A self-weight sealing type biological sample slide

Abstract

The utility model discloses a kind of self-weight sealing biological sample slides, including carrier plate and bottom plate, the bottom plate is connected in carrier plate bottom by screw;Multiple sample glass structure is installed on bottom plate, the sample glass structure includes glass slide assembly and cover glass assembly, chamber is sealed between the glass slide assembly and cover glass assembly;The glass slide assembly includes glass slide frame and glass slide glass, and the cover glass assembly includes cover glass frame and cover glass glass;First sealing groove is set on the inner step surface of the glass slide frame, and second sealing groove and third sealing groove are respectively set on the boss of the glass slide frame and outer wing plate;First, second, third silica gel sealing ring are respectively arranged in the first, second, third sealing groove;The cover glass frame is buckled on the glass slide frame in the way of self-weight, and the cover glass frame is respectively provided with the boss portion matched with first, second, third sealing groove.

Description

Technical Field

[0001] This utility model relates to the field of microscope slide technology, and more specifically, to a self-weight sealed biological sample microscope slide. Background Technology

[0002] Traditional biological sample slides typically consist of a set of glass slides and a set of coverslips. The biological sample is immersed in the cavity between the coverslip and the glass slide. When it is necessary to observe or compare multiple sets of biological samples simultaneously, in order to improve the convenience of biological sample observation, some biological sample slides have multiple sets of glass slides and coverslips on a set of base plates to hold biological samples of different volumes.

[0003] In existing technologies, because the coverslip rests solely on the slide by its own weight, its poor sealing allows liquids soaking the biological sample to easily evaporate along the gap between the slide frame and the coverslip frame, preventing the biological sample slide from being preserved for extended periods. Consequently, when observing multiple samples on the substrate, some biological samples are susceptible to observational problems due to liquid evaporation. Furthermore, the existing method of bonding the coverslip glass to the coverlip frame makes it impossible to replace contaminated coverslip glass, rendering the entire coverslip assembly disposable, resulting in material waste and increased costs. Utility Model Content

[0004] The purpose of this invention is to provide a weight-sealed biological sample slide to solve the problems mentioned in the background art.

[0005] The objective of this utility model is achieved through the following technical solution:

[0006] A self-sealing biological sample slide includes a carrier plate and a base plate, the base plate being connected to the bottom of the carrier plate by screws; multiple sample glass structures are mounted on the base plate located within the cavity of the carrier plate, each sample glass structure including a slide assembly and a coverslip assembly covering the slide assembly, with a sealed chamber for containing biological samples between the slide assembly and the coverslip assembly; each slide assembly includes a slide frame and a slide glass disposed on the slide frame, and each coverslip assembly includes a coverslip glass. The slide frame and the cover glass mounted on the cover glass frame; a first sealing groove is formed on the inner stepped surface of the slide frame near the cover glass, and a second sealing groove and a third sealing groove are formed on the protrusion and outer wing plate of the slide frame, respectively; a first, second, and third silicone sealing ring are respectively provided in the first, second, and third sealing grooves; the cover glass frame is fastened to the slide frame by its own weight, and the cover glass frame is provided with protrusions that cooperate with the first, second, and third sealing grooves.

[0007] Furthermore, a perforated pressure plate for pressing and sealing the cover glass is installed on the cover glass frame by a clamping screw, and a fourth silicone sealing ring is provided between the pressure plate and the cover glass.

[0008] Furthermore, multiple magnetic positioning posts are provided on the surface of the base plate located within the inner cavity of the carrier plate; the magnetic positioning posts cooperate with the positioning holes provided on the outer wing plate of the glass slide frame.

[0009] Furthermore, multiple spacers for isolating the sample glass structure are provided on the surface of the base plate located in the inner cavity of the carrier plate.

[0010] Furthermore, multiple loading and unloading ports for loading and unloading glass slide assemblies are provided on both the upper and lower sides of the inner cavity of the carrier plate.

[0011] The beneficial effects of this utility model are as follows: Based on the prior art, this utility model creates a first sealing groove on the inner step surface of the slide frame near the slide glass, and creates a second and a third sealing groove on the protrusion and outer wing plate of the slide frame, respectively. Simultaneously, first, second, and third silicone sealing rings are respectively provided in the first, second, and third sealing grooves, and the coverslip frame is provided with protrusions that cooperate with the first, second, and third sealing grooves. By adopting the above three-layer labyrinthine sealing structure, the overall sealing effect of the chamber is achieved. To enable the replacement of the coverslip glass, this utility model also installs a perforated pressure plate on the coverslip frame using clamping screws to press and seal the coverslip glass. This allows the coverslip glass to be placed inside the coverslip frame without adhesive bonding, facilitating its replacement. Furthermore, a fourth silicone sealing ring is provided between the pressure plate and the coverslip glass to prevent the sample solution from overflowing from the top of the coverslip glass and to prevent evaporation of the sample solution after replacement. Attached Figure Description

[0012] Figure 1 This is a structural diagram of the present invention.

[0013] Figure 2 for Figure 1 Structural diagram of the mid-base plate.

[0014] Figure 3 for Figure 1 Diagram showing the connection structure between the middle slide assembly and the cover slide assembly.

[0015] Figure 4 for Figure 3 A sectional view along the AA direction.

[0016] The attached diagram lists the components represented by each number as follows:

[0017] 1-Carrier plate, 2-Slide frame, 3-Cover slide frame, 4-Installation port, 5-Spacer block, 6-Magnetic limiting post, 7-Base plate, 8-Screw, 9-Limiting hole, 10-Hollowed pressure plate, 11-Pressure screw, 12-Cover slide glass, 13-Slide glass, 14-Cavity, 15-Third silicone sealing ring, 16-Second silicone sealing ring, 17-First silicone sealing ring, 18-Fourth silicone sealing ring, 19-Boss. Detailed Implementation

[0018] The principles and features of this utility model are described below. The examples given are only for explaining this utility model and are not intended to limit the scope of this utility model. Example

[0019] Reference Figure 1-4 As shown, the self-weight sealed biological sample slide of this embodiment includes a carrier plate 1 and a base plate 7. The base plate 7 is connected to the bottom of the carrier plate by screws 8. Three sample glass structures of different capacities are installed on the base plate located in the inner cavity of the carrier plate 1. Each sample glass structure includes a slide assembly and a coverslip assembly covering the slide assembly. A chamber 14 for accommodating biological samples is sealed between the slide assembly and the coverslip assembly. The slide assembly includes a slide frame 2 and a slide glass 13 disposed on the slide frame. The coverslip assembly includes a coverslip frame 3 and a coverslip frame 4. The cover glass 12 is provided; a first sealing groove is provided on the inner stepped surface of the slide frame near the slide glass 13; a second sealing groove and a third sealing groove are provided on the protrusion 19 of the slide frame and the outer wing plate, respectively; a first, second, and third silicone sealing ring 17, 16, and 15 are respectively provided in the first, second, and third sealing grooves; the cover glass frame 3 is fastened to the slide frame by its own weight, and the cover glass frame is provided with protrusions that cooperate with the first, second, and third sealing grooves; this embodiment achieves the overall sealing effect of the chamber by adopting the above three-layer labyrinth-style sealing structure. Example

[0020] refer to Figure 3-4 Based on Embodiment 1, in order to achieve the replaceability of the cover glass, a perforated pressure plate 10 for pressing and sealing the cover glass 12 is installed on the cover glass frame 3 by a clamping screw 11. A fourth silicone sealing ring 18 is provided between the pressure plate and the cover glass. This embodiment can realize that the cover glass does not need to be set in the cover glass frame by adhesive, which facilitates its replacement. At the same time, the fourth silicone sealing ring is provided between the pressure plate and the cover glass to prevent the sample solution from overflowing from the top of the cover glass and to prevent the evaporation of the sample solution after the cover glass is replaced. Example

[0021] Based on Embodiment 1, in order to achieve the effect of fixing the slide assembly on the base plate, multiple magnetic positioning posts 6 are provided on the surface of the base plate 7 located in the inner cavity of the carrier plate; the magnetic positioning posts 6 cooperate with the positioning holes 9 provided on the outer wing plate of the slide frame 2; four partitions 5 for isolating the sample glass structure are provided on the surface of the base plate 7 located in the inner cavity of the carrier plate; eight openings 4 for picking up and putting down the slide assembly are provided on both the upper and lower sides of the inner cavity of the carrier plate 1; this embodiment realizes the positioning of the entire slide assembly and cover glass assembly with the base plate, and it is easy to pick up and put down manually during the experiment, making the arrangement of the slide assembly more uniform and beautiful.

[0022] The above description is only a preferred embodiment of the present utility model, but the protection scope of the present utility model is not limited thereto. Any equivalent substitutions or changes made by those skilled in the art within the technical scope disclosed in the present utility model, based on the technical solution and the inventive concept of the present utility model, should be included within the protection scope of the present utility model.

Claims

1. A self-weight sealed biological sample slide, comprising a carrier plate (1) and a base plate (7), wherein the base plate (7) is connected to the bottom of the carrier plate by screws (8); a plurality of sample glass structures are mounted on the base plate located in the inner cavity of the carrier plate (1), wherein the sample glass structure comprises a slide assembly and a cover glass assembly covering the slide assembly, wherein a chamber (14) for accommodating biological samples is sealed between the slide assembly and the cover glass assembly; the slide assembly comprises a slide frame (2) and a slide glass (13) disposed on the slide frame, and the cover glass assembly comprises a cover glass frame (3) and a cover glass (12) disposed on the cover glass frame; characterized in that: A first sealing groove is provided on the inner step surface of the slide frame near the slide glass (13). A second sealing groove and a third sealing groove are provided on the boss (19) of the slide frame and on the outer wing plate, respectively. First, second, and third silicone sealing rings (17, 16, and 15) are respectively provided in the first, second, and third sealing grooves. The cover glass frame (3) is fastened to the slide frame by its own weight, and the cover glass frame is provided with protrusions that cooperate with the first, second, and third sealing grooves.

2. The weight-sealed biological sample slide according to claim 1, characterized in that, A perforated pressure plate (10) for pressing and sealing the cover glass (12) is installed on the cover glass frame (3) by a pressure screw (11), and a fourth silicone sealing ring (18) is provided between the pressure plate and the cover glass.

3. The self-weight sealed biological sample slide according to claim 1, characterized in that, Multiple magnetic positioning posts (6) are provided on the surface of the base plate (7) located in the inner cavity of the carrier plate; the magnetic positioning posts (6) cooperate with the positioning holes (9) provided on the outer wing plate of the glass slide frame (2).

4. The weight-sealed biological sample slide according to claim 1, characterized in that, Multiple spacers (5) for isolating the sample glass structure are provided on the plate surface of the base plate (7) located in the inner cavity of the carrier plate.

5. The weight-sealed biological sample slide according to claim 1, characterized in that, Multiple pick-up and drop-out ports (4) for picking up and dropping glass slide assemblies are provided on both the upper and lower sides of the inner cavity of the carrier plate (1).

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