Intraocular lens having increased optic diameter

Abstract

To improve an intraocular lens whose optic diameter has increased.SOLUTION: Intraocular lens (IOL) designs include a step having an optic with an anterior surface and a posterior surface surrounded by an optic edge. In some examples, the IOL has a plurality of haptics, each attached to the optic at a gusset, where each gusset extends beyond the optic edge toward an optic center so that the gusset at least partially overlaps the anterior surface of the optic. In some examples, the IOL includes a ring structure integral with the optic and surrounding a perimeter of the optic edge, the ring structure having a thickness and the optic edge having a thickness, the ring structure thickness greater than the optic edge thickness.SELECTED DRAWING: Figure 1A

Description

[Technical Field]

[0001] This application claims the benefit of priority to U.S. Provisional Patent Application No. 62 / 949,041, filed December 17, 2019, entitled "Intraocular Lens With Increased Optical Diameter," inventor Mark Andrew Zielke, the entire disclosure of which is fully and completely incorporated herein by reference.

[0002] The present disclosure relates to intraocular lens (IOL) lens design. [Background technology]

[0003] The human eye comprises a cornea and a lens intended to focus light entering the eye's pupil onto the retina. However, the eye can exhibit various refractive errors, which can result in light not being properly focused on the retina and reduced vision. Over the years, numerous therapeutic interventions have been developed to correct various ocular abnormalities (aberrations). These include eyeglasses, contact lenses, corneal refractive surgery such as laser-assisted myopia surgery (LASIK surgery) and corneal implants, and intraocular lenses (IOLs). IOLs are also used to treat cataracts by replacing the patient's eye's natural lens. A typical IOL placement procedure involves inserting an IOL into the patient's capsular bag, replacing the natural lens.

[0004] To insert an IOL into the eye, a foldable intraocular lens is inserted through a temporary open corneal incision, often using a specially designed lens injector. The incision size is usually about 4 mm or less, and the injectable IOL can be about 3 mm or less.

[0005] The most common IOLs have an edge-to-edge optic that is approximately 6.0 mm in diameter. Some patients using 6.0 mm lenses experience visual impairments due to light interacting with the edge of the optic or due to light being deflected from the edge of the optic. While these visual impairments can be reduced with larger diameter lenses, the larger the IOL diameter, the larger the IOL volume, requiring a larger incision. Excessive IOL volume can prevent the IOL from being inserted through a small enough incision in the capsular bag. Summary of the Invention

[0006] In one aspect, the present disclosure is directed to an intraocular lens comprising an optic having an anterior surface and a posterior surface surrounded by an optic edge. The IOL may also have a plurality of haptics, each attached to the optic with a gusset, each gusset extending beyond the optic edge toward the optical center such that the gusset at least partially overlaps the anterior surface of the optic.

[0007] The IOL may have one or more of the following features: (i) The gusset may vary in thickness between its radially innermost edge and the support. (ii) The gusset may increase in thickness as it extends from the radially innermost edge away from the optical center. (iii) The gusset may have a thickness of zero at its radially innermost edge and increase radially to a first thickness at a point beyond the edge of the optic. (iv) The gusset may have a thickness that increases monotonically as it extends outward. (v) The optic may have a maximum thickness that is less than the thickness of the haptics. (vi) The radially innermost edge of the gusset may be at least 2.75 mm from the optical center. (vii) The optic can have a diameter of 6 mm to 8 mm, and the IOL can be 19 mm 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (viii) The optical portion may have a thickness of 0.05 mm to 0.3 mm. (ix) The optical part is 6 mm 3 and the edge of the optical portion may have a diameter of 19 mm. 3 ~23mm 3 The total volume of the sintered body may be 1000 volts. (x) The edge of the optic may have a thickness of 0.25 mm. (xi) 21 diopter IOL is 19 mm 3 The total volume of the sintered body may be 1000 volts. (xii) A 30 diopter IOL is 23 mm 3 The total volume of the sintered body may be 1000 volts. (xiii) The optic may have a diameter of 7 mm and the IOL may have a diameter of 23 mm. 3 ~30mm 3 The total volume of the sintered body may be 1000 volts. (xiv) The edge of the optic may have a thickness of 0.1 mm. (xv) A 21 diopter IOL is 23 mm 3 The total volume of the sintered body may be 1000 volts. (xvi) A 30 diopter IOL is 30 mm 3 The total volume of the sintered body may be 1000 volts. (xvii) The optic may have a diameter of 8 mm and the IOL may have a diameter of 35 mm. 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (xiii) The edge of the optic may have a thickness of 0.1 mm. (xix) 21 diopter IOL is 35mm 3 The total volume of the sintered body may be 1000 volts. (xx) 30 diopter IOL is 48mm 3 The total volume of the sintered body may be 1000 volts. (xxi) The optic and haptics may be made of a soft, foldable optical material. (xxii) The optic, gussets, and haptics may be integrally formed to form a single-piece IOL.

[0008] In another aspect, the IOL comprises an optic having an anterior surface and a posterior surface disposed about an optical axis, the anterior surface and the posterior surface being surrounded by an optic edge connecting the anterior surface and the optic edge defining a periphery of the optic. A gusset connects at least one haptic to at least one of the anterior surface and the posterior surface, the gusset extending radially from an innermost gusset edge to a gusset-haptic junction. The gusset at least partially overlaps at least one of the anterior surface and the posterior surface of the optic.

[0009] The IOL may have one or more of the following additional features: (i) At least one of the front and rear surfaces comprises an optically active area configured to focus light to one or more focal points and a peripheral area surrounding the optically active area, and a radially innermost gusset edge is within the peripheral area. (ii) the anterior and posterior surfaces each comprise an optically active area configured to focus light to one or more focal points, each of the optically active areas extending from the center of the optic to the edge of the optic; (iii) The gusset protrudes from at least one of the anterior and posterior surfaces of the optic. (iv) The gusset protrudes from only one of the anterior and posterior surfaces of the optic such that the cross section of the gusset is asymmetric with respect to a plane perpendicular to the optical axis. (v) The gusset increases in thickness as it extends outward from the innermost gusset edge. (vi) The gusset has a thickness of zero at the gusset edge and increases to a maximum thickness outside the edge of the optic. (vii) The gusset has a thickness that increases monotonically as it extends radially outward. (viii) The maximum thickness of the optical portion is less than the maximum thickness of the haptics. (ix) The radially innermost edge of the gusset is at least 2.75 mm from the optical center. (x) The optic has a diameter of 6 mm to 8 mm, and the IOL is 19 mm 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (xi) The edge of the optical portion has a thickness of 0.05 mm to 0.3 mm. (xii) The optic has a diameter of 6 mm to 8 mm, and the IOL is 19 mm 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (xiii) The edge of the optic has a thickness of 0.25 mm. (xiv) A 21 diopter IOL is 19 mm 3 has a total volume of (xv) A 30 diopter IOL is 23 mm 3 has a total volume of (xvi) The optic has a diameter of 7 mm and the IOL is 23 mm 3 ~30mm 3 has a total volume of (xvii) The edge of the optic has a thickness of 0.1 mm. (xviii) A 21-diopter IOL is 23 mm 3 has a total volume of (xix) A 30 diopter IOL is 23 mm 3 has a total volume of (xx) The optic has a diameter of 8 mm and the IOL is 35 mm 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (xxi) The edge of the optic may have a thickness of 0.1 mm. (xxii) 21 diopter IOL is 35 mm 3 has a total volume of (xxiii) 30 diopter IOL is 48 mm 3 has a total volume of (xxiv) The optic, gussets, and support parts are constructed of a soft, foldable, biocompatible material. (xxv) The optic, gussets, and haptics are integrally constructed to form a single-piece IOL.

[0010] In another aspect, the present disclosure is directed to an IOL having an optic having an optic edge. The IOL can also have a ring structure integral with the optic and surrounding the periphery of the optic edge. Both the ring structure and the optic edge can have a thickness, and the thickness of the ring structure can be greater than the thickness of the optic edge. The IOL can also have a plurality of haptics attached to the ring structure.

[0011] The IOL may have one or more of the following additional features: (i) A step between the edge of the optic and the ring structure. (ii) The steps may be angled, vertical, square, or rounded. (iii) The support and ring structure may be attached at a support-ring junction that may increase in thickness from the ring structure thickness to a point radially beyond the ring structure. (iv) the thickness of the support ring joint may increase monotonically as it extends outward; (v) The maximum thickness of the optic may be less than the thickness of the ring structure. (vi) The optic, ring structure and haptics can be made of a soft, foldable optical material. (vii) The optic can have a diameter of 6 mm to 8 mm, and the IOL can have a diameter of 14 mm. 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (viii) The optic may have a diameter of 6 mm and the IOL may have a diameter of 14 mm. 3 ~18mm 3 The total volume of the sintered body may be 1000 volts. (ix) The optic may have a diameter of 7 mm and the IOL may have a diameter of 23 mm. 3 ~30mm 3 The total volume of the sintered body may be 1000 volts. (x) The optic may have a diameter of 8 mm and the IOL may have a diameter of 35 mm. 3 ~48mm 3 The total volume of the sintered body may be 1000 volts. (xi) The thickness of the edge of the optical zone may be 0.05 mm to 0.3 mm. (xii) The edge thickness of the optical zone may be 0.15 mm. (xiii) The thickness of the ring structure may be 0.2 mm to 0.5 mm. (xiv) The optic may be of a first material and the ring structure and haptics may be of a second material, which may have a higher stiffness than the first material. (xv) the first material can be a soft, foldable optical material; (xvi) The first material can be Acrysof®, p-hydroxyethyl methacrylate, a hydrophobic silicone polymer, an acrylate, or a hydrophilic 2-HEMA homopolymer. (xvii) The second material can be poly(methyl methacrylate), polyvinylidene fluoride (PVDF), polysulfone, or acrylic. (xviii) The ring structure and haptics are molded or bonded to the optic. (xix) The optic can have a diameter of 6 mm to 8 mm, and the IOL can have a diameter of 13 mm. 3 ~46mm 3 The total volume of the sintered body may be 1000 vol. (xx) The optic may have a diameter of 6 mm and the IOL may have a diameter of 13 mm. 3 ~17mm 3 The total volume of the sintered body may be 1000 vol. (xxi) The optic may have a diameter of 7 mm and the IOL may have a diameter of 21 mm. 3 ~28mm 3 The total volume of the sintered body may be 1000 vol. (xxii) The optic may have a diameter of 8 mm and the IOL may have a diameter of 34 mm. 3 ~46mm 3 The total volume of the sintered body may be 1000 vol.

[0012] For a more complete understanding of the present disclosure, reference is now made to the following description taken in conjunction with the accompanying drawings illustrating embodiments of the present disclosure, in which like components have like reference numerals with varying alphabetical designations, such as 10a, 10b, etc. [Brief explanation of the drawings]

[0013] [Figure 1A] FIG. 1A is a top view of the anterior surface of the IOF, with the gussets extending beyond the edge of the optic toward the optical center and partially overlapping the anterior surface of the optic. [Figure 1B] FIG. 1B is a perspective view of the anterior surface of the IOF, with the gussets extending beyond the edge of the optic toward the optical center and overlapping the anterior surface of the optic. [Figure 1C] FIG. 1C is a close-up view of the gussets of the IOF, which extend beyond the edge of the optic toward the optical center and overlap the anterior surface of the optic. [Figure 1D] FIG. 1D is a close-up view of the gussets of the IOF, which extend beyond the edge of the optic toward the optical center and overlap the anterior surface of the optic. [Figure 2A] FIG. 2A is a perspective view of an IOF having a ring structure that wraps around the edge of the optic. [Figure 2B] FIG. 2B is a cross-sectional view of an IOF having a ring structure that surrounds the periphery of the optic edge. [Figure 2C] FIG. 2C is a perspective cross-sectional view of an IOF having a ring structure that surrounds the periphery of the optic edge. [Figure 3A] FIG. 3A is a top view of an IOF having a ring structure around the periphery of the edge of the optic, the optic being a different material than the ring structure and the haptics. [Figure 3B] FIG. 3B is a perspective view of an IOF having a ring structure around the periphery of the edge of the optic, where the optic is a different material than the ring structure and the haptics. [Figure 3C] FIG. 3C is a perspective view of an IOF having a ring structure around the periphery of the edge of the optic, where the optic is a different material than the ring structure and the haptics. DETAILED DESCRIPTION OF THE INVENTION

[0014] The present disclosure relates to an IOL whose diameter can be increased without significantly increasing its overall volume. This can be achieved by using gussets connecting the optic to the haptics. Each gusset originates on the anterior or posterior surface of the optic itself (rather than on the edge of the optic) and extends radially outward toward the haptics, thus partially overlapping the anterior (or posterior) surface of the optic. The gussets can be positioned outside the optically active region of the optic (e.g., beyond 2.5 mm to 3 mm from the optical center) to minimize potential adverse effects on the patient's vision. Alternatively, the entire posterior and / or anterior surface of the optic can be optically active. (The optically active region of an IOL can have one or more surface profiles on the anterior and / or posterior surface of the optic that are collectively configured to focus light to one or more focal points to provide the patient's vision correction.) By coupling the haptics with gussets connected on the anterior or posterior surface of the optic, the edges of the optic are not required to structurally support the haptics. Thus, the optic can be made relatively thin, reducing the overall volume, even with a relatively large optic (eg, having a diameter greater than 6 mm).

[0015] Such benefits may alternatively, or where appropriate, additionally, be achieved by using a ring structure around the periphery of the edge of the optical portion, which may be made of the same material as the optical portion or may be made of a second material having a higher stiffness than the first material from which the optical portion is made.

[0016] In FIGS. 1A-1D, the anterior surface of IOL 100 is shown to have an optic 110 and two haptics 120 attached to optic 110 by gussets 130 .

[0017] The optic 110 has an anterior surface and a posterior surface (not shown) connected and surrounded by the optic edge 140. By reducing the thickness of the optic 110 at and near the optic edge 140, the overall volume of the IOL 100 can be reduced (thickness is measured anterior-posterior along the optical axis (OA)). For example, the thickness of the optic 110 at its most central point, the optical center 160 (the point of maximum thickness for a biconvex lens), can be 0.2 mm to 2 mm, while the optic edge 140 can have a thickness of 0.05 mm to 0.3 mm. The thickness of the optic 110 can vary based on the material used for the optic 110. For example, a relatively stiff material can have an optic edge 140 with a thickness of 0.05 mm to 0.1 mm, while a relatively soft material can have an optic edge 140 with a thickness of 0.1 mm to 0.3 mm. The maximum thickness of the optic 110 may be less than the thickness of the haptics 120 (measured along the optical axis of the optic).

[0018] One or more haptics 120 connect the optic 110 to the capsular bag and hold the optic 110 in a stable position within the capsular bag. While the embodiment shown in FIGS. 1A-1D depicts an IOL with two open-loop haptics, the number and shape of the haptics can vary. The number of haptics can include, but is not limited to, one, two, three, four, five, or six. The shape of the haptics can include, but is not limited to, plate haptics, open-loop haptics such as C-loops or J-loops, angled loop haptics, planar loop haptics, or offset haptics. The overall length of the IOL 100 with haptics can be between 10 mm and 15 mm. The thickest part of the haptics 120 (measured along an axis parallel to the optical axis of the lens) can be between 0.2 mm and 1 mm. For example, the thickest part of the haptics 120 can be 0.6 mm.

[0019] Gussets 130 (shown in more detail in FIGS. 1C and 1D ) attach the optic 110 to the two haptics 120. Each gusset 130 extends radially inward from the haptics 120, across the optic edge 140, toward the optical center 160, such that the gusset 130 extends at least partially overlapping the anterior surface of the optic 110. Each gusset 130 has a radially innermost edge 150 that is located on the anterior surface of the IOL 100, radially inward from where the optic edge 140 would be if the gusset 130 were not present. The radially innermost edges 150 of the gussets 130 may be between 2.5 mm and 3 mm radially outward from the optical center 160 to prevent obstruction of the patient's vision. For example, the radially innermost edge 150 of the gusset 130 can be 2.75 mm radially outward from the optical center 160 in some embodiments, with the distance across the optic from one gusset edge 150 to the other gusset edge 150 being 5.5 mm. The radially innermost edge 150 of the gusset 130 can be 0.1 to 1.5 mm radially inward from the distance corresponding to the optic's edge 140 (i.e., where the optic's edge 140 would be if the gusset 130 were absent). For example, the radially innermost edge 150 of the gusset 130 can be 1.25 mm radially inward from the optic's edge 140.

[0020] In some examples, the optical surface profile defining the optically active area (e.g., spherical monofocal or aspheric monofocal profile, multifocal profile, or extended depth of focus surface profile) of the anterior and / or posterior surface of the optic 110 can extend continuously from the optical center 160 to the optic edge 140 (except for the area where the gusset 130 impinges). In other examples, the optical surface profile defining the optically active area of ​​the anterior and / or posterior surface can extend radially from the optical center 160 by the distance between the optical center 160 and the optic edge 140, e.g., approximately 2.5 mm to 3 mm radially from the optical center 160. In such examples, the peripheral region 115 of the anterior surface outside the optical surface profile can have a different surface profile than the central region of the optic 110. For example, the profile of the peripheral region 115 can be flat or can have a different thickness than the optical surface profile. In embodiments that include a peripheral region 115, the peripheral region 115 may be separated from the optically active region by a boundary 118, which may or may not be visually perceptible. In embodiments that do not include a peripheral region 115, the boundary 118 does not exist.

[0021] The gusset 130 may vary in thickness between the radially innermost edge 150 and the haptics 120. The radially innermost edge 150 may be level or flush with the optic 110, with the radially innermost edge 150 having a thickness of zero. As the gusset 130 extends from the radially innermost edge 150 radially outward from the optical center 160, the thickness of the gusset 130 may increase monotonically. The thickness may continue to increase to a first peak thickness 135 located at a point radially outward from the optic edge 140.

[0022] In conventional IOLs, the haptics are connected to the optic at a haptic-optic junction along the periphery of the optic's edge. This design requires a threshold edge thickness for stability of this connection. Due to the required edge thickness, extending the optic to a relatively large diameter (e.g., greater than 6 mm) increases the volume to an extent that makes small incision delivery difficult or impossible (e.g., a 2 mm to 3 mm incision or smaller).

[0023] However, in the disclosed design, the gussets 130 connecting the optic 110 and haptics 120 at least partially overlap the anterior and / or posterior surfaces of the optic 110, thus using a portion of the anterior surface for haptic-optic connection, rather than just around the edge of the optic. Thus, the gussets 130 can protrude from the anterior and / or posterior surfaces of the optic. In some instances, the gussets 130 protrude from only one of the anterior or posterior surfaces and are flush with the opposite surface.

[0024] As a result, the diameter of the optic 110 can be increased relative to conventional optics, while the corresponding increase in volume is minimized so that the IOL can be inserted through a small incision. In various examples, the volume of the optic 110 is 10 mm 3 ~40mm 3 It is possible.

[0025] The optic 110 can have a diameter ranging from 6 mm to 8 mm. In some embodiments, the diameter of the optic 110 can be 6 mm, 7 mm, or 8 mm, and the total volume of the IOL is approximately 19 mm. 3 ~about 48mm 3 The thickness of the optical edge 140 may be about 0.05 mm. 3 ~about 0.3mm 3 The range can be:

[0026] In an embodiment where the optic diameter is 6 mm, the optic edge 140 may have a thickness of 0.25 mm. 3 ~23mm 3 For example, a 21 diopter IOL can have a total volume of 19 mm 3 A 30 diopter IOL can have a total IOL volume of 23 mm 3 The total IOL volume may be

[0027] In an embodiment where the optic diameter is 7 mm, the optic edge 140 may have a thickness of 0.1 mm. 3 ~30mm3 For example, a 21 diopter IOL may have a total volume of 23 mm 3 A 30 diopter IOL can have a total IOL volume of 30 mm 3 The total IOL volume may be

[0028] In an embodiment where the optic diameter is 8 mm, the optic edge 140 may have a thickness of 0.1 mm. In this embodiment, the IOL 100 has a 35 mm 3 ~48mm 3 For example, a 21 diopter IOL can have a total volume of 35 mm 3 A 30 diopter IOL can have a total IOL volume of 48 mm 3 The total IOL volume may be

[0029] The IOL100 can be inserted through an incision between 1 mm and 3 mm. Maintaining a small incision is important because a larger incision can lead to a flattening effect on the cornea. Furthermore, a relatively small incision may be better able to seal postoperatively to prevent leakage and tear film contamination. Rapid incision sealing can help prevent or reduce the risk of developing surgically induced astigmatism or endophthalmitis. Because fluid flow is related to the size of the phaco needle, using an incision smaller than 1 mm reduces the flow rate and significantly slows the procedure. Incisions larger than 3 mm tend to have a relatively large flattening effect on the cornea at that meridian. Furthermore, to prevent leakage along with tear film inflow, which can increase the risk of endophthalmitis, the incision should be small enough to seal effectively postoperatively. Therefore, the ideal incision size for cataract surgery is between 1 mm and 3 mm, which is small enough to reduce the astigmatic effect of the incision and the risk of infection due to leakage or tear film contamination.

[0030] The optic 110, haptics 120, and gusset 130 can be made of any material suitable for being a soft and foldable optical material or lens while providing sufficient mechanical support. For example, the material can be a hydrogel, acrylate, or silicone-based material, as known in the field of ophthalmology.

[0031] 2A-2C, the present disclosure relates to an IOL 200 having a ring structure 210 that is integral with the optic 205 and wraps around the periphery of the optic edge 240. The addition of a rigid outer ring structure 210 allows for a relatively thin optic 205, thereby reducing the overall volume of the IOL 200. The optic 205 can be relatively thin because, instead of the optic 205 providing a base and mechanical support, the ring structure 210 provides a base and mechanical support for the haptics 220.

[0032] 2A, IOL 200 is shown having a ring structure 210 around the periphery of optic edge 240. Ring structure 210 can be thicker than optic edge 240 and can be between 0.2 mm and 0.5 mm. For example, ring structure 210 can be 0.3 mm thick.

[0033] The IOL 200 may have a step between the edge of the optic and the ring structure. The shape of the step 200 is not limited and may be angled, vertical, square, or round.

[0034] Multiple haptics 220 can be attached to the ring structure 210 on opposite sides at haptic-ring junctions. At the connection 230 (shown in FIG. 2C), the haptic-ring junction can be the same thickness as the ring structure thickness, then increase in thickness from the ring structure thickness to a point radially beyond the ring structure. The thickness of the haptic-ring junction can increase monotonically as it extends outward. While the embodiment shown in FIG. 2A shows an IOL with two open-loop haptics, the number and shape of the haptics can vary. The number of haptics can include, but is not limited to, two, three, four, five, or six. The shape of the haptics can include, but is not limited to, plate-like haptics, open-loop haptics such as C-loops or J-loops, angled-loop haptics, planar-loop haptics, or offset haptics.

[0035] 2B-2C show a cross section of IOL 200. In some embodiments, the thickness of the optic edge 240 can be between 0.05 mm and 0.3 mm. For example, the thickness of the optic edge 240 can be 0.15 mm. The maximum thickness of the optic 205 at its center 250 can be less than the thickness of the ring structure. The thickness of the optic 205 at its center 250 depends on the power of the IOL, the refractive index of the material, and other IOL geometry. In some embodiments, the thickness of the optic 205 at its center 250 can be between 0.2 mm and 2 mm.

[0036] Reducing the overall thickness of the lens allows for a relatively large optic diameter without increasing volume. Thus, the optic 205 can have a larger diameter than conventional optic diameters while maintaining an acceptable volume that can be inserted through a small incision. The ring structure 210 with a relatively thin optic 205 provides the IOL 200 with a volume that can fit through a small incision. For example, the IOL 200 can be inserted through an incision between 1 mm and 3 mm. The diameter of the optic 205 can be between 6 mm and 8 mm. In some embodiments, the optic diameter is 6 mm, 7 mm, or 8 mm, and the total volume of the IOL 200 is approximately 14 mm. 3 ~48mm3 It can be between.

[0037] In an embodiment where the optic diameter is 6 mm, the optic edge 240 may have a thickness of 0.1 mm. In this embodiment, the IOL 200 has a thickness of 14 mm. 3 ~18mm 3 For example, a 21 diopter IOL can have a total volume of 14 mm 3 and a 30 diopter IOL can have a total IOL volume of 18 mm. 3 The total IOL volume may be

[0038] In an embodiment where the optic diameter is 7 mm, the optic edge 240 may have a thickness of 0.1 mm. 3 ~30mm 3 For example, a 21 diopter IOL can have a total volume of 23 mm 3 and a 30 diopter IOL can have a total IOL volume of 30mm. 3 The total IOL volume may be

[0039] In an embodiment where the optic diameter is 8 mm, the optic edge 240 may have a thickness of 0.1 mm. 3 ~48mm 3 For example, a 21 diopter IOL can have a total volume of 35 mm 3 and a 30 diopter IOL can have a total IOL volume of 48 mm 3 The total IOL volume may be

[0040] The optic 205, ring structure 210, and haptics 220 can be made of the same material. Using the same material throughout the IOL 200 allows the entire IOL 200 to be formed together, eliminating the need for bonding or overmolding components. The material used for the optic 205, ring structure 210, and haptics 220 can be a soft, foldable optical material. This relatively soft material can have a modulus of elasticity of 6 MPa or less at 35° C. For example, the material can be a hydrogel, acrylate, or silicone-based material, as known in the ophthalmic field.

[0041] In another embodiment, as shown in FIGS. 3A-3C , the present disclosure relates to an IOL 300 having a ring structure 310 around the periphery of the optic edge 340, where the optic 305 is a different material from the ring structure 310 and the haptics 320. For example, the optic 305 can be made of a first material, and the ring structure 310 and haptics 320 can be made of a second material. The rigidity of the ring structure 310 can provide support for the softer optic 305. The optic 305 and ring structure 310 can be attached via bonding or overmolding. Bonding or overmolding is a process in which two or more different materials are used in combination to create a single part. For example, the optic 305 can be molded first. Then, the ring structure 310 and haptics 320 can be molded onto or around the optic 305.

[0042] The optic portion 305 can be made of a first material. The optic portion 305 can be made of, for example, a soft, foldable optical material. By way of example, the optic portion 305 can be made of Acrysof®, p-hydroxyethyl methacrylate, a hydrophobic silicone polymer, an acrylate, or a hydrophilic 2-HEMA homopolymer. In some embodiments, the optic portion 305 can be made of a soft acrylate.

[0043] The ring structure 310 and haptics 320 can be made of a second material. For example, the ring structure 310 and haptics 320 can be made of a material with higher stiffness than the optic 305, eliminating the need for a thicker optic edge 340. Using a relatively high stiffness material for the ring structure 310 and haptics 320 can reduce the overall volume of the IOL 300 and facilitate small delivery incisions, allowing the IOL 300 to be inserted through incisions of 1 mm to 3 mm. The ring structure 310 and haptics 320 material can have appropriate strength and stiffness characteristics to provide stability within the capsular bag while remaining foldable and enabling delivery through small incisions within the capsular bag. A relatively high stiffness material resists deformation in response to an applied force compared to a more flexible material. A relatively high stiffness material can have an elastic modulus at least 30% higher than the elastic modulus of a relatively soft material. In some embodiments, the relatively high stiffness material can have a modulus of elasticity of 7.8 MPa or greater at 35° C. The ring structure 310 and haptics 320 can be made of a second material, such as a rigid haptic material, including, for example, poly(methyl methacrylate) (p-MMA), polyvinylidene fluoride (PVDF), polysulfone, acrylic, or any material that is suitably stiff and foldable to support the optic 305.

[0044] In some embodiments, the ring structure 310 and the optic edge 340 can be the same thickness. The ring structure 310 and the optic edge 340 can be between 0.05 mm and 0.25 mm thick. For example, the ring structure 310 and the optic edge 340 can be 0.15 mm thick.

[0045] In other embodiments, the ring structure 310 may be thicker than the optic edge 340. The ring structure 310 may be 0.1 mm to 0.5 mm thick. For example, the ring structure 310 may be 0.15 mm thick. The optic edge 340 may be 0.05 mm to 0.3 mm thick. The ring structure 310 may be 30% to 500% thicker than the optic edge 340.

[0046] The diameter of the optic portion 305 can be between 6 mm and 8 mm. In some embodiments, the diameter of the optic portion 305 can be 6 mm, 7 mm, or 8 mm, and the total volume of the IOL 300 can be 13 mm or less. 3 ~46mm 3 It is possible.

[0047] In an embodiment where the optic diameter is 6 mm, the optic edge 340 may have a thickness of 0.1 mm. 3 ~17mm 3 For example, 21 diopters can have a total volume of 13 mm 3 The total IOL volume of the 30 diopter IOL is 17mm. 3 The total IOL volume may be

[0048] In an embodiment where the optic diameter is 7 mm, the optic edge 340 may have a thickness of 0.1 mm. 3 ~28mm 3 For example, a 21 diopter IOL can have a total volume of 21 mm 3 and a 30 diopter IOL can have a total IOL volume of 28 mm 3 The total IOL volume may be

[0049] In an embodiment where the optic diameter is 8 mm, the optic edge 340 may have a thickness of 0.1 mm. 3 ~46mm 3 For example, a 21 diopter IOL can have a total volume of 34 mm 3 and a 30 diopter IOL has a total IOL volume of 46 mm 3 may have.

[0050] The subject matter disclosed above should be considered illustrative and not restrictive, and the appended claims are intended to encompass all such modifications, improvements, and other embodiments that fall within the true spirit and scope of the present disclosure. Accordingly, to the maximum extent permitted by law, the scope of the present disclosure should be determined by the broadest permissible interpretation of the following claims and their equivalents, and should not be limited or constrained by the above detailed description.

Claims

1. In intraocular lenses (IOLs), The intraocular lens (IOL) is an optic having an anterior surface and a posterior surface surrounded by an optic edge; a plurality of haptics each attached to the optic by a gusset, each gusset extending beyond an edge of the optic toward an optical center such that the gusset at least partially overlaps at least one of the anterior and posterior surfaces of the optic.

2. 10. The intraocular lens (IOL) of claim 1, wherein the gusset varies in thickness between its radially innermost edge and the haptic.

3. 3. An intraocular lens (IOL) according to claim 1 or 2, wherein the gussets increase in thickness as they extend from their radially innermost edges away from the optical center.

4. 4. An intraocular lens (IOL) according to claim 2 or 3, wherein the radially innermost edge of the gusset is at least 2.75 mm from the optical center.

5. The optical portion has a diameter of 6 mm to 8 mm, and the intraocular lens has a diameter of 19 mm. ３ ~48mm ３ An intraocular lens (IOL) according to any one of claims 1 to 4, having a total volume of

6. An intraocular lens (IOL) according to any one of claims 1 to 5, wherein the edge of the optical zone has a thickness of 0.05 mm to 0.3 mm.

7. The optical zone has a diameter of 7 mm, and the intraocular lens has a diameter of 23 mm. ３ ~30mm ３ An intraocular lens (IOL) according to any one of claims 1 to 6, having a total volume of

8. The diameter of the optical portion is 8 mm, and the total volume of the intraocular lens is 35 mm ３ ~48mm ３ The intraocular lens (IOL) according to any one of claims 1 to 6,

9. 9. The intraocular lens (IOL) of claim 1, wherein the at least one of the anterior and posterior surfaces comprises an optically active area configured to focus light to one or more focal points and a peripheral area surrounding the optically active area, and a radially innermost gusset edge is within the peripheral area.

10. An intraocular lens (IOL) according to any one of claims 1 to 9, wherein the gusset protrudes from only one of the anterior and posterior surfaces of the optical portion such that the cross section of the gusset is asymmetric with respect to a plane perpendicular to the optical axis.

11. In intraocular lenses (IOLs), The intraocular lens (IOL) is an optic having an anterior surface and a posterior surface, the optic being centered about an optical axis and surrounded by an optic edge connecting the anterior surface and the posterior surface; a ring structure integral with the optic and surrounding a periphery of the edge of the optic, the ring structure having a first thickness and the edge of the optic having a second thickness, the first thickness being greater than the second thickness; and a plurality of haptics attached to the ring structure.

12. 12. The intraocular lens (IOL) of claim 11, wherein the IOL further comprises a step between the edge of the optic and the ring structure.

13. 13. An intraocular lens (IOL) as described in claim 11 or 12, wherein the haptic and the ring structure are attached at a haptic-ring junction, the haptic-ring junction having a thickness, and the haptic-ring junction increases in thickness from the thickness of the ring structure to a point radially beyond the ring structure.

14. An intraocular lens (IOL) according to any one of claims 11 to 13, wherein the ring structure has a thickness of 0.2 mm to 0.5 mm.

15. An intraocular lens (IOL) according to any one of claims 11 to 14, wherein the optical portion is made of a first material, the ring structure and the support portions are made of a second material, and the second material has a stiffness higher than that of the first material.

16. An intraocular lens (IOL) according to any one of claims 11 to 15, wherein the ring structure and the haptics are molded or bonded to the edge of the optic.

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