Aqueous liquid hand dishwashing composition

Abstract

Aqueous liquid hand dishwashing composition comprising at least 35% by weight water and (i) a surfactant system comprising at least one anionic surfactant (ia) and at least one amine oxide surfactant (ib), (ii) at least one enzyme selected from protease and amylase, (iii) an inorganic sulfur-based antioxidant.

Description

[0001] The present invention relates to an aqueous liquid hand dishwashing composition comprising (i) a surfactant system comprising at least one anionic surfactant and at least one amine oxide cosurfactant, and (ii) at least one enzyme selected from protease and amylase, (iii) an inorganic sulfur-based antioxidant and (iv) optionally an inorganic salt other than (iii). BACKGROUND OF THE INVENTION

[0002] Modern dishwashing detergents contain a surfactant system for soaking and removing stubborn or greasy dirt. For even better performance and easier cleaning for the user, these detergents may contain one or more types of enzymes.

[0003] Protein and carbohydrate soils can be difficult to remove when washing dishes by hand. In automatic dishwashing detergents (ADCs), these soils are removed by adding enzymes such as proteases and amylases to the dry, solid ADCs; however, such enzymes are less stable in aqueous liquid dishwashing detergents. The presence of a surfactant system, particularly one containing anionic surfactants, appears to destabilize the enzymes during storage in an aqueous medium.

[0004] Some surfactants contain traces of inorganic peroxides used in their manufacture. However, even these small amounts of inorganic peroxides can significantly impair the enzymes if they are also present in the cleaning agent.

[0005] Furthermore, for environmental reasons, the use of microplastics such as polyacrylic acid derivatives, which were used in the past as builders and to regulate the viscosity of liquid cleaning systems, is undesirable.

[0006] For manufacturers, it is a challenge to produce highly active, aqueous hand dishwashing detergents that can be precisely dosed and are stable during storage, without adding components that are either undesirable or are now even banned (such as microplastics).

[0007] EP 3 284 805 A1 discloses a hand dishwashing detergent comprising a surfactant system with an anionic surfactant and additionally an amine oxide co-surfactant, a protease and an enzyme stabilizer selected from inorganic potassium salts.

[0008] US 2019 / 0376008 A1 refers to dishwashing detergents comprising a protease and / or amylase, a surfactant system with sodium olefin sulfonate and sodium lauryl ether sulfate as anionic surfactants and at least one amphoteric surfactant, as well as a viscosity regulator.

[0009] DE 10 2017 223 275 A1 describes aqueous liquid cleaning agent compositions containing a synergistic combination of a protease and an amylase, both with a defined sequence, and furthermore a surfactant system comprising an amine oxide, a fatty alcohol ether sulfate and optionally a betaine.

[0010] WO 2014 / 158490 A1 discloses enzyme-containing detergent and pre-wash compositions comprising surfactants, amylase and a reducing agent in a ratio of 1:1 to 3:1, a source of alkalinity, a builder and water, wherein the reducing agent is selected from sodium sulfite, sodium metasulfite and sodium phosphite.

[0011] DE 10 2021 206 648 A1 relates to a hand dishwashing composition comprising surfactants, catalase, and at least one other enzyme. This document explains that the presence of catalase increases the stability of the other enzymes and that potassium salts have a stabilizing effect on hydrolytic enzymes.

[0012] WO 2018 / 086847 A1 discloses amylases with specific amino acid sequences that are particularly suitable for aqueous detergent compositions. This document mentions that reducing agents and antioxidants increase the stability of enzymes. Sodium sulfite and reducing sugar compounds are given as examples.

[0013] The aim of the present invention was to provide an aqueous liquid composition for hand dishwashing that is mild and effective, has a stable storage life, can be dosed economically, provides excellent cleaning results even after storage, and facilitates hand dishwashing.

[0014] This objective was achieved by the aqueous hand dishwashing composition of the present invention by providing a balanced system of components that makes the composition stable in storage (no phase separation, no precipitation of components, maintenance of the activity of the ingredients), is environmentally friendly and can be dosed accurately and therefore economically due to its viscosity. SUMMARY OF THE INVENTION

[0015] The aspects of the invention are: 1. Aqueous liquid hand dishwashing composition comprising at least 35% by weight water and (i) a surfactant system comprising at least one anionic surfactant (ia) and at least one amine oxide surfactant (ib), (ii) at least one enzyme selected from protease and amylase, and (iii) an inorganic sulfur-based antioxidant. 2. Aqueous liquid hand dishwashing composition according to aspect 1, wherein the surfactant system (i) comprises at least one anionic surfactant (ia) selected from the group consisting of alkyl sulfate, alkyl alkoxy sulfate or alkyl poly(alkoxy sulfate) (also known as alkyl ether sulfate or fatty alcohol ether sulfate), alkyl sulfonate, alkyl sec sulfonate, alkylbenzene sulfonate or a mixture thereof. 3. Aqueous liquid hand dishwashing composition according to aspect 2, wherein the surfactant system (i) comprises at least alkyl poly(alkoxy)sulfate as anionic surfactants (ia), and wherein a second, other anionic surfactant may be present. 4. Aqueous liquid hand dishwashing composition according to aspect 3, wherein the surfactant system (i) comprises as anionic surfactants (ia) at least one alkyl poly(alkoxy) sulfate and one alkyl sulfonate, wherein the alkyl sulfonate is preferably an alkyl sec sulfonate. 5. Aqueous liquid hand dishwashing composition according to any of the above aspects, wherein the at least one amine oxide surfactant (ib) of the surfactant system (i) is selected from the group consisting of alkyl dimethylamine oxides, alkylamidoamine oxides and alkoxyalkylamine oxides. 6. Aqueous liquid hand dishwashing composition of aspects 2 to 4, wherein the alkyl chain in one of the surfactants (ia) or (ib) mentioned is a saturated or unsaturated C 6- 22 -Alkyl group, such as a C 8-13 -alkyl group, in particular a saturated C 10-16 -alkyl group, for example a saturated C 12-14 -Alkyl group, is. 7. Aqueous liquid hand dishwashing composition according to any of the above aspects, wherein the amine oxide is selected from C 10-14 -Alkyl-N,N-dimethylamine oxide, in particular lauryldimethylamine oxide, cocamidopropylamine oxide, N-cocoalkyl-N,N-dimethylamine oxide, N-tallowalkyl-N,N-dihydroxyethylamine oxide, myristyl / cetyl-N,N-dimethylamine oxide or mixtures thereof. 8. Aqueous liquid hand dishwashing composition according to aspect 5, wherein the amine oxide surfactant is selected from dodecyldimethylamine oxide (i.e., lauryldimethylamine oxide; INCI: laurylamine oxide) or cocamidopropylamine oxide (INCI: cocamidopropylamine oxide). 9. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the surfactant system (i) further comprises at least one amphoteric or zwitterionic surfactant (ic) that is different from the amine oxide (ib), preferably a betaine. 10. Aqueous liquid hand dishwashing composition according to aspect 9, wherein the betaine is selected from any alkyl betaine, alkylamidobetaine, amidazolinium betaine, sulfobetaine (INCI Sultaine) or phosphobetaine, preferably one defined by formulas (I), (II) or (III) below. 11. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, comprising one or more fatty alcohol ether sulfates and an alkyl sulfonate, in particular an alkyl sec sulfonate, wherein the ratio of sulfate to sulfonate is in the range of 5:1 to 1:1, preferably 4:1 to 2:1, more preferably 3.5:1 to 2.5:1. 12. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the surfactant system (i) comprises at least sodium laureth sulfate and sodium C14-17 alkyl sec sulfonate as anionic surfactants (ia) and / or at least lauramine oxide as a surfactant (ib) and / or at least cocamidopropyl betaine as a surfactant (ic). 13. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects comprising as enzyme (ii) at least one amylase, preferably an alpha amylase. 14. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects comprising at least one protease as enzyme (ii). 15. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects comprising as enzymes (ii) at least one amylase and one protease. 16. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects comprising as an antioxidant (iii) at least one sulfur-containing compound selected from sulfite, bisulfite, metabisulfite and thiosulfate salts. 17. Aqueous liquid hand dishwashing composition according to aspect 16, wherein the counterion is selected from sodium, potassium, ammonium, magnesium, lithium or calcium, preferably from potassium or sodium, most preferably from sodium. 18. Aqueous liquid hand dishwashing composition according to aspect 16 or 17, wherein the antioxidant is sodium sulfite. 19. Aqueous liquid hand dishwashing composition according to one of the foregoing aspects, further comprising as compound (iv) an inorganic salt other than (iii). 20. Aqueous liquid hand dishwashing composition according to aspect 19, wherein the compound (iv) is selected from any inorganic salt having a water solubility of at least 300 g / l or at least 1 mol / l in deionized water at 20 °C. 21. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein compound (iv) is selected from sodium chloride, potassium chloride, ammonium chloride, magnesium chloride, calcium chloride, sodium sulfate or a mixture thereof, wherein compound (iv) is preferably sodium chloride. 22. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, further comprising as compound (v) a monohydric alcohol, preferably selected from methanol, ethanol, propanol, n-butanol, isobutanol, pentanol or hexanol, most preferably including at least ethanol. 23. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the total amount of the compound(s) (i) is 10 to 50 wt.%, in particular in the range of 15 to 45 wt.%, more preferably of 20 to 40 wt.%, more preferably of 25 to 38 wt.%, based on the total weight of the hand dishwashing composition. 24. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the total amount of the compound(s) (ia) provided as active ingredients is in the range of 6 to 35 wt.%, in particular in the range of 8 to 30 wt.%, more preferably in the range of 10 to 25 wt.%, more preferably in the range of 12 to 20 wt.%, based on the total weight of the hand dishwashing composition. 25. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the amount of fatty alcohol sulfates as part of compound (ia) is 5 to 20 wt.%, preferably 8 to 16 wt.%, in particular 10 to 15 wt.%, based on the total weight of the hand dishwashing composition. 26. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the amount of alkyl sulfonate(s), in particular an alkyl-sec-sulfonate as part of compound (ia), if present, is 2 to 10 wt.%, preferably 3 to 8 wt.%, in particular 4 to 6 wt.%, based on the total weight of the hand dishwashing composition. 27. Aqueous liquid hand dishwashing composition according to any of the above aspects, wherein the total amount of the compound(s) (ib) provided as active ingredients is in the range of 0.2 to 8 wt.%, in particular 0.3 to 7 wt.%, such as 0.5 to 6 wt.% or 0.6 to 5 wt.% or even 0.8 to 4 wt.%, based on the total weight of the hand dishwashing composition. 28. Aqueous liquid composition for hand dishwashing according to any of the foregoing aspects, wherein the total amount of the compound(s) provided as active ingredients (ic), if any, is in the range of 5 to 20 wt.%, preferably 8 to 18 wt.%, and more preferably in a total amount of at least 10.5 wt.%, or at least 11 wt.%, or even at least 12 wt.%, based on the total weight of the hand dishwashing composition. 29. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the total amount of the compound(s) provided as active ingredients (ii) is 0.0001 to 3 wt.% active enzyme protein, such as 0.0005 to 2 wt.% or even 0.001 to 1.5 wt.%, based on the total weight of the hand dishwashing composition. 30. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the total amount of the compound(s) (iii) provided as active ingredients is at least 0.0025%, preferably at least 0.005%, more preferably at least 0.01% and most preferably at least 0.015%, such as 0.0025% to 2%, preferably 0.005% to 1%, more preferably 0.01% to 0.8% and particularly 0.015% to 0.5% or 0.015% to 0.1% by weight, based on the total weight of the hand dishwashing composition. 31. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, comprising the compound (iv), wherein preferably the total amount of the compound(s) (iv) provided as active ingredients is 1 to 12 wt.% or 2 to 10 wt.%, such as 2.5 to 8 wt.%, preferably 3.5 to 7.5 wt.%, more preferably 4.5 to 7.2 wt.% or 5 to 7 wt.% of the composition, based on the total weight of the hand dishwashing composition. 32. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, comprising compound (v), wherein the total amount of compound(s) (v) provided as active ingredients is 0.2 to 8 wt.% or 1 to 6 wt.%, preferably 1.5 to 5 wt.%, more preferably 2 to 4 wt.%, based on the total weight of the hand dishwashing composition. 33. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the total amount of water present in the composition is in the range of 35 to 80 wt.% or 35 to 75 wt.% or 40 to 75 wt.% or 40 to 70 wt.%, or 45 to 70 wt.%, or 45 to 65 wt.%, or even 50 to 65 wt.% water in which the other essential and optional components are dissolved, dispersed or suspended, wherein water is preferably present in an amount of 38 to 72 wt.% or in an amount of 42 to 70 wt.%, 45 to 68 wt.% or 50 to 65 wt.%, based on the total amount of the dishwashing composition. 34. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the viscosity of the composition is in the range of 200 to 8000 mPa*s, preferably in the range of 500 to 7000, or of 800 to 6000, preferably of 1000 to 5000 or of 1200 to 4000 mPa*s at 20 °C (Brookfield viscometer, 3 rpm, spindle 62). 35. Aqueous liquid hand dishwashing composition according to one of the above aspects, wherein the composition is free from at least one of the following compounds: - inorganic peroxides, - polymeric organic builder compounds, such as all types of polyacrylic acid derivatives, or - Complexing agents, such as aminopolycarboxylates, such as MGDA, EDTA, GLDA, IDS, etc., or - Preservatives such as Methylisothiazolinone (MIT), Benzisothiazolinone (BIT), Methylchloroisothiazolinone (CMIT) or - Sodium, potassium or ammonium cumenesulfonate or - Potassium acetate, sodium acetate or any other acetate salt or - Sodium carbonate or - Poly-carbohydrates or - Cellulase, catalase or lipase enzymes or - inorganic builder compounds such as phosphates, zeolites or - organic builder compounds such as sodium citrate or citric acid or - non-ionic surfactants such as alkyl alkoxylates, such as alkyl ethoxylates or alkyl ethoxylate propoxylates, such as Deceth-8 or Laureth-2, or C10 Guerbet alcohol with 2EO groups, branched C12 alcohol with 6 to 8 EO groups or branched C8 with EO and PO groups, or preferably free of at least two, at least three or at least four of them, most preferably it contains none of the above. 36. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the composition has a pH value in the range of 6.5 to 8.5, as in the range of 6.8 to 8.2, preferably in the range of 7.0 to 8.0, more preferably 7.2 to 7.8 at 25 °C. 37. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the weight ratio of the fatty alcohol sulfate(s) to the alkyl sulfonate(s) is 10:1 to 1:10, or 8:1 to 1:8, or 5:1 to 1:5, or 4:1 to 1:4, or 3:1 to 1:3, ranges of 5:1 to 1:1 are also preferred, preferably 4:1 to 2:1, more preferably 3.5:1 to 2.5:1. 38. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, comprising surfactant(s) (ia) and (ib) in a weight ratio of 10:1 to 3:1, preferably 9:1 to 4:1, more preferably 8:1 to 4.5:1, and even more preferably 7:1 to 5:1. 39. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, comprising surfactants (ia) and (ic) in a weight ratio of 10:1 to 1:3 or of 8:1 to 1:3 or of 6:1 to 1:3 or of 5:1 to 1:3 or of 4:1 to 1:3 or of 3:1 to 1:3, preferably in a ratio of 2.5:1 to 1:2, more preferably 2:1 to 1:1.5, more preferably in a ratio of 1.5:1 to 1:1. 40. Aqueous liquid composition for handwashing dishes according to any of the foregoing aspects, wherein the composition at least sodium laureth sulfate and sodium C14-17 alkyl sec-sulfonate as compound (ia) at least lauramine oxide as compound (ib) at least cocamidopropyl betaine as a compound (ic) at least one amylase as a compound (ii) at least sodium sulfite as a compound (iii) contains. 41. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the composition further comprises at least sodium chloride as compound (iv). 42. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the composition further comprises at least ethanol as compound (v). 43. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, comprising the salt compound (iv) and the alcohol (v) in a weight ratio of 10:1 to 1:10 or of 8:1 to 1:8. Or of 7:1 to 1:6, or of 6:1 to 1:4, or of 5:1 to 1:2, as in a range of 5:1 to 1:1, or in a range of 5:1 to 1:0.9. 44. Aqueous liquid hand dishwashing composition according to any of the foregoing aspects, wherein the surfactant system consists of surfactants (ia), (ib) and (ic) and the composition does not contain any further surfactant. DETAILED DESCRIPTION OF THE INVENTION The cleaning composition

[0016] The cleaning composition is an aqueous liquid hand dishwashing composition, typically containing 35 to 80 wt.%, for example 35 to 75 wt.%, or 40 to 75 wt.%, or 45 to 70 wt.%, or 45 to 65 wt.%, or even 50 to 65 wt.% water, in which the other essential and optional components are dissolved, dispersed, or suspended. According to the invention, water is preferably present in an amount of 38 to 72 wt.%, or in an amount of 42 to 70 wt.%, 45 to 68 wt.%, 50 to 65 wt.%, or 54 to 63 wt.%, based on the total amount of the dishwashing composition.

[0017] The pH of the composition is preferably in the range of 5.5 to 9, more preferably from 6.0 to 8.5, even more preferably from 6.8 to 8.2 or from 7.0 to 8.0, and most preferably from 7.2 to 7.8, such as approximately 7.5, measured at 25 °C (the aqueous composition in the supplied form). The pH of the composition can be adjusted using pH-modifying ingredients known in the art.

[0018] To enable precise dosing, the viscosity of the composition is preferably in the range of 200 to 8000 mPa*s, preferably in the range of 500 to 7000 or 800 to 6000, preferably 1000 to 5000 or 1200 to 4000 mPa*s at 20 °C (Brookfield viscometer, 3 rpm, spindle 62).

[0019] It is highly preferred that the composition is free of hydrogen peroxide (H2O2), barium peroxide (BaO2), sodium peroxide (Na2O2), potassium peroxide (K2O2) and calcium peroxide (CaO2) and is preferably free of any inorganic peroxides.

[0020] According to the present application, a composition is "free from" a compound if that compound has not been intentionally added to the composition. However, if the compound is present as an impurity in another component added to the composition, it is considered "free from" if the amount of the compound in the composition is less than 0.1 wt.%, less than 0.05 wt.%, less than 0.01 wt.%, less than 0.001 wt.%, or even less than 0.0001 wt.%. In a particularly preferred embodiment, the composition is completely free from said compound, such that the composition contains 0 wt.% of said compound.

[0021] In contrast to the previously mentioned definition, the composition is “free from” any inorganic peroxide if it contains less than 0.0001 wt%, less than 0.00001 wt% or even less than 0.000001 wt%, preferably 0 wt% of the peroxide. Surfactant system (i)

[0022] The total surfactant content in the hand dishwashing composition is in the range of 10 to 50 wt.%, in particular in the range of 15 to 45 wt.%, more preferably in the range of 20 to 40 wt.%, and even more preferably in the range of 25 to 38 wt.%, based on the total weight of the hand dishwashing composition. Anionic surfactant (ia)

[0023] The total content of anionic surfactants is in the range of 6 to 35 wt.%, particularly in the range of 8 to 30 wt.%, more preferably 10 to 25 wt.%, and even more preferably 12 to 20 wt.%, based on the total weight of the handwashing liquid composition. The surfactant system (i) may comprise one, two, three, or more different types of the anionic surfactants listed below; preferably, the system (i) comprises at least one or at least two different anionic surfactants. Preferably, the surfactants are added as sodium or potassium salts, most preferably as sodium salts.

[0024] The anionic surfactant can be any anionic cleaning surfactant; preferred anionic surfactants are selected from the group consisting of alkyl sulfate, alkoxyalkyl sulfate, alkyl sulfonates, alkyl sec sulfonates, alkylbenzenesulfonate, and mixtures thereof. Preferred anionic surfactants are selected from alkyl sulfate, alkyl alkoxy sulfate or alkyl poly(alkoxy) sulfate (also known as fatty alcohol ether sulfates), alkyl sec sulfonates, and mixtures thereof, wherein a preferred alkyl alkoxy sulfate is alkyl ethoxysulfate. The most preferred anionic surfactants for use herein are alkyl ethoxysulfate surfactants and alkyl sec sulfonates.

[0025] For all the above-mentioned anionic surfactants, it is preferred that the alkyl chain has 6 to 20 carbon atoms, preferably 8 to 18, more preferably 10 to 18, even more preferably 10 to 16, and most preferably 12 to 14, or 12, or 14, or 16, or 18 carbon atoms. An alkyl chain with 14 to 17 carbon atoms is also preferred. The alkyl chain can be an aliphatic straight-chain or a branched, non-cyclic or cyclic, saturated or unsaturated chain, with an aliphatic straight-chain chain being preferred.

[0026] The hand dishwashing composition preferably contains one or more fatty alcohol ether sulfates. Fatty alcohol ether sulfates enable a stable foam volume in the presence of stains, especially grease stains on the surfaces to be cleaned, or in water. Fatty alcohol ether sulfates are products of sulfation reactions on alkoxylated alcohols. Alkoxylated alcohols are the reaction products of alkylene oxides, such as ethylene oxide or propylene oxide, with alcohols, such as aliphatic straight-chain or branched, acyclic or cyclic, saturated or unsaturated alcohols with 6 to 20, such as 8 to 18, and in particular 10 to 16 or 12 to 14 carbon atoms. For example, n moles of ethylene oxide and one mole of alcohol yield a complex mixture of addition products with varying degrees of ethoxylation, depending on the reaction conditions (n ​​= 1 to 30, for example 1 to 20, in particular 1 to 10, such as 2, 3, 4, 5, 6, 7, 8, 9 or 10).Such anionic surfactants are preferably included in the hand dishwashing composition according to the invention.

[0027] The hand dishwashing composition preferably contains one or more fatty alcohol sulfates in an amount of 5 to 20 wt.%, preferably 8 to 16 wt.%, and particularly 10 to 15 wt.%, based on the total weight of the cleaning agent. The fatty alcohol sulfate preferably has an average of 0.1 to 8, and even more preferably 0.2 to 5, alkoxy units, particularly ethoxy units. A particularly preferred fatty alcohol sulfate is sodium laureth sulfate with 1 to 8 EO units or 1 to 5 EO units. The raw material may also contain a small amount of non-ethoxylated fatty alcohol sulfate.

[0028] A second type of anionic surfactant may be present in the hand dishwashing composition. If a second type is present, it is preferably an alkyl sulfonate, in particular an alkyl sec-sulfonate. An alkyl sec-sulfonate with an alkyl chain as mentioned above (C6 to C) is particularly preferred. 20 ), wherein an alkyl chain of C 12 up to C 18 , especially from C 14 up to C 17 , is preferred.

[0029] The hand dishwashing composition preferably further contains at least one alkyl sulfonate, in particular an alkyl sec sulfonate, in an amount of 2 to 10 wt.%, preferably 3 to 8 wt.%, and in particular 4 to 6 wt.%, based on the total weight of the cleaning agent. A particularly preferred alkyl sec sulfonate is C 14-17 -Alkyl-sec-sulfonate.

[0030] It is preferred that the hand dishwashing composition contains one or more fatty alcohol sulfates and an alkyl sulfonate, in particular an alkyl sec sulfonate, wherein the ratio of the sulfate (of sulfates) to the sulfonate (to the sulfonates) may be in a range of 10:1 to 1:10 or 8:1 to 1:8, or 5:1 to 1:5, or 4:1 to 1:4, or 3:1 to 1:3, with ranges of 5:1 to 1:1, preferably 4:1 to 2:1, and even more preferably 3.5:1 to 2.5:1 being preferred.

[0031] Other sulfonate surfactants that may be present include water-soluble salts of C8–C8. 18 alkyl or hydroxyalkyl sulfonates; C 11 -C 18 Alkylbenzenesulfonate (LAS), modified alkylbenzenesulfonate (MLAS), as discussed in WO 99 / 05243, WO 99 / 05242, WO 99 / 05244, WO 99 / 05082, WO 99 / 05084, WO 99 / 05241, WO 99 / 07656, WO 00 / 23549 and WO 00 / 23548; methyl ester sulfonate (MES); and alpha olefin sulfonate (AOS). Amine oxide (ib)

[0032] The hand dishwashing composition comprises at least one amine oxide surfactant. The total amount of the at least one amine oxide in the composition is 0.2 to 8% by weight, in particular 0.3 to 7% by weight, for example 0.5 to 6% by weight, or 0.6 to 5% by weight, or even 0.8 to 4% by weight of the at least one amine oxide, based on the total weight of the hand dishwashing composition. These ranges of amounts refer to each individual type of amine oxide surfactant, but if more than one type is added, the specified range also refers to the total amount of amine oxide surfactants present in the composition.

[0033] Suitable amine oxides include alkylamine oxides such as alkyl-dimethylamine oxide, alkylamidoamine oxide and alkoxyalkylamine oxide, in particular, but not limited to, amine oxides that meet formula I, II or III. R 1 R 2 R 3 N + -O - (I) or R 1 -[CO-NH-(CH2) w]2 -N + (R 2 )(R 3 )-O - (II) or R 1 -N + -(CH2 CH2 OH)2 -O - (III) where R 1 a saturated or unsaturated C 6-22 Alkyl group is, for example, a C 8-18 Alkyl group, in particular a saturated C 10-16 Alkyl group, for example a saturated C 12- 14 Alkyl group, which is mediated via a carbonylamidoalkylene group -CO-NH-(CH2)2- in the alkylamidoamine oxides and via an oxaalkylene group -O-(CH2)z- in the alkoxyalkylamine oxides, where z is a number from 1 to 10, for example 2 to 5, in particular 3, where w is a number from 0 to 5, for example 0 to 2, in particular 0 or 1, and R 2 and R 3 independently of each other, a possibly hydroxy-substituted C 1-4 Alkyl group, such as a hydroxyethyl group, especially a methyl group.

[0034] Examples of suitable amine oxides are the following compounds: a C 10-14 -Alkyl-N,N-dimethylamine oxide, in particular lauryldimethylamine oxide, cocamidopropylamine oxide, N-cocoalkyl-N,N-dimethylamine oxide, cocamidopropyldimethylamine oxide, coco-bis(2-hydroxyethyl)amine oxide, N-tallowalkyl-N,N-dihydroxyethylamine oxide, myristyl / cetyl-N,N-dimethylamine oxide or mixtures thereof. Preferably, the amine oxide surfactant is selected from dodecyldimethylamine oxide (lauryldimethylamine oxide; INCI: laurylamine oxide) or cocamidopropylamine oxide (INCI: cocamidopropylamine oxide).

[0035] Other amine oxide surfactants may be present in the hand dishwashing detergent composition. Another amphoteric or zwitterionic surfactant (ic)

[0036] In addition to the above-mentioned amine oxide surfactant(s), the composition preferably comprises at least one further amphoteric or zwitterionic surfactant that is different from an amine oxide, most preferably a betaine or a sulfataine (i.e. a sulfobetaine) surfactant.

[0037] Suitable betaine surfactants include, for example, alkyl betaine, alkylamido betaine, alkylamidopropyl betaine, alkylamidopropyl dimethyl betaine, alkylamidopropyl dimethyl sulfobetaine, alkylamidopropyl hydroxysultaine, alkyl bis(2-hydroxyethyl) betaine, alkyl dimethyl betaine, amidazolinum betaine, sulfobetaine (INCI Sultaines), sulfonamido betaine and phosphobetaine, and preferably corresponds to formula (IV): R 4 -[CO-X(CH2) n ] x -N + (R 5 )(R 6 )-(CHz) m -[CH(OH)-CH2] y -Y - (IV) where R 4 a saturated or unsaturated C 6-22Alkyl group, preferably a C 8-18 Alkyl group, in particular a saturated C 10-16 Alkyl group, for example a saturated C 12-14 Alkyl group, is; X equals NH, NR 7 , where R 7 a C 1-4 Alkyl group, O or S n is a number from 1 to 10, preferably 2 to 5, in particular 3, x equals 0 or 1, preferably 1, R 5 , R 6 independently of each other a C 1-4 Alkyl groups, which may optionally be hydroxy-substituted, for example with hydroxyethyl, preferably with methyl. m is a number from 1 to 4, in particular 1, 2 or 3, y is equal to 0 or 1, and Y equals COO, SO3 , OPO(OR 8 )O or P(O)(OR 8 )O is, where R 8 a hydrogen atom or a C 1-4 It is an alkyl group.

[0038] Preferred betaines are alkyl betaines of formula (IVa), the alkylamidopropyl betaine of formula (IVb), the sulfobetaines of formula (IVc) and the amidosulfobetaine of formula (IVd); R 4 -N + (CH3)2 -CH2 COO - (IVa) R 4 -CO-NH(CH2)3 -N + (CH3)2 -CH2 COO - (IVb) R 4 -N + (CH3)2 -CH2 CH(OH)CH2 SO3 - (IVc) R 4 -CO-NH-(CH2)3 -N + (CH3)2 -CH2 CH(OH)CH2 SO3 - (IVd) where R 4 has the same meaning as in Formula IV. Particularly favored betaine compounds are the carbobetaine compounds [where Y - =COO - is], in particular a carbobetaine compound of formulas (IVa) and (IVb), even more preferred is the alkylamidopropylbetaine compound of formula (IVb).

[0039] Examples of suitable betaines and sulfobetaines are the following (named according to INCI): Almondamidopropyl betaine, Apricotamidopropyl betaine, Avocadamidopropyl betaine, Babassuamidopropyl betaine, Behenamidopropyl betaine, Behenyl betaine, Betaine, Canolamidopropyl betaine, Capryl / Capramidopropyl betaine, Carnitine, Cetyl betaine, Cocamidoethyl betaine, Cocamidopropyl betaine, Cocamidopropyl hydroxysultaine, Cocobetaine, Cocohydroxysultaine, Coco- / Oleamidopropyl betaine, Cocosultaine, 3-[(3-Cocamidopropyl)dimethylamino] 2-hydroxypropanesulfonate, Decyl betaine, Dihydroxyethyl oleylglycinate, Dihydroxyethyl soyglycinate, Dihydroxyethyl stearylglycinate, Dihydroxyethyl tallowglycinate, Dimethicone propyl PG betaine, Erucamidopropyl hydroxysultaine hydrogenated tallow betaine, isostearamidopropyl betaine, lauryl dimethyl betaine, lauramidopropyl betaine, lauryl betaine, lauryl hydroxysultaine, lauryl sultaine, milkamidopropyl betaine, minkamidopropyl betaine, myristamidopropyl betaine, myristyl betaine, oleamidopropyl betaine,Oleamidopropylhydroxysultaine, oleyl betaine, oleyl bis(hydroxyethyl) betaine, olivamidopropyl betaine, palmamidopropyl betaine, palmitamidopropyl betaine, palmitoylcarnitine, palm kernel elamidopropyl betaine, polytetrafluoroethylene acetoxypropyl betaine, ricinoleamidopropyl betaine, sesamidopropyl betaine, soyamidopropyl betaine, stearamidopropyl betaine, stearyl betaine, tallowamidopropyl betaine, tallowamidopropyl hydroxysultaine, tallow betaine, tallowdihydroxyethyl betaine, undecylenamidopropyl betaine and wheat germamidopropyl betaine.

[0040] One particularly preferred betaine is cocamidopropyl betaine.

[0041] The composition most preferably comprises a betaine surfactant. The surfactant (ic), in particular the betaine surfactant, is preferably present in the hand dishwashing composition in an amount of 5 to 20 wt.%, more preferably 8 to 18 wt.% of the total composition. In a preferred embodiment, the betaine is present in a total amount of at least 8 wt.%, at least 9 wt.% or at least 10 wt.%, particularly preferably at least 10.5 wt.% or at least 11 wt.% or even at least 12 wt.% of the total weight of the hand dishwashing composition.

[0042] The weight ratio of the total amount of anionic surfactants (ia) to the total amount of betaines (ic) can be in the range of 10:1 to 1:3, or 8:1 to 1:3, or 6:1 to 1:3, or 5:1 to 1:3, or 4:1 to 1:3, or 3:1 to 1:3, and is preferably in the range of 2.5:1 to 1:2, more preferably from 2:1 to 1:1.5, and particularly from 1.5:1 to 1:1. The cleaning composition can, for example, comprise a fatty alcohol ether sulfate such as laureth sulfate, an alkyl sec sulfonate such as C14-17 alkyl sec sulfonate, and a betaine such as cocamidopropyl betaine. The ratio (of the total amount) of the anionic surfactant(s) to the betaine(s) can then be as described, e.g. B. 2:1 to 1:1.5. It should be noted that the composition includes the betaine(s) in addition to the amine oxide (ib).

[0043] The surfactant system (i) may include further surfactants, which, however, are not necessary according to the invention. Non-ionic surfactant

[0044] The surfactant system (i) may, for example, comprise a suitable nonionic surfactant. Any nonionic surfactant, if present, is included in a typical amount of 0.1% to 30%, preferably 0.2% to 15%, most preferably 0.5% to 10% by weight of the composition. Suitable nonionic surfactants include fatty alcohols (aliphatic alcohols) or the condensation products of aliphatic alcohols with 1 to 25 moles of ethylene oxide. The alkyl chain of the aliphatic alcohol may be either straight-chain or branched, primary or secondary, and generally contains 8 to 22 carbon atoms. Particularly preferred are the condensation products of alcohols with an alkyl group comprising 10 to 18 carbon atoms, preferably 10 to 15 carbon atoms, with 2 to 18 moles, preferably 2 to 15, more preferably 5 to 12 of ethylene oxide per mole of alcohol.Particularly preferred non-ionic surfactants are the condensation products of Guerbet alcohols with 2 to 18 mol, preferably 2 to 15, more preferably 5 to 12 ethylene oxide per mol alcohol.

[0045] Other suitable non-ionic surfactants for use herein include fatty alcohol polyglycol ethers, alkyl polyglucosides and fatty acid glucamides.

[0046] In one embodiment, it is preferred that the composition does not contain any nonionic surfactants. Preferably, the surfactant system consists of surfactants (ia), (ib) and (ic). Enzymes (ii)

[0047] The hand-held dishwashing composition of the invention comprises at least one protease and / or one amylase enzyme. These enzymes are present in the composition in a total amount of approximately 0.0001 to 3 wt.% of active enzyme protein, such as 0.0005 to 2 wt.% or even 0.001 to 1.5 wt.%, based on the total weight of the composition. Further enzymes may be present, so that the total amount of enzymes in the dishwashing composition can be up to approximately 5 wt.%. Protease

[0048] The composition of the invention comprises at least one protease. Each protease may be present in the composition of the invention in a preferred amount of about 0.001 to about 2 wt%, preferably about 0.005 to about 1 wt%, or about 0.005 to about 0.5 wt%, or about 0.005 to about 0.1 wt%, and particularly about about 0.005 to about 0.08 wt% of active protease, based on the weight of the composition, wherein this amount of protease may be represented by one type of such enzyme or by more than one type. If more than one protease is present, the defined amount also refers to the total amount of proteases present in the composition.

[0049] Suitable proteases include those of bacterial, fungal, plant, viral, or animal origin, e.g., plant or microbial origin. Microbial origin is preferred. Chemically modified or genetically engineered mutants are included. The protease can be an alkaline protease, such as a serine protease or a metalloprotease. A serine protease, for example, can be from the S1 family, such as trypsin, or from the S8 family, such as subtilisin. A metalloprotease can be, for example, a thermolysin from the M4 family, or another metalloprotease, such as from the M5, M7, or M8 families.

[0050] The term "subtilase" or "subtilisin" refers to a subgroup of serine proteases according to Siezen et al., 1991, Protein Engng. 4: 719-737 and Siezen et al., 1997, Protein Science 6: 501-523. Serine proteases are a subgroup of proteases characterized by having a serine in their active site that forms a covalent adduct with the substrate. subtilases can be divided into six subgroups: the subtilisin family, thermitase family, the proteinase K family, the lantibiotic peptidase family, the kexin family, and the pyrolysin family.

[0051] Examples of subtilases are those derived from Bacillus, such as Bacillus lentus, B. alkalophilus, B. subtilis, B. amyloliquefaciens, Bacillus pumilus and Bacillus gibsonii, described in: US 7,262,042 and WO 2009 / 021867, as well as subtilisin lentus, subtilisin novo, subtilisin Carlsberg, Bacillus licheniformis, subtilisin BPN', subtilisin 309, subtilisin 147 and subtilisin 168, which are described in WO 89 / 06279, and protease PD138, which is described in (WO 93 / 18140). Other useful proteases may be those described in WO 92 / 175177, WO 01 / 16285, WO 02 / 026024 and WO 02 / 016547. Examples of trypsin-like proteases are trypsin (e.g. from pig or bovine tissue) and the Fusarium protease described in WO 89 / 06270, WO 94 / 25583 and WO 2005 / 040372, and the chymotrypsin proteases derived from Cellumonas described in WO 2005 / 052161 and WO 2005 / 052146.

[0052] Another preferred protease is the alkaline protease from Bacillus lentus DSM 5483, as described, for example, in WO 95 / 23221, and variants thereof as described in WO 92 / 21760, WO 95 / 23221, EP 1921 147 and EP 1921 148.

[0053] Examples of metalloproteases are the neutral metalloproteases described in WO 2007 / 044993 (Genencor Int.), such as those obtained from Bacillus amyloliquefaciens.

[0054] Examples of useful proteases are those in WO92 / 19729, WO96 / 034946, WO98 / 201 15, WO98 / 201 16, WO99 / 01 1768, WO01 / 44452, WO03 / 006602, WO2004 / 03186, WO2004 / 041979, WO2007 / 006305, WO2011 / 036263, WO2011 / 036264, in particular the variants with substitutions at one or more of the following positions: 3, 4, 9, 15, 27, 36, 57, 68, 76, 87, 95, 96, 97, 98, 99, 100, 101, 102, 103, 104, 106, 118, 120, 123, 128, 129, 130, 160, 167, 170, 194, 195, 199, 205, 206, 217, 218, 222, 224, 232, 235, 236, 245, 248, 252 and 274 using the BPN numbering. The subtilisin variants may preferably include one of the following mutations: S3T, V4I, S9R, A15T, K27R, *36D, V68A, N76D, N87S,R, *97E, A98S, S99G,D,A, S99AD, S101G,M,R, S103A, V104I,Y,N, S106A, G118V,R, H120D,N, N123S, S128L, P129Q, S130A, G160D, Y167A, R170S, A194P, G195E, V199M, V205I, L217D, N218D, M222S, A232V, K235L, Q236H, Q245R N252K, T274A (using the BPN numbering) or a combination of the above.

[0055] Suitable commercially available protease enzymes include those sold under the trade names Alcalase™, Duralase™, Durazym™, Relase™, Relase™ Ultra, Savinase™, Savinase™ Ultra, Primase™, Polarzyme™, Kannase™, Liquanase™, Liquanase™ Ultra, Ovozyme™, Coronase™, Coronase™ Ultra, Neutrase™, Everlase™, Progress Uno™, Blaze™, Blaze Pro™ and Esperase™ (Novonesis), as well as those sold under the trade names Maxatase™, Maxacal™, Maxapem™, Purafect™, Purafect Prime™, Preferenz™, Purafect MA™, Purafect Ox™, Purafect OxP™, Puramax™, Properase™, Effectenz™, FN2™, FN3™, FN4™, Excellase™, Opticlean™ and Optimase™ (Genencor / IFF), Axapem™ (Gist-Brocases NV), BLAP (sequence in Fig. represented by US5352604) and variants thereof (Henkel AG), Bioproteasa™ (Biokatal), Lavergy™ (BASF) and KAP (Bacillus alkalophilus subtilisin) sold by Kao. Amylase

[0056] The hand-washing composition of the present invention contains at least one amylase enzyme. The at least one amylase may be present in amounts of 0.0001 to 1 wt%, 0.0005 to 0.5 wt%, 0.001 to 0.1 wt%, 0.002 to 0.05 wt%, 0.002 to 0.04 wt%, or 0.003 to 0.025 wt% active enzyme protein, based on the weight of the composition, wherein this amount of amylase may be represented by one type of such enzyme or by more than one type. If more than one amylase is present, the defined amount also refers to the total amount of amylases present in the composition.

[0057] Suitable amylases include alpha-amylases and / or glucoamylases and can be of bacterial or fungal origin. Alpha-amylases are preferred. Chemically modified or genetically engineered mutants are included. Amylases include, for example, alpha-amylases derived from Bacillus, such as a specific strain of Bacillus licheniformis described in GB 1,296,839.

[0058] Suitable amylases include amylases with SEQ ID NO: 2 in WO 95 / 10603 or variants with 90% sequence identity to those with SEQ ID NO: 3. Preferred variants are described in WO 94 / 02597, WO 94 / 18314, WO 97 / 43424 and as SEQ ID NO: 4 in WO 99 / 019467, such as variants with substitutions at one or more of the following positions: 15, 23, 105, 106, 124, 128, 133, 154, 156, 178, 179, 181, 188, 190, 197, 201, 202, 207, 208, 209, 211, 243, 264, 304. 305, 391, 408 and 444.

[0059] Other suitable amylases include amylases with SEQ ID NO: 6 in WO 02 / 010355 or variants thereof with 90% sequence identity to their SEQ ID NO: 6. Preferred variants of SEQ ID NO: 6 are those with a deletion at positions 181 and 182 and a substitution at position 193. Other suitable amylases are hybrid alpha amylases comprising residues 1-33 of the alpha amylase from B. amyloliquefaciens, shown in SEQ ID NO: 6 of WO 2006 / 066594, and residues 36-483 of the alpha amylase from B. licheniformis, shown in SEQ ID NO: 4 of WO 2006 / 066594, or variants thereof with 90% sequence identity. Preferred variants of this hybrid alpha amylase are those with a substitution, deletion, or insertion at one or more of the following positions: G48, T49, G107, H156, A181, N190, M197, 1201, A209, and Q264. The most preferred variants of the hybrid alpha amylase, which replace residues 1-33 of alpha amylase from B.amyloliquefaciens, shown in SEQ ID NO: 6 of WO 2006 / 066594, and the residues 36-483 of SEQ ID NO: 4, are those with the substitutions: . □ M197T; □ H156Y+A181T+N190F+A209V+Q264S; or □ G48A+T491+G107A+H156 Y+A181T+N190F+1201 F+A209V+Q264S.

[0060] Other suitable amylases are those with SEQ ID NO: 6 in WO99 / 019467 or variants thereof with a sequence identity of 90% to SEQ ID NO: 6. Preferred variants of SEQ ID NO: 6 are those with a substitution, a deletion, or an insertion at one or more of the following positions: R181, G182, H183, G184, N195, 1206, E212, E216, and K269. Particularly preferred amylases are those with a deletion at positions R181 and G182 or at positions H183 and G184.

[0061] Other amylases that can be used are those with SEQ ID NO: 1, SEQ ID NO: 3, SEQ ID NO: 2, or SEQ ID NO: 7 from WO 96 / 023873, or variants thereof with a sequence identity of 90% to SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, or SEQ ID NO: 7. Preferred variants of SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, or SEQ ID NO: 7 are those with a substitution, deletion, or insertion at one or more of the following positions: 140, 181, 182, 183, 184, 195, 206, 212, 243, 260, 269, 304, and 476, where SEQ ID 2 from WO 96 / 023873 is to Numbering is used. Preferred variants are those with a deletion at two positions selected from 181, 182, 183 and 184, such as 181 and 182, 182 and 183 or positions 183 and 184.The most preferred amylase variants of SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 7 are those with a deletion at positions 183 and 184 and a substitution at one or more of positions 140, 195, 206, 243, 260, 304 and 476.

[0062] Other amylases that can be used are amylases with SEQ ID NO: 2 from WO08 / 153815, SEQ ID NO: 10 in WO 01 / 66712, or variants thereof with a sequence identity of 90% to SEQ ID NO: 2 in WO 08 / 153815 or a sequence identity of 90% to SEQ ID NO: 10 in WO 01 / 66712. Preferred variants of SEQ ID NO: 10 in WO 01 / 66712 are those with a substitution, a deletion, or an insertion at one or more of the following positions: 176, 177, 178, 179, 190, 201, 207, 211, and 264.

[0063] Other suitable amylases are those with SEQ ID NO: 2 from WO 09 / 061380 or variants with 90% sequence identity to SEQ ID NO: 2 thereof. Preferred variants of SEQ ID NO: 2 are those with a shortened C-terminus and / or a substitution, deletion, or insertion at one or more of the following positions: Q87, Q98, S125, N128, T131, T165, K178, R180, S181, T182, G183, M201, F202, N225, S243, N272, N282, Y305, R309, D319, Q320, Q359, K444, and G475. Preferred variants of SEQ ID NO: 2 are those that have a substitution at one or more of the following positions: Q87E,R, Q98R, S125A, N128C, T131 I, T165I, K178L, T182G, M201 L, F202Y, N225E,R, N272E,R, S243Q,A,E,D, Y305R, R309A, Q320R, Q359E, K444E and G475K and / or a deletion at position R180 and / or S181 or of T182 and / or G183. The most preferred amylase variants of SEQ ID NO: 2 are those with the following substitutions: □ N128C+K178L+T182G+Y305R+G475K; □ N128C+K178L+T182G+F202Y+Y305R+D319T+G475K; □ S125A+N128C+K178L+T 182G+Y305R+G475K; or □ S125A+N128C+T131I+T165I+K178L+T182G+Y305R+G475K □ where the C-terminal variants are shortened and optionally include a substitution at position 243 and / or a deletion at position 180 and / or position 181.

[0064] Other suitable amylases are those with SEQ ID NO: 1 from WO13184577 or variants with 90% sequence identity to SEQ ID NO: 1 thereof. Preferred variants of SEQ ID NO: 1 are those with a substitution, deletion, or insertion at one or more of the following positions: K176, R178, G179, T180, G181, E187, N192, M199, 1203, S241, R458, T459, D460, G476, and G477. Preferred variants of SEQ ID NO: 1 are those that have a substitution at one or more of the following positions: K176L, E187P, N192FYH, M199L, 1203YF, S241 QADN, R458N, T459S, D460T, G476K and G477K and / or a deletion at position R178 and / or S179 or of T180 and / or G181. The most preferred amylase variants of SEQ ID NO: 1 are those with the following substitutions: □ E187P+I203Y+G476K □ E187P+1203Y+R458N+T459S+D460T+G476K, wherein the variants optionally include a substitution at position 241 and / or a deletion at position 178 and / or position 179.

[0065] Other suitable amylases are those with SEQ ID NO: 1 from WO10104675 or variants with 90% sequence identity to SEQ ID NO: 1 thereof. Preferred variants of SEQ ID NO: 1 are those with a substitution, deletion, or insertion at one or more of the following positions: N21, D97, V128, K177, R179, S180, S1181, G182, M200, L204, E242, G477, and G478. Even more preferred variants of SEQ ID NO: 1 are those that have a substitution at one or more of the following positions: N21 D, D97N, V1281 K177L, M200L, L204YF, E242QA, G477K and G478K and / or a deletion at position R179 and / or S180 or of 1181 and / or G182. Most preferred amylase variants of SEQ ID NO: 1 are those with the following substitutions: N21D+D97N+V128I where the variants optionally also include a substitution at position 200 and / or a deletion at position 180 and / or position 181.

[0066] Other suitable amylases are the alpha amylase with SEQ ID NO: 12 in WO01 / 66712 or a variant with at least 90% sequence identity to SEQ ID NO: 12. Preferred amylase variants are those with a substitution, a deletion, or an insertion at one or more of the following positions of SEQ ID NO: 12 in WO01 / 66712: R28, R118, N174; R181, G182, D183, G184, G186, W189, N195, M202, Y298, N299, K302, S303, N306, R310, N314; R320, H324, E345, Y396, R400, W439, R444, N445, K446, Q449, R458, N471, N484. Particularly preferred amylases include variants with a deletion of D183 and G184 and with the substitutions R1 18K, N195F, R320K and R458K, as well as a variant that additionally has substitutions at one or more positions selected from the group: M9, G149, G182, G186, M202, T257, Y295, N299, M323, E345 and A339, with a variant that additionally has substitutions at all of these positions being most preferred.

[0067] Other examples are amylase variants as described in WO2011 / 098531, WO2013 / 001078 and WO2013 / 001087.

[0068] The preferred amylase in this invention is an alpha amylase.

[0069] Commercially available amylases include Duramyl™, Termamyl™, Fungamyl™, Stainzyme™, Stainzyme Plus™, Natalase™, Liquozyme X™, Achieve™, Achieve Alpha™, Amplify™, Amplify Prime™, and BAN™ (from Novonesis), as well as Rapidase™, Purastar™, Effectenz™, Powerase™, and Excellenz. Preferenz S1000™, Preferenz S100™, and Preferenz S110™ (from Genencor / IFF) are also available. Additional enzymes

[0070] The preferred enzyme combination includes a protease and an amylase, or a protease, an amylase, and a lipase. Optionally, the composition may also include a catalase.

[0071] If present, each additional enzyme (i.e., each enzyme present besides protease or amylase) may be present independently in an amount of active enzyme of 0.00001 to 1 wt%, 0.0001 to 0.5 wt%, or 0.001 to 0.1 wt% enzyme protein, based on the weight of the composition.

[0072] Additional enzymes that may be included in the composition of the invention include, but are not limited to, one or more enzymes such as lipase, catalase, carbohydratease, cellulase, cutinase, pectinase, mannanase, arabinase, galactanase, xylanase, perhydrolase, oxidase, e.g. laccase, and / or peroxidase.

[0073] Lipases and cutinase: Suitable lipases and cutinases include those of bacterial or fungal origin. Chemically modified or genetically engineered enzymes are included. Examples include lipase from Thermomyces, e.g., from T. lanuginosus (formerly called Humicola lanuginosa), as described in EP258068 and EP305216; cutinase from Humicola, e.g., BH insolens (WO96 / 13580); lipase from strains of Pseudomonas (some of which have since been renamed Burkholderia), e.g., BP alcaligenes or P. pseudoalcaligenes (EP218272), P. cepacia (EP331376), P. sp. Strain SD705 (WO95 / 06720 and WO96 / 27002), P. wisconsinensis (WO96 / 12012), Streptomyces lipases of the GDSL type (WO10 / 065455), cutinase from Magnaporthe grisea (WO10 / 107560), cutinase from Pseudomonas mendocina (US5,389,536), lipase from Thermobifida iusca (WO11 / 084412), Geobacillus stearothermophilus lipase (WO11 / 084417), lipase from Bacillus subtilis (WO11 / 084599) and lipase from Streptomyces griseus (WO11 / 150157) and S.pristinaespiralis (WO12 / 137147).

[0074] Other examples are lipase variants as described in EP407225, WO92 / 05249, WO94 / 01541, WO94 / 25578, WO95 / 14783, WO95 / 30744, WO95 / 35381, WO95 / 22615, WO96 / 00292, WO97 / 04079, WO97 / 07202, WO00 / 34450, WO00 / 60063, WO01 / 92502, WO07 / 87508 and WO09 / 109500.

[0075] Preferred commercial lipase products include Lipolase™, Lipex™, Lipolex™ and Lipoclean™ (Novozymes A / S), Lumafast™ (originally from Genencor) and Lipomax™ (originally from Gist-Brocades).

[0076] Lyases: The lyase can be a pectate lyase derived from Bacillus, especially B. licheniformis or B. agaradhaerens, or a variant derived from one of these species, e.g., as in US 6124127, WO 99 / 27083, WO 99 / 27084, WO 02 / 006442, WO 02 / 092741, WO 03 / 095638. Commercially available pectate lyases include XPect™, Pectawash™, and Pectaway™ (Novozymes A / S).

[0077] Mannanases: Suitable mannanases are those of bacterial or fungal origin. This also includes chemically or genetically modified mutants. The mannanase can be an alkaline mannanase of family 5 or 26. It can be a wild type from Bacillus or Humicola, in particular B. agaradhaerens, B. licheniformis, B. halodurans, B. clausii, or H. insolens. Suitable mannanases are described in WO 1999 / 064619. One commercially available mannanase is Mannaway™ (Novozymes A / S). Sulfur-based antioxidant (iii)

[0078] The hand-washing composition of the present invention comprises an antioxidant based on sulfur-containing reducing agents. Preferred antioxidants are inorganic sulfur-based antioxidants, such as sulfite, bisulfite, metabisulfite, and thiosulfate salts. Some examples of these antioxidants are listed below as sodium salts; however, they can also be used as potassium, ammonium, magnesium, lithium, or calcium salts. - Sodium sulfite (Na2SO3) - Sodium bisulfite or sodium hydrogen sulfite (NaHSO3) - Sodium metabisulfite or sodium pyrosulfite (Na2S3O3) - Sodium pyrosulfite (Na2S2O3)

[0079] Preferred inorganic sulfur-based antioxidants are: - Sodium sulfite (Na2SO3) - Sodium bisulfite (NaHSO3) - Sodium metabisulfite (Na2S2O5) - Sodium thiosulfate (Na2S2O3) - Potassium sulfite (K2SO3) - Potassium bisulfite (KHSO3) - Potassium metabisulfite (K2S2O5) - Potassium thiosulfate (K2S2O3) - Calcium sulfite (CaSO3) - Calcium bisulfite (Ca(HSO3)2) - Calcium thiosulfate (CaS2O3) - Ammonium bisulfite (NH4HSO3) - Ammonium thiosulfate ((NH4)2S2O3)

[0080] The composition according to the invention comprises the antioxidant in an amount suitable to decompose any inorganic peroxide present in any of the compounds added to the composition, such as the surfactant(s). On the other hand, the added amount should not adversely affect the detergent composition.

[0081] The antioxidant is preferably added in an amount of at least 0.0025 wt.% of the sulfur-based antioxidant, preferably at least 0.005 wt.%, more preferably at least 0.01 wt.%, and most preferably at least 0.015 wt.% of the composition. The composition preferably comprises 0.0025 to 2%, more preferably 0.005 to 1%, more preferably 0.01 to 0.8%, and in particular 0.015 to 0.5% or 0.015 to 0.1 wt.% of the sulfur-based antioxidant composition.

[0082] Preferably, the composition comprises the sodium or potassium salt of an inorganic, sulfur-based antioxidant; more preferably, it comprises the sodium salt. Preferably, the composition also comprises sodium sulfite. Inorganic peroxide

[0083] Some of the raw materials used as ingredients for the present dishwashing composition may contain small amounts of inorganic peroxides. However, these amounts of peroxides can have a negative effect on the other ingredients of the composition according to the invention. Therefore, it is highly preferred that these (small) amounts of inorganic peroxides degrade within the composition. Therefore, the composition of the invention preferably contains no inorganic peroxide. This means that it contains less than 100 ppm, preferably less than 10 ppm, even more preferably less than 1 ppm or less than 0.1 ppm of any inorganic peroxide. It is particularly preferred that the composition contains no traces of the aforementioned compounds, such that these compounds are present in an amount of 0.00 wt.%.

[0084] Inorganic peroxides include, in particular, hydrogen peroxide (H2O2), barium peroxide (BaO2), sodium peroxide (Na2O2), potassium peroxide (K2O2) and calcium peroxide (CaO2).

[0085] The amount of peroxide present in the dishwashing detergent composition is reduced by the presence of the sulfur-based inorganic antioxidant described above. Inorganic salt (iv)

[0086] The dishwashing composition preferably comprises an inorganic salt that is distinct from the sulfur-based inorganic antioxidant. If present, compound (iv) is selected from any inorganic salt having a water solubility of at least 300 g / l or at least 1 mol / l in deionized water at 20 °C; preferably, compound (iv) is selected from sodium chloride, potassium chloride, ammonium chloride, magnesium chloride, calcium chloride, sodium sulfate, or a mixture of the aforementioned compounds, with sodium chloride being the most preferred compound (iv).

[0087] The inorganic salt (iv) is preferably present in a weight amount of 1 to 12 wt.% or 2 to 10 wt.%, for example 2.5 to 8 wt.%, preferably 3.5 to 7.5 wt.%, more preferably 4.5 to 7.2 wt.% or 5 to 7 wt.%, and preferably serves to stabilize the dishwashing composition. Alternatively, the inorganic salt can be present in a concentration of 0.1 to 3 mol / l or 0.2 to 2.5 mol / l, for example 0.5 to 2.2 mol / l, preferably 0.8 to 2 mol / l, more preferably 1 to 1.6 mol / l. Monohydric alcohol (v)

[0088] The composition may contain a monohydric alcohol. If present, it may be in an amount of 0.2 to 8 wt%, preferably 1 to 6 wt%, more preferably 1.5 to 5 wt%, and even more preferably 2 to 4 wt%. The alcohol may be selected from methanol, ethanol, propanol, n-butanol, isobutanol, pentanol, or hexanol, preferably including at least ethanol.

[0089] In order to achieve a balanced stabilization and to maintain the activity and dissolution of all components of the dishwashing composition of the present invention, it is preferred to use the salt compound (iv) and the monohydric alcohol (v) in a weight ratio of 10:1 to 1:10 or of 8:1 to 1:8 or of 7:1 to 1:6, or of 6:1 to 1:4, or of 5:1 to 1:2, for example in a range of 5:1 to 1:1, or in a range of 5:1 to 1:0.9. Dyes

[0090] The detergent composition may contain one or a combination of two, three, or more dyes. Preferred dyes are listed below and, where possible, identified by their Colour Index name or number: Acid Yellow 3 (CI 47005), Acid Yellow 17 (CI 18965), Acid Yellow 23 (CI 19140), Acid Yellow 36 (CI 13065), Acid Yellow 73 (CI 45350), Acid Yellow 93 (CI 48160), Direct Yellow 28 (CI 19555), Direct Yellow 132, Food Colour Yellow 3 (CI 15985), Food Colour Yellow 13 (CI 47005), Pigment Yellow 1 (CI 11680), Pigment Yellow 3 (CI 11710), Pigment Yellow 13 (CI 21100), Pigment Yellow 42 (CI 77492), Acid Orange 7 (CI 15510), Acid Orange 10 (CI 16230), Pigment Orange 13 (CI 21110), Acid Blue 1 (CI 42045) Acid Blue 3 (CI 42051), Acid Blue 9 (CI 42090), Acid Blue 62, Acid Blue 80 (CI 61585), Acid Blue 93 (CI 42780), Acid Blue 182, Acid Blue 225, Basic Blue 41, Direct Blue 86 (CI 74180), Direct Blue 199 (CI 74190), Food Blue 5 (CI 42051), Food Blue 5:2 (CI 42051:2), Pigment Blue 15 (CI 74160), Pigment Blue 15:1 (CI 74160), Pigment Blue 15:3 (CI 74160), Pigment Blue 29 (CI 77007), Solvent Blue 104 (CI 61568), Acid Green 1 (CI 10020), Acid Green 16, Acid Green 25 (CI 61570), Acid Green 28,Acid Green 81, Food Coloring Green 3 (CI 42053), Pigment Green 7 (CI 74260), Reactive Green 12, Solvent Green 3 (CI 61565), Solvent Green 7 (CI 59040), Solvent Green 28 (CI 625580), Acid Violet 43 (CI 60730), Acid Violet 48, Acid Violet 54, Acid Violet 126, Direct Violet 66 (CI 29120), Pigment Violet 23 (CI 51319), Solvent Violet 13, Acid Red 1 (CI 18050), Acid Red 14 (CI 14720), Acid Red 18 (CI 16255), Acid Red 27 (CI 16185), Acid Red 33 (CI 17200), Acid Red 52 (CI 45100), Acid Red 131 Acid Red 249 (CI 18134), Food Red 1 (CI 73360), Food Red 14 (CI 45430), Food Red 17 (CI 16035), Pigment Red 5 (CI 12490), Pigment Red 112 (CI 12370), Pigment Red 146 (CI 12485), Pigment Red 181 (CI 73360), Reactive Red 180 (CI 181055), Solvent Red 195, Acid Black 2, Pigment Black 7 (CI 77266).

[0091] Polymer dyes, such as Milliken's Liquitint series, or natural dyes are also preferred. Natural dyes are dyes or colorants derived from plants, invertebrates, or minerals, such as dyes from plant sources (roots, berries, bark, leaves, wood, etc.) and other biological sources (fungi, etc.). Further connections

[0092] The detergent composition described herein may contain a number of optional ingredients commonly used in liquid hand dishwashing detergents, such as pH regulators, preservatives, buffers or other diluents or solvents compatible with the formulation, fragrances, odor control agents, rheology modifiers, deterrents, pH regulators, hydrotropes, pigments, dyes or opacifiers, but also any other desired compounds such as plasticizers, humectants, skin rejuvenating agents, magnesium cations, carboxylic acids, scouring particles, bleaching agents and bleach activators, pearls, pearlescent particles, microcapsules, antibacterial agents, unless expressly excluded above.

[0093] Another preferred component of the composition is optionally a pH-adjusting compound. The pH value of the finished composition is preferably in the range of pH 6.5 to 8.5, more preferably in the range of pH 6.8 to 8.2 or even in the range of pH 7.0 to 8.0. EXAMPLES

[0094] The following examples describe embodiments of the invention, which are not to be understood as limiting the invention to the embodiments mentioned.

[0095] A basic composition comprising the following components: (ia) Alkyl ether sulfate 11 % (ia) secondary alkanesulfonate 3,5 (ib) Amine oxide 2,5 (ic) Betaine 11 (ii) Protease / Amylase 0.001-1.5% (as active enzyme protein) (iii) Sodium sulfite 0,005-0,5 % (iv) sodium chloride 0-7% (v) Ethanol 0-7 pH regulator, perfume, dyes < 2 Water ad 100 This was used to investigate the stability of the composition, the stability of the active ingredients, and the balanced system for cleaning performance. Compounds (ii) to (v) were added in varying amounts, as indicated below. All percentages are given as weight percent.

[0096] The surfactants used in these examples and all other ingredients have been tested, selected and / or manufactured to ensure that they contribute less than 0.25 ppm, preferably no inorganic peroxide, to the composition. Example 1: Enzyme stability:

[0097] The amine oxide used in the example compositions was a 30 wt% solution of the active ingredient. For a quantity of 2.5 wt% active amine oxide, 8.3 wt% of the 30 wt% amine oxide solution was dosed.

[0098] In this experiment, two samples of the same amine oxide were used. One sample contained approximately 300 ppm residual hydrogen peroxide (used in compositions 1 and 2), and the other sample contained approximately 480 ppm residual hydrogen peroxide (used in composition 3). These concentrations of residual hydrogen peroxide correspond to amounts of 25 ppm and 40 ppm hydrogen peroxide, respectively, in the final compositions.

[0099] All other ingredients used in the examples were tested, selected and / or manufactured to ensure that they contribute less than 0.25 ppm, preferably no inorganic peroxide, to the composition.

[0100] The basic composition was supplemented with sodium sulfite to obtain the following compositions 1 to 3: Table 1 H2 O2 Sodium sulfite Salt (iv) Ethanol Composition 1 25 ppm - - - Composition 2 25 ppm 0.02 wt. - - Composition 3 40 ppm 0.02 wt. -

[0101] All compositions tested in this experiment contained subtilisin and alpha-amylase. The active subtilisin content in the composition was 0.027 wt%, and the active alpha-amylase content was 0.009 wt%. Each enzyme was added in its commercially available form at a dosage of 0.30 wt%.

[0102] The compositions were made up to 100% by weight with water.

[0103] These three compositions were prepared and stored at 30 °C for several weeks. The activity of subtilisin and alpha-amylase was determined on the day of preparation and after 1, 2, 4, and 8 weeks of storage at 30 °C. The respective activity was calculated based on the enzyme activity immediately after preparation of the compositions.

[0104] The following tables show the stability of the enzymes in these compositions. Table 2: Stability of Alpha-Amylase start After 1 week After 2 weeks After 4 weeks After 8 weeks Composition 1 100 33 30 27 23 Composition 2 100 90 83 77 70 Composition 3 100 87 73 63 60 Table 3: Stability of subtilisin Beginn After 1 week After 2 weeks After 4 weeks After 8 weeks Composition 1 100 83 73 70 63 Composition 2 100 100 97 93 93 Composition 3 100 97 93 93 90

[0105] The results show that an inorganic sulfur-based oxidizing agent significantly improves the stability of alpha-amylase and subtilisin in the surfactant-based composition containing traces of inorganic peroxide. Example 2: Storage stability

[0106] During storage of compositions 1 to 3, it was observed that compositions 2 and 3 showed slight precipitation after 4 weeks, which could be dissolved again by gentle swirling.

[0107] To stabilize the composition, sodium chloride and ethanol were added to composition 2 in the amounts specified in Table 4. Table 4 H2 O2 Sodium sulfite Salt (iv) Ethanol Basic composition - - - - Composition 2 25 ppm 0.02 wt.% - - Composition 4 25 ppm 0.02 wt.% 1 wt.% 2.5 wt.% Composition 5 25 ppm 0.02 wt.% 2.5 wt.% 2.5 wt.% Composition 6 25 ppm 0.02 wt.% 5 wt.% 2.5 wt.%

[0108] After 8 weeks of storage, the compositions were examined to determine whether any precipitation was visible. The results are shown in Table 5. Table 5 Look Activity Protease Amylase activity Basic composition Clear solution 92 69 Composition 2 Light precipitation 93 70 Composition 4 Slight cloudiness 92 67 Composition 5 Clear solution 93 68 Composition 6 Clear solution 94 68

[0109] The addition of salt and ethanol led to a stabilization of the composition, so that all ingredients remained dissolved without negatively affecting the activity of the enzymes. Example 3: Color stability

[0110] Compositions 7, 8, and 9 were prepared and were very similar to composition 6. Differences lie in the amounts of sodium sulfite used and in the presence of dye. The dye used in this experiment was a mixture of Acid Violet 43 and Food Blue 5 in a 6:1 ratio, with a total amount of 0.0020 wt% in the compositions. Table 5 H2O2 Sodium sulfite dye Composition 7 25 ppm No positive Composition 8 25 ppm 0.02 wt. positive Composition 9 25 ppm 0.04 wt. positive

[0111] The samples were all the same color at the time the cleaning agents were manufactured. The samples were stored on a windowsill for 12 weeks and then in the dark in a cupboard for another 12 weeks. The temperature during the test was kept stable between 20°C and 25°C.

[0112] After these 24 weeks, color stability was tested by measurement in the L*a*b* color space. These values ​​are listed in Table 6. Table 6 L* a* b* Composition 7 55,86 -20,36 -18,08 Composition 8 47,56 -19,33 -27,50 Composition 9 41,94 -14,50 -37,60

[0113] The values ​​for L*, the black-white axis, show that the presence of sodium sulfite slows down the discoloration towards a higher L* value. The values ​​for b*, the blue-yellow axis, show that the presence of sodium sulfite slows down the discoloration of the blue color.

[0114] The presence of sodium sulfite clearly stabilizes the dyes used in the tested aqueous hand dishwashing composition. Example 4: Model compositions

[0115] Below are some non-restrictive examples that represent examples of the claimed aqueous liquid composition for hand dishwashing. (4.1) (4.2) (4.3) (4.4) (4.5) (4.6) (4.7) (4.8) ia) anionic surfactant 12-20 6-35 12 8 12,4 18,2 12,4 12,4 ib) Amine oxide surfactant 0,8 - 4 0,2 - 8 0,8 - 4 0,6 2,5 3,5 2,5 2,5 ic) amphoteric surfactant 8 - 18 0-20 >8 5,3 9,5 14,6 0 9,5 other surfactants 0 - 10 0 - 10 0-7 0,8 3,5 0 3,5 3,5 ii) Enzyme(s) 0,001 - 1,5 0,001 - 2 0,005 - 0,1 0,01 0,02 0,035 0,02 0,02 iii) Sulfur-based antioxidant 0,02 - 0,5 0,005 - 5 0,025-0,1 0,015 0,03 0,08 0,03 2 iv) inorganic salt 2 - 12 1 - 12 4,5 - 7 2 5,5 9,8 9,8 5,5 v) monohydric alcohol 2 - 4 1 - 6 0 - 4 1,5 3 4,3 4,3 3 Optional additional ingredients 0 - 8 <6 <3 0,5 0,9 1,6 0,9 0,9 Water ad 100 30-80 40 - 70 81,3 62,6 47,9 66,6 60,7 (4,9) (4,10) (4,11) (4,12) (4,13) (4.14) (4.15) (4.16) ia)Sodium lauryl ether sulfate (1-5 EO) 10-15 5-25 8-18 9 13 19 10 19 ia) Na C14-17Alkyl-sec-sulfonate 4-6 1,5-12 1,5-8 3,3 4,4 5,1 3,5 5,1 ib)Lauryldimethylamine oxide 0,8 - 4 0,2-8 0,8 - 4 0,6 2,5 3,5 2,5 3,5 ic)Cocamidopropylbetain 8-18 0-20 >8 5,3 9,5 14,6 11 9,5 ii) Protease 0,001- 0,05 0,001- 0,04 0,008- 0,03 0,005 0,012 0,02 0,012 0,012 ii) Alpha amylase 0,001- 0,05 0,001- 0,04 0,005- 0,03 0,003 0,007 0,01 0,007 0,007 iii) Sodium sulfite 0,02 - 0,5 0,005-5 0,025-0,1 0,015 0,03 0,08 0,03 0,02 iv) Sodium chloride 2-12 1 - 12 4,5 - 7 2 5,5 9,8 5 6 v) Ethanol 2-4 1-6 2-4 1,5 3 4,3 3 2,2 Optional additives 0-8 <6 <3 0,5 0,9 1,6 0,7 1 Water ad100 30 - 80 40 - 70 81,3 62,6 47,9 64,3 53,7 (4,17) (4,18) (4,19) (4,20) (4.21) ia) Sodium lauryl ether sulfate (1-5 EO) 13 13 13 13 13 ia) Na C14-17 alkyl sec-sulfonate 4,4 4,4 4,4 4,4 4,4 ib) Lauryldimethylamine oxide 2,5 2,5 2,5 2,5 2,5 ic) Cocamidopropyl betaine 9,5 9,5 9,5 9,5 9,5 ii) Protease 0,012 0,012 0,012 0,012 0,012 ii) Alpha amylase 0,007 0,007 0,007 0,007 0,007 iii) Sodium bisulfite 0,03 iii) Sodium metabisulfite 0,03 iii) Sodium thiosulfate 0,03 iii) Potassium sulfite 0,03 iii) Potassium bisulfite 0,03 iv) Sodium chloride 5,5 5,5 5,5 5,5 5,5 v) Ethanol 3 3 3 3 3 Optional additional ingredients 0,9 0,9 0,9 0,9 0,9 Water 61,2 61,2 61,2 61,2 61,2 (4,22) (4,23) (4,24) (4,25) (4,26) (4.27) (4.28) ia) Sodium lauryl ether sulfate (1-5 EO) 17 13 13 13 13 13 17 ia) Na C14-17 alkyl sec-sulfonate 4,4 4,4 4,4 4,4 4,4 ib) Lauryldimethylamine oxide 2,5 2,5 2,5 2,5 2,5 2,5 ib) Cocamidopropylamine oxide 2,5 ic) Cocamidopropyl betaine 9,5 9,5 9,5 9,5 9,5 ic) caprylic / capramidopropyl betaine 9,5 ic) Cocobetain 9,5 ii) Protease 0,012 0,012 0,012 0,012 0,012 0,012 0,012 ii) Alpha amylase 0,007 0,007 0,007 0,007 0,007 0,007 0,007 iii) Sodium sulfite 0,03 0,03 0,03 0,03 0,03 0,03 0,03 iv) Sodium chloride 5,5 5,5 5,5 5,5 5,5 5,5 5,5 v) Ethanol 3 3 3 3 3 3 Dyes 0,00005 - 0,005 Food coloring blue 5 0,00005 - 0,005 Optional additives 0,9 0,9 0,9 0,9 0,9 0,9 0,9 Water 61,6 61,6 61,6 61,6 61,6 61,6 64,6

[0116] The pH of these compositions has been adjusted between 6.5 and 8.2. All amounts are given as weight percent. The amount of enzymes, protease, and alpha-amylase is given as the active enzyme protein. Excipients may include solvents, hydrotropes, pH regulators, fragrances, dyes, opacifiers, antibacterial agents, rheology modifiers, processing aids, complexing agents, and aversives. QUOTES INCLUDED IN THE DESCRIPTION

[0000] This list of documents cited by the applicant was automatically generated and is included solely for the reader's convenience. The list is not part of the German patent or utility model application. The DPMA accepts no liability for any errors or omissions. Cited patent literature

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[0050]

Claims

Aqueous liquid hand dishwashing composition comprising at least 35% by weight water and (i) a surfactant system comprising at least one anionic surfactant (ia) and at least one amine oxide surfactant (ib), (ii) at least one enzyme selected from protease and amylase, (iii) an inorganic sulfur-based antioxidant. Aqueous liquid hand dishwashing composition according to claim 1, wherein the surfactant system (i) comprises at least one anionic surfactant (ia) selected from the group consisting of alkyl sulfate, alkyl alkoxy sulfate or alkyl poly(alkoxy) sulfate, alkyl sulfonate, alkyl sec sulfonate, alkyl benzene sulfonate or a mixture thereof, preferably at least one alkyl poly(alkoxy) sulfate. Aqueous liquid hand dishwashing composition according to one of the preceding claims, wherein the at least one amine oxide surfactant (ib) of the surfactant system (i) is selected from the group consisting of alkyl dimethylamine oxides, alkylamidoamine oxides and alkoxyalkylamine oxides. Aqueous liquid hand dishwashing composition according to any of the preceding claims, wherein the amine oxide (ib) is selected from C10-14-alkyl-N,N-dimethylamine oxide, in particular lauryldimethylamine oxide or cocamidopropylamine oxide, N-cocoalkyl-N,N-dimethylamine oxide, N-tallowalkyl-N,N-dihydroxyethylamine oxide, myristyl / cetyl-N,N-dimethylamine oxide or mixtures thereof, preferably selected from dodecyldimethylamine oxide (i.e. lauryldimethylamine oxide; INCI: laurylamine oxide) or cocamidopropylamine oxide (INCI: cocamidopropylamine oxide). Aqueous liquid hand dishwashing composition according to one of the preceding claims, wherein the surfactant system (i) further comprises at least one amphoteric or zwitterionic surfactant (ic) that is distinct from the amine oxide (ib), preferably a betaine. Aqueous liquid hand dishwashing composition according to claim 5, wherein the betaine is selected from any alkyl betaine, alkylamidobetaine, amidazolinium betaine, sulfobetaine (INCI Sultaines) or phosphobetaine and is preferably cocamidopropyl betaine. Aqueous liquid hand dishwashing composition according to any of the preceding claims, comprising as antioxidant (iii) at least one sulfur-containing compound selected from sulfite, bisulfite, metabisulfite and thiosulfate salts, preferably as potassium or sodium salts, most preferably as sodium salts. Aqueous liquid hand dishwashing composition according to one of the preceding claims, wherein an additional compound (iv) is present, selected from any inorganic salt having a water solubility of at least 300 g / l or at least 1 mol / l in deionized water at 20 °C, preferably the compound (iv) is selected from sodium chloride, potassium chloride, ammonium chloride, magnesium chloride, calcium chloride, sodium sulfate or a mixture of the aforementioned, wherein the compound (iv) preferably comprises at least sodium chloride. Aqueous liquid hand dishwashing composition according to one of the preceding claims, wherein the composition further comprises (v) a monohydric alcohol selected from methanol, ethanol, propanol, n-butanol, isobutanol, pentanol or hexanol, wherein preferably at least ethanol is present. Aqueous liquid hand dishwashing composition according to any one of the preceding claims, wherein the total amount of the compounds provided as active ingredients, independently of one another, for compound(i) is 10 to 50 wt.%, in particular in the range of 15 to 45 wt.%, more preferably in the range of 20 to 40 wt.%, and more preferably in the range of 25 to 38 wt.%, wherein the amount of (ia) is in the range of 6 to 35 wt.%, in particular in the range of 8 to 30 wt.%, more preferably in the range of 10 to 25 wt.%, and more preferably in the range of 12 to 20 wt.%, (ib), if present, in the range of 0.2 to 8 wt.%, in particular in the range of 0.3 to 7 wt.%, such as, for example, 0.5 to 6 wt.% or 0.6 to 5 wt.% or even 0.8 to 4 wt.%, based on the total weight of the hand dishwashing composition, (ic), if present, in the range of 5 to 20 wt.%. preferably 8 to 18 wt.%, even more preferably in a total amount of at least 10.5 wt.%, or at least 11 wt.%, or even at least 12 wt.%.-%, based on the total weight of the hand dishwashing composition,(ii) 0.0001 to 3 wt.% active enzyme protein, such as e.g. B. 0.0005 to 2 wt.% or even 0.001 to 1.5 wt.%, based on the total weight of the hand dishwashing composition,(iii) at least 0.0025%, preferably at least 0.005%, more preferably at least 0.01% and most preferably at least 0.015%, such as from 0.0025 to 2 wt.%, preferably from 0.005 to 1 wt.%, more preferably from 0.01 to 0.8 wt.% and particularly from 0.015 to 0.5 wt.% or from 0.015 to 0.1 wt.%,(iv) if present, in the range of 1 to 12 wt.%, such as 2 to 10 wt.% or 2.5 to 8 wt.%, preferably 3.5 to 7.5 wt.%, more preferably 4.5 to 7.2 wt.% or 5 to 7 wt.%,(v) if present, in the range of 0.2 to 6 wt.% or 1 to 6 wt.% or 1.5 to 5 wt.%, such as 2 to 4 wt.%, and water in an amount of 35 to 80 wt.% or in an amount of 35 to 75 wt.%.-%40 to 75% by weight, 45 to 70% by weight, 45 to 65% by weight, or 50 to 65% by weight, in each case based on the total amount of the corresponding ingredient(s) provided as active ingredient(s), and based on the total weight of the hand dishwashing composition. Aqueous liquid hand dishwashing composition according to any of the preceding claims, comprising surfactants (ia) and (ib) in a weight ratio of 10:1 to 3:1, preferably 9:1 to 4:1, more preferably 8:1 to 4.5:1, more preferably 7:1 to 5:1, and / or surfactants (ia) and (ic) in a weight ratio of 10:1 to 1:3 or 8:1 to 1:3 or 6:1 to 1:3 or 5:1 to 1:3 or 4:1 to 1:3 or 3:1 to 1:3, preferably 2.5:1 to 1:2, more preferably 2.5:1 to 1:1.5, more preferably 1.5:1 to 1:

1. Aqueous liquid hand dishwashing composition according to one of the preceding claims, comprising at least one alkyl poly(alkoxy) sulfate and optionally one alkyl sulfonate as compound (ia), preferably both types are present. Aqueous liquid hand dishwashing composition according to one of the preceding claims, wherein the composition contains at least sodium laureth sulfate and optionally sodium C14-17 alkyl sec sulfonate as compound (ia), at least lauramine oxide as compound (ib), at least cocamidopropyl betaine as compound (ic), at least an amylase as compound (ii), at least sodium sulfite as compound (iii), at least sodium chloride as compound (iv), and at least ethanol as compound (v). The aqueous liquid hand dishwashing composition according to one of the preceding claims, wherein the surfactant system (i) consists of the surfactants (ia), (ib) and (ic) and the composition does not contain any further surfactant.