Method and composition for enhancing AMPK in mammals
Oral D-ribose supplementation, combined with exercise, activates AMPK and enhances metabolic pathways, improving energy levels and insulin sensitivity in mammals, addressing the need for lower dose effectiveness in healthy individuals.
Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- BIOENERGY INC
- Filing Date
- 2023-10-26
- Publication Date
- 2026-05-27
AI Technical Summary
Existing studies on D-ribose supplementation primarily focus on athletes or individuals with specific diseases, and the effectiveness of lower concentrations in healthy mammals for enhancing metabolic demands and modifying organelles through AMPK activation has not been demonstrated.
Oral administration of D-ribose at varying doses, combined with exercise, to activate AMPK and enhance metabolic pathways, including the AMP/ATP ratio, thereby increasing energy levels and improving insulin sensitivity.
D-ribose, even at lower doses, effectively increases AMPK and citrate synthase levels, enhances oxidative metabolism, decreases blood glucose without additional insulin, and improves antioxidant status, mimicking the health benefits of physical activity by increasing ATP levels in both exercising and sedentary mammals.
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