Systems and methods for peak searching and artificial tissue response, including for processing functional response waveforms.

Abstract

A system and method for processing functional response waveforms obtained from artificial tissue are described herein. In one exemplary embodiment, the system and method includes obtaining a first waveform, which includes the contraction and relaxation responses of the artificial tissue during a contraction-relaxation cycle. A model that independently parameterizes the growth of the contraction and relaxation responses is then fitted to the first waveform. A second waveform is then generated from the model fitted to the first waveform, such that the second waveform includes a noise-filtered representation of the first waveform. Feature values(s) can then be extracted from the second waveform, which can be used to develop artificial intelligence (AI) or, otherwise, for downstream tasks such as drug discovery and development, by performing noise filtering and enabling high-fidelity and large synthetic training datasets.

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