Micropipette for Biological Agent Samples

Abstract

This utility model relates to the field of biopharmaceutical technology and discloses a micro-particle sample dispensing needle holder for biopharmaceutical samples. The needle holder includes a syringe tube, with a needle holder mechanism fixedly connected to the bottom of the outer wall of the syringe tube for securing the sample dispensing needle. A cleaning mechanism is fixedly connected to the middle of the inner wall of the needle holder mechanism for cleaning the sample dispensing needle. The needle holder mechanism includes a base, which is fixedly connected to the bottom of the outer wall of the syringe tube. A fixing tube is fixedly connected to the top of the inner wall of the base, and a clamping tube is fixedly connected to the bottom of the outer wall of the fixing tube. Multiple telescopic brackets are rotatably connected to the outer wall of the clamping tube, and positioning components are fixedly connected to the outer wall of the fixing tube. In this utility model, when the sample dispensing needle holder is in operation, the syringe tube provides support, and the base is connected to the clamping tube through the fixing tube, enhancing stability and achieving high compatibility. It eliminates the need to replace the entire needle holder; adjustment of the positioning components and telescopic brackets is sufficient for adaptation, offering high convenience.

Description

Technical Field

[0001] This utility model relates to the field of biopharmaceutical technology, and in particular to a micro-particle sample dispensing needle holder for biopharmaceuticals. Background Technology

[0002] Biological agent samples refer to various substance samples derived from living organisms and prepared through biotechnology, used for research, detection, diagnosis, treatment, and production purposes. They possess biological activity and specific biological characteristics. The sampling needle is a precision tool used to accurately transfer trace volumes of liquid and is the main component for realizing the operation of micro-volume transfer, dispensing, and dilution of samples.

[0003] A micro-pipette holder for biological agents is a precision component used for micro-pipette operations of biological agents. Its main function is to fix and support the micro-pipette needle, ensuring that the needle maintains a stable position and angle when aspirating and transferring biological agents, thereby guaranteeing the accuracy, repeatability, and safety of the dispensing. However, in existing micro-pipette holders for biological agents, the needle holder is for a specific diameter and model of needle, resulting in poor compatibility. Dedicated needle holders cannot be adapted to dispensing needles from other brands, which requires additional needle holder replacement when changing or upgrading equipment, increasing costs and operational complexity. Utility Model Content

[0004] To overcome the above shortcomings, this utility model provides a micro-dispensing needle holder for biological agent samples, which aims to improve the poor compatibility of the existing technology, where the dedicated needle holder cannot be adapted to other dispensing needles, resulting in the need to replace the needle holder when the equipment is replaced or upgraded.

[0005] To achieve the above objectives, the present invention adopts the following technical solution: a micro-particle sample dispensing needle holder for biological agents, comprising a needle tube, a needle holder mechanism fixedly connected to the bottom of the outer wall of the needle tube, the needle holder mechanism being used to fix the sample dispensing needle, a cleaning mechanism fixedly connected to the middle of the inner wall of the needle holder mechanism, the cleaning mechanism being used to clean the sample dispensing needle; the needle holder mechanism comprises a base, the base being fixedly connected to the bottom of the outer wall of the needle tube, a fixing tube fixedly connected to the top of the inner wall of the base, a clamping tube fixedly connected to the bottom of the outer wall of the fixing tube, multiple telescopic frames rotatably connected to the outer wall of the clamping tube, and a positioning component fixedly connected to the outer wall of the fixing tube.

[0006] As a further description of the above technical solution:

[0007] The positioning component includes a spring, which is fixedly connected to the middle of the inner wall of the fixing tube. Clamping plates are fixedly connected to adjacent sides of the outer wall of the spring. A telescopic ring is slidably connected to the middle of the outer wall of the fixing tube, and a fixing block is fixedly connected to one side of the outer wall of the telescopic ring.

[0008] As a further description of the above technical solution:

[0009] The cleaning mechanism includes an air pump, which is fixedly connected to the bottom of the inner wall of the base. An air inlet pipe is connected to one side of the bottom of the air pump. An air outlet pipe is fixedly connected to the top of the outer wall of the air pump. Multiple exhaust holes are opened in the middle of the outer wall of the air outlet pipe. An air inlet hole is fixedly connected to the bottom of the outer wall of the air inlet pipe. A fixing component is fixedly connected to one side of the outer wall of the air pump.

[0010] As a further description of the above technical solution:

[0011] The fixing component includes a fixing ring, which is fixedly connected to one side of the outer wall of the air pump. Support frames are fixedly connected to the left and right sides of the bottom of the air pump, and a fixing pad is fixedly connected to the middle of the outer wall of the support frame.

[0012] As a further description of the above technical solution:

[0013] A fixing pad is fixedly connected to the top of the outer wall of the syringe, and a fixing bracket is fixedly connected to the front side of the outer wall of the telescopic ring.

[0014] As a further description of the above technical solution:

[0015] A needle sleeve is fixedly connected to the bottom of the outer wall of the needle tube, and a push rod is fixedly connected to the top of the outer wall of the needle tube.

[0016] As a further description of the above technical solution:

[0017] Multiple sealing rings are fixedly connected around the outer wall of the air outlet pipe, and a heat dissipation plate is fixedly connected to one side of the outer wall of the air pump.

[0018] As a further description of the above technical solution:

[0019] A wear-resistant pad is fixedly connected to the top of the outer wall of the clamping tube, and a limit groove is formed on the front side of the outer wall of the needle tube.

[0020] This utility model has the following beneficial effects:

[0021] 1. In this utility model, when the sample needle holder is working, the needle tube provides support, the base is connected to the clamping tube through the fixing tube, after the sample needle is inserted, the spring of the positioning component in the fixing tube pushes the clamping plate to initially clamp, the telescopic ring and the fixing block adjust the force, and the telescopic frame on the outer wall of the clamping tube adjusts with the insertion depth to enhance stability and achieve high compatibility. There is no need to replace the entire needle holder; the positioning component and the telescopic frame can be adjusted to adapt, which is highly convenient.

[0022] 2. In the design of the cleaning mechanism of this utility model, the fixed component of the air pump ensures that the air pump can operate stably during the working process. When the air pump is started, air is drawn in through the air inlet on the air inlet pipe, and then the drawn-in air is pressurized. During the cleaning process, the airflow can effectively remove dust and dirt attached to the surface of the object, thereby achieving the purpose of cleaning. Attached Figure Description

[0023] Figure 1 This is a three-dimensional view of the micro-dispensing needle holder for biological agents proposed in this utility model;

[0024] Figure 2 This is a front view of the micro-dispensing needle holder for biological agents proposed in this utility model;

[0025] Figure 3 This is a structurally exploded view of the micro-dispensing needle hub for biological agents proposed in this utility model;

[0026] Figure 4 This is a partial structural breakdown diagram of the micro-dispensing needle hub for biological agents proposed in this utility model;

[0027] Figure 5 This is a partial structural diagram of the micro-dispensing needle hub for biological agents proposed in this utility model.

[0028] Legend:

[0029] 1. Needle tube; 2. Needle seat mechanism; 201. Base; 202. Fixing tube; 203. Clamping tube; 204. Telescopic frame; 205. Positioning component; 2051. Spring; 2052. Clamping plate; 2053. Telescopic ring; 2054. Fixing block; 3. Cleaning mechanism; 301. Air pump; 302. Air inlet pipe; 303. Air outlet pipe; 304. Exhaust port; 305. Air inlet port; 306. Fixing component; 3061. Fixing ring; 3062. Support frame; 3063. Fixing pad one; 4. Fixing pad two; 5. Fixing frame; 6. Needle sheath; 7. Push rod; 8. Sealing ring; 9. Heat sink; 10. Wear-resistant pad; 11. Limiting groove. Detailed Implementation

[0030] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0031] Reference Figure 1 , Figure 3 and Figure 4This utility model provides an embodiment of a micro-particle sample dispensing needle holder for biological agents, comprising a needle tube 1, a needle holder mechanism 2 fixedly connected to the bottom of the outer wall of the needle tube 1 for fixing the dispensing needle, and a cleaning mechanism 3 fixedly connected to the middle of the inner wall of the needle holder mechanism 2 for cleaning the dispensing needle; the needle holder mechanism 2 includes a base 201 fixedly connected to the bottom of the outer wall of the needle tube 1, a fixing tube 202 fixedly connected to the top of the inner wall of the base 201, and a fixing tube 202 fixedly connected to the bottom of the outer wall of the fixing tube 202. The clamping tube 203 has multiple telescopic frames 204 rotatably connected around its outer wall. The positioning component 205 is fixedly connected around its outer wall. The positioning component 205 includes a spring 2051, which is fixedly connected to the middle of the inner wall of the fixed tube 202. Clamping plates 2052 are fixedly connected to adjacent sides of the outer wall of the spring 2051. A telescopic ring 2053 is slidably connected to the middle of the outer wall of the fixed tube 202. A fixing block 2054 is fixedly connected to one side of the outer wall of the telescopic ring 2053.

[0032] Specifically, when the micro-sample dispensing needle hub of this biological agent is in operation, the needle tube 1 provides basic support, and the needle hub mechanism 2 at the bottom of its outer wall undertakes the main function of fixing the dispensing needle. The base 201 is connected to the clamping tube 203 in layers through the fixing tube 202. When the dispensing needle is inserted, the positioning component 205 on the inner wall of the fixing tube 202 plays a role, and the spring 2051 pushes the clamping plate 2052 to flexibly clamp the dispensing needle. The sliding telescopic ring 2053 cooperates with the fixing block 2054 to adjust the clamping force according to the diameter of the dispensing needle. The telescopic frame 204 on the outer wall of the clamping tube 203 can rotate and adjust with the insertion depth to enhance the fixing stability. This multi-level clamping structure can firmly fix dispensing needles of different specifications and achieve high compatibility. When cleaning the equipment, the cleaning mechanism 3 in the middle of the inner wall of the needle hub mechanism 2 can clean and maintain the dispensing needle. When the equipment is replaced or upgraded, due to the compatibility of each component, it is not necessary to replace the entire needle hub. Only the positioning component 205 and the telescopic frame 204 need to be adjusted to adapt to the new dispensing needle, which improves the convenience of operation.

[0033] Reference Figure 1 , Figure 2 and Figure 5 The cleaning mechanism 3 includes an air pump 301, which is fixedly connected to the bottom of the inner wall of the base 201. An air inlet pipe 302 is connected to one side of the bottom of the air pump 301. An air outlet pipe 303 is fixedly connected to the top of the outer wall of the air pump 301. Multiple exhaust holes 304 are opened in the middle of the outer wall of the air outlet pipe 303. An air inlet hole 305 is fixedly connected to the bottom of the outer wall of the air inlet pipe 302. A fixing component 306 is fixedly connected to one side of the outer wall of the air pump 301. The fixing component 306 includes a fixing ring 3061, which is fixedly connected to one side of the outer wall of the air pump 301. A support frame 3062 is fixedly connected to the left and right sides of the bottom of the air pump 301. A fixing pad 3063 is fixedly connected to the middle of the outer wall of the support frame 3062.

[0034] Specifically, the air pump 301 is installed on the bottom of the inner wall of the base 201 via a fixing component 306. A fixing ring 3061 secures the side wall of the air pump 301, while bottom support brackets 3062, in conjunction with fixing pads 3063, enhance stability and prevent shaking during operation. The air pump 301 draws air in through the bottom air inlet pipe 302 and the air inlet hole 305. After pressurization, the air is delivered through the top air outlet pipe 303 and discharged through multiple exhaust holes 304 in the middle, forming an airflow cleaning component. Throughout the process, the fixing component 306 ensures the stability of the air pump 301, working together to complete the air intake and exhaust, achieving cleaning. The air pump 301 is supported by the bottom support brackets 3062 and fixing pads 3063 on the inner wall of the base 201, and further secured by the fixing rings 3061 and the fixing component 306. After the air pump 301 is started, outside air enters the air inlet pipe 302 through the air inlet hole 305, is pressurized, delivered through the air outlet pipe 303, and ejected from the exhaust holes 304, cleaning surrounding components and achieving the gas cleaning function.

[0035] Reference Figure 1 , Figure 2 and Figure 3 A fixing pad 4 is fixedly connected to the top of the outer wall of the needle tube 1; a fixing bracket 5 is fixedly connected to the front side of the outer wall of the telescopic ring 2053; a needle sleeve 6 is fixedly connected to the bottom of the outer wall of the needle tube 1; a push rod 7 is fixedly connected to the top of the outer wall of the needle tube 1; multiple sealing rings 8 are fixedly connected to the four sides of the outer wall of the air outlet tube 303; a heat dissipation plate 9 is fixedly connected to one side of the outer wall of the air pump 301; a wear-resistant pad 10 is fixedly connected to the top of the outer wall of the clamping tube 203; and a limit groove 11 is opened on the front side of the outer wall of the needle tube 1.

[0036] Specifically, the needle tube 1 is fixed and its position is adjusted by the clamping tube 203 in the needle holder mechanism 2. The push rod 7 at the top of the needle tube 1 can control the internal liquid push, and the needle sleeve 6 at the bottom protects the needle tip. The air pump 301 of the cleaning mechanism 3 takes in air through the air inlet pipe 302 and exhausts air through the air outlet pipe 303. The air outlet pipe 303 is equipped with a sealing ring 8 to ensure airtightness and achieve gas cleaning of related components. At the same time, the fixing pad 4 on the outer wall of the needle tube 1 enhances the stability of the top connection, the heat dissipation plate 9 on the side of the air pump 301 assists in heat dissipation, and the limiting groove 11 on the front side of the needle tube 1 limits its extension or movement range. The entire system completes the fixing, operation and auxiliary functions of the needle tube 1 through the coordinated cooperation of various components.

[0037] Working principle: When this micro-needle hub for biological agents is in operation, the needle tube 1 provides basic support for the overall structure, and the needle hub mechanism 2 at the bottom of its outer wall undertakes the core function of fixing the needle: the base 201 is connected to the clamping tube 203 through the fixing tube 202. When the needle is inserted, the positioning component 205 on the inner wall of the fixing tube 202 first plays its role. The spring 2051 pushes the clamping plate 2052 through its own elasticity, initially forming a flexible clamp for the needle. At the same time, the sliding telescopic ring 2053, together with the fixing block 2054, can flexibly adjust the clamping force according to the diameter of the needle. The multiple telescopic brackets 204 on the outer wall of the clamping tube 203 can rotate and adjust with the insertion depth of the sampling needle, further enhancing the fixation stability. The multi-level clamping structure ensures that sampling needles of different specifications can be firmly fixed, achieving high compatibility. When cleaning is required during equipment operation, the cleaning mechanism 3 in the middle of the inner wall of the needle holder mechanism 2 can clean and maintain the sampling needle. When the equipment is replaced or upgraded, due to the adaptability of each component to different sampling needles, there is no need to replace the entire needle holder. Only the positioning component 205 and the telescopic brackets 204 need to be adjusted to adapt to the new sampling needle, improving the ease of operation.

[0038] The air pump 301 is securely mounted on the bottom inner wall of the base 201 via a fixing assembly 306. A fixing ring 3061 secures the side wall of the air pump 301, while support brackets 3062 on the left and right sides of the bottom, along with fixing pads 3063, enhance the overall stability of the installation and prevent shaking during operation. The air pump 301 draws in air through the air inlet 305 via the air inlet pipe 302 on one side of the bottom. After internal pressurization, the air is delivered through the air outlet pipe 303 on the top of the outer wall and discharged through multiple exhaust holes 304 in the middle of the outer wall of the air outlet pipe 303, forming an airflow to clean the relevant components. Throughout the process, the fixing assembly 306 ensures the stable operation of the air pump 301. The air intake and exhaust structures work together to complete the intake and exhaust of gas, achieving a cleaning effect. The working principle of the cleaning mechanism 3 is as follows: the air pump 301 is stably supported by the support frame 3062 and the fixing pad 3063 at the bottom of the inner wall of the base 201, and further fixed by the fixing ring 3061 and the fixing component 306 on one side of the outer wall of the air pump 301; after the air pump 301 is started, the outside air enters the air intake pipe 302 through the air intake hole 305, and is then pressurized by the air pump 301 and transported through the air outlet pipe 303. It is then sprayed out from the multiple exhaust holes 304 in the middle of the air outlet pipe 303, forming an airflow to clean the surrounding components, thus realizing the gas cleaning function of the device.

[0039] Finally, it should be noted that the above description is only a preferred embodiment of the present utility model and is not intended to limit the present utility model. Although the present utility model has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present utility model should be included within the protection scope of the present utility model.

Claims

1. A biological sample micro-adding needle seat comprising a needle tube (1), characterized in that: A needle seat mechanism (2) is fixedly connected to the bottom of the outer wall of the needle tube (1). The needle seat mechanism (2) is used to fix the sample needle. A cleaning mechanism (3) is fixedly connected to the middle of the inner wall of the needle seat mechanism (2). The cleaning mechanism (3) is used to clean the sample needle. The needle holder mechanism (2) includes a base (201), which is fixedly connected to the bottom of the outer wall of the needle tube (1). A fixing tube (202) is fixedly connected to the top of the inner wall of the base (201), and a clamping tube (203) is fixedly connected to the bottom of the outer wall of the fixing tube (202). Multiple telescopic frames (204) are rotatably connected around the outer wall of the clamping tube (203), and a positioning component (205) is fixedly connected around the outer wall of the fixing tube (202).

2. The biological agent sample micro- spotting needle hub of claim 1, wherein: The positioning component (205) includes a spring (2051), which is fixedly connected to the middle of the inner wall of the fixing tube (202). Clamping plates (2052) are fixedly connected to adjacent sides of the outer wall of the spring (2051). A telescopic ring (2053) is slidably connected to the middle of the outer wall of the fixing tube (202), and a fixing block (2054) is fixedly connected to one side of the outer wall of the telescopic ring (2053).

3. The biological sample micro- spotting pin holder of claim 1, wherein: The cleaning mechanism (3) includes an air pump (301), which is fixedly connected to the bottom of the inner wall of the base (201). An air inlet pipe (302) is connected to one side of the bottom of the air pump (301). An air outlet pipe (303) is fixedly connected to the top of the outer wall of the air pump (301). Multiple exhaust holes (304) are opened in the middle of the outer wall of the air outlet pipe (303). An air inlet hole (305) is fixedly connected to the bottom of the outer wall of the air inlet pipe (302). A fixing component (306) is fixedly connected to one side of the outer wall of the air pump (301).

4. The biological sample microsampler needle hub of claim 3, wherein: The fixing component (306) includes a fixing ring (3061), which is fixedly connected to one side of the outer wall of the air pump (301). A support frame (3062) is fixedly connected to the left and right sides of the bottom of the air pump (301), and a fixing pad (3063) is fixedly connected to the middle of the outer wall of the support frame (3062).

5. The biological sample micro- spotting pin holder of claim 2, wherein: The top of the outer wall of the needle tube (1) is fixedly connected to a fixing pad 2 (4), and the front side of the outer wall of the telescopic ring (2053) is fixedly connected to a fixing bracket (5).

6. The biological sample micro- spotting pin holder of claim 5, wherein: A needle sleeve (6) is fixedly connected to the bottom of the outer wall of the needle tube (1), and a push rod (7) is fixedly connected to the top of the outer wall of the needle tube (1).

7. The biological sample micro- spotting pin holder of claim 3, wherein: Multiple sealing rings (8) are fixedly connected around the outer wall of the air outlet pipe (303), and a heat sink plate (9) is fixedly connected to one side of the outer wall of the air pump (301).

8. The biological sample micro- spotting pin holder of claim 1, wherein: A wear-resistant pad (10) is fixedly connected to the top of the outer wall of the clamping tube (203), and a limiting groove (11) is opened on the front side of the outer wall of the needle tube (1).

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