Biopolymer formulations for drug delivery

JP2025522924A5Pending Publication Date: 2026-07-0611584022 CANADA INC

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
11584022 CANADA INC
Filing Date
2023-06-29
Publication Date
2026-07-06

AI Technical Summary

Technical Problem

There is a need for new methods of incorporating biopolymers into drug delivery systems (DDS) that are non-toxic, biocompatible, and biodegradable, as conventional biopolymers like cellulose and chitin are insoluble, limiting their use.

Method used

A homogeneous suspension of biopolymers, such as chitin and chitosan, is mechanically treated under high shear conditions to form a stable, homogeneous aqueous composition for drug delivery, retaining hydrophilic and hydrophobic molecules, and can be formulated into pastes, creams, lotions, or gels for controlled release.

Benefits of technology

The biopolymer suspension provides a stable, controlled release of pharmaceutical active ingredients, reducing unwanted interactions and maintaining stability for extended periods, suitable for various administration routes including topical and oral.

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Abstract

This specification describes a formulation comprising a homogeneous suspension of a biopolymer(s) for drug delivery of an active molecule. In an embodiment, the biopolymer is selected from chitin, chitosan, cellulose, hemicellulose, lignin, amylose, actin, fibrin, collagen, silk, fibroin, keratin, wool, alginic acid, and mixtures thereof. In an embodiment, the biopolymer is mechanically treated with an API under high shear conditions and / or high mechanical energy. The formulation can find particular use in drug delivery systems that involve the transport and release of compounds or molecules for purposes such as pharmaceuticals, drug substances, cosmetics, and the like.
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