Bacteriophage compositions for treating Clostridium perfringens infections

JP2024516120A5Pending Publication Date: 2025-04-14アパロン エルティーディー
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Patent Information

Application Number
JP2023562277
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2021-04-09
Filing Date
2022-04-08
Publication Date
2025-04-14

AI Technical Summary

Technical Problem

The widespread use of antibiotics in agriculture to treat and prevent Clostridium perfringens infections in animals leads to antibiotic resistance and disrupts the microbiome, necessitating alternative treatments.

Method used

Development of species-specific lytic bacteriophages and their cocktails that target Clostridium perfringens, capable of lysing bacterial strains and preventing infections without collateral damage to the microbiome.

Benefits of technology

The bacteriophages effectively treat and prevent Clostridium perfringens infections in animals, including poultry, by specifically targeting and lysing the bacteria, thereby reducing the need for antibiotics and minimizing microbiome disruption.

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Abstract

The present invention relates to the field of phage therapy. More specifically, it relates to providing phages, phage-based compositions and methods for treating or preventing bacterial, particularly Clostridium perfringens, infections in animals, including humans, aquaculture animals and livestock animals. The present invention also relates to the use of said compositions as feed ingredients and biological decontamination agents in feed products and foods for human and animal consumption.
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