A batch opening and closing device for sterile cryotube caps

Abstract

The utility model embodiment provides a kind of batch opening and closing device for sterile cryogenic tube cover, including the base (1) of placing sterile cryogenic tube rack (10), be connected to the opening and closing component (2) of base (1) and be located on sterile cryogenic tube rack (10) above, the pipe mouth of each sterile cryogenic tube has a sterile cryogenic tube cover (100) sealing sterile cryogenic tube;Opening and closing component (2) includes the rack combination (22) of being able to correspond card to set in the circumferential straight line of each sterile cryogenic tube cover (100) outer wall and circumferential straight line match engagement, each rack combination (22) is used to tighten or loosen corresponding sterile cryogenic tube cover (100) from sterile cryogenic tube;Batch opening and closing device further include the drive component (3) by driving rack combination (22). Realize batch opening or closing sterile cryogenic tube, relative pure manual improves the sealing or opening cover speed of same batch cryogenic tube cover, compared with electric equipment, reduce the risk of cryogenic tube being contaminated.

Description

Technical Field

[0001] This utility model relates to the field of sterile cryopreservation, specifically to a batch opening and closing device for sterile cryopreservation tube caps. Background Technology

[0002] Cryopreservation tubes are medical devices frequently used in the medical field. In the process of developing this utility model, the applicant discovered that the prior art has at least the following problems: cryopreservation tubes not only require high sterility, but also require rapid sealing, or for cryopreservation tubes containing biological samples, rapid opening is also required. However, the electric equipment used in the prior art cannot autoclave. If the caps are manually screwed on or off, especially when there are many cryopreservation tubes, it will greatly reduce the capping or opening speed of the same batch of cryopreservation tubes (it takes about 10 minutes to manually open / close 50 cryopreservation tubes), reduce efficiency, and increase the risk of contamination of the cryopreservation tubes. Utility Model Content

[0003] This utility model provides a batch opening and closing device for sterile cryopreservation tube caps, which can realize batch capping or opening of cryopreservation tubes.

[0004] To achieve the above objectives, this utility model provides a batch opening and closing device for sterile cryopreservation tube caps, including a base for placing a sterile cryopreservation tube rack and an opening and closing component connected to the base and disposed on the sterile cryopreservation tube rack. The sterile cryopreservation tube rack is capable of holding multiple longitudinal columns and multiple transverse columns of sterile cryopreservation tubes, and each sterile cryopreservation tube has a sterile cryopreservation tube cap that seals the sterile cryopreservation tube at its opening.

[0005] The opening and closing assembly includes a rack assembly that can be mechanically driven to engage with the circumferential grooves on the outer wall of each sterile cryotube cap. Each rack assembly is used to tighten or loosen the corresponding sterile cryotube cap from the sterile cryotube.

[0006] The batch opening and closing device for sterile cryopreservation tube caps further includes a drive assembly that drives the rack assembly to rotate the sterile cryopreservation tube caps on the sterile cryopreservation tubes to tighten or loosen the sterile cryopreservation tube caps.

[0007] The above technical solution has the following beneficial effects: After multiple sterile cryovials are loaded with their respective samples, they are placed in the sterile cryovial holders on a sterile cryovial rack. The rack assembly engages with the circumferentially knurled outer wall of the corresponding sterile cryovial cap via a rack assembly. The rack assembly is driven by a drive component, causing it to move horizontally and longitudinally in a linear motion. This rotates the sterile cryovial caps along a first direction, ultimately tightening each cap onto its corresponding sterile cryovial. Then, the opening and closing assembly is moved to its reset position.

[0008] If it is necessary to loosen the caps of the sterile cryovials containing samples, the drive assembly drives the rack and pinion assembly to rotate the caps in the opposite direction to the first direction, thereby loosening each cap. Then, the opening and closing assembly is moved to reset the opening and closing assembly.

[0009] This system enables the batch opening or closing of sterile cryovials within one minute, a tenfold increase in efficiency compared to the approximately 10 minutes required to manually open / close 50 cryovials. This significantly improves the speed of capping and opening the same batch of cryovials compared to purely manual operation, enhancing efficiency, achieving aseptic operation, and reducing the risk of cryovial contamination. Attached Figure Description

[0010] To more clearly illustrate the technical solutions in the embodiments of this utility model or the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this utility model. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0011] Figure 1 This is a front view of a batch opening and closing device for sterile cryopreservation tube caps according to an embodiment of the present invention.

[0012] Figure 2 yes Figure 1 A top view of the tightened sterile cryopreservation tube cap (without a transparent top panel 41);

[0013] Figure 3 yes Figure 1 A top view of the unsealed sterile cryopreservation tube (without a transparent top panel 41);

[0014] Figure 4 This is a top view of the control component 6 in an embodiment of the present invention (in which the top plate 41 is visible in the view and the transverse soft steel wire 61 is in a relaxed state).

[0015] Figure 5 This is a top view of the control component 6 in an embodiment of the present invention (in which the top plate 41 is visible and the transverse soft steel wire 61 is in a taut state).

[0016] Figure 6 This is a front view of the fixing component according to an embodiment of the present utility model;

[0017] Figure 7 This is a top view of the fixing component according to an embodiment of the present utility model;

[0018] Figure 8This is a front view of the support leg assembly according to an embodiment of the present utility model;

[0019] Figure 9 This is a top view of an embodiment of the present invention, including the fixing component and the pressure relief hole;

[0020] Figure 10 yes Figure 1 Enlarged front view of section A;

[0021] Figure 11 yes Figure 10 Top view;

[0022] Figure 12 yes Figure 10 The left view.

[0023] The reference numerals in the attached figures are as follows:

[0024] 10. Sterile cryopreservation tube rack; 100. Sterile cryopreservation tube cap;

[0025] 1. Base; 2. Opening / closing assembly; 3. Drive assembly; 4. Upper support base; 5. Fixing assembly; 6. Control assembly; 7. Support leg assembly;

[0026] 11. Pressure relief hole;

[0027] 21. Limiting barrel; 22. Rack and pinion assembly; 23. Mounting frame;

[0028] 31. First ratchet; 32. Second ratchet; 33. Drive structure; 34. Connecting rod;

[0029] 41. Top slab;

[0030] 51. Sphere; 52. Umbrella-shaped blade; 53. Vertical steel wire; 54. Limiting plate;

[0031] 61. Horizontal soft steel wire; 62. Movable connecting rod; 63. Connecting rod guide groove; 64. Toggle switch;

[0032] 71. Outer cylinder; 72. Inner rod; 73. Spring;

[0033] 211. Card slot;

[0034] 221. First rack; 222. Second rack;

[0035] 331. Driving gear; 332. Eccentric driven gear; 333. Gear shifting;

[0036] 641. Pivot point. Detailed Implementation

[0037] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0038] like Figures 1 to 12 As shown in the figure, in conjunction with the embodiments of the present invention, a batch opening and closing device for sterile cryopreservation tube caps is provided, including a base 1 for placing a sterile cryopreservation tube rack 10 and an opening and closing component 2 connected to the base 1 and disposed on the sterile cryopreservation tube rack 10. The sterile cryopreservation tube rack 10 is capable of placing multiple rows and multiple columns of sterile cryopreservation tubes, and each sterile cryopreservation tube has a sterile cryopreservation tube cap 100 for sealing the sterile cryopreservation tube.

[0039] The opening and closing assembly 2 includes a rack and pinion assembly 22 driven by a mechanical structure to engage with the circumferential grooves on the outer wall of each sterile cryopreservation tube cap 100. Each rack and pinion assembly 22 is used to tighten or loosen the corresponding sterile cryopreservation tube cap 100 from the sterile cryopreservation tube.

[0040] The batch opening and closing device for sterile cryopreservation tube caps further includes a drive assembly 3 that drives the rack assembly 22 to rotate the sterile cryopreservation tube cap 100 on the sterile cryopreservation tube to tighten or loosen the sterile cryopreservation tube cap 100.

[0041] After multiple sterile cryovials are loaded with their respective samples, they are placed in the sterile cryovial holders on the sterile cryovial rack 10. The rack assembly 22 engages with the circumferentially knurled outer wall of the corresponding sterile cryovial cap 100. Driven by the drive assembly 3, the rack assembly 22 moves longitudinally, causing the sterile cryovial cap 100 to rotate in the first direction, thus finally tightening each sterile cryovial cap 100 onto its corresponding sterile cryovial. Then, the opening / closing assembly 2 is moved to its reset position.

[0042] If it is necessary to loosen the sterile cryopreservation tube cap 100 on the sterile cryopreservation tube containing the sample, the drive assembly 3 drives the rack and pinion assembly 22, which drives the sterile cryopreservation tube cap 100 to rotate in the opposite direction to the first direction, thereby finally loosening each sterile cryopreservation tube cap 100, and then moving the opening and closing assembly 2, while simultaneously resetting the opening and closing assembly 2.

[0043] This system enables the batch opening or closing of sterile cryovials within one minute, a tenfold increase in efficiency compared to the approximately 10 minutes required to manually open / close 50 cryovials. It significantly improves the capping and opening speed of the same batch of cryovials compared to purely manual operation, enhancing efficiency, achieving aseptic operation, and reducing the risk of cryovial contamination compared to electric equipment.

[0044] Preferably, 50 sterile cryovials are opened or closed simultaneously.

[0045] Preferably, the material is 316L stainless steel. All components are designed to be detachable, facilitating the replacement of consumable parts after sterilization.

[0046] Preferably, the sterile cryovials have multiple longitudinal columns; the batch opening and closing device for the caps of the sterile cryovials further includes an upper support 4, which is movably connected to the base 1, and the upper support 4 has a side wall and a top plate 41 connected to the side wall.

[0047] The opening and closing component 2 includes a mounting frame 23 and multiple sets of longitudinal rack and pinion assemblies 22 arranged in parallel.

[0048] The number of longitudinal columns of the rack assembly 22 is the same as the number of longitudinal columns of the sterile cryopreservation tube. Each longitudinal column of the rack assembly 22 is fixed on the mounting frame 23, and the mounting frame 23 is slidably mounted under the top plate 41.

[0049] The opening and closing assembly 2 also includes a limiting barrel 21 for limiting the position of each of the sterile cryopreservation tube caps 100. The limiting barrel 21 is connected below the top plate 41. The limiting barrel 21 has multiple longitudinal columns. The side wall of the limiting barrel 21 is symmetrically provided with slots 211. Each set of rack and pinion assemblies 22 can be matched and engaged with the circumferential straight lines on the outer wall of the corresponding sterile cryopreservation tube cap 100 through the slots 211.

[0050] Each rack assembly 22 includes a first rack 221 and a second rack 222 arranged with opposite teeth. The first rack 221 and the second rack 222 are respectively fixed on the mounting frame 23. A longitudinal row of limiting barrels 21 is disposed between the first rack 221 and the second rack 222 of the rack assembly 22. By horizontally moving the mounting frame 23, the first rack 221 of the same group can simultaneously engage with the circumferential straight-line matching of the outer wall of the sterile cryopreservation tube cap 100 in the limiting barrel 21 through the slot 211 of the same longitudinal row, or by horizontally moving the mounting frame 23, the second rack 222 of the same group can simultaneously engage with the circumferential straight-line matching of the outer wall of the sterile cryopreservation tube cap 100 in the limiting barrel 21 through the slot 211 of the same longitudinal row.

[0051] Preferably, the drive assembly 3 includes a first ratchet 31 and a second ratchet 32, wherein the first ratchet 31 is disposed in the rack assembly 22 in the rightmost longitudinal column, and the second ratchet 32 ​​is disposed in the rack assembly 22 in the leftmost longitudinal column;

[0052] By moving the mounting frame 23, the first ratchet 31, the second ratchet 32, and the first rack 221 in the same longitudinal column can simultaneously engage with the circumferential grooves of the outer wall of the sterile cryopreservation tube cap 100 in the limiting barrel 21 through the slots 211 in the same longitudinal column; or by moving the mounting frame 23 horizontally, the first ratchet 31, the second ratchet 32, and the second rack 222 in the same longitudinal column can simultaneously engage with the circumferential grooves of the outer wall of the sterile cryopreservation tube cap 100 in the limiting barrel 21 through the slots 211 in the same longitudinal column.

[0053] The drive assembly 3 also includes a drive structure 33 that drives the first ratchet 31 to rotate;

[0054] The drive assembly 3 further includes a connecting rod 34 connected to the first ratchet 31 and the second ratchet 32 ​​for synchronous rotation of the first ratchet 31 and the second ratchet 32.

[0055] The drive structure 33 drives the first ratchet 31 to rotate, and drives all the second ratchet 32 ​​to rotate through the connecting rod 34, so that the first ratchet 31 and the second ratchet 32 ​​drive all the first racks 221 to move longitudinally in a straight line at the same time, or drive all the second racks 222 to move longitudinally in a straight line at the same time.

[0056] Preferably, the drive structure 33 includes a gear pair, a paddle 333, and a lever. The gear pair includes a driving gear 331 and an eccentric driven gear 332. The lever is connected to the driving gear 331 for actuating the driving gear 331. One end of the paddle 333 is fixed on the eccentric shaft of the eccentric driven gear 332, and the other end of the paddle 333 rests on the teeth of the first ratchet 31 for actuating the teeth of the first ratchet 31.

[0057] By shifting the lever to move the drive gear 331, the drive gear 331 drives the eccentric driven gear 332 to rotate, which in turn drives the shifting teeth 333. The shifting teeth 333 drive the first ratchet 31 to rotate, and the connecting rod 34 drives all the second ratchet 32 ​​to rotate. This causes the first ratchet 31 and the second ratchet 32 ​​to drive all the first racks 221 to move longitudinally in a straight line at the same time, or to drive all the second racks 222 to move longitudinally in a straight line at the same time, ensuring the consistency of torque in batch operations.

[0058] Preferably, the batch opening and closing device for sterile cryopreservation tube caps further includes a fixing component 5, each fixing component 5 corresponding to one sterile cryopreservation tube cap 100.

[0059] The fixing component 5 includes a sphere 51, umbrella-shaped blades 52 covering the sphere 51 and connected at their upper ends (flexibly) and separated at their lower ends (rigidly), and a vertical steel wire 53 traction on the upper end of the sphere 51. The first end of the vertical steel wire 53 is connected to the upper end of the sphere 51, and the second end of the vertical steel wire 53 passes through the upper ends of multiple umbrella-shaped blades 52 and is movably connected to the upper support base 4. The fixing component 5 enters the limiting barrel 21 through its upper end and is located below the limiting barrel 21, meaning the vertical steel wire 53 passes through the hollow interior of the limiting barrel 21, and the sphere 51 and umbrella-shaped blades 52 are located below the lowest end of the limiting barrel 21. Finally, it can enter the groove at the upper end of the sterile cryopreservation tube cap 100. The multiple umbrella-shaped blades 52 can be flattened during the process of the sphere 51 being pulled upward by the vertical steel wire 53, and the formed outer periphery is stuck below the horizontal edge of the groove. The upper end of the groove has a horizontal edge extending towards the middle, and the unfolded diameter of the umbrella-shaped blades 52 is larger than the inner diameter of the horizontal edge.

[0060] After multiple sterile cryovials have been loaded with their respective samples, they are placed in the sterile cryovial holder on the sterile cryovial rack 10. The opening and closing assembly 2 is moved downwards, and the limiting barrel 21 of the opening and closing assembly 2 is snapped onto the sterile cryovial cap 100. At the same time, the ball 51 and umbrella-shaped blade 52 in a fixing assembly 5 enter the corresponding groove at the upper end of the sterile cryovial cap 100. As the vertical steel wire 53 is pulled upwards by external force, the umbrella-shaped blade 52 can be flattened, and the formed outer periphery is stuck below the horizontal edge of the groove, thereby limiting the sterile cryovial cap 100.

[0061] When the first rack 221 (or the second rack 222) enters the slot 211 on the same side and engages with the circumferential grooves of all the sterile cryovial caps 100, the drive assembly 3 drives the first rack 221 (or the second rack 222) to move linearly. The first rack 221 (or the second rack 222) then drives the sterile cryovial caps 100 to rotate in the first direction, thereby finally tightening each sterile cryovial cap 100 onto the corresponding sterile cryovial. Then, the opening and closing assembly 2 is moved upward to reset the opening and closing assembly 2.

[0062] If it is necessary to loosen the sterile cryopreservation tube cap 100 on the sterile cryopreservation tube containing the sample, the opening and closing component 2 is moved downward. At the same time, the ball 51 and umbrella-shaped blade 52 in a fixing component 5 enter the groove at the upper end of the corresponding sterile cryopreservation tube cap 100. During the process of pulling the vertical steel wire 53 upward by external force, the umbrella-shaped blade 52 can be flattened and the formed outer periphery is stuck below the horizontal edge of the groove, thereby limiting the sterile cryopreservation tube cap 100.

[0063] When the second rack 222 (or the first rack 221) enters the slot 211 on the same side and engages with the circumferential grooves of all the sterile cryopreservation tube caps 100, the second rack 222 (or the first rack 221) is driven by the drive assembly 3. The second rack 222 (or the first rack 221) drives the sterile cryopreservation tube caps 100 to rotate in the opposite direction to the first direction, thereby finally releasing each sterile cryopreservation tube cap 100. Then the opening and closing assembly 2 moves upward to disengage the sterile cryopreservation tube cap 100 from the corresponding sterile cryopreservation tube, while simultaneously resetting the opening and closing assembly 2.

[0064] Preferably, the fixing component 5 further includes a limiting plate 54 disposed on the umbrella-shaped blade 52. The diameter of the limiting plate 54 is smaller than the diameter of the horizontal edge of the groove. The second end of the vertical steel wire 53 passes through the limiting plate 54 and can be movably connected to the upper support base 4. When the vertical steel wire 53 is pulled upward by external force, it can be flattened and the formed outer periphery is locked below the horizontal edge of the groove. The limiting plate 54 can prevent the ball 51 and the umbrella-shaped blade 52 from being pulled off by the vertical steel wire 53.

[0065] Preferably, the batch opening and closing device for sterile cryopreservation tube caps further includes a control component 6 disposed in the upper support 4 to control the fixing component 5. The control component 6 includes multiple horizontally arranged transverse soft steel wires 61, a movable connecting rod 62, and two oppositely arranged connecting rod guide grooves 63.

[0066] The first end of each transverse soft steel wire 61 is fixed on the first side wall of the side wall, and the second end of the transverse soft steel wire 61 is fixed on the movable connecting rod 62. The movable connecting rod 62 is provided on the second side wall opposite to the first side wall, and the connecting rod guide groove 63 is provided on the second side wall. The two ends of the movable connecting rod 62 are respectively slidably provided in one of the connecting rod guide grooves 63.

[0067] Each of the transverse soft steel wires 61 is disposed on the sterile cryopreservation tube caps 100 in a transverse column, and the transverse soft steel wires 61 are disposed above the limiting barrel 21 and below the top plate 41, and correspond to the position of the sterile cryopreservation tube caps 100 in each transverse column, and the second end of each of the vertical steel wires 53 in the transverse column is movably connected to the transverse soft steel wires 61.

[0068] The control component 6 also includes a toggle switch 64 that can switch the transverse soft steel wire 61 between a tensioned state and a slack state. The toggle switch 64 is mounted on the top plate 41 via a fulcrum 641.

[0069] By placing the transverse soft steel wire 61 in a taut state, the upper end of the vertical steel wire 53 is adjusted to a position on the transverse soft steel wire 61, thereby tautening the vertical steel wire 53. During the upward pulling of the vertical steel wire 53, the umbrella-shaped blade 52 can be flattened and the formed periphery is locked below the horizontal edge of the groove, thereby limiting the aseptic cryopreservation tube cap 100.

[0070] If the sphere 51 and the umbrella-shaped blade 52 are disengaged from the groove, the transverse soft steel wire 61 needs to be placed in a relaxed state. Then the umbrella-shaped blade 52 falls, and the sterile cryopreservation tube cap 100 can be peeled off.

[0071] Preferably, the toggle switch 64 includes a first movable end and a latch that holds the first movable end. The first movable end is connected to the movable connecting rod 62. When the first movable end is latched on the latch, the toggle switch 64 is closed. The movable connecting rod 62 moves to the far end of the connecting rod guide groove 63, so that all the transverse soft steel wires 61 are in a taut state. The far end of the connecting rod guide groove 63 is away from the second side wall.

[0072] When the first movable end disengages from the latch, the toggle switch 64 is opened, and the movable connecting rod 62 moves to the proximal end of the connecting rod guide groove 63, causing the transverse soft steel wire 61 to be in a relaxed state, wherein the proximal end of the connecting rod guide groove 63 is close to the second side wall.

[0073] Preferably, the batch opening and closing device for sterile cryopreservation tube caps further includes four sets of support leg assemblies 7. Each set of support leg assemblies 7 includes an outer cylinder 71 vertically arranged and connected to the base 1, an inner rod 72 slidably disposed in the outer cylinder 71 and connected to the upper support seat 4, and a spring 73 disposed in the outer cylinder 71. The first end of the spring 73 is fixed to the base 1, and the second end of the spring 73 extends and retracts freely and contacts the bottom of the inner rod 72.

[0074] When the opening and closing assembly 2 is moved downward, it is necessary to press the opening and closing assembly 2 downward with both hands, and the inner rod 72 presses the spring 73 downward, so that the opening and closing assembly 2 moves downward.

[0075] When the opening and closing assembly 2 is moved upward, release both hands. Under the action of the spring 73's rebound force, the inner rod 72 is moved upward, causing the opening and closing assembly 2 to move upward.

[0076] Preferably, the base 1 has a pressure relief hole 11, which is located on the base 1 inside each of the outer cylinders 71. When the opening and closing assembly 2 is moved downward, it is necessary to press the opening and closing assembly 2 downward with both hands. The inner rod 72 presses down on the spring 73, and at the same time, the air pressed downward in the outer cylinder 71 is discharged from the pressure relief hole 11. This prevents the air pressure in the outer cylinder 71 from increasing and thus increasing the force of pressing down with both hands, thereby providing better comfort for the user.

[0077] It should be understood that in the above detailed description, various features are combined together in a single embodiment to simplify this disclosure. This approach to disclosure should not be interpreted as reflecting an intention that embodiments of the claimed subject matter require more features than are explicitly stated in each claim. Rather, as reflected in the appended claims, the present invention is in a state with fewer features than all of the disclosed individual embodiments. Therefore, the appended claims are hereby explicitly incorporated into the detailed description, wherein each claim stands alone as a preferred embodiment of the present invention.

[0078] The disclosed embodiments have been described above to enable any person skilled in the art to implement or use this invention. Various modifications to these embodiments will be apparent to those skilled in the art, and the general principles defined herein can be applied to other embodiments without departing from the spirit and scope of this disclosure. Therefore, this disclosure is not limited to the embodiments given herein, but is consistent with the widest scope of the principles and novel features disclosed in this application.

[0079] The foregoing description includes examples of one or more embodiments. It is certainly impossible to describe all possible combinations of components or methods in order to describe the above embodiments, but those skilled in the art will recognize that further combinations and arrangements of the various embodiments are possible. Therefore, the embodiments described herein are intended to cover all such changes, modifications, and variations that fall within the scope of the appended claims. Furthermore, the term "comprising" as used in the specification or claims is interpreted in a manner similar to the term "including," as interpreted when used as a conjunction in the claims. Additionally, the use of any term "or" in the specification of the claims is intended to mean "non-exclusive or."

[0080] The specific embodiments described above further illustrate the purpose, technical solution, and beneficial effects of this utility model. It should be understood that the above description is only a specific embodiment of this utility model and is not intended to limit the scope of protection of this utility model. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of this utility model should be included within the scope of protection of this utility model.

Claims

1. A bulk opening and closing device for sterile cryogenic tube caps, characterized in that, The system includes a base (1) for placing a sterile cryopreservation tube rack (10) and an opening and closing assembly (2) connected to the base (1) and disposed on the sterile cryopreservation tube rack (10). The sterile cryopreservation tube rack (10) is capable of holding multiple vertical columns and multiple horizontal columns of sterile cryopreservation tubes, and each sterile cryopreservation tube has a sterile cryopreservation tube cap (100) at its opening. The opening and closing assembly (2) includes a rack assembly (22) that is mechanically driven to engage with the circumferential grooves on the outer wall of each sterile cryopreservation tube cap (100). The batch opening and closing device for sterile cryopreservation tube caps further includes a drive assembly (3) that drives the rack assembly (22) to rotate the sterile cryopreservation tube cap (100) on the sterile cryopreservation tube to tighten or loosen the sterile cryopreservation tube cap (100).

2. The batch opening and closing device for sterile cryogenic tube caps according to claim 1, characterized in that It also includes an upper support (4), which is movably connected to the base (1), and the upper support (4) has a side wall and a top plate (41) connected to the side wall. The opening and closing component (2) includes a mounting frame (23) and multiple sets of longitudinal racks (22) arranged in parallel. The number of longitudinal columns of the rack assembly (22) is the same as the number of longitudinal columns of the sterile cryopreservation tube. Each longitudinal column of the rack assembly (22) is fixed on the mounting frame (23), which is slidably mounted under the top plate (41). The opening and closing assembly (2) further includes a limiting barrel (21) for limiting each of the sterile cryopreservation tube caps (100). The limiting barrel (21) is connected below the top plate (41). The limiting barrel (21) has multiple longitudinal columns. The side wall of the limiting barrel (21) is symmetrically provided with slots (211). Each set of rack and pinion assemblies (22) can engage with the circumferential grooves of the outer wall of the corresponding sterile cryopreservation tube cap (100) through the slots (211). Each rack assembly (22) includes a first rack (221) and a second rack (222) arranged with opposite teeth. The first rack (221) and the second rack (222) are respectively fixed on the mounting frame (23). A longitudinal column of the limiting barrel (21) is disposed between the first rack (221) and the second rack (222) of the rack assembly (22). By horizontally moving the mounting frame (23), the first rack (221) of the same group can simultaneously engage with the circumferential straight-line matching of the outer wall of the sterile cryopreservation tube cap (100) in the limiting barrel (21) through the slot (211) of the same longitudinal column. Alternatively, by horizontally moving the mounting frame (23), the second rack (222) of the same group can simultaneously engage with the circumferential straight-line matching of the outer wall of the sterile cryopreservation tube cap (100) in the limiting barrel (21) through the slot (211) of the same longitudinal column.

3. The batch opening and closing device for sterile cryogenic tube caps according to claim 2, characterized in that The drive assembly (3) includes a first ratchet (31) and a second ratchet (32), the first ratchet (31) being located in the rack assembly (22) in the rightmost longitudinal column, and the second ratchet (32) being located in the rack assembly (22) in the leftmost longitudinal column; By horizontally moving the mounting frame (23), the first ratchet (31), the second ratchet (32), and the first rack (221) in the same longitudinal column can simultaneously engage with the circumferential grooves of the outer wall of the sterile cryopreservation tube cap (100) in the limiting barrel (21) through the slot (211) in the same longitudinal column; or by horizontally moving the mounting frame (23), the first ratchet (31), the second ratchet (32), and the second rack (222) in the same longitudinal column can simultaneously engage with the circumferential grooves of the outer wall of the sterile cryopreservation tube cap (100) in the limiting barrel (21) through the slot (211) in the same longitudinal column. The drive assembly (3) further includes a drive structure (33) that drives the first ratchet (31) to rotate. The drive assembly (3) further includes a connecting rod (34) connected to the first ratchet (31) and the second ratchet (32) for synchronous rotation of the first ratchet (31) and the second ratchet (32).

4. The batch opening and closing device for aseptic cryogenic tube caps according to claim 3, characterized in that The drive structure (33) includes a gear pair, a paddle (333) and a lever. The gear pair includes a driving gear (331) and an eccentric driven gear (332). The lever is connected to the driving gear (331) for paddle action. One end of the paddle (333) is fixed on the eccentric shaft of the eccentric driven gear (332), and the other end of the paddle (333) rests on the teeth of the first ratchet (31).

5. The batch opening and closing device for aseptic cryogenic tube caps according to claim 2, characterized in that, It also includes a fixing component (5), each of the fixing components (5) corresponding to one of the sterile cryopreservation tube caps (100); The fixing component (5) includes a sphere (51), umbrella-shaped blades (52) covering the sphere (51) with their upper ends connected and their lower ends separated, and a vertical steel wire (53) pulling on the upper end of the sphere (51). The first end of the vertical steel wire (53) is connected to the upper end of the sphere (51), and the second end of the vertical steel wire (53) passes through the upper end of the multiple umbrella-shaped blades (52) and can be movably connected to the upper support seat (4). After the fixing component (5) enters the groove at the upper end of the sterile cryopreservation tube cap (100), the multiple umbrella-shaped blades (52) can be flattened during the process of the sphere (51) being pulled upward by the vertical steel wire (53), and the outer periphery of the umbrella-shaped blades (52) is stuck below the horizontal edge of the groove. The upper end of the groove has a horizontal edge extending towards the middle, and the unfolded diameter of the umbrella-shaped blades (52) is greater than the inner diameter of the horizontal edge.

6. The batch opening and closing device for sterile cryogenic tube caps according to claim 5, characterized in that The fixing component (5) also includes a limiting plate (54) disposed on the umbrella-shaped blade (52). The diameter of the limiting plate (54) is smaller than the diameter of the horizontal edge of the groove. The second end of the vertical steel wire (53) passes through the limiting plate (54) and can be movably connected to the upper support seat (4).

7. The batch opening and closing device for sterile cryopreservation tube caps according to claim 5, characterized in that, It also includes a control component (6) located in the upper support (4) to control the fixing component (5). The control component (6) includes multiple horizontally arranged transverse soft steel wires (61), a movable connecting rod (62), and two oppositely arranged connecting rod guide grooves (63). The first end of each transverse soft steel wire (61) is fixed on the first side wall of the side wall, and the second end of the transverse soft steel wire (61) is fixed on the movable connecting rod (62). The movable connecting rod (62) is located on the second side wall opposite to the first side wall. The connecting rod guide groove (63) is located on the second side wall. The two ends of the movable connecting rod (62) are respectively slidably located in one of the connecting rod guide grooves (63). Each of the transverse soft steel wires (61) is disposed on a transverse row of sterile cryopreservation tube caps (100), and the second end of each of the vertical steel wires (53) located below the transverse soft steel wires (61) is movably connected to the transverse soft steel wires (61). The control component (6) also includes a toggle switch (64) that can switch the transverse soft steel wire (61) between a tensioned state and a slack state. The toggle switch (64) is mounted on the top plate (41) via a fulcrum (641).

8. The batch opening and closing device for sterile cryogenic tube caps according to claim 7, characterized in that The toggle switch (64) includes a first movable end and a buckle that holds the first movable end in place. The first movable end is connected to the movable connecting rod (62). When the first movable end is held in place by the buckle, the toggle switch (64) is closed. The movable connecting rod (62) moves to the far end of the connecting rod guide groove (63) so that all the transverse soft steel wires (61) are in a taut state. The far end of the connecting rod guide groove (63) is away from the second side wall. When the first movable end disengages from the latch, the toggle switch (64) is opened, and the movable connecting rod (62) moves to the proximal end of the connecting rod guide groove (63), causing the transverse soft steel wire (61) to be in a relaxed state, wherein the proximal end of the connecting rod guide groove (63) is close to the second side wall.

9. The batch opening and closing device for aseptic cryogenic tube caps according to claim 2, characterized in that, It also includes four sets of support leg assemblies (7). Each set of support leg assemblies (7) includes an outer cylinder (71) that is vertically arranged and connected to the base (1), an inner rod (72) that is slidably arranged in the outer cylinder (71) and connected to the upper support seat (4), and a spring (73) arranged in the outer cylinder (71). The first end of the spring (73) is fixed to the base (1), and the second end of the spring (73) is freely extended and retracted and contacts the bottom of the inner rod (72).

10. The batch opening and closing device for sterile cryogenic tube caps according to claim 9, characterized in that The base (1) has a pressure relief hole (11) located on the base (1) inside each of the outer cylinders (71).

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