Device and method for post extubation dysphagia, antibacterial therapy, and detection and drainage of pharyngeal secretions

Abstract

A drainage device includes an elongate flexible conduit comprising a proximal end opening, a distal end opening and a lumen disposed therebetween. A multi-layer distal portion coaxially surrounding the lumen and having a porous outer surface layer, a porous interior layer and an intermediate absorbent layer therebetween. A drainage system and a device and method for treating dysphagia are also disclosed.

Description

A drainage device includes an elongated flexible catheter comprising a proximal opening, a distal opening, and a lumen disposed between the proximal and distal openings. Multiple distal portions coaxially surround the lumen and have a porous outer surface layer, a porous inner layer, and an intermediate absorbent layer therebetween. A drainage system and a device and method for treating dysphagia are also disclosed. Abstract

Claims

CLAIMSWhat is claimed is:1 . A drainage device comprising: an elongate flexible conduit comprising a proximal end opening, a distal end opening and a lumen disposed therebetween; and a multi-layer distal portion coaxially surrounding the lumen and having a porous outer surface layer, a porous interior layer and an intermediate absorbent layer therebetween.

2. The drainage device of claim 1 , wherein the porous interior layer comprises a multi-channel structure.

3. The drainage device of claim 2, wherein each channel of the multi-channel structure is in fluid communication with a drainage conduit extending proximally at least to the proximal end opening.

4. The drainage device of claim 2, wherein the multi-channel structure is a non- collapsible structure.

5. The drainage device of claim 1 , wherein the porous outer surface layer is a hydrophobic layer.

6. The drainage device of claim 1 , wherein the intermediate absorbent layer comprises a cellulose material.

7. drainage system comprising: the drainage device of claim 1 coaxially loaded over a feeding tube.

8. A drainage system comprising:the drainage device of claim 1 ; and a negative pressure source in fluid communication with channels of the porous interior layer.

9. A drainage system comprising: the drainage device of claim 1 ; and a sleeve configured to coaxially load over the drainage device and compress the multi-layer distal portion.

10. The drainage device of claim 1 , wherein the multi-layer distal portion comprises a plurality of struts.11 . The drainage device of claim 10, wherein the plurality of struts comprise a shapememory material.

12. The drainage device of claim 10, wherein the plurality of struts comprises three struts.

13. The drainage device of claim 10, wherein the plurality of struts are configured to initiate trifoliate compaction upon rotation.

14. The drainage device of claim 1 , wherein the multi-layer distal portion is configured to reduce in diameter upon actuation of a twisting motion.

15. The drainage device of claim 1 further comprising: a plurality of surface electrodes at least partially surrounding the lumen.

16. The drainage device of claim 15, wherein at least one of the plurality of surface electrodes is disposed on the porous outer surface layer.

17. The drainage device of claim 16 further comprising: ia controller configured to generate a suction signal upon detecting a threshold impedance from at least one of the plurality of surface electrodes.

18. The drainage device of claim 1 further comprising: a light source configured to apply visible blue light in 400 to 470 nm spectra within the lumen.

19. The drainage device of claim 1 further comprising: a plurality of electrodes on a distal portion of the elongate flexible conduit coupled to a controller configured to generate an electrode treatment signal.

20. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal at a frequency of 3Hz.21 . The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal at a frequency between 2.9Hz and 3.1 Hz.

22. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal at a frequency between 2.5Hz and 3.5Hz.

23. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal utilizing a pulse width of 300pS.

24. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal utilizing a pulse width between 290pS and 310pS.

25. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal utilizing a pulse width between 280pS and 320pS.

26. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal from 1mA to 20mA.

27. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal for a 10-m inute duration.

28. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal for a 9 to 11 minute duration.

29. The drainage device of claim 19, wherein the controller is configured to generate the electrode treatment signal for an 8 to 12 minute duration.

30. The drainage device of claim 19, wherein the controller is configured to modify the electrode treatment signal based on an audio feedback signal from an audio sensor indicative of soundwaves generated by the pharynx.31 . The drainage device of claim 19, wherein the controller is configured to modify the electrode treatment signal based on a physiological feedback signal from an EMG sensor indicative of electrical activity in the pharyngeal muscles.

32. A device for treating dysphagia comprising: an elongate flexible conduit comprising a proximal end opening, a distal end opening and a lumen disposed therebetween; and a plurality of electrodes on a distal portion of the elongate flexible conduit coupled to a controller configured to generate an electrode treatment signal.

33. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal at a frequency of 3Hz.

34. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal at a frequency between 2.9Hz and 3.1 Hz.

35. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal at a frequency between 2.5Hz and 3.5Hz.

36. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal utilizing a pulse width of 300pS.

37. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal utilizing a pulse width between 290pS and 310pS.

38. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal utilizing a pulse width between 280pS and 320pS.

39. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal from 1mA to 20mA.

40. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal for a 10-m inute duration.41 . The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal for a 9 to 11 minute duration.

42. The drainage device of claim 32, wherein the controller is configured to generate the electrode treatment signal for an 8 to 12 minute duration.

43. The drainage device of claim 32, wherein the controller is configured to modify the electrode treatment signal based on an audio feedback signal from an audio sensor indicative of soundwaves generated by the pharynx.

44. The drainage device of claim 32, wherein the controller is configured to modify the electrode treatment signal based on a physiological feedback signal from an EMG sensor indicative of electrical activity in the pharyngeal muscles.

45. A method for treating dysphagia comprising: advancing a plurality of electrodes into the posterior pharynx; and delivering electrical stimulation from 1 mA to 20mA to the pharyngeal muscles, at a frequency between 2.5Hz and 3.5Hz and pulse width between 280pS and 320pS.

46. The method of claim 45, wherein the frequency is 3Hz.

47. The method of claim 45, wherein the frequency is between 2.9Hz and 3.1 Hz.

48. The method of claim 45, wherein the pulse width is 300pS.

49. The method of claim 45, wherein the pulse width is between 290pS and 310pS.

50. The method of claim 45, wherein the treatment duration is 10 minutes.51 . The method of claim 45, wherein treatment duration is 9 to 11 minutes.

52. The method of claim 45, wherein the treatment duration is 8 to 12 minutes.

53. The method of claim 45 further comprising: modifying the electrode treatment signal based on an audio feedback signal from an audio sensor indicative of soundwaves generated by the pharynx.

54. The method of claim 45 further comprising: modifying the electrode treatment signal based on a physiological feedback signal from an EMG sensor indicative of electrical activity in the pharyngeal muscles.

55. A drainage device comprising: an elongate flexible conduit comprising a proximal end opening, a distal end opening and a lumen disposed therebetween; anda plurality of liquid crystal polymer electrodes on a distal portion of the elongate flexible conduit coupled to a controller configured to generate an electrode treatment signal.

Images