303 can evenly spread the detection ketone powder in the ketone powder detection hole 305. At the same time, excess copper powder will fall from the edge of the detection plate and can be recycled. After the ketone powder is spread, reset the pusher 303 and prepare for subsequent detection. During detection, add 30ul of ketone body sample above the detection hole 305 and wait for 1 minute to allow the chemical reaction to proceed fully. The ketone bodies acetoacetic acid and acetone in the sample react with sodium nitrosoferricyanide in the ketone body powder to produce a purple compound. Observe the color change and compare it with the standard colorimetric card or colorimetric plate to determine the sample. The presence of ketones in the test results is indicated by color changes (no change or only pale yellow or brownish-yellow) for a negative result, pale purple for a weak positive result, and dark purple for a strong positive result. After all wells have been tested, the filter paper 307 is removed and discarded. The waste ketone powder on the filter paper 307 falls into the waste box 309 below, thus completing the ketone detection process. When using the pusher 303 to push the ketone powder, the auxiliary block 311 can push the ketone powder at the corners of the detection plate towards the center, thus preventing the ketone powder from accumulating at the corners. In addition, when the pusher 303 is not in use and needs to be locked, first rotate the adjusting ring 313 to make the rubber pad 314 abut against the guide rail 301 to lock the pusher 303. When it is necessary to unlock the pusher 303, simply rotate the adjusting ring 313 in the opposite direction to separate it from the guide rail 301. Finally, the moving handle 310 can move the waste box 309, achieving the effect of convenient control of the waste box 309.

[0039] When grinding ketone powder is required, first accurately weigh sodium nitrosoferricyanide, ammonium sulfate, and anhydrous sodium carbonate according to the predetermined formula ratio. Pour them into the collection box 23 according to the mass ratio of sodium nitrosoferricyanide:ammonium sulfate:anhydrous sodium carbonate = 50:50:2.5 and mix them thoroughly. Then, rotate the screw 25 to drive the extrusion plate 26, so that the extrusion plate 26 enters the collection box 23 to extrude and grind the mixed ketone powder. Repeatedly rotating the screw 25 forward and backward can continuously perform the grinding operation. When the screw 25 drives the extrusion plate 26 to move, the guide rod 27 can guide and position the extrusion plate 26, thereby preventing the extrusion plate 26 from rotating and deviating during the movement process. In addition, when it is necessary to grind the ketone powder inside the collection box 23, the collection box 23 can be placed in the positioning hole 22, so that the collection box 23 and the extrusion plate 26 can be quickly aligned.

[0040] The circuits and controls involved in this utility model are all existing technologies, and will not be described in detail here.

[0041] The above description is merely an embodiment of this utility model and does not limit the patent scope of this utility model. Any equivalent structural or procedural transformations made based on the description and drawings of this utility model, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this utility model.

Claims

1. A semi-quantitative detection device for ketone bodies, characterized in that, include: A detection box (1) has a rectangular cross-section. A detection component (3) is provided on the upper surface of the detection box (1). The detection component (3) includes two guide rails (301), both of which are fixed to the upper surface of the detection box (1). A slider (302) is slidably connected to the inner wall of each guide rail (301). A pusher (303) is fixedly connected to one side of the two sliders (302) that are close to each other. A detection plate (304) is fixedly connected to one side of the two guide rails (301) that are close to each other. The surface of the detection plate (304) is provided with a plurality of detection holes (305), which are evenly distributed on the surface of the detection plate (304). A rectangular hole (306) is provided on one side of the detection box (1), and a filter paper (307) is slidably inserted into the inner wall of the rectangular hole (306). The upper surface of the filter paper (307) is in contact with the lower surface of the detection plate (304). An installation hole (308) is provided on one side of the detection box (1), and a waste box (309) is attached to the inner wall of the installation hole (308).

2. The semi-quantitative ketone body detection device according to claim 1, characterized in that, Two auxiliary blocks (311) are fixedly connected to one side of the pusher (303), and the cross section of the auxiliary block (311) is a right trapezoid.

3. The semi-quantitative detection device for ketone bodies according to claim 1, characterized in that, Both sliders (302) are fixedly connected to a screw (312) on the side away from the pusher (303). The screw (312) is threaded with an adjusting ring (313) on its arc surface. A rubber pad (314) is fixedly connected to one side of the adjusting ring (313). One side of the rubber pad (314) abuts against the guide rail (301).

4. The semi-quantitative ketone body detection device according to claim 1, characterized in that, A handle (310) is fixedly connected to the outer wall of the waste box (309) on the side away from the detection box (1), and the cross-section of the handle (310) is "U" shaped.

5. The semi-quantitative detection device for ketone bodies according to claim 1, characterized in that, A grinding assembly (2) is provided on one side of the outer wall of the detection box (1). The grinding assembly (2) includes a support plate (21), a collection box (23) and a partition (24). One side of the support plate (21) is fixedly connected to the outer wall of the detection box (1). The collection box (23) is set on the upper surface of the support plate (21). One side of the partition (24) is fixedly connected to the outer wall of the detection box (1). A lead screw (25) is threaded through the surface of the partition (24). A pressing plate (26) is rotatably connected to the lower end of the lead screw (25). The size of the pressing plate (26) is adapted to the size of the inner wall of the collection box (23).

6. The semi-quantitative detection device for ketone bodies according to claim 5, characterized in that, A guide rod (27) is slidably inserted through the surface of the partition (24), and the lower end of the guide rod (27) is fixedly connected to the upper surface of the extrusion plate (26).

7. The semi-quantitative detection device for ketone bodies according to claim 5, characterized in that, The upper surface of the support plate (21) is provided with a positioning hole (22), and the collection box (23) is in contact with the inner wall of the positioning hole (22).