Compositions containing polynucleotides and polypeptides (amphiphilic substances) and methods for using the same
Compounds with immunostimulatory nucleic acid sequences and albumin-binding domains, along with polypeptides, enhance vaccine-induced immunity by forming specific configurations to stimulate robust and sustained immune responses.
JP2026519945APending Publication Date: 2026-06-19ELICIO THERAPEUTICS INC
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Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Applications
- Current Assignee / Owner
- ELICIO THERAPEUTICS INC
- Filing Date
- 2024-04-25
- Publication Date
- 2026-06-19
AI Technical Summary
Technical Problem
Many vaccines do not induce optimal immunity, necessitating the development of new compositions and methods to enhance immune responses.
Method used
Compounds comprising immunostimulatory nucleic acid sequences, albumin-binding domains, and polypeptides, or their pharmaceutically acceptable salts, are administered to induce an immune response by forming specific configurations such as end-binding or end-ligation, with optional linkers and reactive functional groups, to enhance antigen-specific immune responses.
Benefits of technology
These compounds effectively stimulate a strong, sustained immune response, providing long-term protection against infections by enhancing the immune response to antigens.
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Figure 2026519945000001_ABST
Abstract
Compounds comprising immunomodulatory (e.g., immunostimulatory or immunosuppressive) nucleic acid sequences, polypeptides, and albumin-binding domains, as well as pharmaceutically acceptable salts thereof, are disclosed herein. Furthermore, methods for inducing an immune response in a subject, and methods for inducing an immune response in a subject by administering such compounds, are disclosed herein.
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