Pesticide components

Abstract

A pesticidal composition comprising: (i) 25 to 35% by weight of spiropyridione; (ii) 20 to 30% by weight of acetamiprid; and (iii) 2.5 to 10% by weight of a buffering agent (comprising, based on the total weight of the composition, (a) 2 to 7% by weight of an alkali metal sulfate or alkaline earth metal sulfate, and (b) 0.1 to 5% by weight of an organic acid).

Description

Technical Field

[0001] The present invention relates to a composition comprising a combination of insecticidal active ingredients, the preparation of such a composition, and a method of using such a composition to control pests in crops of useful plants.

Background Art

[0002] An insecticidal composition containing a combination of the insecticidal active ingredient spirodiclofen and another active ingredient is known, for example, from WO 2013 / 107793. However, in certain compositions for use in controlling insects on crop plants, the chemical instability of the active ingredient (e.g., spirodiclofen) that results in a loss of insecticidal ability can be a problem. Therefore, there remains a strong motivation to develop insecticidal compositions in which the active ingredient components maintain long-term chemical stability for practical purposes.

Summary of the Invention

Means for Solving the Problems

[0003] According to the present invention, (i) 25 to 35% by weight of spirodiclofen; (ii) 20 to 30% by weight of acetamiprid; and (iii) 2.5 to 10% by weight of a buffer (based on the total weight of the composition, (a) 2 to 7% by weight of an alkali metal sulfate and / or an alkaline earth metal sulfate, and (b) 0.1 to 5% by weight of an organic acid is included)), there is provided a pesticidal composition comprising the same.

[0004] The pest-killing compositions of the present invention, for practical purposes, also maintain acceptable crop safety (plant toxicity) results while possessing highly advantageous levels of activity in controlling pests in useful plant crops after application to leaves or soil. Activity means that the compositions of the present invention can kill or control insects, delay insect growth or reproduction, reduce insect populations, and / or reduce plant damage caused by insects.

[0005] Furthermore, surprisingly, it has been found that for the purposes of the present invention, the addition of an organic acid (e.g., citric acid) to certain compositions containing spiropidione and acetamiprid significantly improves the chemical stability of the spiropidione active ingredient component and, therefore, the useful shelf life of compositions containing these two active ingredients.

[0006] Furthermore, the present invention provides an aqueous composition comprising a pest-killing composition according to the present invention, which optionally further comprises one or more types of adjuvants or carriers.

[0007] Furthermore, the present invention provides a (non-therapeutic) method for combating and controlling pests, which includes applying the composition according to the present invention to pests, to the habitats of pests, or to useful plant crops that are susceptible to attacks by pests. [Modes for carrying out the invention]

[0008] Spiropidione ([3-(4-chloro-2,6-dimethylphenyl)-8-methoxy-1-methyl-2-oxo-1,8-diazaspiro[4.5]deca-3-en-4-yl]ethyl carbonate; CAS number: 1229023-00-0) is known, in particular, from International Publication Nos. 2010 / 066780, 2018 / 114648, and 2018 / 114649. Acetamiprid ((1E)-N-[(6-chloro-3-pyridyl)methyl]-N'-cyano-N-methylacetamidine; CAS number: 135410-20-7) is known, in particular, from the specification of European Patent No. 0456826. Certain pest-killing mixtures containing spiropidione and acetamiprid as active ingredients are publicly known from International Publication No. 2013 / 107793.

[0009] Preferably, the composition according to the present invention comprises (i) 28-32% by weight of spiropidione and (ii) 22-26% by weight of acetamiprid as active ingredient components for killing pests, more preferably (i) 29-31% by weight of spiropidione and (ii) 23-25% by weight of acetamiprid.

[0010] The composition according to the present invention contains spiropidione and acetamiprid as active ingredients for killing pests, respectively, in a weight ratio of 5:6 to 7:4, preferably 1:1 to 3:2.

[0011] Preferably, the composition according to the present invention comprises 4.5 to 8% by weight of a buffering agent, the buffering agent comprising 4 to 6% by weight of an alkali metal sulfate and 0.5 to 2.5% by weight of an organic acid, relative to the total composition. Most preferably, the composition according to the present invention comprises 4.5 to 6.5% by weight of a buffering agent, the buffering agent comprising 4 to 6% by weight of an alkali metal sulfate and 0.5 to 1.5% by weight of an organic acid, relative to the total composition.

[0012] More preferably, the composition according to the present invention comprises 4.5 to 8% by weight of a buffering agent, wherein the buffering agent comprises 4 to 6% by weight of an alkali metal sulfate and 0.5 to 2.5% by weight of citric acid, relative to the total composition. Most preferably, the composition according to the present invention comprises 4.5 to 6.5% by weight of a buffering agent, wherein the buffering agent comprises 4 to 6% by weight of an alkali metal sulfate and 0.5 to 1.5% by weight of citric acid, relative to the total composition.

[0013] The buffering component of the composition of the present invention may include alkali metal sulfates or alkaline earth metal sulfates, or a combination of alkali metal sulfates and alkaline earth metal sulfates. Preferably, the alkali metal sulfate used in the composition of the present invention is potassium sulfate or sodium sulfate, most preferably sodium sulfate.

[0014] Preferably, the organic acid used in the present invention is an organic acid containing one, two, or three carboxylic acid groups. More preferably, the organic acid is a tricarboxylic acid (i.e., containing three carboxylic acid groups). Even more preferably, the organic acid is citric acid or a salt thereof, for example, a sodium or potassium salt of citric acid (sodium citrate or potassium citrate). Most preferably, the organic acid is citric acid.

[0015] In a preferred embodiment, the composition of the present invention, in terms of the total weight of the composition (i.e., up to 100% by weight): (iv) 15-20% by weight of one or more dispersants; (v) 1-5% by weight of an antifoaming agent; and (vi) 15-30% by weight of filler (optionally, the filler may be added to the total weight of the composition) (c) 5-15% by weight of polymethylurea resin filler, and (d) 10-15% by weight lactose monohydrate filler (including) and further including.

[0016] In other preferred embodiments, the composition of the present invention may contain 1 to 3% by weight of an antifoaming agent, preferably 1.5 to 2.5% by weight of an antifoaming agent.

[0017] In other preferred embodiments, the composition of the present invention may contain 15 to 25% by weight of a filler, preferably 18 to 22% by weight of a filler.

[0018] Preferably, the composition of the present invention is a water-dispersible granule (WG), which can be rapidly dispersed or dissolved when added to water in a spray tank and can therefore be defined as a solid granular formulation that realizes a fine particle suspension containing an active ingredient for killing pests. Water-dispersible granules containing the composition of the present invention can be prepared by standard methods. Water-dispersible granules may take the form of extruded granules or spray-coated granules.

[0019] Preferably, in the aqueous composition according to the present invention (e.g., a tank mix preparation for application to crops), the adjuvant is selected from mineral oil, vegetable oil, esterified vegetable oil, methylated vegetable oil, or an alkyl phosphate-based adjuvant. A pesticide adjuvant can be defined as a substance present in a pesticide composition (e.g., a concentrated active ingredient formulation diluted in water in a tank for foliar application to crops), which improves the performance of the pesticide active ingredient by, for example, promoting the diffusion of the active ingredient on the leaf surface or its penetration into the leaves of the crop plant.

[0020] Examples of adjuvant classes that can be used in the present invention include adjuvants based on mineral oil, vegetable oil, esterified vegetable oil, methylated vegetable oil, or alkyl phosphate. Commercially available adjuvant products that can be mixed in a tank to produce a spray formulation having the composition of the present invention include HASTEN (trademark) (Victorian Chemical Co. Pty. Ltd. - blend of esterified vegetable oil and nonionic surfactant), OCHIMA (registered trademark) (Syngenta - alkyl ester of phosphoric acid (EC formulation)), LEDNA (trademark) (Polaquimia - EC formulation containing methyl ester of soybean oil), Atplus (registered trademark) 463 (CRODA Europe Limited - 60% paraffin oil with surfactant blend), Actirob (registered trademark) B (Bayer AG - methyl ester of rapeseed oil (esterified vegetable oil)), Destiny (registered trademark) HC (Winfield Solutions LLC - methylated soybean oil), DYNE-AMIC (registered trademark) (HELENA - blend of (methylated) vegetable oil and organosilicon-based nonionic surfactant), and FS Optique (trademark) (GROWMARK, Inc. - methyl ester of canola oil).

[0021] When an alkyl phosphate-based adjuvant is used in conjunction with the pest-killing composition according to the present invention (i.e., in a tank mix), the alkyl phosphate of the adjuvant is preferably tris-(2-ethylhexyl) phosphate combined with sorbitol ethoxylated hexaoleate, such as OCHIMA®-EC or Syngenta.

[0022] A dispersant or a dispersing agent is typically a surfactant substance that makes it more possible to separate particles when added to a suspension of solid particles in a liquid, in order to avoid their sedimentation or aggregation together. Dispersants that can be used according to the present invention include, but are not limited to, lignosulfonates (e.g., Ufoxane 3A, Borregard AS; Borresperse NA, Borregard AS; Polyfon™ H, Ingevity; Marasperse CBOS-4 powder, LignoTech), naphthalenesulfonates (e.g., Dispergator B Gran, TFL Ledertechnik GmbH), copolymers of 2,5-furandione and 2,4,4-trimethylpentene (e.g., Geropon® Ta / 72, Solvay).

[0023] An antifoaming agent is a chemical additive that reduces and prevents the formation of foam in a composition, e.g., a pesticidal composition. Antifoaming agents that can be used according to the present invention include, but are not limited to, polydimethylsiloxanes (e.g., XIAMETER™ ACP-1500, Dow, Inc; Antifoam MSA, Univar; Xiameter ACP-0001, Dow Brasil; Xiameter ACP-0100, Dow Chemical).

[0024] Fillers that can be used according to the present invention include, but are not limited to, polymethyl urea resins (Pergopak® M, Huber Engineered Materials; Cropal UF100H, Yoo Sung Chem R&T Co, Ltd), lactose monohydrate (Pharmatose® 200M, DFE Pharma; lactose monohydrate, Foremost Farms USA; Excipress™, Armor Pharma; Excipure™, Armor Pharma; lactose anhydrous, Kerry Inc).

[0025] Examples of pests that can be controlled by the compositions of the present invention include the following: From the order Acari (Acarina), for example, the genera Acalitus, Aculus, Acaricalus, Aceria, Acarus siro, Amblyomma, Argas, Boophilus, Brevipalpus, Bryobia, Calipitrimerus, Chorioptes, Dermanyssus gallinae, and Dermatophagoides. spp.) Eotetranychus spp., Eriophyes spp., Hemitarsonemus spp., Hyalomma spp., Ixodes spp., Olygonychus spp., Ornithodoros spp., Polyphagotarsone latus, Panonychus spp., Phyllocoptruta oleivora, Phytonemus spp., Polyphagotarsonemus spp., Psoroptes (spp.), genera Rhipicephalus, Rhizoglyphus, Sarcoptes, Steneotarsonemus, Tarsonemus, and Tetranychus; From the order Anoplura, for example, the genera Haematopinus, Linognathus, Pediculus, Pemphigus, and Phylloxera; From the order Coleoptera, for example, the genera Agriotes, Amphimallon majale, Anomala orientalis, Anthonomus, Aphodius, Astylus atromaculatus, Atenius, Atomaria linearis, Chaetocnema tibialis, Cerotoma, Connoderus, Cosmopolites, Cotinis nitida, and Curculio. spp.), Cyclocephala spp., Dermestes spp., Diabrotica spp., Diloboderus abderus, Epilachna spp., Eremnus spp., Heteronychus arator, Hypothenemus hampei, Lagria vilosa, Leptinotarsa ​​decemLineata, Lissorhoptrus spp., Liogenys spp., Maecolaspis spp., Maledra Castanea), Megascelis spp., Melighetes aeneus, Melolontha spp., Myochrous armatus, Orycaephilus spp., Otiorhynchus spp., Phyllophaga spp., Phlyctinus spp.), Popillia spp., Psylliodes spp., Rhyssomatus aubtilis, Rhizopertha spp., Scarabaeidae family, Sitophilus spp., Sitotroga spp., Somaticus spp., Sphenophorus spp., Sternechus subsignatus, Tenebrio spp., Tribolium spp., and Trogoderma spp.; From the order Diptera, for example, there are genera such as Aedes, Anopheles, Antherigona soccata, Bactrocea oleae, Bibio hortulanus, Bradysia, Calliphora erythrocephala, Ceratitis, Chrysomyia, Culex, Cuterebra, Dacus, Delia, Drosophila melanogaster, and Fannia. spp.), Gastrophilus spp., Geomyza tripunctata, Glossina spp., Hypoderma spp., Hyppobosca spp., Liriomyza spp., Lucilia spp., Melanagromyza spp., Musca spp., Oestrus spp., Orseolia spp., Oscinella frit, Pegomyia hyoscyami, Phorbia (spp.), Rhagoletis spp., Riveria quadrifasciata, Scatella spp., Sciara spp., Stomoxys spp., Tabanus spp., Tannia spp., and Tipula spp.; From the order Hemiptera, for example, Acanthocoris scabrator, Acrosternum spp., Adelphocoris lineolatus, Amblypelta nitida, Bathycoelia thalassina, Blissus spp., Cimex spp., Clavigralla tomentosicollis, Creontiades spp., Distantiella theobroma, Dichelops furcatus, Dysdercus spp., Edessa spp.) Euchistus spp., Eurydema pulchrum, Eurygaster spp., Halyomorpha halys, Horcias nobilellus, Leptocorisa spp., Lygus spp., Margarodes spp., Murgantia histrionic, Neomegalotomus spp., Nesidiocoris tenuis, Nezara spp., Nysius simulans, Oebalus insularis (insularis), Piesma spp., Piezodorus spp., Rhodnius spp., Sahlbergella singularis, Scaptocoris castanea, Scotinophara spp., Thyanta spp., Triatoma spp.), and Vatiga illudens; From the order Homoptera, for example, Acyrthosium pisum, Adalges spp., Agalliana ensigera, Aganoscena targionii, Aleurodicus spp., Aleurocanthus spp., Aleurolobus barodensis, Aleurothrixus floccosus, Aleyrodes brassicae, Amarasca biguttula, Amritodus atkinsoni, and Aonidiella. (spp.), Red scale insect (Aonidiella auranti), Aphididae family, Cotton aphid (Aphis spp.), Aspidiotus spp., Potato aphid (Aulacorthum solani), Bactericera cockerelli, Bemisia spp, Brachycaudus spp, Radish aphid (Brevicoryne brassicae), Cacopsylla spp, Carrot aphid (Cavariella aegopodii Scop.), Ceroplaster spp.), Chrysomphalus aonidium, Greenhouse scale insect (Chrysomphalus dictyospermi), Cicadella spp., White leafhopper (Cofana spectra), Cryptomyzus spp., Cicadulina spp., Flat scale insect (Coccus hesperidum), Dalbulus maidis, Dialeurodes spp., Citrus psyllid (Diaphorina citri), Diuraphis noxia, Dysaphis spp., Empoasca spp., Apple woolly aphid (Eriosoma larigerum), Erythroneura spp., Gascardia spp., Glycaspis brimblecombei, Hyadaphis pseudobrassicae, Hyalopterus spp., Hyperomyzus pallidus, Idioscopus clypealis, Jacobiasca lybica, Laodelphax spp., Lecanium corni, Lepidosaphes spp., Lopaphis erysimi), Lyogenys maidis, Macrosiphum spp., Mahanarva spp., Metcalfa pruinosa, Metopolophium dirhodum, Myndus crudus, Myzus spp.), Neotoxoptera sp., Nephotettix spp., Nilaparvata spp., Nippolachnus piri Mats, Odonaspis ruthae, Oregma lanigera Zehnter, Parabemisia myricae, Paratrioza cockerelli, Parlatoria spp., Pemphigus spp., Peregrinus maidis, Perkinsiella spp., Phorodon humuli), Phylloxera spp., Planococcus spp., Pseudaulacaspis spp., Pseudococcus spp., Cotton flea beetle (Pseudatomoscelis seriatus), Psylla spp., Pulvinaria aethiopica, Quadraspidiotus spp., Quesada gigas, Lightning leafhopper (Recilia dorsalis), Rhopalosiphum spp., Saissetia spp., Scaphoideus (spp.), Schizaphis spp., Sitobion spp.), Sogatella furcifera, Spissistilus festinus, Tarophagus Proserpina, Toxoptera spp., Trialeurodes spp., Tridiscus sporoboli, Trionymus spp., Trioza erytreae, Unaspis citri, Zygina flammigera, and Zyginidia scutellaris; From the order Hymenoptera, for example, the genera Acromyrmex, Arge, Atta, Cephus, Diprion, Diprionidae, Gilpinia polytoma, Hoplocampa, Lasius, Monomorium pharaonis, Neodiprion, Pogonomyrmex, Slenopsis invicta, Solenopsis, and Vespa; From the order Isoptera, for example, the genera Coptotermes, Corniternes cumulans, Incisitermes, Macrotermes, Mastotermes, Microtermes, Reticulitermes, and Solenopsis gemminate; From the order Lepidoptera, for example, the genera Acleris spp., Adoxophyes spp., Aegeria spp., Agrotis spp., Alabama argillaceae, Amylois spp., Anticarsia gemmatalis, Archips spp., Argyresthia spp., Argyrotaenia spp., Autographa spp., Bucculatrix thurberiella, Busseola fusca, Cadra cautella), peach fruit moth (Carposina nipponensis), Chilo spp., Choristoneura spp., Chrysoteuchia topiaria, grape leafroller (Clysia ambiguella), Cnaphalocrocis spp., Cnephasia spp., Cochylis spp., Coleophora spp., Colias lesbia, cotton leafroller (Cosmophila flava), Crambus spp., hairy leafroller (Crocidolomia binotalis), Cryptophlebia leucotoreta leucotreta), Cydalima perspectalis, Cydia spp., Diaphania perspectalis, Diatraea spp., Diparopsis castanea, Earias spp.), Eldana saccharina, Ephestia spp., Epinotia spp., Estigmene acrea, Etiella zinckinella, Eucosma spp., Eupoecilia ambiguella, Euproctis spp., Euxoa spp., Feltia jaculiferia, Grapholita spp., Hedya nubiferana, Heliothis spp., Hellula undalis, Herpetogramma spp.), fall webworm (Hyphantria cunea), Keiferia lycopersicella, sorghum moth (Lasmopalpus lignosellus), Leucoptera scitella, Lithocollethis spp., Lobesia botrana, Loxostege bifidalis, Lymantria spp., Lyonetia spp., Malacosoma spp., armyworm (Mamestra brassicae), tobacco hawk moth (Manduca sexta), Mythimna spp., Noctua spp., Operophtera spp., Orniodes indica, Ostrinia nubilalis, Pammene spp., Pandemis spp.), pine moth (Panolis flammea), Papaipema nebris, cotton beetle (Pectinophora gossypiela), coffee leafminer (Perileucoptera coffeella), Pseudaletia unipuncta, potato moth (Phthorimaea operculella), cabbage white butterfly (Pieris rapae), Pieris spp., diamondback moth (Plutella xylostella), Prays spp., Pseudoplusia spp., Rachiplusia nu, Richia albicosta, Scirpophaga spp., Sesamia (spp.), genera Sparganothis, Spodoptera, Sylepta derogate, Synanthedon, Thaumetopoea, Tortrix, Trichoplusia ni, Tuta absoluta, and Yponomeuta spp.; From the order Mallophaga, for example, the genera Damalinea and Trichodectes; From the order Orthoptera, for example, the genera Blatta, Blattella, Grilloalpa, Leucophaea maderae, Locusta, Neocurtilla hexadactyla, Periplaneta, Scapteriscus, and Schistocerca; From the order Psocoptera, for example, the genus Liposcelis spp.; From the order Siphonaptera, for example, the genera Ceratophyllus, Ctenocephalides, and Xenopsylla cheopis; From the order Thysanoptera, for example, Calliothrips phaseoli, Frankliniella spp., Heliothrips spp., Hercinotothrips spp., Parthenothrips spp., Scirtothrips aurantii, Sericothrips variabilis, Taeniothrips spp., Thrips spp.; and / or From the silvery-eyed species (Thysanura), for example, the European silverfish (Lepisma saccharina).

[0026] Examples of soil-dwelling pests that can damage crops in the early stages of plant development are as follows: From the order Lepidoptera, for example, there are genera such as Acleris spp., Aegeria spp., Agrotis spp., Alabama argillaceae, Amylois spp., Autographa spp., Busseola fusca, Cadra cautella, Chilo spp., Crocidolomia binotalis, Diatraea spp., Diparopsis castanea, Elasmopalpus spp., and Heliothis. (spp.), armyworm (Mamestra brassicae), potato moth (Phthorimaea operculella), diamondback moth (Plutella xylostella), genera Scirpophaga (spp.), Sesamia (spp.), Spodoptera (spp.), and Tortrix (spp.); From the order Coleoptera, for example, the genera Agriotes, Anthonomus, Atomaria linearis, Chaetocnema tibialis, Conotrachelus, Cosmopolites, Curculio, Dermestes, Diabrotica, Dilopoderus, Epilachna, Eremnus, and Heteronychus. (spp.), Lissorhoptrus spp., Melolontha spp., Orycaephilus spp., Otiorhynchus spp., Phlyctinus spp., Popillia spp., Psylliodes spp., Rhizopertha spp., Scarabaeidae, Sitotroga spp., Somaticus spp., Tanymecus spp., Tenebrio spp., Tribolium (spp.), the genera Trogoderma and Zabrus; From the order Orthoptera, for example, the genus Gryllotalpa; From the order Isoptera, for example, the genus Reticulitermes spp.; From the order Psocoptera, for example, the genus Liposcelis spp.; From the order Anoplura, for example, the genera Haematopinus, Linognathus, Pediculus, Pemphigus, and Phylloxera; From the order Homoptera, for example, the apple woolly aphid (Eriosoma larigerum); From the order Hymenoptera, for example, the genera Acromyrmex, Atta, Cephus, Lasius, Monomorium pharaonis, Neodiprion, Solenopsis, and Vespa; From the order Diptera, for example, the genus Tipula (crane fly); Flea beetles (crucifer flea beetle) (Phyllotreta spp.), root maggots (Delia spp.), cabbage seedpod weevils (Ceutorhynchus spp.), and aphids that infest plants of the Brassicaceae family.

[0027] In particular, the compositions of the present invention can be applied to insects from the order Homoptera (especially whiteflies, aphids, psyllids, scale insects, and gall insects), Thysanoptera (thrips), Acari (mites), and Lepidoptera (butterflies and moths, and their larvae). Preferably, the compositions of the present invention can be applied to whiteflies, aphids, and thrips.

[0028] Useful plant crops that can use the compositions according to the present invention include perennial and annual crops, for example, berries, such as blackberries, blueberries, cranberries, raspberries and strawberries; cereals, such as barley, corn (sorghum), millet, wild oats, rice, rye, sorghum and wheat; fiber plants, such as cotton, flax, jute and sisal; field crops, such as sugar and fodder beets, coffee, hops, mustard, rapeseed (canola), poppies, sugarcane, sunflowers, tea and tobacco; fruit trees, such as apples, apricots, avocados, bananas, cherries, citrus fruits, nectarines, peaches, pears and plums; grasses, such as buckwheat, bluegrass, bentgrass, centipedegrass, rhynchophylla, ryegrass, and Zoysia grass and Zoysia japonica; herbs, e.g., basil, borage, chives, coriander, lavender, rabrage, mint, oregano, parsley, rosemary, sage, and thyme; legumes, e.g., kidney beans, lentils, peas, and soybeans; nuts, e.g., almonds, cashews, peanuts, hazelnuts, peanuts, pecans, pistachios, and walnuts; palms, e.g., oil palm; ornamental plants, e.g., flowers, shrubs, and trees; other trees, e.g., cocoa, coconut, olive, and rubber; vegetables, e.g., asparagus, eggplant, broccoli, cabbage, carrots, cucumbers, garlic, lettuce, mallow, melon, watermelon, okra, onions, chives, pepper, potatoes, pumpkins, squash, rhubarb, spinach, and tomatoes; and climbing plants, e.g., grapes. The compositions of the present invention can also be applied to turf, lawn, and pasture.

[0029] Preferably, the composition of the present invention, - Order Solanaceae (including tomatoes, potatoes, eggplants, chili peppers, peppers, and tobacco); - Order Cucurbitaceae (including squash, pumpkin, watermelon, melon, and cucumber); - Family Alliaceae (including onions, garlic, and chives); - Order Asparagaceae (including asparagus) It can be applied to crops of useful plants selected from among them.

[0030] Preferably, the compositions of the present invention can be applied to crops of useful plants selected from cucumbers, squash, pepper, melons, watermelons, tomatoes, eggplants, zucchini, or gourds.

[0031] The application rate of the agricultural chemical composition of the present invention is determined by the required degree of control, such as the specific type of insect to be controlled, as well as the timing and method of application, and can be easily determined by those skilled in the art. Generally, the composition of the present invention can be applied at an application rate of 0.005 kilograms / hectare (kg / ha) to about 5.0 kg / ha, based on the total amount of active ingredients in the composition. An application rate of about 0.1 kg / ha to about 1.5 kg / ha is preferred, and an application rate of about 0.3 g / ha to 0.8 kg / ha is particularly preferred.

[0032] The pest-killing composition of the present invention can be used as an insecticide to control harmful organisms on cotton or soybean plants, particularly for the control of insects from the order Homoptera (especially whiteflies, aphids, psyllids, scale insects, and gall insects), Thysanoptera (thrips), and Acari (mites).

[0033] In particular, genetically modified cotton vents expressing useful traits that can be used in combination with the compositions of the present invention include BXN10211, BXN10215, BXN10222, BXN10224, COT102, COT67B, GHB614, GHB119, LLCotton25, MON531, MON757, MON15985, MON1445, MON88913, MON1076, MON1698, MON88701, T304-40, 281-24-236, 3006-210-23, 31707, 31803, 31808, 42317, and others. Such combinations of the compositions of the present invention with cotton vents expressing one or more useful traits can provide longer-lasting yield protection, enable resistance management strategies for target pest control, reduce inputs for farmers, and save significant costs in terms of time and money.

[0034] Furthermore, genetically modified soybean plants expressing toxins, such as insecticidal proteins, such as delta-endotoxins, such as Cry1Ac (Cry1Ac Bt protein), may be used in combination with the compositions of the present invention. Thus, this may include genetically modified soybean plants containing event MON87701 (see U.S. Patent No. 8,049,071 and related applications and patents, and International Publication No. 2014 / 170327A1 (see, for example, paragraph

[0008] to Intacta RR2PRO® soybeans)), event MON87751 (U.S. Patent Application Publication No. 2014 / 0373191), or event DAS-81419 (U.S. Patent No. 8,632,978 and related applications and patents).

[0035] Other genetically modified soybean plants include: Event SYHT0H2-HPPD resistance (U.S. Patent Application Publication No. 2014 / 0201860 and related applications and patents), Event MON89788-glyphosate resistance (U.S. Patent Application Publication No. 7,632,985 and related applications and patents), Event MON87708-dicamba resistance (U.S. Patent Application Publication No. 2011 / 0067134 and related applications and patents), Event DP-35 Event A2704-12-Glufosinate resistance (U.S. Patent Application Publication No. 2010 / 0184079 and related applications and patents), Event A2704-12-Glufosinate resistance (U.S. Patent Application Publication No. 2008 / 0320616 and related applications and patents), Event DP-305423-1-ALS resistance (U.S. Patent Application Publication No. 2008 / 0312082 and related applications and patents), Event A5547-127 - Glufosinate resistance (see U.S. Patent Publication No. 2008 / 0196127 and related applications and patents), resistance to Event DAS-40278-9-2,4-dichlorophenoxyacetic acid and aryloxyphenoxypropionate (see International Publication Nos. 2011 / 022469, 2011 / 022470, 2011 / 022471 and related applications and patents), Event 127-ALS resistance (International Publication No. 2010 / 080829 and related applications and patents), may include resistance to event GTS40-3-2-glyphosate, resistance to event DAS-68416-4-2,4-dichlorophenoxyacetic acid and glufosinate, resistance to event FG72-glyphosate and isoxaflutol, resistance to event BPS-CV127-9-ALS and GU262-glufosinate, or resistance to event SYHT04R-HPPD.

[0036] In an aqueous composition comprising a pest-killing composition according to the present invention (e.g., a tank mix composition), abamectin, acequinosyl, acetoprole, acrinatrin, acinonapyr, afidopyropene, afoxolaner, alanicarb, allethrin, alphacypermethrin, alphamethrin, amidoflumethrin, aminocarb, azocyclotin, bensultap, benzoximate, benzpyrimoxane, betacyfluthrin, betacypermethrin, bifenazate, bifenthrin, binapacrylic, bioalethrin, bioalethrin S-cyc Lopentyl isomer, violethmethrin, bistriflurone, broflanilide, broflutrinate, bromophosethyl, buprofezin, butocarboxime, kazusaphos, carbaryl, carbosulfan, cartap, CAS number: 1472050-04-6, CAS number: 1632218-00-8, CAS number: 1808115-49-2, CAS number: 2032403-97-5, CAS number: 2044701-44-0, CAS number: 2128706-05-6, CAS number: 2249718-27-0, chlorantraniliprole, chlordane, Chlorfenapyr, chloroprallethrin, chromafenozide, clenpyrin, chloetocarb, clothianidin, 2-chlorophenyl N-methylcarbamate (CPMC), cyanophenphos, cyantraniliprole, cyclaniliprole, cyclobutrifluram, cycloprothrin, cycloxapride, cycloxapride, cyenopyrafen, cyetopyrafen (or etopyrafen), cyflumetofen, cyfluthrin, cyhalodiamid, cyhalothrin, cypermethrin, cyphenothrin, cyprofuranilide, cyromazine, deltamethrin, diaphe Nthiuron, Dialifos, Dibrom, Dichloromezothiaz, Diflovidazine, Diflubenzuron, Zinpropyridaz, Dinactin, Dinocap, Dinotefuran, Dioxabenzophos, Emamectin, Empenthrin, Epsilon-Monfluorothrin, Epsilon-Metofluthrin, Esfenvalerate, Ethion, Ethiprole, Etofenprox, Ethoxazole, Fanfar, Phenazaquin, Fenfluthrin, Fenitrothion, Phenobucarb, Phenothiocarb, Phenoxycarb, Fenpropathrin, Fenpyroximate,Fensulfotion, fenthion, fentin acetate, fenvalerate, fipronil, flomethin, flonicamide, fluacrypyrim, fluazindolidine, fluazuron, flubendiamide, flubendimine, flucitrinate, flucycloxurone, flucitrinate, fluensulfone, fluphenelim, flufenprox, flufiprol, fluhexaphon, flumethrin, fluopyram, flupyradiflon, flupyrim, fluralaner, flpenthiofenox, fluvalinate, fluxamethamide, fosthiaze Gamma-cyhalothrin, Gossyplure (trademark), guadipyr, halofenozide, halofenozide, halofenprox, heptafluthrin, hexythiazox, hydramethylnon, imiciaphos, imidacloprid, imiprothrin, indoxacarb, iodomethane, iprodione, isocycloserum, isothioate, ivermectin, kappa-bifenthrin, kappa-tefluthrin, lambda-cyhalothrin, lepimectin, lufenuron, metaflumizone, metaldehyde, metam, methomyl, methoxyfenozide, metoflu Thrin, Metolcarb, Mexacalbate, Milbemectin, Monfluorothrin, Nicofluprole, Niclosamide, Nitenpyram, Nichiazine, Omethoate, Oxamyl, Oxazosulfyl, Parathion ethyl, Permethrin, Phenothrin, Phosphocarb, Piperonylbutoxide, Pyrimikab, Pyrimifosmethyl, Polynuclear disease virus, Prallethrin, Profenofos, Profenofos, Profluthrin, Propargit, Purpetamfos, Propoxul, Prothiofos, Protrifenbut, Piflubamide, Pymetrozine, Pyraclofos, Pi Lafluprole, pyridaben, pyridaryl, pyrifluquinazon, pyrimidifen, pyrimostropin, pyriproxyfen, resmethrin, sarolaner, selamectin, silafluofen, spinetram, spinosad, spirodiclofen, spiromesifen, spirotetramato, sulfoxaflor, tebufenozide, tebufenpyrad, tebupirimiphos, tefluthrin, temephos, tetrachloraniliprole, tetradiphon, tetramethrin, tetramethylfluthrin, tetranactin, tetraniliprole, theta-cypermethrin,Further components may be added, including an active pesticide selected from one or more of the following: thiacloprid, thiamethoxam, thiocyclam, thiodicarb, thiophanox, thiometon, thiosultap, thioxazafen, tolfenpyrad, toxafen, tralomethrin, transfluthrin, triazameate, triazophos, trichlorfon, trichloronate, trichlorfon, triflumezopyrim, ticlopyrazoflor, and zeta-cypermethrin. [Examples]

[0037] The following examples illustrate the present invention and, in particular, demonstrate the remarkable effect of using a specific amount of organic acid, citric acid, as a buffering component for the stability of spiropidione in thermal storage tests, and thus serve to demonstrate a viable composition for commercial pest control use. Compositions according to the present invention are prepared, for example, by known formulation methods for water-dispersible (soluble) granules.

[0038] Referring to Table 1 below, Composition A is a composition as a water-dispersible granule not according to the present invention (without citric acid), and Composition B is a composition as a water-dispersible granule according to the present invention (with citric acid). Compositions A and B are identical except that they contain citric acid and, in the case of Composition B, a slightly lower amount of filler present to offset the presence of the citric acid component.

[0039] To test the chemical stability of the active ingredients (spiropidione and acetamiprid), samples of composition A and composition B were slurryed in 50% by weight of water and stored at 54°C for two weeks.

[0040] Table 1: TIFF0007850151000001.tif52142

[0041] Table 2: TIFF0007850151000002.tif50159 Another aspect of the present invention may be as follows: 〔1〕 A pest-killing composition, (i) 25-35% by weight of spiropidione; (ii) 20-30% by weight of acetamiprid; and (iii) 2.5 to 10% by weight of a buffering agent (relative to the total weight of the composition) (a) 2 to 7% by weight of alkali metal sulfates and / or alkaline earth metal sulfates, (b) 0.1 to 5% by weight of organic acid (including) A pest-killing composition containing the above. 〔2〕 (i) 28-32% by weight of spiropidione; and (ii) 22-26% by weight of acetamiprid A pest-killing composition as described in [1], comprising: 〔3〕 (iii) 4.5 to 8% by weight of buffering agent (relative to the total weight of the composition) (a) 4-6% by weight of alkali metal sulfate, and (b) 0.5 to 2.5% by weight of organic acid (including) A pest-killing composition according to [1] or [2], comprising: 〔4〕 The pest-killing composition according to any one of [1] to [3], wherein the alkali metal sulfate is potassium sulfate or sodium sulfate, preferably sodium sulfate. 〔5〕 The pest-killing composition according to any one of [1] to [4], wherein the organic acid is citric acid or a salt thereof. 〔6〕 (iv) 15-20% by weight of one or more dispersants; (v) 1-5% by weight of an antifoaming agent; and (vi) 15-30% by weight of filler (optionally, the filler is in proportion to the total weight of the composition) (c) 5-15% by weight of polymethylurea resin filler, and (d) 10-15% by weight lactose monohydrate filler (including) A pest-killing composition according to any one of [1] to [5], further comprising: 〔7〕 The composition according to any one of [1] to [6], further comprising one or more additional components selected from humectants, biocides, stabilizers, and pigments. 〔8〕 A pest-killing composition according to any one of the items [1] to [7], which is a water-dispersible granule. 〔9〕 An aqueous composition comprising a pest-killing composition described in any one of items (1) to (8), and optionally further comprising one or more adjuvants or carriers. 〔10〕 The aqueous composition according to [9], wherein the adjuvant is selected from mineral oil, vegetable oil, esterified vegetable oil, methylated vegetable oil, or an adjuvant based on an alkyl phosphate, preferably an adjuvant based on an alkyl phosphate. 〔11〕 A method for combating and controlling harmful organisms, comprising applying a composition described in any one of items [1] to

[10] to a harmful organism, to the habitat of a harmful organism, or to a useful plant crop that is susceptible to attacks by a harmful organism. 〔12〕 The method according to

[11] , wherein the harmful organism is selected from the order Homoptera, Thysanoptera, Acarina, or Lepidoptera. 〔13〕 The method according to

[12] , wherein the pest is selected from whiteflies, aphids, and thrips. 〔14〕 (i) The plants are soybeans and cotton; or (ii) Fruits and vegetables, in particular selected from the genus Cucurbita or the family Solanaceae, The method described in any one of items

[10] to

[13] . 〔15〕 The method according to any one of

[10] to

[13] , wherein the plant is selected from cucumber, melon, watermelon, citrus fruit, onion, grape, tomato, pepper, chili pepper, potato, and okra.

[0042] Table 2: TIFF0007850151000003.tif41132

Claims

1. A pest-killing composition, (i) 25-35% by weight of spiropidione; (ii) 20-30% by weight of acetamiprid; and (iii) 2.5 to 10% by weight of buffering agent (relative to the total weight of the composition, (a) 2 to 7% by weight of alkali metal sulfates and / or alkaline earth metal sulfates, (b) 0.1 to 5% by weight of organic acid (including) A pest-killing composition containing the above.

2. (i) 28-32% by weight of spiropidione; and (ii) 22-26% by weight of acetamiprid The pest-killing composition according to claim 1, comprising:

3. (iii) 4.5 to 8% by weight of buffering agent (relative to the total weight of the composition, (a) 4 to 6% by weight of alkali metal sulfates, (b) 0.5 to 2.5% by weight of organic acid (including) A pest-killing composition according to claim 1 or claim 2, comprising:

4. The pest-killing composition according to any one of claims 1 to 3, wherein the alkali metal sulfate is potassium sulfate or sodium sulfate.

5. The pest-killing composition according to claim 4, wherein the alkali metal sulfate is sodium sulfate.

6. The pest-killing composition according to any one of claims 1 to 5, wherein the organic acid is citric acid or a salt thereof.

7. (iv) 15-20% by weight of one or more dispersants; (v) 1 to 5% by weight of an antifoaming agent; and (vi) 15 to 30% by weight of a filler (the filler is in proportion to the total weight of the composition) (c) 5 to 15% by weight of polymethylurea resin filler, and (d) 10-15% by weight of lactose monohydrate filler (including) A pest-killing composition according to any one of claims 1 to 6, further comprising:

8. The composition according to any one of claims 1 to 7, further comprising one or more components selected from humectants, biocides, stabilizers, and pigments.

9. A pest-killing composition according to any one of claims 1 to 8, which is a water-dispersible granule.

10. An aqueous composition comprising the pest-killing composition according to any one of claims 1 to 9, further comprising one or more adjuvants or carriers.

11. The aqueous composition according to claim 10, wherein the adjuvant is selected from mineral oil, vegetable oil, esterified vegetable oil, methylated vegetable oil, or an adjuvant based on alkyl phosphate.

12. The aqueous composition according to claim 11, wherein the adjuvant is an adjuvant based on an alkyl phosphate.

13. A method for combating and controlling harmful organisms, comprising applying the composition described in any one of claims 1 to 12 to the harmful organism, to the habitat of the harmful organism, or to a useful plant crop that is susceptible to attacks by the harmful organism.

14. The method according to claim 13, wherein the harmful organism is selected from the order Homoptera, Thysanoptera, Acari, or Lepidoptera.

15. The method according to claim 14, wherein the aforementioned pest is selected from whiteflies, aphids, and thrips.

16. The plant is (i) Soybeans and cotton; or (ii) Fruits and vegetables The method according to any one of claims 13 to 15, selected from the following.

17. The method according to any one of claims 13 to 16, wherein the plant belongs to the genus Cucurbita or the family Solanaceae.

18. The method according to any one of claims 13 to 16, wherein the plant is selected from cucumber, melon, watermelon, citrus fruit, onion, grape, tomato, pepper, chili pepper, potato, and okra.

Images