Compositions and methods for inducing oocyte maturation

Abstract

Methods, compositions, and devices are featured for in vitro maturation of oocytes. In particular, the present disclosure features methods for inducing oocyte maturation in vitro by co-culturing oocytes from a female subject with an in vitro composition containing a plurality of ovarian support cells (e.g., granulosa cells). Additional methods are provided for administering a follicle-inducing agent and for harvesting oocytes from a female subject. Such methods, compositions, and devices are particularly useful for assisted reproductive technology (ART) procedures.

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