A multi-channel pipette verification sample addition device

Abstract

This utility model relates to the field of pipette calibration and sample application technology, and in particular to a multi-channel pipette calibration and sample application device; it includes a first frame and a second frame that are spliced ​​together, with several channels adapted to pipette tips opened on the splicing surface of the first frame and the second frame, the axis of the channel forming a 45° angle with the horizontal plane; elastic clamping components are symmetrically arranged on the inner sidewall of each channel, the elastic clamping components are configured to clamp weighing cups of different inner diameters and provide reliable fixation; this device can adapt to multi-channel pipettes, realize the calibration process of all channels in one sample application operation, and flexibly match weighing cups of different inner diameters and provide reliable clamping, so as to greatly improve the calibration efficiency of multi-channel pipettes.

Description

Technical Field

[0001] This utility model relates to the field of pipette calibration and sample application technology, and in particular to a multi-channel pipette calibration and sample application device. Background Technology

[0002] The pipette calibration device is a key piece of equipment specifically used for metrological performance verification of pipettes. As an indispensable precision liquid transfer tool in laboratories across industries such as medical and health, testing and inspection, biopharmaceuticals, and environmental monitoring, the accuracy and consistency of pipette values ​​directly affect the reliability of experimental results. Therefore, in accordance with relevant metrological verification procedures, it is necessary to periodically use the calibration device in conjunction with high-precision electronic balances to verify and calibrate key parameters such as volumetric accuracy and repeatability of pipettes to ensure their performance meets standard requirements.

[0003] However, traditional pipette calibration devices have significant shortcomings when used in conjunction with multichannel pipettes. Multichannel pipettes should be able to transfer liquids from multiple channels in a single operation, but existing calibration devices are typically designed as single-channel devices, accommodating only a single weighing cup. This makes the calibration process extremely cumbersome: for each channel and each set calibration point, such as the maximum, minimum, and intermediate ranges, and the required number of repeated measurements (usually six), the operator must individually add, weigh, and record the sample for each channel before switching to the next channel and repeating the same operation. This "serial" approach results in extremely low calibration efficiency, is time-consuming and labor-intensive, and contradicts the original intention of multichannel pipettes to improve efficiency. Furthermore, traditional devices also have limitations in adapting to weighing cups with specific inner diameters required for different volume ranges and in providing stable clamping. Therefore, there is an urgent need to design a dedicated sample dispensing device that can be adapted to multi-channel pipettes, enable the calibration of all channels in a single sample dispensing operation, and flexibly match weighing cups with different inner diameters while providing reliable clamping, so as to significantly improve the calibration efficiency of multi-channel pipettes.

[0004] Therefore, this application provides a multi-channel pipette calibration and sample application device to solve the problems mentioned in the background art. Utility Model Content

[0005] The purpose of this invention is to provide a multi-channel pipette calibration and sample application device to solve the problems of existing calibration and sample application devices being unsuitable for multi-channel pipettes, having low efficiency, and being unable to flexibly match weighing cups of different inner diameters and provide reliable clamping.

[0006] To solve the above-mentioned technical problems, this utility model provides a multi-channel pipette calibration and sampling device, including a first frame and a second frame spliced ​​together. Several channels adapted to pipette tips are opened on the splicing surface of the first frame and the second frame. The axis of the channel forms a 45° angle with the horizontal plane.

[0007] Each channel has symmetrically arranged elastic clamping components on its inner sidewall. These components are configured to hold weighing cups of different inner diameters and provide reliable fixation.

[0008] A further improvement of this utility model is that the number of channels is eight.

[0009] A further improvement of this utility model is that: the elastic clamping components are respectively disposed on the inner sidewall of the first frame channel and the inner sidewall of the second frame channel.

[0010] A further improvement of the present invention is that the elastic clamping assembly includes an upper limit groove and a lower limit groove formed on the inner side wall of the channel. The upper limit groove and the lower limit groove are coaxially arranged along the axial direction of the channel. An arc-shaped spring is provided between the upper limit groove and the lower limit groove, and the bending direction of the arc-shaped spring is towards the central axis of the channel.

[0011] A further improvement of this utility model is that: a fixing rod is provided in the middle of the upper limit groove and the middle of the lower limit groove along the radial direction of the channel; a fixing hole is opened at the upper end of the spring piece, and the fixing rod in the upper limit groove passes through and fixes it; an adjustment elongated hole extending along the axial direction of the channel is opened at the lower end of the spring piece, and the lower end of the spring piece passes through the adjustment elongated hole through the fixing rod in the lower limit groove, so that the lower end of the spring piece can move relative to the fixing rod along the axial direction of the channel, so as to realize the clamping adaptation and reliable fixation of weighing cups with different inner diameters.

[0012] A further improvement of this utility model is that the surface of the spring is covered with a rubber coating.

[0013] A further improvement of this utility model is that: several mounting columns are provided on the splicing surface of the first frame, and several mounting holes corresponding to the positions of the mounting columns are opened on the splicing surface of the second frame, with the mounting columns and mounting holes being interference fits.

[0014] A further improvement of this utility model is that handles are provided on both sides of the first frame and the second frame, and the two ends of the handles are fixedly connected to the first frame and the second frame, so as to connect and fix the two frames and facilitate the overall carrying of the device.

[0015] By adopting the above technical solution, this utility model has the following beneficial effects:

[0016] 1. This utility model provides a multi-channel pipette calibration sample application device. This device is equipped with eight channels whose axes are at a 45° angle to the horizontal plane, and with symmetrically arranged elastic clamping components. It can directly adapt to 1-8 channel pipettes for sample application. Compared with traditional single-channel devices that require operation of each channel individually, this utility model can collect samples from all channels at the same time in one sample application operation, which significantly simplifies the calibration process of multi-channel pipettes and greatly improves the calibration efficiency.

[0017] 2. This utility model provides a multi-channel pipette calibration and sample application device. This device, with its 45° angle between the channel axis and the horizontal plane, and its self-adjustable elastic clamping assembly, is particularly suitable for pipette calibration requirements and electronic balance weighing requirements. The 45° tilt angle facilitates the smooth detachment of the pipette tip from the liquid surface after sample application, reducing liquid residue and ensuring accurate sample volume. Simultaneously, this angle optimizes the placement of the weighing cup on the electronic balance, ensuring the stability of the weighing process and the reliability of the results.

[0018] 3. This utility model provides a multi-channel pipette calibration and sample application device. This device, by setting an arc-shaped spring with an adjustable elongated hole in the elastic clamping assembly, and cooperating with the fixing rod in the upper and lower limit grooves, allows the lower end of the spring to move along the channel axis, realizing flexible matching and reliable clamping of weighing cups with different inner diameters. This design ensures that weighing cups of various specifications required for calibration of different ranges can be firmly fixed in the channel, meeting the volume measurement needs of multi-channel pipettes at different calibration points. Attached Figure Description

[0019] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0020] Figure 1 This is a schematic diagram of a multi-channel pipette calibration and sample application device.

[0021] Figure 2 A schematic diagram of a multi-channel pipette calibration and sample application device with a weighing cup installed;

[0022] Figure 3 An exploded view of a multichannel pipette calibration and sample application device;

[0023] Figure 4 This is a schematic diagram of the structure of the first frame of this utility model;

[0024] Figure 5 for Figure 4 An enlarged schematic diagram of part A in the middle;

[0025] Figure 6 This is a schematic diagram of the structure of the second frame of this utility model;

[0026] Figure 7 This is a schematic diagram of the structure of the spring sheet of this utility model.

[0027] Reference numerals: 1. First frame; 2. Second frame; 3. Channel; 4. Weighing cup; 5. Elastic clamping assembly; 51. Upper limit slot; 52. Lower limit slot; 53. Spring piece; 54. Fixing rod; 55. Fixing hole; 56. Adjusting elongated hole; 6. Mounting post; 7. Mounting hole; 8. Handle. Detailed Implementation

[0028] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0029] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0030] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0031] The present invention will be further explained below with reference to specific embodiments.

[0032] like Figures 1-7As shown, this embodiment provides a multi-channel pipette calibration and sample application device, comprising a first frame 1 and a second frame 2 connected together. These two frames are joined together by their splicing surfaces, and several channels 3 for fitting pipette tips are formed on these surfaces. Preferably, the number of channels 3 is set to eight to match common eight-channel pipettes. The axes of all channels 3 are at a 45° angle to the horizontal plane. This 45° tilt angle has a dual function: firstly, it meets the requirements of the pipette calibration procedure, facilitating the smooth removal of the pipette tip from the liquid surface after sample application, effectively reducing liquid residue and ensuring the accuracy of the transferred liquid volume; secondly, this angle optimizes the position and orientation of the weighing cup 4 when placed on the electronic balance, ensuring stable and reliable weighing results. The device's detachable first frame 1 and second frame 2 facilitate maintenance and cleaning, while the eight tilted channels 3 directly meet the efficient and compliant calibration requirements of multi-channel pipettes, laying the foundation for subsequent operations.

[0033] like Figure 4 , Figure 5 , Figure 7 As shown, in this embodiment, elastic clamping components 5 are symmetrically arranged on the inner wall of each channel 3. The elastic clamping components 5 are located on the inner wall of the channel 3 of the first frame 1 and the second frame 2, respectively. The core function of the elastic clamping components 5 is to securely clamp weighing cups 4 with different inner diameters, ensuring their reliable fixation during the calibration process. The elastic clamping components 5 specifically include an upper limit groove 51 and a lower limit groove 52 opened on the inner wall of the channel 3, which are precisely coaxially arranged along the axial direction of the channel 3. Between the upper limit groove 51 and the lower limit groove 52, an arc-shaped spring piece 53 with its curvature direction facing the central axis of the channel 3 is installed. In order to enhance the friction and protect the surface of the weighing cup 4, the surface of the spring piece 53 is covered with a rubber coating. Structurally, a fixing rod 54 is arranged radially along the channel 3 in the middle of both the upper limit groove 51 and the lower limit groove 52. A fixing hole 55 is opened at the upper end of the spring piece 53, and a fixed connection is achieved by the fixing rod 54 passing through the upper limit groove 51. The lower end of the spring piece 53 has an adjustment elongated hole 56 extending along the axis of the channel 3. A fixing rod 54 in the lower limiting groove 52 passes through the adjustment elongated hole 56, allowing the lower end of the spring piece 53 to slide within a certain range relative to the fixing rod 54 along the axis of the channel 3. This allows the spring piece 53 to automatically adjust its curvature according to the outer diameter of the weighing cup 4 placed inside, utilizing its own elastic deformation to generate appropriate clamping force, thus reliably adapting to and fixing weighing cups 4 with different inner diameters. The elastic clamping assembly 5, with its adjustable arc-shaped spring piece 53 structure, achieves adaptive clamping of weighing cups 4 of various sizes. Combined with the friction-enhancing and anti-slip effect provided by the rubber coating, it ensures the stability and safety of the weighing cup 4 in various verification operations.

[0034] like Figure 1 , Figure 3 , Figure 4 , Figure 6 As shown in this embodiment, to ensure the overall rigidity and stability of the first frame 1 and the second frame 2 after splicing, several mounting posts 6 are provided on the splicing surface of the first frame 1, while mounting holes 7, corresponding one-to-one in number and position to the mounting posts 6, are provided on the splicing surface of the second frame 2. The mounting posts 6 and the mounting holes 7 are tightly connected by an interference fit, which can effectively resist vibration and impact during operation and prevent loosening or displacement between the frames. In addition, handles 8 are provided on both sides of the first frame 1 and the second frame 2 of the device. The two ends of each handle 8 are firmly connected to the corresponding first frame 1 and second frame 2. The handles 8 not only facilitate the operator to carry and move the device as a whole, but also firmly connect and fix the two originally independent frames on both sides, further enhancing the structural integrity and stability of the entire device. The interference fit structure of the mounting posts 6 and the mounting holes 7, as well as the connecting handles 8 on both sides, together constitute the rigid connection frame of the device, ensuring the structural stability and durability of the device during frequent use. At the same time, the design of the handles 8 also greatly facilitates the handling and operation of the device.

[0035] This utility model also provides the operating principle of a multi-channel pipette calibration and sampling device:

[0036] During operation, the first frame 1 and the second frame 2 are first tightly assembled into a single unit using the mounting posts 6 on their splicing surfaces and the interference-fit mounting holes 7. Then, based on the number of channels of the multi-channel pipette to be calibrated and the required calibration range, a corresponding number of weighing cups 4 with the appropriate inner diameter are selected and placed into the bottom of the corresponding number of inclined channels 3 on the device. During placement, the outer wall of the weighing cup 4 contacts and pushes against the arc-shaped spring pieces 53 in the elastic clamping components 5 symmetrically arranged on the inner wall of the channel 3. Due to the sliding engagement between the adjusting elongated hole 56 and the fixing rod 54 in the lower limit groove 52, the lower end of the spring piece 53 can move along the axis of the channel 3, causing elastic deformation of the spring piece 53 and utilizing the friction provided by the rubber coating on its surface, thereby automatically adapting to and firmly clamping the weighing cups 4 with different inner diameters. After assembling and fixing the weighing cups 4, the operator can hold the handles 8 on both sides of the device, which connect and fix the two frames and facilitate carrying, and place the entire device stably on the operating table. Next, using the eight-channel pipette to be calibrated, all its tips are aligned with the corresponding channels 3 of the device at once, and the sample is added. Simultaneously, solution is drawn or injected into each weighing cup 4. This process requires only one sample addition to collect samples from all channels 3. Finally, the operator lifts the device again using handle 8 and removes it from the operating table.

[0037] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of this utility model, and are not intended to limit it. Although the utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this utility model.

Claims

1. A multi-channel pipette verification dosing device, characterized in that, It includes a first frame (1) and a second frame (2) that are spliced ​​together. Several channels (3) for pipette tips are opened on the splicing surface of the first frame (1) and the second frame (2). The axis of the channel (3) is at a 45° angle to the horizontal plane. Each channel (3) has symmetrically arranged elastic clamping components (5) on its inner sidewall. The elastic clamping components (5) are configured to clamp weighing cups (4) with different inner diameters and provide reliable fixation.

2. A multi-channel pipette verification dosing device according to claim 1, characterized in that There are eight channels (3).

3. A multi-channel pipette verification dosing device according to claim 1, characterized in that The elastic clamping components (5) are respectively disposed on the inner side wall of the channel (3) of the first frame (1) and the inner side wall of the channel (3) of the second frame (2).

4. The multi-channel pipette verification dosing device of claim 1, wherein, The elastic clamping assembly (5) includes an upper limit groove (51) and a lower limit groove (52) formed on the inner side wall of the channel (3). The upper limit groove (51) and the lower limit groove (52) are coaxially arranged along the axial direction of the channel (3). An arc-shaped spring piece (53) is provided between the upper limit groove (51) and the lower limit groove (52). The bending direction of the arc-shaped spring piece (53) is towards the central axis of the channel (3).

5. A multi-channel pipette verification dosing device according to claim 4, characterized in that Fixing rods (54) are provided radially along the channel (3) in the middle of the upper limit groove (51) and the middle of the lower limit groove (52); a fixing hole (55) is opened at the upper end of the spring piece (53), and it is fixed by passing through the fixing rod (54) in the upper limit groove (51); an adjustment elongated hole (56) extending axially along the channel (3) is opened at the lower end of the spring piece (53), and the lower end of the spring piece (53) passes through the fixing rod (54) in the lower limit groove (52) into the adjustment elongated hole (56), so that the lower end of the spring piece (53) can move relative to the fixing rod (54) along the axial direction of the channel (3), so as to realize the clamping adaptation and reliable fixation of weighing cups (4) with different inner diameters.

6. A multi-channel pipette verification dosing device according to claim 4, characterized in that The surface of the shrapnel (53) is covered with a rubber coating.

7. The multi-channel pipette verification dosing device of claim 1, wherein, The first frame (1) has several mounting posts (6) on its splicing surface, and the second frame (2) has several mounting holes (7) on its splicing surface corresponding to the positions of the mounting posts (6). The mounting posts (6) and the mounting holes (7) are interference fit.

8. The multi-channel pipette verification dosing device of claim 1, wherein, Handles (8) are provided on both sides of the first frame (1) and the second frame (2). The two ends of the handles (8) are fixedly connected to the first frame (1) and the second frame (2) respectively, so as to connect and fix the two frames and facilitate the overall carrying of the device.

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