Anti-inflammatory drugs

Methoxyflavones, particularly 5,7,3',4'-Tetramethoxyflavone, are used to inhibit IL-6 and TNF-α production, addressing persistent inflammation in elderly individuals and reducing inflammatory markers, showing efficacy in cell and animal models.

JP2026116005APending Publication Date: 2026-07-09NAT UNIV CORP EHIME UNIV +1
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
NAT UNIV CORP EHIME UNIV
Filing Date
2024-12-27
Publication Date
2026-07-09

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Abstract

The present invention provides an anti-inflammatory agent containing a specific methoxyflavone. [Solution] An anti-inflammatory agent (excluding intestinal barrier function improving agents) comprising a compound represented by formula (II), or a pharmaceutically acceptable salt, glycoside, or esterified thereof: TIFF2026116005000037.tif60170 (In the formula, R 1 , R 2 , R 3 , R 4 , and R 5 represents a linear or branched alkyl group having 1 to 6 carbon atoms. l, m, n, p, and q represent 0, 1, or 2. However, the sum of l, m, and n is 3 or less. The sum of p and q is 2 or less.
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