Method for inhibiting 4-ethylguaiacol odor
A composition of specific components is used to suppress 4-ethylguaiacol odor in foods and spaces by applying it to the raw materials or as a deodorant, effectively masking the odor through sensory evaluation.
Patent Information
- Application Number
- JP2023113243
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Filing Date
- 2023-07-10
- Publication Date
- 2025-01-23
AI Technical Summary
There is a need to suppress the unpleasant odor of 4-ethylguaiacol in various objects such as foods and spaces where it is present or can be produced.
A composition comprising specific components like (E)-β-damascenone, 2,6-dichlorobenzaldehyde, and others is used to mask or suppress the 4-ethylguaiacol odor by applying them to the object or space, either as an ingredient in the raw material or as a deodorant.
The composition effectively reduces or eliminates the 4-ethylguaiacol odor, providing a masking effect that can be measured through sensory evaluation, applicable to foods, waste, and spaces where the odor is present or can occur.
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Abstract
Description
[Technical field]
[0001] The present invention relates to a technique for suppressing the odor of 4-ethylguaiacol. Specifically, the present invention relates to a method for suppressing the odor of 4-ethylguaiacol. [Background technology]
[0002] There is a demand for the development of a technique for suppressing specific odors, such as unpleasant odors, in foods and other objects. For example, methods for suppressing specific odors by blending various ingredients have been reported. Summary of the Invention [Problem to be solved by the invention]
[0003] An object of the present invention is to provide a technique for suppressing the odor of 4-ethylguaiacol. Specifically, an object of the present invention is to provide a method for suppressing the odor of 4-ethylguaiacol. [Means for solving the problem]
[0004] Means for Solving the Problems The present inventors conducted extensive research to solve the above problems, and as a result, discovered various components that suppress the odor of 4-ethylguaiacol, thereby completing the present invention.
[0005] That is, the present invention can be exemplified as follows. [1] 1. A composition for suppressing the odor of 4-ethylguaiacol in a subject, comprising: A composition comprising the following component (A): (A)(E)-At least one component selected from the group consisting of β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and 2,6-dimethylthiophenol. [2] The composition (specifically, the composition described in [1]) wherein the target is an object or a space. [3] The composition (specifically, the composition described in [2]) wherein the item is food or waste. [4] A composition for the manufacture of an article, comprising: A composition comprising the following component (A): (A)(E)-β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol At least one component selected from the group consisting of benzoyl, β-caryophyllene, and 2,6-dimethylthiophenol. [5] The composition (specifically, the composition described in [4]) wherein the article is a food product. [6] The composition (specifically, the composition described in [4] or [5]) above, wherein the article is an article in which the odor of 4-ethylguaiacol is suppressed. [7] The composition (specifically, the composition according to any one of [2] to [6]) wherein the article contains 4-ethylguaiacol and / or a component capable of producing 4-ethylguaiacol. [8] 1. A method for inhibiting the odor of 4-ethylguaiacol in a subject, comprising: The method comprises the step of applying component (A) to the subject: (A)(E)-At least one component selected from the group consisting of β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and 2,6-dimethylthiophenol. [9] The method (specifically, the method described in [8]) above, wherein the object is an object or a space.
[10] The method (specifically, the method described in [9]) above, wherein the item is food or waste.
[11] The object is an article, The article is a food product, The method (specifically, the method described in [8]) wherein the step is a step of adding the component (A) to a raw material of the article.
[12] 1. A method of manufacturing an article, comprising the steps of: The method includes the step of adding component (A) to a raw material of the article: (A)(E)-At least one component selected from the group consisting of β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and 2,6-dimethylthiophenol.
[13] The method (specifically, the method described in
[12] ) above, wherein the item is a food product.
[14] The method (specifically, the method described in
[12] or
[13] ) above, wherein the article is an article in which the odor of 4-ethylguaiacol is suppressed.
[15] The method (specifically, the method described in any one of [9] to
[14] ) wherein the article or the raw material contains 4-ethylguaiacol and / or a component capable of producing 4-ethylguaiacol.
[16] The method (specifically, the method described in any one of [9] to
[15] ) in which the component (A) is added so that the content in the article is 0.01 ppt (w / w) to 1000 ppm (w / w).
[17] The article is a food product, The method (specifically, the method described in
[16] ) above, wherein the content is an intake concentration. Effect of the Invention
[0006] According to the present invention, the odor of 4-ethylguaiacol can be suppressed. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
[0007] The present invention will be described in detail below.
[0008] <1> Active ingredients In order to suppress the odor of 4-ethylguaiacol, the following component (A) is used as an active ingredient: (A)(E)-At least one component selected from the group consisting of β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and 2,6-dimethylthiophenol.
[0009] As component (A), one kind of component may be used, or two or more kinds of components may be used in combination. The combination of components selected as component (A) is not particularly limited.
[0010] Ingredient (A) is also referred to as the "active ingredient."
[0011] By using the active ingredient, the odor of 4-ethylguaiacol can be suppressed, that is, the effect of suppressing the odor of 4-ethylguaiacol can be obtained. This effect is also called "masking effect". "Suppression of 4-ethylguaiacol odor" is also called "reduction of 4-ethylguaiacol odor" or "masking of 4-ethylguaiacol odor". "Suppression of 4-ethylguaiacol odor" includes both the suppression of 4-ethylguaiacol odor that may occur in the future and the suppression of 4-ethylguaiacol odor that has already occurred. "Suppression of 4-ethylguaiacol odor" also includes the complete disappearance of the odor of 4-ethylguaiacol. "Odor" may mean retronasal aroma (i.e., the odor felt from the throat to the nasal cavity when eating the product) and / or orthonasal aroma (i.e., the odor smelled directly from the nose). Specifically, by using the active ingredient, the odor of 4-ethylguaiacol can be suppressed compared to when the active ingredient is not used. Therefore, the masking effect is the same as when the active ingredient is used and when the active ingredient is not used. This can be determined by measuring and comparing the odor. That is, if the intensity of the 4-ethylguaiacol odor when the active ingredient is used is smaller than when the active ingredient is not used, it can be determined that a masking effect has been obtained. The measurement and comparison of the 4-ethylguaiacol odor can be performed, for example, by sensory evaluation by a specialist panel.
[0012] Specifically, the use of the active ingredient can suppress the odor of 4-ethylguaiacol in a subject. The subject is not particularly limited as long as it is desired to suppress the odor of 4-ethylguaiacol.
[0013] The target may be an article. The article may already have a 4-ethylguaiacol odor, or may be capable of having a 4-ethylguaiacol odor in the future. An example of an article that already has a 4-ethylguaiacol odor is an article that contains 4-ethylguaiacol. An example of an article that may have a 4-ethylguaiacol odor in the future is an article that contains a component that can produce 4-ethylguaiacol. That is, the article may contain a component that can produce 4-ethylguaiacol and / or 4-ethylguaiacol. For example, the article may contain a material that contains a component that can produce 4-ethylguaiacol and / or 4-ethylguaiacol, thereby containing a component that can produce 4-ethylguaiacol and / or 4-ethylguaiacol. An example of a component that can produce 4-ethylguaiacol is ferulic acid.
[0014] The article includes food. The food also includes beverages. The food also includes seasonings. The food may be, for example, liquid or solid. Examples of foods containing 4-ethylguaiacol and / or components capable of producing 4-ethylguaiacol include wine and foods containing it. The food is not limited to general foods, but also includes so-called health foods or medical foods such as nutritional supplements, nutritional functional foods, and foods for specified health uses. That is, for example, the foods exemplified above may be provided as general foods, or as health foods or medical foods.
[0015] The article also includes waste. The waste may be, for example, a solid or a liquid (i.e., waste liquid). The waste includes waste discharged from a facility where 4-ethylguaiacol may be generated. Such facilities include facilities that handle articles containing 4-ethylguaiacol and / or components that may generate 4-ethylguaiacol, and facilities that perform operations that generate 4-ethylguaiacol and / or components that may generate 4-ethylguaiacol. The waste also includes discarded food. The food is as described above.
[0016] The target also includes spaces. Spaces include spaces in facilities where 4-ethylguaiacol may be produced (specifically, spaces inside and around such facilities). Facilities where 4-ethylguaiacol may be produced are as described above.
[0017] As the active ingredient, a commercially available product may be used, or one obtained by appropriate production may be used. The method for producing the active ingredient is not particularly limited. The active ingredient can be produced, for example, by chemical synthesis, enzyme reaction, fermentation, extraction, or a combination thereof. The active ingredient may be purified to a desired degree or may not be purified. That is, as the active ingredient, a purified product may be used, or a material containing the active ingredient may be used. As the active ingredient, for example, a material having an active ingredient content of 1% (w / w) or more, 5% (w / w) or more, 10% (w / w) or more, 30% (w / w) or more, 50% (w / w) or more, 70% (w / w) or more, 90% (w / w) or more, or 95% (w / w) or more may be used.
[0018] The amount of active ingredient (e.g. content (concentration) or amount used) is determined by the material containing the active ingredient. When used, it is to be calculated based on the amount of active ingredient itself in the material.
[0019] <2> Compositions of the Invention The composition of the present invention is a composition that contains an active ingredient.
[0020] That is, the composition of the present invention is a composition containing the following component (A): (A)(E)-At least one component selected from the group consisting of β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and 2,6-dimethylthiophenol.
[0021] By utilizing the composition of the present invention, the odor of 4-ethylguaiacol can be suppressed, that is, a masking effect is obtained. Thus, the composition of the present invention may be used to suppress the odor of 4-ethylguaiacol. That is, the composition of the present invention may be, for example, a composition for suppressing the odor of 4-ethylguaiacol. Specifically, the composition of the present invention may be, for example, a composition for suppressing the odor of 4-ethylguaiacol in a target. Specifically, the composition of the present invention may be, for example, a composition for suppressing the odor of 4-ethylguaiacol in an item such as food or waste. Specifically, the composition of the present invention may be, for example, a composition for suppressing the odor of 4-ethylguaiacol in a space.
[0022] Furthermore, by utilizing the composition of the present invention, it is possible to manufacture articles such as food in which the odor of 4-ethylguaiacol is suppressed. Thus, the composition of the present invention may be utilized in the manufacture of articles such as food (specifically, the manufacture of articles such as food in which the odor of 4-ethylguaiacol is suppressed). That is, the composition of the present invention may be, for example, a composition for the manufacture of articles such as food (specifically, the manufacture of articles such as food in which the odor of 4-ethylguaiacol is suppressed).
[0023] The composition of the present invention may be, for example, a seasoning. Specifically, the composition of the present invention may be, for example, a seasoning for suppressing the 4-ethylguaiacol odor in food, or a seasoning for food production (specifically, production of food with suppressed 4-ethylguaiacol odor).
[0024] The composition of the present invention may be, for example, a deodorant. The composition of the present invention may be, specifically, for example, a deodorant for suppressing the 4-ethylguaiacol odor in an object. The composition of the present invention may be, more specifically, for example, a deodorant for suppressing the 4-ethylguaiacol odor in an item such as waste. The composition of the present invention may be, more specifically, for example, a deodorant for suppressing the 4-ethylguaiacol odor in a space. "A deodorant for suppressing the 4-ethylguaiacol odor in an object (e.g., an item or space)" may mean a deodorant for suppressing the 4-ethylguaiacol odor used for an object (e.g., an item or space).
[0025] The composition of the present invention may be used to suppress the odor of 4-ethylguaiacol or to produce articles such as food, in the manner described in the method of the present invention below.
[0026] The composition of the present invention may be composed of an active ingredient, or may contain ingredients other than the active ingredient. The composition of the present invention may exclude a composition composed of an active ingredient. As the ingredient other than the active ingredient, one kind of ingredient may be used, or two or more kinds of ingredients may be used in combination.
[0027] Ingredients other than the active ingredient are not particularly limited as long as they do not impair the masking effect. Ingredients other than the active ingredient can be appropriately selected according to various conditions such as the usage mode of the active ingredient. Ingredients other than the active ingredient include ingredients that are mixed into food or medicine. Specific examples of ingredients other than the active ingredient include the food ingredients described below.
[0028] The composition of the present invention can be produced, for example, by appropriately mixing the active ingredient and, optionally, other ingredients.
[0029] The composition of the present invention may be, for example, appropriately formulated. In the formulation, additives may be appropriately used. Examples of additives include excipients, binders, disintegrants, lubricants, stabilizers, flavorings, diluents, surfactants, and solvents. Additives can be appropriately selected according to various conditions such as the shape of the composition of the present invention.
[0030] The shape of the composition of the present invention is not particularly limited. The composition of the present invention may be in any shape, such as a powder, a flake, a tablet, a paste, or a liquid.
[0031] The content and content ratio of each component (i.e., active ingredient and optional other components) in the composition of the present invention are not particularly limited as long as the masking effect can be obtained.The content and content ratio of each component in the composition of the present invention can be appropriately set according to various conditions such as the use mode of the composition of the present invention.
[0032] The content of the active ingredient in the composition of the present invention is more than 0% (w / w) and 100% (w / w) or less. The content of the active ingredient in the composition of the present invention is, for example, 1 ppt (w / w) or more, 10 ppt (w / w) or more, 100 ppt (w / w) or more, 1 ppb (w / w) or more, 10 ppb (w / w) or more, 100 ppb (w / w) or more, 1 ppm (w / w) or more, 10 ppm (w / w) or more, 100 ppm (w / w) or more, 1000 ppm (w / w) or more, 1% (w / w) or more, 2% (w / w) or more, 5% (w / w) or more, or 10% (w / w) or more. or may be up to 100% (w / w), less than 100% (w / w), up to 99.9% (w / w), up to 90% (w / w), up to 50% (w / w), up to 20% (w / w), up to 10% (w / w), up to 5% (w / w), up to 2% (w / w), up to 1% (w / w), up to 1000 ppm (w / w), up to 100 ppm (w / w), up to 10 ppm (w / w), or up to 1 ppm (w / w), or any combination thereof that is not contradictory. The content of the active ingredient in the composition of the present invention may be, for example, 1 ppt (w / w) to 1 ppm (w / w), 1 ppm (w / w) to 10 ppm (w / w), 10 ppm (w / w) to 100 ppm (w / w), 100 ppm (w / w) to 1000 ppm (w / w), 1000 ppm (w / w) to 1% (w / w), 1% (w / w) to 10% (w / w), or 10% (w / w) to 20% (w / w). The content of the active ingredient in the composition of the present invention may be, for example, 1 ppt (w / w) to 10% (w / w), 1 ppt (w / w) to 1% (w / w), or 1 ppt (w / w) to 1000 ppm (w / w). When the composition of the present invention contains two or more active ingredients, the contents of those two or more active ingredients in the composition of the present invention may be set independently or in total within the range of the contents of the active ingredients in the composition of the present invention exemplified above (however, the total content of those two or more active ingredients in the composition of the present invention is 100% (w / w) or less). When the composition of the present invention contains two or more active ingredients, the "active ingredients in the composition of the present invention" is not limited to the above. Unless otherwise specified, the term "content of active ingredients" refers to the total content of those two or more active ingredients in the composition of the present invention.
[0033] The content of each component (i.e., the active ingredient and optionally other ingredients) in the composition of the present invention can be set, for example, so as to obtain the amount of each component added in the method of the present invention described below.
[0034] The content of each component (i.e., active ingredient and optionally other components) in the composition of the present invention can be set so as to obtain the use concentration of each component in the method of the present invention described below. The use concentration of each component may be the concentration when the composition of the present invention is used in the form of a liquid. The use concentration of the active ingredient in the method of the present invention includes the concentration of the active ingredient in the solution containing the active ingredient used in the method of the present invention.
[0035] Each component (i.e., active ingredient and optional other components) contained in the composition of the present invention may be mixed together and contained in the composition of the present invention, or may be contained separately or in any combination in the composition of the present invention.For example, the composition of the present invention may be provided as a set of each component packaged separately.In such a case, the components contained in the set can be used together as appropriate when used.
[0036] <3> Methods of the Invention The method of the present invention is a method which comprises the step of utilizing an active ingredient.
[0037] That is, the method of the present invention is a method comprising the step of utilizing the following component (A): (A)(E)-At least one component selected from the group consisting of β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and 2,6-dimethylthiophenol.
[0038] The method of the present invention, specifically by utilizing the active ingredient, can suppress the 4-ethylguaiacol odor, that is, a masking effect is obtained. Thus, the method of the present invention may be carried out to suppress the 4-ethylguaiacol odor. That is, the method of the present invention may be, for example, a method for suppressing the 4-ethylguaiacol odor. The method is also referred to as the "masking method of the present invention". The method of the present invention may be, specifically, for example, a method for suppressing the 4-ethylguaiacol odor in a subject. The method of the present invention may be, more specifically, for example, a method for suppressing the 4-ethylguaiacol odor in an item such as food or waste. The method of the present invention may be, more specifically, for example, a method for suppressing the 4-ethylguaiacol odor in a space.
[0039] Furthermore, the method of the present invention, specifically by utilizing the active ingredient, can produce an article such as food in which the odor of 4-ethylguaiacol is suppressed. Thus, the method of the present invention may be carried out for producing an article such as food (specifically, producing an article such as food in which the odor of 4-ethylguaiacol is suppressed). That is, the method of the present invention may be, for example, a method for producing an article such as food (specifically, producing an article such as food in which the odor of 4-ethylguaiacol is suppressed). This method is also referred to as the "production method of the present invention."
[0040] The active ingredient can be used to suppress the odor of 4-ethylguaiacol in a target by applying it to the target. That is, use of the active ingredient includes applying the active ingredient to the target.
[0041] For example, the active ingredient can be used to suppress the 4-ethylguaiacol odor or to manufacture an article such as food by adding it to the raw materials of the article such as food during the manufacture of the article such as food. That is, the use of the active ingredient (specifically, the application of the active ingredient to a target) can include adding the active ingredient to the raw materials of the article such as food. That is, the method of the present invention can be specifically, for example, a method for suppressing the 4-ethylguaiacol odor in an article such as food, which includes adding the active ingredient to the raw materials of the article such as food. In addition, the method of the present invention can be specifically, for example, a method for manufacturing an article such as food (specifically, a method for manufacturing an article such as food in which the 4-ethylguaiacol odor is suppressed), which includes adding the active ingredient to the raw materials of the article such as food. "Addition" is also called "blending".
[0042] The active ingredient may be utilized in the method of the present invention, for example, in the form of a composition of the present invention. That is, "utilization of an active ingredient" also includes utilization of a composition of the present invention. For example, "addition of an active ingredient" also includes addition of a composition of the present invention.
[0043] The article obtained by the method of the present invention is also called the "article of the present invention". For example, the food obtained by the method of the present invention is also called the "food of the present invention". Specifically, the article of the present invention is an article in which the odor of 4-ethylguaiacol is suppressed. In other words, the article of the present invention is an article to which an active ingredient is added.
[0044] The suppression of the 4-ethylguaiacol odor or the manufacture of the article may be carried out in the same manner as the manufacture of a normal article, except for the use of an active ingredient. That is, the suppression of the 4-ethylguaiacol odor or the manufacture of the article may be carried out using the same raw materials as normal articles under the same manufacturing conditions, except for the use of an active ingredient. In addition, the raw materials and manufacturing conditions of the article may be appropriately modified and used for the suppression of the 4-ethylguaiacol odor or the manufacture of the article.
[0045] The manner in which the article is provided is not particularly limited. The article may be provided, for example, in a form that can be used as is, or in a form that requires preparation when used. As an example, the food may be provided, for example, in a form that can be eaten as is, or in a form that requires preparation before or at the time of eating, such as a concentrated product or a dried product. The article may also be provided in any container, such as a retort pouch, a paper pack, a plastic bottle such as a PET bottle, a metal can such as a steel can or an aluminum can, or a glass bottle.
[0046] "Raw material for an article" means a material for manufacturing an article. For example, "raw material for a food" means a food material for manufacturing a food. The raw material for an article is not particularly limited as long as the article can be manufactured. The raw material for an article can be appropriately selected according to various conditions such as the type of the article. As an example, the raw material for a food can be a raw material that can be normally used in manufacturing a food. Specific examples of the raw material for a food include grains such as wheat flour; seasoning ingredients such as sugar, inorganic salts, organic acids, nucleic acids, amino acids, and protein hydrolysates; dairy products such as milk, cheese, and butter; fruits; vegetables; eggs; spices; flavorings; fats and oils; alcohol; dietary fiber; and pH buffers.
[0047] The active ingredient may be added to the raw material of the article at any stage in the manufacturing process of the article, so long as the masking effect is obtained. In other words, the "raw material of the article" to which the active ingredient is added may be at any stage in the manufacturing process of the article. For example, the "raw material of the article" to which the active ingredient is added may include a finished article before the active ingredient is added. The component can be added to the raw material of the article as it is, or after preparing it into a desired form such as a solution. For example, the active ingredient in any form such as a solution may be mixed with the raw material of the article, a solution containing the active ingredient may be sprayed onto the raw material of the article, or the raw material of the article may be immersed in a solution containing the active ingredient. "Addition of an active ingredient" may collectively refer to an operation in which an active ingredient coexists with the raw material of the article. Components other than the active ingredient (e.g., 4-ethylguaiacol or components that can produce 4-ethylguaiacol) may also be added to the raw material of the article as appropriate. The description of the addition of an active ingredient can also be applied mutatis mutandis to the addition of components other than the active ingredient. Each component (i.e., the active ingredient and optionally other components) may be added to the raw material of the article all at the same time, or each may be added separately, or each may be added separately in any combination to the raw material of the article. The order in which each component is added to the raw material of the article is not particularly limited.
[0048] The amount and ratio of each component (i.e., active ingredient and optional other components) added in the method of the present invention are not particularly limited as long as the masking effect can be obtained. The amount and ratio of each component added in the method of the present invention can be appropriately set according to various conditions such as the type of raw material of the product and the type of the product.
[0049] The active ingredient may be added to the raw material of the product, for example, so that the content of the active ingredient in the product is within a desired range. As an example, the active ingredient may be added to the raw material of a food product, for example, so that the ingestible concentration of the active ingredient is within a desired range (for example, the ingestible concentration range of the active ingredient described below).
[0050] The content of the active ingredient in the product (e.g., ingestible concentration) is, for example, 0.01 ppt (w / w) or more. , 0.02 ppt(w / w) or more, 0.05 ppt(w / w) or more, 0.1 ppt(w / w) or more, 0.2 ppt(w / w) or more, 0.5 ppt(w / w) or more, 1 ppt(w / w) or more, 2 ppt(w / w) or more, 5 ppt(w / w) or more, 10 ppt(w / w) or more, 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 100 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, 50 ppm(w / w) or more, 100 ppm(w / w) or more, 200 ppm(w / w) or more, or 500 ppm(w / w) or more May be present, but not exceeding 1000 ppm (w / w), 500 ppm (w / w), 200 ppm (w / w), 100 ppm (w / w), 50 ppm (w / w), 20 ppm (w / w), 10 ppm (w / w), 5 ppm (w / w), 2 ppm (w / w), 1 ppm (w / w), 500 ppb (w / w), 200 ppb (w / w), 100 ppb (w / w), 50 ppb (w / w), 20 ppb (w / w), 10 ppb (w / w), 5 ppb (w / w), 2 ppb (w / w) or less, 1 ppb(w / w), 500 ppt(w / w), 200 ppt(w / w), 100 ppt(w / w), 50 ppt(w / w), 20 ppt(w / w), 10 ppt(w / w), 5 ppt(w / w), 2 ppt(w / w), 1 ppt(w / w), 0.5 ppt(w / w), 0.2 ppt(w / w), 0.1 ppt(w / w), 0.05 ppt(w / w), or 0.02 ppt(w / w), or any combination thereof that is not inconsistent. The content of the active ingredient in the article (e.g., ingestible concentration) may be, specifically, for example, 0.01 ppt (w / w) to 0.02 ppt (w / w), 0.02 ppt (w / w) to 0.05 ppt (w / w), 0.05 ppt (w / w) to 0.1 ppt(w / w), 0.1 ppt(w / w)~0.2 ppt(w / w), 0.2 ppt(w / w)~0.5 ppt(w / w), 0.5 ppt(w / w) ~1 ppt(w / w), 1 ppt(w / w)~2 ppt(w / w), 2 ppt(w / w)~5 ppt(w / w), 5 ppt(w / w)~10 ppt(w / w), 10 ppt(w / w)~20 ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w) , 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w) , 100 ppb(w / w) to 200 ppb(w / w), 200 ppb(w / w) to 500 ppb(w / w), 500 ppb(w / w) to 1 ppm(w / w), 1 ppm(w / w) to 2 ppm(w / w), 2 ppm(w / w) to 5 ppm(w / w), 5 ppm(w / w) to 10 ppm(w / w), 10 ppm(w / w) to 20 ppm(w / w), 20 ppm(w / w) to 50 ppm(w / w), 50 ppm(w / w) to 100 ppm(w / w), 100 ppm(w / w) to 200 ppm(w / w), 200 ppm(w / w) to 500 ppm(w / w), or 500 ppm(w / w) to 1000 ppm(w / w). The content of the active ingredient in the product (e.g., the concentration to be consumed) may be, for example, 0.01 ppt (w / w) to 1000 ppm (w / w). The content (e.g., ingested concentration) of the active ingredient in the above-exemplified article can be applied to any active ingredient. When the article contains two or more active ingredients, the content (e.g., ingested concentration) of the two or more active ingredients in the article may be set to the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article, independently or in total. When the article contains two or more active ingredients, the "content of the active ingredient in the article" means the total content of the two or more active ingredients in the article, unless otherwise specified. When the food contains two or more active ingredients, the "ingested concentration of the active ingredient" means the total ingested concentration of the two or more active ingredients in the food, unless otherwise specified.
[0051] The content of ethyl mercaptoacetate in the article (e.g., ingested concentration) may be, for example, in the range of the content of the active ingredient in the above-exemplified article (e.g., ingested concentration). The content of ethyl mercaptoacetate in the article (e.g., ingested concentration) may be, for example, 0.01 ppt (w / w) or more, 0.02 ppt (w / w) or more, 0.05 ppt (w / w) or more, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, or more, 0.5 ppt(w / w) or more, 1 ppt(w / w) or more, 2 ppt(w / w) or more, 5 ppt(w / w) or more, 10 ppt(w / w) or more, 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, or 5 ppb(w / w) or more and may be 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, 200 ppt (w / w) or less, 100 ppt (w / w) or less, 50 ppt (w / w) or less, 20 ppt (w / w) or less, 10 ppt (w / w) or less, 5 ppt (w / w) or less, 2 ppt (w / w) or less, 1 ppt (w / w) or less, 0.5 ppt (w / w) or less, 0.2 ppt (w / w) or less, 0.1 ppt (w / w) or less, 0.05 ppt (w / w) or less, or 0.02 ppt (w / w) or less, or any non-consistent combination thereof. The content of ethyl mercaptoacetate in the article (e.g., ingestion concentration) is specifically, for example, 0.01 ppt(w / w) to 0.02 ppt(w / w), 0.02 ppt(w / w) to 0.05 ppt(w / w), 0.05 ppt(w / w) to 0.1 ppt(w / w), 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) It may be up to 20 ppt(w / w), 20 ppt(w / w)-50 ppt(w / w), 50 ppt(w / w)-100 ppt(w / w), 100 ppt(w / w)-200 ppt(w / w), 200 ppt(w / w)-500 ppt(w / w), 500 ppt(w / w)-1 ppb(w / w), 1 ppb(w / w)-2 ppb(w / w), 2 ppb(w / w)-5 ppb(w / w), or 5 ppb(w / w)-10 ppb(w / w). The content of ethyl mercaptoacetate in the article (e.g., ingestible concentration) may be specifically, for example, 0.01 ppt (w / w) to 10 ppb (w / w), 0.1 ppt (w / w) to 1 ppb (w / w), or 1 ppt (w / w) to 100 ppt (w / w).
[0052] The content (e.g., ingested concentration) of (3R / 3S)-3-sulfanylpentan-2-one in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. The content (e.g., ingested concentration) of (3R / 3S)-3-sulfanylpentan-2-one in the article may be, for example, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, 0.5 ppt (w / w) or more, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, or 200 ppt (w / w) or more. , 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb (w / w) or more, or 50 ppb (w / w) or more, but may be 100 ppb (w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less , 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, 2 ppt(w / w) or less, 1 ppt(w / w) or less, 0.5 ppt(w / w) or less, or 0.2 ppt(w / w) or less, or any inconsistency therebetween. The content of (3R / 3S)-3-sulfanylpentan-2-one in the article (e.g., ingestible concentration) is specifically, for example, 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt (w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w) , 20 ppb (w / w) to 50 ppb (w / w), or 50 ppb (w / w) to 100 ppb (w / w). The content of (3R / 3S)-3-sulfanylpentan-2-one in the food product (e.g., ingestible concentration) may be specifically, for example, 0.1 ppt (w / w) to 100 ppb (w / w), 1 ppt (w / w) to 10 ppb (w / w), or 10 ppt (w / w) to 1 ppb (w / w).
[0053] The content of phloretin in the article (e.g., ingested concentration) may be, for example, in the range of the content of the active ingredient in the above-mentioned example article (e.g., ingested concentration). The content of phloretin in the article (e.g., ingested concentration) may be, for example, 0.1 ppt (w / w) or more, 0.2 ppt (w / w) or more, 0.5 ppt (w / w) or more, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, or 200 ppt (w / w) or more. , 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, or 5 ppm(w / w) or more, and may be 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb (w / w) or less, 100 ppb (w / w) or less, 50 ppb (w / w) or less, 20 ppb (w / w) or less, 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w), 200 ppt (w / w), or less, 100 ppt (w / w), or less, 50 ppt (w / w), or less, 20 ppt (w / w), or less, 10 ppt (w / w), or less, 5 ppt (w / w), or less, 2 ppt (w / w), or less, 1 ppt (w / w), or less, 0.5 ppt (w / w), or less, or 0.2 ppt (w / w), or any combination thereof that is not contradictory. The content of phloretin in the article (e.g., ingestible concentration) is specifically, for example, 0.1 ppt(w / w) to 0.2 ppt(w / w), 0.2 ppt(w / w) to 0.5 ppt(w / w), 0.5 ppt(w / w) to 1 ppt(w / w), 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 It may be from ppm (w / w) to 5 ppm (w / w), or from 5 ppm (w / w) to 10 ppm (w / w). The phloretin content (e.g., ingested concentration) may be specifically, for example, 0.1 ppt (w / w) to 10 ppm (w / w), 1 ppt (w / w) to 1 ppm (w / w), or 10 ppt (w / w) to 100 ppb (w / w).
[0054] The content (eg, ingested concentration) of hinokitiol or 2-methyl-3-furanthiol in the article may be, for example, within the range of the content (eg, ingested concentration) of the active ingredient in the above-exemplified articles. The content (e.g., ingestion concentration) of hinokitiol or 2-methyl-3-furanthiol in the article may be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, or 500 ppb (w / w) or more; ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, unless inconsistent therewith. The content (e.g., ingestible concentration) of hinokitiol or 2-methyl-3-furanthiol in the article is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), ), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 The content (e.g., ingestible concentration) of hinokitiol or 2-methyl-3-furanthiol in the article may be, for example, 1 ppt(w / w) to 1 ppm(w / w), 10 ppt(w / w) to 100 ppb(w / w), or 500 ppb(w / w) to 1 ppm(w / w). or 100 ppt(w / w) to 10 ppb(w / w).
[0055] The content (eg, ingestible concentration) of β-naphthyl anthranilate in the article may be, for example, within the range of the content (eg, ingestible concentration) of the active ingredient in the above-exemplified articles. The content of β-naphthyl anthranilate in the article (e.g., ingestible concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 ppb (w / w) or more, 1 ppm (w / w) or more, 2 It may be ppm (w / w) or more, or 5 ppm (w / w) or more, and may be 10 ppm (w / w) or less, 5 ppm (w / w) or less, 2 ppm (w / w) or less, 1 ppm (w / w) or less, 500 ppb (w / w) or less, 200 ppb (w / w) or less, 100 ppb (w / w) or less, 50 ppb (w / w) or less, 20 ppb (w / w) or less, 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, 200 ppt (w / w) or less, 100 ppt (w / w) or less, 50 ppt (w / w) or less, 20 ppt (w / w) or less, 10 ppt (w / w) or less, 5 ppt (w / w) or less, or 2 ppt(w / w) or less, or any compatible combination thereof. The content of β-naphthyl anthranilate (e.g., ingestible concentration) in the food product is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w) to 10 ppb(w / w), 10 ppb(w / w) to 20 ppb(w / w), 20 ppb(w / w) to 50 ppb(w / w), 50 ppb(w / w) to 100 ppb(w / w), 100 ppb(w / w) to 200 ppb(w / w), 200 ppb(w / w) to 500 ppb(w / w), 500 ppb(w / w) to 1 ppm(w / w), 1 ppm(w / w) to 2 ppm(w / w), 2 ppm(w / w) to 5 ppm(w / w), or 5 ppm(w / w) to 10 ppm(w / w). The content of β-naphthyl anthranilate in the article (e.g., ingestible concentration) may be specifically, for example, 1 ppt (w / w) to 10 ppm (w / w), 10 ppt (w / w) to 1 ppm (w / w), or 100 ppt (w / w) to 100 ppb (w / w).
[0056] The content (e.g., ingested concentration) of trans-resveratrol in the product may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified product. The content (e.g., ingested concentration) of trans-resveratrol in the product may be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, or 500 ppt (w / w) or more. , 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, or or more than 50 ppm (w / w), and may be 100 ppm (w / w), or less, 50 ppm (w / w), or less, 20 ppm (w / w), or less, 10 ppm (w / w), or less, 5 ppm (w / w), or less, 2 ppm (w / w), or less, 1 ppm (w / w), or less, 500 ppb (w / w), or less, 200 ppb (w / w), or less, 100 ppb (w / w), or less, 50 ppb (w / w), or less, 20 ppb (w / w), or less, 10 ppb (w / w), or less, 5 ppb (w / w), or less, 2 ppb (w / w), or less, 1 ppb (w / w), or less, 500 ppt (w / w). or less, 200 ppt(w / w), 100 ppt(w / w), 50 ppt(w / w), 20 ppt(w / w), 10 ppt(w / w), 5 ppt(w / w), or 2 ppt(w / w), provided there are no inconsistencies between these. The content of trans-resveratrol in the article (e.g., ingestible concentration) is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), or any combination thereof. t(w / w), 5 ppt(w / w)~10 ppt(w / w), 10 ppt(w / w)~20 ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 It may be ppb(w / w)-50 ppb(w / w), 50 ppb(w / w)-100 ppb(w / w), 100 ppb(w / w)-200 ppb(w / w), 200 ppb(w / w)-500 ppb(w / w), 500 ppb(w / w)-1 ppm(w / w), 1 ppm(w / w)-2 ppm(w / w), 2 ppm(w / w)-5 ppm(w / w), 5 ppm(w / w)-10 ppm(w / w), 10 ppm(w / w)-20 ppm(w / w), 20 ppm(w / w)-50 ppm(w / w), or 50 ppm(w / w)-100 ppm(w / w). The content of trans-resveratrol in the product (e.g., ingestible concentration) is specifically, for example, 1 ppt (w / w) to 100 ppm (w / w), 10 It may be from ppt(w / w) to 10 ppm(w / w), or from 100 ppt(w / w) to 1 ppm(w / w).
[0057] The content (e.g., ingested concentration) of methyl isothiocyanate or isobutyl 4-hydroxybenzoate in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. In addition, the content (e.g., ingested concentration) of methyl isothiocyanate or isobutyl 4-hydroxybenzoate in the article may be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 5 ... ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt(w / w) or more, 1 ppb(w / w) or more, 2 ppb(w / w) or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm (w / w) or more, 5 ppm (w / w) or more, 10 ppm (w / w) or more, 20 ppm (w / w) or more, 50 ppm (w / w) or more, 100 ppm (w / w) or more, 200 ppm (w / w) or more, or 500 ppm (w / w) or more, ppm(w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less , 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, The content (e.g., ingestible concentration) of methyl isothiocyanate or isobutyl 4-hydroxybenzoate in the article is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 ppm(w / w)~100 ppm(w / w), 100 ppm(w / w)~200 ppm(w / w), 200 ppm(w / w)~500 ppm(w / w), or 500 ppm(w / w)~1000 ppm(w / w) The content (e.g., ingestible concentration) of methyl isothiocyanate or isobutyl 4-hydroxybenzoate in the article may be, specifically, for example, 1 ppt (w / w) to 1000 ppm (w / w), 10 ppt (w / w) to 100 ppm (w / w), or 100 ppt (w / w) to 10 ppm (w / w). stomach.
[0058] The content (e.g., ingested concentration) of (E)-β-damascenone, allyl isothiocyanate, 1-pentan-3-one, or 2-methylbenzenethiol in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. The content (e.g., ingested concentration) of (E)-β-damascenone, allyl isothiocyanate, 1-pentan-3-one, or 2-methylbenzenethiol in the article may be, for example, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 It may be ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, or 5 ppm(w / w) or more, and may be 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, or 20 ppt(w / w) or less or any non-consistent combination thereof. The content (e.g., ingestible concentration) of (E)-β-damascenone, allyl isothiocyanate, 1-pentan-3-one, or 2-methylbenzenethiol in the article is specifically, for example, 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w) to 10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 The content (e.g., ingested concentration) of (E)-β-damascenone, allyl isothiocyanate, 1-pentan-3-one, or 2-methylbenzenethiol in the article may be, specifically, for example, 10 ppt(w / w) to 10 ppm(w / w), 100 ppt(w / w) to 1 ppm(w / w), or 1 ppb(w / w) to 100 ppb(w / w).
[0059] The content (e.g., ingested concentration) of apigenin or 4-propylphenol in the article may be, for example, in the range of the content (e.g., ingested concentration) of the active ingredient in the above-exemplified article. The content (e.g., ingested concentration) of apigenin or 4-propylphenol in the article may be, for example, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, or more. or more, 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 It may be ppm (w / w) or more, 10 ppm (w / w) or more, 20 ppm (w / w) or more, or 50 ppm (w / w) or more, and may be 100 ppm (w / w) or less, 50 ppm (w / w) or less, 20 ppm (w / w) or less, 10 ppm (w / w) or less, 5 ppm (w / w) or less, 2 ppm (w / w) or less, 1 ppm (w / w) or less, 500 ppb (w / w) or less, 200 ppb (w / w) or less, 100 ppb (w / w) or less, 50 ppb (w / w) or less, 20 ppb (w / w) or less, 10 ppb (w / w) or less, 5 ppb (w / w) or less, 2 ppb (w / w) or less, 1 ppb (w / w) or less, 500 ppt (w / w) or less, 200 ppt (w / w) or less, 100 The content of apigenin or 4-propylphenol in the article (e.g., ingestible concentration) may be, for example, 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w) ~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 The content of apigenin or 4-propylphenol in the article (e.g., ingestible concentration) may be, specifically, for example, 10 ppt(w / w) to 100 ppm(w / w), 100 ppt(w / w) to 10 ppm(w / w), or 1 ppb(w / w) to 1 ppm(w / w).
[0060] The content of propyl gallate in the article (e.g., ingestible concentration) may be, for example, in the range of the content of the active ingredient in the above-exemplified article (e.g., ingestible concentration). In addition, the content of propyl gallate in the article (e.g., ingestible concentration) may be, for example, 10 ppt (w / w) or more. , 20 ppt(w / w) or more, 50 ppt(w / w) or more, 100 ppt(w / w) or more, 200 ppt(w / w) or more, 500 ppt( w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 ppb (w / w) or more or more than 1 ppm (w / w), 2 ppm (w / w), 5 ppm (w / w), 10 ppm (w / w), 20 ppm (w / w), 50 ppm (w / w), 100 ppm (w / w), 200 ppm (w / w), or 500 ppm (w / w) or less, and may be 1000 ppm (w / w), 500 ppm (w / w), 200 ppm (w / w), 100 ppm (w / w), 50 ppm (w / w), 20 ppm (w / w), 10 ppm (w / w), 5 ppm (w / w), 2 ppm (w / w), 1 ppm (w / w), 500 ppb (w / w), 200 ppb (w / w), 100 ppb (w / w), 50 ppb (w / w), 20 ppb (w / w), 10 ppb (w / w), 5 ppb (w / w), 2 ppb (w / w), 1 ppb (w / w), 500 ppt (w / w), 200 ppt (w / w), 100 ppt(w / w) or less, 50 ppt(w / w) or less, or 20 ppt(w / w) or less, or any compatible combination thereof. The content of propyl gallate in the article (e.g., ingestible concentration) may be, for example, 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) ~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 ppm(w / w)~100 The content of propyl gallate in the article (e.g., the amount of propyl gallate consumed) may be 100 ppm (w / w) to 200 ppm (w / w), 200 ppm (w / w) to 500 ppm (w / w), or 500 ppm (w / w) to 1000 ppm (w / w). The concentration) may be specifically, for example, 10 ppt (w / w) to 1000 ppm (w / w), 100 ppt (w / w) to 100 ppm (w / w), or 1 ppb (w / w) to 10 ppm (w / w).
[0061] The content (e.g., ingestible concentration) of 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, N-(4-hydroxy-3-methoxybenzyl)nonanamide, β-caryophyllene, or 2,6-dimethylthiophenol in the article may be, for example, in the range of the content (e.g., ingestible concentration) of the active ingredient in the article exemplified above. In addition, the content (e.g., ingestion concentration) of 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, N-(4-hydroxy-3-methoxybenzyl)nonanamide, β-caryophyllene, or 2,6-dimethylthiophenol in the article is, for example, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, or 50 ppm(w / w) or more, but not more than 100 ppm(w / w). , 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) Below, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, or 200 ppt(w / w) or less, The content (e.g., ingestible concentration) of 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, N-(4-hydroxy-3-methoxybenzyl)nonanamide, β-caryophyllene, or 2,6-dimethylthiophenol in the article is specifically, for example, 100 ppt (w / w) to 200 ppt (w / w), 200 ppt (w / w) to 500 ppt (w / w), 500 ppt (w / w) to 1 ppb (w / w), 1 ppb (w / w) to 2 ppb (w / w), 2 ppb (w / w) to 5 ppb (w / w), 5 ppb (w / w) to 10 ppb (w / w), 10 ppb (w / w) to 20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), or 5 The content (e.g., ingested concentration) of 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, N-(4-hydroxy-3-methoxybenzyl)nonanamide, β-caryophyllene, or 2,6-dimethylthiophenol in the article may be specifically, for example, 100 ppt(w / w) to 100 ppm(w / w), 1 ppb(w / w) to 10 ppm(w / w), or 10 ppb(w / w) to 1 ppm(w / w).
[0062] The content of 2,5-dimethyl-3-furanthiol in the article (eg, ingestible concentration) may be, for example, within the range of the content (eg, ingestible concentration) of the active ingredient in the above-exemplified articles. The content of 2,5-dimethyl-3-furanthiol in the article (e.g., ingestible concentration) may be, for example, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 ppb (w / w) or more, 1 ppm (w / w) or more, 2 ppm (w / w) or more, 5 ppm (w / w) or more, 10 ppm (w / w) or more, 20 ppm (w / w) or more, 50 ppm (w / w) or more, 100 ppm (w / w) or more, 200 ppm (w / w) or more, or 500 ppm (w / w) or more, and may be 1000 ppm (w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm (w / w) or less, 50 ppm (w / w) or less, 20 ppm (w / w) or less, 10 ppm (w / w) or less, 5 ppm (w / w) or less, 2 ppm (w / w) or less, 1 ppm (w / w) or less, 500 ppb (w / w) or less, 200 ppb (w / w) or less, 100 ppb (w / w) or less, 50 ppb (w / w) or less, 20 ppb (w / w) or less, 10 ppb (w / w) or less, 5 ppb (w / w) or less, or 2 ppb (w / w) or less, or any non-consistent combination thereof. The content of 2,5-dimethyl-3-furanthiol in the article (e.g., ingestible concentration) is specifically, for example, 1 ppb (w / w) to 2 ppb (w / w), 2 ppb (w / w) to 5 ppb (w / w), 5 ppb (w / w) to 10 ppb (w / w), 10 ppb (w / w) to 20 ppb (w / w), 20 ppb (w / w) to 50 ppb (w / w), 50 ppb (w / w) to 100 ppb (w / w), 100 ppb (w / w) to 200 ppb (w / w), 200 ppb (w / w) to 500 ppb (w / w), 500 ppb (w / w) to 1 ppm (w / w), 1 ppm (w / w) to 2 ppm (w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 The content of 2,5-dimethyl-3-furanthiola in the article may be 10 ppm (w / w) to 20 ppm (w / w), 20 ppm (w / w) to 50 ppm (w / w), 50 ppm (w / w) to 100 ppm (w / w), 100 ppm (w / w) to 200 ppm (w / w), 200 ppm (w / w) to 500 ppm (w / w), or 500 ppm (w / w) to 1000 ppm (w / w). The content of the alcohol (e.g., ingestible concentration) may be specifically, for example, 1 ppb (w / w) to 1000 ppm (w / w), 10 ppb (w / w) to 100 ppm (w / w), or 100 ppb (w / w) to 10 ppm (w / w).
[0063] The concentration of the active ingredient in the article (e.g., the concentration when consumed) may be, for example, 100 times or less than the threshold concentration of the active ingredient, 10 times or less than the threshold concentration, 5 times or less than the threshold concentration, 2 times or less than the threshold concentration, or less than the threshold concentration. The concentration of the active ingredient in the article (e.g., the concentration when consumed) may be, for example, in the range of the concentration of the active ingredient in the above-mentioned example (e.g., the concentration when consumed), and may be, for example, in the range of 100 times or less than the threshold concentration of the active ingredient, 10 times or less than the threshold concentration, 5 times or less than the threshold concentration, 2 times or less than the threshold concentration, or less than the threshold concentration. The "threshold concentration of the active ingredient" means the maximum concentration of the active ingredient at which the odor of the active ingredient itself is not felt when an aqueous solution containing the active ingredient alone is consumed or sniffed with the nose. The threshold concentration of the active ingredient may be the threshold concentration described in the examples.
[0064] The description of the addition of an active ingredient can be applied mutatis mutandis to the addition of the composition of the present invention. For example, the composition of the present invention can be added so as to obtain the amount of the active ingredient exemplified above.
[0065] Ingredients other than the active ingredient may be added to the raw materials of the product, for example, so that the ingested concentration of the ingredients other than the active ingredient falls within a desired range (for example, the range described below).
[0066] The article of the present invention may contain a component capable of generating 4-ethylguaiacol. That is, the article of the present invention may be manufactured to contain a component capable of generating 4-ethylguaiacol. The article containing a component capable of generating 4-ethylguaiacol may be, for example, 4-ethyl The article can be manufactured using a material containing a component capable of producing 4-ethylguaiacol. That is, the method of the present invention may further include manufacturing an article using a material containing a component capable of producing 4-ethylguaiacol. That is, the raw material of the article can be a material containing a component capable of producing 4-ethylguaiacol. In other words, the raw material of the article may contain a component capable of producing 4-ethylguaiacol. The material containing a component capable of producing 4-ethylguaiacol is as described above.
[0067] When a component capable of generating 4-ethylguaiacol can form a salt, the component capable of generating 4-ethylguaiacol may be used as a free form, as a salt, or as a combination thereof. That is, the term "component capable of generating 4-ethylguaiacol" may mean a component capable of generating 4-ethylguaiacol in free form, or a salt thereof, or a combination thereof, unless otherwise specified. "Free form" means a form that does not form a salt. Also, when a component capable of generating 4-ethylguaiacol can form a hydrate, the component capable of generating 4-ethylguaiacol may be used as a non-hydrate, or a hydrate, or as a combination thereof. That is, the term "component capable of generating 4-ethylguaiacol" (for example, "component capable of generating 4-ethylguaiacol in free form" or "salt of a component capable of generating 4-ethylguaiacol") may include a non-hydrate and a hydrate, unless otherwise specified. The component capable of generating 4-ethylguaiacol may be in any form, such as an ion, when the article is used.
[0068] The salt is not particularly limited as long as it is acceptable according to the purpose of the present invention. For example, when the subject is food, the salt is not particularly limited as long as it is orally ingestible. For example, the salt of an acidic group such as a carboxyl group specifically includes ammonium salts, salts with alkali metals such as sodium and potassium, salts with alkaline earth metals such as calcium and magnesium, aluminum salts, zinc salts, salts with organic amines such as triethylamine, ethanolamine, morpholine, pyrrolidine, piperidine, piperazine, and dicyclohexylamine, and salts with basic amino acids such as arginine and lysine. Furthermore, specific examples of salts with basic groups such as amino groups include salts with inorganic acids such as hydrochloric acid, sulfuric acid, phosphoric acid, nitric acid, and hydrobromic acid, salts with organic carboxylic acids such as acetic acid, citric acid, benzoic acid, maleic acid, fumaric acid, tartaric acid, succinic acid, tannic acid, butyric acid, hybenzic acid, pamoic acid, enanthic acid, decanoic acid, teoclic acid, salicylic acid, lactic acid, oxalic acid, mandelic acid, malic acid, methylmalonic acid, and adipic acid, and salts with organic sulfonic acids such as methanesulfonic acid, benzenesulfonic acid, and p-toluenesulfonic acid. As the salt, one type of salt may be used, or two or more types of salts may be used in combination.
[0069] When a material containing a component capable of producing 4-ethylguaiacol is used, the amount of the component capable of producing 4-ethylguaiacol (e.g., content (concentration) or amount used) is calculated based on the amount of the component itself capable of producing 4-ethylguaiacol in the material. When a component capable of producing 4-ethylguaiacol forms a salt or hydrate, the amount of the component capable of producing 4-ethylguaiacol (e.g., content (concentration) or amount used) is calculated based on the mass of the salt or hydrate converted to the equimolar mass of the unhydrated free form.
[0070] The article of the present invention may contain 4-ethylguaiacol. That is, the article of the present invention may be manufactured so as to contain 4-ethylguaiacol. The article containing 4-ethylguaiacol can be manufactured, for example, by using a material containing 4-ethylguaiacol. That is, the method of the present invention may further include manufacturing the article by using a material containing 4-ethylguaiacol. That is, the raw material of the article may be a material containing 4-ethylguaiacol. In other words, the raw material of the article may be 4-ethylguaiacol. The material may contain ethylguaiacol. The material containing 4-ethylguaiacol is as described above. In addition, 4-ethylguaiacol may be generated, for example, during the manufacturing process of the article of the present invention. In addition, 4-ethylguaiacol may be generated, for example, after the manufacturing process of the article of the present invention is carried out (for example, during storage of the article of the present invention). 4-ethylguaiacol may be generated from a component that can generate 4-ethylguaiacol.
[0071] In addition, when a material containing 4-ethylguaiacol is used, the amount of 4-ethylguaiacol (e.g., content (concentration) or amount used) is to be calculated based on the amount of 4-ethylguaiacol itself in the material.
[0072] When the article of the present invention contains a component capable of generating 4-ethylguaiacol, the content of the component capable of generating 4-ethylguaiacol in the article of the present invention may be, for example, an amount that can generate 4-ethylguaiacol at a level at which a human can detect a 4-ethylguaiacol odor (for example, an ingestion concentration). When the article of the present invention contains two or more components that can generate 4-ethylguaiacol, "the content of the component capable of generating 4-ethylguaiacol in the article of the present invention is an amount that can generate 4-ethylguaiacol at a level at which a human can detect a 4-ethylguaiacol odor (for example, an ingestion concentration)" means that the total amount of 4-ethylguaiacol that can be generated from those two or more components (for example, a total ingestion concentration) is an amount at which a human can detect a 4-ethylguaiacol odor (for example, an ingestion concentration). "A human can detect a 4-ethylguaiacol odor" may mean, for example, in the case of a retronasal aroma, that a 4-ethylguaiacol odor is detected when the article of the present invention is consumed. "Humans perceive the odor of 4-ethylguaiacol" may mean, for example, in the case of an orthonasal aroma, that the odor of 4-ethylguaiacol is perceived when the article of the present invention is smelled with the nose.
[0073] When the article of the present invention contains a component capable of producing 4-ethylguaiacol, the content of the component capable of producing 4-ethylguaiacol in the article of the present invention (e.g., ingestible concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb (w / w) or more, 500 It may be ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, 50 ppm(w / w) or more, 100 ppm(w / w) or more, 200 ppm(w / w) or more, 500 ppm(w / w) or more, 1000 ppm(w / w) or more, 2000 ppm(w / w) or more, or 5000 ppm(w / w) or more, and may be 10000 ppm(w / w) or less, 5000 ppm(w / w) or less, 2000 ppm(w / w) or less, 1000 ppm(w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 The concentration may be less than or equal to ppm (w / w), less than or equal to 5 ppm (w / w), less than or equal to 2 ppm (w / w), less than or equal to 1 ppm (w / w), less than or equal to 500 ppb (w / w), less than or equal to 200 ppb (w / w), less than or equal to 100 ppb (w / w), less than or equal to 50 ppb (w / w), less than or equal to 20 ppb (w / w), less than or equal to 10 ppb (w / w), less than or equal to 5 ppb (w / w), less than or equal to 2 ppb (w / w), less than or equal to 1 ppb (w / w), less than or equal to 500 ppt (w / w), less than or equal to 200 ppt (w / w), less than or equal to 100 ppt (w / w), less than or equal to 50 ppt (w / w), less than or equal to 20 ppt (w / w), less than or equal to 10 ppt (w / w), less than or equal to 5 ppt (w / w), or less than or equal to 2 ppt (w / w), or any combination thereof that is not inconsistent.The content (e.g., ingestion concentration) of the component capable of generating 4-ethylguaiacol in the article of the present invention is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w) to 5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppm(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 ppm(w / w)~100 ppm(w / w), 100 ppm(w / w)~200 ppm(w / w), 200 ppm(w / w)~500 ppm(w / w), 500 ppm(w / w). ~1000 ppm(w / w), 1000 ppm(w / w)~2000 ppm(w / w), 2000 ppm(w / w)~5000 ppm(w / w), Alternatively, the content may be 5000 ppm (w / w) to 10000 ppm (w / w). The content (e.g., ingestible concentration) of the component capable of producing guaiacol may be, specifically, for example, 1 ppt (w / w) to 10000 ppm (w / w). When an article contains two or more components capable of producing 4-ethylguaiacol, the contents (e.g., ingestible concentration) of the two or more components capable of producing 4-ethylguaiacol in the article may be set independently or in total within the range of the contents (e.g., ingestible concentration) of the components capable of producing 4-ethylguaiacol in the above-exemplified article. Note that, when an article contains two or more components capable of producing 4-ethylguaiacol, "the content of the component capable of producing 4-ethylguaiacol in the article" means the total content of the two or more components capable of producing 4-ethylguaiacol in the article, unless otherwise specified. In addition, when a food contains two or more ingredients that can produce 4-ethylguaiacol, the "concentration of ingredients that can produce 4-ethylguaiacol" means the total concentration of those two or more ingredients in the food that can produce 4-ethylguaiacol, unless otherwise specified.
[0074] When the article of the present invention contains 4-ethylguaiacol, the content of 4-ethylguaiacol in the article of the present invention (e.g., ingested concentration) may be, for example, an amount at which a human senses the odor of 4-ethylguaiacol (e.g., ingested concentration). The amount of 4-ethylguaiacol at which a human senses the odor of 4-ethylguaiacol (e.g., ingested concentration) is as described above.
[0075] When the article of the present invention contains 4-ethylguaiacol, the content of 4-ethylguaiacol in the article of the present invention (e.g., ingestible concentration) is, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more. , 5 ppb(w / w) or more, 10 ppb(w / w) or more, 20 ppb(w / w) or more, 50 ppb(w / w) or more, 100 ppb(w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, 50 ppm(w / w) or more, 100 ppm(w / w) or more, 200 ppm(w / w) or more, 500 ppm(w / w) or more, 1000 ppm(w / w) or more, 2000 ppm(w / w) or more, or 5000 ppm(w / w) or more, and may be 10000 ppm(w / w) or less, 5000 ppm(w / w) or less, 2000 ppm(w / w) or less, 1000 ppm(w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less The content of 4-ethylguaiacol in the article of the present invention (e.g., ingestible concentration) is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), ppt(w / w), 20 ppt(w / w)~50 ppt(w / w), 50 ppt(w / w)~100 ppt(w / w), 100 ppt(w / w)~200 ppt(w / w), 200 ppt(w / w)~500 ppt(w / w), 500 ppt(w / w)~1 ppb(w / w), 1 ppb(w / w)~2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 ppm(w / w)~50 ppm(w / w), 50 ppm(w / w)~100 ppm(w / w), 100 ppm(w / w)~200 ppm(w / w), 200 ppm(w / w)~500 ppm(w / w), 500 ppm(w / w)~1000 ppm(w / w), 1000 ppm(w / w)~2000 The content of 4-ethylguaiacol in the article of the present invention (e.g., ingestible concentration) may be 1000 ppm (w / w), 2000 ppm (w / w) to 5000 ppm (w / w), or 5000 ppm (w / w) to 10000 ppm (w / w). Specifically, for example, it may be 1 ppt (w / w) to 10,000 ppm (w / w).
[0076] When the article of the present invention contains 4-ethylguaiacol and / or components that can produce 4-ethylguaiacol, the total content of 4-ethylguaiacol and / or components that can produce 4-ethylguaiacol in the article of the present invention (e.g., total ingestion concentration) can be, for example, 1 ppt (w / w) or more, 2 ppt (w / w) or more, 5 ppt (w / w) or more, 10 ppt (w / w) or more, 20 ppt (w / w) or more, 50 ppt (w / w) or more, 100 ppt (w / w) or more, 200 ppt (w / w) or more, 500 ppt (w / w) or more, 1 ppb (w / w) or more, 2 ppb (w / w) or more, 5 ppb (w / w) or more, 10 ppb (w / w) or more, 20 ppb (w / w) or more, 50 ppb (w / w) or more, 100 ppb (w / w) or more, 200 ppb(w / w) or more, 500 ppb(w / w) or more, 1 ppm(w / w) or more, 2 ppm(w / w) or more, 5 ppm(w / w) or more, 10 ppm(w / w) or more, 20 ppm(w / w) or more, 50 ppm(w / w) or more, 100 ppm(w / w) or more, 200 ppm(w / w) or more, 500 ppm(w / w) or more, 1000 ppm(w / w) or more, 2000 ppm(w / w) or more, or 5000 ppm(w / w) or more; and may be 10000 ppm(w / w) or less, 5000 ppm(w / w) or less, 2000 ppm(w / w) or less, 1000 ppm(w / w) or less, 500 ppm(w / w) or less, 200 ppm(w / w) or less, 100 ppm(w / w) or less, 50 ppm(w / w) or less, 20 ppm(w / w) or less, 10 ppm(w / w) or less, 5 ppm(w / w) or less, 2 ppm(w / w) or less, 1 ppm(w / w) or less, 500 ppb(w / w) or less, 200 ppb(w / w) or less Lower, 100 ppb(w / w) or less, 50 ppb(w / w) or less, 20 ppb(w / w) or less, 10 ppb(w / w) or less, 5 ppb(w / w) or less, 2 ppb(w / w) or less, 1 ppb(w / w) or less, 500 ppt(w / w) or less, 200 ppt(w / w) or less, 100 ppt(w / w) or less, 50 ppt(w / w) or less, 20 ppt(w / w) or less, 10 ppt(w / w) or less, 5 ppt(w / w) or less, or 2 ppt(w / w) or less, or any non-consistent combination thereof. The total content of 4-ethylguaiacol and / or components capable of producing 4-ethylguaiacol in the article of the present invention (e.g., total ingestion concentration) is specifically, for example, 1 ppt(w / w) to 2 ppt(w / w), 2 ppt(w / w) to 5 ppt(w / w), 5 ppt(w / w) to 10 ppt(w / w), 10 ppt(w / w) to 20 ppt(w / w), 20 ppt(w / w) to 50 ppt(w / w), 50 ppt(w / w) to 100 ppt(w / w), 100 ppt(w / w) to 200 ppt(w / w), 200 ppt(w / w) to 500 ppt(w / w), 500 ppt(w / w) to 1 ppb(w / w), 1 ppb(w / w) to 2 ppb(w / w), 2 ppb(w / w)~5 ppb(w / w), 5 ppb(w / w)~10 ppb(w / w), 10 ppb(w / w)~20 ppb(w / w), 20 ppb(w / w)~50 ppb(w / w), 50 ppb(w / w)~100 ppb(w / w), 100 ppb(w / w)~200 ppb(w / w), 200 ppb(w / w)~500 ppb(w / w), 500 ppb(w / w)~1 ppm(w / w), 1 ppm(w / w)~2 ppm(w / w), 2 ppm(w / w)~5 ppm(w / w), 5 ppm(w / w)~10 ppm(w / w), 10 ppm(w / w)~20 ppm(w / w), 20 It may be ppm(w / w) to 50 ppm(w / w), 50 ppm(w / w) to 100 ppm(w / w), 100 ppm(w / w) to 200 ppm(w / w), 200 ppm(w / w) to 500 ppm(w / w), 500 ppm(w / w) to 1000 ppm(w / w), 1000 ppm(w / w) to 2000 ppm(w / w), 2000 ppm(w / w) to 5000 ppm(w / w), or 5000 ppm(w / w) to 10000 ppm(w / w).The total content (e.g., total consumption concentration) of 4-ethylguaiacol and / or components capable of producing 4-ethylguaiacol in the article of the present invention may specifically be, for example, 1 ppt (w / w) to 10,000 ppm (w / w).
[0077] Also, for example, the active ingredient can be used to suppress the 4-ethylguaiacol odor by contacting it with an article such as waste. That is, the use of the active ingredient (specifically, application of the active ingredient to a target) can include contacting the active ingredient with an article such as waste. That is, the method of the present invention can specifically be, for example, a method for suppressing the 4-ethylguaiacol odor in an article such as waste, including contacting the active ingredient with an article such as waste. The active ingredient can be contacted with an article such as waste as it is, or after being appropriately prepared into a desired form such as a solution. For example, the active ingredient in any form such as a solution can be mixed with an article such as waste, a solution containing the active ingredient can be sprayed onto an article such as waste, or an article such as waste can be immersed in a solution containing the active ingredient.
[0078] Also, for example, the active ingredient can be used to suppress the odor of 4-ethylguaiacol by applying it to a space. That is, the use of the active ingredient (specifically, application of the active ingredient to a target) can be the application of the active ingredient to a space. That is, the method of the present invention can be specifically, for example, a method for suppressing the odor of 4-ethylguaiacol in a space, which includes applying the active ingredient to the space. The active ingredient can be used as it is or after application of an appropriate amount. The active ingredient may be applied to the space by preparing it in a desired form such as a solution. For example, a solution containing the active ingredient may be sprayed into the space.
[0079] When the active ingredient is brought into contact with an article such as waste or when the active ingredient is applied to a space, the concentration of the active ingredient in the solution containing the active ingredient is not particularly limited as long as a masking effect can be obtained. The concentration of the active ingredient in the solution containing the active ingredient may be set, for example, within the range of the content of the active ingredient in the composition of the present invention exemplified above. The concentration of the active ingredient in the solution containing the active ingredient may be set, for example, within the range of the content of the active ingredient in the article exemplified above (for example, the concentration for consumption). The concentration of the active ingredient in the solution containing the active ingredient may be, for example, 1 or more, 2 or more, 5 or more, 10 or more, 20 or more, 50 or more, 100 or more, 200 or more, or 500 or more times the content of the active ingredient in the article exemplified above (for example, the concentration for consumption), and may be 1000 or less, 500 or less, 200 or less, 100 or less, 50 or less, 20 or less, 10 or less, 5 or less, or 2 or less. The concentration of the active ingredient in the solution containing the active ingredient may be, specifically, for example, 1 to 2 times, 2 to 5 times, 5 to 10 times, 10 to 20 times, 20 to 50 times, 50 to 100 times, 100 to 200 times, 200 to 500 times, or 500 to 1000 times the content (for example, ingested concentration) of the active ingredient in the above-exemplified article.
[0080] When the active ingredient is brought into contact with an article such as waste or applied to a space, the amount of the active ingredient used is not particularly limited as long as a masking effect can be obtained. The amount of the active ingredient used may be set, for example, so that the content of the active ingredient in a mixture of the active ingredient and waste falls within the range of the content of the active ingredient in the above-mentioned example article. The amount of the active ingredient used may be, for example, the amount of solution containing the active ingredient (for example, a solution containing the active ingredient at a concentration as exemplified above) used (for example, a spray amount) per 1 kg of an article or per m of space. 3 per unit, 0.1 mL or more, 0.2 mL or more, 0.5 mL or more, 1 mL or more, 2 mL or more, 5 mL or more, 10 mL or more, The amount of the active ingredient may be, for example, the amount of the solution containing the active ingredient (for example, the solution containing the active ingredient at the concentration exemplified above) used (e.g., spray amount) per 1 kg of the article or per m of space, or may be 50 mL or less, 20 mL or less, 10 mL or less, 5 mL or less, 2 mL or less, 1 mL or less, 0.5 mL or less, or 0.2 mL or less, or any combination thereof that is compatible with the above. 3 per mL, 0.1-0.2 mL, 0.2-0.5 mL, 0.5 It may be ~1 mL, 1-2 mL, 2-5 mL, 5-10 mL, 10-20 mL, or 20-50 mL.
[0081] <4> Use of active ingredients The present invention also discloses the use of the active ingredient in the above-mentioned exemplary applications, i.e., for example, the use of the active ingredient for suppressing the odor of 4-ethylguaiacol or for producing an article such as food, and the use of the active ingredient in producing a composition for suppressing the odor of 4-ethylguaiacol or for producing an article such as food.
[0082] The present invention also discloses active ingredients for use in the above-mentioned applications, i.e., active ingredients for use in suppressing the odor of 4-ethylguaiacol or in producing articles such as food, and active ingredients for use in producing a composition for suppressing the odor of 4-ethylguaiacol or in producing articles such as food. EXAMPLES
[0083] The present invention will be described in more detail below with reference to non-limiting examples.
[0084] The raw materials, reagents, compounds, and the like used in the present examples are readily available or can be prepared according to methods commonly practiced in the art, or are commercially available, unless otherwise specified.
[0085] [Test Example 1] Scoring method (swallowing evaluation) (Preparation of evaluation samples) Each compound shown in Table 1 was added to a 5 ppm 4-ethylguaiacol aqueous solution at the concentration shown in Table 1. The concentration of each compound was determined as the maximum concentration (for convenience of explanation, this is referred to as the "threshold concentration") at which the odor of the compound itself was not felt when an aqueous solution containing each compound alone was held in the mouth and swallowed, among the multiple concentrations previously evaluated.
[0086] (Evaluation of the odor masking effect of 4-ethylguaiacol) The odor intensity of 4-ethylguaiacol was evaluated when 5 ml of each evaluation sample was placed in the mouth and swallowed naturally. The odor intensity of 4-ethylguaiacol was scored in the range of 0 to 5 points according to the following evaluation criteria, based on aqueous solutions of 4-ethylguaiacol prepared to 5 ppm, 4 ppm, or 0 ppm. Scoring was carried out by a panel of three experts, and the average score was calculated for each evaluation sample. The results are shown in Table 1.
[0087] [Evaluation Criteria] 0:0ppm 4-ethylguaiacol in aqueous solution (water without 4-ethylguaiacol) odor intensity 3: 4-ethylguaiacol odor intensity of 4ppm 4-ethylguaiacol aqueous solution 5: 4-ethylguaiacol odor intensity of 5ppm 4-ethylguaiacol aqueous solution
[0088] [Masking effect evaluation criteria] - : 4-ethylguaiacol odor intensity is 5.2 or more ± : 4-ethylguaiacol odor intensity is 4.8 or more and less than 5.2 +: 4-ethylguaiacol odor intensity is 4.0 or more and less than 4.8 ++: 4-ethylguaiacol odor intensity is 3 or more and less than 4 +++: 4-ethylguaiacol odor intensity is less than 3 (same intensity as 4 ppm 4-ethylguaiacol)
[0089] The results are shown in Table 1. All of the compounds shown in Table 1 had a 4-ethylguaiacol odor masking effect. The results were positive.
[0090] [Table 1]
[0091] [Test Example 2] 2-AFC method (swallowing evaluation) (Preparation of evaluation samples) Each compound shown in Table 2 was added to a 5 ppm 4-ethylguaiacol aqueous solution at the concentration shown in Table 2. The concentration of each compound was determined as the maximum concentration (for convenience of explanation, this is referred to as the "threshold concentration") at which the odor of the compound itself was not felt when an aqueous solution containing each compound alone was held in the mouth and swallowed, among the multiple concentrations previously evaluated.
[0092] (Evaluation of the odor masking effect of 4-ethylguaiacol) The odor intensity of the 4-ethylguaiacol sample was evaluated against that of the control (5 ppm 4-ethylguaiacol aqueous solution) when 5 ml of the evaluation sample was placed in the mouth and swallowed naturally. The evaluation was carried out by a panel of three experts, and a case in which two or more panelists (66.7% or more) judged the odor to be "weak" was determined to have a masking effect.
[0093] The results are shown in Table 2. All of the compounds shown in Table 2 had a 4-ethylguaiacol odor masking effect. The results were positive.
[0094] [Table 2]
[0095] [Test Example 3] 2-AFC method (smelling evaluation) (Preparation of evaluation samples) Prepare a propylene glycol (PG) solution containing 750 ppm 4-ethylguaiacol A control solution was prepared. A PG solution containing each compound shown in Table 3 at the concentration shown in Table 3 was prepared as a compound solution. A cotton ball containing 10 μl of the control solution was placed in a 110 ml bottle, which was then covered to prepare a control. A cotton ball containing 10 μl of the control solution and 10 μl of the compound solution was placed in a 110 ml bottle, which was then covered to prepare an evaluation sample. After 5 hours or more had passed, the odor was evaluated by sniffing. The concentration of each compound was determined as the maximum concentration (for convenience of explanation, this is referred to as the "threshold") at which the odor of the compound itself was not felt when a cotton ball containing each compound dissolved in a PG solution alone was placed in a 110 ml bottle, which was then covered, and after 5 hours or more had passed, the compound itself was sniffed.
[0096] (Evaluation of the odor masking effect of 4-ethylguaiacol) The lids of each bottle were opened and the odor of the evaluation sample was compared to the control. The strength of the iacol odor was evaluated. The evaluation was carried out by a panel of three experts, with more than two (66. A masking effect was determined to be present if the panel judged the masking effect to be "weak" by at least 7% of the participants.
[0097] The results are shown in Table 3. All of the compounds shown in Table 3 had a 4-ethylguaiacol odor masking effect. The results were positive.
[0098] [Table 3]
Claims
1. 1. A composition for controlling the odor of 4-ethylguaiacol in a subject, comprising: A composition comprising the following component (A): (A)(E)-β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dimethylthiophenol.
2. The composition of claim 1 , wherein the object is an object or a space.
3. The composition of claim 2 , wherein the item is food or waste.
4. A composition for the manufacture of an article, comprising: A composition comprising the following component (A): (A)(E)-β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dimethylthiophenol.
5. The composition of claim 4 , wherein the article is a food product.
6. 6. The composition according to claim 4, wherein the article is an article in which the odor of 4-ethylguaiacol is suppressed.
7. The composition according to any one of claims 2 to 4, wherein the article contains 4-ethylguaiacol and / or a component capable of producing 4-ethylguaiacol.
8. 1. A method for inhibiting the odor of 4-ethylguaiacol in a subject, comprising: A method comprising the step of applying the following component (A) to the subject: (A)(E)-β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol and at least one component selected from the group consisting of benzoyl, β-caryophyllene, and 2,6-dimethylthiophenol.
9. The method of claim 8 , wherein the object is an object or a space.
10. The method of claim 9 , wherein the item is food or waste.
11. The object is an article, The article is a food product, 9. The method of claim 8, wherein said step is adding said component (A) to a raw material of said article.
12. 1. A method of manufacturing an article, comprising the steps of: The method includes the step of adding the following component (A) to a raw material of the article: (A)(E)-β-damascenone, 2,6-dichlorobenzaldehyde, 3,5-dichlorophenol, hinokitiol, propyl gallate, β-naphthyl anthranilate, methyl isothiocyanate, phloretin, apigenin, ethyl mercaptoacetate, allyl isothiocyanate, isobutyl 4-hydroxybenzoate, trans-resveratrol, 4-propylphenol, 1,5-pentanedial, capsaicin, 1-phenyl-1,3-butanedione, 2-methyl-3-furanthiol, (3R / 3S)-3-sulfanylpentan-2-one, 1-pentan-3-one, N-(4-hydroxy-3-methoxybenzyl)nonanamide, 2,5-dimethyl-3-furanthiol, 2-methylbenzenethiol, β-caryophyllene, and at least one component selected from the group consisting of 2,6-dimethylthiophenol.
13. The method of claim 12, wherein the item is a food product.
14. The method according to claim 12 or 13, wherein the article is an article in which the odor of 4-ethylguaiacol is suppressed.
15. The method according to any one of claims 9 to 13, wherein the article or raw material contains 4-ethylguaiacol and / or a component capable of producing 4-ethylguaiacol.
16. The method according to any one of claims 9 to 13, wherein the component (A) is added so that the content in the article is 0.01 ppt (w / w) to 1000 ppm (w / w).
17. The article is a food product, The method according to claim 16, wherein the content is an eating concentration.