User terminal, control method and computer program

Abstract

To perform more appropriate dispensing according to individual differences regarding medications.SOLUTION: One aspect of the present invention is a user terminal including: a communication unit that communicates with other devices via a network; an output unit that outputs information to a user; and a control unit that acquires information about medications that are prescribed to the user and require caution in use for the user and outputs the information about the medications requiring caution in use to the user via the output unit.SELECTED DRAWING: Figure 1

Description

[Technical field]

[0001] The present invention relates to a user terminal , regulation Method and computer programs Regarding. [Background technology]

[0002] Conventionally, when medicines are provided to patients, pharmacists at a dispensing facility dispense the medicines according to a prescription issued by a doctor and provide the medicines to the patient. In order to increase the convenience of dispensing medicines based on prescriptions, applications related to medicines have been provided. Some of these applications include an electronic implementation of a medicine notebook (e.g., Non-Patent Document 1). By using such applications, users can easily manage information about the medicines prescribed to them. Furthermore, pharmacists can dispense medicines more appropriately based on the information related to the medicine notebook recorded by the application. [Prior art documents] [Non-patent literature]

[0003] [Non-Patent Document 1] "Medicine Handbook," Japan Pharmaceutical Association, [online], [searched February 10, 2020], Internet<URL:http: / / www-eokusuri.nichiyaku.or.jp / index.html> Summary of the Invention [Problem to be solved by the invention]

[0004] However, even for the same drug, there are individual differences in the effectiveness of the drug, the likelihood of side effects, etc. Conventionally, it has been difficult to dispense medicines according to such individual differences. In view of the above circumstances, an object of the present invention is to provide a technique that enables more appropriate dispensing in accordance with individual differences regarding medicines. [Means for solving the problem]

[0005] One aspect of the present invention is an information providing device that includes a communication unit that communicates with other devices via a network, and a control unit that determines which of the drugs prescribed to the user require caution when used by the user based on information indicating drugs that the user requires caution when using, which is obtained based on information about the user's genes, and information indicating drugs prescribed to the user, and provides information indicating the determination result to other devices.

[0006] One aspect of the present invention is an information management device that includes a communication unit that communicates with other devices via a network, a memory unit that stores user genetic information, which is information about a user's genes, and caution drug information, which is obtained based on the user genetic information and indicates drugs that the user should use with caution, and a control unit that provides the caution drug information to other devices.

[0007] One aspect of the present invention is a user terminal that includes a communication unit that communicates with other devices via a network, an output unit that outputs information to a user, and a control unit that acquires information regarding medications prescribed for the user that require caution when used by the user, and outputs the information regarding the medications that require caution when used to the user via the output unit.

[0008] One aspect of the present invention is an acquisition method having the steps of acquiring the drugs used by a user, the effects on the user's body after the user used the drugs, and the time in order to estimate interactions between multiple drugs used by the user, and performing at least one of a process of transmitting the acquired drugs, the effects, and the time to another device and a process of storing them in a storage device.

[0009] One aspect of the present invention is a user interface having a drug input field that accepts input of information indicating a drug used by a user, an effect input field that accepts input of information indicating effects on the user's body achieved after use by the user, and a transmission decision field that accepts an instruction to transmit the information input by the user.

[0010] One aspect of the present invention is a database having a memory unit that stores, in association with each other, the effects on the user's body that occurred after the user used the drug, and time, in order to estimate interactions between multiple drugs used by the user.

[0011] One aspect of the present invention is an information providing method having the steps of: determining which of the drugs prescribed to a user require caution when taking the drug(s) based on information indicating which drugs the user requires caution when taking, the information being obtained based on genetic information about the user, and information indicating which drugs have been prescribed to the user; and providing information indicating the determination result to another device.

[0012] One aspect of the present invention is a control method comprising the steps of acquiring information regarding drugs and medications prescribed to a user that require careful use by the user, and outputting to the user the information regarding the drugs and medications that require careful use. Effect of the Invention

[0013] The present invention makes it possible to carry out more appropriate preparation of medicines according to individual differences. [Brief description of the drawings]

[0014] [Figure 1] 1 is a schematic block diagram showing a system configuration of an information providing system 100 according to the present invention. [Diagram 2] 1 is a schematic diagram showing an example of the configuration of a drug information database 10. FIG. [Diagram 3] FIG. 13 is a diagram showing a specific example of drug information. [Figure 4] 1 is a schematic diagram showing an example of the configuration of a user genetic information management device 20. FIG. [Diagram 5] FIG. 13 is a diagram showing a specific example of caution drug information. [Figure 6] FIG. 13 is a diagram showing a specific example of genetic related information. [Figure 7] 2 is a schematic diagram showing an example of the configuration of an information providing server 30. FIG. [Figure 8] FIG. 11 is a diagram showing a specific example of feedback information. [Figure 9] FIG. 2 is a schematic diagram showing an example of the configuration of a user terminal 40. [Figure 10] FIG. 13 is a diagram showing an example of an output mode of prescription information. [Figure 11] FIG. 13 is a diagram showing an example of an output form in which genetic-related information is displayed. [Figure 12] FIG. 13 is a diagram showing an example of an output form in which genetic-related information is displayed. [Figure 13] FIG. 13 is a diagram showing an example of an output mode of prescription information. [Figure 14] FIG. 13 is a diagram showing an example of an output form in which genetic-related information is displayed. [Figure 15] FIG. 13 is a diagram showing an example of an output mode of prescription information. [Figure 16] FIG. 13 is a diagram showing an example of an output form in which genetic-related information is displayed. [Figure 17] FIG. 13 is a diagram showing an example of a usage reminder screen. [Figure 18] FIG. 13 is a diagram showing a specific example of a questionnaire screen. [Figure 19] 2 is a sequence chart showing a specific example of the flow of operations of the information providing system 100. [Figure 20] 2 is a sequence chart showing a specific example of the flow of operations of the information providing system 100. [Figure 21] 2 is a sequence chart showing a specific example of the flow of operations of the information providing system 100. [Figure 22]FIG. 11 is a schematic block diagram showing a system configuration of a modified example of the information providing system 100 of the present invention. [Diagram 23] 13 is a sequence chart showing a specific example of the flow of operations of a modified example of the information providing system 100. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0015] First, the main points of this embodiment will be described. It is known that there is a correlation between the individual differences in drug use, i.e., the effectiveness of a specific drug and the side effects caused by a specific drug, and human genetic polymorphisms. Based on this correlation, this embodiment uses the user's genetic polymorphism to dispense appropriate drugs according to the individual differences in drug use.

[0016] Hereinafter, specific configuration examples of the present invention will be described with reference to the drawings. FIG. 1 is a schematic block diagram showing the system configuration of an information providing system 100 of the present invention. The information providing system 100 is a system for providing users or drug-related parties with information on drugs (hereinafter referred to as "drug-related information") that takes into account individual differences such as the effectiveness of the drug and the likelihood of side effects. A drug-related party is a person who decides the type and amount of drug to be used for a user. The action of being used for a user may be administering the drug to the user, or the user taking the drug, or sticking the drug on the user's body, or applying the drug to the user's body, or injecting the drug into the user. Any action may be taken as long as the drug is given to the user's body. The drug used may be a medicine that is taken or may be a drug that is applied or injected, or may be any drug given to the user. A drug-related party is, for example, a doctor or a person at a dispensing facility (for example, a pharmacist). The effectiveness of a drug indicates the degree of change in the user's condition due to the administration of a predetermined unit amount of a predetermined drug. The effectiveness of a drug may be defined as information indicating the degree to which the effect is difficult to appear even if the usual dose is used. If a drug is broken down quickly by metabolic enzymes produced by genetic polymorphism, the administered drug will be less effective. The drug-related information may indicate the generic name or trade name of a specific drug, or may indicate information indicating a collection of drugs with the same function (such as multiple trade names of drugs with the same ingredient or trade names of generic drugs), or may indicate the names of the ingredients.

[0017] The information providing system 100 includes a drug information database 10, a user genetic information management device 20, an information providing server 30, a user terminal 40, and a dispensing terminal 50. The drug information database 10, the user genetic information management device 20, the information providing server 30, the user terminal 40, and the dispensing terminal 50 are communicatively connected via a network 90. ​​The network 90 may be a network using wireless communication or a network using wired communication. The network 90 may be configured by combining a plurality of networks.

[0018] The drug information database 10 stores information indicating the relationship between each drug and a gene (hereinafter referred to as "drug information"). The user genetic information management device 20 stores information regarding genes (hereinafter referred to as "user genetic information") for each user. The user genetic information management device 20 stores drug-related information for each user. The drug-related information is obtained based on the drug information and the user genetic information. The drug-related information includes caution drug information and genetic-related information. The caution drug information is information indicating drugs that require caution for use by each user. The caution drug information may include, for example, information on drugs that require caution for side effects or the like beyond a predetermined standard, may include information on drugs that may have an effect below a predetermined standard even if used, or may include information on side effects that may occur when used. The genetic-related information includes information on genes that are the cause of drugs that require caution in addition to the caution drug information. The standard of caution may be appropriately set in the information providing system 100 according to the degree of caution determined by the relationship between the user and the drug, the social situation, and the like. For example, the standard of caution may be determined according to various criteria, such as a threshold for an allergic reaction, or the percentage of users who have used the product that experience a certain level of drowsiness.

[0019] The user genetic information management device 20 normally provides the information providing server 30 with caution drug information. The information providing server 30 provides the user terminal 40 and the dispensing terminal 50 with information on drugs that require caution for each individual user based on the caution drug information. For example, if a prescription issued to a user contains a drug that requires caution for that user, an alert may be issued. Such caution drug information does not include information on an individual's genes. Therefore, it is possible to provide information on drugs that is tailored to individual differences while keeping the individual's genetic information confidential.

[0020] Furthermore, when a predetermined condition (hereinafter referred to as "permission condition") indicating that the user's permission has been obtained is satisfied, the user genetic information management device 20 provides part or all of the genetic-related information to other devices (for example, the user terminal 40 and the dispensing terminal 50). The genetic-related information includes information on the user's genes as more detailed information than the caution drug information. The genetic-related information to be provided is permitted partially or entirely by the user. For example, the user may permit only the genetic-related information on a specific disease to be provided. For example, the user may permit only the genetic-related information on a specific drug to be provided. Such genetic information is provided only when the permission condition is satisfied, so that it can be handled confidentially as the user's personal information. In addition, when the permission condition is satisfied, the information is provided to other devices, so that the pharmacist can obtain the genetic-related information and perform more appropriate dispensing. Details of the information provision system 100 will be described below.

[0021] 2 is a schematic diagram showing an example of the configuration of the drug information database 10. The drug information database 10 is configured using an information processing device such as a personal computer or a server device. The drug information database 10 includes a communication unit 11, a storage unit 12, and a control unit 13.

[0022] The communication unit 11 is a communication device. The communication unit 11 may be configured as, for example, a network interface. The communication unit 11 performs data communication with other devices via the network 90 in response to the control of the control unit 13. The communication unit 11 may be a device that performs wireless communication or a device that performs wired communication.

[0023] The storage unit 12 is configured using a storage device such as a magnetic hard disk device or a semiconductor storage device. The storage unit 12 stores data used by the control unit 13. The storage unit 12 stores, for example, drug information. FIG. 3 is a diagram showing a specific example of drug information. The drug information includes certain genetic information and information about a drug that may affect metabolism when the genetic information is possessed. The genetic information associated with a drug or an effect may be information indicating a genetic polymorphism, information indicating a genotype (a set of genes), or information about an expressed gene. The drug information includes, for example, information about a drug that may affect metabolism when a mutation such as a deletion occurs in a certain gene. A genetic polymorphism is an individual difference in the sequence of DNA constituting a gene, and the individual difference affects the metabolism of the drug.

[0024] For example, the drug phenytoin is sometimes used in brain-damaged patients to prevent symptomatic epilepsy seizures. If the blood concentration of phenytoin becomes too high, it may cause side effects such as dizziness and coma. Therefore, it is necessary to prevent the blood concentration of phenytoin from becoming too high. On the other hand, CYP2C9, a molecular species of CYP, is involved in the metabolism of phenytoin, and in individuals with mutations in CYP2C9, phenytoin may not be metabolized well. That is, in individuals with mutations in CYP2C9, there is a high possibility that an increase in the area under the blood concentration-time curve and an extension of the half-life are observed. Therefore, caution is required when prescribing phenytoin to such individuals (users). Drug information includes information on drug metabolism that occurs in response to gene polymorphisms in this way. Such drug information is obtained, for example, based on papers on drugs and genes, experimental results, etc. Drug information is updated as appropriate according to new papers, new experimental results, etc.

[0025] The control unit 13 is configured using a processor such as a CPU (Central Processing Unit) and a memory. The control unit 13 functions as a communication control unit 131 and a database control unit 132 by the processor executing a program. All or part of the functions of the control unit 13 may be realized using hardware such as an ASIC (Application Specific Integrated Circuit), a PLD (Programmable Logic Device), or an FPGA (Field Programmable Gate Array). The above program may be recorded on a computer-readable recording medium. The computer-readable recording medium is, for example, a portable medium such as a flexible disk, a magneto-optical disk, a ROM, a CD-ROM, or a semiconductor storage device (for example, an SSD: Solid State Drive), or a storage device such as a hard disk or a semiconductor storage device built into a computer system. The above program may be transmitted via an electric communication line.

[0026] The communication control unit 131 controls communication with other devices via the communication unit 11. The database control unit 132 updates the drug information stored in the storage unit 12. For example, when new drug information is obtained from another device, the database control unit 132 updates the drug information based on the obtained information. When the provision of drug information is requested by another device, the database control unit 132 provides part or all of the drug information stored in the storage unit 12. The database control unit 132 may be configured to provide part or all of the drug information stored in the storage unit 12 only to a specific authenticated device.

[0027] 4 is a schematic diagram showing an example of the configuration of a user genetic information management device 20. The user genetic information management device 20 is configured using an information processing device such as a personal computer or a server device. It is preferable that the user genetic information management device 20 is a device managed by an organization that is requested by users to analyze genetic information, or an organization authorized to manage genetic information. The user genetic information management device 20 includes a communication unit 21, a memory unit 22, and a control unit 23.

[0028] The communication unit 21 is a communication device. The communication unit 21 may be configured as, for example, a network interface. The communication unit 21 performs data communication with other devices via the network 90 in accordance with the control of the control unit 23. The communication unit 21 may be a device that performs wireless communication or a device that performs wired communication.

[0029] The storage unit 22 is configured using a storage device such as a magnetic hard disk device or a semiconductor storage device. The storage unit 22 stores data used by the control unit 23. The storage unit 22 stores, for example, user genetic information and drug-related information. The storage unit 22 may further store feedback information.

[0030] The user genetic information includes genetic information for each user. The user may have blood drawn at a hospital or the like, and the genetic information for each user may be acquired by analyzing the drawn blood. For example, an analysis may be performed using a microarray or the like to detect differences in a type of DNA sequence that differs by only one base, which is mainly called SNP (Single Nucleotide Polymorphism). Such an analysis may be performed on the entire genome of the user, or on a specific region of the genome. Such an analysis may be performed, for example, by a genotyping company. The user genetic information includes information on gene polymorphisms possessed by each user. The user genetic information may include information on a genotype (a set of genes) and expressed genes. The user genetic information may be registered in association with a user ID assigned to each user. The user ID used in the user genetic information management device 20 and the user ID used in the information provision server 30 may be different user IDs. In this case, a table in which each user ID assigned to the same user is associated with each other may be registered in the storage unit 22. Additionally, user IDs assigned to the same user may be associated with each other, for example, by using other identification information (eg, insurance policy number) assigned to the user.

[0031] As described above, drug-related information includes caution drug information and genetic information. FIG. 5 is a diagram showing a specific example of caution drug information. The caution drug information has information indicating, for each user, drugs that require caution in handling beyond a predetermined standard. The user ID in FIG. 5 is identification information that uniquely identifies each user. For example, the example in FIG. 5 indicates that a user with user ID "A1" needs to be careful with phenytoin and warfarin.

[0032] FIG. 6 is a diagram showing a specific example of genetic information. The genetic information has, for each user, information indicating drugs that require caution in handling beyond a predetermined standard, and information indicating gene polymorphisms that cause the drug to require caution. The user ID in FIG. 6 is identification information that uniquely identifies each user. For example, the example in FIG. 6 shows that a user with user ID "A1" needs to be careful with phenytoin, and that this is due to the user having a variant of the gene polymorphism of the gene CYP2C9 that is involved in the metabolic activity of phenytoin.

[0033] The control unit 23 is configured using a processor such as a CPU and a memory. The control unit 23 functions as a communication control unit 231, a database control unit 232, and an information providing unit 233 by the processor executing a program. All or part of the functions of the control unit 23 may be realized using hardware such as an ASIC, a PLD, or an FPGA. The above program may be recorded on a computer-readable recording medium. The computer-readable recording medium is, for example, a portable medium such as a flexible disk, a magneto-optical disk, a ROM, a CD-ROM, or a semiconductor storage device (e.g., SSD), or a storage device such as a hard disk or a semiconductor storage device built into a computer system. The above program may be transmitted via an electric communication line.

[0034] The communication control unit 231 controls communication with other devices via the communication unit 21. The database control unit 232 updates the drug-related information stored in the storage unit 22. For example, when new genetic information of a user is obtained, the database control unit 232 records the obtained genetic information in the storage unit 32. When new genetic information of a user is obtained, the database control unit 232 generates drug-related information (cautionary drug information and genetic-related information) based on the obtained genetic information and the drug information recorded in the drug information database 10. For example, the database control unit 232 collates the newly obtained genetic information of the user with the information of genetic polymorphisms in the drug information one by one to see if they match, and when there is information of a matching genetic polymorphism, the database control unit 232 may obtain information on the drug and the effect associated with the genetic polymorphism from the drug information to generate drug-related information. The database control unit 232 records the generated drug-related information in the storage unit 22.

[0035] The information providing unit 233 provides the information server 30 with the caution drug information only for users who have obtained the primary consent in advance. Furthermore, for users who have obtained the primary consent in advance and have obtained the secondary consent thereafter, the information providing unit 233 provides the genetic-related information to a predetermined other device. In this case, the permission condition is that the primary consent and the secondary consent have been obtained. The primary consent may be obtained electronically, for example, when a predetermined application is installed on the user terminal 40, or may be obtained in a predetermined document. Once the primary consent is obtained, it may be maintained as having been obtained until the user explicitly requests to revoke it. Information indicating whether the primary consent has been obtained for each user may be recorded in the storage unit 22.

[0036] The secondary consent may be required each time a request for provision of genetic-related information is made from the user. In other words, even if the secondary consent has been obtained once, if a request for provision of genetic-related information is made again, the information providing unit 233 may request the secondary consent from the user each time. This configuration makes it possible to appropriately protect information related to the user's genes.

[0037] FIG. 7 is a schematic diagram showing an example of the configuration of the information providing server 30. The information providing server 30 is configured using an information processing device such as a personal computer or a server device. The information providing server 30 does not need to be managed by an organization requested by a user to analyze genetic information, or an organization authorized to manage genetic information. The information providing server 30 may be a device managed by an organization that provides a service of providing information on prescribed medicines to users. The information providing server 30 includes a communication unit 31, a memory unit 32, and a control unit 33.

[0038] The communication unit 31 is a communication device. The communication unit 31 may be configured as, for example, a network interface. The communication unit 31 performs data communication with other devices via the network 90 according to the control of the control unit 33. The communication unit 31 may be a device that performs wireless communication or a device that performs wired communication.

[0039] The storage unit 32 is configured using a storage device such as a magnetic hard disk device or a semiconductor storage device. The storage unit 32 stores data used by the control unit 33. The storage unit 32 stores, for example, drug warning information provided by the user genetic information management device 20. The storage unit 32 may store, for example, information about drugs prescribed in the past for each user (information about drug prescription history: for example, information recorded in a medicine notebook). Such drug information includes, for example, the type of drug, product name, quantity, and usage method.

[0040] The control unit 33 is configured using a processor such as a CPU and a memory. The control unit 33 functions as a communication control unit 331, a database control unit 332, a medicine information providing unit 333, and a feedback information providing unit 334 by the processor executing a program. All or part of the functions of the control unit 33 may be realized using hardware such as ASIC, PLD, or FPGA. The above program may be recorded in a computer-readable recording medium. The computer-readable recording medium is, for example, a portable medium such as a flexible disk, a magneto-optical disk, a ROM, a CD-ROM, or a semiconductor storage device (e.g., SSD), or a storage device such as a hard disk or a semiconductor storage device built into a computer system. The above program may be transmitted via an electric communication line.

[0041] The communication control unit 331 controls communication with other devices via the communication unit 31. The database control unit 332 updates the caution drug information stored in the storage unit 32. For example, the database control unit 332 may inquire of the user genetic information management device 20 at a predetermined timing about the presence or absence of updated information, and if there is updated information, obtain the updated information of the caution drug information and record it in the storage unit 32.

[0042] The drug information providing unit 333 manages information on the prescription history of drugs recorded for each user. When the drug information providing unit 333 acquires information on a newly prescribed drug from the user terminal 40, it registers the acquired information in the prescription history information of the drug in the storage unit 32. The drug information providing unit 333 determines whether the newly prescribed drugs include a drug included in the caution drug information for the user. If a drug included in the caution drug information has been prescribed, the drug information providing unit 333 transmits information indicating a warning (alert) about the drug to the user terminal 40 or the dispensing terminal 50. When the drug information providing unit 333 receives a prescription history request including a user ID from the user terminal 40, it reads out prescription history information registered in the storage unit 32 in association with the received user ID, and transmits the information to the user terminal 40.

[0043] When the feedback information providing unit 334 acquires the feedback information, it provides the acquired feedback information to another device. The feedback information providing unit 334 may provide the feedback information to, for example, the user genetic information management device 20. The feedback information is information provided by a user who has used a prescribed drug. The feedback information may be acquired to estimate interactions between a plurality of drugs used by the user. The feedback information is information about what the user felt after using the drug, changes in physical condition, and the like. The feedback information may be quantitative information (for example, information that can be acquired by a sensor such as heart rate, ECG (electrocardiogram), and pulse, and changes in a predetermined component of blood). The feedback information may be any information that indicates changes in the user's body caused by using the drug. The feedback information may further include the following information: Information indicating the drug used and the timing (for example, date and time) at which the drug was used. The time required from the use of the drug until the change in the user's physical condition. The time during which the change in the user's physical condition occurred (duration of the effect). Information indicating the presence or absence of side effects. Information indicating the presence or absence of a tendency to recover from symptoms. Information indicating foods and beverages that the user ingested within a predetermined time before and after taking the drug. Information indicating the food and beverage ingested by the user and the timing of ingestion (e.g., date and time). For example, by acquiring information indicating the food and beverage ingested by the user, it becomes possible to estimate the interaction between the medicine used by the user and the food and beverage ingested by the user. The feedback information may be input by the user to the user terminal 40, for example, and transmitted from the user terminal 40 to the information providing server 30 via the network 90. ​​Each value of the feedback information may be directly input by the user to the user terminal 40, or may be input by the user selecting from predefined options. The feedback information providing unit 334 may record the acquired feedback information in the memory unit 32.

[0044] 8 is a diagram showing a specific example of feedback information. The feedback information includes, for example, the genetic polymorphism related to the user providing the feedback, the drug used, the amount used, the date and time of use, and the user's impressions at the time of use (usage notes). Here, one of the purposes of acquiring feedback information will be explained. Side effects, effects, and how the drug works for a single drug are often accumulated as know-how from pharmaceutical company experiments or doctors and pharmacists. However, it is assumed that there is very little information accumulated about side effects, effects, and how the drug works when multiple drugs are administered simultaneously or within a time period when they may have an interaction, compared to single drugs. This is especially true when multiple drugs are administered by different pharmaceutical companies. Therefore, by accumulating and managing such feedback information, it is possible to accumulate drug interactions that work for each genotype. It may also be accumulated as interactions without considering the genotype.

[0045] 9 is a schematic diagram showing a configuration example of a user terminal 40. The user terminal 40 is configured using an information processing device such as a personal computer, a smartphone, a mobile phone, a portable game console, a wearable computer, etc. The user terminal 40 includes a communication unit 41, an input unit 42, an output unit 43, a storage unit 44, and a control unit 45.

[0046] The communication unit 41 is a communication device. The communication unit 41 may be configured as, for example, a network interface. The communication unit 41 performs data communication with other devices via the network 90 in response to the control of the control unit 45. The communication unit 41 may be a device that performs wireless communication or a device that performs wired communication.

[0047] The input unit 42 is configured using existing input devices such as a keyboard, a pointing device (mouse, tablet, etc.), buttons, a touch panel, etc. The input unit 42 is operated by a user when inputting a user's instruction to the user terminal 40. The input unit 42 may be an interface for connecting the input device to the user terminal 40. In this case, the input unit 42 inputs an input signal generated in the input device in response to a user's input to the user terminal 40. The input unit 42 may be configured using a microphone and a voice recognition device. In this case, the input unit 42 performs voice recognition on a word spoken by the user, and inputs character string information of the recognition result to the user terminal 40. The input unit 42 may be configured in any manner as long as it is configured to input a user's instruction to the user terminal 40.

[0048] The output unit 43 is configured using an output device, and outputs data to the user of the user terminal 40. The output device may be configured using, for example, a device that outputs images and characters to a screen. For example, the output device may be configured using a CRT (Cathode Ray Tube), a liquid crystal display, an organic EL (Electro-Luminescent) display, or the like. The output device may also be configured using a device that converts characters into voice and outputs the voice. In this case, the output device may be configured using a voice synthesizer and a voice output device (speaker). The output unit 43 may be an interface for connecting the output device to the user terminal 40.

[0049] The storage unit 44 is configured using a storage device such as a magnetic hard disk device or a semiconductor storage device. The storage unit 44 stores data used by the control unit 45. The storage unit 44 may store data of a predetermined application installed in the user terminal 40, for example.

[0050] The control unit 45 is configured using a processor such as a CPU and a memory. The control unit 45 functions as a communication control unit 451, a prescription information control unit 452, a genetic-related information control unit 453, and a feedback information control unit 454 by the processor executing a program. All or part of the functions of the control unit 45 may be realized using hardware such as ASIC, PLD, or FPGA. The above program may be recorded in a computer-readable recording medium. The computer-readable recording medium is, for example, a portable medium such as a flexible disk, a magneto-optical disk, a ROM, a CD-ROM, or a semiconductor storage device (e.g., SSD), or a storage device such as a hard disk or a semiconductor storage device built into a computer system. The above program may be transmitted via an electric communication line.

[0051] The communication control unit 451 controls communication between the communication unit 41 and other devices. The prescription information control unit 452 manages information on medicines newly prescribed to the user and information on medicines previously prescribed to the user. The process of acquiring information on medicines newly prescribed to the user and the process of acquiring information on medicines previously prescribed to the user will be described below.

[0052] The prescription information control unit 452 acquires, for example, information on a medicine newly prescribed to the user (such as type, product name, quantity, and usage method) and transmits it to the information providing server 30 together with the user ID. The information on the prescribed medicine may be input, for example, by the user operating the input unit 42, or may be input by acquiring encoded information such as a barcode printed on a prescription or the like. In this case, the encoded information such as the barcode may be information in which the information on the prescribed medicine itself is encoded, or may be information in which information (such as a URL) for accessing a server or the like that stores information on the prescribed medicine and acquiring the information is encoded. The encoded information such as the barcode is acquired, for example, by a device such as a barcode reader or an imaging device provided in the user terminal 40. The prescription information control unit 452 acquires information on the medicine newly prescribed to the user based on the encoded information such as the barcode.

[0053] The prescription information control unit 452 accesses the information providing server 30 to obtain information on drugs prescribed to the user in the past (information on the drug prescription history). For example, the prescription information control unit 452 transmits a prescription history request including a user ID to the information providing server 30. Upon receiving the prescription history request, the information providing server 30 transmits information indicating the prescription history for a predetermined period registered in association with the user ID to the user terminal 40. The prescription information control unit 452 outputs the obtained information from the output unit 43.

[0054] In response to a user operation, the genetics-related information control unit 453 requests genetics-related information from the user genetic information management device 20. Upon receiving genetics-related information from the user genetic information management device 20, the genetics-related information control unit 453 outputs the received genetics-related information from the output unit 43.

[0055] The feedback information control unit 454 requests the user to input feedback information. Such a request may be made, for example, by outputting predetermined information from the output unit 43. For example, the request to input feedback information may be made by displaying a screen on which feedback information can be input on the image display device (output unit 43). For example, the request to input feedback information may be made by displaying a screen on which feedback information can be input on the image display device (output unit 43) and outputting a voice prompting the user to input feedback information from the speaker (output unit 43). The request may be made in any manner. When feedback information is input by the user, the feedback information control unit 454 transmits the input feedback information to another device.

[0056] If the feedback information does not include information related to the user's genes, the feedback information may be transmitted to the information providing server 30. In this case, the feedback information may be transmitted together with a user ID indicating the user. A device (e.g., the user genetic information management device 20) that acquires the feedback information via the information providing server 30 may record the feedback information in association with the user's genetic information based on the user ID. By performing such processing, it becomes possible to link and manage the genetic information and the feedback information in the user genetic information management device 20 while keeping the genetic information, which is personal information, secret from the information providing server 30.

[0057] If the feedback information includes information regarding the user's genes, the feedback information may not be sent to the information providing server 30, but may be sent to a specific device that manages genetic information, such as a user genetic information management device 20.

[0058] 10 to 18 are diagrams showing examples of outputs from output unit 43 of user terminal 40. FIG. FIG. 10 is a diagram showing an example of the output mode of prescription information. As shown in FIG. 10, the drug information providing unit 333 of the user terminal 40 may display on a display the name of each prescribed drug (drug name), information indicating the presence or absence of an alert regarding the drug, and, if an alert is issued, an operation object for outputting information related to the gene that is the basis of the alert. Operation of the operation object indicates that secondary consent has been obtained by the user. In FIG. 10, the operation object is a character string that reads "display". A hyperlink is attached to this character string, and a request for genetic-related information may be transmitted to a predetermined destination of the hyperlink by operation by the user. In this case, it is preferable that the user genetic information management device 20 is set as the destination of the hyperlink.

[0059] When the user clicks on the character string "display", the user terminal 40 transmits a request including the user ID and the name or identifier of the drug for which the alert is issued to the user genetic information management device 20. When the user genetic information management device 20 receives the request, it transmits a response including genetic-related information. The response may include information for displaying the user interface of the user genetic information management device 20 on the browser. FIG. 11 is a diagram showing a specific example of a user interface displayed on the browser of the user terminal 40. As shown in FIG. 11, the browser of the user terminal 40 functions as the user interface of the user genetic information management device 20, so that subsequent user operations can be processed on the user genetic information management device 20. The user interface displayed on the browser of the user terminal 40 may display, for example, values ​​indicating the associated gene polymorphisms, drugs, and effects. Such a display may be, for example, a display showing a table of drug information as shown in FIG. 3.

[0060] Fig. 12 is a diagram showing another example of an output mode in which genetically-related information is displayed. Fig. 12 shows another example of a screen after the character string "display" is operated in Fig. 10. In the example of Fig. 12, genetically-related information is displayed in the place where the character string "display" (operation target) was displayed.

[0061] Fig. 13 is a diagram showing an example of an output mode of prescription information. In Fig. 13, in addition to the prescription information shown in Fig. 10, a display frame for displaying genetic-related information is further displayed.

[0062] FIG. 14 is a diagram showing an example of an output mode in which genetically-related information is displayed. FIG. 14 shows an example of a screen after the character string "display" in FIG. 13 is operated. The genetically-related information is displayed inside the display frame of the genetically-related information that was set in advance, not in the place where the character string "display" (operation object) was displayed. Also, in FIG. 14, the operation object of the character string "do not display" is displayed in the place where the character string "display" (operation object) was displayed in FIG. 13. When this operation object is operated, the genetically-related information control unit 453 controls so that the genetically-related information displayed in the display frame of the genetically-related information is not displayed. For example, control may be performed so that the screen transitions again to the screen shown in FIG. 13.

[0063] FIG. 15 is a diagram showing an example of the output mode of prescription information. As shown in FIG. 15, the drug information providing unit 333 of the user terminal 40 may display the name of each prescribed drug (drug name) and information indicating the presence or absence of an alert regarding the drug in a display frame of prescription information based on the acquired information regarding the prescription. In addition, when an alert is issued, an operation object for outputting information related to the gene that is the basis of the alert may be displayed in a display frame of genetic-related information provided in advance. In the example of FIG. 15, the operation object is a button including a character string "display". In response to the user operating this button, the genetic-related information control unit 453 requests the user genetic information management device 20 to transmit genetic-related information.

[0064] FIG. 16 is a diagram showing an example of an output mode in which genetic-related information is displayed. FIG. 16 shows an example of a screen after the button "display" in FIG. 15 is operated. In the place where the button "display" (operation target) was displayed, the encoded information of genetic-related information is displayed as genetic-related information. In FIG. 16, a two-dimensional code is displayed as a specific example of encoded information. For example, when the dispensing terminal 50 used in the dispensing facility 501 is operated and the two-dimensional code is decoded, the genetic information of the user is output in the dispensing terminal 50. If the encoded information is information obtained by encoding the genetic-related information itself, the dispensing terminal 50 can immediately display the genetic information on the display by decoding the encoded information. The encoded information may be information in which information (e.g., a URL) for accessing a server or the like (e.g., the user genetic information management device 20) that accumulates genetic-related information and acquiring the information is encoded. In this case, the dispensing terminal 50 may acquire the genetic information of the user by accessing another device based on the information obtained by decoding, and display the acquired genetic information on the display.

[0065] FIG. 17 is a diagram showing an example of a usage reminder screen. The prescription information control unit 452 determines the timing at which the user should use the drug based on information (particularly the usage method) about the currently prescribed drug. For example, if the usage method is defined as after meals in the morning and in the evening, the prescription information control unit 452 displays the usage reminder screen at a timing after a predetermined time has elapsed from the breakfast time and dinner time set in advance as a default or individually by the user. As shown in FIG. 17, the usage reminder screen may display characters or images (for example, a character string saying "It's time to take medicine") indicating that it is time to use the drug. Furthermore, an operation object may be displayed as a button to indicate to the user terminal 40 that the user will use the drug. In the example of FIG. 17, a button containing the characters "use" is displayed as the operation object. When the user operates the operation object, the prescription information control unit 452 records that the user has used the drug at that timing.

[0066] The feedback information control unit 454 may display a questionnaire screen (feedback information input screen) after the use reminder screen is displayed. FIG. 18 is a diagram showing a specific example of the questionnaire screen. The questionnaire screen includes at least characters and images that prompt the user to input predetermined feedback information. In the example of FIG. 18, three options of the user's state after use are displayed as feedback information. Each option may be displayed in association with an image for input such as a check box. The user inputs the feedback information on the questionnaire screen. The feedback information control unit 454 acquires the feedback information input by the user via the questionnaire screen. Note that in FIG. 18, information indicating the drug used by the user (drug name) and information indicating the amount of the drug used (amount used) are displayed on the screen in advance. However, these pieces of information may also be input in response to an operation by the user. Also, in FIG. 18, the date and time when the drug was used by the user is described as a usage memo, but such a date and time may be directly input by the user, may be acquired by the feedback information providing unit 454 as the date and time when the screen of FIG. 18 is displayed by the user, or may be acquired as the date and time when the "Use" button of FIG. 17 is operated.

[0067] 19 is a sequence chart showing a specific example of the flow of operations of the information providing system 100. When the user genetic information management device 20 acquires new genetic information of a user (step S101), it determines whether or not primary consent has been given for the user whose genetic information has been acquired. If primary consent has not been given (step S102-NO), the processing of the user genetic information management device 20 ends, and then the information providing server 30 and the user terminal 40 perform the processing from step S105 onwards.

[0068] On the other hand, if the primary consent has been given (step S102-YES), the user genetic information management device 20 generates caution drug information for the target user (step S103). Then, the user genetic information management device 20 transmits the caution drug information for the target user to the information server 30 (step S104).

[0069] When the information providing server 30 receives the caution drug information, it records the caution drug information in the storage unit 32. After that, when the prescription information is acquired (step S105), the information providing server 30 judges whether or not the medicine defined in the caution drug information is included in the medicine included in the prescription information (step S106). If the medicine defined in the caution drug information is included in the medicine included in the prescription information (step S106-YES), the information providing server 30 generates prescription information to which alert information is added for the medicine (steps S107 and S108). On the other hand, if the medicine defined in the caution drug information is not included in the medicine included in the prescription information (step S106-NO), the information providing server 30 generates prescription information to which alert information is not added (step S108). After that, the information providing server 30 transmits the generated prescription information to the user terminal 40 (step S109).

[0070] When the user terminal 40 receives the prescription information from the information providing server 30, it outputs the received prescription information. For example, the user terminal 40 displays the prescription information on a display, which is one aspect of the output unit 43 (step S110).

[0071] FIG. 20 is a sequence chart showing a specific example of the flow of the operation of the information providing system 100. FIG. 20 particularly shows the flow of the process after step S110 in FIG. 19. Prescription information is displayed on the user terminal 40 until an operation indicating secondary consent is performed (step S201-NO). Although not shown, when an operation indicating the end of displaying the prescription information is performed, the display of the prescription information may be ended. When an operation indicating secondary consent is performed on the user terminal 40 (step S201-YES), the user terminal 40 requests genetic-related information from the user genetic information management device 20.

[0072] When the user genetic information management device 20 receives a genetic-related information request indicating that secondary consent has been given from the user terminal 40, it generates genetic-related information for the user. Then, the user genetic information management device 20 transmits the generated genetic-related information to the user terminal 40 (step S203). When the user terminal 40 receives the genetic-related information, it outputs the received genetic-related information. For example, the user terminal 40 displays the genetic-related information on a display, which is one aspect of the output unit 43 (step S204).

[0073] FIG. 21 is a sequence chart showing a specific example of the flow of the operation of the information providing system 100. FIG. 21 shows a flow of processing particularly related to feedback information. When an operation indicating input of feedback information is performed on the user terminal 40 (step S301), the feedback information providing unit 454 displays a feedback information input screen on the user terminal 40 (step 302). When a value is input in each input field provided on the feedback information input screen, the feedback information control unit 454 accepts the input value. The input of the value may be performed by direct input of the value, may be performed by selecting from among options provided in advance, or may be input in other modes. After that, when an instruction to transmit the feedback information is given by the user (step S304-YES), the feedback information control unit 454 generates feedback information including the information input by the user up to that point, and transmits it to a predetermined other device (step S305). In the example of FIG. 21, the feedback information control unit 454 transmits the feedback information to the user genetic information management device 20.

[0074] The information providing system 100 configured in this way makes it possible to dispense medicines more appropriately according to individual differences in medicines. Specifically, it is as follows. The information providing system 100 determines medicines that require caution for each individual based on the individual's genetic information, and provides the medicines to the information providing server 30 as caution medicine information. The information providing server 30 determines whether the medicines included in a new prescription issued to a user include medicines that require caution for each individual. If such medicines are included, an alert is issued to the user regarding the medicine. Therefore, the user can consult a pharmacist or doctor about how to use the medicine, paying attention to medicines that require caution due to individual differences based on genes, even for medicines that do not require special caution for an average person.

[0075] Furthermore, in the information providing system 100, the caution drug information provided to the information providing server 30 does not include information on an individual's genes. Therefore, while achieving the above-mentioned effects, it is possible to keep genetic information as personal information confidential.

[0076] Furthermore, in the information provision system 100, if the user wishes to have prescriptions dispensed based on more detailed genetic information, the user can obtain genetic information (genetic-related information) as personal information by performing an operation related to secondary consent. In this case, the user can consult with a pharmacist or doctor about prescriptions and usage methods with more careful attention based on the user's own genes. Furthermore, in the above-mentioned process, genetic information can be obtained from the user genetic information management device 20 without going through the information provision server 30. Therefore, the genetic information as personal information can be kept secret while achieving the above-mentioned effects.

[0077] In addition, in the information providing system 100, a user who has used a prescribed drug can input information about what he or she felt after using the drug and changes in physical condition, etc., as feedback information to the user terminal 40. The feedback information is provided to other devices such as the user genetic information management device 20. Therefore, it is possible to develop better drugs based on changes in the physical condition of users who have actually used each drug. In consideration of such uses, it is more preferable that the feedback information includes the genetic information of the user. In addition, when a user uses multiple drugs, the drug used, the amount used, and the date and time of use may be fed back for each drug. In addition, the user's subjective symptoms and the date and time when they appeared may also be fed back. When multiple drugs are used, it is difficult for the user to determine whether the side effects are due to one of the drugs or a combination of drugs, but by acquiring the date and time of use of each drug and the date and time when the subjective symptoms appeared, it becomes possible for an expert to analyze the side effects.

[0078] (Modification) The functions implemented in each device may be implemented across multiple devices. For example, the user genetic information management device may be realized using multiple information processing devices. For example, the user genetic information management device 20 may be realized by dividing it into an information processing device that processes the database control unit 232 and an information processing device that processes the information provision unit 233.

[0079] FIG. 22 is a schematic block diagram showing a system configuration of a modified example of the information providing system 100 of the present invention. In the modified example of the information providing system 100, the information providing system 100 is provided with a doctor terminal 60. The doctor terminal 60 is installed in a medical facility 601. The doctor terminal 60 is an information processing device used by a doctor who prescribes medicines to a user. The doctor inputs a user ID of a user who is a patient to the doctor terminal 60. The user ID may be, for example, a user ID used in the medical facility 601. In this case, it is preferable that information that associates the user ID used in the medical facility 601 with the user ID used in the information providing server 30 is registered in any device such as the information providing server 30. The doctor inputs information on a medicine (hereinafter referred to as "prescription candidate information") that is to be prescribed to a user who is a patient to the doctor terminal 60. If the input prescription candidate information includes a medicine included in the user's caution medicine information indicated by the input user ID, the doctor terminal 60 outputs information on the medicine. Note that only the name of the medicine itself may be used as information on the medicine.

[0080] 23 is a sequence chart showing a specific example of the flow of operations of a modified example of the information providing system 100. A doctor inputs a user ID of a user who is a patient and prescription candidate information to the doctor terminal 60 (step S301). The doctor terminal 60 transmits the input prescription candidate information to the information providing server 30 (step s302).

[0081] The information providing server 30 determines whether or not the drugs included in the prescription candidate information include a drug defined in the caution drug information (step S303). If the drugs included in the prescription candidate information include a drug defined in the caution drug information, the information providing server 30 generates information (alert information) indicating that caution is required for that drug as a determination result. On the other hand, if the drugs included in the prescription candidate information do not include a drug defined in the caution drug information, the information providing server 30 generates information indicating that as a determination result. Thereafter, the information providing server 30 transmits the generated determination result to the doctor terminal 60 (step S304).

[0082] When the doctor terminal 60 receives the determination result from the information providing server 30, it outputs the received determination result. For example, the doctor terminal 60 displays the determination result on a display (step S305).

[0083] As another modification, the information providing server 30 may store, for each drug, a list indicating other drugs having the same medicinal effect. For example, for each drug, a list indicating other drugs that can be used as substitutes for that drug may be stored. When a newly prescribed drug or a drug in the prescription candidate information includes a drug in the user's caution drug information, the drug information providing unit 333 of the information providing server 30 searches for other drugs that are not included in the user's caution drug information and can be used as substitutes for the drug. Then, the drug information providing unit 333 of the information providing server 30 may transmit information indicating the search results (information indicating the searched other drugs) to another device (the user terminal 40, the dispensing terminal 50, or the doctor terminal 60).

[0084] Although an embodiment of the present invention has been described in detail above with reference to the drawings, the specific configuration is not limited to this embodiment, and designs that do not deviate from the gist of the present invention are also included. [Industrial Applicability]

[0085] The present invention is applicable to the technology of dispensing medicines. [Explanation of symbols]

[0086] 100...information providing system, 10...drug information database, 20...user genetic information management device, 30...information providing server, 40...user terminal, 50...prescription terminal, 90...network, 11...communication unit, 12...storage unit, 13...control unit, 131...communication control unit, 132...database control unit, 21...communication unit, 22...storage unit, 23...control unit, 231...communication control unit, 232...database control unit, 233...information providing unit, 31...communication unit, 32...storage unit, 33...control unit, 331...communication control unit, 332...database control unit, 333...drug information providing unit, 334...feedback information providing unit, 41...communication unit, 42...input unit, 43...output unit, 44...storage unit, 45...control unit, 451...communication control unit, 452...prescription information control unit, 453... Genetic related information control unit, 454... Feedback information control unit

Claims

1. a communication unit that communicates with other devices via a network; an output unit for outputting information to a user; a control unit that acquires information regarding drugs that require caution when used by the user among drugs prescribed for the user, and outputs the information regarding the drugs that require caution when used to the user via the output unit; Equipped with further comprising an input unit for receiving information input from a user; The control unit acquires feedback information indicating a state of the user after use of the drug prescribed for the user via the input unit, and provides the feedback information to another device via the communication unit; A user terminal, wherein the control unit provides the feedback information to a first information processing device when the feedback information does not include information regarding the user's genes, and provides the feedback information to a second information processing device different from the first information processing device when the feedback information includes information regarding the user's genes.

2. obtaining information on medicines prescribed to a user that require caution when taken by the user; outputting information about the medicines that require careful use to a user; an input step of receiving, from the user, feedback information indicating a state of the user after use of a drug prescribed for the user; providing the feedback information to another device via a communication unit that communicates with the other device via a network; A control method in which, in the providing step, if the feedback information does not include information regarding the user's genes, the feedback information is provided to a first information processing device, and if the feedback information includes information regarding the user's genes, the feedback information is provided to a second information processing device different from the first information processing device.

3. A communication unit that communicates with other devices via a network; an output unit for outputting information to a user; A control unit that acquires information about drugs that require caution when used by the user among drugs prescribed for the user, and outputs the information about the drugs that require caution when used to the user via the output unit, further comprising an input unit for receiving information input from a user; The control unit acquires feedback information indicating a state of the user after use of the drug prescribed for the user via the input unit, and provides the feedback information to another device via the communication unit; The control unit is a computer program for causing a computer to function as a user terminal that provides the feedback information to a first information processing device when the feedback information does not include information regarding the user's genes, and provides the feedback information to a second information processing device different from the first information processing device when the feedback information includes information regarding the user's genes.

Images