Transparent skin patch and method for manufacturing the same

Abstract

The present invention provides a transparent skin patch that maintains adhesion and transparency even when worn for extended periods, and a method for manufacturing a transparent skin patch. [Solution] The transparent patch for skin may include a surface layer comprising a hydrogel mixture, a surface layer forming a surface, an intermediate layer provided in contact with one surface of the surface layer and formed by mixing a first mixture that provides ultraviolet blocking function with a second mixture comprising the hydrogel mixture, and a skin contact layer provided in contact with one surface of the intermediate layer and comprising the hydrogel mixture.

Description

Technical Field

[0001] The present invention relates to a transparent patch that adheres to the skin, and more specifically, to a transparent patch containing an ultraviolet blocking component and a hydrogel mixture for improving the skin condition, and a method for manufacturing the same.

Background Art

[0002] In the fields of skin care and medicine, skin-adhesive patches are positioned as important tools for improving and protecting the skin condition. Such skin-adhesive patches are developed for various applications such as drug delivery systems, beauty management, wound protection and treatment, and operate in a manner of directly adhering to the skin and transmitting components. In particular, it is widely used for skin beauty purposes such as ultraviolet blocking, wrinkle improvement, moisturizing, and acne treatment. In the medical field, it may also play a role in supporting wound recovery or transmitting specific drugs to the skin for a long time.

[0003] Another important function of skin-adhesive patches is to protect the skin from ultraviolet rays. Ultraviolet (UV) rays can cause problems such as skin aging, spots, and skin cancer, and ultraviolet blocking is essential. However, although conventional skin-adhesive patches have the function of transmitting ultraviolet blocking components to the skin, there is a problem that their performance and application functions are often unsatisfactory. For example, some products such as golf patches are conspicuous in skin color and have aesthetic problems, and due to the limit of adhesion, there is a risk of falling off in a wet environment or a situation with a lot of movement. As a result, consumers have come to prefer more transparent and better-adhering patches.

[0004] On the other hand, skin-adhesive patches having transparency provide transparency, but have problems such as the occurrence of wrinkles and the absence of a cooling effect. Skin-adhesive patches having transparency may impose a burden on the skin due to the adhesive force, may cause irritation to the skin during long-term wearing, lack the function of lowering the skin temperature during use or preventing skin troubles, and cannot provide sufficient satisfaction to consumers.

[0005] Furthermore, problems with conventional skin-adhering patches include the fact that the UV-blocking components may not be evenly distributed on the skin, or that the blocking effect may decrease over time. In addition, if the adhesion of the patch decreases due to the curves and movement of the skin, the UV-blocking effect will decrease, and the patch may easily fall off due to environmental factors such as sweat and water. As a result of these problems, the UV-blocking function may not be fully realized.

[0006] Furthermore, in the case of UV-blocking patches, transparency that makes them inconspicuous from the outside is a crucial factor. Consumers who prioritize aesthetics, in particular, want patches that are not noticeable when attached to the skin. However, conventional patches have difficulty meeting this requirement, and there is a need for technology that can effectively contain UV-blocking components while maintaining a transparent structure. [Prior art documents] [Patent Documents]

[0007] [Patent Document 1] Republic of Korea Patent Publication No. 10-2014-0081055 [Overview of the Initiative] [Problems that the invention aims to solve]

[0008] The problem that this invention aims to solve is the aforementioned problem, and it provides a transparent skin patch that can maintain adhesion and transparency even when worn for a long period of time.

[0009] The problems that this invention aims to solve are not limited to those mentioned above, and other problems not mentioned can be clearly understood by an ordinary person of the art from the following description. [Means for solving the problem]

[0010] Transparent skin patches according to various embodiments of the present invention for solving the aforementioned problems are disclosed. The transparent skin patch may comprise a surface layer comprising a hydrogel mixture, a surface layer forming a surface, an intermediate layer provided in contact with one surface of the surface layer and formed by mixing a first mixture that provides ultraviolet blocking functionality with a second mixture comprising the hydrogel mixture, and a skin contact layer provided in contact with one surface of the intermediate layer and comprising the hydrogel mixture.

[0011] In other embodiments, the hydrogel mixture comprises distilled water, acrylamide, a hydrophilic polymer, methylenebisacrylamide (MBA), and ammonium persulfate (APS), wherein the hydrophilic polymer is a water-absorbing polymeric substance that may include at least one of agarose, chitin, chitosan, gelatin, hyaluronic acid, carboxymethylcellulose (CMC), and polyvinyl alcohol (PVA).

[0012] In other embodiments, the distilled water is provided in an amount of 50 to 55 parts by weight per 100 parts by weight of the hydrogel mixture, the acrylamide is provided in an amount of 40 to 45 parts by weight per 100 parts by weight of the hydrogel mixture, the hydrophilic polymer is provided in an amount of 5 to 10 parts by weight per 100 parts by weight of the hydrogel mixture, the methylenebisacrylamide is provided in an amount of 0.025 to 0.030 parts by weight per 100 parts by weight of the hydrogel mixture, and the ammonium persulfate is provided in an amount of 0.125 to 0.130 parts by weight per 100 parts by weight of the hydrogel mixture.

[0013] In other embodiments, the first mixture comprises avonenzone, ethylhexyl salicylate, homosalate, and octocrylene, wherein the avonenzone is provided in an amount of 10 to 15 parts by weight per 100 parts by weight of the first mixture, the ethylhexyl salicylate is provided in an amount of 15 to 20 parts by weight per 100 parts by weight of the first mixture, the homosalate is provided in an amount of 35 to 40 parts by weight per 100 parts by weight of the first mixture, and the octocrylene is provided in an amount of 35 to 40 parts by weight per 100 parts by weight of the first mixture.

[0014] In other embodiments, the intermediate layer may be composed of the first mixture and the second mixture mixed in a ratio ranging from 20 parts by weight to 80 parts by weight to 30 parts by weight to 70 parts by weight, respectively.

[0015] In other embodiments, the intermediate layer may further comprise a zinc oxide (ZnO) and glycol-based solution.

[0016] In other embodiments, the zinc oxide is dispersed in the form of particles smaller than 100 nm in size, and the particles may be provided in the form of at least one of spherical, plate-like, rod-like, or irregular shapes.

[0017] A method for manufacturing a transparent patch for skin according to another embodiment of the present invention is disclosed. The method comprises the steps of generating a skin contact layer, generating an intermediate layer on one surface of the skin contact layer, and generating a surface layer on one surface of the intermediate layer, wherein the skin contact layer, the intermediate layer, and the surface layer are composed of a hydrogel mixture.

[0018] In other embodiments, the step of generating the intermediate layer may include the steps of generating a first mixture, generating an initial mixture by adding acrylamide, zinc oxide, and a hydrophilic polymer to distilled water, adding methylenebisacrylamide to the initial mixture and mixing, a mixing mixture step in which the first mixture is added to the initial mixture containing methylenebisacrylamide and mixed, adding ammonium persulfate to the mixing mixture and performing a mixing step, and generating a film-like intermediate layer by performing a film formation step based on the final mixture after mixing is complete and curing.

[0019] In other embodiments, the step of producing the first mixture may include the step of mixing avobenzone, ethylhexyl salicylate, homosalate, and octocrylene to produce a first initial mixture, and the step of adding a glycol-based solution to the first initial mixture to produce the first mixture.

[0020] Other specific details of the present invention are included in the detailed description and drawings. [Effects of the Invention]

[0021] In various embodiments of the present invention, all layers constituting the patch contain hydrogel components, which improves moisture retention, allowing the patch to adhere to the skin for extended periods and maintain adhesion even with the curves and movements of the skin. Furthermore, the transparent properties of the hydrogel improve the transparency of the patch, providing aesthetic satisfaction, and it can retain moisture even during prolonged use, minimizing skin irritation.

[0022] Furthermore, the transparent patch of the present invention is less irritating even when used for extended periods, minimizing skin problems while continuously maintaining its UV-blocking effect, thus simultaneously satisfying user convenience and safety.

[0023] The effects of the present invention are not limited to the effects mentioned above, and other effects not mentioned will be clearly understood by those skilled in the art from the following description.

Brief Description of Drawings

[0024] Various aspects are described with reference to the drawings, where like reference numerals are used throughout to refer to like components. In the following examples, for purposes of explanation, numerous specific details are presented to provide a thorough understanding of one or more aspects. However, it will be apparent that those aspects can be practiced without such specific details.

[0025] [Figure 1] FIG. 1 is an exemplary diagram for explaining the peeling phenomenon due to the mechanical properties between the film and the adhesion site.

[0026] [Figure 2] FIG. 2 is an exemplary diagram for explaining the adhesion force between the film composed of a hydrogel mixture according to an embodiment of the present invention and the skin.

[0027] [Figure 3] FIG. 3 is an exemplary diagram showing the actual attachment state of the transparent skin patch according to an embodiment of the present invention.

[0028] [Figure 4] FIG. 4 is an exemplary diagram illustratively showing a cross-section of the transparent skin patch according to an embodiment of the present invention.

[0029] [Figure 5] FIG. 5 is an exemplary diagram for explaining that the intermediate layer contains nanoparticles according to an embodiment of the present invention.

[0030] [Figure 6] FIG. 6 shows an exemplary flowchart of a method for manufacturing the transparent skin patch according to an embodiment of the present invention.

[0031] [Figure 7] Figure 7 is an illustrative diagram illustrating the adhesion strength test process and results according to one embodiment of the present invention.

[0032] [Figure 8] Figure 8 is an illustrative diagram illustrating the biocompatibility test process and results according to one embodiment of the present invention. [Modes for carrying out the invention]

[0033] Various embodiments and / or aspects are disclosed with reference to the drawings. In the following description, numerous specific details are disclosed for illustrative purposes to aid in the overall understanding of one or more embodiments. However, it will also be apparent to those ordinary skill in the art of the invention that these embodiments can be carried out without such specific details. The following description and accompanying drawings describe in detail specific exemplary embodiments of one or more embodiments. However, these embodiments are illustrative, and some may be used in various ways in the principles of various embodiments, and the description is intended to include all such embodiments and their equivalents. Specifically, the terms “embodiments,” “examples,” “aspects,” “exemplifications,” etc., as used herein, do not necessarily imply that any embodiment or design described is better or more advantageous than any other embodiment or design.

[0034] Hereafter, regardless of the reference numerals used in the drawings, identical or similar components will be given the same reference numeral, and redundant descriptions thereof will be omitted. Furthermore, when describing the embodiments disclosed herein, if it is determined that a specific description of the relevant prior art would obscure the gist of the embodiments disclosed herein, such detailed description will be omitted. In addition, the accompanying drawings are provided to facilitate understanding of the embodiments disclosed herein, and the accompanying drawings do not limit the technical ideas disclosed herein.

[0035] Although terms such as "first," "second," etc., are used to describe various elements and components, it goes without saying that these elements and components are not limited by these terms. These terms are used simply to distinguish one element or component from another. Therefore, it goes without saying that the first element or component referred to below may be the second element or component within the technical concept of the present invention.

[0036] Unless otherwise specified, all terms used herein (including technical and scientific terms) should be used in a sense that can be commonly understood by a person of ordinary skill in the art to which this invention pertains. Furthermore, terms defined in commonly used dictionaries should not be interpreted ideally or excessively unless otherwise explicitly defined.

[0037] Furthermore, the term "or" is intended to mean an implicational "or," not an exclusive "or." That is, unless otherwise specified or unclear from the context, "X uses A or B" is intended to mean one of the natural implicational substitutions. That is, if X uses A, or X uses B, or X uses both A and B, "X uses A or B" can apply to any of these cases. Also, the term "and / or" as used herein should be understood to refer to and include all possible combinations of one or more of the listed related items.

[0038] Furthermore, the terms “include” and / or “contain” should be understood to mean that such feature and / or component exists, but not to exclude the existence or addition of one or more other features, components and / or groups thereof. Also, where not specifically identified or where it is not contextually clear that the singular form is used, in this specification and claims, the singular form should generally be interpreted as meaning “one or more.”

[0039] When one component is described as being "linked" or "connected" to another component, it should be understood that it may be directly linked to or connected to the other component, but that other components may also be present in between. On the other hand, when one component is described as being "directly linked" or "directly connected" to another component, it should be understood that there are no other components in between.

[0040] When elements or layers are referred to as "on" or "on" another element or layer, this includes not only directly above the other element or layer, but also all cases where another layer or other element is interposed in between. On the other hand, when elements are referred to as "directly on" or "directly above," it indicates that there is no other element or layer interposed in between.

[0041] Spatially relative terms such as "below," "beneath," "lower," "above," and "upper" may be used to easily describe the correlation between one component and other components, as shown in the drawings. Spatially relative terms should be understood as terms that include different directions for elements in use or operation, in addition to the directions shown in the drawings.

[0042] The objectives and effects of the present invention, and the technical configurations for achieving them, will become clear by referring to the embodiments described in detail below, along with the accompanying drawings. When describing the present invention, if a specific description of a known function or configuration is deemed to obscure the gist of the invention, such detailed description will be omitted. Furthermore, the terms used below are defined in consideration of the functions of the present invention and may change depending on the intent or conventions of the user or operator.

[0043] However, the present invention is not limited to the embodiments disclosed below and may be embodied in various forms. These embodiments are provided merely to complete the invention and to fully inform those skilled in the art of the invention of the categories of disclosure, and the invention is defined only by the categories of claims. Therefore, the definition should be based on the content of the entire specification.

[0044] The transparent skin patch 1000 of the present invention may be used as a cosmetic and protective patch that adheres directly to the user's skin and performs functions such as UV protection, moisturizing, and skin protection. The transparent skin patch 1000 provides both transparency and excellent adhesion, is easy to use in daily life, and is effective in preventing skin damage caused by ultraviolet rays and improving skin condition.

[0045] According to one embodiment of the present invention, the transparent skin patch 1000 is composed of a hydrogel component having mechanical properties similar to those of skin, thereby achieving improved adhesion and reduced peeling.

[0046] Generally, when there is a large difference in mechanical properties between the film (or patch) and the adhesive site (e.g., skin), as shown in Figure 1(a), uneven stress is generated at the adhesive site, reducing the adhesive strength and easily causing delamination. Figure 1 is an illustrative diagram illustrating the delamination phenomenon caused by the mechanical properties between the film and the adhesive site.

[0047] More specifically, Figure 1(a) shows a situation where delamination occurs due to stress concentration between the film and the skin when there is a large difference in physical properties. The harder the film and the greater the difference in physical properties between it and the skin, the more stress concentrates at the adhesive site, which can make the patch more likely to fall off.

[0048] On the other hand, as shown in Figure 1(b), when the mechanical properties are similar, the stress distribution at the adhesive site becomes uniform, and the adhesion between the film and the skin is stably maintained. Such mechanical properties can be achieved by using skin-like materials such as hydrogels, which is one of the important technical features of the transparent skin patch 1000 of the present invention.

[0049] When the hydrogel mixture of the present invention is formed in the form of a film (or patch), i.e., a hydrogel film 10, the hydrogel film 10 adheres strongly to the user's skin and flexibly conforms to the curves of the skin, as shown in Figure 2. Figure 2 is an illustrative diagram illustrating the adhesive force between a film containing the hydrogel mixture according to one embodiment of the present invention and the skin. Due to the high water content and flexibility inherent to hydrogels, the hydrogel film 10 can provide a comfortable fit while adhering closely to the skin and can maintain a stable contact area with the skin for extended periods. Hydrogels commonly used inevitably experience rapid water loss at room temperature, which may somewhat reduce their mechanical properties and adhesive properties. In the case of the hydrogel mixture of the present invention, a solvent with high boiling and freezing points and a negative charge function opposite to the positively charged hydrogen of water is utilized, allowing each solvent molecule to retain water for extended periods through hydrogen bonding and providing an antifreeze function.

[0050] Furthermore, the hydrogel film of the present invention can embody mechanical properties similar to those of the human body, particularly facial skin, through the optimization of functional materials. To achieve this, high mechanical properties are provided by adjusting the composition ratio of the hydrogel material to form a double network structure through the interaction and entanglement of polymer chains. Such a double network hydrogel can mimic the elasticity and flexibility of skin, maintaining stable adhesion without putting strain on the skin even when worn for extended periods.

[0051] In other words, the present invention provides a hydrogel patch having physical properties similar to skin through an optimized composition ratio and reaction mechanism of the material, thereby enabling stable adhesion to the user's skin for extended periods and minimizing the reduction in adhesive strength and peeling phenomena.

[0052] Furthermore, referring to Figure 3, the transparent skin patch 1000 of the present invention provides excellent transparency and remains virtually invisible from the outside even when attached to the skin. Figure 3 is an illustrative diagram showing the actual attachment state of a transparent skin patch according to one embodiment of the present invention. As shown in Figure 3, the transparent skin patch 1000 of the present invention appears to be integrated with the skin, which can be achieved by the high transparency of the hydrogel mixture component of the present invention.

[0053] Conventional patch products are easily noticeable when applied to the skin, which can be an aesthetic burden for the user. However, the transparent skin patch 1000 of the present invention solves this problem by using a hydrogel mixture with excellent transparency, and can perform UV blocking and skin protection functions while remaining transparent even after being applied to the skin.

[0054] In the examples, the transparent skin patch 1000 of the present invention appears almost identical in color to the skin, minimizing light scattering and making it difficult to perceive the patch's presence from the outside. As a result, the patch can be used in daily life without aesthetic burden, maintains its transparency even with prolonged wear, and offers the advantages of enhancing user comfort and aesthetic satisfaction.

[0055] The composition of each layer included in the transparent skin patch of the present invention, its effects, and the manufacturing method will be explained in more detail below with reference to Figures 4 to 6.

[0056] Figure 4 is an illustrative diagram showing a cross-section of a transparent skin patch according to one embodiment of the present invention.

[0057] As shown in Figure 4, the transparent skin patch 1000 may include a surface layer 100, an intermediate layer 200, and a skin contact layer 300.

[0058] Specifically, the transparent skin patch 1000 is composed of a hydrogel mixture and may include a surface layer 100 that forms a surface.

[0059] According to the example, the surface layer 100 plays a role in suppressing the evaporation of moisture and preventing the lipid-soluble UV-blocking component contained in the intermediate layer 200 from seeping outside the patch. The moisture content of the hydrogel is an important factor in ensuring that the patch adheres to the skin for a long time and does not dry out the skin, and the surface layer 100 functions as a first line of defense to protect it.

[0060] Furthermore, by preventing the UV-blocking components contained in the intermediate layer 200 from flowing out through the surface, the UV-blocking components remain on the skin for a long period of time, providing a sustained protective effect. The surface layer 100 maximizes the functionality of the patch through moisture retention and protection of the UV-blocking components, providing a stable skin protective effect for a long period of time.

[0061] Furthermore, the surface layer 100 maintains transparency while being highly durable, and can protect the patch from external irritation and contamination of the skin. This extends the overall lifespan of the patch and minimizes the loss of moisture evaporation and UV-blocking components even with prolonged use.

[0062] In one embodiment, the surface layer 100 is constructed based on the unique hydrogel mixture of the present invention, which maintains a high moisture content and a transparent appearance, and can adhere naturally to the skin to provide a comfortable wearing experience. Specifically, the hydrogel mixture of the present invention is made with specific components and precisely adjusted proportions to maximize the suppression of moisture evaporation and the protection of UV-blocking components. This optimized composition ratio simultaneously improves the flexibility and durability of the hydrogel, allowing the patch to provide comfortable and stable adhesion even when it is in contact with the skin for extended periods.

[0063] For example, components such as monomers for moisture-retaining polymers, crosslinking agents, and curing agents are mixed in appropriate proportions to ensure the structural stability of the hydrogel and to protect the lipid-soluble UV-blocking agent from seeping from the intermediate layer to the surface. As a result, the transparent skin patch of the present invention provides excellent performance and durability simultaneously, maintaining effective UV blocking and moisture protection functions even after prolonged use.

[0064] The hydrogel mixture of the present invention may comprise distilled water, acrylamide, a hydrophilic polymer, methylenebiscrylamide (MBA), and ammonium persulfate (APS).

[0065] In the examples, distilled water acts as the main solvent for the hydrogel, dissolving the polymer components and promoting uniform mixing. The distilled water forms the basis for maintaining the water content of the hydrogel, and together with the added water evaporation inhibitor, it allows the hydrogel to maintain its flexibility and adhesion.

[0066] Acrylamide is the main monomer of hydrogels and can form the structural basis of them. Acrylamide forms polymer chains through polymerization, a process that determines the mechanical strength and flexibility of the hydrogel. In some cases, the physical properties of a hydrogel can change depending on the acrylamide content.

[0067] Hydrophilic polymers may be polymeric substances that have hydrophilic properties and absorb moisture. Hydrophilic polymers play a role in improving moisture absorption and retention capabilities. For example, hydrophilic polymers may include at least one of agarose, chitin, chitosan, gelatin, hyaluronic acid, carboxymethylcellulose (CMC), and polyvinyl alcohol (PVA). Hydrophilic polymers contribute to hydrogels retaining moisture for extended periods and minimizing skin irritation.

[0068] Methylenebisacrylamide acts as a cross-linker, forming bonds between polymer chains within the hydrogel. These cross-links maintain the structural stability of the hydrogel and increase its mechanical strength, providing robust resistance to external impacts and deformation. In one example, increasing the amount of cross-linker increases the hardness of the hydrogel, but if too much is added, the flexibility of the hydrogel may decrease. Therefore, it is extremely important to adjust the amount of cross-linker to an appropriate level.

[0069] Ammonium persulfate acts as a radical initiator, initiating the polymerization of acrylamide. It accelerates the chemical reaction, supporting the rapid and stable formation of the hydrogel. Furthermore, ammonium persulfate plays a crucial role in the curing process of the hydrogel, contributing to the stable maintenance of its morphology and structure.

[0070] The hydrogel mixture of the present invention is designed with an optimized and original recipe, which maximizes various properties such as skin adhesion, flexibility, moisture retention, and transparency.

[0071] In the examples, distilled water is provided in an amount of 50 to 55 parts by weight per 100 parts by weight of the hydrogel mixture, acting as the main solvent for the hydrogel and forming an important base for uniform mixing of the components and suppressing evaporation that retains moisture content. The optimized ratio of distilled water helps the film adhere to the skin for a long period of time while maintaining the moisture content of the hydrogel.

[0072] Acrylamide is provided in an amount of 40 to 45 parts by weight per 100 parts by weight of the hydrogel mixture, contributing as a monomer to form the structural foundation of the hydrogel. The proportion of acrylamide provides a good balance of strength and flexibility in the hydrogel, resulting in a comfortable fit when applied to the skin and durability that can withstand external impacts.

[0073] Hydrophilic polymers are provided in an amount of 5 to 10 parts by weight per 100 parts by weight of the hydrogel mixture. They maximize the water absorption capacity of the hydrogel, minimize skin irritation even during prolonged use, and keep the skin moist. Among these hydrophilic polymers, agarose, chitin, chitosan, and gelatin maximize compatibility with the skin while retaining moisture, thereby improving the skin-protective effect of the hydrogel.

[0074] Methylenebisacrylamide is provided in an amount of 0.025 to 0.030 parts by weight per 100 parts by weight of the hydrogel mixture, acting as a crosslinking agent to form bonds between the polymer chains of the hydrogel. These proportions may be optimized to maintain the structural stability of the hydrogel without losing flexibility. While excessive use of crosslinking agents can reduce flexibility, this invention ensures both flexibility and strength through precise adjustments.

[0075] Ammonium persulfate is provided in an amount of 0.125 to 0.130 parts by weight per 100 parts by weight of the hydrogel mixture, acting as a radical initiator to promote the polymerization reaction of the hydrogel. These proportions allow the hydrogel to cure rapidly and stably, maintaining its form while remaining stable even when applied to the skin.

[0076] The optimized component ratio of the hydrogel mixture described above gives the hydrogel of the present invention properties that differentiate it from conventional products, providing performance as an innovative skin patch that maximizes moisture retention and skin affinity while maintaining transparency and adhesion.

[0077] Furthermore, in the embodiment, the transparent skin patch 1000 may include an intermediate layer 200 provided in contact with one surface of the surface layer 100. The intermediate layer 200 may be provided between the surface layer 100 and the skin contact layer 300. The intermediate layer 200 is located beneath the surface layer 100 in direct contact with it and also adheres closely to the skin contact layer 300, acting as a layer that provides the core function of the patch. The intermediate layer 200 is located in the center of the patch and provides UV protection and moisture retention functions while complementing the external protection function of the surface layer 100 and the skin adhesion function of the skin contact layer 300.

[0078] The intermediate layer 200 may be formed by mixing a first mixture that provides UV blocking functionality with a second mixture containing a hydrogel mixture. More specifically, the intermediate layer 200 may contain the hydrogel mixture of the present invention as is, while being uniformly mixed with the first mixture containing a lipid-soluble UV blocker to provide UV blocking performance, as well as skin adhesion and moisture retention. In the examples, the first mixture may contain at least one UV blocking component such as avobenzone, ethylhexyl salicylate, homosalate, and octocrylene, and such UV blocking component exhibits a sustained UV blocking effect while being retained on the skin for a long time in the intermediate layer.

[0079] In specific examples, the intermediate layer 200 may be formed by uniformly mixing a first mixture containing UV-blocking components such as avobenzone, ethylhexyl salicylate, homosalate, and octocrylene with a hydrogel mixture. Each UV-blocking component is present in a specific proportion within the first mixture and is mixed in precisely adjusted proportions to optimize UV-blocking performance.

[0080] The intermediate layer 200 of the present invention is designed to effectively block both UV-A and UV-B rays. Avobenzone contained in the first mixture plays a role in effectively blocking ultraviolet rays in the UV-A (320-400 nm) region, while ethylhexyl salicylate, homosalate, and octocrylene are components that block ultraviolet rays in the UV-B (280-320 nm) region, and each component exerts a synergistic effect to block both UV-A and UV-B rays simultaneously.

[0081] The first mixture containing such UV-blocking components forms an intermediate layer with the hydrogel mixture of the present invention, thereby maximizing UV-blocking performance while maintaining skin adhesion and moisture retention. UV-A penetrates deep into the skin and can cause wrinkles and skin aging, while UV-B is the main cause of sunburn on the skin's surface. The patch of the present invention plays a role in effectively preventing skin damage by blocking both UV-A and UV-B.

[0082] More specifically, avobenzone is provided in an amount of 10 to 15 parts by weight per 100 parts by weight of the first mixture, and this is a very effective component for blocking UV-A. Although avobenzone is sensitive to ultraviolet light and its effectiveness may decrease when exposed to ultraviolet light, when mixed with the hydrogel mixture together with the other UV-blocking agents of the present invention, it can provide long-lasting UV-blocking effects while maintaining stability.

[0083] Ethylhexyl salicylate is provided in an amount of 15 to 20 parts by weight per 100 parts by weight of the first mixture and is an effective ingredient for blocking ultraviolet rays, protecting the skin from ultraviolet rays and increasing the stability of avobenzone.

[0084] Homosalate is provided in an amount of 35 to 40 parts by weight per 100 parts by weight of the first mixture, and plays a role in further enhancing the UV-B blocking performance. Homosalate works in synergy with other UV-blocking agents to provide long-lasting protection against skin damage caused by UV-B.

[0085] Octocrylene is provided in an amount of 35 to 40 parts by weight per 100 parts by weight of the first mixture. In addition to its UV-blocking function, it plays a role in stabilizing UV-blocking agents that may be damaged by UV light. When mixed with avobenzone, it greatly contributes to further enhancing UV resistance and maintaining UV-blocking performance.

[0086] When the first mixture containing such UV-blocking components is mixed with the original hydrogel mixture of the present invention, the intermediate layer 200 performs a dual function, maximizing the UV-blocking function while also providing skin adhesion and moisture retention. The hydrogel mixture supports the stable delivery of the UV-blocking components to the skin, while simultaneously providing a comfortable wearing experience even when the patch is in contact with the skin for extended periods.

[0087] Therefore, the intermediate layer 200 combines an optimized ratio of UV-blocking components with the flexibility and moisture-retaining properties of the hydrogel, allowing the patch to effectively perform UV-blocking functions for a long period of time while naturally adhering to the skin and retaining moisture.

[0088] According to one embodiment of the present invention, the intermediate layer 200 is characterized in that the first mixture and the second mixture are mixed in a ratio ranging from 20 parts by weight to 80 parts by weight to 30 parts by weight to 70 parts by weight, respectively.

[0089] For example, if the first and second mixtures are not mixed in the appropriate proportions according to one embodiment of the present invention, the balance between UV blocking performance and moisture retention may be disrupted. For instance, if the proportion of the UV blocking component is excessively high, the flexibility and adhesion of the hydrogel may decrease, which can prevent the patch from adhering stably to the skin and increase the likelihood of it falling off. Conversely, if the proportion of the hydrogel mixture is excessively high, the UV blocking component may not be distributed at a sufficient concentration, thus reducing UV blocking performance. Such imbalances in proportions can reduce the performance of the patch, so it is important to maintain an appropriate ratio between the first and second mixtures.

[0090] This combination of proportions optimizes the balance between the UV-blocking component and the hydrogel mixture, maximizing both UV-blocking performance and skin adhesion simultaneously. Specifically, the first mixture consists of lipid-soluble UV-blocking components to provide UV protection, while the second mixture, the hydrogel mixture, plays a role in minimizing irritation by adhering to the skin for extended periods due to its moisture-retaining and flexible properties. The proportion range of these two mixtures is designed so that the UV-blocking component is effectively delivered to the skin while the high water content of the hydrogel reduces skin irritation and maintains moisturizing effects.

[0091] Furthermore, this ratio setting ensures that the patch adheres stably to the skin even when worn for extended periods, and that the UV-blocking components are uniformly dispersed within the hydrogel layer without leaching out, providing sustained protection from ultraviolet rays.

[0092] According to embodiments of the present invention, the intermediate layer 200 may further comprise zinc oxide (ZnO) and a glycol-based solution.

[0093] In the embodiment, zinc oxide is dispersed in nanoparticle form to maximize its UV blocking performance, which allows it to effectively absorb and reflect ultraviolet light. Figure 5 is an illustrative diagram illustrating the inclusion of nanoparticle-form zinc oxide in the intermediate layer according to one embodiment of the present invention. As shown in Figure 5, zinc oxide 210 is dispersed in nanoparticle form having a nano (e.g., less than 100 nm) size, playing a role in blocking ultraviolet light (UV-A and UV-B) over a wide area. Nano-sized zinc oxide particles physically reflect or scatter ultraviolet light, increasing the length through which it passes through the layer, and as a result, increase the absorption of ultraviolet light by the UV blocker, effectively reducing the amount of ultraviolet light that reaches the skin. Because the nanometer-level particles have a high surface area, the UV blocking performance can be further improved, maximizing the UV blocking function while maintaining the transparency of the patch.

[0094] In the examples, the particles may be provided in the form of at least one of spherical, plate-like, rod-like, and irregular shapes, each of which affects the UV blocking performance of zinc oxide. For example, spherical particles have the property of scattering light uniformly, while rod-like particles scatter light in a specific direction, enabling more efficient UV blocking. Such combinations of nanoparticle shapes allow the patch to adhere naturally to the skin and maintain a transparent appearance while blocking UV rays.

[0095] According to one embodiment, the glycol-based solution plays an important role in uniformly mixing zinc oxide and UV-blocking components with the hydrogel. The glycol solution suppresses water evaporation and supports the uniform distribution of UV-blocking components on the skin. Furthermore, the glycol-based solution improves the water-retention capacity of the hydrogel, allowing the patch to adhere to the skin for extended periods while keeping the skin moist.

[0096] As a specific example, glycol-based solutions may include, but are not limited to, triethylene glycol, polyethylene glycol (PEG), and diethylene glycol. In addition to the glycol substances mentioned above, various glycol-based substances having polyglycol, tetramolecular, or bimolecular structures may be used. Each of these substances can enhance moisture retention and effectively bind the UV-blocking component with the hydrogel, further improving the transparency, adhesion, and UV-blocking performance of the patch.

[0097] Glycol-based solutions play a role in capturing water, improving the hydrogel's moisture retention capacity and helping to prevent skin dryness even when the patch is in contact with the skin for extended periods. Furthermore, glycol-based solutions function similarly to soap, playing a crucial role in binding the lipid-soluble UV-blocking components with the hydrogel mixture. This allows the lipid-soluble UV-blocking agent, UV oil, to be uniformly mixed with the hydrogel mixture to form an intermediate layer 200, supporting the uniform delivery of the UV-blocking components to the skin.

[0098] Furthermore, the examples may also include a skin contact layer 300 that is in contact with one surface of the intermediate layer 200 and is composed of a hydrogel mixture.

[0099] The skin contact layer 300 contacts one surface of the intermediate layer 200 and may be composed of the hydrogel mixture of the present invention. Due to the flexibility and moisture-retaining properties of the hydrogel, the skin contact layer provides a comfortable wearing experience while adhering closely to the skin for extended periods, minimizing skin irritation.

[0100] Furthermore, the skin contact layer may also contain drug delivery components, thereby providing not only skin protection but also skin health improvement functions. For example, the skin contact layer 300 may contain components such as collagen, panthenol, hyaluronic acid, and vitamin C, which may provide increased skin elasticity, moisturizing, wrinkle reduction, and whitening effects.

[0101] For example, collagen enhances skin elasticity, panthenol promotes skin regeneration and hydration, hyaluronic acid retains moisture in the skin, and vitamin C contributes to skin whitening and wrinkle improvement through its antioxidant effects.

[0102] In addition to the aforementioned ingredients, the formula may also contain ingredients that provide soothing and anti-inflammatory effects, such as aloe vera extract and green tea extract, as well as anti-aging ingredients such as retinol and niacinamide. Antibacterial and wound-healing ingredients such as tea tree oil and salicylic acid may also be added, and various functional ingredients such as antioxidants, whitening agents, and moisturizers may be included as needed.

[0103] Therefore, the skin contact layer 300 of the present invention provides skin adhesion and moisture retention based on the hydrogel mixture, and can also perform functions such as effective nutrient delivery, elasticity improvement, moisturizing, and soothing to the skin as a drug delivery system.

[0104] As described above, the transparent skin patch 1000 of the present invention effectively blocks ultraviolet rays through its intermediate layer 200, which acts as an ultraviolet blocking layer, thereby protecting the skin from ultraviolet radiation. In particular, the surface layer 100 prevents the lipid-soluble ultraviolet blocking components contained in the intermediate layer 200 from seeping out, and supports the ultraviolet blocking components to act stably on the skin for a long period of time. Such a structure ensures the sustainability of the ultraviolet blocking performance and further improves the functionality of the patch.

[0105] Furthermore, the transparent skin patch 1000 contains the hydrogel mixture of the present invention in all layers, ensuring moisture retention, excellent adhesion, and high transparency. Due to the properties of the hydrogel, the patch adheres naturally to the skin, retains moisture even with prolonged use, and minimizes skin irritation. As a result, the transparent skin patch 1000 provides a comfortable wearing experience while maintaining stable adhesion over a long period of time.

[0106] Furthermore, the skin contact layer 300 can further enhance drug delivery, effectively delivering functional ingredients such as collagen, panthenol, and hyaluronic acid to the skin. This can lead to various skin improvement effects, including increased skin elasticity, moisturizing effects, and skin soothing.

[0107] In other words, the transparent skin patch 1000 of the present invention is a highly functional multilayer patch that ensures UV protection, moisture retention, adhesion, and transparency, while also providing a skin improvement function through drug delivery, thus offering excellent effects in skin protection and management.

[0108] Figure 6 shows an exemplary flowchart of a method for manufacturing a transparent skin patch according to one embodiment of the present invention. The steps shown in Figure 6 may be ordered as needed, and at least one or more steps may be omitted or added. In other words, the following steps are merely one embodiment of the present invention, and the scope of the present invention is not limited thereto.

[0109] According to one embodiment of the present invention, a method for manufacturing a transparent patch for skin may include step S100 of generating a skin contact layer.

[0110] More specifically, the skin contact layer 300 may be produced using a hydrogel mixture, in which the hydrogel components are uniformly mixed and formed into a film.

[0111] To create the skin contact layer 300, first, a hydrogel mixture containing distilled water, acrylamide, a hydrophilic polymer, methylenebisacrylamide, and ammonium persulfate is prepared. The hydrogel mixture allows the hydrogel to adhere to the skin while forming the basic structure of the patch. To ensure uniformity of the hydrogel mixture, a heating and mixing process is carried out at an appropriate temperature, during which a cross-linking reaction occurs, optimizing the mechanical strength and flexibility of the hydrogel.

[0112] Subsequently, the skin contact layer 300 is cast or molded into a film to form a layer with the desired thickness and structure. In this step, the film is controlled to maintain its moisture content, and drug delivery components may be added. The drug delivery components are slowly absorbed through the skin together with the hydrogel to provide a skin improvement effect.

[0113] Therefore, the skin contact layer may be manufactured with a structure based on hydrogel that has skin adhesion, moisture retention, and drug delivery functions.

[0114] According to one embodiment of the present invention, a method for manufacturing a transparent patch for skin may include step S200 of generating an intermediate layer on one surface of the skin contact layer 300.

[0115] First, the step of generating the intermediate layer may include the step of generating a first mixture, where the first mixture can mean a mixture containing an ultraviolet-blocking component that performs the ultraviolet-blocking function in the intermediate layer.

[0116] In specific examples, the step of producing the first mixture may include the step of mixing avobenzone, ethylhexyl salicylate, homosalate, and octocrylene to produce a first initial mixture, and the step of adding a glycol-based solution to the first initial mixture to produce the first mixture. Alternatively, the step of producing the initial mixture may include the step of adding zinc oxide to the initial mixture.

[0117] More specifically, the step of preparing the first mixture includes the following process:

[0118] First, avonenzone, ethylhexyl salicylate, homosalate, and octocrylene are mixed to create the first initial mixture. These UV-blocking components each play a role in blocking UV-A and UV-B rays, providing broad-spectrum UV protection to the skin.

[0119] Subsequently, a glycol-based solution is added to the first initial mixture to complete the first mixture. The glycol-based solution plays an important role in enabling uniform bonding between the UV-blocking component and the hydrogel, suppressing water evaporation, and supporting the long-term retention of the UV-blocking component on the skin. The resulting first mixture is then properly mixed with the hydrogel mixture in the following process, further improving the functionality and stability of the intermediate layer.

[0120] In specific examples, the step of generating the intermediate layer may include the steps of: generating an initial mixture by adding acrylamide, zinc oxide, and a hydrophilic polymer to distilled water; adding methylenebisacrylamide to the initial mixture and mixing; adding the first mixture to the initial mixture containing methylenebisacrylamide and mixing; adding ammonium persulfate to the mixing mixture and performing a mixing process; and performing a film formation process based on the final mixture after mixing to generate a film-like intermediate layer and then curing it.

[0121] To explain in more detail, the step of generating the intermediate layer may include the following process:

[0122] First, an initial mixture is prepared by adding acrylamide, a hydrophilic polymer (e.g., agarose), and zinc oxide to distilled water and mixing, then dissolving the mixture on a 90°C hotplate. In this step, the polymeric substance that forms the basis of the hydrogel dissolves, and the zinc oxide acts as a UV-blocking component. At this time, the size of the zinc oxide particles is set to 100 nm or less, which improves UV-blocking performance while maintaining the transparency of the patch.

[0123] Next, the mixed solution (i.e., the initial mixture or containment layer, aqueous phase) is agitated in a high-frequency processor for approximately 10 seconds to further homogenize the mixture. Then, methylenebisacrylamide (MBA) is added to the initial mixture and stirred. Methylenebisacrylamide acts as a crosslinking agent and plays a role in forming the structural strength of the hydrogel.

[0124] Next, the UV-blocking component of the organic phase, i.e., the first mixture, is added to the initial mixture. After mixing with a Thinky mixer for approximately 20 to 40 seconds, the mixing process is carried out using a shear mixer. At this point, both phases are uniformly mixed, and the UV-blocking component is uniformly distributed within the hydrogel.

[0125] Finally, after injecting ammonium persulfate (APS), the mixture is mixed again to create a film-like intermediate layer. For example, a stable and uniform film can be completed through a mixing process to quickly and uniformly mix the components after APS injection, a casting process to form the film, and a heat treatment process to cure it. Ammonium persulfate acts as a radical initiator, promoting the formation of polymer chains and supporting the rapid curing of the hydrogel. The prepared patch is then cured in a 70°C oven for 40 minutes to 1 hour to complete the process. In this process, the content of each component and the processing conditions are crucial factors in determining the final properties of the hydrogel, thereby producing an intermediate layer with optimized transparency, UV blocking performance, adhesion, and moisture retention.

[0126] According to one embodiment of the present invention, a method for manufacturing a transparent patch for skin may include step S300 of generating a surface layer 100 on one surface of the intermediate layer 200.

[0127] In the example, the surface layer 100 prevents the lipid-soluble UV-blocking component contained in the intermediate layer 200 from seeping out and suppresses moisture evaporation. The process of producing the surface layer 100 includes a step of uniformly applying the hydrogel mixture and may include a film-forming step that allows the hydrogel to maintain its transparency and adhesion. The resulting surface layer 100 combines with the intermediate layer 200 to maintain a transparent appearance while providing stability that allows it to adhere to the skin for a long time.

[0128] Furthermore, the surface layer 100 can optimize the physical properties of the hydrogel through a curing process, maximizing its moisture retention and durability. The formation process of the surface layer 100 may include temperature control to control mechanical properties and a curing step for a specific period of time.

[0129] The transparent skin patch 1000 of the present invention may be manufactured through the process steps described above. The manufactured transparent skin patch 1000 can adhere to the skin for a long time and provides high moisture retention and excellent transparency. In addition, the UV-blocking component contained in the middle layer of the patch protects the skin from ultraviolet rays for a long time, and the surface layer prevents the UV-blocking component from seeping out, thereby enhancing the persistence of the UV-blocking effect. Furthermore, the skin contact layer is composed of a skin-friendly hydrogel mixture, minimizing skin irritation, and may contain various drug delivery components as needed, simultaneously providing skin improvement effects.

[0130] Whether the transparent skin patch 1000 of the present invention exhibits UV blocking effect, skin adhesion, and moisture retention effect can be confirmed through the following experimental examples.

[0131] Experimental Example 1: Adhesion Test This experiment was conducted to confirm the adhesive strength of patches produced through the hydrogel mixture of the present invention to the skin. This allowed us to evaluate how stably a hydrogel material with a Young's modulus similar to that of skin maintains its adhesive strength on the surface of real skin.

[0132] The materials used in this experiment included a patch to which the hydrogel material of the present invention was applied, and pig skin, which has physical properties similar to human skin. The adhesive strength of the hydrogel patch of the present invention was evaluated using pig skin under conditions similar to those of human skin. Test equipment such as an adhesion tester, strain gauge, and high-resolution microscope were used to measure the adhesive strength.

[0133] First, after cleaning the surface of the pig's skin, a transparent patch coated with the hydrogel material of the present invention was attached to the surface of the pig's skin. After applying light pressure to secure the hydrogel patch to ensure complete adhesion to the skin surface, an adhesion test was performed. To evaluate the adhesive strength of the hydrogel patch, the stress (kPa) was measured based on the strain (%). The results showed that even with a strain close to 200% in the strain test, the hydrogel patch adhered strongly to the pig's skin, and the adhesive strength did not decrease significantly.

[0134] Strain (%) refers to the strain rate and indicates how much the hydrogel patch can stretch. In other words, it is the percentage of how much the patch stretches while attached to the skin. Stress (kPa) indicates the degree to which the hydrogel patch resists pressure or force applied while attached to the skin and is an important indicator for evaluating adhesion strength.

[0135] As shown in the graph in Figure 7, stress increases with increasing strain, but even at strains close to 200%, the adhesive strength (stress) of the hydrogel patch did not decrease significantly. This indicates that the hydrogel patch maintains its adhesive strength stably even when the skin deforms, i.e., when the skin stretches or moves. From this, we can conclude that the hydrogel patch can maintain stable adhesive strength even when used for a long time in close contact with the skin. In other words, it means that the hydrogel patch maintains strong adhesive strength even with skin movement and stretching.

[0136] Furthermore, adhesive strength tests recorded a shear stress of 36 kPa, indicating that the hydrogel patch maintains strong adhesion to the skin. This strong adhesion is confirmed to be maintained for a long period of time due to the water-retaining and flexible properties of the hydrogel material.

[0137] Finally, microscopic observation of the close bond between the pig skin and the hydrogel patch confirmed the formation of strong and effective hydrogen bonds between the hydrogel patch and the pig skin, resulting in strong adhesion to the skin surface. This type of bonding structure significantly improves the adhesive performance of the hydrogel. As a result, this experiment demonstrated that the hydrogel patch of the present invention exhibits strong adhesion under conditions similar to those of skin and maintains a stable adhesion even during prolonged use. Furthermore, the high water content and flexibility of the hydrogel material resulted in excellent adhesive performance in strain tests.

[0138] Experimental Example 2: Biocompatibility Test Biocompatibility testing was conducted through in vitro cell experiments to confirm whether the hydrogel material of the present invention functions appropriately in a biological environment when it is in prolonged contact with the skin. The NIH 3T3 cell line was used in the experiments, and these cells are fibroblasts of the skin that play an important role in skin regeneration and healing.

[0139] First, in the experimental preparation process, the hydrogel of the present invention was placed as a sample on a culture dish containing NIH 3T3 cells, as shown in Figure 8. The hydrogel was attached to the culture dish so as to be in direct contact with the cells, and the experiment was conducted in a manner that evaluated the interaction between the cells and the hydrogel. High-resolution microscopy and fluorescence staining were used to confirm the presence or absence of cell growth and deformation during the experiment. Cell viability and morphological changes were visually confirmed through fluorescence staining, and it was evaluated whether the hydrogel material induced toxicity in the cells.

[0140] As shown in Figure 8, the experimental results demonstrated that the hydrogel material of the present invention did not induce cytotoxicity, and NIH 3T3 cells survived and proliferated normally. In particular, the hydrogel material maintained its non-swelling properties despite prolonged contact with cells and showed almost no structural deformation, demonstrating that it does not excessively absorb moisture or deform even when used for extended periods in the body environment. Furthermore, it was confirmed that cells differentiated and grew normally on the surface of the hydrogel.

[0141] This confirms that the hydrogel material of the present invention does not cause problems even when in contact with the skin for a long period of time and acts harmlessly on the human body.

[0142] Experiment Example 3: Evaluation of skin moisturizing and adhesion properties This study was conducted to evaluate the moisturizing effect, adhesion, UV blocking effect, and other skin-improving effects of the transparent skin patch of the present invention when applied to actual human skin. The experiment involved 20 adult women aged 30 to 60 years (average age 50.05 ± 6.08 years). All participants met the research participation criteria and were selected for their normal skin condition. The experiment was conducted on the face (around the eyes) and forearm (upper arm), and the subjects applied the transparent skin patch of the present invention once a day.

[0143] First, in the facial experiment, the patch was applied to the area from the cheekbone around the eye to the temple after washing and drying the face, and was left on for 4 hours before being removed. Additionally, to evaluate the skin temperature reduction (cooling) effect, the test product was applied to both sides of the face, using the nose as a reference point, and removed after 15 minutes. In the forearm experiment, a 4cm x 4cm patch was applied, left on for 4 hours, and then removed.

[0144] Skin moisturizing ability was evaluated by comparing skin moisture content before and after patch application. The 24-hour moisturizing duration was confirmed, and the results showed that the patch of the present invention effectively maintained a high skin moisture content for 24 hours after application. The 24-hour moisturizing duration test revealed that the patch of the present invention increased skin moisture content by an average of 35%, and maintained a moisture retention capacity that was 28% or more higher even after 24 hours.

[0145] The UV blocking effect was evaluated by measuring the blocking performance against UV-A and UV-B rays, and the results confirmed that it effectively protects against UV rays that induce skin irritation. The UV blocking effect was evaluated by measuring the blocking performance against UV-A and UV-B rays, and the UV protection factor (SPF) recorded was 50 or higher. It showed an average blocking effect of more than 95% against UV rays that induce skin irritation.

[0146] Furthermore, the evaluation of adhesion due to sweat after exercise was performed by measuring the adhesion retention of the patch after the subjects exercised on a treadmill for 30 minutes. In the experiment, the state of the patch before and after adhesion was recorded and analyzed using a strain gauge and a high-resolution camera. The degree to which the patch was firmly held in place through the strain generated on the skin area to which it was attached was confirmed, and the degree to which the adhesion of the patch was retained by sweat after exercise was evaluated. The adhesion retention rate was calculated based on the percentage of the area in which the patch remained in contact with the skin without falling off, and the average adhesion retention rate after patch attachment was measured to be 98%. This value was calculated considering the percentage of the area in skin contact that decreased or where adhesion weakened, demonstrating that the patch of the present invention maintains strong adhesion even with sweat generated during exercise.

[0147] The improvement in skin tone and the reduction of dark circles were assessed through subjective evaluations by research participants and professional skin analysis equipment. After two weeks of application, over 80% of users reported a more uniform improvement in skin tone, and over 75% reported a positive reduction in dark circles. User satisfaction was high, with over 90% of users citing the transparency and inconspicuousness of the patch as its greatest advantages. Furthermore, over 85% of users experienced a rapid reduction in skin irritation due to the soothing effect of the patch.

[0148] The description of the presented embodiments is provided so that any person with ordinary skill in the art of the invention may utilize or implement the invention. Various modifications to such embodiments are obvious to a person with ordinary skill in the art of the invention, and the general principles defined herein can be applied to other embodiments without departing from the scope of the invention. Accordingly, the invention is not limited to the embodiments presented herein and should be interpreted in the broadest sense consistent with the principles and novel features presented herein. [Explanation of Symbols]

[0149] 1000 Transparent Skin Patches 10 Hydrogel film 100 surface layer 200 Middle Class 300 Skin contact layer

Claims

1. It is composed of a hydrogel mixture, and comprises a surface layer that forms the surface, An intermediate layer is provided in contact with one surface of the surface layer and is formed by mixing a first mixture that provides an ultraviolet blocking function with a second mixture containing the hydrogel mixture, A transparent patch for the skin, comprising: a skin contact layer that contacts one surface of the intermediate layer and comprises the hydrogel mixture.

2. The hydrogel mixture is It contains distilled water, acrylamide, hydrophilic polymer, methylenebisacrylamide (MBA), and ammonium persulfate (APS), The aforementioned hydrophilic polymer is a polymeric substance that has hydrophilic properties and absorbs moisture. A transparent skin patch according to claim 1, comprising at least one of agarose, chitin, chitosan, gelatin, hyaluronic acid, carboxymethylcellulose (CMC), and polyvinyl alcohol (PVA).

3. The distilled water is provided in an amount of 50 to 55 parts by weight per 100 parts by weight of the hydrogel mixture. The acrylamide is provided in an amount of 40 to 45 parts by weight per 100 parts by weight of the hydrogel mixture. The hydrophilic polymer portion is provided in an amount of 5 to 10 parts by weight per 100 parts by weight of the hydrogel mixture. The methylenebisacrylamide is provided in an amount of 0.025 to 0.030 parts by weight per 100 parts by weight of the hydrogel mixture. The transparent skin patch according to claim 2, wherein the ammonium persulfate is provided in an amount of 0.125 to 0.130 parts by weight per 100 parts by weight of the hydrogel mixture.

4. The first mixture is It contains avobenzone, ethylhexyl salicylate, homosalate, and octocrylene. The avobenzone is provided in an amount of 10 to 15 parts by weight per 100 parts by weight of the first mixture. The ethylhexyl salicylate is provided in an amount of 15 to 20 parts by weight per 100 parts by weight of the first mixture. The homosalate is provided in an amount of 35 to 40 parts by weight per 100 parts by weight of the first mixture. The transparent skin patch according to claim 1, characterized in that the octocrylene is provided in an amount of 35 to 40 parts by weight per 100 parts by weight of the first mixture.

5. The aforementioned intermediate layer is The transparent skin patch according to claim 1, wherein the first mixture and the second mixture are mixed in a ratio ranging from 20 parts by weight to 80 parts by weight to 30 parts by weight to 70 parts by weight, respectively.

6. The aforementioned intermediate layer is The transparent skin patch according to claim 1, further comprising zinc oxide (ZnO) and a glycol-based solution.

7. The aforementioned zinc oxide is It is dispersed in the form of particles smaller than 100 nm in size. The aforementioned particles are A transparent skin patch according to claim 6, comprising at least one shape from spherical, plate-like, rod-like, and irregular.

8. In a method for manufacturing a transparent skin patch that adheres to the user's skin, A step of generating a skin contact layer, The steps include generating an intermediate layer on one surface of the skin contact layer, The steps include generating a surface layer on one surface of the intermediate layer, Includes, A method for producing a transparent patch for skin, characterized in that the skin contact layer, the intermediate layer, and the surface layer are composed of a hydrogel mixture.

9. The step of generating the aforementioned intermediate layer is: A step of producing a first mixture, A step of adding acrylamide, zinc oxide, and a hydrophilic polymer to distilled water to produce an initial mixture, The steps include adding methylenebisacrylamide to the initial mixture and mixing, A mixing step in which the first mixture is added to the initial mixture containing the methylenebisacrylamide and mixed, The steps include adding ammonium persulfate to the mixing mixture and performing a mixing process, The process involves a film formation step based on the final mixture after mixing to generate a film-like intermediate layer, followed by a curing step, A method for producing a transparent skin patch according to claim 8, including the method described in claim 8.

10. The step of producing the first mixture is: A step of mixing avobenzone, ethylhexyl salicylate, homosalate and octocrylene to produce a first initial mixture, A step of adding a glycol-based solution to the first initial mixture to produce the first mixture, A method for producing a transparent skin patch according to claim 9, including the method described in claim 9.

Images