A dry blood spot collection tube with convenient control of blood volume

Abstract

The utility model discloses a dry blood stain collection tube convenient to control blood sampling amount, including sampling tube, the sampling tube has the liquid storage part for accommodating blood and the liquid outlet end of communication with this liquid storage part, still include the bottom cover of with sampling tube lower extreme connection, the utility model discloses a dry blood stain collection tube convenient to control blood sampling amount through setting up quantitative collection unit, utilizes the cooperation of quantitative tube and collection cavity to realize the accurate quantitative of blood, effectively avoided the problem of too much or insufficient blood sampling amount caused by the liquid taking of extrusion type in the prior art, guarantee the consistency of dry blood stain sample amount and the reliability of detection result, with the axial movable cooperation of bottom cover and sampling tube, can switch the closed and open state of liquid outlet end flexibly, both the sealing protection during storage, and can efficiently complete the blood sampling operation, the combination design of push -move component and steel needle, capillary channel has realized the convenient transfer of quantitative blood to filter paper piece, and simple operation can avoid blood overflow.

Description

Technical Field

[0001] This utility model relates to the field of dried blood spot collection technology, specifically to a dried blood spot collection tube that facilitates control of blood collection volume. Background Technology

[0002] Dried blood spot samples are formed by collecting whole blood samples on special filter paper and allowing the blood to dry. Due to their good biostability and safety, as well as their ease of storage and transportation, they have become an important sample form in blood testing.

[0003] To achieve effective collection of dried blood spot samples, existing technologies have disclosed relevant patents, such as CN202223140925.5, which discloses a dried blood spot sampling device. This device involves placing a positioning cylinder into a positioning groove on a dried blood spot sampling book, and then manually pressing the soft rubber tube on the squeezing section to allow blood to drip through the dropper onto the sampling filter paper in the positioning groove, achieving precise dripping and uniform wetting of the blood. After collecting a suitable number of blood spots, patient information and sampling time can be recorded in the information filling area. Once the blood spots have coagulated and formed dried blood spots, the cover and sampling page can be folded in half for protection. When using dried blood spots, simply pull the filter paper to remove the sampling filter paper with dried blood spots from the positioning groove, eliminating the need for cutting and greatly simplifying the sampling and usage process. However, this device uses a squeezing method involving a soft rubber tube and a hard plastic arc blade (similar to the structure of an ink-absorbing pen, such as the ink-absorbing pen with a screw-down holder as described in CN200420017635.4). In actual operation, when the hard plastic arc blade squeezes the soft rubber tube, the amount of blood squeezed out of the tube is difficult to control precisely. This defect may result in excessive blood dripping, causing over-wetting of the filter paper or even blood overflow, affecting the accuracy of sample collection; or insufficient dripping, failing to meet the sample volume required for testing, thus affecting the reliability of subsequent test results and causing inconvenience to the standardized collection of dried blood spot samples. Utility Model Content

[0004] The purpose of this invention is to provide a dried blood spot collection tube that allows for convenient control of blood collection volume, thereby solving the problem in the prior art where the blood collection volume is difficult to control precisely, which affects the accuracy of sample collection and the reliability of subsequent testing, and realizing the standardized and precise collection of dried blood spot samples.

[0005] This utility model provides the following technical solution: a dried blood spot collection tube for convenient control of blood collection volume, including a sampling tube, the sampling tube having a liquid storage part for containing blood and a liquid outlet end communicating with the liquid storage part, and also including a bottom cover connected to the lower end of the sampling tube, the bottom cover being provided with a quantitative collection unit for collecting the blood discharged from the liquid outlet end;

[0006] The quantitative collection unit includes a collection chamber for receiving blood discharged from the outlet end, and a quantitative tube located at the center of the collection chamber and communicating with the collection chamber. The upper end of the quantitative tube is higher than any part of the collection chamber, and the end of the quantitative tube away from the collection chamber is provided with a breakable isolation structure.

[0007] The bottom cover is axially movable at the lower end of the sampling tube, so that the lower end of the liquid outlet can enter or leave the interior of the metering tube.

[0008] The bottom cover is also movably equipped with a pushing component, which is fixedly connected to a steel needle that coincides with the axis of the metering tube. The steel needle has a capillary channel fixed inside, which penetrates the bottom surface of the pushing component. When the pushing component moves relative to the bottom cover toward the metering tube, the steel needle can pierce the isolation structure and allow the upper end of the capillary channel to enter the interior of the metering tube.

[0009] Compared with the prior art, the beneficial effects of this utility model are as follows: This utility model provides a dried blood spot collection tube that facilitates control of blood collection volume. By setting up a quantitative collection unit, the cooperation between the quantitative tube and the collection chamber achieves precise quantitative blood collection, effectively avoiding the problem of excessive or insufficient blood collection caused by squeeze-type liquid extraction in the prior art, ensuring the consistency of dried blood spot sample volume and the reliability of test results; with the axial movable cooperation between the bottom cover and the sampling tube, the closed and open states of the liquid outlet can be flexibly switched, which is convenient for sealing and protection during storage and can efficiently complete the blood collection operation; the combined design of the pushing component, steel needle, and capillary channel realizes the convenient transfer of quantitative blood to the filter paper, which is simple to operate and can avoid blood spillage, significantly improving the standardization and operational efficiency of dried blood spot sample collection. Attached Figure Description

[0010] Figure 1 This is a cross-sectional structural diagram of the present invention.

[0011] Figure 2 This is a three-dimensional structural diagram of the present invention.

[0012] Figure 3 This is a three-dimensional structural diagram of the bottom cover of the collection tube of this utility model.

[0013] Figure 4 This is a schematic diagram of the bottom cover of the collection tube of this utility model from a bottom view. Detailed Implementation

[0014] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0015] Please see Figure 1-4 This utility model discloses a dried blood spot collection tube for convenient control of blood collection volume, including a sampling tube 8. The sampling tube 8 has a liquid storage part 10 for containing blood and a liquid outlet 11 communicating with the liquid storage part 10. The liquid storage part 10 is a deformable flexible tube body. By squeezing the flexible tube body, the internal blood can be discharged from the liquid outlet 11. The side of the sampling tube 8 is provided with an operation opening 9, and a movable protective arc plate 1 is movably connected to the operation opening 9. In use, blood is collected into the sampling tube 8, the movable protective arc plate 1 is opened, and the blood can be squeezed through the operation opening 9 to drip onto the surface of the dried blood spot filter paper added at the liquid outlet 11. The above structure of this utility model is similar to the structure of existing dried blood spot collection tubes, such as the dried blood spot sampling device disclosed in CN202223140925.5, which will not be described in detail here.

[0016] It is understandable that when the flexible tube is squeezed directly, several drops of blood can be squeezed out at once, resulting in inconsistent blood volume in the dried blood spot sample. The main improvement of this utility model is that it also includes a bottom cover 12 connected to the lower end of the sampling tube 8. The upper end of the bottom cover 12 is open and can be fitted onto the outside of the lower end of the sampling tube 8. The bottom cover 12 is provided with a quantitative collection unit for collecting the blood discharged from the liquid outlet 11.

[0017] The quantitative collection unit includes a collection chamber 3 for receiving blood discharged from the outlet 11, and a quantitative tube 4 located at the center of the collection chamber 3 and connected to the collection chamber 3. The upper end of the quantitative tube 4 is higher than any part of the collection chamber 3, and the end of the quantitative tube 4 away from the collection chamber 3 is provided with a breakable isolation structure 14. With the above structure, when the flexible tube of the liquid storage part 10 is squeezed, blood will drip into the quantitative tube 4 directly below through the outlet 11. Excess blood will automatically overflow into the collection chamber 3 after filling the quantitative tube 4, thereby realizing quantitative collection.

[0018] The bottom cover 12 can move axially at the lower end of the sampling tube 8 so that the lower end of the liquid outlet 11 can enter or leave the interior of the metering tube 4. Before making dried blood spots, the bottom cover 12 is placed on the lower end of the sampling tube 8, and the liquid outlet 11 is inserted into the metering tube 4. The metering tube 4 can be made of rubber tubing to seal the lower end of the liquid outlet 11. When making dried blood spots, the bottom cover 12 can be moved downward so that the liquid outlet 11 is moved above the metering tube 4, making it convenient to drip blood into the interior of the metering tube 4.

[0019] In some embodiments, the upper end of the sampling tube 8 is connected to a cap 7, and the cap 7 and the sampling tube 8 can be threaded together, or the cap 7 can be a common bottle stopper structure.

[0020] To facilitate the transfer of the quantified blood from the metering tube 4 to the surface of the dried blood stain filter paper, a pushing component 13 is movably mounted on the bottom cover 12. The pushing component 13 is fixedly connected to a steel needle 5 that coincides with the axis of the metering tube 4. A capillary channel 6 is fixed inside the steel needle 5. The lower end of the capillary channel 6 penetrates the bottom surface of the pushing component 13, and the upper end of the capillary channel 6 penetrates the top of the steel needle 5. When the pushing component 13 moves relative to the bottom cover 12 toward the metering tube 4, the steel needle 5 can pierce the isolation structure 14 and allow the upper end of the capillary channel 6 to enter the interior of the metering tube 4. After the quantification is completed, the sampling tube 8 can be held in hand, the bottom cover 12 placed on the surface of the dried blood stain filter paper, and then the sampling tube 8 can be pressed down to move the pushing component 13 upward into the bottom cover 12, thereby pushing the steel needle 5 and the capillary channel 6 to pierce the isolation structure 14 at the bottom of the metering tube 4. In this way, the capillary channel 6 can draw the blood from the metering tube 4 to the surface of the dried blood stain filter paper.

[0021] The isolation structure 14 can be a rubber structure integrally formed with the metering tube 4. The steel needle 5 is similar to the needle of a syringe. When the needle pierces the rubber stopper of the medicine bottle, the medicine can be drawn from the medicine bottle. The principle of the steel ball 5 piercing the isolation structure 14 in this utility model is similar.

[0022] In some embodiments, the longitudinal section of the collection chamber 3 is inverted V-shaped, and the quantitative tube 4 and the collection chamber 3 are integrally formed. The collection chamber 3 can also be other shapes, as long as the blood in the quantitative tube 4 can overflow and flow into the collection chamber 3 after it is full. In order to facilitate observation of the internal situation, the bottom cover 12 is preferably a transparent structure.

[0023] The lower end of the sampling tube 8 has an external thread 2 on its outer wall. The upper end of the bottom cover 12 is threaded to the external thread 2. It can be understood that when performing quantitative analysis, the bottom cover 12 can be rotated downwards to move the bottom cover 12 towards the lower end of the sampling tube 8. However, it is not necessary to completely separate the bottom cover 12 from the sampling tube 8. It is only necessary to move the lower end of the liquid outlet 11 out of the quantitative tube 4.

[0024] A peelable film 15 is attached to the bottom surface of the pusher component 13 to prevent the capillary channel 6 from being contaminated by dust.

[0025] The bottom of the bottom cover 12 has a through hole 16, and the pushing member 13 is movably disposed in the through hole 16. The pushing mechanism 13 can be a cylindrical structure, and its side is damped by the inner wall of the through hole 16, that is, it is limited by friction.

[0026] The working principle of this novel dried blood spot collection tube, which facilitates control of blood collection volume, is as follows:

[0027] In the initial state, the bottom cover 12 cooperates with the sampling tube 8 to insert the discharge end 11 into the quantitative tube 4 to achieve a seal. The storage part 10 is used to collect blood. When making dried blood spots, the bottom cover 12 is moved axially to make the discharge end 11 detach from the quantitative tube 4. The flexible storage part 10 of the sampling tube 8 is squeezed, and blood drips into the quantitative tube 4 through the discharge end 11. Excess blood overflows into the collection chamber 3 to complete the quantification. When transferring blood to the surface of the dried blood spot filter paper, the bottom cover 12 is placed on the filter paper, and the sampling tube 8 is pressed to move the pushing member 13 upward. The isolation structure 14 at the bottom of the quantitative tube 4 is pierced by the steel needle 5, and the blood in the quantitative tube 4 is guided to the surface of the filter paper by the capillary channel 6, finally forming a standard dried blood spot sample.

[0028] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A dried blood spot collection tube for convenient control of blood collection volume, comprising a sampling tube, the sampling tube having a reservoir for containing blood and an outlet communicating with the reservoir, characterized in that: It also includes a bottom cover connected to the lower end of the sampling tube, and the bottom cover is provided with a quantitative collection unit for collecting the blood discharged from the liquid outlet. The quantitative collection unit includes a collection chamber for receiving blood discharged from the outlet end, and a quantitative tube located at the center of the collection chamber and communicating with the collection chamber. The upper end of the quantitative tube is higher than any part of the collection chamber, and the end of the quantitative tube away from the collection chamber is provided with a breakable isolation structure. The bottom cover is axially movable at the lower end of the sampling tube, so that the lower end of the liquid outlet can enter or leave the interior of the metering tube. The bottom cover is also movably equipped with a pushing component, which is fixedly connected to a steel needle that coincides with the axis of the metering tube. The steel needle has a capillary channel fixed inside, which penetrates the bottom surface of the pushing component. When the pushing component moves relative to the bottom cover toward the metering tube, the steel needle can pierce the isolation structure and allow the upper end of the capillary channel to enter the interior of the metering tube.

2. The dried blood spot collection tube according to claim 1, characterized in that: The longitudinal section of the collection chamber is inverted V-shaped, and the metering tube and the collection chamber are integrally formed.

3. The dried blood spot collection tube according to claim 1, characterized in that: The liquid storage section is a deformable flexible tube. By squeezing the flexible tube, the internal blood can be discharged from the outlet. The sampling tube has an operation opening on its side, and the operation opening is movably connected to a movable protective arc plate.

4. The dried blood spot collection tube according to claim 1, characterized in that: The lower outer wall of the sampling tube is provided with external threads, and the upper inner wall of the bottom cover is threadedly engaged with the external threads.

5. The dried blood spot collection tube according to claim 1, characterized in that: The bottom surface of the pushing component is covered with a peelable film.

6. The dried blood spot collection tube according to claim 1, characterized in that: The bottom of the cover has a through hole, and the pushing component is movably disposed within the through hole.

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