A staining instrument for hematoxylin and eosin solution concentration determination and adjustment

Abstract

The utility model discloses a kind of dyeing instruments of hematoxylin and eosin solution concentration determination and adjustment, including the shell body of upper end open mouth, chain clamping structure is equipped in the top of shell body;Several liquid storage barrels are equipped with interval in shell body and the top of the liquid storage barrel is open, the bottom of the liquid storage barrel for storing hematoxylin and eosin solution and the liquid storage barrel for storing fresh water located in the right side of the liquid storage barrel are each equipped with drip device;Concentration detection structure is also equipped in shell body below drip device;It also includes concentration adjustment structure being equipped in the bottom of each liquid storage barrel, and the concentration adjustment structure, chain clamping structure, drip device, concentration detection structure are all with the controller of being equipped on the side wall of shell body electrical connection.The utility model has the advantages of being able to determine and adjust hematoxylin and eosin solution concentration to ensure dyeing quality and reduce waste, effectively improve work efficiency and pathological report accuracy to assist surgeon to formulate next operation plan in time.

Claims

1. A staining instrument for measuring and adjusting the concentration of hematoxylin and eosin solutions, comprising an outer shell (1) with an open upper end, and a chain clamping structure (2) for clamping external glass slides provided on the top of the outer shell (1); characterized in that: A plurality of storage tanks (3) for storing corresponding liquids are provided at intervals inside the outer shell (1), and the top of the storage tank (3) is open to allow external glass slides to be inserted for immersion and staining treatment. A dropper (4) is provided at the bottom of the storage tank (3) for storing hematoxylin and eosin solutions and the storage tank (3) for storing water located on the right side of the storage tank (3). A concentration detection structure (5) is also provided on the outer shell (1) below the dropper (4). A concentration adjustment structure (6) is also provided at the bottom of each storage tank (3), and the concentration adjustment structure (6), chain clamping structure (2), dropper (4), and concentration detection structure (5) are all electrically connected to a controller (7) provided on one side wall of the outer shell (1).

2. The staining instrument for hematoxylin and eosin concentration determination and adjustment according to claim 1, characterized in that: The chain clamping structure (2) includes a chain support (21) on the top of the outer shell (1). Gears (22) are provided on both sides of the bottom of the upper end of the chain support (21), and one of the gears (22) is connected to the output shaft of a drive motor (23) mounted on the chain support (21). A rolling chain (24) is provided between the two gears (22). A slide clamp (26) for clamping external glass slides is provided on the outer wall of the rolling chain (24) through an electric push rod (25) for inserting into the corresponding liquid storage tank (3) for soaking and staining treatment. The drive motor (23) and the electric push rod (25) are both electrically connected to the controller (7).

3. The staining instrument for hematoxylin and eosin concentration determination and adjustment of claim 1, wherein: The dripper (4) includes a storage tank (3) for storing hematoxylin and eosin solutions and a drip opening (41) located on the bottom of the storage tank (3) on the right side for storing water. A drip electric valve (42) electrically connected to the controller (7) is provided on the drip opening (41), and a drip nozzle (43) is provided at the outlet end of the drip electric valve (42).

4. The staining instrument for hematoxylin and eosin concentration determination and adjustment according to claim 3, characterized in that: The concentration detection structure (5) includes a photochemical detection device (51) on one side wall of the outer shell (1), and rollers (52) on both sides directly below the dropper (43) on the outer shell (1). One of the rollers (52) is connected to the output shaft of a drive motor (53) mounted on the outer shell (1). A conveyor belt (54) is sleeved between the two rollers (52). A test strip (55) is provided at the top of the conveyor belt (54) for receiving the liquid delivered by the corresponding dropper (43) and moving it to the bottom of the photochemical detection device (51) to perform the concentration determination of hematoxylin and eosin solution. The photochemical detection device (51) and the drive motor (53) are both electrically connected to the controller (7).

5. The staining instrument for hematoxylin and eosin concentration determination and adjustment according to claim 4, characterized in that: The concentration adjustment structure (6) includes a liquid output pipe (61) and a liquid input pipe (62) provided on both sides of the bottom of each liquid storage tank (3) for cooperating with each other to adjust the liquid concentration inside the liquid storage tank (3). The liquid output pipe (61) and the liquid input pipe (62) are both electrically connected to the controller (7).

6. The staining instrument for hematoxylin and eosin concentration determination and adjustment according to claim 5, characterized in that: The liquid output pipeline (61) includes an output pipe (611) located at the bottom front of the corresponding liquid storage tank (3). One end of the output pipe (611) away from the liquid storage tank (3) is connected to a waste liquid tank (613) via an output pump (612) electrically connected to the controller (7). An output electric valve (614) electrically connected to the controller (7) is also provided on the output pipe (611).

7. The staining instrument for hematoxylin and eosin concentration determination and adjustment according to claim 6, characterized in that: The liquid input pipeline (62) includes an input pipe (621) located at the bottom rear side of the corresponding liquid storage tank (3). The end of the input pipe (621) away from the liquid storage tank (3) is connected to the liquid storage tank (623) via an input pump (622) electrically connected to the controller (7). An input electric valve (624) electrically connected to the controller (7) is also provided on the input pipe (621).

8. The staining instrument for hematoxylin and eosin concentration determination and adjustment according to any one of claims 1 to 7, characterized in that: At least eleven storage tanks (3) are provided, arranged from right to left in the outer shell (1) for storing hematoxylin solution, water, saturated lithium carbonate solution, water, eosin solution, water, 75% ethanol, 80% ethanol, 95% ethanol, 100% ethanol, and xylene, respectively; and above each of the storage tanks (3) storing 75% ethanol, 80% ethanol, 95% ethanol, 100% ethanol, and xylene, there is a drain cover (8) that reduces evaporation while ensuring that an external glass slide can be inserted.

9. The staining apparatus for determining and adjusting the concentration of hematoxylin and eosin solutions according to claim 4, characterized in that: Each of the liquid storage tanks (3) is provided with a water level sensor (9) that is electrically connected to the controller (7) for warning of the highest and lowest water levels; a protective shell (10) is also provided on the front side wall of the outer shell (1) via an external self-locking hinge to prevent external personnel from accidentally touching the conveyor belt (54) and causing interference to the concentration measurement.

10. The staining apparatus for determining and adjusting the concentration of hematoxylin and eosin solutions according to claim 9, characterized in that: The photochemical detection device (51) is any one of a visible spectrophotometer, a fluorescence spectrophotometer, a high-performance liquid chromatograph, or an atomic absorption spectrometer.

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