SYSTEM AND METHOD FOR A PROTEIN-CORONA SENSOR ARRANGEMENT FOR EARLY DETECTION OF DISEASES
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Filing Date
- 2017-12-18
- Publication Date
- 2026-04-15
AI Technical Summary
Current methods for early cancer detection lack a broadly relevant platform that can identify cancer at various stages with sensitivity and specificity, particularly for types like lung cancer, where defined circulating biomarkers are elusive, leading to late detection and low survival rates.
A sensor array system that utilizes a combination of recognition of biomolecular fingerprints from a subject's sample, analyzing the protein corona patterns formed on liposomes in plasma, enabling early detection of cancer by identifying unique biomolecular fingerprints through multivariate analysis of protein corona signatures.
The system can accurately distinguish between healthy and cancerous states, including early cancer stages, without relying on specific biomarkers, allowing for early diagnosis and improved prognosis by detecting changes in biomolecule compositions associated with sensor elements.