Pest repellent

Abstract

To provide a pest repellent, which is particularly suitable for direct application to a target pest.SOLUTION: A pest repellent is prepared that contains a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid as an active ingredient. Such a pest repellent can be charged into various containers; may be charged into a spray-type container; or may be provided as an aerosol-type.SELECTED DRAWING: None

Description

Technical Field

[0001] The present invention relates to a pest repellent. More specifically, the present invention relates to a pest repellent for preventing pests such as mites from approaching humans, clothing, furniture, etc.

Background Art

[0002] Pests such as mites are known to transmit diseases that cause serious symptoms in humans and to be causative substances of allergies. For these pests, insecticides that use insecticidal components to kill and control them, and repellents that prevent pests from approaching, are used.

[0003] Regarding insecticides, there are concerns about the safety of consumers with respect to the chemical components contained therein. On the other hand, as a repellent that can be avoided even if pests do not die and has relatively few safety concerns, for example, in Patent Document 1 and Patent Document 2, copaiba oil, and spice-based essential oils such as clove and nutmeg, and repellents containing caryophyllene contained in natural products such as orange oil and lemon oil are disclosed.

Prior Art Documents

Patent Documents

[0004]

Patent Document 1

Patent Document 2

Summary of the Invention

Problems to be Solved by the Invention

[0005] However, there is a need for a further pest repellent that is highly safe and can surely repel pests.

[0006] An object of the present invention is to provide a pest repellent that can be directly applied to a pest repellent target and has a repellent effect.

Means for Solving the Problem

[0007] As a result of intensive studies to solve this problem, the inventors of the present invention have found that by containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid as an active ingredient, it can be directly applied to the target of pest repellency, and a pest repellent with good permeability can be prepared, thus completing the present invention.

[0008] That is, the present invention provides a pest repellent as described below. Item 1. A pest repellent containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid as an active ingredient. Item 2. The pest repellent according to Item 1, further containing an alcohol-based solvent. Item 3. The pest repellent according to Item 1 or 2, wherein the linear C1-4 alkyl ester of stearic acid is butyl stearate, and the C1-2 alkyl ester of myristic acid is methyl myristate. Item 4. A pest repellent containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid as an active ingredient and filled in a spray-type container. Item 5. An aerosol pest repellent comprising an aerosol stock solution for pest repellency containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid as an active ingredient and a propellant. Item 6. The aerosol pest repellent according to Item 5, wherein the aerosol stock solution further contains an alcohol-based solvent. Item 7. The aerosol pest repellent according to Item 5 or 6, wherein the mass ratio of the stock solution to the propellant (stock solution / propellant) is 10 / 90 to 50 / 50. Item 8. The pest repellent according to any one of claims 1 to 7 for directly spraying on the object to be repelled by pests. Claim 9. The pest repellent according to any one of claims 1 to 8, wherein the pest is a mite.

[0009] Furthermore, the present invention provides the following method. Claim 10. A pest repellent method including a step of directly spraying the pest repellent according to any one of claims 1 to 9 on the object to be repelled by pests.

Effect of the Invention

[0010] According to the present invention, it is possible to provide an excellent pest repellent with high safety.

Brief Description of the Drawings

[0011]

Figure 1

Modes for Carrying Out the Invention

[0012] In this specification, the unit of content "w / v%" is synonymous with "g / 100ml".

[0013] [Pest Repellent] The pest repellent of the present invention is a pest repellent containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid as an active ingredient.

[0014] (Active Ingredient) When referred to as an active ingredient in this specification, it has the same meaning as the ingredient that exhibits the effect of repelling pests.

[0015] Here, examples of the linear C1-4 alkyl ester of stearic acid include methyl stearate, ethyl stearate, propyl stearate, or butyl stearate, among which butyl stearate is particularly preferred.

[0016] Examples of the C1-2 alkyl esters of myristic acid include methyl myristate and ethyl myristate, among which methyl myristate is particularly preferred.

[0017] In the pest repellent of the present invention, the total content of the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid relative to the total amount of the pest repellent is preferably 0.01 w / v% or more, more preferably 0.1 w / v% or more, further preferably 0.3 w / v% or more, and particularly preferably 0.5 w / v% or more. The total content of the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid relative to the total amount of the pest repellent is preferably 50 w / v% or less, more preferably 30 w / v% or less, further preferably 20 w / v% or less, and particularly preferably 10 w / v% or less. Here, the content relative to the total amount of the pest repellent refers to the ratio of the component during application. For example, in the case of an aerosol form, it refers to the ratio relative to the total amount including the stock solution and the propellant, and in the case of other than the aerosol form, it refers to the ratio in the whole liquid.

[0018] In the pest repellent of the present invention, the content of butyl stearate relative to the total amount of the pest repellent is preferably 0.01 - 50 w / v%, more preferably 0.1 - 30 w / v%, further preferably 0.3 - 20 w / v%, and even more preferably 0.5 - 10 w / v%.

[0019] In the pest repellent of the present invention, the content of methyl myristate relative to the total amount of the pest repellent is preferably 0.01 - 50 w / v%, more preferably 0.1 - 30 w / v%, further preferably 0.3 - 20 w / v%, and even more preferably 0.5 - 10 w / v%.

[0020] When the pest repellent of the present invention is in the form of an aerosol, the total content of the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid in the aerosol stock solution is preferably 1.0 w / v% or more, more preferably 5.0 w / v% or more, still more preferably 10.0 w / v% or more, and particularly preferably 15.0 w / v% or more. The total content of the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid relative to the total amount of the pest repellent is preferably 80.0 w / v% or less, more preferably 70.0 w / v% or less, still more preferably 50.0 w / v% or less, and particularly preferably 40.0 w / v% or less.

[0021] When the pest repellent of the present invention is in the form of an aerosol, the content of butyl stearate in the aerosol stock solution is preferably 5.0 to 70.0 w / v%, more preferably 10.0 to 50.0 w / v%, and still more preferably 20.0 to 40.0 w / v%.

[0022] When the pest repellent of the present invention is in the form of an aerosol, the content of methyl myristate in the aerosol stock solution is preferably 5.0 to 70.0 w / v%, more preferably 10.0 to 50.0 w / v%, and still more preferably 20.0 to 40.0 w / v%.

[0023] (Solvent) In addition to the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid, it is also preferable that the pest repellent of the present invention contains a solvent. The solvent used in the present invention is not limited, and for example, alcohol solvents such as methanol, ethanol, butanol, 1-propanol, 2-propanol, and 1-butanol; or ketone solvents such as acetone, methyl ethyl ketone, diethyl ketone, and cyclohexanone can be used. Among these, it is preferable to use an alcohol solvent as the solvent, and ethanol is particularly preferable. In particular, when the pest repellent of the present invention is in the form of an aerosol, an alcohol solvent is preferably used for preparing the aerosol stock solution.

[0024] From the perspective of exerting the effects of the present invention, the content of the solvent relative to the total amount of the pest repellent of the present invention is preferably 10 w / v% or more, more preferably 20 w / v% or more, and particularly preferably 30 w / v% or more. The content of the solvent relative to the total amount of the pest repellent is preferably 90 w / v% or less, more preferably 85 w / v% or less, and particularly preferably 75 w / v% or less. When the pest repellent of the present invention is in the form of an aerosol, it is preferable that the proportion of the solvent in the aerosol stock solution is within these values.

[0025] When the pest repellent of the present invention contains ethanol, the content of ethanol relative to the total amount of the pest repellent is preferably 10 - 90 w / v%, more preferably 20 - 85 w / v%, still more preferably 30 - 80 w / v%, and even more preferably 50 - 75 w / v%. When the pest repellent of the present invention is in the form of an aerosol, it is preferable that the proportion of ethanol in the aerosol stock solution is within such values.

[0026] (Water) The pest repellent of the present invention can be formulated with water, or can be in the form of a composition or aerosol that does not contain any water at all. Examples of such water include purified water such as ion-exchanged water, ordinary tap water, industrial water, and the like. When the pest repellent contains water, the content of water relative to the total amount of the pest repellent is preferably 5 w / v% or more, more preferably 10 w / v% or more, and particularly preferably 20 w / v% or more. The content of water relative to the total amount of the pest repellent is preferably 95 w / v% or less, more preferably 85 w / v% or less, and particularly preferably 80 w / v% or less.

[0027] (Pest) Pests referred to in this specification include, but are not limited to, in particular, sanitary pests such as mites (e.g., Dermatophagoides spp.), mosquitoes, midges, houseflies, flour beetles, and bugs. Particularly preferred pest to be repelled is the mite.

[0028] (pH) The pest repellent of the present invention preferably has a liquid property of pH 5 to 9 from the viewpoints of the stability of the components, particularly the damage or stain on the target when applied to the pest repellent target, or safety. More preferably, it is a neutral pest repellent with a pH of 5.5 to 8.0. The pH of the pest repellent can be measured at 20 ° C using a commercially available pH meter (for example, F-52 (registered trademark) type manufactured by Horiba, Ltd.). When the pest repellent does not contain water, the value measured by diluting the pest repellent 20 times with purified water is taken as the pH.

[0029] (Other components) As long as the effects of the present invention are not inhibited, optional components other than the linear C1-4 alkyl esters of stearic acid and / or the C1-2 alkyl esters of myristic acid may be appropriately blended in the pest repellent of the present invention. For example, the optional components include other pest repellent components, pH adjusters, surfactants, silicone compounds, chelating agents, recontamination preventers, polymers, preservatives, antibacterial agents, bactericides, natural product extracts, dispersants, antioxidants, thickeners, thinning agents, stabilizers, deodorants, fragrances, dyes, etc., other than the linear C1-4 alkyl esters of stearic acid and / or the C1-2 alkyl esters of myristic acid.

[0030] Examples of other pest repellent components include N, N-diethyl-m-toluamide (DEET), di-n-butyl succinate, hydroxyanisole, rotenone, ethyl-butylacetylaminopropionate, icaridin (picaridin), p-menthane-3,8-diol, ethyl 3- [acetyl (butyl) amino] propionate, 1-methylpropyl 2- (2-hydroxyethyl) piperidine-1-carboxylate, etc. These pest repellent components may be used in combination. Alternatively, a pest repellent that does not contain any such other repellent components can also be used.

[0031] Examples of the pH adjuster include, but are not limited to, citric acid, sodium citrate, sodium hydrogen carbonate, triethanolamine, ammonia, potassium hydroxide, sodium hydroxide, etc.

[0032] (Surfactant) Examples of the surfactant include polyoxyethylene alkyl ether, polyoxyethylene fatty acid alkyl ester, polyoxyethylene alkylamine, alkyl polyglucoside, polyoxyethylene hydrogenated castor oil, and the like.

[0033] (Use, etc.) The pest repellent of the present invention can be applied so as to spread in space, but preferably, it can also be directly applied to the object to be repelled from pests. Here, the application is not limited, but spraying with a spray or the like is exemplified.

[0034] Here, the objects to be repelled from pests are not limited, but include futons, cloth sofas, clothes, fiber products such as carpets, tatami mats, walls, wooden furniture (desks, bookshelves, wardrobes, etc.), and the like.

[0035] The pest repellent of the present invention can be used once or several times a day at known or conventional usage amounts and dosages according to the use and the like. Alternatively, it can also be used once a week or once every two weeks. For example, when applying to an object to be repelled from pests, it can be directly applied to the object from a distance of about 1 to 150 cm, preferably about 20 to 100 cm, from the surface thereof.

[0036] Regarding the usage amount of the repellent of the present invention, from the viewpoint of the repellent effect, for example, when the object to be repelled from pests is a fiber product such as a cloth sofa or a futon, the amount of the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid per 100 cm 2 is preferably 0.01 mg or more, more preferably 0.1 mg or more, and even more preferably 1 mg or more. The amount of the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid per 100 cm of the fiber product 2 is preferably 30 mg or less, more preferably 20 mg or less, and even more preferably 10 mg or less from the viewpoint of preventing stains on the fiber.

[0037] When the repellent of the present invention is applied as an aerosol, the amount used is not limited, but preferably about 0.05 to 0.5 ml per push, more preferably about 0.1 to 0.3 ml.

[0038] When the pest repellent of the present invention is applied to a pest repellent target in such an amount, for example, when applied to a textile product, the duration of the repellent effect can be long. For example, the duration is preferably at least about 7 days, more preferably about 14 days, and can also be expected to be about 20 days.

[0039] (Container, etc.) The pest repellent of the present invention is preferably used in an aerosol form, a pump form (including a spray form), etc., although not limited thereto. Therefore, it is preferably filled and used in an aerosol can, an aerosol resin container, a hand spray container, a pump type container, etc.

[0040] In the case of an aerosol form, the pest repellent of the present invention and a propellant can be enclosed in an aerosol container and used. Examples of the propellant include liquefied petroleum gas (propane, normal butane, isobutane, etc.), dimethyl ether, normal pentane, isopentane, 1,3,3,3 - tetrafluoropropene, nitrogen gas, carbon dioxide gas, nitrous oxide gas, etc. These can be used alone or in combination.

[0041] On the other hand, in the case of a spray form, the pest repellent of the present invention can be enclosed in a container such as a hand spray and used.

[0042] In both the aerosol form and the spray form, the average particle diameter of the droplets sprayed in a mist form is not particularly limited. For example, the 50% average particle diameter at a position 30 cm away from the nozzle is about 10 to 1000 μm.

[0043] In the case of an aerosol, the mass ratio of the liquid to the propellant (stock solution / propellant) is preferably 10 / 90 to 50 / 50, more preferably 10 / 90 to 30 / 70.

[0044] [Method for preventing stickiness] The present invention also relates to a method for preventing stickiness when the pest repellent containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid is applied to a pest repellent target. In the method for preventing stickiness of the present invention, the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid and their contents shall conform to the content described in the above-mentioned pest repellent. Also, the solvent, pH, other optional components, their contents, and the container for containing them may conform to the content described in the above-mentioned pest repellent.

[0045] [Method for promoting penetration] The present invention also relates to a method for promoting penetration when the pest repellent containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid is applied to a pest repellent target. Preferably, the pest repellent target is a textile product. In the method for promoting penetration of the present invention, the linear C1-4 alkyl ester of stearic acid and / or the C1-2 alkyl ester of myristic acid and their contents shall conform to the content described in the above-mentioned pest repellent. Also, the solvent, pH, other optional components, their contents, and the container for containing them may conform to the content described in the above-mentioned pest repellent.

[0046] [Method for repelling pests] The present invention also relates to a method for repelling pests, which includes a step of directly spraying a pest repellent containing a linear C1-4 alkyl ester of stearic acid and / or a C1-2 alkyl ester of myristic acid onto a pest repellent target. In the pest repellent method of the present invention, regarding the linear C1-4 alkyl esters of stearic acid and / or the C1-2 alkyl esters of myristic acid and their contents, they shall conform to the contents described in the above-mentioned pest repellent. Also, regarding the solvent, pH, other optional components, their contents, and the containers for accommodating them, they may conform to the contents described in the above-mentioned pest repellent.

Examples

[0047] Next, the present invention will be specifically described by way of examples, but the present invention is not limited to the following examples. In addition, the unit of each component amount in the table is w / v% unless otherwise specified in the table.

[0048] [1] Repellent efficacy test Regarding the components shown in Table 1, the efficacy was evaluated in accordance with the intrusion prevention method of the fiber product anti-mite performance test method of JIS L 1920.

[0049] The components in Table 1 were prepared to be 5.0 w / v% with acetone. The prepared liquid was impregnated into a circular filter paper 1 with a diameter of about 40 mm so that it was 0.2 ml per 1.62 m 2 (per tatami mat side) and spread on a petri dish with a diameter of 40 mm (the first petri dish 2).

[0050] Next, a mite medium 3 containing Dermatophagoides pteronyssinus was evenly spread in a second petri dish 4 with a larger diameter than the first petri dish 2, and mites equivalent to 10,000 were placed. The first petri dish 2 was placed on top of the center of the second petri dish 4 and left standing at a temperature of 23 to 27 °C and a humidity of 70 to 80% RH for 24 hours. Then, the number of mites invading from the second petri dish 4 into the first petri dish 2 was counted. And, taking the specimen impregnated with only acetone as the untreated group, the repellency was determined from the following formula. Here, the number of invading mites in the untreated group, the number of invading mites in the treated group, and the number of invading mites in the untreated group are all the total numerical values in n = 3 (3 tests). (Formula) Repellency (%) = [Number of invading mites in the untreated group - Number of invading mites in the treated group] / Number of invading mites in the untreated group × 100 (1)

[0051] The results are shown in Table 1.

[0052] [Table 1]

[0053] As a result of the efficacy test, it was found that the composition of the example had a significant pest repellent effect compared to the composition of the reference example.

[0054] [2] Repellent efficacy persistence test An efficacy test was conducted in the same manner as the above [1] repellent efficacy effect test. However, the test specimens were allowed to stand still for 14 days and 20 days under the environment of 25 ± 2°C and 65 ± 5% RH, and the repellent test was carried out. Thereafter, the repellency rate was determined in the same manner as the [1] repellent efficacy effect test. The results are shown in Table 2 and Table 3.

[0055] [Table 2]

[0056] [Table 3]

[0057] As a result, even after 14 days, a high efficacy of 70% or more was confirmed in the examples. On the other hand, in the reference examples, the results were low at 50% or less. Furthermore, after 20 days, in the examples, although the efficacy had decreased, 50% or more of the efficacy was confirmed. On the other hand, in the reference examples, the effect after 20 days had further decreased.

[0058] [3] Penetration evaluation test The composition of the example or reference example was used as the stock solution and filled into a 25 mL pressure-resistant aluminum can. Further, liquefied petroleum gas (LPG) was filled to about 2.5 MPa. Two pieces of cloth (cotton) cut to 20 cm × 20 cm were prepared and overlapped. Spraying was carried out once from a height of 30 cm. After 24 hours in an environment of 25 ± 2°C and 65 ± 5% RH, the lower cloth was taken out as the specimen. The specimen was cut to a diameter of 40 mm and spread in a 40 mm petri dish, and the repellent effect was confirmed. Here, the test method for the repellent effect was carried out in the same manner as [1].

[0059]

Table 4

[0060] It is considered that the chemical solution sprayed on the upper cloth penetrated the lower cloth and the effect appeared. In the examples, a high effect of 70% or more was confirmed, but in the reference examples, no repellent effect was confirmed. The composition of the examples was shown to be excellent in permeability.

Claims

**Claim 1**: An acarid repellent containing butyl stearate as an active ingredient and further containing an alcoholic solvent (provided that it excludes an aerosol insecticide for coating, which is composed of 30 to 55% by weight of an insecticidal stock solution containing 0.05 to 10% by weight of an insecticidal component, 1.0 to 30% by weight of a higher fatty acid ester compound or a vegetable oil mainly composed of a higher fatty acid glyceride, and 60 to 99% by weight of a paraffinic solvent as main components, and 45 to 70% by weight of a propellant). **Claim 2**: The acarid repellent according to Claim 1, which contains butyl stearate as an active ingredient and is filled in a spray-type container. **Claim 3**: An aerosol acarid repellent composed of an aerosol stock solution containing butyl stearate as an active ingredient and a propellant (provided that it excludes an aerosol insecticide for coating, which is composed of 30 to 55% by weight of an insecticidal stock solution containing 0.05 to 10% by weight of an insecticidal component, 1.0 to 30% by weight of a higher fatty acid ester compound or a vegetable oil mainly composed of a higher fatty acid glyceride, and 60 to 99% by weight of a paraffinic solvent as main components, and 45 to 70% by weight of a propellant). **Claim 4**: The aerosol acarid repellent according to Claim 3, wherein the aerosol stock solution further contains an alcoholic solvent. **Claim 5**: **Claim 6**: The aerosol acarid repellent according to Claim 3 or 4, wherein the mass ratio of the stock solution to the propellant (stock solution / propellant) is 10 / 90 to 50 / 50. **Claim 7**: The acarid repellent according to any one of Claims 1 to 5, which is for directly spraying on a pest-repellent target.

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