Kit for demonstration and demonstration method

Abstract

To provide a kit for demonstration and a demonstration method with which demonstration can be safely executed.SOLUTION: Provided is a kit for demonstration for observing, from the difference in color between indicators, the pH of a solution varied by bringing the solution and a dental supply having an acid neutralizing effect and an alkaline neutralizing effect into contact with each other, the kit for demonstration including: a container including one or more indicators (A) selected from a pH indicator (a1) and an oxidation-reduction indicator (a2), a solvent (B), and a solution including (C), alkali (c1) or acid (c2); and a dental supply having an acid neutralizing effect and an alkaline neutralizing effect.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a demonstration kit and a demonstration method.

Background Art

[0002] Tooth decay is caused by acid produced by bacteria demineralizing tooth enamel. Neutralizing this acid can be a preventive measure against tooth decay, that is, it may be possible to maintain healthy teeth. Therefore, the development of such means has been studied, leading to the development of dental products having an acid-neutralizing effect.

[0003] On the other hand, when the oral cavity becomes overly alkaline, it is not preferable because it can cause damage to the oral mucosa. There is also a need for dental products having an effect of neutralizing the oral environment from the alkaline range to near the neutral range (also referred to as the "alkali-neutralizing effect" in the present disclosure).

[0004] These dental products handled in dental clinics have been sold through promotions with demonstrations for dental professionals such as dentists and dental hygienists at exhibitions handling dental hospital pharmaceuticals. Examples of such demonstrations include actually using dental equipment and actually filling and curing composite resin.

Summary of the Invention

Problems to be Solved by the Invention

[0005] In a demonstration regarding a dental product having an acid-neutralizing effect, for example, with respect to a solution containing an indicator, a solvent, and an acid, it is common to add an alkaline dental product that exhibits an acid-neutralizing effect to demonstrate the acid-neutralizing effect. However, when performing this addition operation, there is a possibility that the alkaline dental product may come into contact with the skin of the demonstrator (in the present disclosure, also simply referred to as the "demonstrator") or an observer of the demonstration such as a dental professional (in the present disclosure, also simply referred to as the "observer"). In that case, depending on the concentration and pH of the alkaline dental product, it may invade the skin proteins, reach deep into the skin while penetrating, damage the skin tissue, and cause chemical burns, so its handling must be done carefully.

[0006] Particularly in a demonstration regarding an instrument used at a dental site, while dental professionals are familiar with it, since the demonstration of the present disclosure is a demonstration like a scientific experiment that is not carried out at a dental site, among dental professionals, there are those who are not accustomed to such demonstrations and may accidentally touch the dental products. Also, originally, when the place for the demonstration is limited and too narrow, there may be cases of accidentally touching the dental products. Even if one accidentally touches the dental products, a demonstration kit that is less likely to have an adverse effect on the human body is required.

[0007] The problem to be solved in the present disclosure is to provide a demonstration kit and a demonstration method that can be safely implemented.

Means for Solving the Problem

[0008] As a result of intensive studies, the inventors have found that part or all of the above problems can be solved by a predetermined demonstration kit and a demonstration method.

[0009] The following items are provided by the present disclosure. (Item 1) A demonstration kit for observing the pH of a solution that varies by contacting the solution with a dental product having an acid neutralization effect and an alkali neutralization effect, by the difference in the color of an indicator. A container in which a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) is disposed A dental product having an acid neutralization effect and an alkali neutralization effect A demonstration kit comprising (Item 2) The demonstration kit according to Item 1, further comprising an article having no acid neutralization effect and / or alkali neutralization effect. (Item 3) The demonstration kit according to Item 1 or 2, wherein the indicator (A) is a mixture of methyl red and methylene blue, bromocresol green, bromothymol blue, or phenolphthalein. (Item 4) A demonstration method for observing the pH of a solution that varies by contacting the solution with a dental product having an acid neutralization effect and an alkali neutralization effect, by the difference in the color of an indicator. (1) A step of contacting a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) with a dental product having an acid neutralization effect and an alkali neutralization effect (2) A step of observing the difference in the color of the indicator A demonstration method comprising (Item 5) A demonstration kit for observing the pH of a solution that varies by contacting the solution with a dental product having an acid neutralization effect and an alkali neutralization effect, by the difference in the color of an indicator. A container in which a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) is disposed A dental product having an acid neutralization effect and an alkali neutralization effect Demonstration kit containing (Item 6) A demonstration kit for observing the pH of a solution that varies by contacting the solution with a dental product having an acid neutralizing effect and an alkali neutralizing effect by the difference in the color of an indicator, A container in which a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) is arranged A container in which a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an acid (c2) is arranged Dental products having an acid neutralizing effect and an alkali neutralizing effect Demonstration kit containing

Effect of the Invention

[0010] Since dental products having not only an acid neutralizing effect but also an alkali neutralizing effect exhibit a pH near the neutral range, the demonstrator and the observer can safely conduct and observe the demonstration.

Mode for Carrying Out the Invention

[0011] Throughout the present disclosure, the range of numerical values such as each physical property value and content can be appropriately set (for example, selected from the upper and lower limit values described in each of the following items). Specifically, for the numerical value φ, when A1, A2, A3, etc. are exemplified as the lower limit of the numerical value φ and B1, B2, B3, etc. are exemplified as the upper limit of the numerical value φ, the range of the numerical value φ is A1 or more, A2 or more, A3 or more, B1 or less, B2 or less, B3 or less, A1 to B1, A1 to B2, A1 to B3, A2 to B1, A2 to B2, A2 to B3, A3 to B1, A3 to B2, A3 to B3, etc. are exemplified. In the present disclosure, "~" is used in the sense of including the numerical values described before and after as the lower limit value and the upper limit value. Hereinafter, the demonstration kit provided in the present disclosure, the demonstration method, etc. will be described in detail.

[0012] <A container in which a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) is disposed.> The container of the present disclosure contains a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C). The solution of the present disclosure is either a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1), or a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an acid (c2).

[0013] <Indicator> Examples of the indicator of the present disclosure include at least one indicator selected from a pH indicator (a1) (also referred to as "pH indicator" or "(a1) component" in the present disclosure) and a redox indicator (a2) (also referred to as "redox indicator" or "(a2) component" in the present disclosure). Examples of the indicator of the present disclosure include one selected from a pH indicator, a redox indicator, and a mixture of a pH indicator and a redox indicator.

[0014] <pH indicator> In the present disclosure, various known pH indicators can be used. In the present disclosure, preferably, the following pH indicators can be used under the following conditions. (When the solution is in the acidic range) A pH indicator whose lower limit of the color change range is within the range of pH 0 or more and 7 or less (When the solution is in the alkaline range) A pH indicator whose upper limit of the color change range is within the range of pH 7 or more and 14 or less Note that an indicator whose lower limit of the color change range is pH 0 or more and 7 or less and whose upper limit is pH 7 or more and 14 or less is preferably used both when the pH of the solution is in the acidic range and when it is in the alkaline range.

[0015] As pH indicators, malachite green (color change range (pH): 0.0 - 2.0), methyl violet (color change range (pH): 0.1 - 3.2), brilliant green (color change range (pH): 1.0 - 3.0), metanil yellow (color change range (pH): 1.2 - 2.3), 4 - phenylazodiphenylamine (color change range (pH): 1.2 - 2.6), metacresol purple (color change range (pH): 1.2 - 2.8), thymol blue (color change range (pH): 1.2 - 2.8), 2,6 - dinitrophenol (color change range (pH): 2.4 - 4.0), 2,4 - dinitrophenol (color change range (pH): 2.6 - 4.0), methyl yellow (color change range (pH): 2.9 - 4.0), ethyl orange (color change range (pH): 3.0 - 4.5), bromophenol blue (color change range (pH): 3.0 - 4.6), congo red (color change range (pH): 3.0 - 5.0), methyl orange (color change range (pH): 3.1 - 4.4), naphthyl red hydrochloride (color change range (pH): 3.7 - 5.0), alizarin red S (color change range (pH): 3.7 - 5.2), bromocresol green (color change range (pH): 3.8 - 5.4), 2,5 - dinitrophenol (color change range (pH): 4.0 - 5.8), methyl red (color change range (pH): 4.2 - 6.2), lacmoid (color change range (pH): 4.4 - 6.6), ethyl red (color change range (pH): 4.5 - 6.5), litmus (color change range (pH): 4.5 - 8.3), p - nitrophenol (color change range (pH): 4.8 - 7.6), chlorophenol red (color change range (pH): 5.0 - 6.6), o - nitrophenol (color change range (pH): 5.0 - 7.0), bromocresol purple (color change range (pH): 5.2 - 6.8), bromophenol red (color change range (pH): 5.2 - 7.0), bromothymol blue (color change range (pH): 6.0 - 7.6), neutral red (color change range (pH): 6.8 - 8.0), rosolic acid (color change range (pH): 6.8 - 8.0), phenol red (color change range (pH): 6.8 - 8.4), p - naphtholphthalein (color change range (pH): 7.1 - 8.7), cresol red (color change range (pH): 7.2 - 8.8), thymol blue (color change range (pH): 8.0 - 9.6), phenolphthalein (color change range (pH): 7.8 - 10.0), thymolphthalein (color change range (pH): 8.4 - 10.6) Examples include one or more selected from alizarin yellow R (color change range (pH): 10.1 to 12.0) and 1,3,5-trinitrobenzene (color change range (pH): 12.0 to 14.0).

[0016] Examples of the color at the upper or lower limit of the color change range of the pH indicator include one or more selected from purple, blue-violet, blue, blue-green, green, yellow, orange, red, and colorless.

[0017] Examples of the upper limit (pH) of the color change range of the pH indicator include 14.0, 13.5, 13.0, 12.5, 12.0, 11.5, 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.5, 7.1, 7.0, 6.9, 6.5, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, 2.5, 2.0, 1.5, 1.0, 0.5, etc., and examples of the lower limit (pH) include 13.5, 13.0, 12.5, 12.0, 11.5, 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.5, 7.1, 7.0, 6.9, 6.5, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, 2.5, 2.0, 1.5, 1.0, 0.5, 0.0, etc. In one embodiment, the color change range (pH) of the pH indicator is preferably 0.0 or more and 14.0 or less.

[0018] Examples of the upper limit of the content (in terms of solid content) of the pH indicator when the total amount of the solution is 100% by mass include 0.01, 0.005, 0.001, 0.0005, 0.0001, 0.00005, 0.00001, 0.000005, 0.000001, 0.0000005, 0.0000001% by mass, etc., and examples of the lower limit include 0.005, 0.001, 0.0005, 0.0001, 0.00005, 0.00001, 0.000005, 0.000001, 0.0000005, 0.0000001, 0.00000005% by mass, etc. In one embodiment, the content (in terms of solid content) of the pH indicator when the total amount of the solution is 100% by mass is preferably about 0.00000005 to 0.01% by mass.

[0019] <Redox indicator> As the redox indicator (a2) (also referred to as the "redox indicator" or the "(a2) component" in the present disclosure), examples include one or more selected from phenosaframine, resazurin, tetrazolium salts, methylene blue, variamine blue B, diphenylamine, diphenylbenzidine, diphenylamine sulfonic acid, dimethylferroin, ferroin, and methylferroin.

[0020] Examples of the color of the oxidized form of the redox indicator include one selected from red, blue, reddish purple, purple, yellowish green, and light blue.

[0021] Examples of the color of the reduced form of the redox indicator include red or colorless.

[0022] In the present disclosure, the pH indicator and / or the redox indicator preferably exhibit a color that gives a positive impression when the solution is in the neutral range, that is, when the acid or alkali is neutralized and the state is favorable for teeth and the body. By doing so, it becomes easier for dental professionals to intuitively understand that dental products having an acid-neutralizing effect and an alkali-neutralizing effect can provide a good state for teeth and the body, and it becomes easier to understand the usefulness of dental products having an acid-neutralizing effect and an alkali-neutralizing effect. In the present disclosure, the pH indicator and / or the redox indicator preferably exhibit a color that gives a negative impression when the solution is in the acidic range or the alkaline range, that is, when the state is unfavorable for teeth and the body. By doing so, it becomes easier for dental professionals to intuitively understand that dental products having an acid-neutralizing effect and an alkali-neutralizing effect can change an unfavorable situation for teeth into a good situation, and it becomes easier to understand the usefulness of dental products having an acid-neutralizing effect and an alkali-neutralizing effect. In the present disclosure, the indicator in the case where the solution is in the acidic range is preferably at least one selected from a mixture of methyl red and methylene blue and bromocresol green. In the present disclosure, the indicator in the case where the solution is in the alkaline range is preferably at least one selected from bromothymol blue and phenolphthalein. By using these, it becomes possible to exhibit a color that gives a positive impression in the neutralized state. In the present disclosure, the "acid-neutralizing effect" refers to the effect of raising the relatively low pH of the solution. Preferably, the "acid-neutralizing effect" refers to the effect of changing a pH that is relatively more acidic to more neutral, and more preferably, it refers to the effect of changing a state in the acidic range (pH less than 6.0) to a state in the neutral range (pH 6.0 or more and 8.0 or less). Specific examples of the acid-neutralizing effect include changing a solution with pH 1.0 to pH 7.0 and changing a solution with pH 5.0 to pH 6.5. In the present disclosure, the "alkali-neutralizing effect" refers to the effect of lowering the relatively high pH of the solution. Preferably, the "alkali-neutralizing effect" refers to the effect of changing a pH that is relatively more alkaline to more neutral, and more preferably, it refers to the effect of changing a state in the alkaline range (pH more than 8.0) to a state in the neutral range (pH 6.0 or more and 8.0 or less).As specific examples of the alkali neutralization effect, examples include changing a solution with a pH of 14 to a pH of 7, changing a solution with a pH of 9.0 to a pH of 7.5, and the like.

[0023] When both a pH indicator and a redox indicator are included in the same solution, the colors exhibited by the mixture of the indicators in the neutral range and outside the neutral range are the colors obtained by mixing the colors exhibited by the pH indicator and the redox indicator, respectively, in the neutral range and outside the neutral range. That is, each of the colors of the above solution in the neutral range and outside the neutral range is a mixed color of one color selected from the low pH color and the high pH color exhibited by the pH indicator and one color selected from the color of the oxidized form and the color of the reduced form exhibited by the redox indicator.

[0024] In the present disclosure, the color that gives a negative impression refers to a color having a relatively high numerical value of a* in the chromaticity coordinates of the CIE1976 L*a*b* color space (specifically, a numerical value equal to or higher than the a* value of the color after contact between the solution and a dental product having an acid-neutralizing effect and an alkali-neutralizing effect), preferably a color with a* of -1 or higher. As the color that gives a negative impression in the present disclosure, more preferably, it is a color having a relatively low numerical value of L* in the chromaticity coordinates of the L*a*b* color space (specifically, a numerical value less than the L* value of the color after contact between the solution and a dental product having an acid-neutralizing effect and an alkali-neutralizing effect), and even more preferably, a color with L* less than 72. As the color that gives a negative impression in the present disclosure, particularly preferably, it is a color having a relatively low numerical value of b* in the chromaticity coordinates of the L*a*b* color space (specifically, a numerical value less than the b* value of the color after contact between the solution and a dental product having an acid-neutralizing effect and an alkali-neutralizing effect), and particularly more preferably, a color with b* less than 3. In the present disclosure, the color that gives a positive impression refers to a color having a relatively low numerical value of a* in the chromaticity coordinates of the L*a*b* color space (specifically, a numerical value less than the a* value of the color before contact between the solution and a dental product having an acid-neutralizing effect and an alkali-neutralizing effect), preferably a color with a* less than -1. As the color that gives an even more positive impression in the present disclosure, preferably, it is a color having a relatively high numerical value of L* in the chromaticity coordinates of the L*a*b* color space (specifically, a numerical value equal to or higher than the a* value of the color before contact between the solution and a dental product having an acid-neutralizing effect and an alkali-neutralizing effect), and more preferably, a color with L* of 72 or higher. As the color that gives an even more positive impression in the present disclosure, more preferably, it is a color having a relatively high numerical value of b* in the chromaticity coordinates of the L*a*b* color space (specifically, a numerical value equal to or higher than the b* value of the color before contact between the solution and a dental product having an acid-neutralizing effect and an alkali-neutralizing effect), and more preferably, a color with b* of 3 or higher.

[0025] Examples of the upper limit of L* in the chromaticity coordinates of the L*a*b* color space include 100, 90, 80, 79, 78, 77, 76, 75, 74, 73, 72, 71, 70, 60, 50, 40, 30, 20, 10, etc., and examples of the lower limit include 90, 80, 79, 78, 77, 76, 75, 74, 73, 72, 71, 70, 60, 50, 40, 30, 20, 10, 0, etc. Since the color has a certain degree of lightness and thus gives a bright and positive impression, L* indicating a positive color is preferably a relatively high value, more preferably 72 or more. Since the color has a certain degree of darkness and thus gives a dark and negative impression, L* indicating a negative color is preferably a relatively low value, more preferably less than 72.

[0026] Examples of the upper limit of a* in the chromaticity coordinates of the L*a*b* color space include 60, 50, 40, 30, 20, 10, 5, 4, 3, 2, 1, 0, -1, -2, -3, -4, -5, -10, -20, -30, -40, -50, etc., and examples of the lower limit include 50, 40, 30, 20, 10, 0, -10, -20, -30, -40, -50, -60, etc. Since the color includes those that are associated with negative situations in the medical field, such as red that reminds people of blood and purple that reminds people of internal bleeding, a* indicating a negative color is preferably a relatively high value, more preferably -1 or more. On the other hand, since the color includes green that is associated with no abnormality or problem in the situation, system, etc. and colors that are associated with positive situations, a* indicating a positive color is preferably a relatively low value, more preferably less than -1.

[0027] As upper limits of b* in the chromaticity coordinates of the L*a*b* color space, 60, 50, 40, 30, 20, 10, 5, 4, 3, 2, 1, 0, -1, -2, -3, -4, -5, -10, -20, -30, -40, -50, etc. are exemplified, and as lower limits, 50, 40, 30, 20, 10, 5, 4, 3, 2, 1, 0, -1, -2, -3, -4, -5, -10, -20, -30, -40, -50, -60, etc. are exemplified. Since there are many warm colors and neutral colors, and colors that evoke a warm and positive situation are included, b* indicating a positive color is preferably a relatively high value, more preferably 3 or more. On the other hand, since there are many cool colors and colors that evoke a cold and negative situation are included, b* indicating a negative color is preferably a relatively low value, more preferably less than 3.

[0028] In addition, in the present disclosure, each numerical value of L*a*b* refers to the numerical value in the CIE1976 L*a*b* color space measured under the following conditions. Measuring instrument: Colorimeter (product name "Color measurement for basic tasks color-guide 45 / 0, 4mm" (manufactured by BYK Gardner GmbH)) Standard white plate: (D65 / 10°, L* = 94.98, a* = -1.06, b* = 0.76) Viewing angle: 2° Light source: C

[0029] Also, when it is difficult to distinguish the color difference of the indicator by observation, the color difference of the indicator may be distinguished by measuring the numerical values in the above L*a*b* color space.

[0030] When the total content of the pH indicator and the redox indicator is 100% by mass (in terms of solid content), the upper limit of the content of the pH indicator (in terms of solid content) is exemplified by 90, 85, 80, 75, 70, 65, 60, 55, 50, 45, 40, 35, 30, 25, 20, 15% by mass, etc., and the lower limit is exemplified by 85, 80, 75, 70, 65, 60, 55, 50, 45, 40, 35, 30, 25, 20, 15, 10% by mass, etc. In one embodiment, when the total content of the pH indicator and the redox indicator is 100% by mass (in terms of solid content), the content of the pH indicator (in terms of solid content) is preferably about 10 to 90% by mass, more preferably 40 to 90% by mass, even more preferably 40 to 80% by mass, particularly preferably 40 to 70% by mass, and even particularly preferably 50 to 70% by mass. When the total content of the pH indicator and the redox indicator is 100% by mass (in terms of solid content), the upper limit of the content of the redox indicator (in terms of solid content) is exemplified by 90, 85, 80, 75, 70, 65, 60, 55, 50, 45, 40, 35, 30, 25, 20, 15% by mass, etc., and the lower limit is exemplified by 85, 80, 75, 70, 65, 60, 55, 50, 45, 40, 35, 30, 25, 20, 15, 10% by mass, etc. In one embodiment, when the total content of the pH indicator and the redox indicator is 100% by mass (in terms of solid content), the content of the redox indicator (in terms of solid content) is preferably about 10 to 90% by mass, more preferably 10 to 60% by mass, even more preferably 20 to 60% by mass, particularly preferably 30 to 60% by mass, and even particularly preferably 30 to 50% by mass. By containing methyl red as the pH indicator and methylene blue as the redox indicator within the above preferred ranges, it is possible to particularly clearly show a color with a negative impression in the acidic state and a color with a positive impression in the neutralized state.

[0031] Examples of the upper limit of the content of the redox indicator (in terms of solid content) when the total amount of the solution is 100% by mass include 0.01, 0.005, 0.001, 0.0005, 0.0001, 0.00005, 0.00001, 0.000005, 0.000001, 0.0000005, 0.0000001% by mass, etc. Examples of the lower limit include 0.005, 0.001, 0.0005, 0.0001, 0.00005, 0.00001, 0.000005, 0.000001, 0.0000005, 0.0000001, 0.00000005% by mass, etc. In one embodiment, the content of the redox indicator (in terms of solid content) when the total amount of the solution is 100% by mass is preferably about 0.00000005 to 0.01% by mass.

[0032] <Solvent (B)> Examples of the solvent (B) of the present disclosure (also referred to as "solvent" or "(B) component" in the present disclosure) include water, a water-soluble organic solvent, or a mixture of water and a water-soluble organic solvent, etc.

[0033] The water-soluble organic solvent is not particularly limited as long as it is an organic solvent soluble in water. Examples of the water-soluble organic solvent include one or more selected from alcohols and ethers. Examples of the alcohols include one or more selected from methanol, ethanol, n-propyl alcohol, i-propyl alcohol, n-butyl alcohol, sec-butyl alcohol, t-butyl alcohol, isobutyl alcohol, n-hexyl alcohol, n-octyl alcohol, ethylene glycol, propylene glycol, diethylene glycol, triethylene glycol, and diacetone alcohol. Examples of the ethers include one or more selected from ethylene glycol monobutyl ether, propylene glycol monomethyl ether, and propylene glycol monoethyl ether.

[0034] When using a mixture of water and a water-soluble organic solvent as the solvent, examples of the upper limit of the water content with respect to 100% by mass of the solvent include 100, 99.9, 99, 98, 97, 96, 95, 94, 93, 92, 91, 90, 85, 80, 75, 70, 65, 60, 55% by mass, etc., and examples of the lower limit include 99.9, 99, 98, 97, 96, 95, 94, 93, 92, 91, 90, 85, 80, 75, 70, 65, 60, 55, 50% by mass, etc. In one embodiment, when using a mixture of water and a water-soluble organic solvent as the solvent, the water content with respect to 100% by mass of the solvent is preferably about 50 to 100% by mass, more preferably 80 to 100% by mass.

[0035] When using a mixture of water and a water-soluble organic solvent as the solvent, examples of the upper limit of the content of the water-soluble organic solvent with respect to 100% by mass of the solvent include 50, 45, 40, 35, 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1, 0.1% by mass, etc., and examples of the lower limit include 45, 40, 35, 30, 25, 20, 15, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1, 0.1, 0% by mass, etc. In one embodiment, when using a mixture of water and a water-soluble organic solvent as the solvent, the content of the water-soluble organic solvent with respect to 100% by mass of the solvent is preferably about 0 to 50% by mass, more preferably 0 to 20% by mass.

[0036] Examples of the upper limit of the solvent content when the total amount of the solution is 100% by mass include 99.999999, 99.999995, 99.999990, 99.999500, 99.999000, 99.995000, 99.990000, 99.950000, 99.900000, 99.500000, 99.000000, 95.000000% by mass, etc. Examples of the lower limit include 99.999995, 99.999990, 99.999500, 99.999000, 99.995000, 99.990000, 99.950000, 99.900000, 99.500000, 99.000000, 95.000000, 90.000000% by mass, etc. In one embodiment, the solvent content when the total amount of the solution is 100% by mass is preferably about 90.000000 to 99.999999% by mass, more preferably 99.990000 to 99.999000% by mass.

[0037] <Alkali (c1) or acid (c2) (C)> In order to bring the solution of the present disclosure into a state outside the neutral range, an alkali (c1) (also referred to as "alkali" or "(c1) component" in the present disclosure) or an acid (c2) (also referred to as "acid" or "(c2) component" in the present disclosure) (C) (also referred to as "alkali or acid" or "(C) component" in the present disclosure) may be added.

[0038] Examples of the alkali include one or more selected from ammonia, sodium hydrogen carbonate (baking soda), potassium hydrogen carbonate, sodium hydroxide, potassium hydroxide, calcium hydroxide, sodium carbonate, potassium carbonate, and calcium carbonate.

[0039] Examples of the acid include one or more selected from organic acids and inorganic acids. Examples of the organic acids include one or more selected from acetic acid, citric acid, malic acid, lactic acid, succinic acid, gluconic acid, tartaric acid, glycolic acid, propionic acid, hydroxypropionic acid, malonic acid, butyric acid, hydroxybutyric acid, and fumaric acid. Examples of the inorganic acids include one or more selected from hydrochloric acid, sulfuric acid, carbonic acid, and nitric acid.

[0040] Examples of the upper limit of the acid content (in terms of solid content) when the total amount of the solution is 100% by mass include 0.01, 0.005, 0.001, 0.0005, 0.0001, 0.00005, 0.00001, 0.000005, 0.000001, 0.0000005, 0.0000001% by mass, etc. Examples of the lower limit include 0.005, 0.001, 0.0005, 0.0001, 0.00005, 0.00001, 0.000005, 0.000001, 0.0000005, 0.0000001, 0.00000005% by mass, etc. In one embodiment, the acid content (in terms of solid content) when the total amount of the solution is 100% by mass is preferably about 0.00000005 to 0.01% by mass.

[0041] Examples of the upper limit of the pH of the solution before contacting a dental product having an acid-neutralizing effect and an alkali-neutralizing effect include 14.0, 13.5, 13.0, 12.5, 12.0, 11.5, 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.9, 7.5, 7.0, 6.5, 6.1, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, 2.5, 2.0, 1.5, 1.0, 0.5, etc. Examples of the lower limit include 13.5, 13.0, 12.5, 12.0, 11.5, 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.9, 7.5, 7.0, 6.5, 6.1, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, 2.5, 2.0, 1.5, 1.0, 0.5, 0.0, etc. In one embodiment, the pH of the solution before contacting a dental product having an acid-neutralizing effect and an alkali-neutralizing effect is preferably 0.0 to 14.0, more preferably 0.0 or more and less than 6.0 (acidic range) or more than 8.0 and 14.0 or less (alkaline range), and even more preferably 3.0 or more and less than 6.0 (weakly acidic range) or more than 8.0 and 11.0 or less (weakly alkaline range). When the pH of the solution is in the weakly acidic range to the neutral range or the weakly alkaline range to the neutral range, it is preferable because even if the solution touches the skin of the performer or observer during the demonstration, the possibility of causing harm is low. In the present disclosure, the neutral range refers to a pH of 6.0 or more and 8.0 or less.

[0042] Examples of the upper limit of the pH of the solution after contact with a dental product having an acid-neutralizing effect and an alkali-neutralizing effect include 8.5, 8.0, 7.5, 7.0, 6.5, etc., and examples of the lower limit include 8.0, 7.5, 7.0, 6.5, 6.0, etc. In one embodiment, the pH of the solution after contact with a dental product having an acid-neutralizing effect is preferably 6.0 to 8.5, more preferably 6.0 to 8.0.

[0043] <Container> The container of the present disclosure may have a structure or material that can hold a solution and allow the color of the indicator to be confirmed. The container of the present disclosure may be a self-standing type or a non-self-standing type. Since it is easy for an observer to see and for an implementer to operate, it is preferably a self-standing type. When adopting a non-self-standing type, if there is a structure for supporting the container, it is as preferable as the self-standing type.

[0044] Examples of the raw materials of the container of the present disclosure include AS resin, vinyl chloride, polyethylene, polypropylene, polystyrene, polyester, glass, etc. The raw material of the container of the present disclosure preferably has excellent chemical resistance and transparency to the extent that the color of the indicator can be confirmed. The raw material of the container of the present disclosure is preferably polypropylene. Examples of the types of containers for arranging the solution of the present disclosure include test tubes, tubes, petri dishes, flasks, cylinders, beakers, bottles, tanks, cups, plate trays, plates, balls, tanks, bottles, etc. Since the content of the container of the present disclosure does not spill out, it is preferably a container with a lid, more preferably a tube with a lid.

[0045] Examples of the upper limit of the container capacity (mL) include 50,000, 40,000, 30,000, 20,000, 10,000, 9,000, 8,000, 7,000, 6,000, 5,000, 4,000, 3,000, 2,000, 1,000, 900, 800, 700, 600, 500, 400, 300, 200, 100, 90, 80, 70, 60, 50, 40, 30, 20, 10, 5, etc. Examples of the lower limit include 40,000, 30,000, 20,000, 10,000, 9,000, 8,000, 7,000, 6,000, 5,000, 4,000, 3,000, 2,000, 1,000, 900, 800, 700, 600, 500, 400, 300, 200, 100, 90, 80, 70, 60, 50, 40, 30, 20, 10, 5, 1, etc. In one embodiment, the container capacity (mL) is preferably from 1 to 50,000.

[0046] <Dental supplies> In the present disclosure, "dental supplies" refers to products, intermediates, raw materials, etc. used in the dental industry. Note that "substances having no acid-neutralizing effect and / or no alkali-neutralizing effect" include general products, intermediates, raw materials, etc. not limited to the dental industry. In the present disclosure, the "acid-neutralizing effect" refers to the effect of neutralizing acidity, generally the effect of substances showing alkalinity, and the "alkali-neutralizing effect" refers to the effect of neutralizing alkalinity, generally the effect of substances showing acidity. "Dental supplies having both an acid-neutralizing effect and an alkali-neutralizing effect" are those that can exhibit both the acid-neutralizing effect and the alkali-neutralizing effect. "Substances having no acid-neutralizing effect and / or no alkali-neutralizing effect" may be substances having no acid-neutralizing effect when the solution is acidic, and may be substances having no alkali-neutralizing effect when the solution is alkaline. In any case, they may be substances having neither an acid-neutralizing effect nor an alkali-neutralizing effect.

[0047] Examples of dental supplies include artificial teeth, ceramic materials, impression materials, resin materials, cements, bonding agents, adhesive materials, gypsum and embedding materials, waxes, metal grinding and polishing materials, whitening materials, preventive and hygienic materials, CAD / CAM materials, hard resins, composite resins, and one or more selected from these constituent components. Examples of constituent components include one or more selected from fillers, polymerizable monomers, photoinitiators, chemical initiators, polymerization inhibitors, silane coupling agents, polymerization accelerators, and polymerization inhibitors.

[0048] Examples of the upper limit of the pH when a dental supply having an acid neutralization effect and an alkali neutralization effect is dispersed in water include 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.5, 7.0, 6.5, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, etc. Examples of the lower limit include 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.5, 7.0, 6.5, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, etc. In one embodiment, the pH when a dental supply having an acid neutralization effect and an alkali neutralization effect is dispersed in water is preferably 3.0 to 11.0. The pH when a dental supply having an acid neutralization effect and an alkali neutralization effect is dispersed in water is preferably in the range of weakly acidic (3.0 or more and less than 6.0) to weakly alkaline (more than 8.0 and 11.0 or less), more preferably near the neutral range, so that the implementer and observer can safely perform and observe the demonstration.

[0049] Examples of the upper limit of the pH when a substance having no acid-neutralizing effect and / or alkali-neutralizing effect is dispersed in water include 14.0, 13.5, 13.0, 12.5, 12.0, 11.5, 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.5, 7.0, 6.5, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, 2.5, 2.0, 1.5, 1.0, 0.5, etc. Examples of the lower limit include 13.5, 13.0, 12.5, 12.0, 11.5, 11.0, 10.5, 10.0, 9.5, 9.0, 8.5, 8.0, 7.5, 7.0, 6.5, 6.0, 5.5, 5.0, 4.5, 4.0, 3.5, 3.0, 2.5, 2.0, 1.5, 1.0, 0.5, 0.0, etc. In one embodiment, the pH when a substance having no acid-neutralizing effect and / or alkali-neutralizing effect is dispersed in water is preferably from 0.0 to 14.0. The pH when a substance having no acid-neutralizing effect and / or alkali-neutralizing effect is dispersed in water is preferably in the range of weakly acidic (3.0 or more and less than 6.0) to weakly alkaline (more than 8.0 and 11.0 or less) so that the implementer and observer can safely perform and observe the demonstration.

[0050] Examples of dental products having an acid-neutralizing effect and an alkali-neutralizing effect include ion-releasing glasses having an acid-neutralizing effect and an alkali-neutralizing effect or those containing the same. Examples of the ion-releasing glass include glasses containing one or more glass skeleton-forming elements forming a glass skeleton and one or more glass-modifying elements modifying the glass skeleton.

[0051] Examples of the glass skeleton-forming elements include one or more selected from SiO 2 , Al 2 O 3 , B 2 O 3 , and P 2 O 5 etc.

[0052] As glass modifying elements, examples of one or more selected from halogen elements (for example, one or more selected from fluorine, bromine, iodine, etc.), alkali metal elements (for example, one or more selected from sodium, lithium, etc.), and alkaline earth metal elements (for example, one or more selected from calcium, strontium, etc.) are exemplified. In one embodiment, the glass modifying element is one or more selected from fluorine, sodium, calcium, and strontium.

[0053] As a specific composition of the ion-releasing glass, SiO 2 , Al 2 O 3 , B 2 O 3 , SrO, NaF, CaF 2 , Ca 3 (PO 4 ) 2 , F, SrCO 3 , and one or more selected from Na 2 O are exemplified.

[0054] As the upper limit of the content of SiO 2 with respect to 100% by mass of the ion-releasing glass, 45, 40, 35, 30, 25, 20% by mass, etc. are exemplified, and as the lower limit, 40, 35, 30, 25, 20, 15% by mass, etc. are exemplified. In one embodiment, the content of SiO 2 with respect to 100% by mass of the ion-releasing glass is preferably about 15 to 45% by mass. In the present disclosure, the glass composition can be confirmed by using instrumental analysis such as elemental analysis, Raman spectrum, and fluorescent X-ray analysis. However, there is no problem as long as the actually measured values by any analysis method match these composition ranges.

[0055] As the upper limit of the content of Al 2 O 3 with respect to 100% by mass of the ion-releasing glass, 30, 25, 20, 15% by mass, etc. are exemplified, and as the lower limit, 25, 20, 15, 10% by mass, etc. are exemplified. In one embodiment, the content of Al 2 O 3The content is preferably about 10 to 30% by mass.

[0056] The upper limits of the content of B 2 O 3 with respect to 100% by mass of the ion-releasing glass are exemplified by 20, 15, 10% by mass, etc., and the lower limits are exemplified by 15, 10, 5% by mass, etc. In one embodiment, the content of B 2 O 3 with respect to 100% by mass of the ion-releasing glass is preferably about 5 to 20% by mass.

[0057] The upper limits of the content of P 2 O 5 with respect to 100% by mass of the ion-releasing glass are exemplified by 15, 10, 5, 1% by mass, etc., and the lower limits are exemplified by 10, 5, 1, 0% by mass, etc. In one embodiment, the content of P 2 O 5 with respect to 100% by mass of the ion-releasing glass is preferably about 0 to 15% by mass.

[0058] The upper limits of the content of SrO with respect to 100% by mass of the ion-releasing glass are exemplified by 45, 40, 35, 30, 25% by mass, etc., and the lower limits are exemplified by 40, 35, 30, 25, 20% by mass, etc. In one embodiment, the content of SrO with respect to 100% by mass of the ion-releasing glass is preferably about 20 to 45% by mass.

[0059] The upper limits of the content of F with respect to 100% by mass of the ion-releasing glass are exemplified by 15, 10% by mass, etc., and the lower limits are exemplified by 10, 5% by mass, etc. In one embodiment, the content of F with respect to 100% by mass of the ion-releasing glass is preferably about 5 to 15% by mass.

[0060] The Na 2Examples of the upper limit of the O content include 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 mass%, etc., and examples of the lower limit include 9, 8, 7, 6, 5, 4, 3, 2, 1, 0 mass%, etc. In one embodiment, the content of Na 2 O in 100% by mass of the ion-releasing glass is preferably about 0 to 10% by mass.

[0061] Examples of the upper limit of the NaF content in 100% by mass of the ion-releasing glass include 20, 15, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 mass%, etc., and examples of the lower limit include 15, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1, 0 mass%, etc. In one embodiment, the content of NaF in 100% by mass of the ion-releasing glass is preferably about 0 to 20% by mass.

[0062] Examples of the upper limit of the CaF content in 100% by mass of the ion-releasing glass include 15, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 mass%, etc., and examples of the lower limit include 10, 9, 8, 7, 6, 5, 4, 3, 2, 1, 0 mass%, etc. In one embodiment, the content of CaF in 100% by mass of the ion-releasing glass is preferably about 0 to 15% by mass. 2 Examples of the upper limit of the content of Ca 2 in 100% by mass of the ion-releasing glass include 15, 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 mass%, etc., and examples of the lower limit include 10, 9, 8, 7, 6, 5, 4, 3, 2, 1, 0 mass%, etc. In one embodiment, the content of Ca

[0063] Examples of the upper limit of the content of Ca 3 (PO 4 ) 2 in 100% by mass of the ion-releasing glass include 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 mass%, etc., and examples of the lower limit include 9, 8, 7, 6, 5, 4, 3, 2, 1, 0 mass%, etc. In one embodiment, the content of Ca 3 (PO 4 ) 2 in 100% by mass of the ion-releasing glass is preferably about 0 to 10% by mass.

[0064] Examples of the upper limit of the SrCO content in 100% by mass of the ion-releasing glass include 10, 9, 8, 7, 6, 5, 4, 3, 2, 1 mass%, etc., and examples of the lower limit include 9, 8, 7, 6, 5, 4, 3, 2, 1, 0 mass%, etc. In one embodiment, the content of SrCO in 100% by mass of the ion-releasing glass is preferably about 0 to 10% by mass. 3As the upper limit of the content, 20, 15, 10 mass% etc. are exemplified, and as the lower limit, 15, 10, 5 mass% etc. are exemplified. In one embodiment, for SrCO with respect to 100 mass% of the ion-releasing glass 3 The content is preferably about 5 to 20 mass%.

[0065] As the upper limit of the particle diameter of the ion-releasing glass having an acid-neutralizing effect and an alkali-neutralizing effect, 5, 4, 3, 2, 1, 0.9, 0.8, 0.7, 0.6, 0.5, 0.4, 0.3, 0.2, 0.1, 0.05 μm etc. are exemplified, and as the lower limit, 4, 3, 2, 1, 0.9, 0.8, 0.7, 0.6, 0.5, 0.4, 0.3, 0.2, 0.1, 0.05, 0.01 μm etc. are exemplified. In one embodiment, the particle diameter of the ion-releasing glass having an acid-neutralizing effect and an alkali-neutralizing effect is preferably 0.01 to 5 μm, more preferably 0.5 to 5 μm. When the particle diameter is large, the surface area becomes small, while when the particle diameter is small, it is likely to aggregate, so changes are less likely to appear during the demonstration. In the present disclosure, the particle diameter means the cumulative frequency 50% value of the frequency distribution obtained by a measurement method using a laser diffraction particle size analyzer, that is, the laser diffraction / scattering method (Microtrac method). In the present disclosure, as the laser diffraction particle size analyzer, Microtrac HRAX100 (manufactured by Nikkiso Co., Ltd.) is exemplified.

[0066] Examples of substances having no acid-neutralizing effect and / or alkali-neutralizing effect include substances having no ion-releasing property. Examples of substances having no ion-releasing property include glasses containing one or more glass skeleton-forming elements that form a glass skeleton, and more specifically, silica particles etc. are exemplified.

[0067] <Demonstration> In the present disclosure, "demonstration" refers to showing one or more effects selected from the acid-neutralizing effect and the alkali-neutralizing effect of dental supplies to an observer. The number of observers and the scale of the place are not limited. Also, the demonstration of the present disclosure may be carried out either by the observers themselves or by persons other than the observers.

[0068] <Demonstration Kit> The demonstration kit of the present disclosure includes a container in which a solution containing at least one indicator (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) is arranged It may have a dental product having an acid neutralization effect and an alkali neutralization effect.

[0069] In the present disclosure, an article having no acid neutralization effect and / or alkali neutralization effect may also be included in the demonstration kit. In addition to the dental product having an acid neutralization effect and an alkali neutralization effect, there is an article having no acid neutralization effect and / or alkali neutralization effect, so that they can be observed by comparison in an adjacent state, and it is easy for an observer to understand the acid neutralization effect and the alkali neutralization effect. Also, in the actual demonstration site, the situation of watching the demonstration from the middle is considered, and it is preferable that it is devised so that the understanding can be sufficient even when seen from the middle. By preparing an article having no acid neutralization effect and / or alkali neutralization effect in addition to the dental product having an acid neutralization effect and an alkali neutralization effect, the acidic region state or the alkaline region state can be shown by the article having no acid neutralization effect and / or alkali neutralization effect, and the neutral region state can be shown by the dental product having an acid neutralization effect and an alkali neutralization effect. Therefore, the acid neutralization effect or the alkali neutralization effect can be confirmed at any point in the demonstration.

[0070] In the demonstration kit of the present disclosure, dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect, and items having no acid-neutralizing effect and / or alkali-neutralizing effect can be placed in containers other than the container in which the solution is placed. By putting the contents of the container containing the dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect, and the items having no acid-neutralizing effect and / or alkali-neutralizing effect into the container in which the solution is placed, the two can be brought into contact. Placing dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect, and items having no acid-neutralizing effect and / or alkali-neutralizing effect in a container is preferable because the demonstration can be carried out more safely. When using both dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect and items having no acid-neutralizing effect and / or alkali-neutralizing effect, in order to understand which was placed in a specific container, at least one of the container, the dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect, and the items having no acid-neutralizing effect and / or alkali-neutralizing effect is preferably provided with a display indicating whether it is a dental supply having an acid-neutralizing effect and an alkali-neutralizing effect or an item having no acid-neutralizing effect and / or alkali-neutralizing effect. In addition, when the dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect and the items having no acid-neutralizing effect and / or alkali-neutralizing effect are placed in a container (different from the container in which the solution is placed), the container may be provided with the above display. That is, it is preferably provided with a display indicating either having an acid-neutralizing effect and an alkali-neutralizing effect or having no acid-neutralizing effect and an alkali-neutralizing effect on one or more selected from the solution container, the dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect, the container for the dental supplies having an acid-neutralizing effect and an alkali-neutralizing effect, the items having no acid-neutralizing effect and / or alkali-neutralizing effect, and the container for the items having no acid-neutralizing effect and / or alkali-neutralizing effect.

[0071] <Demonstration method> As a demonstration method of the present disclosure, it may include at least the steps shown in (γ) and (δ) below. That is, (α) and (β) may be prepared before carrying out the demonstration. Step of obtaining a solution by mixing one or more indicators (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C). Step of preparing a dental product having an acid neutralizing effect and an alkali neutralizing effect and / or an article having no acid neutralizing effect and / or no alkali neutralizing effect. Step of bringing the solution of (α) into contact with a dental product having an acid neutralizing effect and an alkali neutralizing effect and / or an article having no acid neutralizing effect and / or no alkali neutralizing effect of (β). Step of observing the difference in the color of the indicator.

[0072] Examples of "preparing a dental product having an acid neutralizing effect and an alkali neutralizing effect and / or an article having no acid neutralizing effect and / or no alkali neutralizing effect" in (β) include the following (β-1) to (β-2). Step of filling a defective part or a cavity part of an artificial tooth with a composite resin having an acid neutralizing effect and an alkali neutralizing effect and / or a composite resin having no acid neutralizing effect and / or no alkali neutralizing effect and curing it for a defective or carious artificial tooth. Step of preparing a predetermined amount of a dental product (such as a filler) having an acid neutralizing effect and an alkali neutralizing effect and / or a dental product (such as a filler) having no acid neutralizing effect and / or no alkali neutralizing effect.

[0073] Examples of the "step of observing the difference in the color of the indicator" in (δ) include the following (δ-1) to (δ-2). Step of observing the difference in the color of the indicator before and after bringing the solution into contact with a dental product having an acid neutralizing effect and an alkali neutralizing effect. Step of observing the difference between the color of the indicator after bringing the solution into contact with a dental product having an acid neutralizing effect and an alkali neutralizing effect and the color of the indicator after bringing the solution into contact with an article having no acid neutralizing effect and / or no alkali neutralizing effect. Note that the color of the indicator before bringing the solution into contact with a dental product having an acid neutralizing effect and an alkali neutralizing effect is preferably a color that gives a negative impression. The color of the indicator after contacting the solution with a dental product having an acid neutralizing effect and an alkali neutralizing effect is preferably a color that gives a positive impression. The color of the indicator after contacting the solution with a substance having no acid neutralizing effect and / or alkali neutralizing effect is preferably a color that gives a negative impression.

[0074] As a demonstration method of the present disclosure, the above (α) to (δ) may be modified and the method may include the steps shown in the following (1) and (2). (1) A step of contacting a solution containing one or more indicators (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) with a dental product having an acid neutralizing effect and an alkali neutralizing effect (2) A step of observing the difference in the color of the indicator

[0075] From the above, as a specific example of the demonstration kit of the present disclosure, 1. A container in which a solution containing one or more indicators (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an alkali (c1) is arranged 2. A container in which a solution containing one or more indicators (A) selected from a pH indicator (a1) and a redox indicator (a2), a solvent (B), and an acid (c2) is arranged 3. A dental product having an acid neutralizing effect and an alkali neutralizing effect or a container in which this is arranged 4. A substance having no acid neutralizing effect and / or alkali neutralizing effect or a container in which this is arranged It is conceivable to prepare. Further, as a specific example of the demonstration method using the demonstration kit, 1. A step of putting the dental product of 3. into the container of 1. 1. A step of putting the substance of 4. into the container of 1. 2. A step of putting the dental product of 3. into the container of 2. 2. A step of putting the substance of 4. into the container of 2. A step of observing the color of each indicator after the above steps is conceivable. In addition, when 3. is a container in which a dental product having an acid-neutralizing effect and an alkali-neutralizing effect is placed, and 4. is a container in which an article having no acid-neutralizing effect and / or alkali-neutralizing effect is placed, the content of 1. or 2. is put into the container of 3. or 4., and it is also conceivable to carry out the demonstration of the present disclosure by observing the color of the indicator.

Example

[0076] Hereinafter, specific examples of the present disclosure will be described with reference to examples, but the present disclosure is not limited to these examples. In the examples, parts and % are all based on mass unless otherwise specified.

[0077] <Production Example 1-1: Production of Solution (1)> At room temperature, 0.002 parts by mass of methyl red as a pH indicator (a1), 0.001 parts by mass of methylene blue as a redox indicator (a2), 249.996 parts by mass of water and 0.996 parts by mass of ethanol as a solvent (B), and 0.004 parts by mass of lactic acid as an acid (c2) were added to a beaker and mixed uniformly. 10 mL of the obtained solution was put into a self-standing sample tube (capacity: 10 mL, material: polypropylene, others: graduated) with a skirt at the conical bottom and tightened with a cap to obtain solution (1). Although the sample tube had a capacity of 10 mL, it actually had a structure with a margin of several mL more in capacity.

[0078] <Production Examples 1-2 to 1-3: Production of Solutions (2) to (3)> Production Examples 1-2 to 1-3 were carried out in the same manner as Production Example 1-1 except that the composition shown in Table 1 was changed to obtain solutions (2) to (3).

[0079] <Performance Evaluation (1): Measurement Test in L*a*b* Color Space> A round mold with an inner diameter of 15 mm and a thickness of 1 mm was placed on the cover glass, and the solution was put inside the mold. A measurement sample was prepared by placing another cover glass on top of the mold. The measurement sample was placed on a standard white plate, and each value in the L*a*b* color space was measured under the following conditions. Measuring instrument: Colorimeter (product name "Color measurement for basic tasks color-guide 45 / 0, 4mm" (manufactured by BYK Gardner GmbH)) Standard white plate: (D65 / 10°, L* = 94.98, a* = -1.06, b* = 0.76) Viewing angle: 2° Light source: C

[0080]

Table 1

[0081] The meanings of the terms in Table 1 are as follows. Methyl red: Product name "Methyl red" (manufactured by Nacalai Tesque, Inc.) Bromocresol green: Product name "Bromocresol green" (manufactured by Fujifilm Wako Pure Chemical Corporation) Methylene blue: Product name "Methylene Blue, Puriss." (manufactured by Waldeck GmbH & Co. KG) Water: Purified water Lactic acid: Product name "Lactic acid" (manufactured by Nacalai Tesque, Inc.)

[0082] <Production Example 2-1: Production of Dental Product (1) Having Acid Neutralization Effect and Alkali Neutralization Effect> To the same sample tube as in Production Example 1-1, 0.1 part by mass of the following polyacrylic acid-treated powder was added.

[0083] SiO 2 at 43% by mass, Al 2 O 3 at 20% by mass, NaF at 5% by mass, CaF 2 at 10% by mass, P 2 O5 5 mass%, SrCO 3 Each raw material was thoroughly mixed at a ratio of 17 mass%, and then charged and retained in a high-temperature electric furnace at 1400 °C to melt the raw materials. After melting, it was cooled to obtain glass. The produced glass was pulverized using a ball mill for 12 hours and passed through a 200-mesh sieve to obtain a glass powder for wet pulverization with an average particle size of about 10 μm. After charging 4 kg of alumina balls with a diameter of 6 mmφ into an alumina pot (internal volume: 3.6 liters) of a four-stage vibration mill, 540 g of the glass powder obtained above and 1 liter of ion-exchanged water were respectively charged, and wet pulverization was carried out for 15 hours. After pulverization, the average particle size and particle size distribution in the pulverized slurry were measured using a laser diffraction particle size analyzer (product name: "Microtrac SPA", manufactured by Microtrac Bell Co., Ltd.). As a result, it showed a monodisperse particle size distribution with an average particle diameter of 3.2 microns. In addition, the alumina balls in the alumina pot after pulverization were separated from the pulverized slurry to obtain a glass inorganic fine particle slurry. 1.5 kg of the glass inorganic fine particle slurry obtained above was charged into a universal mixing and stirring machine, and "MKC Silicate MS51SG1" (SiO 221.7 g of a product with a content of 16% and a degree of polymerization of 2 to 6 (manufactured by Mitsubishi Chemical Corporation) was added and stirred and mixed for about 90 minutes. After mixing for a predetermined time, the obtained treated slurry was aged in a hot air dryer at 50°C for 40 hours, then heated to 150°C and retained for 6 hours, and then cooled to obtain a heat-treated product. The obtained heat-treated product was put into a Henschel mixer and crushed at 1,800 rpm for 5 minutes. After crushing, a "PS-treated filler" with good fluidity and a surface coated with polysiloxane was obtained. As a result of measuring the particle size and particle size distribution of this powder using a laser diffraction particle size analyzer (product name "Microtrac SPA", manufactured by Microtrac Bell Co., Ltd.), the average particle diameter was 3.2 microns and it showed a monodisperse particle size distribution. 2,500 g of the "PS-treated filler" obtained above was put into a Henschel mixer, and while stirring, 575 g of an aqueous polyacrylic acid solution (polymer concentration 13% by mass, weight average molecular weight 20,000; manufactured by Nacalai Tesque, Inc.) was sprayed from above. After spraying, the powder taken out from the Henschel mixer was heated in a hot air dryer at 100°C for 3 hours. After the powder was cooled, 500 g was put into a Henschel mixer and stirred, and while stirring, a solution prepared by dissolving 60 g of 3-(meth)acryloyloxypropylmethoxysilane, which is a silane coupling agent, in 60 g of ethanol was sprayed. After spraying, the powder taken out from the Henschel mixer was heat-treated in a hot air dryer at 100°C for 3 hours to obtain a polyacrylic acid-treated powder, which is an inorganic filler. As a result of measuring the particle size and particle size distribution of this powder using a laser diffraction particle size analyzer (product name "Microtrac SPA", manufactured by Microtrac Bell Co., Ltd.), the average particle diameter was 3.2 microns and it showed a monodisperse particle size distribution.

[0084] <Production Example 3-1: Preparation of a substance (1) having no acid neutralizing effect and / or alkali neutralizing effect> 0.1 part by mass of silica particles (product name "Admafine SO-C3", manufactured by Admatechs Co., Ltd.) was added to the same sample tube as in Production Example 1-1.

[0085] <Example 1> Two solutions (1) were prepared, and a dental product (1) having an acid-neutralizing effect and an alkali-neutralizing effect and an article (1) having no acid-neutralizing effect and / or alkali-neutralizing effect were added to each of them, and the color change was confirmed. The color confirmation method used was the same as that in the performance evaluation (1).

[0086] <Examples 2 to 3> Examples 2 to 3 were carried out in the same manner as Example 1, except that the combination described in Table 2 was changed, and Examples 2 to 3 were implemented.

[0087]

Table 2

[0088] The meanings of the terms in Table 2 are as follows. Solution: The solutions produced in Production Examples 1-1 to 1-3, and (1) to (3) in the table indicate Solutions (1) to (3). Dental product (1): The dental product (1) having an acid-neutralizing effect and an alkali-neutralizing effect prepared in Production Example 2-1, and "〇" in the table indicates that the entire amount was added to the container of the solution. Article (1): The article (1) having no acid-neutralizing effect and / or alkali-neutralizing effect prepared in Production Example 3-1, and "〇" in the table indicates that the entire amount was added to the container of the solution.

[0089] <Example 4> A solution (4) was prepared in the same manner as Production Example 1-1, except that phenolphthalein was used as an indicator and alkali (sodium hydroxide) was used instead of acid. The pH of the solution (4) was 10.5 and the color was pink. When the same dental product (1) as in Examples 1 to 3 was added thereto, the pH of the solution (4) became 7.5 or more and less than 8.0 and the color became colorless. When the article (1) was added, the pH of the solution (4) was 10.5 and the color was pink. The numerical values of colorlessness in the chromaticity coordinates of the L*a*b* color space were L* = 94.98, a* = -1.06, and b* = 0.76.

[0090] <Example 5> Solution (5) was prepared in the same manner as in Production Example 1-1, except that bromothymol blue was used as the indicator and alkali (sodium hydroxide) was used instead of acid. The pH of solution (5) was 10.5 and the color was blue. When the same dental supplies (1) as in Examples 1 to 3 were added thereto, the pH of the solution became 7.5 or more and less than 8.0 and the color became green. When the article (1) was added, the pH of solution (5) was 10.5 and the color was blue.

[0091] <Reference Example 1: Demonstration example using dental supplies (2) having an acid neutralization effect and an alkali neutralization effect obtained by filling and curing a composite resin composition in an artificial tooth having a defect and / or a cavity> (Reference Production Example 1: Production of composite resin composition) 29 parts by mass of UDMA (urethane dimethacrylate) as a polymerizable monomer, 11 parts by mass of TEGDMA (triethylene glycol dimethacrylate), 60 parts by mass of the polyacrylic acid-treated powder of Production Example 2-1 as a filler, 0.21 parts by mass of camphorquinone as a polymerization initiator, and 0.1 part by mass of γ-terpinene and 0.1 part by weight of ethyl dimethylaminobenzoate as a chain transfer agent were put into a container and mixed uniformly to obtain a composite resin composition. (Reference Production Example 2: Production of artificial tooth having a defect and / or a cavity) A columnar cavity with a diameter of 3 mm and a depth of 3 mm was provided on the occlusal surface of the first molar of the artificial tooth with a handpiece. (Reference Example 1) The cavity portion of the artificial tooth of Reference Production Example 2 was filled with the composite resin composition of Reference Production Example 1 and irradiated with light for 20 seconds using a dental light irradiator (product name "Penbright", manufactured by Matsuura Co., Ltd.) to cure the composite resin composition. The resulting product is designated as dental supplies (2). The dental supplies (2) were each put into solutions (3) and (4) of the above Examples one by one, and the change in color of each indicator was confirmed. Solution (3) changes from light blue to pale yellow. Solution (4) changes from pink to colorless.

[0092] The present disclosure is not limited to the above-described embodiments, and can be implemented in various configurations without departing from the gist thereof. Further, the technical features in the embodiments corresponding to the technical features in each aspect described in the summary of the invention can be appropriately replaced or combined in order to solve some or all of the above-described problems, or to achieve some or all of the above-described effects. Further, if the technical feature is not described as essential to the present disclosure, it can be appropriately deleted.

Claims

1. A demonstration kit for observing the pH of a solution that has been changed by contacting the solution with a dental product having an acid-neutralizing effect and an alkali-neutralizing effect, based on the difference in the color of an indicator. a container in which a solution containing one or more indicators (A) selected from a pH indicator (a1) and an oxidation-reduction indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) is placed; Dental products having acid neutralizing and alkali neutralizing effects Demonstration kit including:

2. 2. The demonstration kit of claim 1, wherein the indicator (A) is a mixture of methyl red and methylene blue, bromocresol green, bromothymol blue or phenolphthalein.

3. A demonstration method for observing the pH of a solution that has been changed by contacting the solution with a dental product having an acid-neutralizing effect and an alkali-neutralizing effect, by observing the difference in the color of an indicator. (1) contacting a solution containing one or more indicators (A) selected from a pH indicator (a1) and an oxidation-reduction indicator (a2), a solvent (B), and an alkali (c1) or an acid (c2) (C) with a dental product having an acid-neutralizing effect and an alkali-neutralizing effect; (2) observing the difference in color of the indicator; Demonstration methods including:

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