A portable injection device for gene therapy

Abstract

The utility model discloses a portable injection device for gene therapy relates to medical instrument technical field, including the limiting sleeve, the top fixed mounting of limiting sleeve has the top cover, the bottom fixed mounting of top cover has the piston rod, the bottom fixed connection of piston rod has the rubber piston, the outside of rubber piston is equipped with the needle cylinder. The setting of portable injection device for gene therapy limiting sleeve can carry out effective protection to the piston rod and the reset spring in, and the top cover of limiting sleeve top can better with hand carry out the adhesion, to guarantee the comfort of use, the setting of telescopic positioning mechanism can make the cooperation needle cylinder telescopic in the inside of limiting sleeve, is favorable to automatic extraction to the liquid medicine when stretching out, and is favorable to reducing the length of whole when contracting, has improved portable injection device for gene therapy use convenience and storage convenience.

Description

Technical Field

[0001] This utility model relates to the field of medical device technology, specifically a portable injection device for gene therapy. Background Technology

[0002] Gene therapy, as a highly promising treatment method, has made significant progress in recent years, bringing new hope for the treatment of many intractable diseases. By introducing exogenous genes into target cells to correct or compensate for diseases caused by gene defects and abnormalities, it demonstrates a precision and effectiveness that traditional treatments cannot match. In the actual operation of gene therapy, the injection device, as a key drug delivery tool, has a crucial impact on the treatment effect due to its performance and characteristics. However, existing gene therapy injection devices still have certain shortcomings in their use.

[0003] A puncture and injection device for cell genetic engineering, as proposed in application number CN202222125831.4, includes a syringe, a push rod inside the syringe, a connecting post at the center of the bottom of the syringe, a needle sleeve and a needle connected to the bottom of the syringe via the connecting post, an adjusting thread on the outer surface of the syringe near the bottom, a rotating sleeve corresponding to the adjusting thread on the outer surface of the syringe, and a telescopic protective sleeve at the bottom of the rotating sleeve. In actual use, this puncture and injection device for cell genetic engineering retracts the telescopic protective sleeve by pressing down on the syringe, and then presses the push rod to inject after the needle contacts the injection target. The extension length of the telescopic protective sleeve can also be adjusted by adjusting the rotating sleeve to adapt to injection targets of different thicknesses. However, this puncture and injection device for cell genetic engineering requires manual operation for both drug extraction and injection, reducing the convenience and labor-saving effect of operation. At the same time, the design of the syringe and the telescopic protective sleeve results in an excessively long overall length of the device, reducing its ease of storage.

[0004] Therefore, we propose a portable injection device for gene therapy to address the problems mentioned above. Utility Model Content

[0005] The purpose of this invention is to provide a portable injection device for gene therapy, so as to solve the problems mentioned in the background art that make it inconvenient to simplify the injection process to improve labor-saving effect and reduce the convenience of storage.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a portable injection device for gene therapy, comprising a limiting sleeve.

[0007] The top of the limiting sleeve is fixedly installed with a top cover, the bottom of the top cover is fixedly installed with a piston rod, the bottom end of the piston rod is fixedly connected with a rubber piston, a syringe is sleeved on the outside of the rubber piston, and the outside of the syringe is symmetrically marked with graduations.

[0008] A telescopic positioning mechanism is connected between the syringe and the limiting sleeve;

[0009] A connecting seat is fixedly installed at the bottom end of the syringe, a docking seat is connected to the outer ring of the connecting seat, and a needle is fixedly installed at the bottom end of the docking seat.

[0010] The syringe is equipped with a detachable protective mechanism at its bottom.

[0011] Preferably, the outer ring of the rubber piston is in close contact with the inner wall of the syringe, and the connecting seat is threadedly connected to the mating seat.

[0012] The design of the above structure allows the rubber piston to form a tight piston injection mechanism with the syringe, and the threaded connection between the connecting seat and the docking seat facilitates the disassembly and replacement of the needle, which helps to improve the cleanliness and safety of the portable injection device for gene therapy during injection.

[0013] Preferably, the telescopic positioning mechanism includes a movable plate fixedly installed on the top of the syringe, pull plates symmetrically installed on the outer ring of the movable plate, a return spring sleeved on the outer ring of the piston rod between the movable plate and the top cover, symmetrically opened sliding grooves inside the limiting sleeve, a rotating groove opened at the top of the sliding groove, and a locking groove opened at the end of the rotating groove away from the sliding groove.

[0014] Preferably, the movable plate forms a telescopic structure with the top cover via a return spring, and the pull plate forms a movable engaging structure with the slide groove, the rotating groove, and the locking groove.

[0015] The above-described structure facilitates the manual retraction and automatic ejection of the syringe through the control of the telescopic positioning mechanism. This allows for the extraction of medication during automatic ejection and the injection of medication during manual retraction. Furthermore, it enables the syringe to be retracted and positioned inside the limiting sleeve after injection, thereby reducing the storage length and improving portability.

[0016] Preferably, the detachable protective mechanism includes a rubber retaining ring fixedly installed on the outer ring of the bottom end of the syringe, the outer ring of the rubber retaining ring being fitted with a protective sleeve, and the inner side of the top end of the protective sleeve being provided with an interlocking groove.

[0017] Preferably, two sets of rubber retaining rings are provided at the bottom end of the syringe, and two sets of fitting grooves are provided on the inner side of the top end of the protective sleeve, and the rubber retaining rings are movably engaged with the fitting grooves.

[0018] The above-described structure design facilitates the sealing connection between the docking seat and the bottom of the syringe via a detachable protective mechanism after the docking seat and needle are disassembled. This seals and protects the opening of the docking seat, preventing bacterial growth and improving the protective effect and safety of the portable injection device for gene therapy.

[0019] Compared with the prior art, the beneficial effects of this utility model are: the portable injection device for gene therapy;

[0020] 1. The limiting sleeve effectively protects the internal piston rod and return spring, while the top cover of the limiting sleeve fits better in the hand, ensuring comfort during use. At the same time, the telescopic positioning mechanism allows the syringe to extend and retract inside the limiting sleeve, which is beneficial for automatic extraction of the drug when extended and for reducing the overall length when retracted, thus improving the ease of use and storage of this portable injection device for gene therapy.

[0021] 2. The threaded connection between the docking seat and the connecting seat facilitates easy replacement of the needle, which is beneficial for installing the needle during injection and removing the needle during storage. After disassembly, the opening of the connecting seat can be effectively sealed and protected by the detachable protective mechanism, which improves the protective effect of this portable injection device for gene therapy. Attached Figure Description

[0022] Figure 1 This is a side view of the unfolded structure of this utility model;

[0023] Figure 2 This is a side view schematic diagram of the storage structure of this utility model;

[0024] Figure 3 This is a side view of the exploded structure of this utility model;

[0025] Figure 4 This is a schematic diagram of the distribution structure of the piston rod and return spring of this utility model;

[0026] Figure 5 This is a side view of the protective sleeve and its connection structure with the syringe of this utility model.

[0027] In the diagram: 1. Limiting sleeve; 2. Top cover; 3. Piston rod; 4. Rubber piston; 5. Syringe; 6. Scale; 7. Movable plate; 8. Pull plate; 9. Return spring; 10. Slide groove; 11. Rotary groove; 12. Snap groove; 13. Connecting seat; 14. Docking seat; 15. Needle; 16. Rubber retaining ring; 17. Protective sleeve; 18. Fitting groove. Detailed Implementation

[0028] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0029] Please see Figure 1-5 This utility model provides a technical solution: a portable injection device for gene therapy, including a limiting sleeve 1, a top cover 2 fixedly installed on the top of the limiting sleeve 1, a piston rod 3 fixedly installed on the bottom of the top cover 2, a rubber piston 4 fixedly connected to the bottom end of the piston rod 3, a syringe 5 sleeved on the outside of the rubber piston 4, the outer ring of the rubber piston 4 tightly fitting the inner wall of the syringe 5, symmetrically marked with scales 6 on the outer side of the syringe 5, a connecting seat 13 fixedly installed at the bottom end of the syringe 5, a docking seat 14 connected to the outer ring of the connecting seat 13, the connecting seat 13 and the docking seat 14 being threadedly connected, and a needle 15 fixedly installed at the bottom end of the docking seat 14;

[0030] The design of the above structure allows the fixedly installed piston rod 3 and rubber piston 4 to retract relative to the syringe 5 when the syringe 5 pops out from inside the limiting sleeve 1. At this time, the gene therapy drug can be actively drawn through the connecting seat 13, docking seat 14 and needle 15. When the syringe 5 retracts into the limiting sleeve 1, the fixedly installed piston rod 3 and rubber piston 4 advance relative to the syringe 5, thereby allowing the drawn gene therapy drug to be discharged through the connecting seat 13, docking seat 14 and needle 15 for injection. The top cover 2 can improve hand comfort during the injection process.

[0031] A telescopic positioning mechanism is connected between the syringe 5 and the limiting sleeve 1. The telescopic positioning mechanism includes a movable plate 7 fixedly installed at the top of the syringe 5. A pull plate 8 is symmetrically installed on the outer ring of the movable plate 7. A return spring 9 is sleeved on the outer ring of the piston rod 3 between the movable plate 7 and the top cover 2. The movable plate 7 and the top cover 2 form a telescopic structure through the return spring 9. A sliding groove 10 is symmetrically opened inside the limiting sleeve 1. A rotating groove 11 is opened at the top of the sliding groove 10. A locking groove 12 is opened at the end of the rotating groove 11 away from the sliding groove 10. The pull plate 8, the sliding groove 10, the rotating groove 11 and the locking groove 12 form a movable locking structure.

[0032] The design of the above results allows the movable plate 7 to extend and retract inside the limiting sleeve 1 by pulling the pull plate 8 and pushing the movable plate 7 by the return spring 9. At this time, the pull plate 8 will also slide inside the slide groove 10. When the movable plate 7 and the syringe 5 retract upward inside the limiting sleeve 1, the pull plate 8 will be aligned with the rotating groove 11 at the top of the slide groove 10. At this time, by rotating the pull plate 8, the movable plate 7 and the syringe 5, the pull plate 8 can be rotated and aligned with the locking groove 12. Then, the pulling force of the pull plate 8 is released. At this time, the elastic force of the return spring 9 can push the pull plate 8 to engage with the locking groove 12, and can retract and position the syringe 5 inside the limiting sleeve 1 to reduce the storage length. During injection, the control and rotation of the pull plate 8, the movable plate 7 and the syringe 5 can make the pull plate 8 aligned with the slide groove 10. Then, the elastic force of the return spring 9 can push the movable plate 7 and the syringe 5 to automatically pop out, and the gene therapy drug can be extracted during the pop-out process.

[0033] The bottom of the syringe 5 is equipped with a detachable protective mechanism, which includes a rubber retaining ring 16 fixedly installed on the outer ring of the bottom end of the syringe 5. Two sets of rubber retaining rings 16 are provided at the bottom end of the syringe 5. A protective sleeve 17 is sleeved on the outer ring of the rubber retaining ring 16. A fitting groove 18 is opened on the inner side of the top end of the protective sleeve 17. Two sets of fitting grooves 18 are opened on the inner side of the top end of the protective sleeve 17. The rubber retaining ring 16 is movably engaged with the fitting groove 18.

[0034] The above-described structure allows the docking seat 14 and needle 15 to be separated from the connecting seat 13. By fitting the protective sleeve 17 onto the lower end of the syringe 5, the rubber retaining ring 16 can deform and elastically engage with the fitting groove 18. At this time, the protective sleeve 17 provides a sealed protection for the connecting seat 13, preventing bacterial growth. In use, a strong pull on the protective sleeve 17 can separate the fitting groove 18 from the rubber retaining ring 16, thus disassembling the protective sleeve 17. At this time, the connecting seat 13 and the docking seat 14 can be threaded together to install the needle 15.

[0035] This completes a series of tasks. The contents not described in detail in this specification are existing technologies known to those skilled in the art.

[0036] Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A portable injection device for gene therapy, comprising a limiting sleeve (1), characterized in that: The top of the limiting sleeve (1) is fixedly installed with a top cover (2), the bottom of the top cover (2) is fixedly installed with a piston rod (3), the bottom end of the piston rod (3) is fixedly connected with a rubber piston (4), the outside of the rubber piston (4) is fitted with a syringe (5), and the outside of the syringe (5) is symmetrically provided with scales (6). A telescopic positioning mechanism is connected between the syringe (5) and the limiting sleeve (1); The syringe (5) is fixedly installed with a connecting seat (13) at the bottom end. The outer ring of the connecting seat (13) is connected with a docking seat (14). The bottom end of the docking seat (14) is fixedly installed with a needle (15). The syringe (5) is equipped with a detachable protective mechanism at its bottom.

2. The portable injection device for gene therapy according to claim 1, characterized in that: The outer ring of the rubber piston (4) is tightly fitted to the inner wall of the syringe (5), and the connecting seat (13) is threadedly connected to the docking seat (14).

3. The portable injection device for gene therapy according to claim 1, characterized in that: The telescopic positioning mechanism includes a movable plate (7) fixedly installed on the top of the syringe (5). A pull plate (8) is symmetrically installed on the outer ring of the movable plate (7). A return spring (9) is sleeved on the outer ring of the piston rod (3) between the movable plate (7) and the top cover (2). A sliding groove (10) is symmetrically opened inside the limiting sleeve (1). A rotating groove (11) is opened at the top of the sliding groove (10). A retaining groove (12) is opened at the end of the rotating groove (11) away from the sliding groove (10).

4. A portable injection device for gene therapy according to claim 3, characterized in that: The movable plate (7) forms a telescopic structure with the top cover (2) through the return spring (9), and the pull plate (8) forms a movable locking structure with the slide groove (10), the rotating groove (11) and the slot (12).

5. A portable injection device for gene therapy according to claim 1, characterized in that: The detachable protective mechanism includes a rubber retaining ring (16) fixedly installed on the outer ring of the bottom end of the syringe (5). The outer ring of the rubber retaining ring (16) is fitted with a protective sleeve (17), and the inner side of the top end of the protective sleeve (17) is provided with a fitting groove (18).

6. A portable injection device for gene therapy according to claim 5, characterized in that: Two sets of rubber retaining rings (16) are provided at the bottom end of the syringe (5), and two sets of fitting grooves (18) are provided on the inner side of the top end of the protective sleeve (17). The rubber retaining rings (16) and fitting grooves (18) are movably engaged and connected.

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