External preparation composition for skin

Abstract

To solve the problem that there is a deep relationship between sleep and beauty, and growth hormone secreted from the anterior lobe of the pituitary gland during sleep repairs skin cells and maintains normal turnover; melatonin, which is synthesized and secreted mainly by the pineal gland in humans, is known to play a role as a signal for informing the time of rest at night, to regulate a sleep cycle, and to have antioxidant ability; melatonin decreases with aging and the like, and decrease in the protective effect against skin cell damage leads to skin aging such as wrinkles; in such a background, researches on ingredients that enhance the action of melatonin have been conducted, and external preparations for skin have been developed, but they have not always been satisfactory so far.SOLUTION: The present invention provides a novel composition for external use for skin which promotes expression of genes involved in melatonin synthesis and improves a skin condition by blending a fractionally distilled tea tree oil.SELECTED DRAWING: Figure 1

Description

[Technical field]

[0001] The present invention relates to a skin topical composition containing fractionally distilled tea tree oil. Here, the skin topical composition refers to skin care cosmetics such as face wash, lotion, cream, pack, etc., makeup cosmetics such as foundation, lipstick, mascara, etc., body care cosmetics such as body soap, slimming agent, UV care agent, bath agent, antiperspirant, etc., fragrance cosmetics such as perfume, cologne, etc., including legal cosmetics, quasi-drugs, and medicines. [Background technology]

[0002] There is a deep connection between sleep and beauty. Growth hormone secreted from the anterior pituitary gland during sleep repairs skin cells and maintains normal cell turnover.

[0003] During sleep, we alternate between non-REM and REM sleep, and it is said that growth hormone is secreted during the deep type of non-REM sleep.

[0004] On the other hand, melatonin, which is mainly synthesized and secreted in the pineal gland in humans, is called the sleep hormone and acts as a signal to inform the person when it is time to rest because it is secreted only at night. Melatonin is also known to have antioxidant properties.

[0005] Melatonin is synthesized in the body at night, but this level decreases with age. It is also known that exposure to blue light emitted from smartphones and PCs before sleep suppresses melatonin synthesis, which is one of the causes of insomnia.

[0006] A decrease in melatonin, which also has antioxidant properties, can lead to a weakening of the skin's defense against cell damage, which can lead to skin aging such as wrinkles.

[0007] Topical skin preparations that target melatonin are being researched, as they are expected to not only regulate sleep cycles but also have anti-aging effects. [Prior art documents] [Non-patent literature]

[0008] [Non-Patent Document 1] Atsuhiko Hattori Melatonin and Aging Comparative Physiology and Biochemistry Vol.34 No.1(2017) pp.2-11 DISCLOSURE OF THEINVENTION [Problem to be solved by the invention]

[0009] Against this background, research has been conducted into ingredients that improve sleep cycles and enhance the action of melatonin, which has anti-aging effects through its antioxidant power, and topical skin preparations have been developed, but so far the results have not been entirely satisfactory. [Means for solving the problem]

[0010] The present invention has been made under the above circumstances, and provides a novel skin topical composition that promotes gene expression involved in melatonin synthesis and improves skin condition by incorporating fractionated distilled tea tree oil.

[0011] Claim 1 of the invention is a skin topical composition characterized by containing fractionally distilled tea tree oil.

[0012] Claim 2 of the present invention relates to the composition for external use on the skin according to claim 1, in which the fractionally distilled tea tree oil is 0.01 to 95.0% by mass. Effect of the Invention

[0013] The fractionally distilled tea tree oil of the present invention contains more sesquiterpenes than regular tea tree oil, and this fractionally distilled tea tree oil promotes gene expression related to melatonin synthesis, which improves the sleep cycle and helps maintain healthy skin condition, and also exerts anti-aging effects due to its antioxidant power. [Brief description of the drawings]

[0014] [Figure 1] Figure 1 shows the effect of the fractionally distilled tea tree oil of the present invention in promoting gene expression related to melatonin synthesis. It can be seen that when commercially available fractionally distilled tea tree oil was added at 1%, it promoted gene expression related to melatonin synthesis, including ASMTL, compared to the placebo. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0015] The present invention will now be described in detail. The fractionally distilled tea tree oil used in the present invention is prepared by fractionally distilling tea tree oil to be rich in sesquiterpenes. This is available as a triheptanoin solution under the commercial product "REGENIGHT" from Southern Cross Botanicals, Australia.

[0016] The amount of the fractionally distilled tea tree oil of the present invention is 0.01 to 95.0% by mass, preferably 0.1 to 10.0% by mass, based on the total amount of the skin topical composition using the above-mentioned commercially available raw materials. When preparing a normal skin topical composition, if the amount is less than 0.01% by mass, the anti-aging effect by promoting gene expression related to melatonin synthesis is not exhibited. It is possible to incorporate more than 10.0% by mass up to 95.0% by mass, but this is not preferred because the effect corresponding to the amount incorporated gradually becomes saturated.

[0017] The effect of the skin topical preparation composition of the present invention is to improve the sleep cycle and promote the secretion of growth hormone by promoting the expression of genes involved in melatonin synthesis, and to reduce damage to cells and maintain healthy skin due to the antioxidant power of the synthesized melatonin. Therefore, further effects can be expected by combining the skin topical preparation composition of the present invention with an antioxidant component. Such components include vitamin A and its derivatives, vitamin C and its derivatives, vitamin D and its derivatives, plant extracts, etc.

[0018] In addition to the above essential components, the skin topical preparation composition of the present invention may contain other components that are usually used in skin topical preparation compositions such as cosmetics and pharmaceuticals. Examples of such other components include the following. The skin topical preparation composition of the present invention is produced by blending one or more of these with the above essential components according to a conventional method.

[0019] The oily components include the following: Avocado oil, apricot kernel oil, olive oil, cacao butter, beef tallow, sesame oil, wheat germ oil, camellia oil, safflower oil, hydrogenated moringa oil, soybean oil, tea seed oil, evening primrose oil, camellia oil, glycolipids, triglyceride (C10-18) glyceryl, peppermint leaf oil, palm kernel oil, palm oil, castor oil, sunflower seed oil, boswellia serrata oil, macadamia seed oil, manuka oil, horse fat, melia azadirachta seed oil, cottonseed oil, Japan wax, (moringa oil / hydrogenated moringa oil) esters, coconut oil, lemon fruit oil, phospholipids, horseradish perilla seed oil, etc. Waxes such as carnauba wax, candelilla wax, rice bran wax, hydrogenated jojoba oil, sunflower seed wax, acacia dealbata flower wax, partially hydrogenated jojoba oil, jojoba esters, jojoba seed oil, beeswax, and lanolin. Hydrocarbons such as isoparaffin, hydrogenated polyisobutene, squalane, squalene, ceresin, paraffin, microcrystalline wax, liquid paraffin, and petrolatum. Higher fatty acids such as isostearic acid, oleic acid, stearic acid, palmitic acid, hydroxystearic acid, behenic acid, myristic acid, lauric acid, linoleic acid, and linolenic acid. Higher alcohols such as isostearyl alcohol, 2-octyldodecanol, oleyl alcohol, cholesterol, stearyl alcohol, cetyl alcohol, cetearyl alcohol, soybean sterol, phytosterols, behenyl alcohol, jojoba alcohol, myristyl alcohol, and lanolin alcohol. Alkyl glyceryl ethers such as chimyl alcohol and batyl alcohol. Isostearyl isostearate, phytostearyl isostearate, PG isostearate, cetyl 2-ethylhexanoate, ethoxydiglycol behenate, ethoxydiglycol oleate, hydrolyzed jojoba esters, triethyl citrate, diethylene glycol monoethyl ether, glycol distearate, propylene glycol dinonanoate, cholesteryl stearate, stearyl stearate, tri(caprylic acid / capric acid)glyceryl, tri-2-hexanoate glyceryl, ethylhexyl palmitate, (behenic acid / oleic acid) (behenyl / oleyl) esters, pentaerythritol tetraester, isopropyl jojoba fatty acid, (jojoba oil / macadamia seed oil) esters, ethyl macadamiate, phytosteryl macadamiate, isopropyl myristate, octyldodecyl myristate, butylene glycol coconut oil fatty acid, propylene glycol laurate, diisostearyl malate, and other esters. Silicones such as amino-modified silicone, alkyl-modified silicone, cyclic dimethyl silicone oil, silicone rubber, methylhydrogenpolysiloxane, methylphenylpolysiloxane, and methylpolysiloxane.

[0020] Examples of polyhydric alcohols include ethoxydiglycol, octanediol, glycerin, diethylene glycol, polyglycerins such as diglycerin, dipropylene glycol, 1,3-butylene glycol, propylene glycol, hexanediol, heptanediol, pentanediol, polyethylene glycol, and the like.

[0021] Examples of sugars include xylitol, sucrose, sorbitol, trehalose, lactose, fructose, maltitol, mannitol, rhamnose, and the like.

[0022] Examples of the polymer compound include the following: Natural polymers such as Alcaligenes polysaccharides, alginic acid, casein, curdlan, carrageenan, agar, xanthan gum, chitosan, guar gum, quince seed, collagen, sclerotium gum, gelatin, dextrin, starch, hyaluronic acid, pullulan, pectin, and mannan. Natural polymer derivatives such as acetylated hyaluronic acid, ethyl cellulose, cationic guar gum, cationic cellulose, carboxymethyl cellulose, stearoxy hydroxypropyl methylcellulose, nitrocellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, hydroxypropyl methylcellulose, polyquaternium-10, polyquaternium-67, and methyl cellulose. Synthetic polymers such as POE-POP copolymer, alkyl acrylate copolymer, acrylic acid-acrylic acid amide-ethyl acrylate copolymer, acrylic resin alkanolamine, alkyl acrylate-vinyl acetate copolymer, sodium acrylate copolymer, carboxyvinyl polymer, highly polymerized polyethylene glycol, polymeric silicone, silicone resin, (styrene / acrylates) copolymer, vinyl methyl ether-ethyl maleate copolymer, polyacrylic amide, polysodium acrylate, polydimethylpiperidinium chloride, polyoxypropylene butyl ether, polyvinyl acetate, polyvinyl alcohol, and polyvinylpyrrolidone.

[0023] The surfactants include the following: Anionic surfactants such as acyl N-methyl taurine salts, POE alkyl ether carboxylates, POE alkyl ether sulfates, alkyl ether phosphates, alkylbenzenesulfonates, alkyl sulfates, N-acylamino acid salts, α-olefin sulfonates, higher fatty acid soaps, sodium stearoyl glutamate, and sodium stearoyl lactylate. Cationic surfactants such as alkyltrimethylammonium chloride, dialkyldimethylammonium chloride, and benzalkonium chloride. Amphoteric surfactants such as alkylamidopropyldimethylaminoacetic acid betaine, alkylamido betaine, 2-alkyl-N-carboxymethyl-N-hydroxyethylimidazolinium betaine, alkyldimethylaminoacetic acid betaine, hydrogenated lecithin, lysolecithin, and lecithin. POE alkylamine fatty acid amide, POE alkyl ether, POE POP alkyl ether alkylamine oxide, alkyl glucoside, PEG-6 isostearate, polyglyceryl-6 isostearate, ethoxydiglycol, PEG-8 (caprylic / capric) glyceryls, (candelilla / jojoba / rice bran) polyglyceryl-3 esters, glycerin fatty acid ester, POE glycerin fatty acid ester, polyglyceryl-3 diisostearate, polyglyceryl-3 dioleate, polyglyceryl-6 distearate, fatty acid alkanolamide, PEG fatty acid ester, PEG-40 hydrogenated castor oil, hydrogenated sunflower seed oil glyceryl esters, hydrogenated sunflower seed oil polyglyceryl-3 esters, PEG-6 stearate, PEG-32 stearate, PEG stearate Nonionic surfactants such as -75, glyceryl stearate, polyglyceryl-6 stearate, polyglyceryl-10 stearate, steareth-20, ceteth-20, sorbitan fatty acid esters, POE sorbitan fatty acid esters, POE sorbitol fatty acid esters, triisostearin PEG-6 esters, tribehenin PEG-20 esters, POE castor oil / hydrogenated castor oil, PEG-10 sunflower glycerides, glyceryl behenate, jojoba wax PEG-80 esters, jojoba wax PEG-120 esters, jojoba oil PEG-150 esters, polyoxyethylene beeswax, polyglyceryl-3 beeswax, polysorbate 80, polyglyceryl-6 polyhydroxystearate, polyglyceryl-6 polyricinoleate, PEG-16 macadamia glycerides, and PEG-8 beeswax.

[0024] Examples of coloring materials, powders, and granules include the following. Coloring materials such as inorganic pigments such as yellow iron oxide, carbon black, black iron oxide, red iron oxide, ultramarine, pearl pigments, organic pigments, tar dyes, and natural dyes. Inorganic powders such as zinc oxide, alumina, (alumina / iron oxide / titanium oxide / mica) complex, (alumina / titanium oxide / sodium silicate / silica) complex, (alumina / titanium oxide / silica) complex, (alumina / titanium oxide / silica / dimethicone) complex, (alumina / silica) complex, (alumina / silica / talc) complex, mica, titanium mica, kaolin, magnesium aluminum silicate, titanium oxide, (titanium oxide / zirconium oxide / silica) complex, (titanium oxide / silica) complex, (titanium oxide / talc) complex, iron oxide, (iron oxide / titanium oxide / silica / mica) complex, (iron oxide / titanium oxide / mica) complex, (iron oxide / silica) complex, (iron oxide / silica / dimethicone) complex, silica, (silica / polyurethane-15 / mica) complex, (silica / mica) complex, zeolite, talc, hectorite, bentonite, mica, (mica / polyurethane-15) complex, and sodium magnesium silicate. Organic powders such as silk powder, cellulose powder, nylon powder, and polyethylene powder. Granules of fatty acid esters, cellulose, natural products, nylon, polyethylene, wax, etc.

[0025] Ingredients of natural origin include the following: Elastin, hydrolyzed casein, hydrolyzed keratin, hydrolyzed collagen, hydrolyzed silk, hydrolyzed soy protein, hydrolyzed pearls, chitin, chitosan, collagen, sodium chondroitin sulfate, water-soluble collagen, lactose, sodium hyaluronate, whey protein, peptides, etc. of animal and microbial origin. Acacia Victoria Fruit Extract, Acacia Victoria Seed Extract, Actinidia Deliciosa Fruit Extract, Acronitia Acidula Fruit Extract, Asparagopsis Armata Extract, Acerola Fruit Extract, Anigozanthos Mangresi Flower Extract, Anigozanthos Flavidus Flower / Leaf Extract, Anetrea Anisata Leaf Extract, Alaria Esculenta Extract, Arctium Majus Root Extract, Arnica Flower Extract, Aloe Ferox Leaf Extract, Aloe Barbadensis Leaf Extract, Italian Cypress Leaf / Fruit / Stem Oil, Strawberry Fruit Extract, Ginkgo Biloba Leaf Extract, Iris Root Extract, Witha Nia Somnifera Root Extract, Urtica Dioica Extract, Artemisia Caprifolia Leaf Extract, Ecklonia Radiata Extract, Rubus Fruticosa Fruit Extract, Barley Bark Extract, Thistle Flower / Leaf / Stem Extract, Barley Seed Extract, Panax Ginseng Root Extract, Lamium Extract, Amaranth Flower Extract, Orange Fruit Extract, Orange Fruit Water, Chamomile Flower Extract, Chamomilla Recutita (Matricaria) Extract, Hydrolyzed Wheat Protein, Hydrolyzed Soy Protein, Oat Grain Extract, Guarana Seed Extract, Carrot Extract, Beta-Carotene, Licorice Root Extract, Rubus Idaeus Extract, Rubus Idaeus Fruit Extract Fruit Extract, Kiwi Fruit Extract, Kiwi Fruit Water, Kigelia Africana Fruit Extract, Amberjack Extract, Caviar Lime Extract, Cucumber Fruit Extract, Leptospermum Officinalis Branch / Leaf Extract, Quillaja Quillaja Bark Extract, Guava Fruit Extract, Wolfberry Fruit Extract, Sophora Angustifolia Root Extract, Cranberry Fruit Water, Grevillea Speciosa Flower Extract, Grapefruit Fruit Water, Kunzea Pomifera Fruit Extract, Caper Fruit Extract, Coconut Water, Yeast Extract, Rice Bran Water, Viola Trifolia Extract, Zanthoxylum Piperitum Seed Extract, Santalum Acuminatum Fruit Extract, Lithospermum Root Extract , Syzygium reumanii fruit extract, Citrus glauca fruit extract, Ginger water, Birch extract, Horsetail extract, Japanese cedar bud extract, Scutellaria fruit water, Spirulina platensis extract, Ivy leaf / stem extract, Horse chestnut seed extract, Fraxinus excelsior bark extract, Sambucus nigra flower extract, Achillea millefolium extract, Mentha piperita extract, Sage leaf extract, Mallow flower / leaf / stem extract, Rosa centifolia flower extract, Jasminum officinale flower / leaf extract, Tasmannia lanceolata fruit extract, Tasmannia lanceolata fruit / leaf extract,Davidsonia pruriens fruit extract, Dulse extract, Tea leaf extract, Passiflora incarnata flower extract, Centella asiatica extract, Tea tree leaf extract, Tea tree leaf oil, Terminalia ferdinandiana fruit extract, Angelica acutiloba extract, Calendula officinalis flower extract, Chondrus crispus extract, Solanum tomentosa fruit / leaf / stem extract, Scutellaria baicalensis root extract, Carrot root extract, Garlic root extract, Pineapple fruit extract, Hibiscus flower extract, Bachousia anisata leaf Extract, Backusia citriodora leaf extract, Lotus root water, Lotus flower extract, Papaya fruit extract, Hamamelis virginiana extract, Hamamelis virginiana bark / leaf / branch extract, Chayote fruit extract, Banksia serrata flower extract, Bambusa arundinacea stem, Daisy flower extract, Hinokitiol, Fucus vesiculosus extract, Himantaria elongata extract, Loquat leaf extract, Grape fruit water, Grape leaf extract, Beech tree shoot extract, Plumeria flower extract, Pleioginium thymosum Rense fruit extract, loofah extract, safflower extract, Cucurbita pepo fruit extract, Persian walnut seed extract, henna flower / fruit / leaf extract, Podocarpus elatus fruit extract, Madake extract, Mango fruit extract, Microcitrus australasica fruit extract, Microcitrus austris fruit extract, Mimosa tenuiflora bark extract, Moso bamboo shoot water, Peach leaf extract, Cornflower flower extract, Vegetable oil, Eucalyptus angustifolium flower / leaf / stem extract, Eucalyptus extract, Birch bark extract, Beech bud extract, Ranunculus ficaria extract, Laventula hybrida oil, Labdanum oil, Lavender flower / leaf / stem extract, Apple fruit extract, Apple fruit water, Rumex occidentalis extract, Lemon fruit extract, Lemon fruit water, Lemon myrtle leaf, Rose water, Rosemary leaf extract, Lowbush blueberry fruit extract, Wine extract and other plant-based origins. Mineral origins such as extracts of olivine, malachite, hematite, smithsonite, rhodochrosite, etc.

[0026] Examples of disinfectants and preservatives include the following: Benzoic acid and its salts, benzalkonium chloride, isopropylmethylphenol, chlorhexidine, salicylic acid and its salts, zinc pyrithione, sorbic acid and its salts, dehydroacetic acid and its salts, triclosan, 4-terpineol, trichlorocarbanilide, paraoxybenzoic acid esters (methylparaben, ethylparaben, butylparaben, etc.), piroctone olamine, phenoxyethanol, hexachlorophene, methylisothiazolinone, methylchloroisothiazolinone, etc.

[0027] Antioxidants that may be mentioned include the following: Sodium bisulfite, vitamin C and its derivatives, vitamin E (tocopherols), butyl hydroxyanisole, butyl hydroxytoluene, gallic acid esters, etc. Antioxidant aids such as ascorbic acid, citric acid, cephalin, succinic acid, phytic acid, malonic acid, maleic acid, and phosphoric acid.

[0028] Examples of sequestering agents include: Edetate, citrate, hydroxyethanediphosphonate, phytic acid, malate, and the like.

[0029] Examples of ultraviolet protection agents include the following: Examples of suitable benzoyl perfluoroalkyl esters include urocanic acid, ethylhexyl triazone, octocrylene, ethylhexyl salicylate, diethylamino hydroxybenzoyl hexyl benzoate, para-aminobenzoic acid, octyl para-dimethylaminobenzoate, bis-ethylhexyloxyphenol methoxyphenyl triazine, 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxybenzophenone-5-sulfonic acid, phenylbenzimidazole sulfonic acid, t-butyl methoxydibenzoylmethane, homosalate, polysilicone-15, methylene bisbenzotriazolyl tetramethylbutylphenol, ethylhexyl methoxycinnamate, and 2-methylphenyl 4-methoxycinnamate.

[0030] Examples of pH adjusters include the following: Organic and inorganic alkaline agents such as aminomethylpropanol, aminomethylpropanediol, ammonia water, potassium hydroxide, sodium hydroxide, sodium carbonate, triethanolamine, tromethamine, monoethanolamine, and arginine. Organic and inorganic acids such as citric acid, lactic acid, phosphoric acid, malic acid, and HCl.

[0031] The various physiologically active ingredients include the following: To prevent rough skin, polyhydric alcohols such as glycerin, POE methyl glucoside, and sugars such as trehalose and pullulan. Biopolymers such as elastin, chitin / chitosan, sodium chondroitin sulfate, and sodium hyaluronate. Moisturizing agents such as amino acids, sodium lactate, urea, betaine, and PCA-Na. Lipid components such as cholesterol, sphingolipids, ceramides, and phospholipids. Anti-inflammatory agents such as ε-aminocaproic acid, allantoin, lysozyme chloride, guaiazulene, glycyrrhizic acid derivatives, β-glycyrrhetinic acid, and hydrocortisone. Others include allantoin and antihistamines. Various UV protection agents for the purpose of preventing aging. Antioxidants such as acetylcysteine, oxothiazolidine, ethylbisiminomethylguaiacol manganese chloride, caffeic acid derivatives, carotenoids, glutathione, tannins, vitamins (B2, C, E), hydroxyethylmethylthiopropenamide, flavonoids, ubiquinone, lignans, lycopene, etc. Cell activators such as α-hydroxy acids. Blood flow promoters such as γ-oryzanol, vitamin E and its derivatives. For the purpose of whitening, derivatives of vitamin C, sodium ascorbate, magnesium ascorbyl phosphate, ascorbyl glucoside, etc. Melanin inhibitors such as arbutin, ellagic acid, kojic acid, linoleic acid, linolenic acid, lactic acid, tranexamic acid, etc. Others include aminoethylphosphinic acids, sulfur, glutathione, placenta extract, etc. For the purpose of preventing wrinkles, alpha-hydroxy acids such as citric acid, glycolic acid, tartaric acid, lactic acid, and malic acid, and retinoids (vitamin A derivatives). For hair growth, vasodilators such as capronium chloride and benzyl nicotinate, local stimulants such as capsicum tincture and ginger tincture, female hormones such as estradiol and ethinyl estradiol, and sebum secretion inhibitors such as pyridoxine hydrochloride. Climbazole, zinc pyrithione, piroctone olamine, etc. for the purpose of preventing dandruff and itching. To prevent acne, keratolytic and exfoliating agents such as sulfur, salicylic acid, and resorcinol, and disinfectants such as benzalkonium chloride and halocarban. Antiperspirants such as aluminum chloride, aluminum chlorohydrate, and zinc oxide to prevent underarm odor. For the purpose of various other physiological activities, vitamins such as pantothenic acid, pantethine, vitamin A and its derivatives, nicotinamide, vitamin B2 and its derivatives, vitamin B6 hydrochloride, vitamin B6 dioctanoate, vitamin B6 tripalmitate, vitamin B12, vitamin B15 and its derivatives, vitamin C such as ascorbic acid, ascorbic acid dipalmitate, ascorbic acid phosphate ester (salt), vitamin D, vitamin E such as α-tocopherol, β-tocopherol, γ-tocopherol, vitamin E acetate, vitamin E nicotinate, and vitamin H. Amino acids and their derivatives such as asparagine, aspartic acid, acetyl citrullamide arginine, alanine, arginine, carboxyethyl aminobutyric acid, glycine, glutamyl amidoethyl imidazole, glutamyl amidoethyl indole, glutamine, serine, taurine, tyrosine, decarboxycarnosine HCl, threonine, valine, histidine, hydroxyproline, pyroglutamyl amidoethyl indole, phenylalanine, prolinamidoethyl indole, methylpropylamidoacetyl methionine, leucine, etc. Protein-related substances such as acetyl tetrapeptide-2, acetyl hexapeptide-1, trifluoroacetyl tripeptide-2, tripeptide-1, nanopeptide-1, palmitoyl peptide-1, etc. Silanol derivatives such as ascorbyl methylsilanol pectin, methylsilanol hydroxyproline aspartate, siloxanetriol alginate, silanetriol glutamate, silanediol salicylate, dioleyl tocopheryl methylsilanol, dimethyl oxobenzodioxasilane, silanetriol, silanetriol alginate, silanetriol trehalose ether, dimethylsilanol hyaluronate, polysilicone-3, methylsilanol acetyl tyrosine, methylsilanol sodium lactate, acefylline methylsilanol mannuronate, methylsilanol mannuronate, lysine silanetriol, and copper methylsilanol PCA. Slimming-related ingredients such as caffeine and dulse extract.

[0032] The formulation of the topical skin composition of the present invention may be in the form usually used for topical skin compositions, such as liquid, emulsion, cream, gel, mist, aerosol foam, solid, or powder dispersion.

[0033] In producing the skin topical composition of the present invention, in order to prevent the inactivation of the active ingredients in the fractionally distilled tea tree oil, it is preferable to add the fractionally distilled tea tree oil at the end of the process to reduce heat history. EXAMPLES

[0034] Next, the present invention will be described in more detail with reference to examples. However, the present invention is not limited to these examples. The blending amounts are shown in mass % unless otherwise specified.

[0035] Example 1 Table 1 shows an example of a moisturizing cream formulation. [Table 1]

[0036] Example 2 Table 2 shows an example of the formulation of an oil beauty serum. [Table 2]

[0037] Example 3 Table 3 illustrates the formulation of a moisturizing gel. [Table 3] [Industrial Applicability]

[0038] The present invention can be widely used in the industries of producing and selling external preparation compositions such as cosmetics, quasi-drugs, and pharmaceuticals.

Claims

1. A skin topical composition comprising fractionally distilled tea tree oil.

2. The composition for external use for skin according to claim 1, wherein the fractionally distilled tea tree oil is present in an amount of 0.01 to 95.0% by mass.

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