Cell storage device facilitating sampling

Abstract

The utility model discloses a kind of cell storage devices facilitating sampling, including cryopreservation tube, protective shell, cooling liquid installation structure, rotating structure, displacement structure, fixed structure, storage structure, magnetic attraction sampling structure and sampling port, protective shell side is provided with sampling port, protective shell bottom is equipped with rotating structure for adjusting the angle of storage structure, rotating structure outer surface is connected with displacement structure for adjusting the vertical position of storage structure, for placing the storage structure of cryopreservation tube is installed on displacement structure by fixed structure, storage structure is adjusted to sampling port by displacement structure and rotating structure, magnetic attraction sampling structure for extracting single storage structure by magnetic attraction is provided in sampling port, protective shell top is connected cooling liquid installation structure, cooling liquid installation structure lower end is inserted into rotating structure middle. Advantage, cell sample is stored separately, can be single sampling by magnetic attraction, sampling is convenient.

Description

Technical Field

[0001] This utility model relates to a cell storage device that facilitates sampling, and belongs to the technical field of cell storage devices. Background Technology

[0002] Existing cell storage technologies primarily employ cryopreservation methods, including equipment such as liquid nitrogen chambers, liquid nitrogen tanks, cryogenic chambers, and ultra-low temperature freezers. These devices can halt cell activity and prevent cell degradation at low temperatures, thus preserving cells intact for further research. Among these, liquid nitrogen tank technology is the most widely used, ensuring that stored materials reach their optimal state at low temperatures, and it comes in various types, such as ordinary gas tanks, cryogenic gas tanks, magnetic gas tanks, and double-walled gas tanks.

[0003] However, existing cell storage devices can cause the following problems during use:

[0004] The cryopreservation tubes are stored in liquid nitrogen tanks. When they need to be taken out, the entire test tube rack needs to be removed, which results in multiple samplings affecting the preservation environment of other samples.

[0005] If adjacent cryopreservation tubes stored in the same storage device rupture, the leaked sample may contaminate surrounding samples.

[0006] In summary, there is a need for a cell storage device that allows for separate placement of cryovials and facilitates sampling from individual cryovials.

[0007] Chinese Patent Application No. 202121593045.6: The cell storage device for easy sampling includes a box body with a top cover hinged to the top; two mounting plates, both fixedly mounted on the bottom inner wall of the box body; two connecting blocks, both fixedly mounted on the bottom inner wall of the box body; a liquid addition tube, fixedly mounted on one side of the box body and connected to that side; a lifting mechanism, disposed on the box body; and a storage box, disposed on top of the lifting mechanism. The cell storage device for easy sampling provided by this utility model has the advantages of avoiding frostbite to medical personnel caused by liquid nitrogen during sampling, convenient addition of liquid nitrogen, and convenient sampling.

[0008] This application facilitates sampling, but when multiple cryovials are lifted at the same time to remove a single target sample, it affects the preservation environment of other samples. Furthermore, when cryovials are placed side by side, leaked samples may contaminate surrounding samples if they break. Utility Model Content

[0009] The technical problem to be solved by this invention is that when a single target sample is removed, it affects the preservation environment of other samples, and when cryopreservation tubes are placed adjacent to each other, the leaked sample may contaminate the surrounding samples when it breaks.

[0010] To address the aforementioned technical problems, a cell storage device that facilitates sampling is proposed; this is achieved through the following technical solution:

[0011] The device includes cryopreservation tubes, a protective shell, a coolant loading structure, a rotating structure, a displacement structure, a fixing structure, a storage structure, a magnetic sampling structure, and a sampling port. The sampling port is located on the side of the protective shell. A rotating structure for adjusting the angle of the storage structure is installed at the bottom of the protective shell. A displacement structure for adjusting the vertical position of the storage structure is connected to the outer surface of the rotating structure. The storage structure for placing the cryopreservation tubes is installed on the displacement structure via a fixing structure. The storage structure is adjusted to the sampling port via the displacement and rotating structures. A magnetic sampling structure for magnetically extracting individual storage structures is installed inside the sampling port. The coolant loading structure is connected to the top of the protective shell, and the lower end of the coolant loading structure is inserted into the middle of the rotating structure.

[0012] The rotating structure adjusts the horizontal position of the storage structure and cryovials, while the displacement structure adjusts their vertical position. The cryovials are then positioned at the sampling port, and the magnetic suction structure is pushed towards the cryovials. The magnetic suction structure then adsorbs the storage structure, allowing individual cryovials to be removed for convenient sampling. Furthermore, since the cryovials are placed inside the storage structure, ruptured cell samples from the cryovials flow into the storage structure, reducing the possibility of contamination of other samples.

[0013] In a preferred embodiment of the present invention, the rotating structure includes a first drive motor, a connecting frame, and a rotating cylinder. The first drive motor is installed at the bottom of the protective housing and is connected to the rotating cylinder through the connecting frame. The rotating cylinder is provided with multiple limiting grooves, and a displacement structure is installed inside the limiting grooves. The first drive motor drives the connecting frame and the rotating cylinder to rotate, thereby causing the storage structure to rotate to the sampling port.

[0014] In a preferred embodiment of the present invention, the displacement structure includes a threaded rod, a second drive motor, and multiple moving blocks. The threaded rod is rotatably mounted in a limiting groove, and the second drive motor is fixedly mounted on the lower surface of the connecting frame. The lower end of the threaded rod passes through the connecting frame and connects to the drive shaft of the second drive motor. The multiple moving blocks are connected to the threaded rod and are controlled to move up and down by the second drive motor. A fixed structure is connected to the moving blocks. The displacement structure raises and lowers the storage structure to ensure that the multi-layer storage structure can reach the sampling port position.

[0015] In a preferred embodiment of the present invention, a partition plate is provided inside the protective shell, and a circular hole is provided on the partition plate for the connecting frame to pass through. The first drive motor and the second drive motor are installed below the partition plate to avoid the low temperature affecting the operation of the motor.

[0016] In a preferred embodiment of the present invention, the fixing structure includes a mounting block, a mounting clip, and a spring. The mounting block is connected to the surface of the moving block. The mounting clip is connected to the side of the threaded rod of the mounting block. A spring is provided in the middle of the mounting clip to ensure that the mounting clip can clamp the storage structure. The moving block is provided with a groove for placing the storage structure to ensure that the storage structure is stably placed inside the protective shell.

[0017] In a preferred embodiment of the present invention, the storage structure includes a mounting box, the inside of which is provided with a placement hole for storing cryopreservation tubes, and two magnetic suction holes are provided on the side of the mounting box away from the mounting block to facilitate the magnetic suction of the sample structure and removal of the storage structure.

[0018] In a preferred embodiment of the present invention, the magnetic sampling structure includes a limiting frame, magnetic rods, a pull rod, and a locking mechanism. The limiting frame is slidably disposed within the sampling port. Two magnetic rods are provided on the side of the limiting frame corresponding to the magnetic holes, which cooperate with the magnetic holes. A pull rod is fixedly connected to the outside of the limiting frame to control its position. A locking mechanism is provided on the side of the sampling port to fix the position of the limiting frame. The magnetic sampling structure draws out the storage structure, facilitating sampling.

[0019] A preferred embodiment of the present invention is as follows: The fixing lock includes a fixing block, a rotating rod, a locking plate, and a magnetic suction plate. Two fixing blocks are provided on each of the two outer sides of the sampling port. The rotating rod is rotatably connected to the two fixing blocks, and the locking plate is fixedly connected to the rotating rod. The magnetic suction plate is installed on the outer surface of the limiting frame. The locking plate is fixedly connected to the limiting frame through the magnetic suction plate, thereby limiting the position of the limiting frame. When sampling is not required, the fixing lock fixes the position of the magnetic sampling structure to ensure the sealing of the sampling port.

[0020] In a preferred embodiment of the present invention, the coolant filling structure includes a top cover, a filling port, and a coolant storage tank. The top cover is connected to the top of the protective shell, and the coolant storage tank is fixedly connected to the lower surface of the top cover. A filling port for adjusting the coolant in the coolant storage tank is provided in the middle of the top cover, making it convenient to add coolant at any time.

[0021] In a preferred embodiment of the present invention, the protective shell is provided with a sealing door for inserting cryopreservation tubes, which facilitates the storage of samples.

[0022] The advantages of this utility model compared with the prior art are:

[0023] 1. The rotating structure adjusts the horizontal position of the storage structure and cryotube, and the displacement structure adjusts the vertical position of the storage structure and cryotube. The cryotube is adjusted to the sampling port, and the magnetic sampling structure is pushed towards the cryotube. The magnetic sampling structure attracts the storage structure, and then the individual cryotube is taken out for easy sampling.

[0024] 2. The cryovials are placed inside the storage structure. If the cell sample from a ruptured cryovial flows into the storage structure, the possibility of contamination of other samples is reduced.

[0025] 3. Add coolant after placing the cryovials to reduce the possibility of medical staff getting frostbite while storing the cryovials. Attached Figure Description

[0026] Figure 1 The figure shown is a three-dimensional structural diagram of this utility model. Figure 1 ;

[0027] Figure 2 The figure shown is a three-dimensional structural diagram of this utility model. Figure 2 ;

[0028] Figure 3 The figure shown is a three-dimensional structural diagram of the present invention without a top cover.

[0029] Figure 4 The diagram shown is a schematic representation of the structure of this utility model without a base plate.

[0030] Figure 5 The diagram shown is a schematic representation of the internal structure of this utility model. Figure 1 ;

[0031] Figure 6 The diagram shown is a schematic representation of the internal structure of this utility model. Figure 2 ;

[0032] Figure 7 The figure shown is a cross-sectional view of the internal structure of this utility model;

[0033] Figure 8 The diagram shows the fixing structure and storage structure of this utility model. Figure 1 ;

[0034] Figure 9 The diagram shows the fixing structure and storage structure of this utility model. Figure 2 ;

[0035] Figure 10 The image shows the sampling process inside the magnetic sampling structure of this invention. Figure 6 Schematic diagram of part A in the middle

[0036] Figure 11 The diagram shown is a schematic of the fixed lock structure of this utility model.

[0037] Explanation of reference numerals in the attached drawings: 1. Protective outer casing; 2. Coolant filling structure; 21. Top cover; 22. Filling port; 23. Coolant storage tank; 3. Rotating structure; 31. First drive motor; 32. Connecting frame; 33. Rotating cylinder; 34. Limiting groove; 4. Displacement structure; 41. Threaded rod; 42. Second drive motor; 43. Moving block; 5. Fixing structure; 51. Mounting block; 52. Mounting clamp; 53. Spring; 6. Storage structure; 61. Mounting box; 62. Placement hole; 63. Magnetic suction hole; 7. Magnetic sampling structure; 71. Limiting frame; 72. Magnetic suction rod; 73. Pull rod; 74. Fixing lock; 741. Fixing block; 742. Rotating rod; 743. Locking plate; 744. Magnetic suction plate; 8. Sampling port; 9. Divider plate; 10. Sealing door. Detailed Implementation

[0038] The following will refer to the appendix in the embodiments of this utility model. Figures 1-11 The technical solutions in the embodiments of this utility model will be described in detail below. Example

[0039] like Figures 1-11 As shown, a cell storage device for easy sampling includes cryovials, a protective shell 1, a coolant filling structure 2, a rotating structure 3, a displacement structure 4, a fixing structure 5, a storage structure 6, a magnetic sampling structure 7, and a sampling port 8.

[0040] The protective shell 1 is a hollow cylindrical shell. The protective shell 1 is equipped with a sampling port 8 and a sealing door 10 for inserting cryopreservation tubes. The protective shell 1 has an opening for installing a coolant loading structure 2. The protective shell 1 is equipped with a rotating structure 3 and a displacement structure 4. The storage structure 6 is installed on the displacement structure 4 through a fixing structure 5. The sampling port 8 is equipped with a magnetic sampling structure 7. When the magnetic sampling structure 7 is not in use, it is fixedly installed on the sampling port 8 by a fixing lock 74. At this time, the sampling port 8 is sealed. When sampling is required, the fixing lock 74 is opened to take samples.

[0041] The coolant filling structure 2 is fixedly installed on the upper end of the protective shell 1 and is used to fill the coolant into the protective shell 1. The coolant filling structure 2 includes a top cover 21, a filling port 22 and a coolant storage tank 23. The top cover 21 is fixedly installed on the protective shell 1 by a magnetic absorbing piece 744. The coolant storage tank 23 is welded to the center of the lower surface of the top cover 21. The center of the top cover 21 is provided with a filling port 22 corresponding to the coolant storage tank 23 for replenishing the coolant inside the coolant storage tank 23.

[0042] When the coolant loading structure 2 is damaged due to low temperature, the magnetic chuck 744 can be opened to replace the coolant loading structure 2, ensuring the normal operation of the device and preventing the cell storage environment from being destroyed due to the damage to the coolant loading structure 2.

[0043] The bottom of the protective shell 1 is equipped with a rotating structure 3 for adjusting the angle of the storage structure 6. The rotating structure 3 includes a first drive motor 31, a connecting frame 32, and a rotating cylinder 33. The base of the first drive motor 31 is installed at the bottom of the protective shell 1 via a magnetic absorbing piece 744. The output end of the first drive motor 31 is connected to the lower surface of the connecting frame 32. A partition plate 9 is provided at the bottom inside the protective shell 1. A circular hole for the connecting frame 32 to pass through is provided in the middle of the partition plate 9. The connecting frame 32 passes through the partition plate 9 and is located at the center inside the protective shell 1. By setting the partition plate 9, the low temperature of the cell storage area above the partition plate 9 inside the protective shell 1 is reduced to the effect of the first drive motor 31 installed below the partition plate 9.

[0044] This embodiment employs existing insulation measures between the connecting frame 32 and the partition plate 9, including but not limited to the use of sealing strips and the addition of insulation layers, which are technologies well known to those skilled in the art and can be used directly.

[0045] The connecting frame 32 has a groove in the middle, and the lower end of the coolant storage tank 23 is inside the groove. A rotating cylinder 33 is welded to the outer ring of the connecting frame 32. The rotating cylinder 33 is sleeved on the outside of the coolant storage tank 23. The first drive motor 31 is connected to the rotating cylinder 33 through the connecting frame 32. The first drive motor 31 drives the connecting frame 32 to rotate, thereby rotating the rotating cylinder 33 and adjusting the horizontal position of the cryogenic tube in the storage structure 6 installed on the rotating cylinder 33.

[0046] The displacement structure 4 is installed on the rotating structure 3. Multiple vertical limiting grooves 34 are evenly arranged on the outer side of the rotating cylinder 33. A displacement structure 4 is installed inside each vertical limiting groove 34 to adjust the vertical position of the storage structure 6. The displacement structure 4 includes a threaded rod 41, a second drive motor 42 and multiple moving blocks 43. The threaded rod 41 is installed inside the vertical limiting groove 34 through a bearing. The lower end of the threaded rod 41 passes through the connecting frame 32 and connects to the second drive motor 42. The second drive motor 42 is also located below the partition plate 9 to reduce the impact of the low temperature of the cell storage area above the partition plate 9 inside the protective shell 1 on the second drive motor 42 installed below the partition plate 9.

[0047] In this embodiment, eight vertical limiting grooves 34 are evenly arranged on the outer side of the rotating cylinder 33. Two moving blocks 43 are installed on each threaded rod 41. The second drive motor 42 drives the threaded rod 41 to rotate, causing the moving blocks 43 to move up and down inside the limiting grooves 34. The moving blocks 43 are connected to the storage structure 6 through the fixing structure 5. The moving blocks 43 drive the storage structure 6 to move up and down, adjusting the vertical position of the storage structure 6.

[0048] In this embodiment, a small motor is selected for the second drive motor 42. When the first drive motor 31 drives the connecting frame 32 to rotate, the second drive motor 42, which is installed in the limiting groove 34, is also driven to rotate. Therefore, the selection of a small motor reduces the drive load of the second drive motor 42 and saves energy.

[0049] The fixed structure 5 includes a mounting block 51, a mounting clip 52 and a spring 53. The mounting block 51 is welded to the moving block 43 of the displacement structure 4. The upper surface of the moving block 43 is provided with a mounting groove at the end away from the threaded rod 41, and the storage structure 6 is placed in the mounting groove.

[0050] An elastic mounting clip 52 is welded onto the mounting block 51. A spring 53 is fixedly installed in the middle of the elastic mounting clip 52 near the mounting block 51. The section of the elastic mounting clip 52 away from the mounting block 51 clamps the storage structure 6. The spring 53 ensures that the mounting clip 52 can stably clamp the storage structure 6 and prevent the storage structure 6 from accidentally slipping off.

[0051] The clamping force of the elastic mounting clip 52 is calculated through multiple tests based on the weight of the storage device and the cryopreservation tubes and cells stored inside, as well as the inertia generated when the displacement structure 4 and the rotation structure 3 drive its movement. Furthermore, when the magnetic sampling structure 7 moves to the designated sampling position, the storage structure 6 will not be unstable due to the magnetic attraction of the magnetic sampling structure 7 and its magnetic attraction force.

[0052] The storage structure 6 includes a mounting box 61, which is a rectangular box made of PC material. The mounting box 61 has a placement hole 62 in the middle for storing cryopreservation tubes. The side wall of the placement hole 62 is provided with a wear-resistant plastic layer of PC material to reduce the possibility of damage to the cryopreservation tubes inside the placement hole 62. The side of the mounting box 61 away from the mounting block 51 is provided with two magnetic suction holes 63, which, together with the magnetic sampling structure 7, facilitate the removal of individual storage structures 6.

[0053] The sampling port 8 of the protective shell 1 is provided with an installation track. The installation track consists of four thin plastic sheets, which are welded around the sampling port 8. The magnetic sampling structure 7 is installed inside the installation track. The length of the installation track is sufficient for the magnetic sampling structure 7 to slide inside, and it will not fall off during the sliding process, nor will it affect the operation of the rotating structure 3 and the displacement structure 4.

[0054] The magnetic sampling structure 7 includes a limiting frame 71, a magnetic suction rod 72, a pull rod 73, and a fixing lock 74. The limiting frame 71 is slidably installed inside the mounting guide rail, and the pull rod 73 is welded to the outer surface of the limiting frame 71. Pulling the pull rod 73 can adjust the position of the limiting frame 71 inside the mounting rail.

[0055] The limiting frame 71 is provided with a limiting sealing protrusion at one end near the center of the protective shell 1. The pull rod 73 pulls the limiting frame 71 out of the limiting sealing protrusion and tightly fits it against the side of the mounting rail. At this time, the sampling port 8 is sealed, reducing low temperature loss.

[0056] Two magnetic rods 72, corresponding to the size of the magnetic holes 63, are welded to the inner side of the limiting frame 71. The magnitude of the attraction between the magnetic rods 72 and the magnetic holes 63 is calculated based on multiple tests of the weight of the storage device and the cryopreservation tubes and cells stored inside, as well as the clamping force of the elastic mounting clip 52. When the magnetic rods 72 have not yet entered the magnetic holes 63, the magnetic attraction between them will not affect the stable installation of the storage device. When the magnetic rods 72 are inserted into the magnetic holes 63, the magnetic attraction is greater than the force of the mounting clip 52, ensuring that the storage device can be pulled out.

[0057] When sampling is not required, the pull rod 73 pulls the limit frame 71 out of the limit sealing protrusion and tightly fits the side of the mounting rail, thus sealing the sampling port 8. Then, the position of the limit frame 71 is fixed by the fixing lock 74 to ensure the sealing of the sampling port 8.

[0058] When sampling, push the pull rod 73 into the protective shell 1, align the magnetic suction rod 72 with the magnetic suction hole 63 of the storage structure 6, insert the magnetic suction rod 72 into the magnetic suction hole 63, and pull the pull rod 73 to pull out the storage structure 6 together, thus realizing the sampling of a single storage structure 6. Because the storage structure 6 and the cryovial are both made of plastic and are relatively lightweight, the operator does not need to exert much effort to pull them out. Moreover, since the cryovial is installed inside the storage structure 6, the possibility of accidental damage during the removal process is small. Even if the cryovial is damaged, the cells inside will enter the storage structure 6 and will not contaminate the samples inside other storage structures 6.

[0059] The fixed lock 74 includes a fixed block 741, a rotating rod 742, a locking plate 743, and a magnetic suction plate 744. Two fixed blocks 741 are provided on each of the two outer sides of the sampling port 8. The two fixed blocks 741 are rotatably connected to the rotating rod 742 through bearings. The locking plate 743 is fixedly connected to the rotating rod 742. The inner wall of the locking plate 743 is provided with a magnetic suction block corresponding to the magnetic suction plate 744. The magnetic suction plate 744 is installed on the outer surface of the limiting frame 71. The locking plate 743 is fixedly connected to the limiting frame 71 through the cooperation of the magnetic suction plate 744 and the magnetic suction block, thus limiting the position of the limiting frame 71. When sampling is not required, the fixed lock 74 fixes the position of the magnetic sampling structure 7, ensuring the sealing of the sampling port 8.

[0060] In this embodiment, a rotating structure 3 and a displacement structure 4 are installed inside the protective shell 1. The storage structure 6 is mounted on the displacement structure 4 through a fixing structure 5. The rotating structure 3 drives the displacement structure 4 to rotate and adjust the horizontal position of the storage structure 6. The displacement structure 4 adjusts the vertical position of the storage structure 6. When sampling is required, the storage structure 6 and the cryopreservation tube are moved to the position of the corresponding sampling port 8 through the rotating structure 3 and the displacement structure 4. Then, the magnetic sampling structure 7 is used to take the sample, which is convenient and quick. A single storage structure 6 can be taken out.

[0061] The control system in this embodiment adopts a closed-loop position control system in the automatic position control system, which consists of a motor, a power driver, a controller and a position sensor. It has been used in the control of CNC machine tools and is a technology well known to those skilled in the art, and can be used directly.

[0062] In this embodiment, the protective shell 1 is provided with a sealing door 10 for placing cryovials. Before adding coolant to the coolant loading structure 2, cryovials and cell samples are added to the storage structure 6 through the sealing door 10. When placing the samples, the position of the storage structure 6 is adjusted to ensure that each storage structure 6 can place samples through the sealing door 10. After storage is completed, the sealing door 10 is closed.

[0063] In this embodiment, the first drive motor 31 and the second drive motor 42 are KECM series servo motors, which can be used in low-temperature environments. KECM series servo motors are remotely controlled through encoders, drivers and control circuits. The control method is existing technology, such as servo motors in CNC machine tools to ensure the precise movement of tools or worktables.

[0064] The working process of this embodiment:

[0065] First, the sample is placed into the device through the sealing door 10, and then the sealing door 10 is closed. When sampling is required, the rotating structure 3 and the displacement structure 4 are activated to drive the storage structure 6 to the position corresponding to the sampling port 8, depending on the storage location of the different samples. The fixing lock 74 is opened and the corresponding storage structure 6 is taken out through the magnetic sampling structure 7, which realizes the individual retrieval of the sample and ensures that the sample is of the correct type. The sample is stored in the storage structure 6. If the cryopreservation tube is damaged and the internal sample flows into the storage structure 6, it will not contaminate other samples inside.

[0066] The above embodiments are only for illustrating the technical concept of this utility model and should not be construed as limiting the scope of protection of this utility model. Any modifications made to the technical solution based on the technical concept proposed by this utility model shall fall within the scope of protection of this utility model.

Claims

1. A cell storage device for easy sampling, comprising cryovials, characterized in that: It also includes a protective shell (1), a coolant loading structure (2), a rotating structure (3), a displacement structure (4), a fixing structure (5), a storage structure (6), a magnetic sampling structure (7), and a sampling port (8). The protective shell (1) has a sampling port (8) on its side. The protective shell (1) has a rotating structure (3) installed at its bottom for adjusting the angle of the storage structure (6). The rotating structure (3) has a displacement structure (4) connected to its outer surface for adjusting the vertical position of the storage structure (6). The storage structure (6) for placing cryopreservation tubes is installed on the displacement structure (4) through the fixing structure (5). The storage structure (6) is adjusted to the sampling port (8) through the displacement structure (4) and the rotating structure (3). The sampling port (8) has a magnetic sampling structure (7) for magnetically extracting a single storage structure (6). The top of the protective shell (1) is connected to the coolant loading structure (2). The lower end of the coolant loading structure (2) is inserted into the middle of the rotating structure (3).

2. The cell storage device for easy sampling according to claim 1, characterized in that: The rotating structure (3) includes a first drive motor (31), a connecting frame (32) and a rotating cylinder (33). The first drive motor (31) is installed at the bottom of the protective shell (1). The first drive motor (31) is connected to the rotating cylinder (33) through the connecting frame (32). The rotating cylinder (33) is provided with multiple limiting grooves (34). The displacement structure (4) is installed inside the limiting grooves (34).

3. The cell storage device for easy sampling according to claim 2, characterized in that: The displacement structure (4) includes a threaded rod (41), a second drive motor (42), and multiple moving blocks (43). The threaded rod (41) is rotatably installed in the limiting groove (34). The second drive motor (42) is fixedly installed on the lower surface of the connecting frame (32). The lower end of the threaded rod (41) passes through the connecting frame (32) and connects to the drive shaft of the second drive motor (42). Multiple moving blocks (43) are connected to the threaded rod (41) and are controlled to move up and down by the second drive motor (42). A fixed structure (5) is connected to the moving blocks (43).

4. The cell storage device for easy sampling according to claim 3, characterized in that: The protective housing (1) has a partition plate (9) inside, and the partition plate (9) has a round hole for the connecting frame (32) to pass through.

5. The cell storage device for easy sampling according to claim 3, characterized in that: The fixed structure (5) includes a mounting block (51), a mounting clip (52) and a spring (53). The mounting block (51) is connected to the surface of the movable block (43). The mounting block (51) is connected to the mounting clip (52) on the side of the threaded rod (41). A spring (53) is provided in the middle of the mounting clip (52) to ensure that the mounting clip (52) can clamp the storage structure (6). The movable block (43) is provided with a groove for placing the storage structure (6).

6. The cell storage device for easy sampling according to claim 1, characterized in that: The storage structure (6) includes a mounting box (61), which has a placement hole (62) for storing cryopreservation tubes inside. The side of the mounting box (61) away from the mounting block (51) has two magnetic suction holes (63).

7. The cell storage device for easy sampling according to claim 6, characterized in that: The magnetic sampling structure (7) includes a limiting frame (71), a magnetic rod (72), a pull rod (73), and a fixing lock (74). The limiting frame (71) is slidably set inside the sampling port (8). Two magnetic rods (72) are provided inside the limiting frame (71) on the side corresponding to the magnetic hole (63) to cooperate with the magnetic hole (63). A pull rod (73) for controlling the position of the limiting frame (71) is fixedly connected to the outside of the limiting frame (71). A fixing lock (74) for fixing the position of the limiting frame (71) is provided on the side of the sampling port (8).

8. The cell storage device for easy sampling according to claim 7, characterized in that: The fixed lock (74) includes a fixed block (741), a rotating rod (742), a locking plate (743), and a magnetic plate (744). Two fixed blocks (741) are provided on each of the two outer sides of the sampling port (8). The rotating rod (742) is rotatably connected to the two fixed blocks (741). The locking plate (743) is fixedly connected to the rotating rod (742). The magnetic plate (744) is installed on the outer surface of the limiting frame (71). The locking plate (743) is fixedly connected to the limiting frame (71) through the magnetic plate (744) to limit the position of the limiting frame (71).

9. The cell storage device for easy sampling according to claim 1, characterized in that: The coolant filling structure (2) includes a top cover (21), a filling port (22) and a coolant storage tank (23). The top cover (21) is connected above the protective shell (1). The coolant storage tank (23) is fixedly connected to the lower surface of the top cover (21). A filling port (22) for adjusting the coolant in the coolant storage tank (23) is provided in the middle of the top cover (21).

10. The cell storage device for easy sampling according to claim 1, characterized in that: The protective casing (1) is provided with a sealing door (10) for inserting cryopreservation tubes.

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