An electric scraper device based on profiled surface and negative pressure cooperation

Abstract

The utility model relates to the technical field of pharmaceutical preparation engineering, and disclose a kind of electric doctor blade device based on profiled surface and negative pressure coordination, including the bottom end fixed connection of air pump main body is connected steel pipe, and the output end fixed connection of air pump main body is suction pipe.The utility model places installation block and scraping structure in the inside of medicine bottle by hand gripping rubber sleeve, then moves connection steel pipe and adheres steel bar scraper to the inner wall of medicine bottle, and the bottom end of steel bar scraper adheres to the round bottom of medicine bottle, at this time, rotating medicine bottle, under the action of steel bar scraper, the medicine on the inner wall of medicine bottle is scraped on the surface of steel bar scraper, and after scraping a certain amount, medicine can slowly fall into the inside of collecting groove, this design can make the arc of steel bar scraper more adhere to round bottom flask, enhance the contact area of steel bar scraper and the inner wall of medicine bottle, so that steel bar scraper can scrape most of the medicine in the inner wall of flask in the process of scraping, improve scraping efficiency.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical preparation engineering technology; more specifically, it relates to an electric scraper device based on the synergy of contoured curved surface and negative pressure. Background Technology

[0002] Statistics show that 40% of globally marketed drugs are poorly soluble, and the proportion of poorly soluble drug candidates in the research and development stage is as high as 90%. Drug solubility has become one of the major challenges restricting new drug development. Converting drugs into phospholipid complexes to increase solubility and thus improve their bioavailability in the body has become one of the most active research directions in pharmaceutical science. After solvent evaporation, a phospholipid complex with a certain viscosity can be obtained in the round-bottom flask. The product can then be collected by physical scraping or dissolution transfer. The main advantages of physical scraping compared to dissolution transfer are: simplified operation steps, avoidance of residual risks caused by introducing additional solvents, reduction of degradation or loss that may be caused by secondary dissolution of the drug, and preservation of the original physical morphology of the complex (such as an amorphous state), which helps maintain its stability and dissolution characteristics.

[0003] As described in patent CN217700517U, while using an adjustable-angle multi-arc scraper can improve operational convenience, it relies on manual adjustment of the angled support rod angle (requiring repeated calibration to the appropriate position), increasing operation time. Furthermore, its universal scraper design struggles to accurately match the curvature of the inner walls of flasks of different sizes, resulting in high resistance when scraping phospholipid complexes with high viscosity, leading to excessive drug residue and severely affecting the accuracy of compounding rate calculations. Patent CN221361728U proposes using an inflatable rubber bladder to clean the flask wall, which simplifies the process, but the bladder material easily adheres to highly viscous drugs, resulting in incomplete cleaning. Simultaneously, the bladder inflation pressure is difficult to control precisely, potentially damaging the amorphous structure of the drug, and the lack of an effective drug collection mechanism poses a risk of secondary contamination. Therefore, there is an urgent need for an electric scraper device based on contoured curved surfaces and negative pressure synergy to solve these problems. Summary of the Invention

[0004] In order to overcome the above-mentioned defects of the prior art, the present invention provides an electric scraper device based on contoured curved surface and negative pressure synergy, so as to solve the problems existing in the background art.

[0005] This utility model provides the following technical solution: an electric scraper device based on contoured curved surface and negative pressure synergy, comprising:

[0006] An air pump body, with a connecting steel pipe fixedly connected to the bottom end of the air pump body, and an air intake pipe fixedly connected to the output end of the air pump body, with the air intake pipe located inside the connecting steel pipe. A mounting block is threadedly connected to the bottom end of the connecting steel pipe, and a scraping structure is provided on one side of the outer surface of the mounting block.

[0007] The scraping structure includes a steel scraper and a collection groove, and the top of the outer surface of the steel scraper is fixedly connected to one side of the outer surface of the mounting block.

[0008] Preferably, a rubber sleeve is fitted over the top of the outer surface of the connecting steel pipe, which enhances the comfort of the worker's hand grip.

[0009] Preferably, the scraping structure further includes a collection groove, which is located on one side of the outer surface of the steel scraper. A connecting pipe is fixedly connected inside the steel scraper, and one end of the connecting pipe passes through the steel scraper and extends into the interior of the mounting block. One end of the connecting pipe is connected to the bottom end of the suction pipe. A negative pressure hole is provided on one side of the outer surface of the connecting pipe, and multiple sets of negative pressure holes are provided. This design allows for the scraping of a larger amount of medicine at a time.

[0010] Preferably, the steel scraper is made of stainless steel and has a thickness of 1mm. This design, combined with the inherent toughness of stainless steel, allows the steel scraper to fit more closely to the inner wall of the medicine bottle.

[0011] Preferably, both the outer shape of the steel scraper and the inner shape of the collection trough are arc-shaped. This design allows all the medicine scraped by the steel scraper to fall into the collection trough.

[0012] Preferably, the diameter of the negative pressure hole is 0.5 mm. This design prevents the scraped medicine from falling directly into the negative pressure hole during adsorption.

[0013] The technical effects and advantages of this utility model are as follows: This utility model places the mounting block and scraping structure inside the medicine bottle by holding a rubber sleeve, and then moves the connecting steel pipe to attach the steel scraper to the inner wall of the medicine bottle with the bottom end of the steel scraper attached to the round bottom of the medicine bottle. At this time, rotating the medicine bottle allows the medicine on the inner wall of the medicine bottle to be scraped onto the surface of the steel scraper under the action of the steel scraper. After scraping a certain amount, the medicine can slowly fall into the collection tank. This design allows the curvature of the steel scraper to fit the round bottom flask better, increasing the contact area between the steel scraper and the inner wall of the medicine bottle. This allows the steel scraper to scrape most of the medicine from the inner wall of the flask during the scraping process, improving the scraping efficiency. At the same time, the collection tank allows the scraped medicine to fall into the collection tank, enabling more medicine to be scraped at one time and preventing the medicine from easily falling off the surface of the steel scraper, thereby improving the overall practicality of the equipment to a certain extent.

[0014] By activating the air pump, the suction pipe gains suction. Since the connecting pipe is connected to the suction pipe, it also gains suction. During the scraping operation with the steel scraper, external air is drawn into the connecting pipe through the negative pressure hole. This design effectively removes highly viscous phospholipid complexes from the flask's inner wall, allowing them to be easily scraped off. This prevents the phospholipid complexes from adhering to the flask's inner wall, reducing drug loss and making subsequent compounding rate calculations more accurate. It also improves the equipment's practicality to a certain extent. Furthermore, its overall structure is simple and reasonable, highly practical, and easy to promote and apply. Attached Figure Description

[0015] Figure 1 This is a three-dimensional structural diagram of the present invention.

[0016] Figure 2 This is an exploded three-dimensional structural diagram of the connecting steel pipe of this utility model.

[0017] Figure 3 This is a three-dimensional exploded view of the scraping structure of this utility model.

[0018] Figure 4 This utility model Figure 3 Enlarged diagram of point A in the middle.

[0019] The attached diagram is labeled as follows: 1. Air pump body; 2. Connecting steel pipe; 3. Suction pipe; 4. Mounting block; 5. Scraping structure; 51. Steel scraper; 52. Collection trough; 53. Connecting pipe; 54. Negative pressure hole. Detailed Implementation

[0020] The technical solution of this utility model will be clearly and completely described below with reference to the accompanying drawings. In addition, the forms of the various structures described in the following embodiments are merely illustrative. The pharmaceutical preparation engineering involved in this utility model is not limited to the structures described in the following embodiments. All other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0021] Example 1

[0022] like Figures 1-4 As shown, this embodiment proposes an electric scraper device based on the synergy of contoured curved surfaces and negative pressure, comprising:

[0023] An air pump body 1 is fixedly connected to a connecting steel pipe 2 at its bottom end, and an air suction pipe 3 is fixedly connected to the output end of the air pump body 1. The air suction pipe 3 is located inside the connecting steel pipe 2. An installation block 4 is threadedly connected to the bottom end of the connecting steel pipe 2, and a scraping structure 5 is provided on one side of the outer surface of the installation block 4.

[0024] The scraping structure 5 includes a steel scraper 51 and a collection groove 52. The top of the outer surface of the steel scraper 51 is fixedly connected to one side of the outer surface of the mounting block 4. The scraping structure 5 also includes a collection groove 52, which is opened on one side of the outer surface of the steel scraper 51. A connecting pipe 53 is fixedly connected inside the steel scraper 51. One end of the connecting pipe 53 passes through the steel scraper 51 and extends into the interior of the mounting block 4. One end of the connecting pipe 53 is connected to the bottom end of the suction pipe 3. A negative pressure hole 54 is opened on one side of the outer surface of the connecting pipe 53. Multiple sets of negative pressure holes 54 are provided. This design allows the negative pressure holes 54 to generate negative pressure under the action of the connecting pipe 53, so that the medicine on the inner wall of the flask can be sucked up. This allows the steel scraper 51 to easily scrape the medicine off the inner wall of the flask during the scraping process.

[0025] A rubber sleeve is fitted on the top of the outer surface of the connecting steel pipe 2. This design, with the elasticity and toughness of the rubber material itself, can enhance the comfort of the staff when holding the equipment.

[0026] The steel scraper 51 is made of stainless steel and has a thickness of 1mm. This design, thanks to the inherent toughness of stainless steel, allows operators to easily adjust the shape of the steel scraper 51 during operation, making it fit more closely to the inner wall of the flask.

[0027] The outer shape of the steel scraper 51 and the inner shape of the collection tank 52 are both arc-shaped. This design can increase the contact area between the steel scraper 51 and the inner wall of the flask, so that the steel scraper 51 can scrape more medicine at a time. After a certain amount of medicine is collected, it can all fall into the collection tank 52, so that the staff can scrape more medicine at a time.

[0028] The diameter of the negative pressure hole 54 is 0.5mm. With the action of multiple negative pressure holes 54, the medicine scraped off by the steel scraper 51 can be adsorbed and fall into the collection tank 52. The size of the negative pressure hole 54 is about 0.5mm, which can appropriately control the suction force of the negative pressure hole 54 and avoid the opening being too large, which would cause the suction force to be too strong and directly suck the medicine into the negative pressure hole 54.

[0029] Working principle: When using the equipment, the installation block 4 and scraping structure 5 are placed inside the medicine bottle by holding the rubber sleeve. Then, the connecting steel pipe 2 is moved to attach the steel scraper 51 to the inner wall of the medicine bottle, with the bottom end of the steel scraper 51 attached to the round bottom of the medicine bottle. At this time, the flask is rotated, and the medicine on the inner wall of the flask is scraped onto the surface of the steel scraper 51 under the action of the steel scraper 51. After scraping a certain amount, it can slowly fall into the collection tank 52. This design allows more medicine to be scraped at one time during the scraping operation, reducing the number of scraping operations and saving scraping time.

[0030] When using the equipment, starting the air pump body 1 will give the suction pipe 3 suction. Since the connecting pipe 53 is connected to the suction pipe 3, the connecting pipe 53 will also have suction. When the steel scraper 51 is scraping, it can create a negative pressure inside the flask, which will draw the drug from the inner wall of the flask, making the drug easy to scrape off by the steel scraper 51. This design makes scraping more efficient and faster, greatly reducing drug loss caused by the high viscosity of the phospholipid complex, and making the subsequent calculation of the compounding rate more accurate. After the steel scraper 51 has finished scraping, first tilt the connecting steel pipe 2 as a whole, and then turn off the air pump body 1. At this time, the adsorption effect of the negative pressure hole 54 can be canceled, preventing the drug from flowing back. Then, remove the mounting block 4 and the scraping structure 5 from the inside of the flask. The above is the complete working principle of this utility model.

[0031] Traditional medicine spoon This scraping device Phospholipid complex residue 10.11 ± 1.2% 4.87 ± 0.3% Single scraping amount 34.82 ±4.8 mg 63.42 ± 4.5 mg Average time to clean a single bottle 6.2 ± 2.4 min 4.1 ± 1.2 min Composite rate 78.22 ± 2.1% 90.13 ± 1.4%

[0032] Finally, the following points should be noted: First, in the description of this application, it should be noted that, unless otherwise specified and limited, the terms "installation", "connection", and "linkage" should be interpreted broadly, and can be mechanical or electrical connections, or internal connections between two components, or direct connections. "Up", "down", "left", "right", etc. are only used to indicate relative positional relationships. When the absolute position of the described object changes, the relative positional relationship may change.

[0033] Secondly: The accompanying drawings of the embodiments disclosed in this utility model only involve the structures involved in the embodiments disclosed in this utility model. Other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of this utility model can be combined with each other.

[0034] In conclusion, the above are merely preferred embodiments of this utility model and are not intended to limit this utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the protection scope of this utility model.

Claims

1. An electrically driven doctor blade device based on the cooperation of a profiling curved surface and negative pressure, characterized in that, include: An air pump body (1) is fixedly connected to a connecting steel pipe (2) at its bottom end, and a suction pipe (3) is fixedly connected to the output end of the air pump body (1). The suction pipe (3) is located inside the connecting steel pipe (2). A mounting block (4) is threadedly connected to the bottom end of the connecting steel pipe (2), and a scraping structure (5) is provided on one side of the outer surface of the mounting block (4). A rubber sleeve is fitted on the top end of the outer surface of the connecting steel pipe (2). The scraping structure (5) includes a steel scraper (51) and a collection groove (52), and the top of the outer surface of the steel scraper (51) is fixedly connected to one side of the outer surface of the mounting block (4). The scraping structure (5) also includes a collection groove (52), which is located on one side of the outer surface of the steel scraper (51). A connecting pipe (53) is fixedly connected inside the steel scraper (51), and one end of the connecting pipe (53) passes through the steel scraper (51) and extends into the interior of the mounting block (4). One end of the connecting pipe (53) is connected to the bottom end of the suction pipe (3). A negative pressure hole (54) is provided on one side of the outer surface of the connecting pipe (53), and multiple sets of negative pressure holes (54) are provided. The diameter of the negative pressure hole (54) is 0.5 mm.

2. The electrically driven doctor blade device based on the cooperation of profiled surface and negative pressure according to claim 1, characterized in that: The steel scraper (51) is made of stainless steel and has a thickness of 1 mm.

3. The electrically driven doctor blade device based on the cooperation of profiled surface and negative pressure according to claim 1, characterized in that: The outer shape of the steel scraper (51) and the inner shape of the collection groove (52) are both set to be arc-shaped.

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