Interaction contraindications DB with alternative candidate items

Abstract

To provide an interaction contraindications DB with alternative candidate items, which presents an alternative item when there is a database for checking the interaction of medicine but when flagged by a check, and which assists determination of doctors when an alternative item is presented.SOLUTION: Provided is an interaction contraindications DB with alternative candidate items, which assists determination of a doctor looking for an item which is not flagged by a check for interaction from among drugs indicating the same efficacy as a counterpart drug in a combination of drugs flagged by a check. In order to facilitate determining whether or not a relevant item that is found is appropriate as an alternative item for only reasons that the efficacy is same, and to enable a doctor to choose a drug after taking into account, in addition to the efficacy, what action mechanism the drug is working with, the action mechanisms of drugs are preliminarily defined and prepared separately for a given classification, making it possible to present the action mechanism of an alternative item.SELECTED DRAWING: Figure 1

Description

[Technical field]

[0001] The present invention relates to the provision of pharmaceutical information by pharmacists to doctors. [Background technology]

[0002] There may be cases where a combination of drugs prescribed by a doctor to a patient is inappropriate for taking. Pharmacists have a duty to determine whether such combinations exist.

[0003] In such situations, drug interaction checking databases have become a powerful tool to assist pharmacists.

[0004] The structure of the drug interaction check database consists of combinations of two drugs and a rank indicating the degree of interaction. Summary of the Invention [Problem to be solved by the invention]

[0005] If a drug interaction is flagged up in the drug interaction check, one option is to remove that drug combination from the prescription, or to look for alternatives.

[0006] When looking for alternatives, doctors want the replacement medicine to work as similarly as possible.

[0007] Currently, the package insert for each drug is visually examined to see whether substitutes with the same or similar efficacy can be used, and compromises are made where necessary.

[0008] Alternatively, if the combination is contraindicated, the necessary therapeutic advantage is assessed and the drug may be used as is, or if there is no advantage, the decision may be made to remove the drug from the prescription.

[0009] The present invention aims to present alternative drugs to assist doctors in making decisions regarding whether or not to change a prescription as described above.

[0010] To achieve this goal, it is necessary to ensure that the substitute does not trigger any interaction checks and that its efficacy is the same as, or significantly different from, the original drug.

[0011] In this judgment, it is necessary to examine whether the mechanism of action of the drug is the same as that of the original drug, whether it is similar, or different. In some cases, it makes no sense to have the same mechanism of action for the therapeutic purpose, but conversely, in other cases, the purpose can be achieved even if the mechanism is different as long as the same medicinal effect is achieved.

[0012] Therefore, it is important to present the mechanism of action of a drug. The task of reading and checking the information on each package insert is very labor-intensive. [Means for solving the problem]

[0013] The mechanism of action of drugs is described in various ways in drug package inserts. These are divided into certain categories, and a mechanism of action classification is established for each drug.

[0014] A mechanism of action classification will be assigned to the original drugs in the drug interaction contraindication database with potential substitutes, and to alternative drugs. Effect of the Invention

[0015] When alternative products exist, being able to quickly determine the mechanism of action classification can significantly reduce the effort required to determine whether or not to use an alternative product.

[0016] The file format of the drug interaction contraindication database with potential substitute items will be a one-to-one combination of drug interactions to be checked, with an item indicating the pharmacological activity and an item indicating the mechanism of action classification added. [Brief description of the drawings]

[0017] [Figure 1] File format for the database of contraindications for drug interactions with alternative candidates

Claims

1. A database that can suggest alternative drugs to the original drug if a drug combination is flagged during drug interaction checks.

2. This is a database that can display the mechanism of action classification of the original drug and alternative drugs to assist doctors in making decisions.

3. In order to classify the mechanism of action, expressions related to the mechanism of action are extracted from the pharmacological descriptions on the package insert, and the mechanism of action classification uses the expressions on the package insert as is.

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