Controlled release and hierarchical cyclodextrin inclusion vehicles
JP7680756B2Active Publication Date: 2025-05-21CZAP RESEACH & DEV LLC
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Patent Information
- Application Number
- JP2022142626
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2017-01-09
- Filing Date
- 2022-09-08
- Publication Date
- 2025-05-21
- Estimated Expiration
- 2037-02-03
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Abstract
The present invention provides a biochemical construct for delivery of bioactive agents, comprising a delivery vehicle consisting of a molecule delivered together with a selected enzyme having cyclodextrin degrading activity and carried as an inclusion within a cyclodextrin. [Solution] The present invention provides a cyclodextrin inclusion delivery vehicle, in which the cyclodextrin inclusion is provided together with an enzyme having cyclodextrin-degrading activity that can digest the cyclodextrin, and upon delivery of the delivery vehicle to a target, the enzyme is activated to release the guest molecule from the cyclodextrin cavity.
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Citation Information
Patent Citations
Dissociation of hardly dissociable cyclodextrin clathrate substance
JP1984044318A
Sustained release drug preparation
US4869904A