Adjusting the moisture level for ophthalmic laser ablation surgery

Abstract

It provides moisture level adjustment for ophthalmic laser ablation surgery. [Solution] In a particular embodiment, the ophthalmic laser ablation system includes a laser device, a fluid removal device, and a computer. The laser device directs laser radiation towards the eye as multiple shots to cut the eye tissue according to a treatment pattern. The fluid removal device removes fluid from the surface of the eye tissue. The computer identifies a moisture retention procedure, instructs the fluid removal device to remove fluid from the surface of the tissue at a certain location in the eye according to the moisture retention procedure, and instructs the laser device to cut the tissue at that location in the eye according to the treatment pattern.

Description

Technical Field

[0001] The present disclosure generally relates to ophthalmic laser ablation systems, and more particularly to the adjustment of the moisture state for ophthalmic laser ablation surgery.

Background Art

[0002] Laser photoablation, or laser ablation, is a process of removing matter from a surface by irradiating it with a laser beam. In ophthalmic surgery, ablation surgery typically uses an excimer laser to deform the cornea and change its refractive properties. The excimer laser beam is directed towards the cornea according to a treatment pattern. The beam separates the molecules from each other, removing the matter, and obtaining the desired corneal shape.

[0003] There are various types of laser ablation procedures. In laser in-situ keratomileusis (LASIK), the cornea is incised to form a flap, and then the cornea is ablated using an excimer laser. Photo refractive keratectomy (PRK) is similar to LASIK, but differs in that instead of forming a flap, the corneal epithelium is removed, for example, chemically or mechanically.

[0004] During laser ablation procedures, the eye is kept open by an eyelid retractor to prevent blinking during the procedure. Originally, the tear layer protects the eye from damage. Since evaporation of the tears leads to loss of this innate protection, the eye is moistened with eye drops to retain the tear layer on its surface.

Summary of the Invention

Means for Solving the Problems

[0005] In certain embodiments, an ophthalmic laser ablation system includes a laser device, a fluid removal device, and a computer. The laser device directs laser radiation towards the eye as multiple shots to cut the eye tissue according to a treatment pattern. The fluid removal device removes fluid from the surface of the eye tissue. The computer identifies a fluid retention procedure and instructs the fluid removal device to remove fluid from the surface of the tissue at a certain location in the eye according to the fluid retention procedure, and instructs the laser device to cut the tissue at that location in the eye according to the treatment pattern.

[0006] The embodiments may include none, one, some, or all of the following features:

[0007] The liquid removal device includes an ultrasonic emitter that generates ultrasonic waves to displace the liquid.

[0008] The liquid removal device includes an infrared emitter that generates infrared radiation to dry the liquid.

[0009] The liquid removal device includes a laser source that generates a laser beam for drying the liquid.

[0010] The liquid removal device includes a device that generates spray air for drying the liquid.

[0011] Fluid retention treatments are identified based on the treatment pattern.

[0012] The liquid is removed before each shot or series of shots.

[0013] The ophthalmic laser ablation system further includes a liquid dispenser that applies liquid to the surface of the tissue. The computer further instructs the liquid dispenser to apply liquid to the surface of the tissue at that location in the eye according to a hydration procedure.

[0014] A liquid dispenser includes a sprayer that atomizes the liquid onto the surface of the tissue.

[0015] A liquid dispenser includes a cannula for injecting liquid into the surface of tissue.

[0016] The liquid is applied after each shot or a series of shots.

[0017] The removed fluid is then reapplied to the surface of the tissue at that location in the eye.

[0018] A liquid with a strong cooling effect or a liquid for wound healing is applied. Alternatively, a liquid with a strong cooling effect is applied, followed by a liquid for wound healing.

[0019] In a particular embodiment, the ophthalmic laser ablation method includes: directing laser radiation towards the eye as multiple shots to cut the eye tissue according to a treatment pattern using a laser device; removing in-situ fluid from the surface of the eye tissue using a fluid removal device; and using a computer to identify a moisture retention procedure, instruct the fluid removal device to remove in-situ fluid from the surface of the tissue at a certain location in the eye according to the moisture retention procedure, and instructing the laser device to cut the tissue at that location in the eye according to the treatment pattern.

[0020] The embodiments may include none, one, some, or all of the following features:

[0021] Fluid retention treatments are identified based on the treatment pattern.

[0022] The liquid dispenser applies liquid to the surface of the tissue. The computer instructs the liquid dispenser to apply liquid to the surface of the tissue at that location in the eye according to the moisture retention procedure.

[0023] The removed fluid is then reapplied to the surface of the tissue at that location in the eye.

[0024] A liquid with a strong cooling effect is then applied, followed by a liquid for wound healing.

[0025] In certain embodiments, an ophthalmic laser ablation system includes a laser device, a liquid removal device, a liquid dispenser, and a computer. The laser device directs laser radiation as a plurality of shots to the eye for cutting eye tissue according to a treatment pattern. The liquid removal device removes liquid from the surface of the eye tissue. The liquid dispenser applies liquid to the surface of the tissue. The computer identifies a moisture retention treatment from the treatment pattern and instructs the liquid removal device to remove the liquid present on-site from the surface of the tissue at a location of the eye to the outside according to the moisture retention treatment, the liquid being removed before each shot or a series of shots, instructs the laser device to cut the tissue at that location of the eye according to the treatment pattern, instructs the liquid dispenser to apply more liquid to the surface of the tissue at that location of the eye according to the moisture retention treatment, and the liquid is applied after each shot or a series of shots. Applying more liquid includes applying a liquid with a strong cooling effect, reapplying the removed liquid to the surface of the tissue at that location of the eye, and applying a liquid for wound healing.

Brief Description of the Drawings

[0026] [Figure 1] FIG. 1 shows an example of an ophthalmic laser ablation system for adjusting the moisture state of a target eye. [Figure 2] FIG. 2 shows an example of a liquid removal device and a liquid dispenser that may be used in the system of FIG. 1. [Figure 3] FIG. 3 shows an example of a method for managing an appropriate moisture state during ophthalmic surgery that may be used by the system of FIG. 1. [Figure 4] FIG. 4 shows an example of a method for managing an appropriate moisture state during ophthalmic surgery that may be used by the system of FIG. 1.

Modes for Carrying Out the Invention

[0027] Next, exemplary embodiments of the disclosed apparatus, systems, and methods are described in detail with reference to the description and drawings. The description and drawings are not intended to be exhaustive or to limit the claims to any particular embodiment shown in the drawings and disclosed in the description. The drawings represent possible embodiments, but they are not necessarily to scale, and certain features may be simplified, exaggerated, omitted, or partially divided to better illustrate the embodiments.

[0028] During laser ablation, the eye is lubricated with eye drops to maintain the tear film on the ocular surface. However, the fluid can disrupt the energy flux of the laser beam. As the beam passes through the fluid, energy is lost, preventing the beam from cutting the tissue. To address this problem, the embodiments described here remove at least a portion of the fluid immediately before ablation to avoid energy loss, and then apply more fluid after ablation to protect the eye.

[0029] Figure 1 shows an example of an ophthalmic laser ablation system 10 according to a specific embodiment, which adjusts the moisture state of a target eye 22 while ablating the tissue of the eye 22. In the example shown, the system 10 includes a laser device 15, a camera 38, a liquid removal device 40, a liquid dispenser 42, and a control computer 30, which are coupled as shown. The laser device 15 includes controllable components such as a laser source 12, a scanner 16, one or more optical elements 17, and / or a focusing objective lens 18, coupled as shown. The computer 30 includes logic 36, memory 32 (for storing computer programs 34), and a display 37, coupled as shown. For ease of explanation, the following xyz coordinate system is used: the z direction is defined by the propagation direction of the laser beam, and the xy plane is perpendicular to the propagation direction. Other suitable xyz coordinate systems may be used.

[0030] In general, the computer 30 instructs the components of the system 10 to adjust the moisture state of the eye 22 according to the following example of operation so that the laser beam of the laser device 15 can perform treatment on the eye 22 according to a treatment pattern. In this example, the laser device 15 is configured to direct the laser radiation towards the eye 22 as laser shots to cut the tissue of the eye 22 according to a treatment pattern. A fluid removal device 40 is configured to remove in-situ fluid from the surface of the eye tissue to the outside, and a fluid dispenser 42 is configured to apply more fluid to the surface of the tissue. The computer 30 identifies a moisture retention treatment. The computer 30 then instructs the components to remove in-situ fluid from the tissue at a certain location in the eye, cut the tissue at that location according to a treatment pattern, and apply more fluid to the tissue at that location according to a moisture retention treatment.

[0031] Next, looking at the components of system 10, the laser source 12 generates a laser beam that cuts the tissue of the eye 22 according to a treatment pattern. The laser source 12 may be an excimer laser that generates a laser beam with a wavelength of less than 300 nm. The treatment pattern may be a shot pattern that defines the x,y (and possibly z) coordinates with respect to the shot position to which the laser emission pulses will be directed. The treatment pattern may be determined from an ablation profile, which indicates the volume of tissue to be removed at a specific x,y position on the cornea. Considering the volume of tissue that one pulse cuts, the number of pulses that will be directed to a certain x,y position can be easily calculated from the volume of tissue defined by the ablation profile.

[0032] The scanner 16 guides the laser beam to focus in the short and long directions. The short direction refers to the direction perpendicular to the beam propagation direction, i.e., the x,y directions. The scanner 16 can guide the laser beam in the short direction by any suitable method. For example, the scanner 16 may include a pair of galvanometrically operated scanner mirrors that can tilt around mutually perpendicular axes. As another example, the scanner 16 may include an electro-optic crystal that can manipulate the laser beam electro-optically.

[0033] The longitudinal direction refers to the direction parallel to the propagation direction of the laser beam, i.e., the z-direction. The scanner 16 can guide the laser beam longitudinally in any suitable manner. For example, the scanner 16 may include a longitudinally adjustable lens, a lens with variable refractive power, or a deformable mirror that can control the z-position of the beam focus. The components of the scanner 16 may be arranged along the beam path in any suitable manner, for example, in the same or different modular units.

[0034] One (or more) optical elements 17 guide the laser beam toward the focusing objective system 18. The optical elements 17 can act on the laser beam (e.g., by transmission, reflection, refraction, diffraction, collimation, adjustment, shaping, focusing, modulation, and / or other actions). Examples of optical elements include lenses, prisms, mirrors, diffractive optical elements (DOEs), holographic optical elements (HOEs), and spatial light modulators (SLMs). In this example, the optical element 17 is a mirror. The focusing objective system 18 focuses the laser beam toward a single point in the eye 22 through the patient interface 20. In this example, the focusing objective system 18 is an objective lens, for example, an fθ objective system.

[0035] Camera 38 records images of the eye 22 via the patient interface 20. Examples of camera 38 include video, optical coherence tomography, or eye-tracking cameras. Camera 38 delivers image data representing the recorded images of the eye 22 to computer 30. Computer 30 may perform image processing on the image data to identify the amount of fluid on the eye 22. Image processing may include recognizing fluid in the recorded images and determining the amount of fluid.

[0036] The liquid removal device 40 removes any liquid present on the surface of the eye 22 to the outside. The liquid may include tears (i.e., tears) and any liquid previously applied to the eye 22. The liquid dispenser 42 applies more liquid to the surface of the eye 22. The liquid dispenser 42 may apply any liquid suitable for treatment of the eye, such as saline solution and / or tears. The liquid may contain additives such as drugs (e.g., analgesics), coolants, disinfectants (e.g., antibacterial agents), and / or volatile components (e.g., alcohol). The liquid removal device 40 and the liquid dispenser 42 will be described in more detail with reference to Figure 2.

[0037] The computer 30 controls the components of the system 10 according to the computer program 34. For example, the computer 30 controls the components (e.g., the laser source 12, the scanner 16, the optical element 17, and / or the focusing objective lens 18) to focus the laser beam of the laser device 15 onto the eye 22 and cut at least a portion of the eye 22 according to the treatment pattern. For the treatment of the eye 22 to be successful, the eye 22 should be in an appropriate moisture state. To properly moisten the eye 22, the computer 30 instructs the components to remove and add fluid to the eye 22 according to the moisture retention procedure.

[0038] The moisture retention treatment may consist of any suitable steps, in any suitable order, sequentially or simultaneously. For example, the treatment may involve removing liquid before one or more shots and / or applying liquid after one or more shots. As another example, the treatment may involve simultaneously removing liquid from the area to be cut next and applying liquid to other areas that will not be cut next.

[0039] In the moisture retention treatment, any appropriate portion of the liquid may be removed. For example, the treatment may remove the liquid only from the area of ​​the next shot, from the area of ​​the next shot and its surrounding area, from a portion of the laser cutting area, or from the entire laser cutting area. As another example, the treatment may remove only a portion of the liquid in a certain area, or it may remove all of the liquid in a certain area.

[0040] In a moisture retention procedure, the fluid may be applied by any suitable method. For example, the procedure may involve applying fresh fluid from a storage area. In another example, the procedure may involve removing the fluid from the eye and then reapplying the removed fluid to the eye, thereby reusing the fluid. In yet another example, the procedure may involve moving the fluid from one area of ​​the eye to another, without the need for removal and reapplication of the fluid. In yet another example, the procedure may involve applying different types of fluids, such as a fluid with a stronger cooling effect (e.g., a highly volatile fluid) or a fluid for wound healing (e.g., a protective or medicinal fluid). In yet another example, the type of fluid applied may be varied, for example, first applying a fluid with a stronger cooling effect, and then applying a fluid for wound healing. Moisture retention treatments may include steps that provide more (or less) moisture at specific points in the treatment. For example, a step that provides more moisture may involve providing more liquid than is removed and / or providing liquid more frequently than is removed. A step that provides less moisture may involve providing less liquid than is removed and / or providing liquid less frequently than is removed.

[0041] The computer 30 may identify a hydration treatment by any suitable method. The computer 30 may retrieve a hydration treatment from its memory 32. In certain embodiments, the computer 30 may identify a hydration treatment from a treatment pattern and customize the treatment to fit the pattern. For example, if there is a region in the pattern that requires more hydration (e.g., a higher density ablation shot), the treatment may include a step that provides more hydration to that region. In certain embodiments, the computer 30 may use machine learning or artificial intelligence to adjust the treatment. For example, the computer 30 may detect, via images from the camera 28, that a region requires more hydration and adjust the treatment to provide more fluid to that region.

[0042] In certain embodiments, the computer 30 performs a moisture retention procedure to adequately moisten the eye 22. The computer 30 may perform the procedure by any suitable method. For example, the computer 30 may remove any existing fluid from the tissue before each shot or before a series of shots. As another example, the computer 30 may add more fluid to the tissue at that location after each shot or after a series of shots.

[0043] Figure 2 shows examples of a liquid removal device 40 and a liquid dispenser 42 that may be used in the system 10 of Figure 1. In the example shown, the liquid removal device 40 includes a removal device pointer 46, and the liquid dispenser 42 includes a dispenser pointer 48.

[0044] The liquid removal device 40 may be any suitable device for removing the liquid present in place from the surface of the eye 22 to the outside by any suitable method. In a particular embodiment, the liquid removal device 40 removes the liquid by directing electromagnetic radiation and / or mechanical energy toward the liquid. For example, the liquid removal device 40 may include an ultrasonic emitter that generates ultrasonic waves to displace the liquid. In another example, the liquid removal device 40 may include an infrared emitter that generates infrared rays to dry the liquid. In yet another example, the liquid removal device 40 may include a laser source that generates a laser beam to dry the liquid (e.g., an excimer laser used for ablation or another laser). In yet another example, the liquid removal device 40 may include a device that generates jet air to dry the liquid (e.g., a tonometer).

[0045] The removal device pointer 46 directs the liquid removal device 40 to remove liquid at a specific location on the surface of the eye 22. In certain embodiments, the removal device pointer 46 may include an optical element or scanner that directs radiation and / or vibration to a specific location on the eye 22.

[0046] The liquid dispenser 42 may be any suitable device for applying liquid to the surface of the eye 22 by any suitable method. For example, the liquid dispenser 42 may include a sprayer for spraying the liquid onto the surface. As another example, the liquid dispenser 42 may include a cannula for narrowing the target of the liquid to a specific area of ​​the surface. The features of the liquid dispenser 42 may be tuned to change, for example, the direction, force, and / or range of the liquid application.

[0047] The dispenser pointer 48 directs the liquid dispenser 42 to dispense the liquid to a specific location on the surface of the eye 22. In certain embodiments, the dispenser pointer 48 may include a cylindrical component that directs the liquid to a specific location on the eye 22.

[0048] Figures 3 and 4 show an example of a method for managing appropriate hydration levels during ophthalmic surgery, which may be used with the system in Figure 1. The method begins in step 110, in which the computer 30 receives a treatment pattern to be used to treat the eye 22 during ophthalmic surgery. In step 112, the computer 30 identifies a hydration treatment. The computer 30 may recall a stored hydration treatment or identify a treatment from the treatment pattern.

[0049] The computer 30 instructs the liquid removal device 40, the laser device 15, and the liquid dispenser 42 to perform steps 114 and 120. In step 114, the liquid removal device 40 removes the liquid in place from the eye 22 to the outside according to the moisture retention procedure. In step 118, the laser device 15 cuts the eye tissue at that location according to the treatment pattern. In step 120, the liquid dispenser 42 dispenses more liquid at that location in the eye 22 according to the moisture retention procedure.

[0050] In step 122, the moisture retention procedure may be terminated according to the treatment pattern. If the procedure is not complete, the method returns to step 114, removes the fluid, and continues the procedure. Once the procedure is complete, the method proceeds to step 124 and terminates the procedure. In certain embodiments, in the final step of the moisture retention procedure, a large portion or all of the laser ablation area may be coated with fluid. The method is now complete.

[0051] Components of the systems and apparatus disclosed herein (such as computer 30) may include interfaces, logic, and / or memory, any of which may include computer hardware and / or software. Interfaces can receive inputs to and / or transmit outputs from components and are typically used to exchange information between software, hardware, peripherals, users, and combinations thereof. User interfaces (e.g., graphical user interfaces (GUIs)) are a type of interface that can be used for a user to interact with a computer. Examples of user interfaces include displays, touchscreens, keyboards, mice, gesture sensors, microphones, and speakers.

[0052] Logic can perform the actions of components. Logic may include one or more electronic devices that process data, for example, by executing instructions to produce an output from an input. Examples of such electronic devices include computers, processors, microprocessors (e.g., central processing units (CPUs)), and computer chips. Logic may also include computer software that encodes instructions that can be executed by the electronic devices to perform actions. Examples of computer software include computer programs, applications, and operating systems.

[0053] Memory may include tangible, computer-readable and / or computer-executable storage media capable of storing information. Examples of memory include computer memory (e.g., random-access memory (RAM) or read-only memory (ROM)), mass storage media (e.g., hard disks), removable storage media (e.g., compact discs (CDs) or digital video or multi-purpose discs (DVDs)), databases, network storage (e.g., servers), and / or other computer-readable media. Certain embodiments may involve memory encoded using computer software.

[0054] While this disclosure has described specific embodiments, modifications to the embodiments (e.g., changes, substitutions, additions, omissions, and / or other modifications) should be obvious to those skilled in the art. Therefore, modifications to the embodiments can be made without departing from the scope of the invention. For example, modifications can be made to the systems and apparatus disclosed herein. As will be obvious to those skilled in the art, the components of the systems and apparatus may be integrated or separated, and the operation of the systems and apparatus may be performed by more or fewer other components. Another example is the modification of the methods disclosed herein. As will be obvious to those skilled in the art, the methods may include more or fewer or other steps, and the steps may be performed in any suitable order.

[0055] To assist the Patent Office and readers in interpreting the claims, the applicant notes that, unless the words “means for” or “steps for” are expressly used in a particular claim, no claim or claim element is intended to evoke 35 U.S.C. § 112(f). The use of other terms in the claims (e.g., “mechanism,” “module,” “device,” “unit,” “component,” “element,” “member,” “apparatus,” “machine,” “system,” “processor,” or “controller”) is understood by the applicant to refer to structures known to those skilled in the art in the relevant art and is not intended to evoke 35 U.S.C. § 112(f).

Claims

1. In ophthalmic laser ablation systems, A laser device configured to direct laser radiation towards the eye as multiple shots to cut eye tissue according to a treatment pattern, A liquid removal device configured to remove the liquid present in the area from the surface of the eye tissue to the outside, It is a computer, Identify moisture retention measures, The liquid removal device is instructed to remove the liquid present in place from the surface of the tissue at the location of the eye to the outside, in accordance with the moisture retention procedure. The laser device is instructed to cut the tissue at the location of the eye according to the treatment pattern. A computer configured as follows, An ophthalmic laser ablation system including...

2. The ophthalmic laser ablation system according to claim 1, wherein the liquid removal device includes an ultrasonic emitter configured to generate a plurality of ultrasonic waves that displace the liquid.

3. The ophthalmic laser ablation system according to claim 1, wherein the liquid removal device includes an infrared emitter configured to generate a plurality of infrared rays for drying the liquid.

4. The ophthalmic laser ablation system according to claim 1, wherein the liquid removal device includes a laser source configured to generate a laser beam for drying the liquid.

5. The ophthalmic laser ablation system according to claim 1, wherein the liquid removal device includes a device configured to generate spray air for drying the liquid.

6. Identifying the aforementioned moisture retention treatment is The ophthalmic laser ablation system according to claim 1, comprising identifying the moisture retention treatment from the treatment pattern.

7. Removing the liquid present in place from the tissue at the location of the eye in accordance with the moisture retention procedure is, The ophthalmic laser ablation system according to claim 1, comprising removing the liquid before each of the plurality of shots.

8. Removing the liquid present in place from the tissue at the location of the eye in accordance with the moisture retention procedure is, The ophthalmic laser ablation system according to claim 1, comprising removing the liquid before a series of shots of the plurality of shots.

9. The present invention further includes a liquid dispenser configured to dispense liquid onto the surface of the aforementioned tissue, The aforementioned computer, The liquid dispenser is further configured to instruct the dispenser to apply liquid to the surface of the tissue at the location of the eye in accordance with the moisture retention procedure, The ophthalmic laser ablation system according to claim 1.

10. The ophthalmic laser ablation system according to claim 9, wherein the liquid dispenser includes a sprayer configured to spray liquid onto the surface of the tissue.

11. The ophthalmic laser ablation system according to claim 9, wherein the liquid dispenser includes a cannula configured to inject the liquid into the surface of the tissue.

12. Applying liquid to the surface of the tissue at the aforementioned location in the eye in accordance with the aforementioned moisture retention treatment is, The liquid is applied after each of the plurality of shots, The ophthalmic laser ablation system according to claim 9.

13. Applying liquid to the surface of the tissue at the aforementioned location in the eye in accordance with the aforementioned moisture retention treatment is, The liquid is applied after a series of shots of the plurality of shots, The ophthalmic laser ablation system according to claim 9.

14. Applying liquid to the surface of the tissue at the aforementioned location in the eye in accordance with the aforementioned moisture retention treatment is, This includes reapplying the removed liquid to the surface of the tissue at the location of the eye. The ophthalmic laser ablation system according to claim 9.

15. Applying liquid to the surface of the tissue at the aforementioned location in the eye in accordance with the aforementioned moisture retention treatment is, This includes providing a liquid that has a strong cooling effect. The ophthalmic laser ablation system according to claim 9.

16. Applying liquid to the surface of the tissue at the aforementioned location in the eye in accordance with the aforementioned moisture retention treatment is, Including the application of fluids for wound healing, The ophthalmic laser ablation system according to claim 9.

17. In the ophthalmic laser ablation method, The laser device directs the laser beam toward the eye as multiple shots that cut the eye tissue according to a treatment pattern, The liquid removal device removes the liquid present from the surface of the eye tissue to the outside, By computer, Identify moisture retention measures, The liquid removal device is instructed to remove the liquid present in place from the surface of the tissue at the location of the eye to the outside, in accordance with the moisture retention procedure. The laser device is instructed to cut the tissue at the location of the eye according to the treatment pattern. A method that includes performing the action.

18. Identifying the aforementioned moisture retention treatment is This includes identifying the moisture retention treatment from the treatment pattern. The method according to claim 17.

19. The liquid is applied to the surface of the tissue using a liquid dispenser, The computer instructs the liquid dispenser to apply liquid to the surface of the tissue at the location of the eye in accordance with the moisture retention procedure, Further including, The method according to claim 17.

20. Applying the liquid to the surface of the tissue at the location of the eye in accordance with the moisture retention treatment is, This includes reapplying the removed liquid to the surface of the tissue at the location of the eye. The method according to claim 19.

21. Applying the liquid to the surface of the tissue at the location of the eye in accordance with the moisture retention treatment is, By applying a liquid with a strong cooling effect, Applying fluids for wound healing, The method according to claim 19, including the method described in claim 19.

22. In ophthalmic laser ablation systems, A laser device configured to direct laser radiation towards the eye as multiple shots to cut eye tissue according to a treatment pattern, A liquid removal device configured to remove the liquid present in the area from the surface of the eye tissue to the outside, A liquid dispenser configured to dispense liquid onto the surface of the tissue, It is a computer, The moisture retention treatment is identified from the treatment pattern, The liquid removal device is commanded to remove the liquid present in place from the surface of the tissue at a certain location in the eye in accordance with the moisture retention procedure, and the liquid is removed before each shot or a series of shots of the plurality of shots. The laser device is instructed to cut the tissue at the location of the eye according to the treatment pattern, The liquid dispenser is instructed to dispense more liquid onto the surface of the tissue at the location of the eye in accordance with the moisture retention treatment, the liquid being dispensed after each shot or after a series of shots, and the dispensing of more liquid is By applying a liquid with a strong cooling effect, The removed liquid is then reapplied to the surface of the tissue at the location of the eye. Applying fluids for wound healing, including A computer configured as follows, An ophthalmic laser ablation system including...

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