A pathological section staining device

By setting pressing plates and through grooves on the glass slide to form a recess for storing dye, and using a vibrating motor to achieve uniform distribution of the dye, the problem of excessive dye use in drip dyeing automatic dyeing machines is solved, and the utilization rate of dye and dyeing effect are improved.

CN224552858UActive Publication Date: 2026-07-24THE FIRST AFFILIATED HOSPITAL OF HAINAN MEDICAL UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
THE FIRST AFFILIATED HOSPITAL OF HAINAN MEDICAL UNIV
Filing Date
2025-06-04
Publication Date
2026-07-24

AI Technical Summary

Technical Problem

Automatic drip dyeing machines require excessive dye usage to ensure uniform dye coverage, leading to resource waste and low utilization rates.

Method used

By setting a pressing plate and a through groove on the glass slide, a groove is formed to store the dye. Combined with a vibration motor, the dye is evenly distributed, reducing the amount of dye used.

Benefits of technology

This improved the utilization rate of dyeing agents, ensured the uniformity of dyeing results, and reduced resource waste.

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Abstract

The utility model discloses a pathological section glass staining device, including host computer, the upper end of host computer is equipped with the working groove, be equipped with the object table in the working groove, the object table top from left to right equal interval installs glass slide frame in proper order, and the glass slide frame from front to back equal interval has placed object slide, the top of object table is equipped with the motion platform, and the lower extreme of motion platform is equipped with the liquid outlet subassembly and the cleaning subassembly, and be equipped with the restriction mechanism on the motion platform, and the restriction mechanism includes telescopic motor and presss from both sides, and the upper end of telescopic motor is connected in the motion platform, and presss from both sides and is connected in the lower extreme of motion platform, and presss from both sides on the upper end is equipped with the through groove corresponding with object slide middle part, and the left side in the working groove is equipped with the cleaning assembly for cleaning presss from both sides. The utility model discloses through in the dyeing, presss from both sides and presses in object slide's middle part, forms the recess through the through groove and object slide, and the dyeing agent is stored temporarily, and a small amount of dyeing agent can guarantee the dyeing effect, improves the utilization of dyeing agent.
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Description

Technical Field

[0001] This utility model relates to the field of slide staining technology, and in particular to a slide staining device for pathology. Background Technology

[0002] In the field of pathological diagnosis, slide staining is a core pretreatment step in histological and cytological analysis. In recent years, drop-staining automated staining machines have gradually replaced traditional immersion staining equipment as the mainstream due to their advantages such as standardized operation, high programmability, and low risk of cross-contamination. This type of equipment uses a high-precision nozzle to directly drop staining reagents (such as hematoxylin, eosin, antibody solutions, etc.) onto the surface of a horizontally placed glass slide, which then spreads naturally to cover the sample area based on the surface tension of the liquid.

[0003] Although the drop staining machine significantly improves the consistency of staining, its technical architecture has a key bottleneck: in order to ensure the uniformity of staining coverage, excessive dye reagent is often required. The excess reagent flows away along the edge of the slide, resulting in serious waste of resources and low utilization rate. Utility Model Content

[0004] The purpose of this invention is to provide a pathology slide staining device. By pressing a pressure plate into the middle of a glass slide, a groove is formed between the pressure plate and the glass slide to temporarily store the staining agent. A small amount of staining agent is sufficient to ensure the staining effect and improve the utilization rate of the staining agent.

[0005] The above-mentioned technical objective of this utility model is achieved through the following technical solution:

[0006] A pathology slide staining device includes a main unit with a working groove at its upper end. A stage is located within the working groove. Slide holders are installed on the stage at equal intervals from left to right. Slides are placed on the slide holders at equal intervals from front to back. A motion platform is located above the stage. A liquid dispensing component and a cleaning component are located at the lower end of the motion platform. A limiting mechanism is provided on the motion platform, including a telescopic motor and a pressing plate. The upper end of the telescopic motor is connected to the motion platform, and the pressing plate is connected to the lower end of the motion platform. A through groove corresponding to the center of the slide is formed on the pressing plate. A cleaning component for cleaning the pressing plate is located on the left side of the working groove.

[0007] By adopting the above technical solution, during staining, the pressing slide is pressed onto the glass slide, and the through groove forms a groove on the glass slide to store the staining agent, thereby reducing the amount of staining agent used during staining.

[0008] A further configuration of this utility model is as follows: the motion platform includes a moving mechanism, a support arm, and a moving host. The moving mechanism is located inside the host. The support arm is arranged in a front-to-back orientation. The rear end of the support arm is connected to the moving mechanism. The moving mechanism is used to drive the support arm to move left and right. The moving host is mounted on the support arm and moves back and forth on the support arm. The liquid dispensing component and the cleaning component are both located at the lower end of the moving host.

[0009] By adopting the above technical solution, the liquid dispensing component and the cleaning component can move back and forth and left and right.

[0010] A further feature of this invention is that: two telescopic motors are respectively installed on the front and rear ends of the support arm; the pressing plate is installed on the lower end of the telescopic motor; the front and rear ends of the pressing plate are respectively installed on the lower ends of the two telescopic motors; multiple through slots are provided and evenly distributed from front to back; and the multiple through slots correspond one-to-one with each glass slide on the slide holder.

[0011] By adopting the above technical solution, the limiting mechanism is installed on the support arm, which facilitates the movement of the motion platform to move the limiting mechanism left and right.

[0012] A further feature of this invention is that the limiting mechanism further includes a vibration motor and pressing rings. The vibration motor is installed on the left and right sides of the pressing plate, and multiple pressing rings are provided and installed one-to-one at the lower end of the through groove.

[0013] By employing the above technical solution, the vibrating motor drives the pressing plate to vibrate, allowing the dye to be distributed quickly and evenly. The pressing ring reduces the contact between the pressing plate and the glass slide, ensuring a tight seal between them.

[0014] A further configuration of this utility model is as follows: the cleaning assembly includes a top plate, a side plate, an upper nozzle, and a lower nozzle. The top plate is horizontally disposed on the left side wall of the working trough, the side plate is vertically disposed on the right side of the top plate, the upper nozzle and the lower nozzle are disposed below the top plate, the lower nozzle is disposed below the upper nozzle, the upper nozzle is inclined downward, and the lower nozzle is inclined upward.

[0015] By adopting the above technical solution, the top plate and side plate are used to shield splashing water droplets, while the upper nozzle and lower nozzle are used to rinse the pressing plate and pressing ring.

[0016] A further feature of this invention is that the glass slide has a circular marking ring in the middle.

[0017] By adopting the above technical solution, the range of sample smearing is limited, avoiding direct pressure of the pressing ring onto the sample and causing contamination.

[0018] A further feature of this invention is that the front end of the main unit is provided with a control panel, and the liquid dispensing component, cleaning component, telescopic motor, moving mechanism, moving main unit and vibration motor are all electrically connected to the control panel.

[0019] By adopting the above technical solution, it is convenient to control the coordinated operation of various electronic components.

[0020] In summary, this utility model has the following beneficial effects:

[0021] Firstly, this utility model involves pressing a pressing plate onto the center of a glass slide during the staining process. The plate forms a groove with the glass slide through a through-groove, temporarily storing the staining agent. A small amount of staining agent is sufficient to ensure the staining effect, thus improving the utilization rate of the staining agent.

[0022] Secondly, the vibrating motor in this invention drives the pressing sheet and the glass slide to vibrate, allowing the dye to spread quickly and evenly, thus ensuring the dyeing effect.

[0023] Thirdly, the glass slide in this invention is provided with an identification ring to limit the placement range of the sample and prevent the pressing ring on the pressing slide from contacting the sample and causing contamination. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0025] Figure 2 This is a cross-sectional view of the present invention;

[0026] Figure 3 This is a cross-sectional view of the groove in this utility model;

[0027] Figure 4 This is a schematic diagram of the structure of the glass slide holder in this utility model;

[0028] Figure 5 This is a structural schematic diagram of the cleaning component and the liquid dispensing component in this utility model.

[0029] In the diagram: 1. Main unit; 11. Working trough; 2. Stage; 3. Slide holder; 4. Slide; 41. Identifier ring; 5. Motion platform; 51. Moving mechanism; 52. Support arm; 53. Moving main unit; 6. Restriction mechanism; 61. Telescopic motor; 62. Pressing plate; 63. Through groove; 64. Vibration motor; 65. Pressing ring; 7. Cleaning assembly; 8. Liquid dispensing assembly; 9. Washing assembly; 91. Top plate; 92. Side plate; 93. Upper nozzle; 94. Lower nozzle; 10. Control panel. Detailed Implementation

[0030] The present invention will be further described in detail below with reference to the accompanying drawings.

[0031] In the description of this utility model, it should be understood that the terms "upper", "lower", "left", "right", "front", "rear", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this utility model.

[0032] Furthermore, terms such as "horizontal" and "vertical" do not imply that components must be absolutely horizontal or suspended, but rather that they can be slightly tilted. For example, "horizontal" simply means that its direction is more horizontal than "vertical," and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0033] In the description of this utility model, it should also be noted that, unless otherwise explicitly specified and limited, the terms "set up," "connected," and "linked" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, a direct connection, or an indirect connection through an intermediate medium; or they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model according to the specific circumstances.

[0034] Example: A pathology slide staining device, such as... Figures 1 to 5 As shown, the system includes a main unit 1, with a working slot 11 at its upper end. A stage 2 is located within the working slot 11, and slide holders 3 are mounted on the stage 2 at equal intervals from left to right. The main unit 1, stage 2, and slide holders 3 are all existing technologies and will not be described in detail. Slides 4 are placed at equal intervals from front to back on the slide holders 3. A motion platform 5 is located above the stage 2, and a liquid dispensing component 8 and a cleaning component 9 are located at the lower end of the motion platform 5. The liquid dispensing component 8 is used to add staining agent to the slides 4, and the cleaning component 9 is used to clean the staining agent and liquid from the sample. Both are existing technologies and will not be described in detail. The motion platform 5 includes a moving mechanism 51, a support arm 52, and a moving host 531. The moving mechanism 51 is located inside the host 1. The support arm 52 is arranged facing forward and backward, with its rear end connected to the moving mechanism 51. The moving mechanism 51 drives the support arm 52 to move left and right. The moving host 531 is mounted on the support arm 52 and moves back and forth on the support arm 52. The liquid dispensing component 8 and the cleaning component 9 are both located at the lower end of the moving host 531. The moving mechanism 51 and the moving host 531 can realize the left and right and forward and backward movement of the liquid dispensing component 8 and the cleaning component 9. Of course, vertical movement can also be added, but these are all prior art.

[0035] The motion platform 5 is equipped with a limiting mechanism 6, which includes a telescopic motor 61 and a pressing plate 62. The upper end of the telescopic motor 61 is connected to the motion platform 5, and the pressing plate 62 is connected to the lower end of the motion platform 5. The pressing plate 62 has a through groove 63 corresponding to the middle of the glass slide 4. A cleaning component 7 for cleaning the pressing plate 62 is provided on the left side of the working groove 11. By pressing the pressing plate 62 downward with the telescopic motor 61, the pressing plate 62 is made to stick to the glass slide 4. The through groove 63 and the glass slide 4 form a groove, which limits the diffusion of the dye and reduces the use of dye.

[0036] Two telescopic motors 61 are respectively installed on the front and rear ends of the support arm 52. A pressing plate 62 is installed at the lower end of the telescopic motor 61, with its front and rear ends respectively installed at the lower ends of the two telescopic motors 61. Multiple through slots 63 are provided, evenly spaced from front to back, and each through slot 63 corresponds one-to-one with each glass slide 4 on the slide holder 3. A limiting mechanism 6 is installed on the support arm 52 to press down the glass slides 4 in the same row, facilitating uniform processing.

[0037] The limiting mechanism 6 also includes a vibration motor 64 and pressing rings 65. The vibration motor 64 is installed on the left and right sides of the pressing plate 62, and multiple pressing rings 65 are installed one-to-one at the lower end of the through groove 63. The vibration motor 64 allows the staining agent to be quickly and evenly distributed in the groove, ensuring the staining effect. The pressing rings 65 reduce contact with the glass slide 4, avoiding contact with the sample and causing contamination.

[0038] The cleaning component 7 includes a top plate 91, a side plate 92, an upper nozzle 93, and a lower nozzle 94. The top plate 91 is horizontally positioned on the left side wall of the working trough 11, and the side plate 92 is vertically positioned on the right side of the top plate 91. The upper nozzle 93 and lower nozzle 94 are located below the top plate 91, with the lower nozzle 94 located below the upper nozzle 93. The upper nozzle 93 is tilted downwards, and the lower nozzle 94 is tilted upwards. The upper nozzle 93 and lower nozzle 94 are used to rinse the upper and lower sides of the pressing plate 62. The pressing plate 62 needs to be rinsed after each use to avoid contamination from repeated use. The top plate 91 and side plate 92 are splash-proof during rinsing. The upper nozzle 93 and lower nozzle 94 are connected to a water pump and a water tank for easy cleaning.

[0039] A circular marking ring 41 is provided in the center of the slide 4. This limits the area where the sample is applied and prevents the pressing ring 65 from directly contacting the sample.

[0040] The front end of the main unit 1 is equipped with a control panel 10, and the liquid dispensing component 8, cleaning component 9, telescopic motor 61, moving mechanism 51, moving main unit 531, and vibration motor 64 are all electrically connected to the control panel 10. The control panel 10 is used to control the coordinated operation of the various electronic components.

[0041] Working principle: First, place the slide 4 on the slide holder 3, and then install the slide holder 3 on the stage 2. During staining, the telescopic motor 61 works to press the pressing plate 62 onto the slide 4, and then the staining agent is added. During cleaning, the pressing plate 62 is lifted. After staining the slide 4 on the same slide holder 3, the pressing plate 62 is moved to the bottom of the top plate 91 and the left side of the side plate 92 is cleaned before the next round of staining is carried out.

[0042] This specific embodiment is merely an explanation of the present utility model and is not intended to limit the present utility model. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but as long as they are within the scope of the claims of the present utility model, they are protected by patent law.

Claims

1. A pathology slide staining device, comprising a main unit (1), characterized in that: The upper end of the main unit (1) is provided with a working groove (11), and a stage (2) is provided in the working groove (11). A slide holder (3) is installed on the stage (2) at equal intervals from left to right. A slide (4) is placed on the slide holder (3) at equal intervals from front to back. A motion platform (5) is provided above the stage (2). A liquid dispensing component (8) and a cleaning component (9) are provided at the lower end of the motion platform (5). A limiting mechanism (6) is provided on the motion platform (5). The limiting mechanism (6) includes a telescopic motor (61) and a pressing plate (62). The upper end of the telescopic motor (61) is connected to the motion platform (5). The pressing plate (62) is connected to the lower end of the motion platform (5). A through groove (63) corresponding to the middle of the slide (4) is provided on the pressing plate (62). A cleaning component (7) for cleaning the pressing plate (62) is provided on the left side of the working groove (11).

2. The pathology slide staining device according to claim 1, characterized in that: The motion platform (5) includes a moving mechanism (51), a support arm (52), and a moving host (53). The moving mechanism (51) is located inside the host (1). The support arm (52) is arranged in a front-to-back orientation. The rear end of the support arm (52) is connected to the moving mechanism (51). The moving mechanism (51) is used to drive the support arm (52) to move left and right. The moving host (53) (1) is mounted on the support arm (52). The moving host (53) (53) moves back and forth on the support arm (52). The liquid discharge component (8) and the cleaning component (9) are both located at the lower end of the moving host (53) (1).

3. The pathology slide staining device according to claim 2, characterized in that: The telescopic motor (61) has two parts, which are respectively installed on the front and rear ends of the support arm (52). The pressing piece (62) is installed on the lower end of the telescopic motor (61). The front and rear ends of the pressing piece (62) are respectively installed on the lower ends of the two telescopic motors (61). Multiple through slots (63) are opened and are evenly distributed from front to back. The multiple through slots (63) correspond one-to-one with each glass slide (4) on the slide holder (3).

4. The pathology slide staining device according to claim 3, characterized in that: The limiting mechanism (6) also includes a vibration motor (64) and a pressing ring (65). The vibration motor (64) is installed on the left and right sides of the pressing plate (62), and the pressing ring (65) is provided in multiple and is installed one-to-one at the lower end of the through groove (63).

5. A pathology slide staining device according to claim 4, characterized in that: The cleaning assembly (7) includes a top plate (91), a side plate (92), an upper nozzle (93), and a lower nozzle (94). The top plate (91) is horizontally disposed on the left side wall of the working trough (11), and the side plate (92) is vertically disposed on the right side of the top plate (91). The upper nozzle (93) and the lower nozzle (94) are disposed below the top plate (91), and the lower nozzle (94) is disposed below the upper nozzle (93). The upper nozzle (93) is inclined downward, and the lower nozzle (94) is inclined upward.

6. A pathology slide staining device according to claim 5, characterized in that: The slide (4) has a circular marking ring (41) in the middle.

7. A pathology slide staining device according to claim 6, characterized in that: The front end of the host (1) is provided with a control panel (10), and the liquid dispensing component (8), cleaning component (9), telescopic motor (61), moving mechanism (51), moving host (53) and vibration motor (64) are all electrically connected to the control panel (10).