Intraocular lenses with power coefficients and structures for improved peripheral vision

Abstract

Lenses and methods are provided to improve a patient's peripheral and central vision. The lenses improve visual acuity by having optical elements configured to provide optimal peripheral vision, for example, minimizing off-axis astigmatism with a 20-degree eccentricity, while maximizing axial visual acuity and contrast sensitivity. The method provides an IOL design that reduces optical errors in the image generated at a peripheral retinal position of the patient's eye, positioned at a certain distance from the fovea, while maximizing axial visual acuity and contrast sensitivity.

Description

[Technical Field]

[0001] Embodiments of this disclosure relate to apparatus, systems, and methods for manufacturing intraocular lenses that provide not only corrected visual acuity but also improved peripheral vision. [Background technology]

[0002] Embodiments of this disclosure relate to vision treatment technologies, and more particularly to ophthalmic lenses such as intraocular lenses (IOLs), including, for example, phakic IOLs and piggyback IOLs (i.e., IOLs implanted in eyes that already have IOLs).

[0003] Intraocular lenses (IOLs) can be used to restore visual function after cataracts or other ophthalmic procedures, either by replacing the natural lens with an IOL or by supplementing it with an IOL implant. When such procedures alter the optics of the eye, the goal is generally to improve visual acuity, typically in the central visual field. Recent studies have found that when a monofocal IOL is implanted, peripheral aberrations change, and these aberrations differ significantly from those of a normal phakic eye. The primary changes are observed with respect to peripheral astigmatism (astigmatism), the main peripheral aberration in the natural eye, followed by spherical aberrations, and then higher-order aberrations. Such changes can affect overall functional visual acuity, including driving ability, risk of falls, postural stability, and / or detection ability.

[0004] Additionally, certain retinal conditions, such as age-related macular degeneration (AMD) or central scotoma, can impair central vision. Even at very young ages, other conditions like Stargardt disease, Best's disease, and reverse retinitis pigmentosa can affect central vision. Visual outcomes in patients with these conditions can be improved by improving peripheral vision.

[0005] Peripheral vision can also be worsened by glaucoma. Glaucoma affects 2% of the population over the age of 40. People with glaucoma gradually lose peripheral vision as a result of damage to the optic nerve. Central vision may worsen in the very later stages of the disease. Significant impairments in daily life, including problems with walking, balance, fall risk, and driving, can result from glaucoma. People with glaucoma can benefit from IOLs that improve both central and peripheral vision. [Overview of the Initiative] [Problems that the invention aims to solve]

[0006] In light of the above, lenses that improve peripheral vision are needed. [Means for solving the problem]

[0007] The present invention solves the above problems and thus improves peripheral vision by providing a lens having a range of power-shape coefficients and diopter-indicating powers corresponding to a lens having optimized axial visual acuity and contrast sensitivity and a blur parameter of less than 1.8 diopters (D). Furthermore, a lens is provided having a shape coefficient and diopter-indicating power that falls within a partial range corresponding to an optimal peripheral vision lens that maximizes axial visual acuity and contrast sensitivity while minimizing off-axis astigmatism at a 20-degree eccentricity, the optimization parameters of which are described herein.

[0008] In particular, the first embodiment of the intraocular lens comprises a lens body, the lens body including a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 17D to 23D including both ends, and a power-shape factor of -1.0 or less and -2.5 or greater. Advantageously, providing an intraocular lens according to the indication power range and power-shape factor range of the first embodiment allows for correction of peripheral astigmatism according to a blur parameter of less than 1.8D while optimizing axial visual acuity. Within these ranges, the power-shape factor is stable, meaning that structural elements can be selected to produce a lens that predictably produces the effect of reducing off-axis astigmatism with a 20-degree eccentricity while optimizing axial visual acuity. These ranges are crucial for enabling predictable correction of peripheral astigmatism for patients with diopter power requirements less than the transition point power, which is the indication power corresponding to the shape factor of a plano-convex lens of -1.

[0009] The lens body may include a central thickness of 0.62 mm to 1.0 mm. The intraocular lens may further include an anterior haptic connected to the lens body, and the lens may include a vault height of 0.34 mm to 0.65 mm. The lens has a -0.077 mm -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.355 mm -1 Exceeding -0.130mm -1 It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to fall within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from becoming excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the range of the invention, further contributing to the lens's ability to improve peripheral vision as predicted.

[0010] The lens may include diopter indication powers of 18D to 22D, including both ends. The power-shape factor may be -1.1 or less and -2.0 or greater. Advantageously, these ranges of indication power and power-shape factor result in lenses optimized to minimize off-axis astigmatism while maximizing on-axis visual acuity for lenses with indication powers below the transition point power. Across these ranges, the power-shape factor of the lens is particularly stable, which is crucial to enable a superior ability to predict the structural elements of the lens that result in optimization. The lens may include a center thickness of 0.70mm to 0.90mm. Anterior haptics may be connected to the lens body, and the lens may include a vault height of 0.40mm to 0.60mm. The lens may have a -0.071mm -1 Exceeding -0.00 mm -1 Front curvature less than -0.355mm -1 Exceeding -0.134mm -1 The first surface may have a posterior curvature of less than . Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges for each parameter also prevent the lens from being excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the optimization range, further contributing to the lens's ability to predictably minimize peripheral vision while maximizing axial visual acuity.

[0011] The degree-shape factor can be calculated using the paraaxially defined radii of curvature of the first and second surfaces.

[0012] With respect to the optical axis of the lens, the first surface of the lens may be concave, and the second surface may be convex. The concave surface may include a front surface curvature radius that is larger than the rear surface curvature radius of the convex surface.

[0013] The frequency shape coefficient is given by the formula

[0014] [Number] can be calculated according to, where the power 前 is the front power of the lens body, and the power 後 is the back power.

[0015] The power shape factor can be calculated by ray tracing techniques applied to the intraocular lens. The ray tracing technique may include using a specific aperture diameter. The ray tracing technique may include using a specific aperture diameter, the best focus position, and the spherical aberration effect on the power shape factor.

[0016] A second embodiment of the intraocular lens includes a lens body having a refractive index of 1.50 to 1.60 including both ends, a dioptric power display of 20D to 28D including both ends, and a power shape factor of -1.0 or less and -3 or more. Advantageously, providing an intraocular lens according to the power display range and power shape factor range of the second embodiment enables correction of peripheral astigmatism according to a blur parameter of less than 1.8D while optimizing the on-axis vision. Within these ranges, the power shape factor is stable, which means that structural elements can be selected to produce a lens that can predictably produce an effect of reducing off-axis astigmatism at an eccentricity of 20 degrees while optimizing the on-axis vision. These ranges are important to enable predictable correction of peripheral astigmatism for patients with dioptric power requirements less than the transition point power. The transition point power is the power display corresponding to the shape factor of a plano-convex lens of -1.

[0017] The lens may include a central thickness of 0.45 mm to 1.0 mm. The intraocular lens may further include a front haptic connected to the lens body, and the lens may include a bolt height of 0.30 mm to 0.65 mm. The lens has a first surface with a front curvature greater than -0.022 mm -1 and less than 0.00 mm -1 and a second surface with a back curvature greater than -0.170 mm -1 and less than -0.081 mm -1It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to fall within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from becoming excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the range of the invention, further contributing to the lens's ability to improve peripheral vision as predicted.

[0018] The lens may include diopter powers ranging from 20D to 27D. The power-shape factor may be between -1.0 and -2.4. An advantage is that these ranges of power and power-shape factor are crucial for achieving a lens optimized to minimize off-axis astigmatism while maximizing on-axis visual acuity. Across these ranges, the lens's power-shape factor is particularly stable, which allows for a superior ability to predict the structural features of the lens that result in optimization. This enables the optimization of peripheral astigmatism correction for patients with diopter power requirements below the transition point power. The lens may include a central thickness of 0.55mm to 0.90mm. An anterior haptic may be connected to the lens body, and the lens may include a vault height of 0.35mm to 0.60mm. The lens may have a -0.022mm diameter. -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.170 mm -1 Exceeding -0.084mm -1It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from being excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the optimization range, further contributing to the lens's ability to minimize peripheral vision as predicted while maximizing axial visual acuity.

[0019] The degree-shape factor can be calculated using the paraaxially defined radii of curvature of the first and second surfaces.

[0020] With respect to the optical axis of the lens, the first surface of the lens may be concave, and the second surface may be convex. The concave surface may include a front surface radius of curvature that is larger than the rear surface radius of curvature of the convex surface.

[0021] The frequency shape coefficient is given by the formula:

[0022]

number

[0023] The power-shape factor can be calculated by ray tracing techniques applied to intraocular lenses. Ray tracing techniques may include utilizing a specific aperture diameter. Ray tracing techniques may include utilizing a specific aperture diameter, the best focal position, and the spherical aberration effect on the power-shape factor.

[0024] A third embodiment of the intraocular lens comprises a lens body, the lens body having a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 23D to 30D including both ends, and a power-shape factor of -0.2 or less and -1 or greater. Advantageously, providing an intraocular lens according to the indication power range and power-shape factor range of the third embodiment allows for correction of peripheral astigmatism according to a blur parameter of less than 1.8D while optimizing axial visual acuity. Within these ranges, the power-shape factor is stable, meaning that structural elements can be selected to produce a lens that predictably produces the effect of reducing off-axis astigmatism with a 20-degree eccentricity while optimizing axial visual acuity. The scope of the third embodiment of the present invention is crucial for enabling correction of peripheral astigmatism for patients with diopter power requirements exceeding a transition point power. The transition point power is the indication power corresponding to a plano-convex lens shape factor of -1.

[0025] The lens may include a center thickness of 0.62mm to 1.0mm. The front haptic may be connected to the lens body, and the lens may include a vault height of 0.34mm to 0.65mm. The lens is 0mm -1 Exceeding 0.120 mm -1 A first surface having a front curvature of less than -0.367 mm -1 Exceeding -0.130mm -1 It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to fall within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from becoming excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the range of the invention, further contributing to the lens's ability to improve peripheral vision as predicted.

[0026] The lens may include diopter powers of 24D to 29D, including both ends. The power-shape factor is -0.3 or less and -0.8 or greater. Advantageously, these ranges of power and power-shape factor are crucial for resulting in a lens optimized to minimize off-axis astigmatism while maximizing on-axial visual acuity. Across these ranges, the lens's power-shape factor is particularly stable, which allows for a superior ability to predict the structural features of the lens that result in optimization for patients with diopter power requirements exceeding the transition point power. The lens may include a center thickness of 0.70mm to 0.90mm. Anterior haptics may be connected to the lens body, and the lens may include a vault height of 0.40mm to 0.60mm. The lens is 0mm -1 Exceeding 0.12 mm -1 A first surface having a front curvature of less than -0.36 mm -1 Exceeding -0.13mm -1 It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from being excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have an even more stable power-shape coefficient within the range of minimization, further contributing to the lens's ability to predictably minimize peripheral vision while maximizing axial visual acuity.

[0027] The degree-shape factor can be calculated using the paraaxially defined radii of curvature of the first and second surfaces.

[0028] The frequency shape coefficient is given by the formula:

[0029]

number

[0030] The power-shape factor can be calculated by ray tracing techniques applied to intraocular lenses. Ray tracing techniques may include utilizing a specific aperture diameter. Ray tracing techniques may include utilizing a specific aperture diameter, the best focal position, and the spherical aberration effect on the power-shape factor.

[0031] A fourth embodiment of the intraocular lens comprises a lens body, the lens body having a refractive index of 1.50 to 1.60 including both ends, a diopter power of 23D to 35D including both ends, and a power-shape factor of -0.2 or less and -1 or greater. Advantageously, providing an intraocular lens according to the power-to-aspect range and power-shape factor range of the first embodiment allows for correction of peripheral astigmatism according to a blur parameter of less than 1.8D while optimizing axial visual acuity. Within these ranges, the power-shape factor is stable, meaning that structural elements can be selected to produce a lens that predictably produces the effect of reducing off-axis astigmatism with a 20-degree eccentricity while optimizing axial visual acuity. The scope of the fourth embodiment of the present invention is crucial for enabling correction of peripheral astigmatism for patients with diopter power requirements exceeding a transition point power. The transition point power is the power-to-aspect corresponding to a plano-convex lens shape factor of -1.

[0032] The lens may include a center thickness of 0.45mm to 1.0mm. The front haptic may be connected to the lens body, and the lens may include a vault height of 0.30mm to 0.65mm. The lens may have a thickness of 0.00mm -1 exceeding 0.082 mm -1 A first surface having a front curvature of less than -0.179 mm -1 Exceeding -0.081mm -1It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to fall within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from becoming excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the range of the invention, further contributing to the lens's ability to improve peripheral vision as predicted.

[0033] Intraocular lenses may have diopter indication powers of 25D to 35D, including both ends. The power-shape factor may be -0.40 or less and -0.95 or greater. Advantageously, these ranges of indication power and power-shape factor are crucial for resulting in a lens optimized to maximize axial visual acuity while minimizing off-axial astigmatism. Across these ranges, the lens's power-shape factor is particularly stable, which allows for a superior ability to predict the structural features of the lens that result in optimization for patients with diopter power requirements exceeding the transition point power. The lens may include a central thickness of 0.55mm to 0.90mm. Anterior haptics may be connected to the lens body, and the lens may include a vault height of 0.35mm to 0.60mm. The lens may have a diameter of 0.01mm. -1 exceeding 0.082 mm -1 A first surface having a front curvature of less than -0.179 mm -1 Exceeding -0.081mm -1It may comprise a second surface having a posterior curvature of less than . Advantageously, selecting any of these parameters to be within their respective ranges increases the adaptability of the lens by allowing it to be implanted using industrially available inserters. These ranges of each parameter also prevent the lens from being excessively steep, thereby reducing discomfort when inserted into the patient. Each selection of these parameters further allows the lens to have a more stable power-shape coefficient within the optimization range, further contributing to the lens's ability to minimize peripheral vision as predicted while maximizing axial visual acuity.

[0034] The degree-shape factor can be calculated using the paraaxially defined radii of curvature of the first and second surfaces.

[0035] The frequency shape coefficient is given by the formula:

[0036]

number

[0037] The power-shape factor can be calculated by ray tracing techniques applied to intraocular lenses. Ray tracing techniques may include utilizing a specific aperture diameter. Ray tracing techniques may include utilizing a specific aperture diameter, the best focal position, and the spherical aberration effect on the power-shape factor.

[0038] The present invention also provides a set of intraocular lenses for improving peripheral vision, comprising at least one lens according to a first and / or second embodiment, and at least one lens according to a third and / or fourth embodiment. The provision of the lens set enables the correction of peripheral vision for prescriptions requiring a diopter power less than the transition point power, in addition to the correction of peripheral vision for prescriptions having a diopter power exceeding the transition point power. The transition point power may be a display power corresponding to a shape factor of -1. Thus, the lens set of the present invention enables the correction of peripheral vision across the entire range of possible prescriptions, and the fitting of lenses provided based on prescriptions.

[0039] At least one lens may comprise a set of lenses, each of which differs by at least 0.25D in diopter power. Advantageously, this set may provide a range of lenses that can be selected by the user to match the patient's diopter power requirements, both for lenses below and above the transition point.

[0040] The present invention also relates to a method for designing a set of intraocular lenses for improved peripheral vision, wherein the power-shape factor increases from -2.5 to -0.2 as the indicated power of the lens increases from 17D to 30D, and this method The invention includes providing an IOL having an optical power that reduces optical errors in the image produced at a peripheral retinal position of the patient's eye, positioned at a certain distance from the fovea, for each display power increment of at least 0.25D, For display powers having a shape factor of -1 or less, the IOL comprises a lens body formed according to the first and / or second embodiment, For display powers having a shape factor of -1 or greater, the IOL comprises a lens body formed according to the third and / or fourth embodiment, The blur parameter of each IOL is less than 1.8 diopters, and the blur parameter is given by the formula:

[0041]

number

[0042] [Figure 1] This example illustrates a conventional technique that uses an intraocular lens having a concave front surface and a convex rear surface to adjust the focal length of the peripheral image formed on the retina of the eye. [Figure 2] This is a diagram of an intraocular lens according to some embodiments of the present disclosure. [Figure 3] This invention provides a graphical representation and corresponding formula for calculating surface degree values ​​from the respective refractive indices and radii of curvature according to embodiments of this disclosure. [Figure 4] This is a graph of a peripheral vision lens with a refractive index of 1.471. [Figure 5] This is a graph representing a peripheral vision lens with a refractive index of 1.55. [Figure 6] This is a graph showing the shape factor and the region of the indicated power for a lens having a refractive index of 1.471, optimized according to the considerations of this specification. [Figure 7] This is a graph showing the shape factor and the region of the indicated power for a lens having a refractive index of 1.55, optimized according to the considerations of this specification. [Modes for carrying out the invention]

[0043] This disclosure examines several types of ophthalmic lenses used to correct vision, presents reliable solutions to problems associated with the implantation of intraocular lenses into patients, and provides reliable positioning for structural elements of IOLs with different powers.

[0044] Embodiments of this disclosure incorporate the plain meaning of technical terms within the art of IOLs. For example, as shown in Figure 2, this disclosure refers to a haptic 320 attached to the lens body, which is equipped to hold the IOL 300 in a fixed position within the patient's eye. The haptic 320 establishes an anterior haptic plane 325, which is a useful reference point for the purpose of comparing different lenses. The anterior haptic plane 325 is defined by a plane that is perpendicular to the optical axis and extends across the frontmost surface of the incompressible IOL haptic 320. As shown in Figure 2, the vault height 350 of the IOL is the distance between the anterior haptic plane 325 and a plane perpendicular to the optical axis that is in contact with the front surface 330 of the IOL body, calculated as defined in ISO standard 11979-1. Figure 2 also shows a measurement of the central thickness 310, which is the difference between the sagittal thickness and the vault height as defined in ISO standard 11979-1. The intraocular lens body in Figure 2 has a front surface 330, a posterior surface 340, an anterior principal plane 300 at least partially determined by the optical effect of the front surface of the IOL, and a posterior principal plane 300 at least partially determined by the optical effect of the posterior surface of the IOL. In this disclosure, the best possible structure is calculated for a given indicated power measured in diopters. As used herein, “indicated power” refers to the diopter power as defined in ISO standard 11979-1, which can be calculated using ray tracing techniques. The central thickness 310, front surface curvature, and posterior surface curvature are used in accordance with standards in the art of intraocular lenses. Standard materials for forming the IOL are within the scope of this disclosure. In various embodiments, the optical elements may include materials such as acrylic, silicone, polymethyl methacrylate (PMMA), styrene-ethylene-butylene-styrene block copolymer (C-FLEX), or other styrene copolymers, polyvinyl alcohol (PVA), polystyrene, polyurethane, and hydrogel.

[0045] This disclosure uses the power-shape coefficient values ​​of the intraocular lens (IOL) to identify the structural elements of the IOL necessary to achieve different indicated powers measured at the appropriate diopter (D) at the time of implantation in the patient. By controlling and designing at least the structural elements disclosed herein and shown in Figure 2 and Equations 1-10 below, the IOLs of this disclosure demonstrate extremely high performance in treating ocular diseases and maintaining focus and clarity for both foveal and peripheral vision in patients receiving implanted IOLs.

[0046] As an initial introduction, this disclosure uses at least two different IOL structures configured as peripheral vision corrective IOLs as non-limiting examples illustrating the features and benefits of the research disclosed herein. Figure 2 illustrates a lens in which the concave surface faces the object to be imaged and / or the light source of the image. The IOL may have convex surfaces on both the front and rear sides of the IOL. A plano-convex IOL has a flat or substantially flat front surface and a convex rear surface.

[0047] The power-shape factor varies for different types of lenses, but may be constant for lenses having a single plane. For example, a constant power-shape factor is equal to -1 for a plano-convex lens. In non-limiting embodiments, IOLs are provided that have a power-shape factor of -1 or less, and also IOLs that have a power-shape factor of -1 or greater. IOLs with a power-shape factor of -1 or greater may have a lens body that is formed differently from that of IOLs with a power-shape factor of -1 or less. Without limiting this disclosure to any particular power-shape factor or indicated power, the lenses of this disclosure may have an indicated power range of about 17D to 35D to illustrate various embodiments. For a constant power-shape factor of a plano-convex lens (e.g., -1), the lens shape transitions from that of lenses with a power-shape factor of -1 or less to those of lenses with a power-shape factor of -1 or greater. In lower display frequency ranges, including but not limited to the 7D–17D range, the anterior and posterior surfaces of an IOL do not necessarily exhibit the frequency responsiveness expected from a simple surface with consistent curvature across the anterior and posterior surfaces. Instead, the anterior and posterior surfaces of an IOL may effectively contain complex surfaces that vary across each surface. Dispersion across surfaces may relate to variations in surface curvature (i.e., exhibiting toroidal surface structures or Zernike surfaces) and may require further investigation to ensure that the desired reliable response is provided at the time of IOL implantation in the patient.

[0048] The frequency shape coefficient of IOL is given by the formula:

[0049]

number

[0050] The front frequency is given by the formula:

[0051]

number

[0052] The rear angle is given by the formula:

[0053]

number

[0054] The radius of curvature shape coefficient of IOL is given by:

[0055]

number

[0056] The lens manufacturer's formula illustrates how the focal length of an intraocular lens is affected by the radii of curvature of both the anterior and posterior surfaces, where F is the focal length and n IOLR is the refractive index of the lens, R1 is the radius of curvature of the first surface, and R2 is the radius of curvature of the second surface.

[0057]

number

[0058] Conventional approaches, such as the IOL100 shown in Figure 1, have focused on lens manufacturers' formulas for adjusting the radius and focal length of the IOL, without conducting in-depth analysis of the variable power response that the front and rear surfaces may exhibit during implantation.

[0059] The measurements cited throughout this application are considered in relation to the Liou and Brennan eye model (Liou HL, Brennan NA. Anatomically accurate, finite model eye for optical modeling. J Opt Soc Am A Opt Image Sci Vis. 1997 Aug;14(8):1684-95. doi:10.1364 / josaa.14.001684. PMID:9248060). For the lenses of this disclosure, the vault height range is selected from 0.34 mm to 0.65 mm. The lenses may include vault heights in the range of 0.40 mm to 0.60 mm or 0.50 mm to 0.55 mm. The vault height may be 0.65 mm. The center thickness is selected from the range of 0.62 mm to 1.0007 mm. The central thickness may be in the range of 0.70 mm to 0.90 mm, or 0.80 mm to 0.85 mm. The shape factor may be in the range of -4 to 0. These parameter ranges are selected to provide lenses that can be implanted using injectors available in the industry, and to avoid producing lenses that are excessively steep, thereby reducing patient discomfort. For these reasons, lenses with a posterior radius smaller than -4 mm are also excluded from this disclosure. In this disclosure, the axial length is fixed by the paraaxial focus of an equivalent ZCB00 (Tecnis® monofocal) lens having a power 2D less than the indicated power of the IOL (i.e., an IOL with an indicated power of 22D uses the axial length corresponding to a 20D ZCB00 lens).

[0060] An implanted IOL can be classified as a peripheral vision correcting lens if, for an implanted IOL, the off-axis astigmatism measured at a 20-degree eccentricity, measured from the optical axis passing through the iris, is below a threshold of 1.8D. Eccentricity refers to the angular distance from the center of the visual field, such as the fovea. Off-axis astigmatism at 20 degrees can be calculated according to the peripheral blur parameter of the IOL measured at that angle. For example, for an IOL with a stated power of 20D that corrects peripheral vision, the peripheral astigmatism may be 1.3D or 1.7D at a 20-degree eccentricity.

[0061] Vectors J0 and J 45 Furthermore, spherical frequency, cylindrical frequency, and blur parameter can be calculated. These values ​​are calculated according to the following formulas, where C(i,j) is the corresponding Zernike coefficient in μm and r is the pupillary radius in mm. For these formulas, the rule of negative signs is used for the definition of cylinder, and retinal curvature is defined according to Atchinson et al. (Optical models for human myopic eyes, 2006).

[0062]

number

[0063] Referring to Figures 4 and 5, this disclosure provides a range of lenses having a display power that corrects peripheral vision according to blur parameter conditions, has an absolute value of less than 1.8D for peripheral cylindrical power at a 20-degree eccentricity, and optimizes axial visual acuity and contrast sensitivity. Axial visual acuity and contrast sensitivity are optimized for selected values ​​of vault height, center thickness, and shape factor within the ranges considered herein. For the selected values, axial visual acuity and contrast sensitivity are optimized by adjusting the front and / or rear aspherical parameters to produce lenses having axial performance as close as possible to the diffraction-limited performance of an entrance pupil of 5.65 mm on-axially in green light (550 nm). Graph 400 in Figure 4 shows a peripheral vision lens with a refractive index of 1.471 that corrects peripheral vision according to the blur parameter conditions, has an absolute value of less than 1.8D for the cylindrical power at a 20-degree eccentricity, and optimizes axial visual acuity and contrast sensitivity, while Graph 500 in Figure 5 shows a peripheral vision lens with a refractive index of 1.55 that corrects peripheral vision according to the blur parameter conditions, has an absolute value of less than 1.8D for the peripheral cylindrical power at a 20-degree eccentricity, and optimizes axial visual acuity. Figures 4 and 5 show plots of the shape factor against the indicated power of lenses that satisfy the conditions, respectively. In both plots, the lenses are constrained by having a vault height of 0.34 mm to 0.65 mm and a central thickness in the range of 0.62 mm to 1.0007 mm.

[0064] Referring to graphs 600 and 700 in Figures 6 and 7, respectively, the disclosure also provides sub-ranges corresponding to optimal display powers and power-shape factors, which are critical for peripheral vision lenses that maximize the reduction of off-axis astigmatism at a 20-degree eccentricity while maximizing axial visual acuity and contrast sensitivity. Figure 6 shows the optimal regions for a refractive index of 1.471 as shaded regions 610 and 620. Figure 7 shows the optimal regions for a refractive index of 1.55 as shaded regions 710 and 720. In both graphs, the lens is constrained by having a vault height of 0.34 mm to 0.65 mm and a center thickness in the range of 0.62 mm to 1.0007 mm.

[0065] To calculate these subranges corresponding to regions 610, 620, 710, and 720, the modulation transfer function (MTF) was optimized. Contrast sensitivity is known to be proportional to the modulation transfer function (MTF), and therefore, sufficient axial visual acuity and / or contrast sensitivity can be achieved by optimizing the MTF. Optimization can be performed at one or more spatial frequencies, or using a performance index proportional to the MTF level at one or more spatial frequencies. In a non-limiting example, sufficient contrast sensitivity is achieved if the MTF is at least 0.7 for a 5mm pupil in green light at a spatial frequency of 50 cycles / mm, when measured using eye model #2 according to ISO 11979-2 2014. The following parameters and their associated weightings for MTF optimization are as follows: axial diffraction-limited lens for a large 5.65 mm entrance pupil (weight = 1), reducing off-axis astigmatism and off-axis focus blur at 20 degrees for a 4 mm entrance pupil (weight = 0.01 each), increasing the off-axis MTF values ​​at 20 degrees for both sagittal and tangential focals at a spatial frequency of 25 cycles / mm for a 4 mm entrance pupil (weight = 0.02 each), and making the off-axis MTF values ​​at 20 degrees for both sagittal and tangential focals at a spatial frequency of 25 cycles / mm as similar as possible for a 4 mm entrance pupil (weight = 0.01). MTF was calculated using 550 nm monochromatic green light, along with the anterior haptic plane of the lens approximately 0.5 mm posterior to the iris in the Liou and Brennan eye model, and with retinal curvature defined according to Atchinson et al. Optical models for human myopic eyes, 2006). This optimization can be used to determine how lens parameters such as vault height, central thickness, front and rear curvature, and shape factor can be adjusted (according to the lens manufacturer's formula) to achieve a desirable partial range of optimal display power to improve the patient's peripheral vision.Next, taking into consideration the appropriate selection of structural elements, a subrange was chosen according to the region where the observed optimization was most stable, so that the optimization effect could be predictable.

[0066] Figure 3 shows an example of IOL characteristics by considering the refractive indices of the medium in front of the lens (n1), the lens material (n2), and the medium behind the lens (n3). Using the known radii of curvature (R1, R2) of the front and rear surfaces of the lens, the surface power of the lens (i.e., power) 前 and frequency 後 ) can be calculated according to formulas 2 and 3 listed above. Frequency 前 Regarding n 媒体 However, n 1- Corresponding to, the degree 後 Regarding n 媒体This corresponds to n2. The disclosure includes surface curvature values ​​over a number of diopter-expressed powers for the front and rear surfaces of a number of different lenses, each having a respective refractive index. The disclosure considers IOLs having a power-shape factor of -1 or less, and / or IOLs having a power-shape factor of -1 or greater. The lens body of an IOL having a power-shape factor of -1 or less may be formed differently from the lens body of an IOL having a power-shape factor of -1 or greater. The disclosure may provide a set of lenses comprising at least one first lens having a power-shape factor of -1 or less. Additionally or alternatively, the set of lenses may comprise at least one second lens having a power-shape factor of -1 or greater. Lenses having a power-shape factor of -1 or less and / or lenses having a power-shape factor of -1 or greater may have refractive indices (n2) of 1.40 to 1.50 and / or refractive indices (n2) of 1.50 to 1.60. Other refractive index ranges are also considered. The refractive index may be 1.45 to 1.48. The refractive index may be 1.54 to 1.56. The refractive index may be 1.471. The refractive index may be 1.55. Each power-shape factor and the radius of curvature for different refractive indices are consistent with established patterns for the lenses considered above. Indeed, the differences and similarities between the power-shape factors of the lenses considered above exhibit patterns useful for predicting the effects of lens elements, such as, but not limited to, the vault heights considered above. These same effects may be demonstrated in further testing of lenses with variable refractive index values ​​disclosed herein.

[0067] This disclosure describes structural factors of IOLs that showed exceptional results in foveal and peripheral vision upon implantation according to the optimizations discussed herein.

[0068] Lenses with a power shape coefficient of -1 or less As described above, and as shown in Figures 4-7, certain lower powers, for example, lenses with a power-shape factor of -1 or less, exhibit less stable power-shape factor values ​​across a range of lower powers. This lower power range may be 7D to 17D. As further shown by Figures 4-7, similar uncertainty is observed for lenses with a power-shape factor of -1 or less at higher powers above 28D and below 36D. This provides a basis for fine-tuning the front and rear curvature of each lens at each power. Due to the selection of center thickness, vault height, and shape factor within the range described in this disclosure, the front and rear curvature can be adjusted to produce peripheral vision lenses with stable power response across a range of powers. As shown by Graph 400 in Figure 4, the stable power response range for IOLs with a power-shape factor of -1 or less and a refractive index of 1.40-1.50 is 17D-23D. Referring to Graph 500 in Figure 5, for IOLs with a power shape coefficient of -1 or less and a refractive index of 1.50 to 1.60, the stable range of indicated power is 20D to 28D. Lenses with this indicated range have an easily predictable ability to optimize axial visual acuity to be as close as possible to the diffraction limit while correcting peripheral vision.

[0069] The peripheral vision IOL embodiment comprises a lens body. The lens body has a diopter indication power of 17D to 23D and a refractive index value of approximately 1.40 to 1.50. For these indication powers and refractive indices, the power-shape coefficient is -1 to -2.5. The first surface is -0.77 mm -1 ~0.00mm -1 The front surface may have a curvature of -0.355 mm. -1 ~-0.130mm -1 It may have a rear curvature. The central thickness may be 0.62 mm to 1.0 mm. The front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.34 mm to 0.65 mm.

[0070] In an embodiment of a lens body having a refractive index of approximately 1.50 to 1.60 and a diopter indication power of 20D to 28D, the power shape coefficient is -1 to -3. The first surface is -0.022 mm -1 ~0.00mm -1 The front surface may have a curvature of -0.170 mm. -1 ~-0.081mm -1 It may have a rear curvature. The central thickness may be 0.45 mm to 1.0 mm. The front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.30 mm to 0.65 mm.

[0071] IOLs may be provided that include a lens body fabricated according to the following sub-ranges of indicated power and power shape coefficient. The sub-range of indicated power may be 18D to 22D for lenses with a refractive index of approximately 1.40 to 1.50, and 20D to 27D for lenses with a refractive index of 1.50 to 1.60. Referring to the optimization functions in Figures 6 and 7, the narrow bandwidths 610 and 710 of the optimization functions within these sub-ranges indicate that lenses fabricated with indicated powers within these sub-ranges have more stable shape coefficients over that range compared to the wider ranges considered above. This stability means that it is easier to predict which structural elements will result in a lens that can maximize on-axial visual acuity while minimizing off-axial astigmatism at a 20-degree eccentricity according to the optimized MTF described in this application.

[0072] In one embodiment, the lens has a diopter power of 18D to 22D and a refractive index of 1.40 to 1.50. The lens has a power shape factor of -1.1 to -2.0. In this case, the first surface is -0.071 mm -1 ~-0.00mm -1 The front surface may have a curvature of -0.355 mm. -1 ~-0.134mm -1It may have a rear curvature. The center thickness of the lens may be 0.70 mm to 0.90 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.40 mm to 0.60 mm.

[0073] Further embodiments of the lens have a diopter indication power of 20D to 27D and a refractive index value of 1.50 to 1.60. In this case, the lens has a power shape factor of -1.0 to -2.4. The first surface is -0.022 mm -1 ~-0.00mm -1 The front surface may have a curvature of -0.170 mm. -1 ~-0.084mm -1 It may have a rear curvature. The central thickness may be 0.55 mm to 0.90 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.35 mm to 0.60 mm.

[0074] Lenses with a power shape coefficient of -1 or greater As discussed above, for IOLs with a stated power exceeding the transition point power, the intraocular lens includes a lens body that may be formed differently from the lens body of IOLs with a stated power less than the transition point power. The transition point power may be the stated power corresponding to an IOL with a shape factor of -1. For example, referring to Figure 4, the transition point power may be 23D, 24D, or 25D for lenses with a refractive index of 1.40 to 1.50. Referring to Figure 5, the transition point power may be 23D, 25D, or 28D for lenses with a refractive index of 1.50 to 1.60.

[0075] For lenses with a power-shape coefficient of -1 or greater, the rate of increase in the power-shape coefficient across the range of indicated powers differs, albeit to a smaller degree, than previously considered for indicated powers lower than the transition point power, for higher indicated powers. Referring to Figure 4, between certain increasing indicated powers, the rate of increase in the power-shape coefficient across the range of indicated powers shows little variation. These ranges of indicated powers may be 23D to 30D for lenses with a power-shape coefficient of -1 or greater and a refractive index of 1.40 to 1.50, or 23D to 35D for lenses with a power-shape coefficient of -1 or greater and a refractive index of 1.50 to 1.60. Within these ranges, the front and rear curvatures can be refined to produce easily predictable variations in the shape coefficient across the entire range. This stability increases the lens's ability to predict structural elements, enabling it to correct peripheral vision while optimizing axial visual acuity.

[0076] One embodiment of the lens has a diopter power of 23D to 30D and a refractive index of 1.40 to 1.50. The power-shape factor is -0.2 to -1. For these ranges, the first surface is 0 mm -1 ~0.120mm -1 The front surface may have a curvature of -0.367 mm. -1 ~-0.130mm -1 It may have a rear curvature. The central thickness may be 0.62 mm to 1.0 mm. The front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.34 mm to 0.65 mm.

[0077] An embodiment of a lens having a refractive index of approximately 1.50 to 1.60 has a diopter indication power of 23D to 35D. The power shape factor is -0.2 to -1. In this case, the first surface is 0.00 mm -1 ~0.082mm -1 The front surface may have a curvature of -0.179 mm. -1 ~-0.081mm -1It may have a rear curvature. The central thickness may be 0.45 mm to 1.0 mm. The front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.30 mm to 0.65 mm.

[0078] As shown in region 620 of Figure 6, for lenses with a refractive index of 1.40 to 1.50 and a power-shape factor of -1 or greater, the increase in power-shape factor is determined within at least one exemplary subrange, such as 24D to 29D for lenses with a refractive index of 1.40 to 1.50, or as shown in region 720 of Figure 7, for lenses with a refractive index of 1.50 to 1.60, the increase in power-shape factor is determined such that the difference is not statistically significant and the power-shape factor appears to exhibit better stability. These subranges may be selected to optimize the structural elements of the IOL to result in minimized off-axis astigmatism and maximized on-axis visual acuity at a 20-degree eccentricity, thereby improving peripheral vision. IOLs comprising lens bodies fabricated according to the following subranges of indicated powers and power-shape factors may be provided to maximize on-axis visual acuity while minimizing off-axis astigmatism at a 20-degree eccentricity according to this optimization disclosed herein.

[0079] In a further embodiment of the lens, it has a diopter indication power of 24D to 29D, a refractive index of approximately 1.40 to 1.50, and a power shape factor of -0.3 to -0.8. In this case, the first surface is 0 mm -1 ~0.12mm -1 The front surface may have a curvature of 0.36 mm. -1 ~0.13mm -1 It may have a rear curvature. The center thickness of the lens may be 0.70 mm to 0.90 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.40 mm to 0.60 mm.

[0080] One embodiment of a lens having a diopter indication power of 25D to 35D and a refractive index of approximately 1.50 to 1.60 has a power shape factor of -0.7 to -0.95. In this case, the first surface is 0.01 mm -1~0.082mm -1 The front surface may have a curvature of -0.179 mm. -1 ~-0.081mm -1 It may have a rear curvature. The center thickness of the lens may be 0.55 mm to 0.90 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.35 mm to 0.60 mm.

[0081] Lens set A set of lenses may be provided, comprising at least one lens having a power-shape coefficient of -1 or less as defined above, and / or at least one lens having a power-shape coefficient of -1 or more as defined above. The set of lenses may comprise a series of lenses. The diopter of each lens in the series may differ from that of the other lenses in the series by at least 0.25D. For example, the series of lenses may comprise five lenses having diopter values ​​of 17.5D, 17.75D, 18D, 18.25D, and 18.5D. The diopter of each lens in the series may differ from that of the other lenses in the series by 0.5D, 1D, 2D, 3D, 4D, or 5D. Lenses in a set of lenses may have a power below the transition point power or a power above the transition point power. The lens body of an IOL having a power above the transition point power may be formed differently from the lens body of an IOL having a power below the transition point power. The transition point power is the indicated power corresponding to an IOL with a shape factor of -1. For example, referring to Figure 4, the transition point power may be 23D, 24D, or 25D for lenses with a refractive index of 1.40 to 1.50. Referring to Figure 5, the transition point power may be 23D, 25D, or 28D for lenses with a refractive index of 1.50 to 1.60.

[0082] The provision of a set of lenses enables the correction of peripheral vision for prescriptions having a dioptric power above the transition point power, in addition to the correction of peripheral vision for prescriptions requiring a dioptric power below the transition point power. Thus, embodiments of the lens set of the present invention enable the correction of peripheral vision across the entire range of possible prescriptions. Advantageously, the set may provide a range of lenses that can be selected by a user to match the selected lens to the patient's dioptric power requirements.

[0083] According to regions 610 and 620 of FIG. 6, an embodiment of a lens set having a refractive index of 1.40 to 1.50 has at least one first lens having a diopter display power of 17 diopters to 23 diopters with a power shape coefficient of -1.0 or less and -2.5 or more, and at least one second lens having a diopter display power of 23 diopters to 30 diopters with a power shape coefficient of -0.2 or less and -1 or more. Within these ranges, the front curvature and the rear curvature can be refined to produce an easily predictable variation of the shape coefficient over the entire range. This stability increases the ease with which the lens can correct peripheral vision while optimizing axial vision.

[0084] For at least one first lens, the first surface can have a front curvature of -0.77 mm -1 to 0.00 mm -1 The second surface can have a rear curvature of -0.355 mm -1 to -0.130 mm -1 The central thickness can be 0.62 mm to 1.0 mm. A front haptic can be connected to the lens body to hold the lens in place after implantation, and the IOL can exhibit a bolt height of 0.34 mm to 0.65 mm.

[0085] For at least one second lens, the first surface can have a front curvature of 0 mm -1 to 0.120 mm -1 The second surface can have a rear curvature of -0.367 mm -1 to -0.130 mm-1 It may have a posterior curvature. The central thickness may be 0.62 mm to 1.0 mm. The anterior haptic is connected to the lens body and can hold the implanted lens in a fixed position. The IOL may exhibit a bolt height of 0.34 mm to 0.65 mm.

[0086] According to regions 710 and 720 of FIG. 7, a second embodiment of the lens set comprises a lens having a refractive index of 1.50 to 1.60. The lens set includes at least one first lens having a diopter display power of 20D to 28D with a power shape factor of -1 to -3, and at least one second lens having a diopter display power of 23D to 35D with a power shape factor of -0.5 to -1. Within these ranges, the anterior and posterior curvatures can be refined to produce an easily predictable variation of the shape factor over the entire range. This stability enables excellent predictability when producing lenses that can correct peripheral vision while optimizing axial vision.

[0087] For at least one first lens in the second embodiment of the lens set, the first surface may have an anterior curvature of -0.022 mm -1 to 0.00 mm -1 The second surface may have a posterior curvature of -0.170 mm -1 to -0.081 mm -1 The central thickness may be 0.45 mm to 1.0 mm. The anterior haptic is connected to the lens body and can hold the implanted lens in a fixed position. The IOL may exhibit a bolt height of 0.30 mm to 0.65 mm.

[0088] For at least one second lens in the second embodiment of the lens set, the first surface may have an anterior curvature of 0.00 mm -1 to 0.082 mm -1 The second surface may have a posterior curvature of -0.179 mm -1 to -0.081 mm -1It may have a rear curvature. The central thickness may be 0.45 mm to 1.0 mm. The front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.30 mm to 0.65 mm.

[0089] A third embodiment of the lens set comprises lenses having a refractive index of 1.40 to 1.50. The lens set comprises at least one first lens having a diopter indication power of 18D to 22D with a power-shape factor of -1.1 to -2.0, and at least one second lens having a diopter indication power of 24D to 29D with a power-shape factor of -0.3 to -0.8. The lenses in this lens set include a partial range of indication powers and shape factors that can be selected to optimize the structural elements of the IOL to result in minimized off-axial astigmatism and maximized on-axial visual acuity with a 20-degree eccentricity, thereby improving peripheral vision.

[0090] At least one first lens of the third embodiment of the lens set has a front curvature of -0.071 mm -1 ~-0.00mm -1 It may have a first surface having -0.355mm. The second surface may have -0.355mm -1 ~-0.134mm -1 It may have a rear curvature. The center thickness of the lens may be 0.7 mm to 0.9 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.40 mm to 0.60 mm.

[0091] At least one second lens of the third embodiment of the lens set is 0mm -1 ~0.12mm -1 It may have a first surface which may have a front curvature of 0.36 mm. The second surface may have a front curvature of 0.36 mm. -1 ~0.13mm -1It may have a rear curvature. The center thickness of the second lens may be 0.7 mm to 0.9 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.40 mm to 0.60 mm.

[0092] A fourth embodiment of the lens set comprises lenses having a refractive index of 1.50 to 1.60. The lens set comprises at least one first lens having a diopter indication power of 20D to 27D with a power-shape factor of -1.0 to -2.4, and at least one second lens having a diopter indication power of 25D to 35D with a power-shape factor of -0.7 to -0.95. The lenses in this lens set include a sub-range of indication power and shape factor that can be selected to optimize the structural elements of the IOL to result in minimized off-axis astigmatism and maximized on-axis visual acuity with a 20-degree eccentricity, thereby improving peripheral vision.

[0093] In the first lens of the fourth embodiment, the first surface is -0.022 mm -1 ~-0.00mm -1 The front surface may have a curvature of -0.170 mm. -1 ~-0.084mm -1 It may have a rear curvature. The center thickness of the first lens may be 0.55 mm to 0.90 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.35 mm to 0.60 mm.

[0094] For at least one second lens of the fourth embodiment, the first surface is 0.01 mm -1 ~0.082mm -1 The front surface may have a curvature of -0.179 mm. -1 ~-0.081mm -1It may have a rear curvature. The center thickness of the lens may be 0.55 mm to 0.90 mm. A front haptic can be connected to the lens body to hold the implanted lens in place, and the IOL may have a vault height of 0.35 mm to 0.60 mm.

[0095] A fifth embodiment of the lens set comprises at least one first lens having a refractive index of 1.40 to 1.50 and a diopter indication power of 17D to 23D, along with a power-shape factor of -1.0 or less and -2.5 or greater; and at least one second lens having a refractive index of 1.50 to 1.60 and a diopter indication power of 23D to 35D, along with a power-shape factor of -0.5 to -1. Within these ranges, the front and rear curvatures can be refined to produce easily predictable variations in the shape factor across the entire range. This stability allows for excellent predictability when producing lenses that can correct peripheral vision while optimizing axial vision.

[0096] A sixth embodiment of the lens set comprises at least one first lens having a refractive index of 1.50–1.60, a diopter power of 20D–28D, and a power-shape factor of -1–-3, and at least one second lens having a refractive index of 1.40–1.50 and a diopter power of 23–30 diopters, along with a power-shape factor of -0.2 or less and -1 or more. Within these ranges, the front and rear curvatures can be refined to produce easily predictable variations in the shape factor across the entire range. This stability allows for excellent predictability when producing lenses that can correct peripheral vision while optimizing axial vision.

[0097] A seventh embodiment of the lens set comprises at least one first lens having a refractive index of 1.50 to 1.60 and a diopter indication power of 20D to 27D, along with a power-shape factor of -1.0 to -2.4, and at least one second lens having a refractive index of 1.40 to 1.50 and a diopter indication power of 24D to 29D, along with a power-shape factor of -0.3 to -0.8. The lenses in this lens set include a partial range of indication powers and shape factors that can be selected to optimize the structural elements of the IOL to result in minimized off-axis astigmatism and maximized on-axis visual acuity with a 20-degree eccentricity, thereby improving peripheral vision.

[0098] An eighth embodiment of the lens set comprises at least one first lens having a refractive index of 1.40 to 1.50 and a diopter indication power of 18D to 22D, along with a power-shape factor of -1.1 to -2.0, and at least one second lens having a refractive index of 1.50 to 1.60 and a diopter indication power of 25D to 35D, along with a power-shape factor of -0.7 to -0.95. The lenses in this lens set include a partial range of indication powers and shape factors that can be selected to optimize the structural elements of the IOL to result in minimized off-axis astigmatism and maximized on-axis visual acuity with a 20-degree eccentricity, thereby improving peripheral vision.

[0099] This disclosure further illustrates, using a power-shape coefficient range, how the lenses according to this disclosure may have a range of structural values ​​that ensure appropriate function and improved peripheral vision when implanted in a patient.

[0100] It is further conceivable that any of the lenses disclosed herein may also correct mean corneal spherical aberration as defined in ISO 11979-2 2014, eye model #2.

[0101] Industrial applications A method for designing a set of intraocular lenses for improved peripheral vision may be provided. The method may include providing an IOL having a power that reduces optical errors in the image produced at a peripheral retinal position of the patient's eye, positioned at a certain distance from the fovea. The IOL may be provided for increments of 0.25D in the range of 17D to 35D. As the indicated power of the lens increases from 17D to 35D, the power-shape factor increases from -3.0 to -0.2. For indicated powers corresponding to shape factors below the transition point power, the IOL comprises a first lens body having a power-shape factor of -1 or less, according to the embodiments considered above. For indicated powers corresponding to shape factors above the transition point power, the IOL comprises a second lens body having a power-shape factor of -1 or more, according to the embodiments considered above. Each IOL may have a blur parameter of less than 1.8D.

[0102] Other methods for designing lens sets are also conceivable within the scope of this disclosure.

[0103] The intraocular lens according to this disclosure may also utilize complex surfaces, such as Zernike surfaces and toroidal surfaces, in addition to other variable heterogeneous surface structures for the anterior and posterior surfaces of the lens body. In one non-limiting embodiment of the IOL, the first surface has an anterior radius and indicates the anterior power, and the second surface has a posterior radius and indicates the posterior power. At least one of the first or second surface may be a complex surface. The intraocular lens indicates a power-shape coefficient for a constant plano-convex power-shape coefficient and corresponding to a diopter-expressed power, the power-shape coefficient including a first power value calculated using the anterior and posterior radii, and a second power value calculated using the anterior and posterior powers. The first and second power values ​​may have equal or different values ​​for their respective diopter-expressed powers. At least one of the first or second surface has a refractive profile. Thus, complex surfaces may use variable anterior and posterior radius values ​​and variable first power values. A complex surface may further include an effective power-shape factor having only a second power factor calculated using the anterior and posterior powers. In embodiments, at least one of the first and second surfaces includes a toric surface. The power-shape factor of the intraocular lens has a toric surface having an average of power meridians calculated over distinctly different portions of the intraocular lens surface. In additional embodiments, an additional power may be added to the diopter-indicated power, and the power-shape factor remains equal to a second power value calculated using the basic anterior and posterior powers.

[0104] In another embodiment of the intraocular lens according to this disclosure, the IOL has a first surface having an anterior radius and indicating an anterior power, and a second surface having a posterior radius and indicating a posterior power. Optionally, at least one of the first or second surface is a complex surface having multiple curvatures across the surface. As with other lenses described above, the intraocular lens exhibits a power-shape coefficient for a constant plano-convex power-shape coefficient and corresponding to a diopter-measured power. The power-shape coefficient may have a first power value calculated using the anterior and posterior radii, and a second power value calculated using the anterior and posterior powers. The first and second power values ​​may have different values ​​for their respective diopter-measured powers. In the non-limiting lenses of this disclosure, the complex surface may have variable anterior and posterior radius values, and a variable first power value. Complex surfaces may further include an effective power-shape factor calculated using only a second power factor, which is then calculated using the overall anterior power and the overall posterior power, where the overall power takes into account different radii of curvature. In some embodiments, at least one of the first or second surfaces includes a toric surface (i.e., exhibiting an annular or toroidal shape over at least a portion of the surface). The power-shape factor of an intraocular lens having a toric surface may be the average of power meridians calculated over distinctly different portions of the intraocular lens surface. In some cases, the IOLs of this disclosure have an additional power in addition to the indicated power, and the power-shape factor remains equal to a second power value calculated using the basic anterior power and the basic posterior power.

[0105] In some circumstances, this disclosure describes relationships between optical components with respect to position or with respect to operating parameters that are equivalent to one another. These descriptions are not limiting to this disclosure but are provided for illustrative purposes only. In fact, where this disclosure uses numerical values ​​for dimensions or ranges, all numerical values ​​should be understood as “approximately” or “approximately equal,” and these terms should be given the broadest plain meaning in relation to the art. In some embodiments, a particular optical parameter may be “approximately” or “approximately equal” to a particular value if the magnitudes of the optical parameters differ from each other by an amount within a range selected from 0 to 5 percent of the larger value. Ranges in this disclosure include endpoints unless otherwise specified or indicated by the context of the range.

[0106] In addition to the background considerations described above, this disclosure incorporates certain contextual information regarding exemplary structures for IOLs, the optical effects of these structures on patient visual acuity, and the environment in which IOLs are successfully used. As expected, numerous diagnostic procedures occur before a physician prescribes an IOL for a patient. Measurements of the patient's eye may be performed in a clinical setting by an optometrist, ophthalmologist, or other medical or optical specialist. Measurements may be performed via subjective refraction, objective refraction, tomography, or a combination of these or other measurement methods. Optical aberrations of the patient's eye may also be determined.

[0107] The range of a patient's vision can also be determined. For example, a patient's ability to focus on nearby objects (presbyopia) can be measured and determined. The range of add power for ophthalmic lenses can also be determined.

[0108] Measurements of the patient's eye may be included in an ophthalmic lens prescription, including the characteristics of at least one optical element intended to address the optical aberrations of the patient's eye, as well as characteristics that address the patient's visual range (e.g., the amount of add power and the number of focal points provided by the optical element).

[0109] Ophthalmic lens prescriptions can be used to manufacture optical elements for ophthalmic lenses. The refractive profile of an optical element can be determined based on the ophthalmic lens prescription to correct optical aberrations in the patient's eye. Such refractive profiles can be applied to the optical element, whether on a surface including a diffraction profile or on an opposite optical surface. The diffraction profile can also be determined to provide a desired distribution of the add power of the optical element.

[0110] The determination of one or more refractive or diffraction profiles and the fabrication of optical elements may be performed remotely by an optometrist, ophthalmologist, or other medical or optical professional who performed the measurements of the patient's eye, or may be performed at the same clinical facility as such an individual. If performed remotely, the fabricated optical elements may be delivered to the optometrist, ophthalmologist, or other medical or optical professional for provision to the patient. For intraocular lenses, the fabricated optical elements may be provided for implantation in the patient's eye. Fabricated optical elements may be manufactured according to embodiments of this disclosure.

[0111] The manufactured optical elements may be custom optical elements specifically manufactured for the patient's eye, or they may be manufactured in a manufacturing assembly and then selected by an optometrist, ophthalmologist, or other medical or optical professional for supply to the patient, which may include implantation into the patient's eye.

[0112] Finally, while aspects of this specification are emphasized by reference to specific embodiments, it should be understood that those skilled in the art will readily grasp that these disclosed embodiments are merely illustrative of the principles of the subject matter disclosed herein. Therefore, it should be understood that the disclosed subject matter is not in any way limited to the specific methodologies, protocols, and / or reagents described herein. Accordingly, various modifications or changes to the disclosed subject matter, or alternative configurations, can be made in accordance with the teachings herein without departing from the spirit of this specification. Finally, the terms used herein are intended solely to describe specific embodiments and are not intended to limit the scope of the systems, apparatus, and methods disclosed herein, as defined solely by the claims. Therefore, the systems, apparatus, and methods are not limited to those precisely illustrated and described.

[0113] Certain embodiments of the System, Apparatus, and Method, including the best modes known to the inventors for performing the System, Apparatus, and Method, are described herein. Naturally, variations of these described embodiments will be apparent to those skilled in the art by reading the preceding description. The inventors expect that those skilled in the art will appropriately adopt such variations, and they intend that the System, Apparatus, and Method may be practiced in ways other than those specifically described herein. Accordingly, the System, Apparatus, and Method include all modifications and equivalents of the subject matter enumerated in the claims appended herein, as permitted by applicable law. Furthermore, any combination of the above embodiments in all possible variations thereof is incorporated into the System, Apparatus, and Method unless otherwise indicated herein or unless it is clearly inconsistent with the context.

[0114] Any alternative embodiments, components, or groupings of processes of the System, Apparatus, and Method shall not be construed as limitations. Elements of each group may be referred to individually or in any combination with elements of other groups disclosed herein and may be claimed. It is anticipated that one or more elements of a group may be included in or excluded from a group for convenience and / or patentability reasons. Where any such inclusion or exclusion occurs, this specification shall be deemed to include the modified groups and thus satisfy the written specification of all Markush groups used in the appended claims.

[0115] In connection with the description of this system, apparatus, and method (in particular with the claims below), the terms “a,” “an,” and “the,” as well as similar demonstrative pronouns, shall be construed to refer to both singular and plural forms unless otherwise indicated herein or unless clearly contradicted by the context. All methods described herein may be carried out in any preferred order unless otherwise indicated herein or unless clearly contradicted by the context. The use of any examples or illustrative language provided herein (e.g., “etc.”) is intended solely to clarify the system, apparatus, and method and shall not limit the scope of the system, apparatus, and method unless otherwise asserted. Nothing in this specification should be construed to indicate any unclaimed component that is essential to the practice of the system, apparatus, and method.

[0116] All patents, patent publications, and other publications referenced and identified herein are incorporated herein individually and expressly by reference in their entirety for the purpose of describing and disclosing compositions and methodologies described in such publications, which may be used, for example, in connection with the System, Apparatus, and Method. These publications are provided solely for their disclosure prior to the filing date of this application. In this regard, the inventors should not be construed as acknowledging that they have no right to retroactively access such disclosures for the sake of prior art or for any other reason. All statements or expressions relating to the dates or contents of these documents, based on information available to the applicant, do not constitute any acknowledgment of the accuracy of the dates or contents of these documents. [Examples]

[0117] Various aspects of the subject matter described herein are described in the following numbered examples, which may or may not be claimed. 1. An intraocular lens, It has a lens body, and the lens body is, An intraocular lens having a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 17D to 23D including both ends, and a power shape factor of -1.0 or less and -2.5 or greater. 2. An intraocular lens according to Example 1, wherein the lens includes a diopter power of 18D to 22D, including both ends. 3. An intraocular lens according to Example 2, wherein the power-shape coefficient is -1.1 or less and -2.0 or more. 4. The intraocular lens according to Example 1, wherein the lens includes a central thickness of 0.62 mm to 1.0 mm. 5. An intraocular lens according to Example 2 or 3, wherein the lens includes a central thickness of 0.70 mm to 0.90 mm. 6. An intraocular lens according to Example 1 or 4, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.34 mm to 0.65 mm. 7. An intraocular lens according to any one of Examples 2, 3, or 5, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.40 mm to 0.60 mm. 8. The lens has a -0.077mm offset. -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.355 mm -1 Exceeding -0.130mm -1 An intraocular lens according to any one of Examples 1, 4, or 6, comprising a second surface having a posterior curvature of less than 1. 9. The lens has a -0.071mm offset. -1 Exceeding 0.00 mm -1 Front curvature less than -0.355mm -1 Exceeding -0.134mm -1 An intraocular lens according to any one of Examples 2, 3, 5, or 7, comprising a first surface having a posterior curvature of less than . 10. Intraocular lens, It has a lens body, and the lens body is, An intraocular lens having a refractive index of 1.50 to 1.60 including both ends, a diopter indication power of 20D to 28D including both ends, and a power shape factor of -1.0 or less and -3 or greater. 11. An intraocular lens according to Example 10, wherein the lens includes diopter-indicated powers of 20D to 27D. 12. An intraocular lens according to Example 11, wherein the power-shape coefficient is -1.0 or less and -2.4 or more. 13. An intraocular lens according to Example 10, wherein the lens includes a central thickness of 0.45 mm to 1.0 mm. 14. An intraocular lens according to Example 11 or 12, wherein the lens includes a central thickness of 0.55 mm to 0.90 mm. 15. An intraocular lens according to Example 10 or 13, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.30 mm to 0.65 mm. 16. An intraocular lens according to Example 11, 12, or 14, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.35 mm to 0.60 mm. 17. An intraocular lens according to Example 1 or 10, wherein the first surface of the lens is concave and the second surface is convex with respect to the optical axis of the lens. 18. The intraocular lens according to Example 17, wherein the concave surface includes a frontal radius of curvature of the concave surface that is larger than the posterior radius of curvature of the convex surface. 19. The lens has a -0.022mm offset. -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.170 mm -1 Exceeding -0.081mm -1 An intraocular lens according to any one of Examples 10, 13, or 15, comprising a second surface having a posterior curvature of less than 1. 20. The lens has a -0.022mm offset. -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.170 mm -1 Exceeding -0.084mm -1 An intraocular lens according to any one of Examples 11, 12, 14, or 16, comprising a second surface having a posterior curvature of less than . 21. Intraocular lens, It has a lens body, and the lens body is, An intraocular lens having a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 23D to 30D including both ends, and a power shape factor of -0.2 or less and -1 or greater. 22. The intraocular lens according to Example 21, wherein the lens includes a diopter indication power of 24D to 29D, including both ends. 23. An intraocular lens according to Example 22, wherein the power-shape coefficient is -0.3 or less and -0.8 or more. 24. An intraocular lens according to Example 21, wherein the lens includes a central thickness of 0.62 mm to 1.0 mm. 25. An intraocular lens according to Example 22 or 23, wherein the lens includes a central thickness of 0.70 mm to 0.90 mm. 26. An intraocular lens according to Example 21 or 24, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.34 mm to 0.65 mm. 27. An intraocular lens according to any one of Examples 22, 23, or 25, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.40 mm to 0.60 mm. 28. The lens is 0mm -1 Exceeding 0.120 mm -1 A first surface having a front curvature of less than -0.367 mm -1 Exceeding -0.130mm -1 An intraocular lens according to any one of Examples 21, 24, or 26, comprising a second surface having a posterior curvature of less than . 29. The lens is 0mm -1 Exceeding 0.12 mm -1 A first surface having a front curvature of less than -0.36 mm -1 Exceeding -0.130mm -1 An intraocular lens according to any one of Examples 22, 23, 25, or 27, comprising a second surface having a posterior curvature of less than 1. 30. Intraocular lens, It has a lens body, and the lens body is, An intraocular lens having a refractive index of 1.50 to 1.60 including both ends, a diopter indication power of 23D to 35D including both ends, and a power shape factor of -0.2 or less and -1 or greater. 31. An intraocular lens as described in Example 30, wherein the diopter indication power is 25D to 35D, including both ends. 32. The intraocular lens according to Example 31, wherein the power-shape coefficient is -0.40 or less and -0.95 or more. 33. An intraocular lens according to Example 30, wherein the lens includes a central thickness of 0.45 mm to 1.0 mm. 34. An intraocular lens according to Example 31 or 32, wherein the lens includes a central thickness of 0.55 mm to 0.90 mm. 35. An intraocular lens according to Example 30 or 33, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.30 mm to 0.65 mm. 36. An intraocular lens according to any one of Examples 31, 32, or 34, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.35 mm to 0.60 mm. 37. The lens is 0.00mm -1 exceeding 0.082 mm -1 A first surface having a front curvature of less than -0.179 mm -1 Exceeding -0.081mm -1 An intraocular lens according to any one of Examples 30, 33, or 35, comprising a second surface having a posterior curvature of less than 1. 38. The lens is 0.01mm -1 exceeding 0.082 mm -1 A first surface having a front curvature of less than -0.179 mm -1 Exceeding -0.081mm -1 An intraocular lens according to any one of Examples 31, 32, 34, or 36, comprising a second surface having a posterior curvature of less than 1. 39. An intraocular lens according to any one of Examples 1, 10, 21, or 30, wherein the power-shape factor is calculated using the paraaxially defined radii of curvature of the first and second surfaces. 40. The frequency shape coefficient is given by the formula

[0118]

number

[0119]

number

[0120] [Implementation Method] (1) Intraocular lens, The lens body comprises, An intraocular lens having a refractive index of 1.40 to 1.50 including both ends, a diopter label power of 17D to 23D including both ends, and a power shape factor of -1.0 or less and -2.5 or greater. (2) The intraocular lens according to Embodiment 1, wherein the lens includes a diopter power of 18D to 22D, including both ends. (3) The intraocular lens according to Embodiment 2, wherein the power-shape coefficient is -1.1 or less and -2.0 or more. (4) The intraocular lens according to Embodiment 1, wherein the lens includes a central thickness of 0.62 mm to 1.0 mm. (5) The intraocular lens according to Embodiment 2, wherein the lens includes a central thickness of 0.70 mm to 0.90 mm.

[0121] (6) The intraocular lens according to Embodiment 1, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.34 mm to 0.65 mm. (7) The intraocular lens according to Embodiment 2, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.40 mm to 0.60 mm. (8) The lens is -0.077mm -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.355 mm -1 Exceeding -0.130mm -1 An intraocular lens according to Embodiment 1, comprising a second surface having a posterior curvature of less than 1. (9) The lens is -0.071mm -1 Exceeding 0.00 mm -1 Front curvature less than -0.355mm -1 Exceeding -0.134mm -1 An intraocular lens according to Embodiment 2, comprising a first surface having a posterior curvature of less than 50%. (10) Intraocular lens, Including the lens body, the lens body is An intraocular lens having a refractive index of 1.50 to 1.60 including both ends, a diopter indication power of 20D to 28D including both ends, and a power shape factor of -1.0 or less and -3 or greater.

[0122] (11) The intraocular lens according to Embodiment 10, wherein the lens includes a diopter power of 20D to 27D. (12) The intraocular lens according to Embodiment 11, wherein the power-shape coefficient is -1.0 or less and -2.4 or more. (13) The intraocular lens according to Embodiment 10, wherein the lens includes a central thickness of 0.45 mm to 1.0 mm. (14) The intraocular lens according to Embodiment 11, wherein the lens includes a central thickness of 0.55 mm to 0.90 mm. (15) The intraocular lens according to Embodiment 10, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.30 mm to 0.65 mm.

[0123] (16) The intraocular lens according to Embodiment 11, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.35 mm to 0.60 mm. (17) The intraocular lens according to Embodiment 1 or 10, wherein the first surface of the lens has a concave surface and the second surface has a convex surface with respect to the optical axis of the lens. (18) The intraocular lens according to Embodiment 17, wherein the concave surface includes a front surface curvature radius of the concave surface that is larger than the rear surface curvature radius of the convex surface. (19) The lens is -0.022mm -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.170 mm -1 Exceeding -0.081mm -1 An intraocular lens according to embodiment 10, comprising a second surface having a posterior curvature of less than 10. (20) The lens is -0.022mm -1 Exceeding 0.00 mm -1 A first surface having a front curvature of less than -0.170 mm -1 Exceeding -0.084mm -1 An intraocular lens according to embodiment 11, comprising a second surface having a posterior curvature of less than 1.

[0124] (21) Intraocular lens, The lens body comprises, An intraocular lens having a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 23D to 30D including both ends, and a power shape factor of -0.2 or less and -1 or greater. (22) The intraocular lens according to Embodiment 21, wherein the lens includes a diopter power of 24D to 29D, including both ends. (23) The intraocular lens according to Embodiment 22, wherein the power-shape coefficient is -0.3 or less and -0.8 or more. (24) The intraocular lens according to Embodiment 21, wherein the lens includes a central thickness of 0.62 mm to 1.0 mm. (25) The intraocular lens according to Embodiment 22, wherein the lens includes a central thickness of 0.70 mm to 0.90 mm.

[0125] (26) The intraocular lens according to Embodiment 21, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.34 mm to 0.65 mm. (27) The intraocular lens according to Embodiment 22, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.40 mm to 0.60 mm. (28) The lens is 0mm -1 Exceeding 0.120 mm -1 A first surface having a front curvature of less than -0.367 mm -1 Exceeding -0.130mm -1 An intraocular lens according to embodiment 21, comprising a second surface having a posterior curvature of less than 1. (29) The lens is 0mm -1 Exceeding 0.12 mm -1 A first surface having a front curvature of less than -0.36 mm -1 Exceeding -0.130mm -1 An intraocular lens according to embodiment 22, comprising a second surface having a posterior curvature of less than 50%. (30) Intraocular lens, The lens body comprises, An intraocular lens having a refractive index of 1.50 to 1.60 including both ends, a diopter indication power of 23D to 35D including both ends, and a power shape factor of -0.2 or less and -1 or greater.

[0126] (31) The intraocular lens according to embodiment 30, wherein the diopter indication power is 25D to 35D, including both ends. (32) The intraocular lens according to Embodiment 31, wherein the power-shape coefficient is -0.40 or less and -0.95 or more. (33) The intraocular lens according to Embodiment 30, wherein the lens includes a central thickness of 0.45 mm to 1.0 mm. (34) The intraocular lens according to Embodiment 31, wherein the lens includes a central thickness of 0.55 mm to 0.90 mm. (35) The intraocular lens according to Embodiment 30, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.30 mm to 0.65 mm.

[0127] (36) The intraocular lens according to Embodiment 31, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.35 mm to 0.60 mm. (37) The lens is 0.00 mm -1 exceeding 0.082 mm -1 A first surface having a front curvature of less than -0.179 mm -1 Exceeding -0.081mm -1 An intraocular lens according to embodiment 30, comprising a second surface having a posterior curvature of less than 1. (38) The lens is 0.01 mm -1 exceeding 0.082 mm -1 A first surface having a front curvature of less than -0.179 mm -1 Exceeding -0.081mm -1 An intraocular lens according to embodiment 31, comprising a second surface having a posterior curvature of less than 1. (39) An intraocular lens according to any one embodiment 1, 10, 21, or 30, wherein the power-shape coefficient is calculated using the paraaxially defined radii of curvature of the first surface and the second surface. (40) The frequency shape coefficient is given by the formula

number

[0128] (41) The intraocular lens according to any one of Embodiments 1, 10, 21, or 30, wherein the power-shape coefficient is calculated by ray tracing technology applied to the intraocular lens. (42) The intraocular lens according to embodiment 41, wherein the ray tracing technique includes utilizing a specific aperture diameter. (43) The intraocular lens according to Embodiment 41, wherein the ray tracing technique includes utilizing a specific aperture diameter, the best focal position, and the spherical aberration effect on the power-shape coefficient. (44) An intraocular lens according to any one of embodiments 1 to 43, having an MTF value of at least 0.7 for a 5 mm pupil at a spatial frequency of 50 cycles / mm in green light. (45) An intraocular lens according to any of Embodiments 1 to 44, wherein the intraocular lens corrects mean corneal spherical aberration as defined in ISO 11979-2 2014, eye model #2.

[0129] (46) An intraocular lens according to any one of embodiments 1 to 45, wherein the lens has an aspherical front surface, or the lens has an aspherical rear surface, or the lens has an aspherical rear surface and an aspherical front surface. (47) A set of intraocular lenses that improve peripheral vision, A first lens as described in any of Embodiments 1 to 20, A set comprising at least one second lens as described in any of embodiments 21 to 38. (48) The set of intraocular lenses according to Embodiment 47, wherein the at least one first lens comprises a series of lenses, the diopter power of each lens in the series differing by at least 0.25 diopters. (49) The set of intraocular lenses according to Embodiment 47, wherein the at least one second lens comprises a series of lenses, the diopter power of each lens in the series differing by at least 0.25 diopters. (50) A method for designing a set of intraocular lenses for improved peripheral vision, wherein as the indicated power of the lens increases from 17D to 35D, the power-shape factor increases from -2.5 to -0.2, and the method The invention includes providing an IOL having an optical power that reduces optical error in the image produced at a peripheral retinal position of the patient's eye located at a certain distance from the fovea, for each display power increment of at least 0.25 diopters, For display powers corresponding to a shape coefficient of -1 or less, the IOL comprises a lens as described in any of Embodiments 1 to 20. For display powers corresponding to a shape coefficient of -1 or greater, the IOL comprises a lens as described in any of embodiments 21 to 38. The blur parameter of each IOL is less than 1.8 diopters, and the said blur parameter is

number

Claims

1. It is an intraocular lens, The lens body comprises, An intraocular lens having a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 17D to 23D including both ends, and a power shape factor of -1.0 or less and -2.5 or greater.

2. The intraocular lens according to claim 1, wherein the lens includes a diopter power of 18D to 22D, including both ends.

3. The intraocular lens according to claim 2, wherein the power-shape coefficient is -1.1 or less and -2.0 or more.

4. The intraocular lens according to claim 1, wherein the lens includes a central thickness of 0.62 mm to 1.0 mm.

5. The intraocular lens according to claim 2, wherein the lens includes a central thickness of 0.70 mm to 0.90 mm.

6. The intraocular lens according to claim 1, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.34 mm to 0.65 mm.

7. The intraocular lens according to claim 2, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.40 mm to 0.60 mm.

8. The aforementioned lens has a -0.077 mm －１ Exceeding 0.00 mm －１ A first surface having a front curvature of less than -0.355 mm －１ Exceeding -0.130 mm －１ The intraocular lens according to claim 1, comprising a second surface having a posterior curvature of less than 1.

9. The aforementioned lens has a -0.071 mm －１ Exceeding 0.00 mm －１ Front curvature less than -0.355 mm －１ Exceeding -0.134 mm －１ The intraocular lens according to claim 2, comprising a first surface having a posterior curvature of less than 500.

10. It is an intraocular lens, Including the lens body, the lens body is An intraocular lens having a refractive index of 1.50 to 1.60 including both ends, a diopter indication power of 20D to 28D including both ends, and a power shape factor of -1.0 or less and -3 or greater.

11. The intraocular lens according to claim 10, wherein the lens includes a diopter power of 20D to 27D.

12. The intraocular lens according to claim 11, wherein the power-shape coefficient is -1.0 or less and -2.4 or more.

13. The intraocular lens according to claim 10, wherein the lens includes a central thickness of 0.45 mm to 1.0 mm.

14. The intraocular lens according to claim 11, wherein the lens includes a central thickness of 0.55 mm to 0.90 mm.

15. The intraocular lens according to claim 10, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.30 mm to 0.65 mm.

16. The intraocular lens according to claim 11, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.35 mm to 0.60 mm.

17. The intraocular lens according to claim 1, wherein the first surface of the lens has a concave surface and the second surface has a convex surface with respect to the optical axis of the lens.

18. The intraocular lens according to claim 17, wherein the concave surface includes a front surface curvature radius of the concave surface that is larger than the rear surface curvature radius of the convex surface.

19. The lens has a front surface curvature greater than -0.022 mm －１ and less than 0.00 mm －１ and a second surface having a rear surface curvature greater than -0.170 mm －１ and less than -0.081 mm －１ The intraocular lens according to claim 10, comprising:

20. The aforementioned lens has a -0.022 mm －１ Exceeding 0.00 mm －１ A first surface having a front curvature of less than -0.170 mm －１ Exceeding -0.084 mm －１ The intraocular lens according to claim 11, comprising a second surface having a posterior curvature of less than 1.

21. It is an intraocular lens, The lens body comprises, An intraocular lens having a refractive index of 1.40 to 1.50 including both ends, a diopter indication power of 23D to 30D including both ends, and a power shape coefficient of -0.2 or less and -1 or greater.

22. The intraocular lens according to claim 21, wherein the lens includes a diopter power of 24D to 29D, including both ends.

23. The intraocular lens according to claim 22, wherein the power-shape coefficient is -0.3 or less and -0.8 or more.

24. The intraocular lens according to claim 21, wherein the lens includes a central thickness of 0.62 mm to 1.0 mm.

25. The intraocular lens according to claim 22, wherein the lens includes a central thickness of 0.70 mm to 0.90 mm.

26. The intraocular lens according to claim 21, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.34 mm to 0.65 mm.

27. The intraocular lens according to claim 22, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.40 mm to 0.60 mm.

28. The aforementioned lens is 0 mm －１ exceeding and 0.120 mm －１ A first surface having a front curvature of less than -0.367 mm －１ Exceeding -0.130 mm －１ The intraocular lens according to claim 21, comprising a second surface having a posterior curvature of less than 1.

29. The aforementioned lens is 0 mm －１ exceeding 0.12 mm －１ A first surface having a front curvature of less than -0.36 mm －１ Exceeding -0.130 mm －１ The intraocular lens according to claim 22, comprising a second surface having a posterior curvature of less than 1.

30. It is an intraocular lens, The lens body comprises, An intraocular lens having a refractive index of 1.50 to 1.60 including both ends, a diopter indication power of 23D to 35D including both ends, and a power shape factor of -0.2 or less and -1 or greater.

31. The intraocular lens according to claim 30, wherein the diopter indication power is 25D to 35D, including both ends.

32. The intraocular lens according to claim 31, wherein the power-shape coefficient is -0.40 or less and -0.95 or more.

33. The intraocular lens according to claim 30, wherein the lens includes a central thickness of 0.45 mm to 1.0 mm.

34. The intraocular lens according to claim 31, wherein the lens includes a central thickness of 0.55 mm to 0.90 mm.

35. The intraocular lens according to claim 30, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.30 mm to 0.65 mm.

36. The intraocular lens according to claim 31, further comprising an anterior haptic connected to the lens body, wherein the lens includes a vault height of 0.35 mm to 0.60 mm.

37. The aforementioned lens is 0.00 mm －１ exceeding 0.082 mm －１ A first surface having a front curvature of less than -0.179 mm －１ Exceeding -0.081 mm －１ The intraocular lens according to claim 30, comprising a second surface having a posterior curvature of less than 1.

38. The aforementioned lens is 0.01 mm －１ exceeding 0.082 mm －１ A first surface having a front curvature of less than -0.179 mm －１ Exceeding -0.081 mm －１ The intraocular lens according to claim 31, comprising a second surface having a posterior curvature of less than 1.

39. The intraocular lens according to claim 1, wherein the power-shape coefficient is calculated using the paraaxially defined radii of curvature of the first surface and the second surface.

40. The aforementioned frequency shape coefficient is given by the formula [Math 1] It is calculated according to the formula, and in the formula, the frequency 前 However, the power of the front surface of the lens body is 後 The intraocular lens according to claim 1, wherein the power is posterior.

41. The intraocular lens according to claim 1, wherein the power-shape coefficient is calculated by ray tracing technology applied to the intraocular lens.

42. The intraocular lens according to claim 41, wherein the ray tracing technique includes utilizing a specific aperture diameter.

43. The intraocular lens according to claim 41, wherein the ray tracing technique includes utilizing a specific aperture diameter, the best focal position, and the spherical aberration effect on the power-shape coefficient.

44. The intraocular lens according to claim 1, having an MTF value of at least 0.7 for a 5 mm pupil at a spatial frequency of 50 cycles / mm in green light.

45. The intraocular lens according to claim 1, wherein the intraocular lens corrects mean corneal spherical aberration as defined in ISO 11979-2 2014, ocular model #2.

46. The intraocular lens according to any one of claims 1 to 45, wherein the lens has an aspherical front surface, or the lens has an aspherical rear surface, or the lens has an aspherical rear surface and an aspherical front surface.

47. A set of intraocular lenses that improve peripheral vision, A first lens according to any one of claims 1 to 20, A set comprising at least one second lens as described in any one of claims 21 to 38.

48. The set of intraocular lenses according to claim 47, wherein the at least one first lens comprises a series of lenses, the diopter power of each lens in the series differing by at least 0.25 diopters.

49. The set of intraocular lenses according to claim 47, wherein the at least one second lens comprises a series of lenses, the diopter power of each lens in the series differing by at least 0.25 diopters.

50. A method for designing a set of intraocular lenses for improved peripheral vision, wherein as the indicated power of the lens increases from 17D to 35D, the power-shape factor increases from -2.5 to -0.2, and the method is The invention includes providing an IOL having an optical power that reduces optical errors in the image generated at a peripheral retinal position of the patient's eye, positioned at a certain distance from the fovea, for each display power increment of at least 0.25 diopters. For display powers corresponding to a shape coefficient of -1 or less, the IOL comprises the lens described in any one of claims 1 to 20. For display powers corresponding to a shape coefficient of -1 or greater, the IOL comprises the lens described in any one of claims 21 to 38. The blur parameter of each IOL is less than 1.8 diopters, and the blur parameter is [Math 2] A method calculated according to the following.

Images