Personal care aerosol compositions, methods and devices
The use of trans-1-chloro-3,3,3-trifluoropropene and co-carriers in antiperspirant aerosol sprays addresses delivery challenges, providing a dry, silky feel and targeted application while replacing harmful silicone fluids.
Patent Information
- Application Number
- JP2025173351
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2019-04-01
- Filing Date
- 2025-10-15
- Publication Date
- 2026-01-21
AI Technical Summary
Existing antiperspirant aerosol sprays face challenges in delivering small particles effectively to the skin, with issues such as wide dispersion and particle bounce-off due to high propellant energy, and there is a need to replace volatile silicone fluids like D-4 and D-5 with environmentally safer alternatives that maintain efficacy and feel.
A personal care formulation using trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) as a hydrophobic carrier with co-carriers like triglycerides, esters, and isoparaffins, along with hydrophobized clay and active ingredients, to create a dry, silky feel and targeted spray pattern.
The formulation achieves effective delivery of active ingredients with a dry, silky feel, reducing particle bounce and ensuring targeted application without the use of environmentally harmful silicone fluids.
Smart Images
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Abstract
Description
[Technical Field]
[0001] This application claims priority benefit of U.S. Provisional Application No. 62 / 827,697, filed April 1, 2019, which is incorporated herein by reference.
[0002] FIELD OF THE INVENTION The present invention relates generally to aerosols and methods and devices for delivering aerosols to human skin and / or hair, including antiperspirant and other personal care compositions for delivery via powder suspension-type aerosols suitable for spraying from a pressurized container. [Background technology]
[0003] Antiperspirant compositions generally contain antiperspirant active compounds that chemically inhibit sweat production by sweat glands.One example of such a compound is aluminum chlorohydrate, which acts as an astringent to inhibit sweating in users.Such antiperspirant formulations can be applied to skin using several different application modes, including roll-on and stick forms.However, those skilled in the art will understand that applying antiperspirant formulations in the form of aerosol sprays can have some advantages when applied to skin.
[0004] In aerosol antiperspirant sprays, the antiperspirant active compound is typically suspended as an insoluble powder in a liquid carrier along with a non-aqueous liquefied volatile propellant in a pressurized aerosol container. The aerosol spray is produced by the rapid transition of the propellant from a liquid to a gas phase upon dispensing from the aerosol container's spray valve. As a result, application of antiperspirants using aerosol sprays has become widely accepted for many reasons. Aerosol application of antiperspirant active compounds in the form of a dry powder suspended in a propellant is cosmetically desirable because the antiperspirant can be smoothly and effectively applied to the skin in a dry, comfortable-feeling manner. Furthermore, because the antiperspirant powder does not dissolve in the liquefied propellant medium, the antiperspirant salts do not corrode conventional metal aerosol cans. Summary of the Invention [Problem to be solved by the invention]
[0005] One difficulty associated with antiperspirant aerosol sprays is that the delivery of small particles of antiperspirant active compounds can pose some technical challenges.For example, fine particle sprays can create difficulties in ensuring that a large proportion of the active ingredient is transferred to, retained on, and absorbed by the user's skin.This problem arises because dry powder sprays often tend to disperse widely or form clouds, which prevents many active particles from reaching the target area.In addition, even if the particles reach the target area, the relatively high energy imparted to the particles by the propellant can cause many particles to bounce off the user's skin.To address these problems, it has become common to use anhydrous liquid carrier components to disperse and / or suspend active powders.Then, the fine droplets of the anhydrous carrier can be transferred to the target area in a more well-defined spray pattern, significantly reducing the problem of dry particles bouncing off the user.Certain silicone liquids have been developed to be used as carrier fluids for active ingredients in some personal care compositions, including antiperspirant aerosol sprays. However, there has been a need to reduce or eliminate the use of the volatile silicone fluids octamethylcyclotetrasiloxane [(CH3)2SiO]4, "D-4," and decamethylcyclopentasiloxane [(CH3)2SiO]5, "D-5," which are frequently used in products, resulting in the release of these liquids into the biosphere. For example, see a publication by the Danish Ministry of the Environment entitled "Siloxanes (D3, D4, D5, D6, HMDS) Evaluation of h See the publication "Health Hazards and Proposal of a Health-Based Quality Criterion for Ambient Air Environmental Project No. 1531, 2014." Developing an alternative carrier fluid to silicone fluids used for active ingredients in personal care products, including antiperspirant aerosol spray products, presents significant technical challenges. For example, the alternative fluid must be able to effectively disperse and / or suspend the active compound without reducing the effectiveness of the particles for their intended purpose, such as preventing sweating. In addition, the carrier fluid must meet a difficult-to-achieve combination of characteristics, including the ability to remain as a fine and targeted spray upon transfer to the user's skin and simultaneously contact the skin without imparting either an excessively wet / oily or excessively dry feeling. Developing a new carrier fluid that can simultaneously achieve this combination of characteristics at the same level as that achieved by previously used silicone fluids is a difficult technical challenge.
[0006] Accordingly, the present invention provides a personal care formulation for delivery to human skin in the form of an aerosol, (1) Non-propellant ingredients, (a) about 0.5% to about 80% by weight of at least one active ingredient in particulate form; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier, wherein (i) the weight ratio of said trans-1233zd to said co-carrier is about 0.25:1 to about 4:1, (ii) said trans-1233zd and said co-carrier collectively constitute at least about 40% by weight of said hydrophobic carrier, and (iii) said co-carrier is of a type and present in an amount such that it provides a dry, silky feel to said formulation when sprayed onto human skin in aerosol form; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0007] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 1.
[0008] As used herein, "active ingredient" means a compound or compounds that affect or are intended to affect the personal care of the user, including but not limited to the feel, moisture content, texture, shape, color, or health of the skin or hair.
[0009] As used herein, "dry, silky feel" means a feel on the skin or scalp that is neither too wet nor too dry, as these terms are understood in the art.
[0010] As used herein, the term "interfaced" means that the propellant is in at least contact with the non-propellant component and can directly apply a propellant force to the non-propellant component.
[0011] As used herein, "separated" means that a wall, preferably a flexible wall, separates the non-propellant components from at least a portion of the propellant, as in, for example, a formulation contained in a bag-on-valve configuration.
[0012] As used herein, the term "carrier" refers to the components of the formulation that make up the continuous liquid phase of the formulation (excluding any propellant that may be present in the liquid phase), as well as any components that are present in the continuous liquid phase for the purpose of aiding in the suspension and / or stabilizing the dispersion of the active ingredient.
[0013] The present invention also provides a personal care formulation for delivery to human skin in the form of an aerosol, comprising: (1) Non-propellant ingredients, (a) about 0.5% to about 80% by weight of at least one active ingredient in particulate form; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (C) about 10% to about 85% by weight of a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier, the co-carrier comprising one or more of: (i) a triglyceride of a linear or branched, saturated or unsaturated C8-30 fatty acid; (ii) an ester of at least one C2-C9 monocarboxylic, dicarboxylic, or tricarboxylic acid with at least one linear or branched, saturated or unsaturated alcohol having 1 to 30 carbon atoms; (iii) a C10-C20 isoparaffin; and (iv) a volatile silicone fluid other than D-4 and D-5; wherein the weight ratio of said trans-1233zd to co-carrier is about 0.25:1 to about 4:1, and said trans-1233zd and said co-carrier collectively constitute at least about 40% by weight of said hydrophobic carrier; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0014] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 2.
[0015] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the ingredients in the formulation, comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier, the co-carrier comprising one or more of (i) a triglyceride of a straight or branched chain, saturated or unsaturated C8-30 fatty acid, and (ii) an ester of at least one C2-C9 monocarboxylic acid, dicarboxylic acid, or tricarboxylic acid with at least one straight or branched chain, saturated or unsaturated alcohol having 1 to 30 carbon atoms, the weight ratio of said trans-1233zd to said co-carrier being about 0.25:1 to about 4:1, and said trans-1233zd and said co-carrier collectively comprising at least about 40% by weight of said hydrophobic carrier; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0016] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 3.
[0017] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of one or more triglycerides of straight or branched chain, saturated or unsaturated C8-30 fatty acids, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0018] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 4.
[0019] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier being one or more triglycerides that are natural oils, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0020] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 5.
[0021] As used herein, "natural oil" refers to oil extracted from naturally occurring plant sources.
[0022] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier being selected from the group consisting of the liquid components of soybean oil, cottonseed oil, sunflower oil, palm oil, palm kernel oil, linseed oil, almond oil, castor oil, corn oil, olive oil, rapeseed oil, sesame oil, safflower oil, wheat germ oil, peach kernel oil, coconut oil, and combinations of two or more thereof, wherein the weight ratio of trans-1233zd:first co-carrier is from about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, non-propellant components, the percentages of which are based on the total weight of components (a) through (d) in the formulation; (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0023] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 6.
[0024] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier consisting of safflower oil, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0025] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 7.
[0026] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of an ester of at least one C2 to C7 monocarboxylic acid, dicarboxylic acid, or tricarboxylic acid with at least one straight or branched chain, saturated or unsaturated alcohol having 1 to 30 carbon atoms, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0027] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 8.
[0028] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, a hydrophobic carrier, wherein the co-carrier comprises a diester of at least one C2-C7 dicarboxylic or tricarboxylic acid and at least one linear or branched, saturated or unsaturated alcohol having 4 to 10 carbon atoms, and the weight ratio of said trans-1233zd to first co-carrier is from about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) a propellant for powering said non-propellant components (a)-(d), said propellant being capable of interfacing with and / or separating from said components (a)-(d). For convenience, the personal care formulation according to this paragraph is referred to herein as Formulation 9.
[0029] The present invention also provides a personal care formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, the hydrophobic carrier comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of a diester of at least one C3-C5 dicarboxylic acid or tricarboxylic acid and at least one linear or branched, saturated or unsaturated alcohol having 5 to 9 carbon atoms, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0030] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 10.
[0031] Accordingly, the present invention provides an antiperspirant formulation for delivery to human skin in the form of an aerosol, (1) Non-propellant ingredients, (a) about 0.5% to about 80% by weight of at least one antiperspirant active ingredient in the form of microparticles; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier, wherein (i) the weight ratio of said trans-1233zd to said co-carrier is about 0.25:1 to about 4:1, (ii) said trans-1233zd and said co-carrier collectively constitute at least about 40% by weight of said hydrophobic carrier, and (iii) said co-carrier is of a type and present in an amount such that it provides a dry, silky feel to said formulation when sprayed onto human skin in aerosol form; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0032] For convenience, the antiperspirant formulation according to this paragraph will be referred to herein as Formulation 11.
[0033] The present invention also provides an antiperspirant formulation for delivery to human skin in the form of an aerosol, comprising: (1) Non-propellant ingredients, (a) about 0.5% to about 80% by weight of at least one antiperspirant active ingredient in the form of microparticles; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (C) about 10% to about 85% by weight of a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier, the co-carrier comprising one or more of: (i) a triglyceride of a linear or branched, saturated or unsaturated C8-30 fatty acid; (ii) an ester of at least one C2-C9 monocarboxylic, dicarboxylic, or tricarboxylic acid with at least one linear or branched, saturated or unsaturated alcohol having 1 to 30 carbon atoms; and (iii) a C10-C20 isoparaffin, wherein the weight ratio of said trans-1233zd to said co-carrier is about 0.25:1 to about 4:1, and said trans-1233zd and said co-carrier collectively constitute at least about 40% by weight of said hydrophobic carrier; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with and / or be separated from the components (a) to (d).
[0034] For convenience, the personal care formulation according to this paragraph will be referred to herein as Formulation 12.
[0035] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, wherein the hydrophobic carrier comprises at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of one or more triglycerides of straight-chain or branched-chain, saturated or unsaturated C8-30 fatty acids, and the weight ratio of said trans-1233zd:first co-carrier is about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0036] For convenience, the antiperspirant formulation according to this paragraph will be referred to herein as Formulation 13.
[0037] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of one or more triglycerides that are natural oils, and the weight ratio of said trans-1233zd:first co-carrier is about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0038] For convenience, the antiperspirant formulation according to this paragraph will be referred to herein as Formulation 14.
[0039] As used herein, "natural oil" refers to oil extracted from naturally occurring plant sources.
[0040] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier being selected from the group consisting of soybean oil, cottonseed oil, sunflower oil, palm oil, palm kernel oil, linseed oil, almond oil, castor oil, corn oil, olive oil, rapeseed oil, sesame oil, safflower oil, wheat germ oil, peach kernel oil, coconut oil, and combinations of two or more thereof, and the weight ratio of trans-1233zd:first co-carrier is about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0041] For convenience, the antiperspirant formulation according to this paragraph will be referred to herein as Formulation 15.
[0042] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% by weight to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier consisting of safflower oil of the total carrier components, wherein the weight ratio of said trans-1233zd:first co-carrier is about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) A propellant for imparting power to the non-propellant components (a) to (d), which propellant can interface with or be separated from the components (a) to (d).
[0043] For convenience, the antiperspirant formulation according to this paragraph will be referred to herein as Formulation 16.
[0044] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of an ester of at least one C2 to C7 monocarboxylic acid, dicarboxylic acid, or tricarboxylic acid with at least one straight or branched chain, saturated or unsaturated alcohol having 1 to 30 carbon atoms, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) a propellant for powering said non-propellant components (a)-(d), said propellant being capable of interfacing with and / or separating from said components (a)-(d). For convenience, an antiperspirant formulation according to this paragraph is referred to herein as Formulation 17.
[0045] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of a diester of at least one C2 to C7 dicarboxylic acid or tricarboxylic acid and at least one linear or branched, saturated or unsaturated alcohol having 4 to 10 carbon atoms, the weight ratio of said trans-1233zd to first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) a propellant for powering said non-propellant components (a)-(d), said propellant being capable of interfacing with and / or separating from said components (a)-(d). For convenience, an antiperspirant formulation according to this paragraph is referred to herein as Formulation 18.
[0046] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of a diester of at least one C3-C5 dicarboxylic acid or tricarboxylic acid and at least one linear or branched, saturated or unsaturated alcohol having 5 to 9 carbon atoms, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) a propellant for powering said non-propellant components (a)-(d), said propellant being capable of interfacing with and / or separating from said components (a)-(d). For convenience, an antiperspirant formulation according to this paragraph is referred to herein as Formulation 19.
[0047] The present invention also provides an antiperspirant formulation for delivery in the form of an aerosol, (1) Non-propellant ingredients, (a) about 1% to about 60% by weight of at least one antiperspirant active ingredient; (b) about 0.5% to about 15% of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier, based on the total weight of the components in the formulation, comprising at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) of the total carrier components and at least about 20% by weight of a first co-carrier of the total carrier components, the first co-carrier consisting of a diester of succinic acid and a linear or branched, saturated or unsaturated alcohol having 7 carbon atoms, the weight ratio of said trans-1233zd:first co-carrier being about 0.25:1 to about 4:1; (d) optionally, one or more non-propellant adjuvants, wherein the percentages of said components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) a propellant for powering said non-propellant components (a)-(d), said propellant being capable of interfacing with and / or separating from said components (a)-(d). For convenience, an antiperspirant formulation according to this paragraph will be referred to herein as Formulation 20.
[0048] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd), and (b) at least one co-carrier, wherein (i) the weight ratio of said trans-1233zd to said co-carrier is from about 0.25:1 to about 4:1, and (ii) said co-carrier is of a type and present in an amount such that, when sprayed in aerosol form onto human skin, it provides said personal care composition with a dry, silky feel, and said trans-1233zd and said co-carrier together comprise at least about 90% by weight of said replacement fluid. For convenience, antiperspirant formulations according to this paragraph will be referred to herein as Replacement Fluid 1.
[0049] As used herein, " drop-in " replacement fluid refers to the fluid that can be used in cosmetics as a complete replacement for all silicone fluids that are used in existing formulations.As used herein, complete replacement means that the formulation is essentially free of silicone fluid, and will contain replacement fluid in an amount that is effective to achieve the cosmetic product with the same feel characteristics as the fluid that contains silicone oil.
[0050] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd), and (b) at least one co-carrier selected from (i) a triglyceride of a linear or branched, saturated or unsaturated C8-30 fatty acid, (ii) an ester of at least one C2-C9 monocarboxylic, dicarboxylic, or tricarboxylic acid with at least one linear or branched, saturated or unsaturated alcohol having 1 to 30 carbon atoms, (iii) a C10-C20 isoparaffin, and (iv) a volatile silicone fluid other than D-4 and D-5, wherein the weight ratio of said trans-1233zd to co-carrier is from about 0.25:1 to about 4:1, and said trans-1233zd and said co-carrier together constitute at least about 90% by weight of said replacement fluid. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 2.
[0051] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) trans-1-chloro-3,3,3-trifluoropropene (trans-12 33zd) and and (b) at least one co-carrier selected from (i) a triglyceride of a linear or branched, saturated or unsaturated C8-30 fatty acid, (ii) an ester of at least one C2-C9 monocarboxylic, dicarboxylic, or tricarboxylic acid with at least one linear or branched, saturated or unsaturated alcohol having 1 to 30 carbon atoms, and (iii) a C10-C20 isoparaffin, wherein the weight ratio of said trans-1233zd to said co-carrier is from about 0.25:1 to about 4:1, and said trans-1233zd and said co-carrier together constitute at least about 90% by weight of said replacement fluid. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 3.
[0052] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); and (b) at least about 20% by weight of at least one co-carrier, wherein the first co-carrier is a triglyceride of one or more straight or branched chain, saturated or unsaturated C8 to C30 fatty acids, and the weight ratio of said trans-1233zd:first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 4.
[0053] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); and (b) at least about 20% by weight of at least a first co-carrier, the first co-carrier consisting of one or more triglycerides that are natural oils, wherein the weight ratio of said trans-1233zd:first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 5.
[0054] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); (b) at least about 20% by weight of at least a first co-carrier, the first co-carrier consisting of a liquid component of soybean oil, cottonseed oil, sunflower oil, palm oil, palm kernel oil, linseed oil, almond oil, castor oil, corn oil, olive oil, rapeseed oil, sesame oil, safflower oil, wheat germ oil, peach kernel oil, coconut oil, or a combination of two or more thereof, wherein the weight ratio of said trans-1233zd to said first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Fluid Replacement 6.
[0055] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); and (b) at least about 20% by weight of at least a first co-carrier, the first co-carrier consisting of safflower oil, wherein the weight ratio of said trans-1233zd:first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 7.
[0056] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions. This alternative fluid provides (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); (b) at least about 20% by weight of at least a first co-carrier comprising an ester of at least one C2-C7 monocarboxylic, dicarboxylic, or tricarboxylic acid and at least one straight or branched chain, saturated or unsaturated alcohol having from 1 to 30 carbon atoms, wherein the weight ratio of said trans-1233zd to said first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 8.
[0057] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); (b) at least about 20% by weight of at least a first co-carrier, the first co-carrier consisting of a diester of at least one C2-C7 dicarboxylic or tricarboxylic acid and at least one linear or branched, saturated or unsaturated alcohol having from 4 to 10 carbon atoms, wherein the weight ratio of said trans-1233zd to first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 9.
[0058] The present invention also provides a drop-in replacement fluid for silicone fluids in personal care compositions, the replacement fluid comprising: (a) at least about 20% by weight of trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd); (b) at least about 20% by weight of at least a first co-carrier, the first co-carrier consisting of a diester of at least one C3-C5 dicarboxylic or tricarboxylic acid and at least one linear or branched, saturated or unsaturated alcohol having 5 to 9 carbon atoms, wherein the weight ratio of said trans-1233zd to first co-carrier is from about 0.25:1 to about 4:1. For convenience, antiperspirant formulations according to this paragraph are referred to herein as Replacement Fluid 10.
[0059] The present invention also provides drop-in replacement fluids for silicone fluids in antiperspirant formulations, including the use of each of Replacement Fluids 1-10 as a drop-in replacement for D-4 or D-5 in antiperspirant formulations.
[0060] The present invention also provides a method for applying a personal care formulation in the form of an aerosol to a person, comprising: (A) providing a container with a personal care composition of the present invention comprising each of Formulations 1-10; (B) applying at least the non-propellant components of the personal care composition to the person.
[0061] The present invention also provides a method for applying an antiperspirant formulation in aerosol form to a person, comprising: (A) providing a container with a personal care composition of the present invention comprising each of Formulations 11-20; (B) applying at least the non-propellant components of the personal care composition to the person.
[0062] Thus, the present invention also provides a method for delivering a personal care formulation to human skin. Also provides (a) providing a container for containing a personal care formulation of the present invention comprising each of Formulations 1-10; (b) controllably releasing at least a portion of the formulation in the container in the form of an aerosol to produce a spray containing at least a portion of the personal care formulation.
[0063] Accordingly, the present invention also provides a method for delivering an antiperspirant to human skin, comprising: (a) providing a container for containing an antiperspirant formulation of the present invention containing each of formulations 11-20; (b) controllably releasing at least a portion of the formulation in the container in the form of an aerosol to produce a spray containing at least a portion of the antiperspirant formulation.
[0064] Accordingly, the present invention also provides a device for delivering a personal care formulation to human skin, comprising: (a) a container for containing the personal care formulations of the present invention, including each of Formulations 1-10; (b) a valve for controllably releasing at least a portion of said formulation in said container in the form of an aerosol to produce a spray containing at least a portion of said personal care formulation. For convenience, the device according to this paragraph will be referred to herein as Device 1.
[0065] Accordingly, the present invention also provides a device for delivering an antiperspirant to human skin, comprising: (a) a container for containing the antiperspirant formulation of the present invention containing each of Formulations 11 to 20; (b) a valve for controllably releasing at least a portion of said formulation in said container in the form of an aerosol to produce a spray containing at least a portion of said antiperspirant formulation. For convenience, a device according to this paragraph will be referred to herein as Device 2. One example of a device useful according to the present invention is disclosed in U.S. Patent No. 5,082,652, which is incorporated herein by reference. [Example]
[0066] Comparative Example 1 Formulations representative of commercially available antiperspirant products are obtained and tested as set forth in Table C1 below. [Table 1]
[0067] The formulation has spray characteristics representative of commercial antiperspirant aerosol products based on D-5 and has an acceptable dry, silky feel on the skin representative of commercial antiperspirant aerosol products based on D-5. Comparative Example 2
[0068] The same formulations as shown in Table C1 were prepared except that trans-1233zd was used, on an equal weight basis, in place of D-5, as shown in Table C2 below. [Table 2]
[0069] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increases in viscosity as mixing continues. Next, ingredient 5 is added while continuing to mix. Mixing was continued for an additional 5 minutes, gradually increasing the viscosity. Next, the mixture of ingredients 1, 2, 4, and 5 in the beaker was added to a sealable container containing Trans-1233zd, which had been cooled to a temperature below 19°C. The container was then sealed, and mixing was continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30 to 60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, which was then sealed, and the propellant (ingredient 6) was then filled into the can.
[0070] The formulation is tested by spraying it onto the skin of a user.The formulation has generally acceptable spray properties similar to those of the representative commercial antiperspirant aerosol product based on D-5 described in Comparative Example C1, but based on the results of Example C1, it has a much drier feel on the skin than the commercial antiperspirant aerosol product D-5. Example 1
[0071] The same formulations as shown in Table C1 were prepared, except that a 25:75 weight ratio mixture of trans-1233zd and safflower oil was used in place of D-5, on an equal weight basis, as shown in Table 1 below. [Table 3]
[0072] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker was then added to a sealable container containing ingredient 3A (Trans-1233zd) that had been cooled to a temperature below 19°C. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, sealed, and the propellant (ingredient 6) was then filled into the can.
[0073] The formulations are tested by spraying them onto the skin of users. The formulations have acceptable spray characteristics similar to those of a representative commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and are comparable to the commercial D-5 antiperspirant aerosol product compared to the results of Example C1. or better feel on the skin. Example 2
[0074] The same formulations as shown in Table C1 were prepared, except that a 50:50 weight ratio mixture of trans-1233zd and safflower oil was used in place of D-5, on an equal weight basis, as shown in Table 2 below. [Table 4]
[0075] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker was then added to a sealable container containing ingredient 3A (Trans-1233zd) that had been cooled to a temperature below 19°C. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, sealed, and the propellant (ingredient 6) was then filled into the can.
[0076] The formulation is tested by spraying it onto the skin of a user.The formulation has acceptable spray properties similar to those of a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and has a skin feel comparable to or better than that of the commercial D-5 antiperspirant aerosol product, as compared with the results of Example C1. Example 3
[0077] The same formulations as shown in Table C1 were prepared, except that a 75:25 weight ratio mixture of trans-1233zd and safflower oil was used in place of D-5, on an equal weight basis, as shown in Table 3 below. [Table 5]
[0078] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker was then added to a sealable container containing ingredient 3A (Trans-1233zd) that had been cooled to a temperature below 19°C. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, sealed, and the propellant (ingredient 6) was then filled into the can.
[0079] The formulation is tested by spraying it onto the skin of a user.The formulation has acceptable spray properties similar to those of a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and has a skin feel comparable to or better than that of the commercial D-5 antiperspirant aerosol product, as compared with the results of Example C1. Comparative Example 3
[0080] The same formulations as shown in Table C1 were prepared except that safflower oil was used in place of D-5, on an equal weight basis, as shown in Table C3 below. [Table 6]
[0081] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3, 4, and 5 from the beaker was then added to a sealable container. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, and after sealing the can, the propellant (ingredient 6) was filled into the can.
[0082] The formulation is tested by spraying it onto the skin of a user. The formulation is found to have substantially inferior spray properties to a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, i.e., the spray is wet and has a high level of fluidity. Comparative Example 4 - Diheptyl succinate Lex-Feel N-20 replaces D-5
[0083] The same formulations as shown in Table C1 were prepared, except that, on an equal weight basis, a diheptyl succinate-based carrier sold under the trade name Lex-Feel N-20 was used in place of D-5, as shown in Table C4 below. [Table 7]
[0084] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3, 4, and 5 from the beaker was then added to a sealable container. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, and after sealing the can, the propellant (ingredient 6) was filled into the can.
[0085] The formulation is tested by spraying on the skin of the user.The formulation has substantially inferior spray characteristics compared to the typical commercial antiperspirant aerosol product based on D-5 described in Comparative Example C1, that is, the spray has some powder agglomeration.In addition, the feel of the formulation is substantially inferior to the typical commercial antiperspirant aerosol product based on D-5 described in Comparative Example C1, that is, the formulation has wet feel and has poor high level of fluidity. Example 4-50: Replacement of D-5 with 50 trans-1233zd and Lex-Feel N-20
[0086] The same formulations as shown in Table C1 were prepared, except that a 50:50 weight ratio mixture of trans-1233zd and Lex-feel N-20 was used, on an equal weight basis, in place of D-5, as shown in Table 4 below. [Table 8]
[0087] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker was then added to a sealable container containing ingredient 3A (Trans-1233zd) that had been cooled to a temperature below 19°C. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, sealed, and the propellant (ingredient 6) was then filled into the can.
[0088] The formulation is tested by spraying it onto the skin of a user.The formulation has acceptable spray properties similar to those of a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and has a skin feel comparable to or better than that of the commercial D-5 antiperspirant aerosol product, as compared with the results of Example C1. Comparative Example 5 - Replacement of D-5 with Diheptyl Succinate in Lex-Feel N-7
[0089] The same formulations as shown in Table C1 were prepared, except that a diheptyl succinate-based carrier sold under the trade name Lex-Feel N-7 (which has a lower viscosity than N-20) was used on an equal weight basis in place of D-5, as shown in Table C5 below. [Table 9]
[0090] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3, 4, and 5 from the beaker was then added to a sealable container. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, and after sealing the can, the propellant (ingredient 6) was filled into the can.
[0091] Preparation is tested by spraying on user's skin.Preparation has the same spray characteristics as the typical commercial antiperspirant aerosol product based on D-5 described in Comparative Example C1.However, in terms of skin feel, preparation is substantially inferior to the typical commercial antiperspirant aerosol product based on D-5 described in Comparative Example C1, that is, preparation has very oily feel. Example 5-50: Replacement of D-5 with trans-1233zd and Lex-Feel N-7
[0092] The same formulations as shown in Table C1 were prepared, except that a 50:50 weight ratio mixture of trans-1233zd and Lex-feel N-7 was used, on an equal weight basis, in place of D-5, as shown in Table 5 below. [Table 10]
[0093] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker was then added to a sealable container containing ingredient 3A (Trans-1233zd) that had been cooled to a temperature below 19°C. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, sealed, and the propellant (ingredient 6) was then filled into the can.
[0094] The formulation is tested by spraying it onto the skin of a user.The formulation has acceptable spray properties similar to those of a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and has a skin feel comparable to or better than that of the commercial D-5 antiperspirant aerosol product, as compared with the results of Example C1. Example 5
[0095] The same formulations as shown in Table C1 were prepared, except that a 75:25 weight ratio mixture of trans-1233zd and safflower oil was used in place of D-5, on an equal weight basis, as shown in Table 3 below. [Table 11]
[0096] The formulations were prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increased in viscosity as mixing continued. Next, ingredient 5 was added while mixing continued, and the viscosity continued to increase gradually with continued mixing for an additional 5 minutes. The mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker was then added to a sealable container containing ingredient 3A (Trans-1233zd) that had been cooled to a temperature below 19°C. The container was then sealed and mixing continued until the contents were uniform, after which the mixture was allowed to equilibrate for approximately 30-60 minutes. The resulting liquid concentrate mixture was added to a sealable aluminum spray can, sealed, and the propellant (ingredient 6) was then filled into the can.
[0097] The formulation is tested by spraying it onto the skin of a user.The formulation has acceptable spray properties similar to those of a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and has a skin feel comparable to or better than that of the commercial D-5 antiperspirant aerosol product, as compared with the results of Example C1. Example 6
[0098] The same formulations as shown in Table C1 were prepared, except that instead of D-5, a 25:75 weight ratio mixture of trans-1233zd and each of the ingredients identified in Table 6B was used, on an equal weight basis, as shown in Table 6A below. [Table 12] [Table 13]
[0099] The formulation is prepared by first adding the labeled amounts of ingredients 1, 2, 3B, and 4 to a beaker and then mixing these ingredients using a rotor-stator mixer until uniform. The mixture increases in viscosity as mixing continues. Next, ingredient 5 is added while continuing mixing, and the viscosity continues to increase gradually while continuing mixing for an additional 5 minutes. Next, the mixture of ingredients 1, 2, 3B, 4, and 5 from the beaker is added to a sealable container containing ingredient 3A (Trans-1233zd) that has been cooled to a temperature below 19°C. The container is then sealed and mixing continues until the contents are uniform, after which the mixture is allowed to equilibrate for approximately 30 to 60 minutes. The resulting liquid concentrate mixture is added to a sealable aluminum spray can, and after sealing the can, the propellant (ingredient 6) is filled into the can.
[0100] The formulation is tested by spraying it onto the skin of a user.The formulation has acceptable spray properties similar to those of a typical commercial antiperspirant aerosol product based on D-5, as described in Comparative Example C1, and has a skin feel comparable to or better than that of the commercial D-5 antiperspirant aerosol product, as compared with the results of Example C1.
Claims
1. 1. A personal care formulation for delivery to human skin in the form of an aerosol, comprising: (1) Non-propellant components, (a) from about 0.5% to about 80% by weight of at least one active ingredient in particulate form; (b) from about 0.5% to about 15% by weight of at least one hydrophobized clay; (c) about 10% to about 85% by weight of a hydrophobic carrier comprising trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) and at least one co-carrier, (i) the weight ratio of said trans-1233zd to said co-carrier is about 0.25:1 to about 4:1, and (ii) said trans-1233zd and said co-carrier collectively constitute at least about 40% by weight of said hydrophobic carrier; (d) optionally one or more non-propellant adjuvants, wherein the percentages of components (a)-(d) are based on the total weight of components (a)-(d) in the formulation; and (2) a propellant for imparting power to the non-propellant components (a)-(d), wherein the propellant is capable of interfacing with and / or separating from the components (a)-(d).
2. The at least one co-carrier is (i) a linear or branched, saturated or unsaturated C ８～３０ (ii) a triglyceride of a fatty acid; ２ ~C ９ (iii) C esters of monocarboxylic, dicarboxylic or tricarboxylic acids with at least one linear or branched, saturated or unsaturated alcohol having 1 to 30 carbon atoms; １０ ~C ２０ 10. The formulation of claim 1, comprising one or more of: (i) an isoparaffin; (ii) a volatile silicone fluid other than D-4 and D-5; and (iii) a volatile silicone fluid other than D-4 and D-5; and combinations of two or more thereof.
3. 10. The formulation of claim 1, wherein the co-carrier is of a type and present in an amount that provides the formulation with a dry, silky feel when sprayed onto the person's skin in aerosol form.
4. The at least one co-carrier comprises at least about 20% by weight of all the carrier components and is selected from the group consisting of one or more linear or branched, saturated or unsaturated C ８～３０ 10. The formulation of claim 1, consisting essentially of triglycerides of fatty acids and combinations of two or more thereof.
5. 5. The formulation of claim 4, wherein the hydrophobic carrier comprises at least about 20% trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd) by weight of all the carrier components.
6. 10. The formulation of claim 1, wherein the at least one co-carrier consists essentially of one or more triglycerides that are natural oils.
7. 10. The formulation of claim 1, wherein the at least one co-carrier comprises safflower oil present in an amount of at least about 20% by weight based on all the carrier components.
8. 1. A drop-in replacement fluid for silicone fluids in personal care compositions, said replacement fluid comprising: (a) trans-1-chloro-3,3,3-trifluoropropene (trans-1233zd), (b) at least one co-carrier, wherein (i) the trans-1233zd:co-carrier weight ratio is from about 0.25:1 to about 4:1, and (ii) the trans-1233zd and the co-carrier together constitute at least about 90% by weight of the replacement fluid. In-alternative fluids.
9. The at least one co-carrier is (i) a linear or branched, saturated or unsaturated C ８～３０ (ii) a triglyceride of a fatty acid; ２ ~C ９ (iii) C esters of monocarboxylic, dicarboxylic or tricarboxylic acids with at least one linear or branched, saturated or unsaturated alcohol having 1 to 30 carbon atoms; １０ ~C ２０ 9. The drop-in replacement fluid of claim 8, comprising one or more of: (i) an isoparaffin; (ii) a volatile silicone fluid other than D-4 and D-5; and (iii) a volatile silicone fluid other than D-4 and D-5; and combinations of two or more thereof.
10. 9. The drop-in replacement fluid of claim 8, wherein said at least one co-carrier is present in an amount of at least about 20% by weight based on all said carrier components.