METHOD FOR CONTINUOUS CHROMATOGRAPHIC SEPARATION AND DEVICE FOR CHROMATOGRAPHIC SEPARATION
Patent Information
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- MITSUBISHI CHEM AQUA SOLUTIONS CO LTD
- Filing Date
- 2019-02-28
- Publication Date
- 2026-06-10
AI Technical Summary
In continuous chromatographic separation methods, the consolidation of the separating agent often occurs due to increased pressure loss, leading to decreased separating performance and stability, especially when dealing with high-viscosity liquids like sugar solutions, which can also be affected by temperature changes in composition.
Implementing an upward stream in specific steps of the chromatographic separation process, combined with a downward stream in other steps, to maintain piston flow and prevent agent consolidation, while using a chromatographic separation device with switching portions to manage fluid direction effectively.
This approach reduces the likelihood of separating agent consolidation, maintains high separating performance, and reduces pressure loss, allowing for stable and efficient continuous chromatographic separation of components in liquids.