Ophthalmic pharmaceutical composition, method for preparing the same, ophthalmic kit containing the same, and use

A biodegradable ophthalmic pharmaceutical composition for posterior ocular diseases enables easy, ergonomic injection and sustained drug release, addressing the complexity and discomfort of current treatments.

JP2026521802APending Publication Date: 2026-07-01SHENYANG XINGQI PHARM CO LTD

Patent Information

Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
SHENYANG XINGQI PHARM CO LTD
Filing Date
2024-07-03
Publication Date
2026-07-01

AI Technical Summary

Technical Problem

Current treatments for posterior ocular diseases require complex administration methods, such as surgery or dedicated devices, causing discomfort and increasing treatment costs, while existing implants either need removal or have short drug half-lives.

Method used

A biodegradable ophthalmic pharmaceutical composition that can be injected using a simple syringe, providing sustained release of active ingredients with a particle size ≤50 μm, ensuring easy administration and long-term efficacy without the need for complex devices.

Benefits of technology

The composition allows for convenient, ergonomic injection and sustained release of drugs within the eye, maintaining therapeutic levels for extended periods with improved patient compliance and reduced risk of infection.

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Abstract

An ophthalmic pharmaceutical composition comprising or consisting of 1 part by weight of an active pharmaceutical ingredient, 0.95 to 1.25 parts by weight of a liquid substrate, and 0.35 to 0.45 parts by weight of a solid substrate, wherein the particle size of the active pharmaceutical ingredient is D 90 An ophthalmic pharmaceutical composition satisfying ≤50 μm, a method for preparing the same, an ophthalmic kit containing the ophthalmic pharmaceutical composition, and the use of the ophthalmic pharmaceutical composition or ophthalmic kit in the preparation of a pharmaceutical for the prevention and / or treatment of an ophthalmic disease.
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