HIFU-INDUCED CAVITATION WITH REDUCED POWER THRESHOLD

DE602010070034T2Active Publication Date: 2026-06-03BIOCARTIS NV

Patent Information

Authority / Receiving Office
DE · DE
Patent Type
Patents
Current Assignee / Owner
BIOCARTIS NV
Filing Date
2010-04-09
Publication Date
2026-06-03

AI Technical Summary

Technical Problem

Existing HIFU technologies require high power levels for both mixing and lysis, complicating the use of a single chamber and necessitating large transducers and liquid cooling, which can lead to excessive heating and material degradation.

Method used

The apparatus focuses high-intensity ultrasound waves on the liquid-air interface within a cartridge, creating a fountain that induces heterogeneous cavitation with a reduced power threshold, allowing for smaller transducers and solid-state coupling, thereby avoiding material degradation and enabling miniaturization.

Benefits of technology

This approach reduces the power required for cavitation, enabling smaller transducers, minimizing material degradation, and allowing for complete dry coupling, thus reducing costs and contamination risks while maintaining effective sample treatment.

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