Viral vectors and their use in adoptive cell therapy
DE202020006214U1Undetermined Publication Date: 2026-09-03IMMATICS US INC
Patent Information
- Application Number
- DE202020006214
- Authority / Receiving Office
- DE · DE
- Patent Type
- Utility models
- Current Assignee / Owner
- Priority Date
- 2019-05-27
- Filing Date
- 2020-05-27
- Publication Date
- 2026-09-03
- Estimated Expiration
- 2030-05-31
Abstract
A nucleic acid sequence comprising: (i) a nucleotide sequence S1 encoding a CD8α polypeptide, (ii) a nucleotide sequence S2 encoding a CD8β polypeptide, (iii) a nucleotide sequence S3 encoding a T-cell receptor (TCR) α polypeptide, and (iv) a nucleotide sequence S4 encoding a TCRβ polypeptide, wherein the nucleotide sequences are arranged in tandem in a 5'-to-3' orientation S2-S1-S4-S3, wherein the CD8α polypeptide comprises an amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO: 11, and the CD8β polypeptide comprises an amino acid sequence that is at least 90% identical to the amino acid sequence of SEQ ID NO: 12.
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Citation Information
Patent Citations
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