A non-toxic teaching aid for liquid chromatography experiments

By using amorphous silica-filled high aspect ratio liquid chromatography columns and food-grade reagents, the problems of harmful solvent use and long separation times in liquid chromatography teaching have been solved, achieving safe and rapid chromatographic separation and reusable columns, thus improving the practicality of teaching.

CN224457519UActive Publication Date: 2026-07-03BEIJING ORIENDA INSTR CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
BEIJING ORIENDA INSTR CO LTD
Filing Date
2025-10-11
Publication Date
2026-07-03

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Abstract

This invention discloses a non-toxic liquid chromatography teaching aid, comprising a medium-pressure liquid chromatography column with an aspect ratio of not less than 10, activated amorphous silica gel, a syringe, a pre-dispensed mixture of target compounds, and pre-dispensed food-grade citric acid. The pre-dispensed mixture of target compounds is a mixture of carmine, tartrazine, and brilliant blue. This invention does not use harmful solvents or reagents, and the separation time is significantly reduced to less than 3 minutes. Furthermore, the chromatographic column used as a teaching aid can be reused multiple times. The actual separation cost is only pure water and food coloring solution, greatly improving the feasibility of chromatography teaching experiments.
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