γ-aminobutyric acid containing composition

Abstract

To induce a flow (zone) state in a subject.SOLUTION: A composition for inducing a flow (zone) state in a subject contains γ-aminobutyric acid (GABA). The composition can induce a flow (zone) state when the subject performs specific work or movement.SELECTED DRAWING: None

Description

[Technical field]

[0001] The present invention relates to a γ-aminobutyric acid (GABA)-containing composition, particularly a flow (zone)-type The present invention relates to a GABA-containing composition for inducing a neurotransmitter-induced neurotransmitter state. [Background technology]

[0002] It is widely distributed in nature and is one of the most widely used amino acids in food that does not impair the taste when added to food. In recent years, gamma-aminobutyric acid (GABA, 4-aminobutyric acid) has been attracting attention. It is an inhibitory neurotransmitter that is found in large amounts in the central nervous system and acts to prevent excess excitatory neurotransmitters. It is known that it suppresses secretion, calms nervous excitement, and exerts a relaxing effect and anti-stress action. It is also known to have effects such as lowering blood pressure, lowering cholesterol, and suppressing the weakening of the immune system. GABA is known to have a wide range of physiological activities. Since it is also found in the body, it is easy to add to food, and GABA is found in many foods, including chocolate and other foods. supplements are sold. Summary of the Invention [Means for solving the problem]

[0003] The present inventors have discovered that GABA can induce a flow (zone) state in a subject. did.

[0004] Therefore, according to a main aspect of the present invention, the following invention is provided. (Item 1) Contains gamma-aminobutyric acid (GABA) and induces a flow (zone) state in subjects A composition for (Item 2) The composition according to the above item, characterized in that it is ingested before carrying out a task. . (Item 3) The flow (zone) state is defined by at least a distortion of perceived time, Item 10. A composition according to any one of the preceding items. (Item 4) The flow (zone) state includes a reduction in the time it takes to feel the flow. Composition of. (Item 5) The composition of any one of the preceding claims, wherein the task includes multitasking. (Item 6) The above items include e-sports, VDT work, digital work, and games. The composition according to any one of the preceding claims. (Item 7) The game is any of the above items, including TV games, PC games, and mobile terminal games. The composition according to any one of claims 1 to 4. (Item 8) Any of the above items taken at least about 2 hours before or immediately before the execution of the task The composition according to any one of claims 1 to 4. (Item 9) Any one of the above items, wherein the content of γ-aminobutyric acid is about 10 to about 1000 mg. The composition according to item 3. (Item 10) The above item, wherein the intake amount of the γ-aminobutyric acid is about 10 to about 1000 mg per day. The composition according to any one of the preceding claims. (Item 11) A composition according to any one of the preceding items, which is taken orally. (Item 12) The above items are beverages, foods, supplements, food additives, quasi-drugs, or medicines The composition according to any one of the preceding claims. (Item 13) The composition according to any one of the preceding items, in the form of a liquid, powder, tablet, or capsule. Composition. (Item 14) A composition according to any one of the preceding items for inducing an exciting feeling. . (Item 15) A composition according to any one of the preceding items for inducing positive feelings. (Item 16) A composition according to any one of the preceding items for reducing loss of vitality and energy. (Item 17) Any of the above items for relieving mental stress and / or fatigue The composition described above. (Item A1) A method for inducing a flow (zone) state in a subject, comprising administering γ-aminobutyric acid ( The method comprises administering to the subject a composition containing GABA. (Item A2) The composition is administered to the subject before the subject performs the task. , The method described in the above item. (Item A3) The flow (zone) state is defined by at least a distortion of perceived time, Item 11. The method according to any one of items 1 to 7. (Item A4) The flow (zone) state includes a reduction in the time it takes to feel the flow. How to. (Item A5) 2. The method of claim 1, wherein the task includes multitasking. (Item A6) The above items include e-sports, VDT work, digital work, and games. 2. The method according to claim 1 . (Item A7) The game is any of the above items, including TV games, PC games, and mobile terminal games. The method according to any one of claims 1 to 5. (Item A8) The composition is administered at least about 2 hours prior to or immediately before the subject performs the task. The method according to any one of the above items, (Item A9) Any one of the above items, wherein the content of γ-aminobutyric acid is about 10 to about 1000 mg. The method according to claim 5. (Item A10) The above item, wherein the dosage of the γ-aminobutyric acid is about 10 to about 1000 mg per day. 2. The method according to claim 1 . (Item A11) The method of any one of the preceding items, wherein the administration is orally. (Item A12) The composition is a beverage, a food, a supplement, a food additive, a quasi-drug, or a medicine. A method according to any one of the above items. (Item A13) Any of the preceding items, wherein the composition is in the form of a liquid, powder, tablet, or capsule. 13. The method according to claim 1. (Item A14) A method according to any one of the preceding items for inducing an exciting feeling. (Item A15) A method according to any one of the preceding items for inducing positive feelings. (Item A16) A method according to any one of the preceding items for reducing loss of vitality and energy. (Item A17) Any of the above items for relieving mental stress and / or fatigue Method of posting. (Item B1) Induce a flow (zone) state in the subject, creating an exciting feeling To induce positive feelings, to reduce loss of vitality and energy, etc. and / or a composition for relieving mental stress and / or fatigue, A composition comprising gamma-aminobutyric acid (GABA). (Item B2) The composition described in the above paragraph for inducing a flow (zone) state in a subject. (Item B3) Any one of the above items to induce an exciting feeling in the subject The composition described. (Item B4) The method according to any one of the preceding items for inducing positive feelings in a subject. composition. (Item B5) A method for reducing a decrease in vitality and energy in a subject, comprising administering to said subject a composition according to any one of the preceding paragraphs. composition. (Item B6) Any of the above items for relieving mental stress and / or fatigue in a subject. The composition according to any one of claims 1 to 4.

[0005] In the present disclosure, one or more of the above features may be used in any combination as specified. It is contemplated that the present disclosure may be provided in combination with any of the following additional embodiments: The advantages will be recognized by those of ordinary skill in the art upon reading and understanding the following detailed description, if necessary.

[0006] In addition, other features and notable actions and effects of the present disclosure besides those described above will be described in the following embodiments of the present invention. This will be clear to those skilled in the art with reference to the accompanying drawings. Effect of the Invention

[0007] According to the present invention, the ingestion of a GABA-containing composition increases flow (zona) in a subject. It is possible to induce a state of mind that requires cognitive and thinking skills, making tasks more efficient. This can be done and is highly useful in everyday life.

[0008] The compositions of the present invention can also induce a flow (zone) state in a subject. This will improve productivity and work efficiency, improve task quality, and reduce stress. Reduce stress and psychological burden, and / or achieve a sense of fulfillment and accomplishment. It becomes. [Brief description of the drawings]

[0009] [Figure 1] FIG. 1 is a schematic diagram showing the timing of the game test, the ingestion of a test beverage, and the VAS questionnaire in one embodiment of the present invention. [Diagram 2] 2 is a graph showing the results of a game test and a VAS questionnaire in one embodiment of the present invention. The game software used was "GHOST SQUADTM" (Sega). [Diagram 3] 3 is a graph showing the results of a game test and a VAS questionnaire in one embodiment of the present invention. The game software used was "TIME CRISIS 4" (Bandai Namco Games). [Figure 4] FIG. 4 is a schematic diagram showing the timing of the game test and the ingestion of the test beverage in one embodiment of the present invention. [Diagram 5] FIG. 5 is a graph showing the results of a game test in one embodiment of the present invention. [Figure 6] 6 shows the results of the distortion of perceived time when taking a placebo, GABA, or caffeine in one embodiment of the present invention. FIG. 6A shows the results when taking GABA, and FIG. 6B shows the results when taking caffeine. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0010] DETAILED DESCRIPTION OF THE DRAWINGS The present disclosure will now be described in detail with reference to the best mode thereof. It should be understood that expressions include the concept of plurals thereof unless otherwise specified. Therefore, singular articles (such as "a," "an," and "the" in English) Unless otherwise specified, it should be understood that the concept of the plural form is also included. Terms used in the specification are defined by their usual meanings in the art unless otherwise specified. Therefore, unless otherwise defined, the terms used in this specification All technical and scientific terms used herein are within the skill of those of ordinary skill in the art to which this disclosure belongs. Therefore, they have the same meaning as commonly understood. In case of conflict, this specification (including definitions) shall govern. ) takes precedence.

[0011] The following provides definitions of terms and / or basic technical content used in this specification. Please explain accordingly.

[0012] As used herein, "about" means ±10% of the preceding numerical value.

[0013] In this specification, the term "flow (zone) state" refers to a state in which brain waves in the mid-awakening range are dominant. For example, this refers to a state in which SMR (Sensory Motor Rhythm) waves are generated as brain waves. In addition to SMR waves (12-15Hz), the brain waves in the mid-awakening region also include high alpha waves (10- 12Hz), low beta waves (15-18Hz), etc., which balance relaxation and concentration. If the peak is the SMR wave with no alpha waves, the person will be more relaxed and less alert, which means high alpha waves. When you feel more focused and alert, you experience low beta waves. When SMR waves occur, you experience flow and zone. It is known that people who have a strong sense of being in a group tend to have a strong sense of being in a group (K. Ueda, Y. Imamura and T. Ibaraki, TechRxiv.Preprint, doi:10.36227 / techrxiv.14787879.v1 (2021).) EEG measurements are performed Any known measurement technique can be used, e.g. fMRI, NIRS, invasive, MEG, EEG The measurement can be performed using various types of electroencephalogram measuring devices such as those described above.

[0014] When you enter a flow state, your concentration increases and you can perform specific actions or tasks with ease. You can be in a state of concentration deeper than your normal state of consciousness. , JeLA Journal Vol.9 / 2009.5 "Flow for Effective e-Learning For the purposes of this specification, the terms flow and zone are synonymous. In addition to measuring brainwaves, whether you are in a flow (zone) state can also be determined by the distortion of perceived time. It is also possible to evaluate the subject's movements without actually performing them when performing a specific action or task. If the time the subject felt was shorter than the time spent working, the subject was in a flow (zone) state. It can be said that this is a state of affairs.

[0015] As used herein, "perceived time distortion" refers to the inconsistency between the experience of time and the actual elapsed time. For example, when a subject performs a specific movement or task, This refers to the case where the subject feels that the task is shorter than the actual task time. The perceived time for working hours is less than about 99%, less than about 98%, less than about 97%, and about 96%. less than, about 95%, less than about 94%, less than about 93%, less than about 92%, less than about 91%, less than about 9 Less than 0%, less than about 89%, less than about 88%, less than about 87%, less than about 86%, less than about 85%, Less than about 84%, Less than about 83%, Less than about 82%, Less than about 81%, Less than about 80%, Less than about 75% less than about 70%, less than about 65%, less than about 60%, less than about 55%, or less than about 50% When this occurs, it can be said that there is a distortion in the sense of time.

[0016] In this specification, "e-sports" is an abbreviation of "electronic sports" and is used In the narrow sense, "eSports" refers to games played using electronic devices. When a competition using a batting or video game is considered a sporting event, This means that e-sports competitions are not only sports games, but also shooting games. games, simulation games, fighting games, racing games, puzzle games, card games Including but not limited to games and RPGs.

[0017] In this specification, "VDT work" refers to visual display (VDT) work using displays, keyboards, etc. This refers to work using digital display terminals (DTVs).

[0018] In this specification, "digital work" refers to any work that is created primarily using a computer or the Internet. Specific examples of digital work include e-mail and chat. Communication using communication tools such as data processing and databases management, website and application development, online marketing, digital This includes content creation.

[0019] (Preferred embodiment) The following describes preferred embodiments of the present disclosure. The embodiments provided below are Provided for better understanding, the scope of the present disclosure should not be limited to the following description. Therefore, those skilled in the art can make appropriate modifications within the scope of the present disclosure in light of the description in this specification. It is apparent that modifications may be made. Also, the following embodiments of the present disclosure may be used alone. may be used or in combination.

[0020] In one aspect of the present invention, a method for the treatment of a subject with γ-aminobutyric acid (GABA)-containing fluroprotein is provided. Compositions for inducing a -zone state are provided.

[0021] γ-Aminobutyric acid (GABA) is an amino acid that is widely distributed in nature, including in vegetables and grains. Therefore, in one embodiment of the present invention, GABA is used as long as it can be used in foods and beverages. The origin is not limited. For example, GABA may be extracted from a plant or purified from the plant. Alternatively, glutamic acid decarboxylase or the like may be added to a raw material containing glutamic acid. It can also be prepared from a fermented product obtained by adding microorganisms such as lactic acid bacteria that contain the enzyme. GABA-containing products and commercially available GABA products may also impair the effects of the composition of the present invention. The composition of the present invention can be used in the range where the above-mentioned components are not affected.

[0022] In one embodiment, the composition of the present invention, when ingested by a subject, induces flow cytometry in the subject. The flow (zone) state in a subject can be induced by the The elephant can be guided to perform a specific action or task, and the specific action or task requires the It may also be a challenge to

[0023] In one embodiment, the task requires at least some concentration in the subject. For example, e-sports, VDT work, digital work, and games (T V games, PC games, and mobile games. It can be a problem-solving process undertaken to achieve a goal, and can occur in environments such as school or work. This does not only include things that are given to you, but also things that you can work on independently. A set of specific tasks or activities designed to facilitate learning, typically aimed at achieving a goal. It can include movement.

[0024] In one embodiment, the task may be single-tasking or multi-tasking. In one embodiment, multitasking refers to performing multiple tasks or operations simultaneously. For example, in the case of VDT work, In this case, the following tasks and actions are examples of single-tasking and multi-tasking: It is possible. <Single task> -Typing games (repeated simple data entry) A shooting PC game where you just shoot targets (just left-click the mouse with one hand. Use the board to switch weapons, change your field of vision, move forward, backward, left and right, jump, and don't crouch. (Games that do not include any movement or bullet reloading operations) <Multitasking> Shooting games While shooting, you can also switch weapons, reload bullets, move forward, backward, left and right, Switching the field of view, checking the map at the same time, etc. Racing games Accelerating, braking, and turning left and right at the same time

[0025] In another embodiment, in the case of a task other than a VDT task, single task and multitask are performed. Examples of multitasks include the following tasks and actions: <Single task> Kraepelin test (simple addition repetition), etc. <Multitasking> Driving a car: steering, turning signals, footwork, looking at other cars, traffic lights, and people Judgment etc. Piano playing: Different movements on the left and right, foot movements, etc.

[0026] eSports is a type of sports that involves playing computer games, video games (PC (Personal Computer) , home game consoles, mobile applications, VR, etc., regardless of the device used. In e-sports, for example, real sports competitions are held. A newly created virtual sports game that uses human play as a game. This includes things that are operated by layers (in the case of a match, the opponent is a computer stain Virtual sports are sports that are actually being played. Virtual sports events based on real sports events or newly created virtual sports events are conducted by computer. It is carried out virtually through simulation, under certain rules and algorithms. This virtual sport is a game in which players and other players in real sports competitions are imitated. A virtual player on the data, or a virtual player on the data generated by a user under certain rules. Virtual players are configured to compete through computer simulation. There are.

[0027] In one embodiment, the game genre of e-sports is not particularly limited, and may be any game genre. For example, fighting games, sports games, shooting games, games, puzzle games, word games, card games, board games, role-playing games e-sports may be an online game or a simulation game. It can be a battle or a team battle. Also, it can be a battle between humans. Or, humans and computers (e.g., AI or robots) may compete against each other. It may also be something.

[0028] VDT work refers to the use of VDTs (Visual Display Terminals) such as displays and keyboards. Digital work refers to work that uses the Internet and other terminals. This refers to work that utilizes computers and the Internet. The problem involves looking at a screen for long periods of time, which can cause eye fatigue and stress. The composition of the present invention induces a flow (zone) state in a subject, thereby improving VD. It can also help reduce fatigue and stress during T-shirt and digital work.

[0029] In one embodiment, the games include TV games, PC games, and mobile games. The game genre is not particularly limited, and can be played using any electronic device. For example, fighting games, sports games, shooting games, racing games, puzzle games , word games, card games, board games, role-playing games or simulation games The composition of the present invention may be a flow ( It can induce a "zone" state, which can improve your score in the game. and efficient progress can be achieved.

[0030] In one embodiment, the composition of the present invention is ingested by a subject prior to performing a task. The composition of the present invention can be administered to a subject in a manner that provides the effects of the composition of the present invention. The drug may be taken at least about 5 hours to about 1 minute before, or immediately before, the task is performed. The upper limit (maximum time) of the timing of the acquisition is, for example, at least about one hour before the subject performs the task. 2 hours before, 3 hours before, 4 hours before, 5 hours before, 6 hours before, or 7:00 The lower limit (minimum time) of the timing of intake is, for example, the time when the subject performs the task. At least about 50 minutes, about 45 minutes, about 40 minutes, about 35 minutes, about 30 minutes, about 2 minutes before administration 5 minutes before, approx. 20 minutes before, approx. 15 minutes before, approx. 10 minutes before, approx. 5 minutes before, approx. 4 minutes before, approx. 3 minutes before, approx. 2 minutes before The timing of intake may be within any of these lower and upper limits. By taking the composition of the present invention before carrying out the task, This allows the subject to be induced into a flow (zone) state when performing the task. In embodiments, the time period in which the composition of the present invention may be taken prior to performing a task may vary. , the type, content, or difficulty of the task, the state or nature of the target, or the flow (zone) of the objective This can be set appropriately depending on the depth of the condition, etc.

[0031] The composition of the present invention induces a flow (zone) state in a subject when ingested by the subject. The term "zone" is typically used in the context of competition or performance. For example, when athletes get into the "zone" during a game, they are You are focused, your actions and your consciousness are fused, the boundaries between yourself and your surroundings are blurred, and you are performing at your best. It means you are in a state where you can perform well. The hands are immune to self-esteem and anxiety and are therefore able to perform at their best. The term "flow" can be used in the context of creative activities and productive work in general, For example, when an artist enters the “flow” state during a creative activity, they are expressing their creative abilities. Flow means being in a state of full potential. By entering flow, artists can: Achieving the highest artistic expression without regard for the attention of others or other outside interference The main difference between Zone and Flow is that Zone is typically focused on competition or performance. Flow is the focus on creative activity or productive work, but neither of these The concept also describes a state of high concentration and self-sufficiency, allowing individuals to perform at their best. Therefore, zone and flow are both states of concentration. It is a psychological concept that explains In this specification, however, they have the same meaning unless otherwise specified.

[0032] The flow state or zone state is a state in which your ability to perform a task improves according to your own capabilities. In other words, the flow state or the zone state is not just a state of high concentration. Unlike the previous condition, they felt that working on the tasks was enjoyable and that their own skills were improving. Even if you have a high level of concentration, it is not always the case that you are in a flow state or in a zone. Whether or not you can do this depends on your personal feelings and experiences, as well as the content and difficulty of the task you are working on. However, they are different.

[0033] Without wishing to be bound by theory, it is believed that ingesting the composition of the present invention reduces vagal afferent nerve activity. It is said that it can affect brain function through the meridians and balance the sympathetic and parasympathetic nervous systems. This will increase the parasympathetic nervous system, which will help you to focus and feel less tense when working on a task. This condition continues and the brain becomes overactive. It is known that the appearance of beta waves can be suppressed by using the composition of the present invention, which adjusts the balance between alpha waves and beta waves, making it possible to create a state in which brain waves in the mid-awakening range, such as SMR waves, are dominant.

[0034] In one embodiment, being in a flow state (zone) is determined by at least the perceived time It can be evaluated by the distortion of the actual body when the subject performs a specific movement or task. If the subject felt that the time was longer or shorter than the duration of the action or task, the subject can be defined as being in a flow state. It refers to a state in which time and the time you feel do not match. For example, when you are tense or happy, When people experience strong emotions, time may seem to pass faster or slower. While not bound to the current theory, this is an argument for the idea that the way people perceive the passage of time is influenced by factors such as attention and thought. This is because people are influenced by factors such as their attention and thoughts. As you process more information during the day, time may seem to pass faster or slower. The composition of the present invention produces such a distortion in perceived time, It is possible to induce a flow (zone) state in a subject, preferably while the subject is performing a specific task. A flow (zone) state can be induced during application.

[0035] In one embodiment, a person is in the flow (zone) state when the perceived time is shortened. The reduction in perceived time means that time feels faster even when the passage of time is the same. It is said.

[0036] In one embodiment of the present invention, the content of GABA in the composition of the present invention is Depending on the method, etc., the concentration or weight may be such that the effect of the composition of the present invention can be obtained. The content of GABA in the composition of the present invention is about 10 to about 100 The lower limit of the content is, for example, about 10 mg or more, about 30 mg or more, about 50mg or more, about 70mg or more, about 100mg or more, about 150mg or more, about 200mg or more above, about 300 mg or more, about 400 mg or more, about 500 mg or more, about 700 mg or more The upper limit of the content is, for example, about 1000 mg or less, about 800 mg or less, about 700 mg or less. g or less, about 600 mg or less, about 500 mg or less, about 400 mg or less, about 300 mg or less, The amount may be less than about 200 mg, less than about 100 mg, or between any of these lower and upper limits. The range of values ​​may be between.

[0037] In one embodiment of the present invention, the composition of the present invention contains, depending on its form, a compound other than GABA. It may contain any additive or ingredient that can be used in an ingestible composition. Examples of these additives and ingredients include vitamins, including vitamin E and vitamin C. , minerals, nutritional ingredients, bioactive ingredients such as fragrances, excipients used in formulation, Mixtures, emulsifiers, tonicity agents (isotonic agents), buffers, solubilizers, preservatives, stabilizers, antioxidants agents, coloring agents, coagulants, or coating agents, etc. isn't it.

[0038] In one embodiment of the present invention, the composition of the present invention is in any form that contains GABA. The form is not particularly limited, and examples thereof include pharmaceutical compositions, foods and beverages (foods for specified health uses, nutritional supplements, etc.) Including functional foods, functional foods such as foods with functional claims, health supplements, health foods, supplements, etc. It may also be a food additive, a quasi-drug, or a medicine.

[0039] In one embodiment of the present invention, the composition of the present invention can be taken orally and is an oral dosage form. When used as a pharmaceutical composition, the form may be, for example, a tablet (including a coated tablet), a capsule, or the like. , powder, granules, powder, liquid, suspension, emulsion, granules, powder, pills, paste , cream, caplet, gel, chewable, stick, etc. In addition, it can be prepared in a form that is easy to mix, such as a powder or granule, and then It can also be used as a raw material for other medicines.

[0040] In one embodiment of the present invention, the compositions of the present invention can be used for non-therapeutic purposes, A non-therapeutic method for inducing a flow (zone) state in a subject by ingestion of a composition according to the present invention. Such methods do not include medical or therapeutic procedures. The subject is not particularly limited, and is preferably a healthy individual. By ingesting the composition shown, the flow (zone) state can be induced. In addition, when used as a medicine or quasi-drug, it has the effect of inducing a flow (zone) state. It can also be used to promote Noh.

[0041] The compositions of the invention can be used in therapeutic applications, and therefore in another aspect of the invention, A method for inducing a flow (zone) state in a subject, comprising administering γ-aminobutyric acid (G In one embodiment, a method is provided comprising administering to the subject a composition containing ABA.

[0042] In one embodiment of the present invention, the amount of GABA contained in the composition of the present invention per day, The amount to be taken per serving depends on the form of the composition, the method of taking, the purpose of use, and the age of the person taking the product. The dosage can be appropriately determined depending on body weight, symptoms, etc. For example, In order to more significantly exert the effect of GABA, the amount of GABA contained in the composition of the present invention is It is preferable to take at least 10 mg per day, and more preferably Preferably, about 25 mg / day or more, about 50 mg / day or more, about 60 mg / day or more, about 80 mg / day or more / day or more, about 100mg / day or more, about 120mg / day or more, about 150mg / day or more, about 1 80mg / day or more, about 200mg / day or more, about 300mg / day or more, about 400mg / day or more Above 500mg / day, 800mg / day, 1000mg / day The amount of GABA contained in the composition of the present invention per day can be taken The limit is the range in which the composition of the present invention can exert a flow (zone) state inducing effect. There are no particular limitations as long as the amount is within this range.

[0043] In one embodiment of the present invention, the frequency of application of the method of the present invention or the intake of the composition of the present invention is The frequency of intake may be one or more times a day within the desired intake range. In addition, the ingestion period also exerts the flow (zone) state-inducing effect of the composition of the present invention. can be set appropriately within the scope possible.

[0044] In one embodiment, the compositions of the present invention are directed to inducing a flow (zone) state in a subject. is provided independently as a means to induce an exciting feeling in the subject. By ingesting the composition of the present invention, it is possible to induce an exciting effect in a subject. This induces a positive feeling, which improves scores and makes students more efficient when working on tasks. Progress can be achieved.

[0045] In another embodiment, the compositions of the present invention induce a flow (zone) state in a subject. It is provided as a means to induce positive feelings in subjects, independently of the By ingesting the composition of the present invention, a positive feeling can be induced in the subject. This will help you improve your score and progress more efficiently when completing tasks. It is possible.

[0046] In another embodiment, the compositions of the present invention induce a flow (zone) state in a subject. Independently of the above, it can be used to alleviate the loss of vitality and energy in a subject. By ingesting the composition of the present invention, the subject is able to reduce the feeling of vitality and energy. This reduces the risk of getting a higher score when completing tasks and allows for more efficient progress. It is possible.

[0047] In another embodiment, the compositions of the present invention induce a flow (zone) state in a subject. and for relieving mental stress and / or fatigue in a subject, independently of By ingesting the composition of the present invention, it is possible to provide a subject with a Reduce mental stress and / or fatigue, which can improve your score when working on a task. It is possible to improve and achieve efficient progress.

[0048] As used herein, "or" means "at least one or more" of the items listed in the sentence. " is used when "or" can be adopted. When a "value" is stated as being "in the range," the range includes the two values ​​themselves. All references cited herein, including scientific articles, patents, patent applications and the like, are incorporated herein by reference in their entirety. are each incorporated by reference herein to the same extent as if specifically set forth herein.

[0049] The present disclosure has been described above by showing preferred embodiments for ease of understanding. The present disclosure will now be described with reference to examples, but the above description and the following examples are for illustrative purposes only. These are provided solely for the purpose of illustration and are not intended to limit the scope of the present disclosure. The present invention is not limited to the embodiments or examples specifically described herein, but is within the scope of the claims. is limited only by EXAMPLES

[0050] (Example 1: Game Test 1) In this example, the change in game score when GABA was taken was confirmed. A total of 10 men and women aged 26-33 (1st test), a total of 19 men and women aged 26-33 (2nd test) The subjects were assessed for their gaming performance after consuming the test beverage. It was a crossover study.

[0051] The test beverages are as follows: ·GABA water (PharmaGABA 200mg / 350mL) · Red Bull® (Arginine 300mg · Caffeine 100mg / 25 0mL) ·Water (250mL)

[0052] In the first test, the game console was Wii (registered trademark) (Nintendo), In the second test, the game was Ghost Squad (Sega), and the game was PlaySt ation(registered trademark)3 (Sony Computer Entertainment), game software :TIME CRISIS 4 (Bandai Namco Games) was used in each case.

[0053] Regarding the VAS survey, the subjects were asked to evaluate their experiences in areas such as "concentration, excitement, and positive thinking." The survey was conducted by taking a questionnaire about the number of people who had autism. The left end of the line in mm is "not felt at all (=0 mm)" and the right end is "the most felt so far (=1 The distance between the left end and the position on the line where the subject arbitrarily marked an X was The difference between the value immediately after taking the test beverage and the value after the test was completed was calculated. The test was evaluated based on the overall experience.

[0054] The timing of the test beverage intake, game play, and VAS questionnaire is shown in Figure 1. That is correct.

[0055] The results of the first test are shown in Figure 2. As can be seen from Figure 2, in the first test, Compared with the group that consumed only 100g of water and the group that consumed an energy drink (Red Bull), The group that took the supplement showed a tendency to improve their game scores and also reduced the number of missed shots. The results of the questionnaire also showed that the group that took GABA were in an excited state during the game, and It is clear that they are feeling more positive.

[0056] The results of the second test are shown in Figure 3. As can be seen from Figure 3, the water was also Compared with the group that consumed GA and the group that consumed an energy drink (Red Bull), The group that took BA showed a tendency to improve their game scores and their accuracy. The group that took GABA also had an increased number of successful missions during the game. According to the results of the study, the group that took GABA were more excited and positive during the game. I can see that they are feeling this way.

[0057] In both the first and second tests, the intake of GABA improved the subjective "ex The "citing" score improved. The "exciting" score improved. At first glance, this seems to contradict the mechanism by which GABA intake stimulates the parasympathetic nervous system, which has already been reported. However, in known reports, the results of simple calculation problems using the Kraepelin test, etc. In subjects who were given a stress test, the intake of GABA was found to be effective in reducing stress and fatigue. On the other hand, in this test, different information is presented every second, and The test involves playing games that require different operations. It is believed that a state of moderate excitement is important when processing information in a rapid manner. In other words, taking GABA improves the balance between the sympathetic and parasympathetic nervous systems. It is believed that the result of this state being created was that the score for "exciting" improved. The results of this study do not contradict existing effects of GABA.

[0058] (Example 2: Game Test 2) In this example, the change in concentration time when GABA was taken was confirmed. At the screening, participants were selected as those who "improved their concentration by playing games" and "had the same effect when ingesting the test food." The seven subjects who met both the above criteria and the following criteria were asked to consume the test beverage. The study was designed as a single-blind crossover study. The test was performed with a wash out period of at least one day.

[0059] The test beverages are as follows: ·Placebo beverage: 0.6% sugar water 250mL ·GABA beverage: 250mL of 0.6% sugar water containing 100mg of GABA

[0060] The game used was a mobile game (Tetris).

[0061] The timing of the test beverage intake and game play is as shown in Figure 4.

[0062] The concentration test was carried out using the JINS MEME ES. From the electrical potential, blinking and eye movement are captured and concentration and zone are calculated.

[0063] The results are shown in Figure 5. As can be seen from Figure 5, taking 100 mg of GABA improved concentration. The total interval rate and the zone rate were significantly increased compared to the placebo group. It was revealed that GABA increases concentration and the Zone.

[0064] Example 3: Evaluation of time interval distortion In this example, we show that the distortion of time intervals, which is characteristic of the flow (zone) state, is induced by GABA intake. We confirmed whether this was caused by

[0065] After taking placebo, GABA, or caffeine, participants typed about 15 minutes later. The game was played for a total of 5 minutes, and time perception was evaluated using a VAS questionnaire. The typing game took about 2 minutes to complete (first half test), and the score was recorded upon completion. The typing game (second half test) started immediately (with an interval of about 10 seconds). After that, participants were asked to fill out a questionnaire asking how the perceived time compared to the actual time (5 minutes). went.

[0066] In addition, we used glasses to measure concentration (JINS MEME) to measure the time spent in a state of concentration or deep concentration. The number of correct inputs (times), average number of inputs (times), and number of mistypes (times) in the typing game were measured. times).

[0067] The results are shown in Figures 6A and 6B. The results show that the concentration time increased compared to the placebo group. In addition, when GABA is taken, the perceived time seems shorter than the actual time. This shows that GABA reduces distortion of perceived time, especially the perceived time It was revealed that a shortening of the

[0068] (Note) As described above, the present disclosure has been illustrated using the preferred embodiments of the present disclosure. It is understood that the scope of the present invention should be interpreted solely by the claims. The patents, patent applications and other documents cited herein are expressly incorporated by reference in their entirety. The contents of which are incorporated herein by reference as if set forth in US Pat. No. 6,393,363. It is understood that. [Industrial Applicability]

[0069] According to the present invention, it is possible to induce a flow (zone) state by taking GABA. This makes it useful in fields that require cognitive and thinking abilities.

Claims

1. Inducing a flow (zone) state in subjects containing gamma-aminobutyric acid (GABA) A composition for

2. The composition according to claim 1, which is to be ingested before carrying out a task. 。

3. The flow (zone) state is defined by at least a distortion of perceived time. Item 2. The composition according to item 1.

4. 10. The composition of claim 1, wherein the flow (zone) state comprises a shortened perceived time.

5. The composition of claim 2 , wherein the task comprises multitasking.

6. 2. The subject matter of claim 1, wherein the subject matter includes e-sports, VDT work, digital work, and games. The composition described in

7. 7. The method according to claim 6, wherein the games include TV games, PC games, and mobile games. Composition of.

8. The method according to claim 2, wherein the drug is taken at least about 2 hours before or immediately before the performance of the task. composition.

9. 2. The composition of claim 1, wherein the gamma-aminobutyric acid content is about 10 to about 1000 mg. thing.

10. 1. The method of claim 1, wherein the intake amount of gamma-aminobutyric acid is about 10 to about 1000 mg per day. The composition described in

11. The composition of claim 1 which is taken orally.

12. 1. The composition according to claim 1, which is a beverage, a food, a supplement, a food additive, a quasi-drug, or a pharmaceutical. The composition described in

13. The composition of claim 1 in the form of a liquid, powder, tablet, or capsule.

14. The composition of claim 1 for inducing an exciting feeling.

15. The composition of claim 1 for inducing positive feelings.

16. The composition according to claim 1 for reducing loss of vitality and energy.

17. The composition according to claim 1 for relieving mental stress and / or fatigue.

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