Internal measurement system and program

Abstract

To provide a high accuracy in vivo measuring system suited to each person.SOLUTION: A simple BIA body composition meter 100 as an in vivo measuring system includes: a storage unit 110 for storing in vivo information acquired by the measurement of first accuracy as a reference value; a low accuracy measuring unit 104 for acquiring low accuracy in vivo information by inputting a measurement value acquired by the measurement of second accuracy lower than the first accuracy to a predetermined algorithm; a correction unit 112 for correcting the algorithm or the low accuracy in vivo information based on the reference value stored in the storage unit 110 and a degree of emphasis on the reference value; and an output unit 106 for outputting, as corrected in vivo information, the low accuracy in vivo information acquired by the low accuracy measuring unit 104 by using the algorithm corrected by the correction unit 112, or the low accuracy in vivo information acquired by the low accuracy measuring unit 104 and corrected by the correction unit 112.SELECTED DRAWING: Figure 2

Description

[Technical field]

[0001] The present invention relates to an internal body measurement system and a program. [Background technology]

[0002] Conventionally, there is known a BIA body composition analyzer that can measure internal body information such as body water content, body fat mass, and muscle mass based on bioelectrical impedance analysis (BIA). BIA body composition analyzers calculate internal body information that applies to many people using statistical formulas, and are therefore excellent at tracking relative changes in an individual's internal body information.

[0003] Patent documents 1 and 2 propose a method for measuring body fat mass by measuring the impedance between the body's extremities and calculating the body fat mass from the impedance value and physical values ​​such as the subject's height, weight, and sex. [Prior art documents] [Patent documents]

[0004] [Patent Document 1] U.S. Pat. No. 4,895,163 [Patent Document 2] Japanese Patent Application Publication No. 2-60626 Summary of the Invention [Problem to be solved by the invention]

[0005] When comparing the internal body information obtained by conventional BIA body composition analyzers with the internal body information obtained by high-precision measurement methods such as DXA (Dual Energy X-Ray Absorptiometry), MRI (Magnetic Resonance Imaging), CT (Computed Tomography), deuterium oxide dilution method, and 4C model (4 compartment model), there may be some differences in absolute values.

[0006] Furthermore, when comparing internal body information obtained from a simple BIA body composition monitor (e.g., a single-frequency four-electrode BIA body composition monitor, a whole-body BIA body composition monitor) with internal body information obtained from a high-precision BIA body composition monitor (e.g., a multi-frequency multi-electrode BIA body composition monitor, a body part-specific BIA body composition monitor) which has higher measurement accuracy of internal body information than a simple BIA body composition monitor, there may be a difference in absolute values.

[0007] An object of the present invention is to provide an in-vivo measuring system and a program for acquiring highly accurate in-vivo information. [Means for solving the problem]

[0008] In order to achieve the above-mentioned object, the present invention provides an in-vivo measurement system comprising a memory unit which stores in-vivo information obtained by a measurement with a first accuracy as a reference value, a low-accuracy measurement unit which acquires low-accuracy in-vivo information by inputting measurement values ​​obtained by a measurement with a second accuracy lower than the first accuracy into a predetermined algorithm, a correction unit which corrects the algorithm or the stored low-accuracy in-vivo information based on the reference value stored in the memory unit and the degree of importance given to the reference value, and an output unit which outputs the low-accuracy in-vivo information acquired by the low-accuracy measurement unit using the algorithm corrected by the correction unit, or the low-accuracy in-vivo information acquired by the low-accuracy measurement unit and corrected by the correction unit, as corrected in-vivo information.

[0009] With this configuration, corrected in-vivo information is obtained by inputting a measurement value obtained by a measurement with a second accuracy (hereinafter also referred to as "low accuracy") lower than the first accuracy to an algorithm corrected using a reference value (hereinafter also referred to as a "high accuracy reference value") obtained by a measurement with a first accuracy (hereinafter also referred to as "high accuracy"). Alternatively, the corrected in-vivo information is obtained by correcting the low accuracy in-vivo information of the user (hereinafter also referred to as "low accuracy in-vivo information") obtained by a low accuracy measurement unit using the high accuracy reference value. At this time, the high accuracy reference value for obtaining the corrected in-vivo information is not used as it is as the in-vivo information obtained by a high accuracy measurement, but is used after adjusting the high accuracy reference value using a degree of importance given to the high accuracy reference value (hereinafter also referred to as an "adjustment parameter"). Therefore, correction can be performed using a more appropriate high accuracy reference value, and high accuracy in-vivo information can be obtained as the corrected in-vivo information. In addition, the adjustment parameters may be determined to the extent necessary, for example, depending on the possibility or degree of difference in body composition between high-precision measurement and measurement of low-precision internal body information (hereinafter also referred to as the "low-precision reference value") for adjusting the high-precision reference value to determine the correction method (hereinafter also referred to as the "time when the correction method is determined").It is also possible that the high-precision reference value need not be adjusted.

[0010] The degree may be determined according to the contribution of the reference value stored in the storage unit to the low-accuracy intra-vivo information acquired by the low-accuracy measurement unit.

[0011] With this configuration, the degree can be determined taking into consideration the contribution of the low-accuracy in-vivo information to the reference value.

[0012] The degree may be determined based on the difference between the weight when the first accuracy measurement is taken and the weight when corrected for the algorithm or low accuracy internal body information.

[0013] With this configuration, the possibility or degree of difference in body composition between the time of high-precision measurement and the time of determining the correction method can be determined based on the difference in body weight.

[0014] The degree may be determined based on the time between making the first accuracy measurement and correcting the algorithm or the low accuracy in-vivo information.

[0015] With this configuration, the possibility or degree of difference in body composition between the time of high-precision measurement and the time of determining the correction method can be determined based on the period from the time of high-precision measurement to the time of determining the correction method.

[0016] The degree may also be determined based on the difference between the reference value and the low-accuracy in-vivo information acquired by the algorithm or the low-accuracy measuring unit when correcting the low-accuracy in-vivo information.

[0017] With this configuration, the possibility or degree of difference in body composition between the time of high-precision measurement and the time of determining the correction method can be determined based on the difference between the reference value and the low-precision internal information as the low-precision reference value.

[0018] The degree may be determined based on a user's preference.

[0019] This configuration allows the degree to be determined based on the user's selection.

[0020] The storage unit may store the corrected algorithm or a correction function for correcting the low-precision in-vivo information and the corrected in-vivo information.

[0021] This configuration stores the corrected algorithm or correction function and the corrected in-body information so that they can be referenced later.

[0022] The apparatus may further include an input unit that receives the in vivo information obtained by the measurement of the first accuracy and inputs it as a reference value.

[0023] This configuration allows the reference value to be input easily.

[0024] The output unit may display the corrected in-vivo information in a different appearance so as to distinguish it from the low-accuracy in-vivo information acquired by inputting the measurement value in the low-accuracy measurement unit into a predetermined algorithm.

[0025] This configuration allows the user to know whether or not the accuracy of the in-vivo information has been improved.

[0026] The output unit may display information relating to the accuracy of the corrected in-vivo information based on the degree.

[0027] This configuration allows the user to know how accurate the measurement results are.

[0028] The output unit may display an alert based on the period from when the high-accuracy measurement is performed to when the low-accuracy in-vivo information is acquired.

[0029] This configuration can encourage users to perform new high-precision measurements, and motivate them to improve the accuracy of their in-body measurement systems.

[0030] In order to achieve the above object, the present invention provides an in-vivo measurement program that causes a computer to function as a memory unit, a low-accuracy measurement unit, a correction unit, an output unit, and an input unit that constitute the above-mentioned in-vivo measurement system. [Brief description of the drawings]

[0031] [Figure 1] FIG. 1 is a perspective view of a simplified BIA body composition meter according to one embodiment of the present invention. [Diagram 2] FIG. 2 is a block diagram showing the functional configuration of a simplified BIA body composition meter according to one embodiment of the present invention. [Diagram 3] 4 is a first flowchart showing the operation of the simplified BIA body composition monitor for determining a correction function according to the first embodiment of the present invention. [Figure 4] 5 is a second flowchart showing the operation of the simplified BIA body composition monitor for determining a correction function according to the first embodiment of the present invention. [Diagram 5] FIG. 2(a) is a diagram showing a first result display screen of the simplified BIA body composition monitor according to the first embodiment of the present invention, and FIG. 2(b) is a diagram showing a second result display screen of the simplified BIA body composition monitor according to the first embodiment of the present invention. [Figure 6] 11 is a first flowchart showing the operation of the simplified BIA body composition monitor for determining a correction function according to the second embodiment of the present invention. [Figure 7] 13 is a second flowchart showing the operation of the simplified BIA body composition monitor for determining a correction function according to the third embodiment of the present invention. [Figure 8] FIG. 1 is a front view of a card-type simplified BIA body composition meter according to one embodiment of the present invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS

[0032] Hereinafter, an embodiment of the present invention will be described with reference to the drawings. Note that the embodiment described below shows an example of a case where the present invention is implemented, and the present invention is not limited to the specific configuration described below. In implementing the present invention, a specific configuration according to the embodiment may be appropriately adopted.

[0033] [Body composition scale configuration] 1 is a perspective view of a simplified BIA body composition analyzer 100 according to one embodiment of the present invention. The simplified BIA body composition analyzer 100 has an input unit 102, a low-accuracy measurement unit 104, and an output unit 106.

[0034] The input unit 102 is a means for inputting information to the simplified BIA body composition analyzer 100. The method for inputting information to the input unit 102 may be a manual method, a method via a recording medium, a method via wired communication, a method via wireless communication, or other method.

[0035] The manual input method may be, for example, a button type, a dial type, or a touch sensor type. The method via a recording medium may be, for example, a flash memory type, a CD-ROM type, or a DVD-ROM type. The wireless communication method may be, for example, an Internet type, a wireless LAN type such as Wi-Fi (registered trademark), or a short-range wireless communication type such as Bluetooth (registered trademark) or NFC (Near Field Communication). In this embodiment, the input unit 102 is a manual input method and is a button type.

[0036] Information related to body composition is input to the input unit 102. Specifically, information that cannot be measured by the simplified BIA body composition meter 100, such as age, height, and sex, is input to the input unit 102.

[0037] In addition, the input unit 102 further inputs high-precision internal body information (high-precision reference values) measured by a body composition measurement (estimation) method (e.g., DXA, MRI, CT, heavy water dilution method, 4C model) that has higher measurement accuracy of internal body information than a simple BIA body composition analyzer and a high-precision BIA body composition analyzer (multi-frequency multi-electrode BIA body composition analyzer, body part-specific BIA body composition analyzer), among internal body information such as body fat percentage, body fat mass, muscle mass, abdominal muscle / back muscle ratio, body water content, bone mass, visceral fat area, basal metabolism, etc.

[0038] Furthermore, the input unit 102 also receives input of the weight and the measurement date and time when the high-precision internal body information is measured.

[0039] The input information is stored in storage unit 110, which will be described later.

[0040] The low-accuracy measurement unit 104 is a measurement means for measuring low-accuracy internal body information (low-accuracy internal body information) of a user by inputting a measurement value into a predetermined algorithm. The measurement value is, for example, weight, impedance, etc. The predetermined algorithm may be, for example, a regression equation for calculating low-accuracy internal body information from a measurement value, or may be a machine learning model for inputting a measurement value and outputting low-accuracy internal body information. In this embodiment, the low-accuracy measurement unit 104 has a weight measurement means for measuring the weight of the user, a bioimpedance measurement means for measuring the bioimpedance of the user by BIA, a date and time specification means for specifying the date and time of measurement, and a calculation means for calculating low-accuracy internal body information by inputting at least the bioimpedance into an algorithm as a measurement value.

[0041] Whether the measurement method is low-precision or high-precision is determined relatively. In general, the measurement unit of a BIA body composition meter can measure internal body information with higher precision when it has more types of frequencies of applied current, has more electrodes, and can measure each part of the body rather than the whole body. For example, the measurement unit of a multi-frequency multi-electrode BIA body composition meter has higher internal body information measurement precision than the measurement unit of a single-frequency four-electrode BIA body composition meter, and the measurement unit of a part-specific BIA body composition meter has higher internal body information measurement precision than the measurement unit of a whole-body type BIA body composition meter. In this embodiment, the low-precision measurement unit 104 is a measurement unit that measures low-precision internal body information of a single-frequency four-electrode type.

[0042] The output unit 106 is an output means for outputting the measurement results of the user. The output unit 106 is, for example, an LCD (Liquid Crystal Display) or an OLED (Organic Light Emitting Diode). The output unit 106 may be integrated with the simplified BIA body composition meter 100, or may not be integrated with the simplified BIA body composition meter 100, such as a smartphone or tablet. In this embodiment, the output unit 106 is an LCD integrated with the simplified BIA body composition meter 100.

[0043] The output unit 106 outputs the measurement results of the user. The output may be, for example, a display of numerical values, characters, a diagram of a body shape, or the like that reflects the measurement results of the user, or may be an output in the form of voice or other formats. In this embodiment, the output unit 106 displays the weight measured by the low-accuracy measurement unit 104, low-accuracy internal body information, corrected internal body information to be described later, information related to the measurement accuracy, and an alert that prompts the measurement of a high-accuracy reference value.

[0044] 2 is a block diagram showing the functional configuration of a simplified BIA body composition analyzer 100 according to an embodiment of the present invention. The simplified BIA body composition analyzer 100 has a control unit 108, a storage unit 110, and a correction unit 112 in addition to the input unit 102, low-accuracy measurement unit 104, and output unit 106 as shown in FIG.

[0045] The control unit 108 is a control device that controls the input unit 102, the low-accuracy measurement unit 104, the output unit 106, the storage unit 110, and the correction unit 112. The control unit 108 has a CPU (Central Processing Unit). The control unit 108 is electrically connected to each unit. The control unit 108 executes a program stored in the storage unit 110 to realize the function of each unit.

[0046] The storage unit 110 is a memory capable of storing data. The memory may be, for example, a volatile memory (for example, a RAM) or a non-volatile memory (for example, a ROM). The storage unit 110 may be built into the simplified BIA body composition analyzer 100 as shown in FIG. 2, or may be provided outside the simplified BIA body composition analyzer 100, such as an external hard disk drive or an external server. In this embodiment, the storage unit 110 is built into the simplified BIA body composition analyzer 100.

[0047] The storage unit 110 stores the program executed by the control unit 108, the correction function described below, the corrected internal body information, and the like.

[0048] Furthermore, the storage unit 110 stores information input to the input unit 102. Specifically, the storage unit 110 stores information such as age, height, sex, high-precision reference value, weight when the high-precision internal information was measured, and measurement date and time input to the input unit 102.

[0049] Furthermore, the storage unit 110 stores information used by the low-accuracy measurement unit 104. Specifically, the storage unit 110 stores, as information used by the low-accuracy measurement unit 104, information such as, for example, the weight, age, height, sex, statistical information related to internal body information of the user in general, and a predetermined algorithm (for example, a regression equation) for acquiring low-accuracy internal body information from measurement values ​​obtained by low-accuracy measurement.

[0050] Furthermore, the storage unit 110 stores information acquired by the low-accuracy measurement unit 104. Specifically, the storage unit 110 stores information acquired by the low-accuracy measurement unit 104, such as weight, impedance, low-accuracy internal body information, measurement date and time, and corrected internal body information to be described later.

[0051] The correction unit 112 is a correction means for correcting the algorithm or the low-precision internal information based on the high-precision reference value stored in the storage unit 110 and the degree of importance given to the reference value (adjustment parameter). The adjustment parameter is a parameter for adjusting the high-precision reference value by, for example, multiplying or adding to the high-precision reference value. The correction unit 112 may be built into the simplified BIA body composition analyzer 100 as shown in FIG. 2, or may be provided outside the simplified BIA body composition analyzer 100, such as an external server. In this embodiment, the correction unit 112 is built into the simplified BIA body composition analyzer 100.

[0052] As described above, since the measurement by the low-accuracy measuring unit 104 is relatively low-accuracy, even if a body composition equal to the body composition at the time when a high-accuracy reference value is obtained by performing a high-accuracy measurement, a difference may occur between the low-accuracy internal body information measured by the low-accuracy measuring unit 104 and the high-accuracy reference value. Therefore, the correction unit 112 of this embodiment determines a correction function for correcting the low-accuracy internal body information so as to reduce this difference.

[0053] However, in order to consider that the difference between the high-precision reference value and the low-precision internal body information (low-precision reference value) at the time of measuring the low-precision internal body information for determining the correction function, i.e., at the time of determining the correction method, is due to the measurement accuracy of the low-precision measurement unit 104, it is prerequisite that the body composition at the time of measuring the high-precision reference value and the body composition at the time of determining the correction method are the same or very close to each other. If the body compositions (i.e., true values) at both points in time are different, the ratio of the elements attributable to changes in body composition and the elements attributable to the measurement accuracy of the low-precision measurement unit 104 in the difference between the high-precision reference value and the low-precision reference value becomes unclear.

[0054] Therefore, the correction unit 112 determines the contribution degree of the high-precision reference value to the low-precision reference value used in determining the adjustment parameter (hereinafter referred to as the "contribution degree of the high-precision reference value") according to the possibility or degree of difference between the body composition when the high-precision reference value is obtained and the body composition when the correction method is determined, and determines the adjustment parameter according to this contribution degree. In consideration of the above circumstances, the contribution degree of the high-precision reference value is determined based on the following predetermined conditions.

[0055] The predetermined condition may be, for example, an index of the absolute value of the difference between the weight when the high-precision reference value was obtained and the weight when the correction method was determined (hereinafter, referred to as "weight difference").

[0056] Specifically, when the weight difference is smaller than α (weight difference<α), the weight deviation is small, so the change in body composition between the time the high-precision reference value is obtained and the time the correction method is determined is small, and the contribution of the high-precision reference value is determined to be large. At this time, the correction unit 112 determines an adjustment parameter Y0 according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by a primary adjustment "Y0 x high-precision reference value" in which Y0 is multiplied by the high-precision reference value. As a specific value of Y0, a different value is adopted depending on whether the weight has increased or decreased, and a different value is adopted depending on the type of body information (e.g., body fat mass, muscle mass, body water mass, etc.) that is regarded as the high-precision reference value.

[0057] When the weight at the time of determining the correction method has increased compared to the weight at the time the high-precision reference value was obtained, Y0 used to adjust the body fat (amount / percentage), which is the high-precision reference value, is set to 1 or a value slightly smaller than 1, Y0 used to adjust the muscle mass is set to 1 or a value slightly larger than 1, and Y0 used to adjust the body water content is set to 1 or a value slightly larger than 1. Note that setting Y0 to 1 is synonymous with not performing the primary adjustment.

[0058] On the other hand, when the body weight at the time of determining the correction method has decreased compared to the body weight at the time the high-precision reference value was obtained, Y0 used to adjust the body fat (amount / percentage), which is the high-precision reference value, shall be 1 or a value slightly larger than 1, Y0 used to adjust the muscle mass shall be 1 or a value slightly smaller than 1, and Y0 used to adjust the body water content shall be 1 or a value slightly smaller than 1.

[0059] When the weight difference is equal to or greater than α but smaller than β (weight difference < β), the weight difference is considered to be "weight difference < α". Since a certain degree of weight deviation is observed from time to time, it is considered that there is a change in body composition between the time when the high-precision reference value is obtained and the time when the correction method is determined, and it is determined that the contribution of the high-precision reference value to the low-precision reference value decreases as the weight difference increases. At this time, the correction unit 112 determines adjustment parameters Y1 to Y5 (hereinafter referred to as "Y1 to 5") according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by a primary adjustment "Y1 to 5 x high-precision reference value" in which Y1 to 5 are multiplied by the high-precision reference value. As for the specific values ​​of Y1 to 5, similar to Y0, different values ​​are adopted depending on whether the weight has increased or decreased, and different values ​​are adopted depending on the type of body information (e.g., body fat mass, muscle mass, body water mass, etc.) that is regarded as the high-precision reference value.

[0060] When the body weight at the time of determining the correction method has increased compared to the body weight at the time the high-precision reference value was obtained, Y1 to 5 used to adjust the body fat (amount / percentage), which is the high-precision reference value, are set to values ​​smaller than 1, Y1 to 5 used to adjust the muscle mass are set to values ​​greater than 1, and Y1 to 5 used to adjust the body water content are set to values ​​greater than 1.

[0061] On the other hand, when the body weight at the time of determining the correction method has decreased compared to the body weight at the time the high-precision reference value was obtained, Y1 to 5 used to adjust the body fat (amount / percentage), which is the high-precision reference value, are set to values ​​greater than 1, Y1 to 5 used to adjust the muscle mass are set to values ​​less than 1, and Y1 to 5 used to adjust the body water content are set to values ​​less than 1.

[0062] When the weight difference is β or more (weight difference ≧ β), the high-precision reference value and the simple BIA body composition meter 1 When the absolute value of the difference with the low-precision internal information by 00 (hereinafter referred to as "internal difference") is γ or more (internal difference ≧ γ), a deviation in body weight is observed, and although there is a change in body composition between when the high-precision reference value is obtained and when the correction method is determined, the contribution of the high-precision reference value is determined to be somewhat low in order to reflect the user's body composition, which deviates significantly from the average body composition estimated from the statistical values. In this case, the high-precision reference value is adjusted by the primary adjustment "Y1~5 × high-precision reference value" similar to "weight difference < β".

[0063] When the above-mentioned conditions related to the weight difference and internal difference are not satisfied, it is considered that the change in body composition is large between the time when the high-precision reference value was obtained and the time when the correction method was decided, and it is determined that the contribution of the high-precision reference value is small. At this time, the correction unit 112 does not perform correction based on the high-precision reference value adjusted by the adjustment parameter.

[0064] Furthermore, the predetermined condition may be, for example, an index of the period from when the high-precision reference value is acquired to when the correction method is determined (hereinafter, referred to as "the number of elapsed days").

[0065] Specifically, when the number of days elapsed is "z1 days or less", since the number of days elapsed is relatively short, it is considered that the change in body composition between the time the high-precision reference value was obtained and the time the correction method was decided is small, and it is determined that the contribution of the high-precision reference value is large. At this time, the correction unit 112 performs only the primary adjustment, and does not perform the adjustment of the high-precision reference value based on the number of days elapsed (secondary adjustment).

[0066] When the number of elapsed days is z1 days but within "z2 days", since the number of elapsed days can be seen to some extent, it is considered that there is a change in body composition between the acquisition of the high-precision reference value and the determination of the correction method, and it is determined that the contribution degree of the high-precision reference value is slightly low. At this time, the correction unit 112 adjusts the high-precision reference value after the first adjustment using the low-precision reference value according to the contribution degree of the high-precision reference value. Specifically, the correction unit 112 adjusts the high-precision reference value by the second adjustment "(a × Y0~5 × high-precision reference value + b × low-precision reference value) / 2". Note that the second adjustment parameters a and b may satisfy, for example, 0 < a < 1 and b = 1 - a. The correction unit 112 makes the value of a smaller and the value of b larger as the number of elapsed days is longer. The high-precision reference value is adjusted by the second adjustment "(a × Y0~5 × high-precision reference value + b × low-precision reference value) / 2".

[0067] Also, as the first adjustment parameters Y0~5 in the case of performing the second adjustment (that is, when the number of elapsed days is greater than z1 and within z2), values different from the values of Y0~5 in the case of performing only the first adjustment (that is, when the number of elapsed days is within z1) may be adopted. This is because when the number of elapsed days is "within z1 days", that is, when the number of elapsed days is relatively short, it is considered that the reason for the weight difference is the change in body water content, while when the number of elapsed days exceeds z1 days, that is, when the number of elapsed days is relatively long, it is difficult to identify the reason for the weight difference. Thus, the reason for the weight difference is different between the case of a short number of elapsed days and the case of a long number of elapsed days.

[0068] When the weight at the time of determining the correction method has increased compared to the weight at the time of acquiring the high-precision reference value, all of Y0~5 used for adjusting the body fat (quantity / rate), muscle mass, and body water content, which are the high-precision reference values, are set to values of 1 or more.

[0069] On the other hand, when the weight at the time of determining the correction method has decreased compared to the weight at the time of acquiring the high-precision reference value, all of Y0~5 used for adjusting the body fat (quantity / rate), muscle mass, and body water content, which are the high-precision reference values, are values of 1 or less.

[0070] If the above-mentioned condition related to the number of days elapsed is not satisfied, that is, if the number of days elapsed is z2 or more, it is considered that the change in body composition between the time when the high-precision reference value was obtained and the time when the correction method was decided is large, and it is determined that the contribution of the high-precision reference value is low. In this case, the correction unit 112 does not decide the adjustment parameter and does not adjust the high-precision reference value.

[0071] However, if the first adjustment "Y0~5 × high-precision reference value" has been performed and z2 days have passed, but the user selects the second adjustment (hereinafter referred to as "adjustment selection"). The adjustment parameters for the second adjustment are determined, and the second adjustment "(a × Y0~5 × high-precision reference value + b × low The high accuracy standard value may be adjusted by "accuracy standard value) / 2".

[0072] In addition, the weight difference has a larger effect on changes in body composition than the number of days elapsed. Therefore, the adjustment parameters Y0 to 5 of the primary adjustment, which reflect the contribution of the high-precision reference value, are parameters that are greatly influenced by the weight difference. On the other hand, the adjustment parameters a and b of the secondary adjustment, which also reflect the contribution of the high-precision reference value, are parameters that are not so greatly influenced by the number of days elapsed. In other words, there is a qualitative difference between the adjustment parameters Y0 to 5 of the primary adjustment and the adjustment parameters a and b of the secondary adjustment in the degree of influence of the weight difference and the number of days elapsed on the parameters.

[0073] Furthermore, since the predetermined condition is a condition for determining the contribution of the high-precision reference value, for example, the ratio of the body weight when the high-precision reference value is obtained to the body weight when the correction method is determined may be used as the index.

[0074] Furthermore, even if the predetermined condition uses weight difference as an index, it may be divided into fewer or more stages rather than into three stages, "weight difference<α", "weight difference<β", and "weight difference≧β". Similarly, even if the predetermined condition uses the number of days elapsed as an index, it may be divided into fewer or more stages rather than into two stages, "within z 1 day" and "within z 2 days".

[0075] Furthermore, the adjustment of the high-precision reference value may not only be performed by performing a primary adjustment followed by a secondary adjustment, but may also be performed by performing a tertiary or higher adjustment, such as further weighting after the secondary adjustment. That is, the formula for calculating the adjusted high-precision reference value may be obtained using several adjustment formulas.

[0076] As described above, when the adjustment parameter is determined and the high-precision reference value is adjusted, the correction unit 112 determines a correction function that relates the corrected in-vivo information to the low-precision in-vivo information based on the high-precision reference value and the low-precision reference value adjusted using the adjustment parameter. Then, the low-precision in-vivo information is corrected by this correction function to obtain the corrected in-vivo information. In the measurement after the correction function is determined, the correction unit 112 corrects the low-precision in-vivo information calculated by the low-precision measurement unit 104 using a predetermined algorithm by this correction function to obtain the corrected in-vivo information. When a new high-precision reference value is obtained, the correction function can be updated.

[0077] The correction function is, for example, (Corrected internal information) = c × (low-accuracy internal information) + d (1) (Corrected internal information) = c × (low-accuracy internal information) ···(2) (Corrected internal information) = (low-accuracy internal information) + d (3) The parameters c and d of the correction function may be expressed as follows for the formulas (1) to (3): (Adjusted high-precision reference value) = c × (low-precision reference value) + d (1´) (Adjusted high-precision reference value) = c × (low-precision reference value) (2´) (Adjusted high-precision reference value) = (low-precision reference value) + d (3´) is determined so as to satisfy

[0078] [Operation of the body composition monitor according to the first embodiment] The following describes a flow for implementing the operation of the body composition meter according to the first embodiment using the above-mentioned configuration of the body composition meter. This flow can be performed every time a high-precision reference value is input to the simplified BIA body composition meter 100. In this flow, a correction function is determined using a high-precision reference value and a low-precision reference value. In measurements after the correction function is determined, the low-precision internal information can be corrected using this correction function.

[0079] 3 is a first flow chart showing the operation of the simplified BIA body composition analyzer 100 for determining a correction function according to the first embodiment of the present invention. The first flow according to the first embodiment is a flow for performing a primary adjustment of high-precision internal information using a weight difference as an index. When a user operates the simplified BIA body composition analyzer 100 to start the process of determining a correction function, the first flow starts.

[0080] First, the low-accuracy measurement unit 104 measures the internal body information of the user (step S102).

[0081] When the low-accuracy measurement unit 104 measures the internal body information of the user, the storage unit 110 stores a low-accuracy reference value (step S104).

[0082] When the memory unit 110 stores the low-accuracy reference value, the correction unit 112 determines whether or not there is a high-accuracy reference value stored in the memory unit 110 (step S106) and the weight difference (step S108).

[0083] If it is determined that "weight difference < α" with "high-precision reference value available" stored in memory unit 110 (step S106: Yes, step S108: Yes), correction unit 112 determines adjustment parameter Y0 according to the contribution of the high-precision reference value, adjusts the high-precision reference value by the primary adjustment "Y0 × high-precision reference value" (step S110), and the flow ends.

[0084] That is, when it is determined that "body weight difference<α", the body weight deviation is small, so it is considered that the change in body composition between the time the high-precision reference value was obtained and the time the correction method was decided is small, and it is determined that the contribution of the high-precision reference value is large. At this time, the correction unit 112 determines an adjustment parameter Y0 according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by the primary adjustment "Y0 × high-precision reference value".

[0085] On the other hand, if it is determined that "weight difference<α" is not true with "high-precision reference value available" stored in memory unit 110 (step S106: Yes, step S108: No), correction unit 112 again determines the weight difference (step S112). Then, if it is determined that "weight difference<β" is true (step S112: Yes), correction unit 112 determines adjustment parameters Y1-5 according to the contribution of the high-precision reference value, adjusts the high-precision reference value by the primary adjustment "Y1-5×high-precision reference value" (step S114), and the flow ends.

[0086] That is, when it is determined that "weight difference<β", there is a certain degree of weight deviation compared to when it is determined that "weight difference<α", so it is assumed that there has been a change in body composition between the time the high-precision reference value was obtained and the time the correction method was decided, and it is determined that the contribution of the high-precision reference value is somewhat low. At this time, the correction unit 112 determines adjustment parameters Y1-5 according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by the primary adjustment "Y1-5 × high-precision reference value".

[0087] On the other hand, if it is determined that there is not a "high-precision reference value" stored in memory unit 110 (step S106: No), or if it is determined that there is a "high-precision reference value" but the weight difference is not "weight difference < α" or not "weight difference < β" (step S106: Yes, step S108: No, step S112: No), correction unit 112 does not correct the low-precision reference value using a correction function based on the primarily adjusted high-precision reference value (step S116), and memory unit 110 simply stores the high-precision reference value as a reference value, and the flow ends.

[0088] That is, when it is determined that there is a "high-precision reference value" but the weight difference is not "<α" or "<β", it is assumed that there was a large change in body composition between the time the high-precision reference value was obtained and the time the correction method was determined, and it is determined that the contribution of the high-precision reference value is small. In this case, the correction unit 112 does not perform correction.

[0089] As described above, in the first flow according to the first embodiment, the contribution of the high-precision reference value is evaluated using the weight difference as an index. When the weight difference is small (weight difference<α), the high-precision reference value is adjusted by the primary adjustment "Y0 × high-precision reference value", when there is a certain degree of weight difference (weight difference<β), the high-precision reference value is adjusted by the primary adjustment "Y1-5 × high-precision reference value", and when the weight difference is large (weight difference≧β), no correction is performed.

[0090] In this way, in the first flow according to the first embodiment, even if there is a change in body composition to some extent between the time when the high-precision reference value is obtained and the time when the correction method is determined, the adjustment parameter reflecting the contribution of the high-precision reference value is determined, and the high-precision reference value is adjusted by this adjustment parameter. In particular, in this embodiment, the contribution is evaluated based on the weight difference that is not due to the difference in the measurement method, and the adjustment parameter reflecting the contribution in detail can be determined.

[0091] In other words, when a difference occurs between the high-precision reference value and the low-precision reference value, even if the low-precision internal information is corrected, it is necessary to determine whether such a difference is due to the measurement accuracy of the simple BIA body composition meter 100 or due to a change in the user's body composition.

[0092] Therefore, using the difference in body weight as an indicator, when the difference in body weight is small and the identity of the user's body composition can be guaranteed, it is determined that the difference between the high-precision reference value and the low-precision reference value is due to the measurement accuracy of the simple BIA body composition meter 100, and adjustment parameters are determined so that the contribution of the high-precision reference value is greater.

[0093] On the other hand, when the weight difference is large and the identity of the user's body composition cannot be guaranteed, it is determined that the difference between the high-precision reference value and the low-precision reference value is due to a change in the user's body composition, and adjustment parameters are determined so that the contribution of the high-precision reference value is reduced. Therefore, a highly accurate internal measurement system and program tailored to the individual can be provided.

[0094] 4 is a second flow chart showing the operation of the simplified BIA body composition meter 100 for determining a correction function according to the first embodiment of the present invention. The second flow is a flow for further secondarily adjusting the high-precision reference value that has been primarily adjusted, using the number of days that have passed as an index. When the first flow ends, the second flow starts.

[0095] When the second flow starts, the correction unit 112 determines whether or not a first adjustment has been performed (step S202) and the number of days that have passed (step S204).

[0096] If it is determined that "primary adjustment is performed" and the number of days that have passed is "z 1 days or less" (step S202: Yes, step S204: Yes), the correction unit 112 does not perform the secondary adjustment (step S206), but determines a correction function based on the primarily adjusted high-precision reference value, corrects the low-precision reference value using this correction function, and the output unit 106 displays the low-precision in-vivo information as the corrected low-precision reference value as the corrected in-vivo information (step S208). Then, the storage unit 110 stores the correction function and the corrected in-vivo information (step S210), and the flow ends.

[0097] That is, when the first adjustment is performed and the number of days that have passed is "within z days", it is considered that the change in body composition between the time when the high-precision reference value was obtained and the time when the correction method was decided is small, and it is determined that the contribution of the high-precision reference value is high. In this case, the correction unit 112 does not perform the second adjustment.

[0098] On the other hand, if it is determined that the number of days elapsed with "primary adjustment" is not "within z days" (step S202: Yes, step S204: No), the correction unit 112 again determines the number of days elapsed (step S212).

[0099] If it is determined that the number of days that have passed is "within z2 days" (step S212: Yes), the correction unit 112 determines the adjustment parameters Y0 to 5, a, and b according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by the secondary adjustment "(a x Y0 to 5 x high-precision reference value + b x low-precision reference value) / 2". Then, the correction unit 112 determines a correction function based on the second-adjusted high-precision reference value and corrects the low-precision reference value by this correction function, the output unit 106 displays the low-precision in-vivo information as the corrected low-precision reference value as corrected in-vivo information (step S216), the storage unit 110 stores the correction function and the corrected in-vivo information (step S210), and the flow ends.

[0100] That is, when the number of days elapsed is determined to be "within z2 days" with "primary adjustment", it is assumed that there has been a change in body composition between the time the high-precision reference value was obtained and the time the correction method was determined, and it is determined that the contribution of the high-precision reference value is somewhat low. At this time, the correction unit 112 determines adjustment parameters Y0-5, a, and b according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by the secondary adjustment "(a×Y0-5×high-precision reference value+b×low-precision reference value) / 2".

[0101] On the other hand, if it is determined that "primary adjustment has been performed" (step S202: No) or if it is determined that "primary adjustment has been performed" and the number of days that have passed is not "within z2 days" (step S202: Yes, step S204: No, step S212: No), the correction unit 112 does not correct the low-accuracy reference value using a correction function, the output unit 106 displays the low-accuracy in-vivo information as the low-accuracy reference value (step S218), the memory unit 110 stores the low-accuracy in-vivo information as the low-accuracy reference value (step S220), and the flow ends.

[0102] That is, when it is not determined that "primary adjustment is performed", or when it is determined that the number of days elapsed is not "z2 days or less" even if "primary adjustment is performed", it is considered that the change in body composition is large between the time when the high-precision reference value was obtained and the time when the correction method was decided, and it is determined that the contribution of the high-precision reference value is small. In this case, the correction unit 112 does not perform correction.

[0103] As described above, in the second flow according to the first embodiment, the contribution of the high-precision reference value is evaluated using the number of days that have passed as an index. When the primary adjustment is performed and very few days have passed (within z1 days), the low-precision in-vivo information is corrected as the low-precision reference value by a correction function based on the primarily adjusted high-precision reference value, the low-precision in-vivo information is displayed as the corrected low-precision reference value as the corrected in-vivo information, and the correction function and the corrected in-vivo information are stored.

[0104] In addition, when a certain amount of time has passed (within z2 days), the low-precision in-vivo information as a low-precision reference value is corrected using a correction function based on the second-adjusted high-precision reference value, the low-precision in-vivo information as the corrected low-precision reference value is displayed as corrected in-vivo information, and the correction function and the corrected in-vivo information are stored.

[0105] In addition, when the primary adjustment is not performed, or when the primary adjustment is performed but z2 days have passed, the low-precision in-vivo information is displayed as a low-precision reference value without correction using a correction function, and the low-precision in-vivo information is stored as a low-precision reference value.

[0106] In this way, in the second flow, even if there is a change in body composition to some extent between the time when the high-precision reference value is obtained and the time when the correction method is determined, the adjustment parameter reflecting the contribution of the high-precision reference value is determined, and the high-precision reference value is adjusted using this adjustment parameter, so that the correction function can be determined using the high-precision reference value and the low-precision reference value. In particular, in this embodiment, the contribution of the high-precision reference value is evaluated based on the passage of time, and the adjustment parameter reflecting the contribution of the high-precision reference value in detail can be determined.

[0107] In other words, if a difference occurs between the high-precision reference value and the low-precision internal body information as the low-precision reference value when the correction method is determined, even if the low-precision internal body information as the low-precision reference value is corrected, it is necessary to determine whether such a difference is due to the measurement accuracy of the simple BIA body composition meter 100 or due to a change in the user's body composition.

[0108] Therefore, using the passage of time as an indicator, when no time has passed and the identity of the user's body composition can be guaranteed, it is determined that the difference between the high-precision reference value and the low-precision internal information as the low-precision reference value when the correction method is determined is due to the measurement accuracy of the simple BIA body composition meter 100, and adjustment parameters are determined so that the contribution of the high-precision reference value is greater.

[0109] On the other hand, when time has passed and the identity of the user's body composition cannot be guaranteed, it is determined that the difference between the high-precision reference value and the low-precision internal information as the low-precision reference value at the time of determining the correction method is due to a change in the user's body composition, and the adjustment parameters are determined so that the contribution of the high-precision reference value is reduced. Therefore, a highly accurate internal measurement system and program tailored to the individual can be provided.

[0110] In addition, in the second flow, the correction function and corrected internal body information can be stored, and by reflecting the correction function and corrected internal body information in future internal measurements, the more the simplified BIA body composition meter 100 is used, the more accurately it can reflect individual differences, making it possible to provide a highly accurate internal body measurement system and program tailored to the individual.

[0111] In addition, since the evaluation is not based on a predetermined algorithm (for example, a regression equation) but on an individual-specific correction function that is tailored to the individual's highly accurate standard value, it is possible to obtain highly accurate body composition measurement results that are tailored to individual differences while still being a simple measurement. Furthermore, since the relative changes from that value can be tracked using the simplified BIA body composition meter 100, unlike the body composition measurement (estimation) method that is usually difficult to measure and the measurement using a highly accurate BIA body composition meter, it is possible to capture detailed daily changes at the right time when you want to know them without missing them, and since it is possible to combine the advantages of both, it is possible to provide a highly accurate internal measurement system and program that are tailored to the individual.

[0112] In addition, by making the second flow, which reflects low-precision internal body information as low-precision reference values ​​via adjustment parameters a and b, subordinate to the first flow, which reflects only high-precision reference values ​​via adjustment parameters Y0 to 5, excessive correction by the first flow can be prevented, thereby providing a highly accurate internal body measurement system and program tailored to each individual.

[0113] FIG. 5(a) is a diagram showing a first result display screen of the simplified BIA body composition analyzer 100 according to the first embodiment of the present invention, and FIG. 5(b) is a diagram showing a second result display screen of the simplified BIA body composition analyzer 100 according to the first embodiment of the present invention.

[0114] 5(a), the output unit 106 displays the corrected internal body information 200A. For example, the output unit 106 displays the following as the corrected internal body information 200A: body fat percentage: 17%, body fat mass: 10 kg, muscle mass: 55 kg, abdominal / back muscle ratio: 1:2, total body water: 48 kg, bone mass: 3.4 kg, visceral fat area: 77 cm2, basal metabolism: 1200 kcal. This allows the user to know the corrected internal body information.

[0115] 5(b), the output unit 106 changes the appearance of the corrected internal body information 200B so that the corrected internal body information 200B and the low-accuracy internal body information can be distinguished from each other. Changing the appearance of the corrected internal body information 200B means adding a mark such as a star, changing the font, size, or color of the characters, or displaying a body composition measurement (estimation) method and a message indicating that a high-accuracy BIA body composition meter has been referenced.

[0116] In this embodiment, the output unit 106 displays: ☆Body fat percentage: 17% (DXA referenced!), ☆Body fat mass: 10 kg (DXA referenced!), ☆Muscle mass: 55 kg (DXA referenced!), ☆Abdominal / back muscle ratio: 1:2 (MRI referenced!), ☆Total body water: 48 kg (deuterium oxide dilution method referenced!), ☆Bone mass: 3.4 kg (DXA referenced!), ☆Visceral fat area: 77 cm2 (CT referenced!), Basal metabolic rate: 1200 kcal (BIA regression equation).

[0117] In other words, the corrected internal body information 200B excluding "Basal metabolism: 1200 kcal (BIA regression formula)" is marked with a star and displayed in association with the body composition measurement (estimation) method and the measurement method of the high-precision BIA body composition meter, while "Basal metabolism: 1200 kcal (BIA regression formula)" is not displayed, and the appearance of the corrected internal body information 200B is changed to make it possible to distinguish between the corrected internal body information 200B and the low-precision internal body information.

[0118] 5(b), the output unit 106 displays information 202B relating to the accuracy of the corrected in-vivo information based on the degree. The output unit 106 displays information 202B relating to the accuracy of the corrected in-vivo information based on, for example, the contribution degree of the high-accuracy reference value.

[0119] The information 202B relating to the accuracy of the corrected internal information is displayed as "A", for example, when there is a high-precision reference value, and is displayed as "B" when there is no high-precision reference value and only internal information measured with low accuracy by the simplified BIA body composition meter 100. Furthermore, even when "A" is displayed, the accuracy of the high-precision reference value, weight difference, and number of days elapsed are used as indicators, and the information is displayed as A1, A2, A3, etc., in order of the contribution of the high-precision reference value.

[0120] In this embodiment, when there is a high-precision reference value, the accuracy of the high-precision reference value is high, it is determined that "weight difference<α" and the number of days elapsed is determined to be "within z1 days", it is ranked as A1 and information 202B relating to the accuracy of the corrected internal body information is displayed.

[0121] In this way, the output unit 106 changes the appearance of the corrected in-vivo information 200B and the low-accuracy in-vivo information so as to distinguish them from each other, thereby allowing the user to know whether the accuracy of the in-vivo information has been improved. Also, the output unit 106 displays information related to the measurement accuracy based on the contribution of the high-accuracy reference value, allowing the user to know how much the accuracy of the measurement result has been improved.

[0122] In other words, the output unit 106 displays how much the measurement result has been improved in accuracy by inputting the high-precision reference value, and also shows the degree of contribution of the reference measurement method and the number of days elapsed to the high-precision reference value in a simple manner, so that the user can feel the improvement in accuracy. Therefore, it is possible to provide a highly accurate internal measurement system and program tailored to the individual.

[0123] [Operation of the body composition meter according to the second embodiment] The configuration of the body composition monitor according to the second embodiment is the same as that of the body composition monitor described above, and therefore the description thereof will be omitted. The operation of the body composition monitor according to the second embodiment differs from that of the first embodiment only in the first flow, and therefore only this difference will be described below.

[0124] 6 is a first flow chart showing the operation of the simplified BIA body composition analyzer 100 for determining a correction function according to a second embodiment of the present invention. The first flow according to the second embodiment is different from the first flow according to the first embodiment in that it is a flow for primarily adjusting high-precision internal information using an internal difference as an index in addition to a weight difference. When a user operates the simplified BIA body composition analyzer 100 to start the process of determining a correction function, the first flow according to the second embodiment starts.

[0125] First, the low-accuracy measurement unit 104 measures the internal body information of the user (step S302).

[0126] When the low-accuracy measurement unit 104 measures the internal body information of the user, the storage unit 110 stores a low-accuracy reference value (step S304).

[0127] When the memory unit 110 stores the low-accuracy reference value, the correction unit 112 determines whether or not there is a high-accuracy reference value stored in the memory unit 110 (step S306) and the weight difference (step S308).

[0128] If it is determined that "weight difference < α" with "high-precision reference value available" stored in memory unit 110 (step S306: Yes, step S308: Yes), correction unit 112 determines adjustment parameter Y0 according to the contribution of the high-precision reference value, adjusts the high-precision reference value by the primary adjustment "Y0 × high-precision reference value" (step S310), and the flow ends.

[0129] That is, when it is determined that "body weight difference<α", the body weight deviation is small, so it is considered that the change in body composition between the time the high-precision reference value was obtained and the time the correction method was decided is small, and it is determined that the contribution of the high-precision reference value is large. At this time, the correction unit 112 determines an adjustment parameter Y0 according to the contribution of the high-precision reference value, and adjusts the high-precision reference value by the primary adjustment "Y0 × high-precision reference value".

[0130] On the other hand, if it is determined that the "weight difference is not < α" with the "high-precision reference value available" stored in the memory unit 110 (step S306: Yes, step S308: No), the correction unit 112 again determines the weight difference (step S312). Then, it is determined that the "weight difference is < β" (step S312: Yes), or it is determined that the "internal difference ≧ γ" even if the "weight difference is not < β". If so (step S312: No, step S316: Yes), the correction unit 112 determines adjustment parameters Y1 to 5 according to the high-precision reference value, adjusts the high-precision reference value by the primary adjustment “Y1 to 5 × high-precision reference value” (step S314), and the flow ends.

[0131] In other words, even if the weight difference is not "<β", if it is judged that the internal difference is "≧γ", the weight discrepancy is observed. Therefore, although there is a change in body composition between when the high-precision reference value is obtained and when the correction method is determined, the contribution of the high-precision reference value is determined to be somewhat low in order to reflect the user's body composition, which is significantly different from the body composition estimated from the statistical value. In this case, the high-precision reference value is adjusted by the primary adjustment "Y1~5 x high-precision reference value" as when "weight difference < β".

[0132] On the other hand, if it is determined that the "high-precision reference value exists" stored in the storage unit 110 is not present (step S306: No), or if it is determined that the "high-precision reference value exists" but the "weight difference < α", the "weight difference < β", or the "internal difference ≧ γ" is not present (step S306: Yes s, step S308: No, step S312: No, step S316: No), the correction unit 112 does not correct the low-precision reference value using a correction function based on the primarily adjusted high-precision reference value (step S318), and the memory unit 110 simply stores the high-precision reference value as a reference value, and the flow ends.

[0133] In other words, when it is determined that there is a "high-precision reference value" but the body weight difference is not "<α", "<β", or "internal difference ≧γ", there is a large change in body composition between the time the high-precision reference value was obtained and the time the correction method was determined, and there is no need to reflect the user's body composition, which is significantly different from the body composition estimated from the statistical value. In this case, the correction unit 112 does not perform correction.

[0134] As described above, in the first flow according to the second embodiment, the contribution of the high-precision reference value is evaluated using the weight difference and the intra-body difference as indicators. Unlike the first flow according to the first embodiment, even when the weight deviation is large (weight difference ≧ β), when the intra-body difference is large (inter-body difference ≧ γ), the first-order Adjust the high-precision reference value by adjusting "Y1~5 x high-precision reference value". When the intracellular difference is small, no correction is performed.

[0135] In this way, in the first flow according to the second embodiment, unlike the first flow according to the first embodiment, it is possible to determine adjustment parameters that reflect the contribution of the high-precision reference value based on the difference in the individual's internal information (internal difference) in addition to the weight difference that is not due to the difference in the measurement method. Therefore, it is possible to provide a highly accurate internal measurement system and program that are tailored to the individual.

[0136] [Operation of the body composition monitor according to the third embodiment] The configuration of the body composition monitor according to the third embodiment is the same as that of the body composition monitor described above, and therefore the description thereof will be omitted. The operation of the body composition monitor according to the third embodiment differs from the second flow of the first embodiment described above only in the second flow, and therefore only this difference will be described below.

[0137] 7 is a second flow chart showing the operation of the simplified BIA body composition monitor 100 for determining a correction function according to the third embodiment of the present invention. The second flow according to the third embodiment is different from the second flow according to the first embodiment in that the first-adjusted high-precision reference value is further second-adjusted using the user's adjustment selection as an index in addition to the number of days elapsed. When the first flow ends, the second flow according to the third embodiment starts.

[0138] When the second flow starts, the correction unit 112 determines whether or not a first adjustment has been performed (step S402) and the number of days that have passed (step S404).

[0139] If it is determined that "primary adjustment is performed" and the number of days that have passed is "z 1 days or less" (step S402: Yes, step S404: Yes), the correction unit 112 does not perform the secondary adjustment (step S406), but determines a correction function based on the primarily adjusted high-precision reference value, corrects the low-precision reference value by this correction function, and the output unit 106 displays the low-precision in-vivo information as the corrected low-precision reference value as corrected in-vivo information (step S408). Then, the correction unit 112 stores the correction function and the corrected in-vivo information (step S410), and the flow ends.

[0140] That is, when the first adjustment is performed and the number of days that have passed is "within z days", it is considered that the change in body composition between the time when the high-precision reference value was obtained and the time when the correction method was decided is small, and it is determined that the contribution of the high-precision reference value is high. In this case, the correction unit 112 does not perform the second adjustment.

[0141] On the other hand, if it is determined that the elapsed days are not "within z1 days" with "primary adjustment" (step S402: Yes, step S404: No), the correction unit 112 determines the elapsed days again (step S412).

[0142] Is it determined that the elapsed days are "within z2 days" (step S412: Yes)? Although the elapsed days are not "within z2 days" and an "alert is presented" to prompt the user to measure the high-precision reference value (step S418), if it is determined that the user has made an "adjustment selection" (step S420: Yes), the correction unit 112 determines adjustment parameters Y0 to 5, a, and b according to the contribution degree, and performs a secondary adjustment of "(a × Y0 to 5 × high-precision reference value + b × low-precision reference value) / 2" to adjust the high-precision reference value to a higher precision (step S414). Then, the correction unit 112 corrects the low-precision reference value with a correction function based on the secondarily adjusted high-precision reference value, and the output unit 106 displays the low-precision body information as the corrected low-precision reference value as corrected body information (step S416). The storage unit 110 stores the correction function and the corrected body information (step S410), and the flow ends.

[0143] That is, if it is determined that although the elapsed days are not "within z2 days" with "primary adjustment", the user who has been "presented with an alert" has made an "adjustment selection", the correction unit 112 determines adjustment parameters Y0 to 5, a, and b according to the contribution degree of the high-precision reference value, and adjusts the high-precision reference value by a secondary adjustment of "(a × Y0 to 5 × high-precision reference value + b × low-precision reference value) / 2".

[0144] On the other hand, if it is determined that "primary adjustment has been performed" (step S402: No), or if "primary adjustment has been performed" and the number of days that have passed is neither "within z1 days" nor "within z2 days", and an "alert has been presented" to encourage the user to measure a high-precision reference value but the user has not "selected adjustment" (step S402: Yes, step S404: No, step S412: No, step S418, step S420: No), the correction unit 112 does not correct the low-precision reference value using a correction function, the output unit 106 displays the low-precision in-vivo information as a low-precision reference value (step S422), the memory unit 110 stores the low-precision in-vivo information as a low-precision reference value (step S424), and the flow ends.

[0145] That is, when "primary adjustment was performed" and the number of days that have passed is neither "within z1 days" nor "within z2 days", and the user has not selected "adjustment selection", it is assumed that the change in body composition between the time the high-precision reference value was obtained and the time the correction method was determined is large, and it is determined that the contribution of the high-precision reference value is small. In this case, the correction unit 112 does not perform correction.

[0146] As described above, in the second flow according to the third embodiment, the contribution of the high-precision reference value is evaluated using the number of days elapsed and the adjustment selection of the user as indicators. Unlike the second flow according to the first embodiment, if it is determined that the user who has been "presented with an alert" has made an "adjustment selection" even though the number of days has passed z2 days, the low-precision reference value is corrected by a correction function based on the second-adjusted high-precision reference value, the low-precision in-vivo information as the corrected low-precision reference value is displayed as the corrected in-vivo information, and the correction function and the corrected in-vivo information are stored. On the other hand, if it is determined that the user who has been "presented with an alert" has not made an "adjustment selection", the low-precision in-vivo information is displayed as the low-precision reference value without correcting the low-precision in-vivo information as the low-precision reference value by the correction function, and the low-precision in-vivo information is stored as the low-precision reference value.

[0147] Thus, in the second flow of the third embodiment, unlike the second flow of the first embodiment, the secondary adjustment can be determined based on the user's selection in addition to the number of days elapsed, thereby providing a highly accurate internal measurement system and program tailored to the individual.

[0148] Furthermore, in the second flow of the third embodiment, unlike the second flow of the first embodiment, an alert is sent to prompt the user to measure a new high-precision reference value, motivating the user to improve the accuracy of the internal measurement system, thereby making it possible to provide a highly accurate internal measurement system and program tailored to the individual.

[0149] In the second flow according to the third embodiment, the timing for "presenting an alert" is set to "within z2 days" from the time of acquisition of the high-precision reference value. This number of days "within z2 days" can be changed depending on the measurement method of the high-precision reference value. For example, when measuring the high-precision reference value using a body composition measurement (estimation) method with high measurement accuracy of internal information such as DXA, the measurement method is not one that can be used frequently, so z2 may be set to a relatively long number of days. On the other hand, when measuring the high-precision reference value using a high-precision BIA body composition analyzer such as a multi-frequency multi-electrode BIA body composition analyzer, the measurement method can be used frequently compared to when measuring the high-precision reference value using DXA, so z2 may be set to a relatively short number of days.

[0150] As described above, in any of the first, second and third embodiments of the present invention, the user can know highly accurate internal body information, despite the simple measurement using the simplified BIA body composition meter 100. Here, the form of the simplified BIA body composition meter 100 may be any form, such as a flat type, a stand type, or a card type having an input unit 102, a low-accuracy measurement unit 104 and an output unit 106 as shown in Fig. 8, and the simple measurement may be any measurement that has a lower measurement accuracy of internal body information than the body composition measurement (estimation) method, such as a simple measurement of both feet or a simple measurement of both hands.

[0151] [Variation 1] The flow of the above embodiment is composed of the first flow and the second flow, but the second flow may be omitted and only the first flow may be used. In this case, the adjustment parameter is determined based only on the weight difference between the time when the high-precision reference value is obtained and the time when the correction method is determined, and the high-precision reference value is adjusted to determine the correction function.

[0152] Explaining with reference to Fig. 3, in the first flow, the correction unit 112 determines a correction function based on the first-adjusted high-precision reference value and the low-precision in-vivo information, and corrects the low-precision in-vivo information by this correction function. Then, this corrected low-precision in-vivo information is displayed as corrected in-vivo information, and the correction function and the corrected in-vivo information are stored. This step can be provided as a step following each of step S110 and step S114.

[0153] The low-accuracy in-vivo information as the corrected low-accuracy reference value may be an average value of the primarily adjusted high-accuracy reference value and the low-accuracy in-vivo information as the low-accuracy reference value corrected by the correction function.

[0154] [Variation 2] The flow of the above embodiment is composed of the first flow and the second flow, but only the second flow may be used without the first flow. In this case, the adjustment parameters are determined based only on the number of days that have passed between the time when the high-precision reference value was obtained and the time when the correction method was determined, and the high-precision reference value is adjusted to determine the correction function.

[0155] Explaining with reference to Fig. 4, when the user operates the simplified BIA body composition monitor 100 to start the process of determining the correction function, the second flow starts. When the second flow starts, first, a step of measuring the user's internal body information by the low-accuracy measuring unit 104 and a step of storing the low-accuracy internal body information by the memory unit 110 are performed. Then, instead of the step of the correction unit 112 determining whether or not a primary adjustment has been performed (step S202), the correction unit 112 determines whether or not a high-accuracy reference value is stored in the memory unit 110. After that, the steps from step S204 to the end can be determined.

[0156] [Variation 3] In addition, in the above embodiment, the correction unit 112 obtained corrected in-vivo information by correcting the low-accuracy in-vivo information obtained by the low-accuracy measurement unit 104 with a correction function based on the high-accuracy reference value and the low-accuracy reference value, but the method of obtaining the corrected in-vivo information is not limited to this.

[0157] The correction unit 112 may correct the algorithm used by the low-accuracy measurement unit 104 based on the high-accuracy reference value and the low-accuracy reference value. The low-accuracy measurement unit 104 inputs the measurement value into the algorithm corrected by the correction unit 112, thereby acquiring corrected in-vivo information.

[0158] For example, when the predetermined algorithm is a regression equation, the correction unit 112 corrects the predetermined regression equation that outputs low-precision in-vivo information when a measured value is input to a regression equation that outputs an adjusted high-precision reference value when a measured value at the time of determining the correction method is input. The memory unit 110 stores the corrected regression equation, and in subsequent low-precision measurements, the low-precision measurement unit 104 inputs the measured value into the corrected regression equation to obtain corrected in-vivo information. When a new high-precision reference value is obtained, the regression equation can be updated.

[0159] In this way, the correction unit 112 may correct the low-accuracy in-vivo information calculated by a predetermined algorithm in the low-accuracy measurement unit 104 using a correction function, as in the above embodiment, or may correct the algorithm itself that calculates the low-accuracy in-vivo information from the measurement value in the low-accuracy measurement unit 104, as in the above modified example.

[0160] In addition, the correction unit 112 may correct the predetermined algorithm itself based on the corrected in-vivo information and the low-accuracy in-vivo information calculated by the predetermined algorithm after acquiring the corrected in-vivo information once. Once the algorithm is corrected, the result of the low-accuracy measurement measured thereafter approaches the corrected in-vivo information. Therefore, once the algorithm is corrected, the difference between the corrected in-vivo information and the result of the low-accuracy measurement becomes smaller, and a highly accurate in-vivo measurement system and program tailored to an individual can be provided.

[0161] [Variation 4] In the above embodiment, the correction function is set by one measurement by the low-accuracy measuring unit 104, but the correction function may be set after multiple measurements. For example, the low-accuracy measuring unit 104 may perform measurements twice, on the first day and the second day, and the correction function may be set using the average of the low-accuracy in-vivo information as the low-accuracy reference value on the first day and the second day. In this case, the correction function may be set at the time of the measurement by the low-accuracy measuring unit 104 on the second day. In this way, by setting the correction function after multiple measurements by the low-accuracy measuring unit 104, the correction function can be set using the low-accuracy in-vivo information that takes variability into consideration. Therefore, it is possible to provide a highly accurate in-vivo measurement system and program tailored to an individual. [Explanation of symbols]

[0162] 100...Simple BIA body composition meter 102 Input section 104...Low precision measurement section 106 Output section 108...Control section 110...Storage section 112... Correction unit 200A, 200B: Corrected internal body information 202B Information on the accuracy of corrected in vivo information

Claims

1. A storage unit that stores the measurement values ​​of the plurality of types of body composition obtained by the measurement of the first accuracy as reference values; a low-accuracy measurement unit that obtains a low-accuracy body composition value by inputting a measurement value obtained by a measurement with a second accuracy lower than the first accuracy into a predetermined algorithm; a correction unit that corrects the algorithm or the low-precision body composition value based on the reference value stored in the storage unit and a degree of importance given to the reference value; an output unit that outputs, as a corrected body composition value, the low-precision body composition value acquired by the low-precision measurement unit using the algorithm corrected by the correction unit, or the low-precision body composition value acquired by the low-precision measurement unit and corrected by the correction unit; Equipped with An internal body measurement system, wherein the degree is determined based on a period of time between performing the first accuracy measurement and correcting the algorithm or the low accuracy body composition value, and differs depending on the type of body composition.

2. The internal body measurement system according to claim 1 , wherein the degree is determined according to a contribution degree of the reference value stored in the memory unit to the low-accuracy body composition value acquired by the low-accuracy measurement unit.

3. The internal body measurement system of claim 1 or 2, wherein the degree is also determined based on the difference between the reference value and the low-accuracy body composition value obtained by the low-accuracy measurement unit when correcting the algorithm or the low-accuracy body composition value.

4. The internal body measurement system according to claim 1 , wherein the correction unit corrects the algorithm or the low-accuracy body composition value based on a user's selection.

5. The internal body measurement system according to claim 1 , wherein the storage unit stores the corrected algorithm or a correction function for correcting the low-accuracy body composition value, and the corrected body composition value.

6. The internal body measurement system according to claim 1 , further comprising an input unit that receives a body composition measurement value obtained by the measurement with the first accuracy and inputs it as the reference value.

7. The internal body measurement system according to any one of claims 1 to 6, wherein the output unit changes its appearance to display the corrected body composition value and the low-precision body composition value obtained by inputting the measurement value in the low-precision measurement unit into the specified algorithm so as to be distinguishable from each other.

8. The internal measuring system according to claim 1 , wherein the output section displays information relating to accuracy of the corrected body composition value based on the degree.

9. The internal body measurement system according to claim 1 , wherein the output unit displays an alert based on a period of time from when the measurement of the first accuracy is performed to when the low accuracy body composition value is acquired.

10. An in-vivo measurement program for causing a computer to function as the storage unit, the low-accuracy measurement unit, the correction unit, and the output unit constituting the in-vivo measurement system according to any one of claims 1 to 9.

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