Orthogonal multimer proteins

Engineered multimeric proteins with CH1:CL electrostatic and FcγRIIIA(CD16a) binding variants address the challenge of indiscriminate pairing in antibody production, achieving stable and efficient assembly.

JP2026517745APending Publication Date: 2026-06-02XENCOR INC
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Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
XENCOR INC
Filing Date
2024-04-26
Publication Date
2026-06-02

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Abstract

A multimer protein that reduces the indiscriminate pairing of monomers of the multimer protein and / or promotes the proper pairing of monomers of the multimer protein, as well as a method of using such a multimer protein, is provided herein.
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