High-concentration antibody-containing solution preparation
JP2026094237APending Publication Date: 2026-06-09CHUGAI PHARMA CO LTD +1
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- CHUGAI PHARMA CO LTD
- Filing Date
- 2026-02-24
- Publication Date
- 2026-06-09
AI Technical Summary
Benefits of technology
【0010】 凍乾濃縮による再構成の必要がなく、再溶解の手間が要らない、高濃度抗体含有製剤が提供される。本発明の高濃度抗体含有製剤は溶液状態で安定に長期保存可能であり、製造過程に凍結乾燥工程を含まないで製造することができるため、凍結保護剤としての糖などの添加が不要である。
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Abstract
To provide a stable antibody-containing formulation suitable for subcutaneous administration, in which dimerization and deamidation during long-term storage are suppressed. [Solution] A stable antibody-containing solution formulation characterized by containing arginine and methionine.
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