Optimization of preservative concentration in personal care compositions

Abstract

The present invention relates to hair care compositions comprising from about 8 to about 17% of one or more surfactants and from about 0.04 to about 0.18% of a salicylate or acid.

Description

[Technical Field]

[0001] The present invention relates to a hair care composition containing a preservative that exhibits effective microbial protection in a personal care composition at a lower preservative concentration. [Background technology]

[0002] Preservatives are substances added to personal care compositions such as shampoos, body washes, body lotions, ointments, creams, and other similar products, primarily to inhibit the growth of microorganisms that may result from contamination by consumers during use. Inhibiting the growth of bacteria and fungi is paramount to maintaining product quality, extending shelf life, and protecting consumers. There is a growing consumer demand for reduced amounts of preservatives used in consumer products. However, exposure to insufficient concentrations of preservatives or antimicrobial agents can lead to the selection and emergence of resistant strains. Therefore, there is a need to use preservatives that are sufficiently high in concentration to suppress microbial growth and maintain product quality, but sufficiently low in concentration to address consumer concerns. [Overview of the project] [Problems that the invention aims to solve]

[0003] Remarkably, it was found that unprecedentedly low concentrations of sodium benzoate and sodium salicylate could provide effective microbial preservation for personal care compositions while simultaneously meeting consumer demand for even lower concentrations of preservatives. [Means for solving the problem]

[0004] The present invention relates to a personal care composition comprising about 8 to about 17% of one or more surfactants and about 0.04 to about 0.18% of salicylates or acids.

[0005] These and other features, aspects, and advantages of the present invention will become apparent to those skilled in the art by reading this disclosure. [Modes for carrying out the invention]

[0006] Unless otherwise specified, all percentages and ratios used herein are based on the weight of the whole composition. Unless otherwise specified, all measurements are understood to be performed under ambient conditions, where “ambient conditions” means conditions of approximately 25°C, approximately 1 atmosphere, and approximately 50% relative humidity. All numerical ranges include narrower ranges. The upper and lower range limits described are combinable to create further ranges not explicitly described.

[0007] The compositions of the present invention include, essentially consist of, or comprise the essential and optional components described herein. As used herein, “essentially consisting of” means that a composition or component may include additional components, but only if the additional components do not substantially alter the basic and novel properties of the claimed composition or method.

[0008] As used in relation to the composition, "apply" or "apply" means applying or spreading the composition of the present invention onto keratinous tissue such as hair.

[0009] "Dermatologically acceptable" means that the composition or component described is suitable for use in contact with human skin tissue without excessive toxicity, incompatibility, instability, allergic reactions, etc.

[0010] "A safe and effective amount" means an amount of compound or composition sufficient to significantly induce a beneficial effect.

[0011] In the context of this invention, the term "preservation / preservation" refers to preventing or delaying the deterioration of a product by microorganisms present in the product or composition. In the context of this invention, "preservative" or "antiseptic" refers to a substance that prevents or delays the growth of microorganisms in a product or composition.

[0012] This specification concludes with the "claims" that particularly point out and clearly claim the present invention, which is considered to be better understood from the following description.

[0013] As used herein, the term "fluid" includes liquids and gels.

[0014] As used herein, articles such as "a" and "an" are understood to mean one or more of the claims or things recited when used in the claims.

[0015] As used herein, "comprising" means that other steps and other components that do not affect the final result can be added. This term encompasses the terms "consisting of" and "consisting essentially of".

[0016] As used herein, "mixture" means a simple combination of materials and any compound that can be obtained from such a combination.

[0017] As used herein, "molecular weight" or "Molecular weight" refers to the weight-average molecular weight unless otherwise specified. The molecular weight is measured using gel permeation chromatography (GPC), an industry standard method.

[0018] When ranges of amounts are recited, these are to be understood as the total amount of the component in the composition, or, where multiple species fall within the scope of the component definition, the total amount of all components in the composition that conform to that definition.

[0019] For example, if a composition contains 1% to 5% aliphatic alcohols, a composition containing 2% stearyl alcohol and 1% cetyl alcohol, and no other aliphatic alcohols, would fall within this range.

[0020] The amount of each of the specific ingredients listed below, or any mixture thereof, may constitute up to 100% (or 100%) of the total amount of one or more ingredients in the hair care composition.

[0021] When used herein, "personal care composition" includes products such as shampoos, shower gels, liquid hand washes, hair dyes, facial cleansers, and other surfactant-based liquid compositions.

[0022] As used herein, the terms "include," "includes," and "including" are understood to mean "comprise," "comprises," and "comprising," respectively, in an unrestricted sense.

[0023] All percentages, parts, and ratios are based on the total weight of the compositions of the present invention unless otherwise specified. All such weights, in the case of enumerated components, are based on the concentration of the active ingredient and therefore do not include carriers or by-products that may be present in commercially available materials.

[0024] Unless otherwise noted, all concentrations of components or compositions refer to the active portion of the component or composition, excluding impurities that may be present in the commercially available source of such components or compositions, such as residual solvents or by-products.

[0025] All maximum numerical limits given throughout this specification should be understood to include all numerical limits smaller than that, as if such smaller numerical limits were explicitly stated herein. All minimum numerical limits given throughout this specification include all numerical limits higher than that, as if such higher numerical limits were explicitly stated herein. All numerical ranges given throughout this specification include all narrower numerical ranges contained within such wider numerical ranges, as if all such narrower numerical ranges were explicitly stated herein.

[0026] Preservatives Furthermore, the composition contains one or more preservatives. Each single preservative may be present in amounts of approximately 0.04–0.18% by weight, approximately 0.04–0.15% by weight, approximately 0.07–0.18% by weight, or approximately 0.07–0.15% by weight of the composition. The preservatives may have low logS water solubility (less than 0) or high logS water solubility (greater than 0). The preservatives may have low logS water solubility (less than 0 to approximately -5.0). The preservatives may have high logS water solubility (0 to approximately 1.0). In addition, combinations of preservatives with high and low logS water solubility can also be used.

[0027] Non-limiting examples of preservatives may be salicylates or acids, benzoates or acids. Non-limiting examples of preservatives may be sodium salicylate, sodium benzoate, potassium salicylate, potassium benzoate, salicylic acid, benzoic acid, MEA salicylate, MEA benzoate, TEA salicylate, TEA benzoate, calcium salicylate, calcium benzoate, magnesium salicylate, magnesium benzoate, titanium salicylate, titanium benzoate, silver salicylate, silver benzoate, ammonium salicylate, ammonium benzoate, zinc salicylate, zinc benzoate, and combinations thereof.

[0028] The composition may consist of salicylate or acid and benzoate or acid in weight ratios of 1:1 to 5:1, 1:0.9 to 5:1, 1:0.8 to 5:1, 1:0.75 to 5:1, 1:0.9 to 4:1, 1:0.9 to 3:1, 1:0.8 to 3:1, 1:0.75 to 3:1, and 1:0.8 to 2:1.

[0029] Some preferred examples of low-logS water-soluble preservatives include metal pyrithiones, organic acids (including but not limited to undecylenic acid, salicylic acid, dehydroacetic acid, and sorbic acid), glycols (including but not limited to caprylyl glycol and decline glycol), parabens, methylchloroisothiazolinone, benzyl alcohol, ethylenediaminetetraacetic acid, and combinations thereof. Examples of commercially available low-logS water-soluble preservatives are offered under the trade names Geogard 111A®, Geoagard 221A®, Mikrokill COS®, Mikrokill ECT®, and Glycacil®. Preferred examples of high-logS water-soluble preservatives include sodium benzoate, methylisothiazolinone, DMDM ​​hydantoin, and combinations thereof.

[0030] Cleaning surfactants A hair care composition may contain more than about 8% by weight of a surfactant system that provides cleansing properties to the composition, or more than 10% by weight of a surfactant system that provides cleansing properties to the composition. The surfactant system may contain one or more surfactants. One or more surfactants may be sulfate surfactants and / or may be substantially sulfate surfactant-free. Surfactants may be selected from anionic surfactants, amphoteric surfactants, zwitterionic surfactants, nonionic surfactants, and combinations thereof. Various examples and descriptions of cleansing surfactants are described in U.S. Patent No. 8,440,605, U.S. Patent Application Publication No. 2009 / 155383, and U.S. Patent Application Publication No. 2009 / 0221463, which are incorporated herein by reference in their entirety. As used herein, "substantially sulfate-free" means containing sulfate in amounts ranging from about 0% to about 3% by weight, or about 0% to about 2% by weight, or about 0% to about 1% by weight, or about 0% to about 0.5% by weight, or about 0% to about 0.25% by weight, or about 0% to about 0.1% by weight, or about 0% to about 0.05% by weight, or about 0% to about 0.01% by weight, or about 0% to about 0.001% by weight, and / or alternatively, not containing sulfate. As used herein, "not containing" means 0% by weight.

[0031] The hair care composition may contain one or more surfactants in amounts of approximately 8% to 17% by weight, approximately 8% to 16% by weight, approximately 8% to 15% by weight, approximately 8% to 14% by weight, approximately 8% to 13% by weight, or approximately 8% to 12% by weight.

[0032] Suitable anionic surfactants for use in this composition are alkyl and alkyl ether sulfates. Other suitable anionic surfactants are water-soluble salts of organic sulfuric acid reaction products. Still other suitable anionic surfactants are reaction products of fatty acids esterified with isethionic acid and neutralized with sodium hydroxide. Other similar anionic surfactants are described in U.S. Patents 2,486,921, 2,486,922, and 2,396,278, which are incorporated herein by reference in their entirety.

[0033] Examples of anionic surfactants used in hair care compositions include ammonium lauryl sulfate, ammonium laureth sulfate, C10-15 pareth sulfate, C10-15 alkyl sulfate, C11-15 alkyl sulfate, ammonium decyl sulfate, ammonium deceth sulfate, ammonium undecyl sulfate, ammonium undeceth sulfate, triethylamine lauryl sulfate, triethylamine laureth sulfate, triethanolamine lauryl sulfate, triethanolamine laureth sulfate, monoethanolamine lauryl sulfate, monoethanolamine laureth sulfate, diethanolamine lauryl sulfate, diethanolamine laureth sulfate, sodium monoglyceride sulfate of laurate, sodium lauryl sulfate, sodium laureth sulfate, and sodium C10-15 pareth sulfate. Examples include sodium C10-15 alkyl sulfates, sodium C11-15 alkyl sulfates, sodium decyl sulfate, sodium deceth sulfate, sodium undecyl sulfate, sodium undeceth sulfate, potassium lauryl sulfate, potassium laureth sulfate, potassium C10-15 pareth sulfate, potassium C10-15 alkyl sulfates, potassium C11-15 alkyl sulfates, potassium decyl sulfate, potassium deceth sulfate, potassium undecyl sulfate, potassium undeceth sulfate, ammonium cocoyl sulfate, ammonium lauroyl sulfate, sodium cocoyl sulfate, sodium lauroyl sulfate, potassium cocoyl sulfate, potassium lauryl sulfate, triethanolamine lauryl sulfate, triethanolamine lauryl sulfate, monoethanolamine cocoyl sulfate, monoethanolamine lauryl sulfate, and combinations thereof. Anionic surfactants may be sodium lauryl sulfate or sodium laureth sulfate.

[0034] The composition of the present invention also a) R1O(CH2CHR3O) y SO3M, b) CH3(CH2) z CHR2CH2O(CH2CHR3O) y SO3M, and c) These mixtures (In the formula, R1 is CH3(CH2) 10The following may be included: R2 represents H, or a hydrocarbon group containing 1 to 4 carbon atoms such that the sum of carbon atoms in z and R2 is 8, R3 is H or CH3, y is 0 to 7, and when y is not zero (0), the average value of y is approximately 1, and M is a monovalent or divalent positively charged cation.

[0035] Suitable anionic alkyl sulfate and alkyl ether sulfate surfactants include, but are not limited to, those having branched alkyl chains synthesized from C8-C18 branched alcohols that can be selected from the group consisting of Garbet alcohols, aldol condensation-derived alcohols, oxo alcohols, FT oxo alcohols, and mixtures thereof. Non-limiting examples of 2-alkyl branched alcohols include 2-methyl-1-undecanol, 2-ethyl-1-decanol, 2-propyl-1-nonanol, 2-butyl-1-octanol, 2-methyl-1-dodecanol, 2-ethyl-1-undecanol, 2-propyl-1-decanol, 2-butyl-1-nonanol, 2-pentyl-1-octanol, 2-pentyl-1-heptanol, and trade names LIAL® (Sasol), ISALCHEM Examples include oxo alcohols such as those sold under the registered trademark (Sasol) and NEODOL (Shell), as well as garvet and aldol condensation derivative alcohols such as 2-ethyl-1-hexanol, 2-propyl-1-butanol, 2-butyl-1-octanol, 2-butyl-1-decanol, 2-pentyl-1-nonanol, 2-hexyl-1-octanol, 2-hexyl-1-decanol, and those sold under the trade name ISOFOL (Sasol), or sold as alcohol ethoxylates and alkoxylates under the trade names LUTENSOL XP (BASF) and LUTENSOL XL (BASF).

[0036] Anionic alkyl sulfates and alkyl ether sulfates may also include those synthesized from C8-C18 branched alcohols derived from butylene or propylene, sold under the trademark names EXXAL (Exxon) and Marlipal (Sasol). These include anionic surfactants of the subclass of trideceth-n sodium sulfate (STnS), where n is about 0.5 to about 3.5. Exemplary surfactants of this subclass are trideceth-2 sodium sulfate and trideceth-3 sodium sulfate. Compositions of the present invention may also include tridecyl sodium sulfate.

[0037] Examples of surfactants that are substantially sulfate-free and suitable for use in compositions include sodium, ammonium, or potassium salts of isethionate; sodium, ammonium, or potassium salts of sulfonate; sodium, ammonium, or potassium salts of ethersulfonate; sodium, ammonium, or potassium salts of sulfosuccinate; sodium, ammonium, or potassium salts of sulfoacetate; sodium, ammonium, or potassium salts of sulfolaurate; sodium, ammonium, or potassium salts of glycinate; sodium, ammonium, or potassium salts of sarcosinate; sodium, ammonium, or potassium salts of glutamate; sodium, ammonium, or potassium salts of alaninate; sodium, ammonium, or potassium salts of carboxylate; sodium, ammonium, or potassium salts of taurate; sodium, ammonium, or potassium salts of phosphate ester; and combinations thereof.

[0038] The surfactant system may include one or more amino acid-based anionic surfactants. Non-limiting examples of amino acid-based anionic surfactants include sodium, ammonium, or potassium salts of acylglycinates; sodium, ammonium, or potassium salts of acylsarcosinates; sodium, ammonium, or potassium salts of acylglutamates; sodium, ammonium, or potassium salts of acylalaninates, and combinations thereof.

[0039] Amino acid-based anionic surfactants can be glutamates, such as acyl glutamates. Non-limiting examples of acyl glutamates include sodium cocoyl glutamate, disodium cocoyl glutamate, ammonium cocoyl glutamate, diammonium cocoyl glutamate, sodium lauroyl glutamate, disodium lauroyl glutamate, sodium cocoyl hydrolyzed wheat protein glutamate, disodium cocoyl hydrolyzed wheat protein glutamate, potassium cocoyl glutamate, dipotassium cocoyl glutamate, potassium lauroyl glutamate, and Dipotassium uroyl glutamate, potassium cocoyl hydrolyzed wheat protein glutamate, dipotassium cocoyl hydrolyzed wheat protein glutamate, sodium caproyl glutamate, disodium caproyl glutamate, sodium capryloyl glutamate, disodium capryloyl glutamate, potassium capryloyl glutamate, dipotassium capryloyl glutamate, sodium undecylenoyl glutamate, disodium undecylenoyl glutamate, undecyl Potassium glutamate, dipotassium undecylenoyl glutamate, hydrogenated disodium tallow glutamate, sodium stearoyl glutamate, disodium stearoyl glutamate, potassium stearoyl glutamate, dipotassium stearoyl glutamate, sodium myristoyl glutamate, disodium myristoyl glutamate, potassium myristoyl glutamate, dipotassium myristoyl glutamate, cocoyl / hydrogenated disodium tallow glutamate, cocoyl / The group may be selected from palmoyl / sunflower oil sodium glutamate, hydrogenated tallow oil sodium glutamate, olivoyl sodium glutamate, olivoyl disodium glutamate, palmoyl sodium glutamate, palmoyl disodium glutamate, cocoyl glutamate TEA, hydrogenated tallow oil glutamate TEA, lauroyl glutamate TEA, and mixtures thereof.

[0040] Amino acid-based anionic surfactants can be alaninates, such as acyl alaninates. Non-limiting examples of acyl alaninates include sodium cocoyl alaninate, sodium lauroyl alaninate, sodium caproyl alaninate, sodium N-dodecanoyl-l-alaninate, and combinations thereof.

[0041] Amino acid-based anionic surfactants can be sarcosinates, such as acyl sarcosinates. Non-limiting examples of sarcosinates may be selected from the group consisting of sodium lauroyl sarcosinate, sodium cocoyl sarcosinate, sodium myristoyl sarcosinate, sodium caproyl sarcosinate, TEA cocoyl sarcosinate, ammonium cocoyl sarcosinate, ammonium lauroyl sarcosinate, dimer dilinoleyl bis-lauroyl glutamate / lauroyl sarcosinate, disodium lauroamphodiacetate, lauroyl sarcosinate, isopropyl lauroyl sarcosinate, potassium cocoyl sarcosinate, potassium lauroyl sarcosinate, sodium cocoyl sarcosinate, sodium lauroyl sarcosinate, sodium myristoyl sarcosinate, sodium oleoyl sarcosinate, sodium palmitoyl sarcosinate, TEA cocoyl sarcosinate, TEA lauroyl sarcosinate, TEA oleoyl sarcosinate, TEA palm kernel sarcosinate, and combinations thereof.

[0042] Amino acid-based anionic surfactants can be glycinates, such as acylglycinates. Non-limiting examples of acylglycinates include sodium cocoyl glycinate, sodium lauroyl glycinate, and combinations thereof.

[0043] The composition may contain an anionic surfactant selected from the group consisting of sulfosuccinates, isethionates, sulfonates, sulfoacetates, sulfolaurates, glucose carboxylates, alkyl ether carboxylates, acyl taurates, lactates, lactylates, and mixtures thereof.

[0044] The compositions of the present invention may further include anionic alkyl and alkyl ether sulfosuccinates, and / or dialkyl and dialkyl ether sulfosuccinates and mixtures thereof. The dialkyl and dialkyl ether sulfosuccinates may be C6-15 linear or branched dialkyl or dialkyl ether sulfosuccinates. The alkyl moieties may be symmetric (i.e., the same alkyl moiety) or asymmetric (i.e., different alkyl moieties). Non-limiting examples include disodium lauryl sulfosuccinate, disodium laureth sulfosuccinate, sodium bistridecyl sulfosuccinate, sodium dioctyl sulfosuccinate, sodium dihexyl sulfosuccinate, sodium dicyclohexyl sulfosuccinate, sodium diamyl sulfosuccinate, sodium diisobutyl sulfosuccinate, linear bis(tridecyl) sulfosuccinates and mixtures thereof.

[0045] Non-limiting examples of sulfosuccinate surfactants include disodium N-octadecyl sulfosuccinate, disodium lauryl sulfosuccinate, diammonium lauryl sulfosuccinate, sodium lauryl sulfosuccinate, disodium laureth sulfosuccinate, tetrasodium N-(1,2-dicarboxyethyl)-N-octadecyl sulfosuccinate, diamyl esters of sodium sulfosuccinate, dihexyl esters of sodium sulfosuccinate, dioctyl esters of sodium sulfosuccinate, and combinations thereof.

[0046] Suitable isethionate surfactants include reaction products of fatty acids esterified with isethionic acid and neutralized with sodium hydroxide. Suitable fatty acids for isethionate surfactants can be derived from coconut oil or palm kernel oil, such as methyl taurid amides. Non-limiting examples of isethionates can be selected from the group consisting of sodium lauroyl methyl isethionate, sodium cocoyl isethionate, ammonium cocoyl isethionate, hydrogenated sodium cocoyl methyl isethionate, sodium lauroyl isethionate, sodium cocoyl methyl isethionate, sodium myristoyl isethionate, sodium oleyl isethionate, sodium oleyl methyl isethionate, palm kernel oil (palm kerneloyl) isethionate, sodium stearoyl methyl isethionate, and mixtures thereof.

[0047] Non-limiting examples of sulfonates include α-olefin sulfonates, linear alkylbenzene sulfonates, alkylglyceryl sulfonates, sodium lauryl glucoside hydroxypropyl sulfonate, and combinations thereof.

[0048] Non-limiting examples of sulfoacetates include sodium lauryl sulfoacetate, ammonium lauryl sulfoacetate, and combinations thereof.

[0049] Non-limiting examples of sulfolaurates include sodium methyl-2-sulfolaurate, disodium sulfolaurate, and combinations thereof.

[0050] Non-limiting examples of glucose carboxylates include sodium lauryl glucoside carboxylate, sodium cocoyl glucoside carboxylate, and combinations thereof.

[0051] Non-limiting examples of alkyl ether carboxylates include sodium laureth-4 carboxylate, laureth-5 carboxylate, laureth-13 carboxylate, sodium C12-13 pareth-8 carboxylate, sodium C12-15 pareth-8 carboxylate, and combinations thereof.

[0052] Non-limiting examples of acyl taurates include sodium methyl cocoyl taurate, sodium methyl lauroyl taurate, sodium caproyl methyl taurate, sodium methyl oleoyl taurate, sodium cocoyl taurate, sodium lauroyl taurate, sodium caproyl taurate, and combinations thereof.

[0053] A non-limiting example of lactate is sodium lactate.

[0054] Non-limiting examples of lactylates include sodium lauroyl lactate, sodium cocoyl lactate, and combinations thereof.

[0055] Hair care compositions may contain co-surfactants. Co-surfactants may be selected from the group consisting of amphoteric surfactants, zwitterionic surfactants, nonionic surfactants, and mixtures thereof. Co-surfactants may be selected from the group consisting of betaine, propionate, sultaine, hydroxysultaine, amphohydroxypropyl sulfonate, alkyl amphoacetate, alkyl amphodiaacetate, and combinations thereof. Examples of co-surfactants include, but are not limited to, lauramidopropyl betaine, cocamidopropyl betaine, cocobetaine, cetyl betaine, lauryl hydroxysultaine, sodium lauroamphoacetate, disodium cocoamphodiacetate, cocamide monoethanolamide, and mixtures thereof.

[0056] The hair care composition may further contain one or more amphoteric, zwitterionic, or nonionic cosurfactants, or mixtures thereof, in amounts of approximately 0.25% to approximately 15% by weight, approximately 0.5% to approximately 15% by weight, approximately 1% to approximately 14% by weight, or approximately 2% to approximately 13% by weight.

[0057] Suitable amphoteric or zwitterionic surfactants for use in the hair care compositions of this specification include those known for use in shampoos or other hair care cleansers. Non-limiting examples of suitable zwitterionic or amphoteric surfactants are described in U.S. Patents 5,104,646 and 5,106,609, which are incorporated herein by reference in their entirety.

[0058] Suitable amphoteric cosurfactants for use in compositions include surfactants described as derivatives of aliphatic secondary and tertiary amines, in which one of the aliphatic substituents may be linear or branched, and one of the aliphatic substituents contains about 8 to about 18 carbon atoms, and the other contains an anionic group such as a carboxyl, sulfonate, sulfate, phosphate, or phosphonate. Suitable amphoteric surfactants include sodium cocaminopropionate, sodium cocaminodipropionate, sodium cocoamphoacetate, sodium cocoamphohydroxypropyl sulfonate, sodium cocoamphopropionate, sodium corn amphopropionate, sodium lauraminopropionate, sodium lauroamphoacetate, sodium lauroamphohydroxypropyl sulfonate, sodium lauroamphopropionate, sodium corn amphopropionate, sodium lauriminodipropionate, ammonium cocaminopropionate, ammonium cocaminodipropionate, ammonium cocoamphoacetate, ammonium cocoamphodiacetate, ammonium cocoamphohydroxypropyl sulfonate, ammonium cocoamphopropionate, ammonium corn amphopropionate, ammonium lauraminopropionate, ammonium lauroamphoacetate, ammonium lauroamphodiacetate, and ammonium lauroamphohydro Ammonium xypropylsulfonate, ammonium lauroamphopropionate, ammonium corn amphopropionate, ammonium lauriminodipropionate, triethanolamine cocaminopropionate, triethanolamine cocaminodipropionate, triethanolamine cocoamphoacetate, triethanolamine cocoamphohydroxypropylsulfonate, triethanolamine cocoamphopropionate, triethanolamine corn amphopropionate, triethanolamine lauraminopropionate, triethanolamine lauroamphoacetate, triethanolamine lauroamphohydroxypropylsulfonate, triethanolamine lauroamphopropionate, triethanolamine corn amphopropionate, triethanolamine lauriminodipropionate, cocoamphodipropionic acid, disodium caproamphodiacetate, disodium caproamphodipropionate, disodium capryloamphodiacetate,Examples include, but are not limited to, disodium capryloamphodipropionate, disodium cocoamphocarboxyethyl hydroxypropyl sulfonate, disodium cocoamphodiacetate, disodium cocoamphodipropionate, disodium dicarboxyethyl cocopropyldiamine, disodium laureth-5 carboxyamphodiacetate, disodium lauriminodipropionate, disodium lauroamphodiacetate, disodium lauroamphodipropionate, disodium oleoamphodipropionate, disodium PPG-2-isodecetyl-7 carboxyamphodiacetate, lauraminopropionic acid, lauroamphodipropionic acid, laurylaminopropylglycine, lauryldiethylenediaminoglycine, and mixtures thereof.

[0059] This composition may contain a zwitterionic copolymer, which is a derivative of an aliphatic quaternary ammonium, phosphonium, and sulfonium compound, where the aliphatic group may be linear or branched, one of the aliphatic substituents contains about 8 to about 18 carbon atoms, and the other contains an anionic group such as a carboxy, sulfonate, sulfate, phosphate, or phosphonate. The zwitterionic surfactant may be selected from the group consisting of cocamidoethyl betaine, cocamidopropylamine oxide, cocamidopropyl betaine, cocamidopropyl dimethylaminohydroxypropyl hydrolyzed collagen, cocamidopropyl dimonium hydroxypropyl hydrolyzed collagen, cocamidopropyl hydroxysultaine, cocobetaine amphopropionate, coco-betaine, coco-hydroxysultaine, coco / oleamidopropyl betaine, coco-sultaine, lauramidopropyl betaine, lauryl betaine, lauryl hydroxysultaine, lauryl sultaine, cetyl betaine, and mixtures thereof.

[0060] Non-limiting examples of betaine surfactants include cocodimethylcarboxymethyl betaine, oleyl betaine, lauryldimethylcarboxymethyl betaine, lauryldimethylalphacarboxyethyl betaine, cetyldimethylcarboxymethyl betaine, laurylbis-(2-hydroxyethyl)carboxymethyl betaine, stearylbis-(2-hydroxypropyl)carboxymethyl betaine, oleyldimethylgamma-carboxypropyl betaine, laurylbis-(2-hydroxypropyl)alpha-carboxyethyl betaine, and mixtures thereof. Examples of sulfobetaines include cocodimethylsulfopropyl betaine, stearyldimethylsulfopropyl betaine, lauryldimethylsulfoethyl betaine, laurylbis-(2-hydroxyethyl)sulfopropyl betaine, and mixtures thereof.

[0061] Suitable nonionic surfactants for use in the present invention include those described in McCutcheion's Detergents and Emulsifiers, North American edition (1986), Allured Publishing Corp., and McCutcheion's Functional Materials, North American edition (1992). Suitable nonionic surfactants for use in the personal care compositions of the present invention include, but are not limited to, polyoxyethylene-modified alkylphenols, polyoxyethylene-modified alcohols, polyoxyethylene-modified polyoxypropylene glycols, glyceryl esters of alkanates, polyglyceryl esters of alkanates, propylene glycol esters of alkanates, sorbitol esters of alkanates, polyoxyethylene-modified sorbitol esters of alkanates, polyoxyethylene glycol esters of alkanates, polyoxyethylene-modified alkanates, alkanolamides, N-alkylpyrrolidones, alkyl glycosides, alkyl polyglucosides, alkylamine oxides, and polyoxyethylene-modified silicones.

[0062] The co-surfactant may be one or more nonionic surfactants selected from the group consisting of alkyl polyglucosides, alkyl glycosides, acyl glucamides, alkanolamides, alkoxylated amides, glyceryl esters, and mixtures thereof.

[0063] Non-limiting examples of acylglucamides include lauroyl / myristoyl methylglucamide, capryloyl / caproyl methylglucamide, cocoyl methylglucamide, and combinations thereof.

[0064] Non-limiting examples of alkanolamides include cocamide, cocamide methyl MEA, cocamide DEA, cocamide MEA, cocamide MIPA, lauramide DEA, lauramide MEA, lauramide MIPA, myristamide DEA, myristamide MEA, PEG-20 cocamide MEA, PEG-2 cocamide, PEG-3 cocamide, PEG-4 cocamide, PEG-5 cocamide, PEG-6 cocamide, PEG-7 cocamide, PEG-3 lauramide, PEG-5 lauramide, PEG-3 oleamide, PPG-2 cocamide, PPG-2 hydroxyethyl cocamide, PPG-2 hydroxyethyl isostearamide, and mixtures thereof.

[0065] Non-limiting examples of alkoxylated amides include PPG-2 cocamide, PPG-2 hydroxyethyl cocamide, PPG-2 hydroxyethyl isostearamide, and combinations thereof.

[0066] Typical polyoxyethylene alcohols include alkyl chains in the C9-C16 range with approximately 1 to 110 alkoxy groups, such as laureth-3, laureth-23, ceteth-10, steareth-10, steareth-100, beheneth-10, and those commercially available from Shell Chemicals (Houston, Texas) under the trademark names Neodol® 91, Neodol® 23, Neodol® 25, Neodol® 45, Neodol® 135, Neodol® 67, Neodol® PC100, Neodol® PC200, and Neodol® PC600, as well as mixtures thereof, but are not limited to these.

[0067] Similarly, commercially available products include polyoxyethylene aliphatic ethers sold under the trademark name Brij® by Uniqema (Wilmington, Delaware), including, but not limited to, Brij® 30, Brij® 35, Brij® 52, Brij® 56, Brij® 58, Brij® 72, Brij® 76, Brij® 78, Brij® 93, Brij® 97, Brij® 98, Brij® 721, and mixtures thereof.

[0068] Suitable alkyl glycosides and alkyl polyglucosides can be represented by the formula (S)nOR, where S is a sugar moiety such as glucose, fructose, mannose, or galactose, n is an integer from about 1 to about 1000, and R is a C8-C30 alkyl group. Examples of long-chain alcohols from which alkyl groups can be derived include decyl alcohol, lauryl alcohol, myristyl alcohol, cetyl alcohol, stearyl alcohol, oleyl alcohol, and similar alcohols. Examples of these surfactants include alkyl polyglucosides, in which case S is a glucose moiety, R is a C8-C20 alkyl group, and n is an integer from about 1 to about 9. Non-limiting examples of alkyl polyglucosides include decyl glucoside, coco glucoside, lauryl glucoside, and combinations thereof. Examples of commercially available surfactants include decyl polyglucosides and lauryl polyglucosides, available from Cognis (Ambler, Pa) under the trademark names APG® 325CS, APG® 600CS, and APG® 625CS. Also useful herein are sucrose ester surfactants such as sucrose cocoate and sucrose laurate, and alkyl polyglucosides, available from Dow Chemical Company (Houston, Tx) under the trademark names Triton® BG-10 and Triton® CG-110.

[0069] Other nonionic surfactants suitable for use in the present invention include, but are not limited to, glyceryl esters and polyglyceryl esters, glyceryl monoesters of C12-22 saturated, unsaturated and branched fatty acids, such as glyceryl monoesters, e.g., glyceryl oleate, glyceryl monostearate, glyceryl monopalmitate, glyceryl monobehenate and mixtures thereof, and polyglyceryl esters of C12-22 saturated, unsaturated and branched fatty acids, such as polyglyceryl-4 isostearate, polyglyceryl-3 oleate, polyglyceryl-2-sesquioleate, triglyceryl diisostearate, diglyceryl monooleate, tetraglyceryl monooleate and mixtures thereof. Non-limiting examples of glyceryl esters include glyceryl caprylate, glyceryl caprate, glyceryl cocoate, glyceryl laurate and combinations thereof.

[0070] Similarly, sorbitan esters are useful as nonionic surfactants in this specification. Sorbitan esters of saturated, unsaturated, and branched-chain fatty acids of C12-22 are useful in this specification. These sorbitan esters typically include mixtures of esters such as monoesters, diesters, and triesters. Typical examples of preferred sorbitan esters include sorbitan monolaurate (SPAN® 20), sorbitan monopalmitate (SPAN® 40), sorbitan monostearate (SPAN® 60), sorbitan tristearate (SPAN® 65), sorbitan monooleate (SPAN® 80), sorbitan trioleate (SPAN® 85), and sorbitan isostearate.

[0071] Similarly, suitable for use herein are alkoxylated derivatives of sorbitan esters, all of which are available from Uniqema, including but not limited to polyoxyethylene (20) sorbitan monolaurate (Tween® 20), polyoxyethylene (20) sorbitan monopalmitate (Tween® 40), polyoxyethylene (20) sorbitan monostearate (Tween® 60), polyoxyethylene (20) sorbitan monooleate (Tween® 80), polyoxyethylene (4) sorbitan monolaurate (Tween® 21), polyoxyethylene (4) sorbitan monostearate (Tween® 61), polyoxyethylene (5) sorbitan monooleate (Tween® 81), and mixtures thereof.

[0072] Similarly, alkylphenol ethoxylates are also suitable for use herein, but are not limited to nonylphenol ethoxylates (Tergitol® NP-4, NP-6, NP-7, NP-8, NP-9, NP-10, NP-11, NP-12, NP-13, NP-15, NP-30, NP-40, NP-50, NP-55, NP-70, available from Dow Chemical Company (Houston, TX)) and octylphenol ethoxylates (Triton® X-15, X-35, X-45, X-114, X-100, X-102, X-165, X-305, X-405, X-705, available from Dow Chemical Company (Houston, TX)).

[0073] Similarly, tertiary alkylamine oxides, including lauramine oxide and cocamine oxide, are also suitable for use herein.

[0074] Non-limiting examples of other anionic, zwitterionic, amphoteric, and nonionic additional surfactants suitable for use in hair care compositions are described in McCutcheon's "Emulsifiers and Detergents, 1989 Annual" (published by MCPublishing Co.), and in U.S. Patents 3,929,678, 2,658,072, 2,438,091, and 2,528,378, which are incorporated herein by reference in their entirety.

[0075] A suitable surfactant combination contains an average weight percent of alkyl branching of about 0.5% to about 30% by weight, alternatively about 1% to about 25% by weight, and alternatively about 2% to about 20% by weight. The surfactant combination can have a cumulative average weight percent of C8-C12 alkyl chain length of about 7.5% to about 25% by weight, alternatively about 10% to about 22.5% by weight, and alternatively about 10% to about 20% by weight. The surfactant combination can have an average C8-C12 / C13-C18 alkyl chain ratio of about 3 to about 200, alternatively about 25 to about 175.5, alternatively about 50 to about 150, and alternatively about 75 to about 125.

[0076] Cationic polymers The hair care composition further comprises cationic polymers. These cationic polymers may include at least one of the following: (a) cationic guar polymer, (b) cationic non-guar galactomannan polymer, (c) cationic tapioca polymer, (d) cationic copolymer of acrylamide monomer and cationic monomer, and / or (e) synthetic non-crosslinked cationic polymer which may or may not form a lyotropic liquid crystal when combined with a cleansing surfactant, and (f) cationic cellulose polymer. Furthermore, the cationic polymers may be mixtures of cationic polymers.

[0077] Hair care compositions may contain cationic guar polymers, which are cationically substituted galactomannan (guar) gum derivatives. The guar gum used in the preparation of these guar gum derivatives is typically obtained as a naturally occurring material from the seeds of the guar plant. The guar molecule itself is a linear mannan with alternating single-membered galactose units on mannose units, branched at regular intervals. The mannose units are linked to each other by β(1-4) glycosidic bonds. Galactose branching occurs via α(1-6) bonds. Cationic derivatives of guar gum are obtained by the reaction between the hydroxyl group of polygalactomannan and a reactive quaternary ammonium compound. The degree of substitution of the cationic group to the guar structure must be sufficient to provide the required cationic charge density described above.

[0078] In the present invention, cationic polymers include, but are not limited to, cationic guar polymers having a weight-average molecular weight of less than 2,200,000 g / mol, or about 150,000 to about 2,200,000 g / mol, or about 200,000 to about 2,200,000 g / mol, or about 250,000 to about 2,500,000 g / mol, or about 300,000 to about 1,200,000 g / mol, or about 700,000 (700,000 thousand) to about 1,000,000 g / mol. Furthermore, cationic guar polymers may have charge densities of approximately 0.2 to 2.2 meq / g, or approximately 0.3 to 2.0 meq / g, or approximately 0.4 to 1.8 meq / g, or approximately 0.5 meq / g to 1.8 meq / g.

[0079] The cationic guar polymer may have a weight average molecular weight of less than about 1,500,000 g / mol and has a charge density of about 0.1 meq / g to about 2.5 meq / g. The cationic guar polymer may have a weight average molecular weight of less than 900,000 g / mol, or about 150,000 to about 800,000 g / mol, or about 200,000 to about 700,000 g / mol, or about 300,000 to about 700,000 g / mol, or about 400,000 to about 600,000 g / mol, about 150,000 to about 800,000 g / mol, or about 200,000 to about 700,000 g / mol, or about 300,000 to about 700,000 g / mol, or about 400,000 to about 600,000 g / mol. The cationic guar polymer may have a charge density of about 0.2 to about 2.2 meq / g, or about 0.3 to about 2.0 meq / g, or about 0.4 to about 1.8 meq / g, or about 0.5 meq / g to about 1.5 meq / g.

[0080] The cationic guar polymer may be formed from a quaternary ammonium compound. The quaternary ammonium compound for forming the cationic guar polymer can conform to General Formula 1,

[0081]

Chemical formula

[0082]

Chemical formula

[0083]

Chemical formula

[0084] Cationic guar polymers can conform to general formula 4,

[0085] [ka] In the formula, R 8 It is guar gum, and R 4 , R 5 , R 6 , and R 7 The definition is the same as above, and Z is a halogen. Cationic guar polymers can conform to formula 5.

[0086] [ka]

[0087] Suitable cationic guar polymers include cationic guar gum derivatives such as guar hydroxypropyltrimonium chloride. The cationic guar polymer can be guar hydroxypropyltrimonium chloride. Specific examples of guar hydroxypropyltrimonium chloride include the Jaguar® series, commercially available from Solvay, such as Jaguar® C-500. Jaguar® C-500 has a charge density of 0.8 meq / g and a molecular weight of 500,000 g / mol. Another suitable guar hydroxypropyltrimonium chloride is guar hydroxypropyltrimonium chloride, available from Solvay as Jaguar® Optima, which has a charge density of approximately 1.3 meq / g and a molecular weight of approximately 500,000 g / mol. Other suitable guar hydroxypropyltrimonium chlorides include guar hydroxypropyltrimonium chloride, available from Solvay as Jaguar® Excel, which has a charge density of about 0.7 meq / g and a molecular weight of about 1,500,000 g / mol. Other suitable guar hydroxypropyltrimonium chlorides include guar hydroxypropyltrimonium chloride, available from ASI, which has a charge density of about 1.1 meq / g and a molecular weight of about 500,000 g / mol, and guar hydroxypropyltrimonium chloride, available from ASI, which has a charge density of about 1.5 meq / g and a molecular weight of about 500,000 g / mol. Other suitable guar hydroxypropyltrimonium chlorides include Hi-Care1000, available from Solvay, with a charge density of approximately 0.7 meq / g and a molecular weight of approximately 600,000 g / mol; N-Hance3269 and N-Hance3270, available from ASI, with a charge density of approximately 0.7 meq / g and a molecular weight of approximately 425,000 g / mol; and N-Hance3196, available from ASI, with a charge density of approximately 0.8 meq / g and a molecular weight of approximately 1,100,000 g / mol. AquaCat CG518 is available from ASI, with a charge density of approximately 0.9 meq / g and a molecular weight of approximately 50,000 g / mol.BF-13, a borate-free guar with a charge density of approximately 1.1 meq / g and a molecular weight of approximately 800,000, and BF-17, a borate-free guar with a charge density of approximately 1.5 meq / g and a molecular weight of approximately 800,000, are both available from ASI.

[0088] The hair care composition of the present invention may contain a galactomannan polymer derivative having a mannose-to-galactose ratio greater than 2:1 on a monomer-to-monomer basis, and this galactomannan polymer derivative is selected from the group consisting of cationic galactomannan polymer derivatives and amphoteric galactomannan polymer derivatives having a net positive charge. As used herein, the term "cationic galactomannan" refers to a galactomannan polymer to which a cationic group has been added. The term "amphoteric galactomannan" refers to a galactomannan polymer to which cationic and anionic groups have been added such that the polymer has a net positive charge.

[0089] Galactomannan polymers are found in the endosperm of leguminous plant seeds. Galactomannan polymers are composed of a combination of mannose monomers and galactose monomers. A galactomannan molecule is a linear mannan in which individual galactose units on a specific mannose unit are branched at regular intervals. The mannose units are linked to each other by β(1-4) glycosidic bonds. Galactose branching occurs via α(1-6) bonds. The mannose monomer to galactose monomer ratio varies depending on the plant species and is also influenced by climate. The non-guar galactomannan polymer derivatives of the present invention have a mannose to galactose ratio greater than 2:1 on a monomer-to-monomer basis. A preferred mannose to galactose ratio may be greater than about 3:1, and a mannose to galactose ratio may be greater than about 4:1. Analysis of the mannose to galactose ratio is well known in the art and is typically based on the measurement of galactose content.

[0090] The gums used in the preparation of non-guar-galactomannan polymer derivatives are typically obtained from naturally occurring materials such as plant seeds or beans. Examples of various non-guar-galactomannan polymers include, but are not limited to, tara gum (3 parts mannose / 1 part galactose), locust bean or carob (4 parts mannose / 1 part galactose), and cassia gum (5 parts mannose / 1 part galactose).

[0091] Non-guar galactomannan polymer derivatives may have molecular weights ranging from approximately 1,000 to approximately 10,000,000 and / or approximately 5,000 to approximately 3,000,000.

[0092] The hair care composition of the present invention may further contain a galactomannan polymer derivative having a cationic charge density of about 0.5 meq / g to about 7 meq / g. This galactomannan polymer derivative may have a cationic charge density of about 1 meq / g to about 5 meq / g. The degree of substitution of cationic groups to the galactomannan structure must be sufficient to provide the required cationic charge density.

[0093] Galactomannan polymer derivatives may be cationic derivatives of non-guar galactomannan polymers, which are obtained by the reaction of a hydroxyl group of a polygalactomannan polymer with a reactive quaternary ammonium compound. Suitable quaternary ammonium compounds for use in forming cationic galactomannan polymer derivatives include those conforming to the general formulas 1 to 5 defined above.

[0094] The cationic non-guargalactomannan polymer derivative formed from the above reagents is represented by general formula 6,

[0095] [ka] In the formula, R is gum. The cationic galactomannan derivative can be gum hydroxypropyltrimethylammonium chloride, which can be more specifically represented by the following general formula 7.

[0096] [ka]

[0097] Alternatively, the galactomannan polymer derivative may be an amphoteric galactomannan polymer derivative having a net positive charge, which can be obtained when the cationic galactomannan polymer derivative further contains an anionic group.

[0098] Cationic non-guargalactomannan can have a mannose-to-galactose ratio greater than approximately 4:1, molecular weights of approximately 1,000 g / mol to approximately 10,000,000 g / mol, and / or approximately 50,000 g / mol to approximately 1,000,000 g / mol, and / or approximately 100,000 g / mol to approximately 900,000 g / mol, and / or approximately 150,000 g / mol to approximately 400,000 g / mol, and cation charge densities of approximately 1 meq / g to approximately 5 meq / g, and / or 2 meq / g to approximately 4 meq / g, and can be obtained from the plant Cassia.

[0099] Hair care compositions may contain water-soluble cationic-modified starch polymers. As used herein, the term “cationically modified starch” refers to starch to which cationic groups have been added before it is broken down into smaller molecular weights, or starch to which cationic groups have been added after it has been modified to reach a desired molecular weight. The definition of the term “cationically modified starch” also includes amphoteric modified starch. The term “amphoteric modified starch” refers to starch hydrolysates to which cationic and anionic groups have been added.

[0100] The cationic modified starch polymers disclosed herein have a bound nitrogen percentage of about 0.5% to about 4%.

[0101] The cation-modified starch polymer used in the hair care composition may have a molecular weight of approximately 850,000 g / mol to approximately 1,500,000 g / mol, and / or approximately 900,000 g / mol to approximately 1,500,000 g / mol.

[0102] The hair care composition may contain a cationic modified starch polymer having a charge density of about 0.2 meq / g to about 5 meq / g and / or about 0.2 meq / g to about 2 meq / g. Chemical modifications to obtain such charge densities include, but are not limited to, the addition of amino groups and / or ammonium groups to the starch molecule. Non-limiting examples of these ammonium groups include substituents such as hydroxypropyltrimonium chloride, trimethylhydroxypropylammonium chloride, dimethylstearylhydroxypropylammonium chloride, and dimethyldodecylhydroxypropylammonium chloride. See Solarek, DB, Cationic Starches in Modified Starches: Properties and Uses, Wurzburg, OB, Ed., CRC Press, Inc. (Boca Raton, Fla.), 1986, pp 113-125. The cationic group may be added to the starch before it is broken down into smaller molecular weights, or it may be added after such modification.

[0103] Cationically modified starch polymers generally have a degree of cationic substitution of approximately 0.2 to 2.5. As used herein, the “degree of substitution” of a cationically modified starch polymer is the average number of hydroxyl groups on each glucose anhydride unit derivatized by the substituent. Since each glucose anhydride unit has three possible hydroxyl groups available for substitution, the maximum possible degree of substitution is 3. The degree of substitution is expressed on a molar basis as the number of moles of substituents per mole of glucose anhydride unit. The degree of substitution can be determined using proton nuclear magnetic resonance spectroscopy ("sup.1H NMR"), a method well known in the art. Suitable sup.1H NMR methods include those described in "Observation on NMR Spectra of Starches in Dimethyl Sulfoxide, Iodine-Complexing, and Solvating in Water-Dimethyl Sulfoxide," Qin-Ji Peng and Arthur S. Perlin, Carbohydrate Research, 160 (1987), 57-72, and "An Approach to the Structural Analysis of Oligosaccharides by NMR Spectroscopy," J. Howard Bradbury and J. Grant Collins, Carbohydrate Research, 71 (1979), 15-25.

[0104] The starch source before chemical modification can be selected from a variety of sources, including tubers, legumes, cereals, and grains. Non-limiting examples of starches from this source include corn starch, wheat starch, rice starch, waxy corn starch, oat starch, cassava starch, waxy barley, waxy rice starch, glutenous rice starch, amioca, potato starch, tapioca starch, oat starch, sago starch, glutinous rice, or mixtures thereof.

[0105] Cationically modified starch polymers can be selected from decomposed cationic corn starch, cationic tapioca, cationic potato starch, and mixtures thereof. Alternatively, cationically modified starch polymers are cationic corn starch and cationic tapioca.

[0106] Starch may undergo one or more additional modifications before or after being broken down into smaller molecular weight molecules. Examples of these modifications include crosslinking, stabilization reactions, phosphorylation reactions, and hydrolysis. Examples of stabilization reactions include alkylation and esterification.

[0107] Cationically modified starch polymers may be incorporated into compositions in the form of hydrolyzed starch (e.g., acid, enzyme, or alkaline decomposition), oxidized starch (e.g., peroxide, peracid, hypochlorite, alkali, or any other oxidizing agent), physically / mechanically decomposed starch (e.g., by inputting thermomechanical energy into a processing apparatus), or a combination thereof.

[0108] The optimal form of starch is one that readily dissolves in water and forms a substantially clear aqueous solution (approximately 80% transmittance at 600 nm). The transmittance of the composition is measured by ultraviolet / visible (UV / VIS) absorbance spectroscopy, which measures the absorption or transmittance of the sample to UV / VIS light using a Gretag Macbeth Colorimeter Color i 5, according to the relevant instructions. A light wavelength of 600 nm has been shown to be suitable for characterizing the transparency of cosmetic compositions.

[0109] Cationic modified starches suitable for use in hair care compositions are available from known starch suppliers. Similarly, nonionic modified starches that can be further derivatized to cationic modified starches are suitable for use in hair care compositions, as is known in the art. Other suitable modified starch starting materials may be quaternized, as is known in the art, to produce cationic modified starch polymers suitable for use in hair care compositions.

[0110] Starch decomposition procedure: A starch slurry can be prepared by mixing granular starch in water. Raise the temperature to approximately 35°C. Next, add an aqueous potassium permanganate solution to a concentration of approximately 50 ppm based on the starch. Raise the pH to approximately 11.5 with sodium hydroxide, stirring the slurry thoroughly to prevent starch from settling. Next, add a 30% solution of hydrogen peroxide diluted with water until the peroxide concentration based on the starch is approximately 1%. Subsequently, return the pH to approximately 11.5 by adding additional sodium hydroxide. This reaction takes approximately 1 to 20 hours to complete. Next, neutralize the mixture with dilute hydrochloric acid. The decomposed starch is recovered by filtration, then washed and dried.

[0111] The hair care composition may include a cationic copolymer of an acrylamide monomer and a cationic monomer, which has a charge density of about 1.0 meq / g to about 3.0 meq / g. The cationic copolymer may be a synthetic cationic copolymer of an acrylamide monomer and a cationic monomer.

[0112] Cationic copolymers may include the following:

[0113] (i) The acrylamide monomer of the following formula AM:

[0114] [ka] In the formula, R 9 H or C 1~4It is alkyl, R 10 and R 11 H and C are independent of each other. 1~4 Selected from the group consisting of alkyl, CH2OCH3, CH2OCH2CH(CH3)2, and phenyl, or together C 3~6 It is a cycloalkyl group. (ii) Cationic monomers conforming to the following formula CM:

[0115] [ka] In the formula, k=1, v, v', and v'' are each independent integers from 1 to 6, w is 0, or an integer from 1 to 10, and X - It is an anion.

[0116] The cationic monomer conforms to formula CM, where k=1, v=3 and w=0, z=1, and X - is Cl - And, it can form the following structure.

[0117] [ka] The above structure is sometimes called a diquat. Alternatively, a cationic monomer can be fitted to formula CM, where v and v'' are 3, v'=1, w=1, y=1, and X - is Cl - For example, the following:

[0118] [ka] The structure described above is sometimes referred to as a triquat.

[0119] Suitable acrylamide monomers include, but are not limited to, acrylamide or methacrylamide.

[0120] The cationic copolymer (b) may be AM:TRIQUAT, which is a copolymer of acrylamide and 1,3-propanediaminium,N-[2-[[[dimethyl[3-[(2-methyl-1-oxo-2-propenyl)amino]propyl]ammonio]acetyl]amino]ethyl]2-hydroxy-N,N,N',N',N'-pentamethyl-,trichloride. AM:TRIQUAT is also known as polyquaternium 76 (PQ76). AM:TRIQUAT may have a charge density of 1.6 meq / g and a molecular weight of 1,100,000 g / mol.

[0121] Furthermore, the cationic copolymer may be a copolymer of an acrylamide monomer and a cationic monomer, and the cationic monomer is selected from the group consisting of dimethylaminoethyl (meth)acrylate, dimethylaminopropyl (meth)acrylate, ditertio-butylaminoethyl (meth)acrylate, dimethylaminomethyl (meth)acrylamide, dimethylaminopropyl (meth)acrylamide; ethyleneimine, vinylamine, 2-vinylpyridine, 4-vinylpyridine; trimethylammonium ethyl (meth)acrylate chloride, trimethylammonium ethyl (meth)acrylate methyl sulfate, dimethylammonium ethyl (meth)acrylate benzyl chloride, 4-benzoylbenzyldimethylammonium ethyl acrylate chloride, trimethylammonium ethyl (meth)acrylamide chloride, trimethylammonium propyl (meth)acrylamide chloride, vinylbenzyltrimethylammonium chloride, diallyldimethylammonium chloride, and mixtures thereof.

[0122] The cationic copolymer may contain cationic monomers selected from the group consisting of cationic monomers including trimethylammonium ethyl (meth)acrylate chloride, trimethylammonium ethyl (meth)acrylate methyl sulfate, dimethylammonium ethyl (meth)acrylate benzyl chloride, 4-benzoylbenzyldimethylammonium ethyl acrylate chloride, trimethylammonium ethyl (meth)acrylamide chloride, trimethylammonium propyl (meth)acrylamide chloride, vinylbenzyltrimethylammonium chloride, and mixtures thereof.

[0123] The cationic copolymer may be water-soluble. The cationic copolymer is formed from (1) a copolymer of (meth)acrylamide and a cationic monomer mainly composed of (meth)acrylamide, and / or a cationic monomer that is stable against hydrolysis, and (2) a copolymer of (meth)acrylamide, a monomer mainly composed of a cationic (meth)acrylic acid ester, and a monomer mainly composed of (meth)acrylamide, and / or a cationic monomer that is stable against hydrolysis. The monomer mainly composed of a cationic (meth)acrylic acid ester may be a cationic ester of (meth)acrylic acid containing a quaternary nitrogen atom. The cationic ester of (meth)acrylic acid containing a quaternary nitrogen atom may be a dialkylaminoalkyl (meth)acrylate that has been quaternized at C1-C3 in the alkyl group and alkylene group. Suitable cationized esters of (meth)acrylic acid containing a quaternary nitrogen atom can be selected from the group consisting of ammonium salts of dimethylaminomethyl (meth)acrylate, dimethylaminoethyl (meth)acrylate, dimethylaminopropyl (meth)acrylate, diethylaminomethyl (meth)acrylate, diethylaminoethyl (meth)acrylate, and diethylaminopropyl (meth)acrylate, all of which are quaternized with methyl chloride. The cationized ester of (meth)acrylic acid containing a quaternary nitrogen atom may be dimethylaminoethyl acrylate (ADAME-Quat), which is quaternized with an alkyl halide, or with methyl chloride, benzyl chloride, or dimethyl sulfate. When the cationic monomer is mainly (meth)acrylamide, it may be dialkylaminoalkyl (meth)acrylamide quaternized at C1-C3 in the alkyl and alkylene groups, or dimethylaminopropyl acrylamide quaternized with an alkyl halide, or with methyl chloride, benzyl chloride, or dimethyl sulfate.

[0124] Suitable cationic monomers mainly composed of (meth)acrylamide include dialkylaminoalkyl(meth)acrylamides that have been quaternized at the C1-C3 level within the alkyl and alkylene groups. Cationic monomers mainly composed of (meth)acrylamide may be dimethylaminopropylacrylamides that have been quaternized with alkyl halides, particularly methyl chloride, benzyl chloride, or dimethyl sulfate.

[0125] Cationic monomers may be cationic monomers that are stable against hydrolysis. Besides dialkylaminoalkyl(meth)acrylamide, cationic monomers stable against hydrolysis can be any monomer that can be considered stable against the OECD hydrolysis test. Cationic monomers can be stable against hydrolysis, and cationic monomers stable against hydrolysis can be selected from the group consisting of diallyldimethylammonium chloride and water-soluble cationic styrene derivatives.

[0126] The cationic copolymer may be a terpolymer of acrylamide, 2-dimethylammonium ethyl (meth)acrylate (ADAME-Q) quaternized with methyl chloride, and 3-dimethylammonium propyl (meth)acrylamide (DIMAPA-Q) quaternized with methyl chloride. The cationic copolymer can be formed from acrylamide and acrylamidopropyltrimethylammonium chloride, which has a charge density of about 1.0 meq / g to about 3.0 meq / g.

[0127] Cationic copolymers can have charge densities of approximately 1.1 meq / g to approximately 2.5 meq / g, or approximately 1.1 meq / g to approximately 2.3 meq / g, or approximately 1.2 meq / g to approximately 2.2 meq / g, or approximately 1.2 meq / g to approximately 2.1 meq / g, or approximately 1.3 meq / g to approximately 2.0 meq / g, or approximately 1.3 meq / g to approximately 1.9 meq / g.

[0128] Cationic copolymers can have molecular weights of approximately 100,000 g / mol to approximately 1,500,000 g / mol, or approximately 300,000 g / mol to approximately 1,500,000 g / mol, or approximately 500,000 g / mol to approximately 1,500,000 g / mol, or approximately 700,000 g / mol to approximately 1,000,000 g / mol, or approximately 900,000 g / mol to approximately 1,200,000 g / mol.

[0129] The cationic copolymer may be trimethylammoniopropylmethacrylamide chloride-N-acrylamide copolymer, also known as AM:MAPTAC. AM:MAPTAC may have a charge density of about 1.3 meq / g and a molecular weight of about 1,100,000 g / mol. The cationic copolymer may also be AM:ATPAC. AM:ATPAC may have a charge density of about 1.8 meq / g and a molecular weight of 1,100,000 g / mol.

[0130] (a) Cationic synthetic polymers The hair care composition may contain a cationic synthetic polymer, and the cationic synthetic polymer is i) One or more cationic monomer units, and optionally, ii) One or more monomer units having a negative charge, and / or iii) Can be formed from nonionic monomers. Here, the subsequent charge of the copolymer is positive. The ratio of these three types of monomers is represented by "m", "p", and "q", where "m" is the number of cationic monomers, "p" is the number of negatively charged monomers, and "q" is the number of nonionic monomers.

[0131] Cationic polymers may be water-soluble or dispersible, non-crosslinked synthetic cationic polymers having the following structure:

[0132] [ka] In the formula, A may be one or more of the following cationic moieties.

[0133] [ka] In the formula, @ is an amide, alkylamide, ester, ether, alkyl, or alkylaryl. Y is a C1-C22 alkyl, alkoxy, alkylidene, alkyl, or aryloxy. Ψ is a C1-C22 alkyl, alkyloxy, alkylaryl, or alkylaryloxy. Z is a C1-C22 alkyl, alkyloxy, aryl, or aryloxy. R1 is a linear or branched alkyl group consisting of H, C1-C4. s is 0 or 1, and n is 0 or ≥ 1. T and R7 are C1-C22 alkyl groups. X - These are halogens, hydroxides, alkoxides, sulfates, or alkyl sulfates.

[0134] In the above structure, a negatively charged monomer is defined by having R2' be H, a linear or branched alkyl group of C1-C4, and R3 being as follows:

[0135] [ka] In the formula, D is O, N, or S. Q is either NH2 or O. u is 1 to 6, t is between 0 and 1. J is an oxygenated functional group containing the following elements P, S, and C.

[0136] In the above structure, the nonionic monomer is defined by R2'' being a linear or branched alkyl group of H, C1-C4, and R6 being a linear or branched alkyl group, alkylaryl group, aryloxy group, alkyloxy group, or alkylaryloxy group, and β is defined as follows:

[0137] [ka] In the formula, G' and G'' are independently O, S, or NH, and L is either 0 or 1.

[0138] Examples of cationic monomers include aminoalkyl (meth)acrylates, (meth)aminoalkyl (meth)acrylamides; monomers containing at least one secondary, tertiary, or quaternary amine functional group, or a heterocyclic group containing a nitrogen atom, vinylamine, or ethyleneimine; diallyldialkylammonium salts; mixtures thereof, salts thereof, and macromonomers derived therefrom.

[0139] Further examples of cationic monomers include dimethylaminoethyl (meth)acrylate, dimethylaminopropyl (meth)acrylate, ditertio-butylaminoethyl (meth)acrylate, dimethylaminomethyl (meth)acrylamide, dimethylaminopropyl (meth)acrylamide, ethyleneimine, vinylamine, 2-vinylpyridine, 4-vinylpyridine, trimethylammonium ethyl (meth)acrylate chloride, trimethylammonium ethyl (meth)acrylate methyl sulfate, dimethylammonium ethyl (meth)acrylate benzyl chloride, 4-benzoylbenzyldimethylammonium ethyl acrylate chloride, trimethylammonium ethyl (meth)acrylamide chloride, trimethylammonium propyl (meth)acrylamide chloride, vinylbenzyltrimethylammonium chloride, and diallyldimethylammonium chloride.

[0140] Suitable cationic monomers include those of formula -NR3 +Examples include quaternary ammonium groups containing anions (counterions), where R is the same or different and represents a hydrogen atom, an alkyl group containing 1 to 10 carbon atoms, or a benzyl group, and optionally having a hydroxyl group. Examples of anions include halides such as chlorides and bromides, sulfates, hydrosulfates, alkyl sulfates (e.g., containing 1 to 6 carbon atoms), phosphates, citrates, formates, and acetates.

[0141] Suitable cationic monomers include trimethylammonium ethyl (meth)acrylate chloride, trimethylammonium ethyl (meth)acrylate methyl sulfate, dimethylammonium ethyl (meth)acrylate benzyl chloride, 4-benzoylbenzyldimethylammonium ethyl acrylate chloride, trimethylammonium ethyl (meth)acrylamide chloride, trimethylammonium propyl (meth)acrylamide chloride, and vinylbenzyltrimethylammonium chloride.

[0142] Further preferred cationic monomers include trimethylammonium propyl (meth)acrylamide chloride.

[0143] Examples of negatively charged monomers include α-ethylenically unsaturated monomers containing a phosphate or phosphonate group, α-ethylenically unsaturated monocarboxylic acids, monoalkyl esters of α-ethylenically unsaturated dicarboxylic acids, monoalkylamides of α-ethylenically unsaturated dicarboxylic acids, α-ethylenically unsaturated compounds containing a sulfonic acid group, and salts of α-ethylenically unsaturated compounds containing a sulfonic acid group.

[0144] Suitable monomers having a negative charge include acrylic acid, methacrylic acid, vinyl sulfonic acid, salts of vinyl sulfonic acid, vinylbenzenesulfonic acid, salts of vinylbenzenesulfonic acid, α-acrylamidomethylpropanesulfonic acid, salts of α-acrylamidomethylpropanesulfonic acid, 2-sulfoethyl methacrylate, salts of 2-sulfoethyl methacrylate, acrylamide-2-methylpropanesulfonic acid (AMPS), salts of acrylamide-2-methylpropanesulfonic acid, and styrenesulfonate (SS).

[0145] Examples of nonionic monomers include vinyl acetate, amides of α-ethylenically unsaturated carboxylic acids, esters of α-ethylenically unsaturated monocarboxylic acids with hydrogenated or fluorinated alcohols, polyethylene oxide (meth)acrylate (i.e., polyethoxylated (meth)acrylic acid), monoalkyl esters of α-ethylenically unsaturated dicarboxylic acids, monoalkylamides of α-ethylenically unsaturated dicarboxylic acids, vinyl nitriles, vinylamine amides, vinyl alcohols, vinylpyrrolidone, and vinyl aromatic compounds.

[0146] Suitable nonionic monomers include styrene, acrylamide, methacrylamide, acrylonitrile, methyl acrylate, ethyl acrylate, n-propyl acrylate, n-butyl acrylate, methyl methacrylate, ethyl methacrylate, n-propyl methacrylate, n-butyl methacrylate, 2-ethyl-hexyl acrylate, 2-ethyl-hexyl methacrylate, 2-hydroxyethyl acrylate, and 2-hydroxyethyl methacrylate.

[0147] As long as the polymer maintains its solubility or dispersibility in water, the hair care composition, or the coacervate phase of the hair care composition, and as long as the counterion is physically and chemically compatible with the essential components of the hair care composition, or otherwise does not excessively impair the performance, stability, or aesthetics of the product, the anionic counterion (X-) associated with the synthetic cationic polymer may be any known counterion. Non-limiting examples of such counterions include halide ions (e.g., chlorine, fluorine, bromine, iodine), sulfate ions, and methyl sulfate ions.

[0148] The cationic polymers described herein may help provide a substitute hydrophobic F layer to damaged hair, particularly chemically treated hair. A microscopically thin F layer helps retain moisture and prevent further damage while providing natural weather resistance. Chemical treatment damages the hair cuticle, causing the protective F layer to peel off. As the F layer peels off, the hair becomes more hydrophilic. It has been found that applying lyotropic liquid crystal to chemically treated hair makes it even more hydrophobic, resulting in an appearance and feel similar to untreated hair. While not bound by any particular theory, it is believed that lyotropic liquid crystal complexes form a hydrophobic layer or film, coating and protecting the hair fibers in a similar way to how the natural F layer protects hair. The hydrophobic layer restores the hair to a healthier state overall, similar to untreated hair. Lyotropic liquid crystals are formed by combining the synthetic cationic polymers described herein with the anionic cleansing surfactant components described above in hair care compositions. The charge density of the synthetic cationic polymers is relatively high. It should be noted that some synthetic polymers with relatively high cationic charge densities do not form lyotropic liquid crystals, mainly due to their unusually linear charge densities. Such synthetic cationic polymers are described in International Publication No. 94 / 06403 (Reich et al.). The synthetic polymers described herein can be incorporated into stable hair care compositions to improve the conditioning performance of damaged hair.

[0149] Cationic synthetic polymers capable of forming lyotropic liquid crystals may have cationic charge densities of about 2 meq / gm to about 7 meq / gm, and / or about 3 meq / gm to about 7 meq / gm, and / or about 4 meq / gm to about 7 meq / gm. The cationic charge density may be about 6.2 meq / gm. These polymers also have molecular weights of about 1,000 to about 5,000,000, and / or about 10,000 to about 1,500,000, and / or about 100,000 to about 1,500,000.

[0150] Cationic synthetic polymers that provide conditioning and enhanced adhesion of beneficial agents, but do not necessarily form lyotropic liquid crystals, may have cation charge densities of about 0.7 meq / gm to about 7 meq / gm, and / or about 0.8 meq / gm to about 5 meq / gm, and / or about 1.0 meq / gm to about 3 meq / gm. These polymers also have molecular weights of about 1,000 to about 1,500,000, about 10,000 to about 1,500,000, and about 100,000 to about 1,500,000.

[0151] A preferred cationic cellulose polymer is a salt of hydroxyethyl cellulose reacted with a trimethylammonium substituted epoxide, which is referred to in the CTFA as Polyquaternium 10 and is available from Dow / Amerchol Corp. (Edison, NJ, USA) in the Polymer LR, JR, and KG series polymers. Non-limiting examples include JR-400, JR-125, JR-30M, KG-30M, JP, LR-400, and mixtures thereof. Another preferred type of cationic cellulose is a polymeric quaternary ammonium salt of hydroxyethyl cellulose reacted with a lauryldimethylammonium substituted epoxide, which is referred to in the CTFA as Polyquaternium 24. These materials are available from Dow / Amerchol Corp. under the trade name Polymer LM-200. Other suitable types of cationic cellulose include polymeric quaternary ammonium salts of hydroxyethyl cellulose, reacted with lauryldimethylammonium substituted epoxides and trimethylammonium substituted epoxides, known in the CTFA as polyquaternium-67. These materials are available from Dow / Amerchol Corp. under the trade names SoftCAT Polymer SL-5, SoftCAT Polymer SL-30, Polymer SL-60, Polymer SL-100, Polymer SK-L, Polymer SK-M, Polymer SK-MH, and Polymer SK-H.

[0152] Suitable cationic cellulose polymers may have a cationic charge density of about 0.5 meq / gm to about 2.5 meq / gm, and / or about 0.6 meq / gm to about 2.2 meq / gm, and / or about 0.6 meq / gm to about 2.0 meq / gm. Furthermore, the cationic charge density may be about 1.9 meq / gm. This polymer also has a molecular weight of about 200,000 to about 3,000,000, and / or about 300,000 to about 2,200,000, and / or about 1,000,000 to about 2,200,000, and / or about 300,000 to about 1,500,000. Cationic cellulose polymers may have a cation charge density of approximately 1.7 to approximately 2.1 meq / g and a molecular weight of approximately 1,000,000 to approximately 2,000,000.

[0153] The concentration of the cationic polymer is in the range of approximately 0.01% to 5% by weight, approximately 0.08% to 3% by weight, approximately 0.1% to 2% by weight, and / or approximately 0.2% to 1% by weight of the hair care composition.

[0154] Thickening polymer The hair care composition may contain a thickening polymer to increase the viscosity of the composition. A suitable thickening polymer can be used. The hair care composition may contain about 0.1% to about 10% of the thickening polymer, about 0.25% to about 10% of the thickening polymer, about 0.5% to about 8% of the thickening polymer, about 1.0% to about 5% of the thickening polymer, and about 1% to about 4% of the thickening polymer. The thickening polymer modifier may be a polyacrylate or polyacrylamide thickener. The thickening polymer may be anionic thickening polymer.

[0155] The hair care composition may contain a thickening polymer that is a homopolymer based on acrylic acid, methacrylic acid, or other related derivatives, and non-limiting examples include polyacrylate, polymethacrylate, polyethyl acrylate, and polyacrylamide.

[0156] The thickening polymer may be an alkali-swellable and hydrophobic-modified alkali-swellable acrylic copolymer or methacrylate copolymer, and non-limiting examples include acrylic acid / acrylonitrogen copolymer, acrylate / steareth-20 itaconate copolymer, acrylate / ceteth-20 itaconate copolymer, acrylate / aminoacrylate / C10-30 alkylPEG-20 itaconate copolymer, acrylate / aminoacrylate copolymer, acrylate / steareth-20 methacrylate copolymer, and Examples include acrylate / beheneth-25 methacrylate copolymer, acrylate / steareth-20 methacrylate crosspolymer, acrylate / beheneth-25 methacrylate / HEMA crosspolymer, acrylate / vinyl neodecanoate crosspolymer, acrylate / vinyl isodecanoate crosspolymer, acrylate / palmeta-25 acrylate copolymer, acrylic acid / acrylamidomethylpropanesulfonic acid copolymer, and acrylate / C10-C30 alkyl acrylate crosspolymer.

[0157] The thickening polymer may be a soluble crosslinked acrylic polymer, and a non-limiting example is a carbomer.

[0158] The thickening polymer may be an associative polymer thickener, and non-limiting examples include hydrophobic modified alkali swelling emulsions, and non-limiting examples include hydrophobic modified polypolyacrylates; hydrophobic modified polyacrylic acids, and hydrophobic modified polyacrylamides; hydrophobic modified polyethers, and these materials may have hydrophobic substances that can be selected from cetyl, stearyl, oleyl, and combinations thereof.

[0159] The thickening polymer may be polyvinylpyrrolidone, crosslinked polyvinylpyrrolidone, or a derivative. The thickening polymer may also be polyvinyl alcohol or a derivative. It is a thickening polymer combining polyethyleneimine and a derivative.

[0160] The thickening polymer can be an alginate-based material, and non-limiting examples include sodium alginate and propylene glycol alginate.

[0161] The thickening polymer may be a polyurethane polymer, and non-limiting examples include hydrophobic modified alkoxylated urethane polymers, and non-limiting examples include PEG-150 / decyl alcohol / SMDI copolymer, PEG-150 / stearyl alcohol / SMDI copolymer, and polyurethane-39.

[0162] The thickening polymers may be associative polymer thickeners, and non-limiting examples include hydrophobic modified cellulose derivatives and hydrophilic moieties of repeating ethylene oxide groups with repeating units of about 10 to about 300, about 30 to about 200, and about 40 to about 150. Non-limiting examples of this category include PEG-120-methyl glucose dioleate, PEG-(40 or 60) sorbitan tetraoleate, PEG-150 pentaerythrityl tetrastearate, PEG-55 propylene glycol oleate, and PEG-150 distearate.

[0163] Thickening polymers can be cellulose and its derivatives, and non-limiting examples include microcrystalline cellulose, carboxymethylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose, methylcellulose, ethylcellulose; nitrocellulose; cellulose sulfate; cellulose powder; and hydrophobic modified cellulose.

[0164] The thickening polymers may be guar and guar derivatives, and non-limiting examples include hydroxypropyl guar and hydroxypropyl guar hydroxypropyltrimonium chloride.

[0165] The thickening polymer may be polyethylene oxide, polypropylene oxide, or POE-PPO copolymer.

[0166] The thickening polymer may be a polyalkylene glycol characterized by the following general formula:

[0167] [ka] In the formula, R is hydrogen, methyl, or a mixture thereof, and is more specifically hydrogen, and n is an integer between 2,000 and 180,000 on average, or between 7,000 and 90,000, or between 7,000 and 45,000. Non-limiting examples of this category include PEG-7M, PEG-14M, PEG-23M, PEG-25M, PEG-45M, PEG-90M, or PEG-100M.

[0168] The thickening polymer can be silica, and non-limiting examples include fumed silica, precipitated silica, and silicone surface-treated silica.

[0169] The thickening polymer can be a water-swellable clay, and non-limiting examples include laponite, bentonite, montmorillonite, smectite, and hectonite.

[0170] The thickening polymer can be rubber, and non-limiting examples include xanthan gum, guar gum, hydroxyprolyl guar gum, gum arabic, tragacanth, galactan, carob gum, karaya gum, and locust bean gum.

[0171] The thickening polymers may be dibenzylidenesorbitol, carrageenan, pectin, agar, quince seed (Cydonia oblonga Mill), starch (derived from rice, corn, potato, wheat, etc.), starch derivatives (e.g., carboxymethyl starch, methylhydroxypropyl starch), algal extracts, dextran, succinoglucan, and pulleran.

[0172] Non-limiting examples of thickening polymers include acrylamide / ammonium acrylate copolymer (and) polyisobutene (and) polysorbate 20; acrylamide / sodium acryloyldimethyltaurate copolymer / isohexadecane / polysorbate 80; ammonium acryloyldimethyltaurate / VP copolymer; sodium acrylate / sodium acryloyldimethyltaurate copolymer; acrylate copolymer; acrylate crosspolymer-4; acrylate crosspolymer-3; acrylate / beheneth-25 methacrylate copolymer; acrylate / C10-C30 alkyl acrylate crosspolymer; acrylate / steareth-20 itaconate copolymer; poly Examples include ammonium acrylate / isohexadecane / PEG-40 castor oil; carbomer, sodium carbomer, cross-linked polyvinylpyrrolidone (PVP), polyacrylamide / C13-14 isoparaffin / laureth-7, polyacrylate 13 / polyisobutene / polysorbate 20, polyacrylate crosspolymer-6, polyamide-3, polyquaternium-37 (and) hydrogenated polydecene (and) trideceth-6, acrylamide / sodium acryloyldimethyltaurate / acrylic acid copolymer, sodium acrylate / acryloyldimethyltaurate / dimethylacrylamide crosspolymer (and) isohexadecane (and) polysorbate 60, and sodium polyacrylate.Examples of commercially available thickening polymers include ACULYN® 28, ACULYN® 33, ACULYN® 88, ACULYN® 22, ACULYN® Excel, Carbopol® AquaSF-1, Carbopol® ETD2020, Carbopol® Ultrez20, Carbopol® Ultrez21, Carbopol® Ultrez10, and Carbopol® Ultrez3. Examples include 0, Carbopol® 1342, Carbopol® AquaSF-2 polymer, Sepigel® 305, Simulgel® 600, SepimaxZen, Carbopol® SMART1000, Rheocare® TTA, Rheomer® SC-Plus, STRUCTURE® PLUS, Aristoflex® AVC, Stabylen 30, and combinations thereof.

[0173] Gel Network In the present invention, a gel network may be present. The gel network components of the present invention include at least one aliphatic amphiphilic substance. As used herein, "aliphatic amphiphilic substance" means alkyl, alkenyl (containing up to three double bonds), alkyl aromatic, or C 12 ~C 70 This refers to a compound having a hydrophobic terminal group defined as a branched alkyl group of length 1, and a hydrophilic terminal group that does not make the compound water-soluble, and the compound also has a net neutral charge at the pH of the shampoo composition.

[0174] The shampoo composition of the present invention contains an aliphatic amphiphilic substance as part of a pre-formed dispersed gel network phase in amounts of about 0.05% to about 14% by weight, about 0.5% to about 10% by weight, and about 1% to about 8% by weight of the shampoo composition.

[0175] According to the present invention, a suitable aliphatic amphiphilic substance, or a suitable mixture of two or more aliphatic amphiphilic substances, has a melting point of at least about 27°C. When used herein, the melting point is as defined in USPharmacopeia, USP-NF General Chapter <741> The melting point can be measured using the standard melting point method described in "Melting range or temperature". The melting point of a mixture of two or more materials is measured by mixing the two or more materials at a temperature above the individual melting points of the materials, and then cooling the mixture. If the resulting composite is a homogeneous solid below about 27°C, the mixture has a melting point suitable for use in the present invention. A mixture of two or more aliphatic amphiphilic materials, including at least one aliphatic amphiphilic material whose individual melting point is below about 27°C, is also suitable for use in the present invention as long as the combined melting point of the mixture is at least about 27°C.

[0176] Suitable aliphatic amphiphilic substances of the present invention include fatty alcohols, alkoxylated fatty alcohols, fatty phenols, alkoxylated fatty phenols, fatty amides, alkoxylated fatty amides, fatty amines, fatty alkylamides, alkylamines, fatty alkoxylated amines, fatty carbamates, fatty amine oxides, fatty acids, alkoxylated fatty acids, fatty diesters, fatty sorbitan esters, fatty sugar esters, methyl glucoside esters, fatty glycol esters, mono, di, and triglycerides, polyglycerin fatty esters, alkylglyceryl ethers, propylene glycol fatty acid esters, cholesterol, ceramides, fatty silicone waxes, fatty glucose amides, and phospholipids, as well as mixtures thereof.

[0177] The shampoo composition may contain an aliphatic alcohol gel network. These gel networks are formed by combining an aliphatic alcohol and a surfactant in ratios of approximately 1:1 to approximately 40:1, approximately 2:1 to approximately 20:1, and / or approximately 3:1 to approximately 10:1. The formation of the gel network involves heating an aqueous dispersion of the aliphatic alcohol together with the surfactant to a temperature above the melting point of the aliphatic alcohol. During this mixing process, the aliphatic alcohol melts and partitions the surfactant into aliphatic alcohol droplets. The surfactant carries water into the aliphatic alcohol along with the surfactant. This transforms the isotropic aliphatic alcohol droplets into liquid crystal phase droplets. When this mixture is cooled to a temperature below the chain melting point, the liquid crystal phase is converted into a solid crystalline gel network. The gel network contributes to the stabilizing effect on cosmetic creams and hair conditioners. In addition, they provide a tuned feel to hair conditioners.

[0178] Aliphatic alcohols may be present in the aliphatic alcohol gel network at concentrations ranging from approximately 0.05% to approximately 14% by weight. For example, aliphatic alcohols may be present in amounts ranging from approximately 1% to approximately 10% by weight, and / or approximately 6% to approximately 8% by weight.

[0179] Aliphatic alcohols useful in this specification include those having about 10 to about 40 carbon atoms, about 12 to about 22 carbon atoms, about 16 to about 22 carbon atoms, and / or about 16 to about 18 carbon atoms. These aliphatic alcohols may be straight-chain or branched-chain alcohols, and may be saturated or unsaturated. Non-limiting examples of aliphatic alcohols include cetyl alcohol, stearyl alcohol, behenyl alcohol, and mixtures thereof. Mixtures of cetyl alcohol and stearyl alcohol in a ratio of about 20:80 to about 80:20 are preferred.

[0180] Preparation of the gel network: Fill a container with water and heat the water to approximately 74°C. Add cetyl alcohol, stearyl alcohol, and SLES surfactant to the heated water. After addition, pass the resulting mixture through a heat exchanger and cool the mixture to approximately 35°C. Upon cooling, the aliphatic alcohol and surfactant crystallize, forming a crystalline gel network. Table 1 shows the components and their respective amounts of exemplary gel network compositions.

[0181] [Table 1]

[0182] Water-miscible solvent Useful carriers in hair care compositions include water, as well as aqueous solutions of lower alkyl alcohols, polyhydric alcohols, ketones having 3 to 4 carbon atoms, C1 to C6 esters of C1 to C6 alcohols, sulfoxides, amides, carbonate esters, ethoxylated and propoxylated C1 to C10 alcohols, lactones, pyrrolidones, and mixtures thereof. Non-limiting examples of lower alkyl alcohols are monohydric alcohols having 1 to 6 carbon atoms, such as ethanol and isopropanol. Non-limiting examples of polyhydric alcohols useful herein include propylene glycol, dipropylene glycol, butylene glycol, hexylene glycol, glycerin, propanediol, and mixtures thereof.

[0183] The hair care composition may contain a hydrotrope / viscosity modifier which is an alkali metal or ammonium salt of a lower alkylbenzene sulfonic acid, such as sodium xylene sulfonate, sodium cumene sulfonate, or sodium toluene sulfonate.

[0184] Hair care compositions may contain silicone / PEG-8 silicone / PEG-9 silicone / PEG-n silicone / silicone ether (where n is another integer), and non-limiting examples include PEG-8 dimethicone A208)MW855 and PEG-8 dimethicone D208MW2706.

[0185] Soluble anti-dandruff agent The anti-dandruff agent may be one material or a mixture selected from the group consisting of azoles such as crimbazole, ketoconazole, itraconazole, econazole, and erbiol; kerolytic agents such as hydroxypyridones such as octopirox (piroctone olamine), cyclopirox, rilopirox, and MEA-hydroxyoctyloxypyridinone, salicylic acid, and other hydroxy acids; strobilurins such as azoxystrobin, and metal chelating agents such as 1,10-phenanthroline.

[0186] In the present invention, the azole antimicrobial agent may be an imidazole selected from the group consisting of benzimidazole, benzothiazole, bifonazole, butaconazole nitrate, crimbazole, clotrimazole, croconazole, everconazole, econazole, erbiol, fenticonazole, fluconazole, fluthymazole, isoconazole, ketoconazole, lanoconazole, metronidazole, miconazole, neticonazole, omoconazole, oxiconazole nitrate, sertaconazole, sarconazole nitrate, thioconazole, thiazole, and mixtures thereof, or the azole antimicrobial agent may be a triazole selected from the group consisting of terconazole, itraconazole, and mixtures thereof. The azole antimicrobial agent may also be ketoconazole. Furthermore, the sole antimicrobial agent may be ketoconazole.

[0187] Soluble anti-dandruff agents may be present in amounts of approximately 0.01% to 10%, approximately 0.02% to 8%, and approximately 0.05% to 5%. Soluble anti-dandruff agents may be surfactant-soluble and therefore may be surfactant-soluble anti-dandruff agents.

[0188] Scalp health supplement In the present invention, one or more scalp health agents may be added to provide effects on the scalp in addition to the antifungal / antidandruff effect provided by surfactant-soluble antidandruff agents. These materials are diverse and provide a wide range of effects, including humidification, barrier improvement, antifungal, antibacterial, and antioxidant, anti-itch, and sensory stimulation. Non-limiting examples of further antidandruff agents include polyvalent metal salts of pyrithione, such as zinc pyrithione (ZPT), copper pyrithione, sulfur, or selenium sulfide. Such scalp health agents include vitamins E and F, salicylic acid, niacinamide, caffeine, panthenol, zinc oxide, zinc carbonate, basic zinc carbonate, glycol, glycolic acid, PCA, PEG, erythritol, glycerin, triclosan, lactate, hyaluronic acid, allantoin, and other ureas, betaine, sorbitol, glutamate, xylitol, menthol, menthyl lactate, isocyclomon, benzyl alcohol, and compounds containing the following structures:

[0189] [ka] (R1 is selected from H, alkyl, aminoalkyl, and alkoxy, Q=H2, O, -OR1, -N(R1)2, -OPO(OR1) x , -PO(OR1) x , -P(OR1) x (In the formula, x=1~2), V = NR1, O, -OPO(OR1) x , -PO(OR1) x , -P(OR1) x (In the formula, x=1~2), W=H2, O, When n=0, X and Y are selected independently from H, aryl, and naphthyl. If n≧1, X and Y are aliphatic CH2 or aromatic CH, and Z is selected from aliphatic CH2, aromatic CH, or heteroatoms. A = lower alkoxy, lower alkylthio, aryl, substituted aryl, or condensed aryl. * (At the position of the mark, the stereochemistry is variable.) This also includes, but is not limited to, natural extracts / oils containing peppermint, spearmint, argan, jojoba, and aloe.

[0190] Scalp health products can be present in concentrations of approximately 0.01% to 10%, 0.05% to 9%, 0.1% to 8%, and 0.25% to 6%.

[0191] Optional ingredients In the present invention, the hair care composition may further contain one or more optional components, such as beneficial agents. Suitable beneficial agents include, but are not limited to, conditioning agents, cationic polymers, silicone emulsions, anti-dandruff agents, gel networks, chelating agents, and natural oils such as sunflower oil or castor oil. Further suitable optional components include, but are not limited to, fragrances, fragrance microcapsules, colorants, particles, antibacterial agents, defoaming agents (foam busters), antistatic agents, rheological modifiers and thickeners, suspension materials and structuring agents, pH adjusters and buffers, preservatives, pearlescent agents, solvents, diluents, antioxidants, vitamins, and combinations thereof. The composition may contain about 0.5% to about 7% fragrance.

[0192] Such optional components must be physically and chemically compatible with the components of the composition and must not otherwise excessively impair the stability, aesthetics, or performance of the product. The CTFA Cosmetic Ingredient Handbook, 10th edition (published by the Cosmetic, Toiletry, and Fragrance Association, Inc. (Washington, DC)) (2004) (hereinafter referred to as "CTFA") describes a variety of non-limiting materials that may be added to the compositions herein.

[0193] 1. Conditioning agent The conditioning agent of the hair care composition may be a silicone conditioning agent. The silicone conditioning agent may include volatile silicones, non-volatile silicones, or a combination thereof. The concentration of the silicone conditioning agent is typically in the range of about 0.01% to about 10% by weight, about 0.1% to about 8% by weight, about 0.1% to about 5% by weight, and / or about 0.2% to about 3% by weight of the composition. Non-limiting examples of suitable silicone conditioning agents and optional suspending agents for silicones are described in U.S. Reissue Patent No. 34,584, U.S. Patent No. 5,104,646, and U.S. Patent No. 5,106,609, which are incorporated herein by reference.

[0194] Silicone conditioning agents for use in the compositions of the present invention may have viscosities of about 20 to about 2,000,000 centistokes ("csk"), about 1,000 to about 1,800,000 csk, about 10,000 to about 1,500,000 csk, and / or about 20,000 to about 1,500,000 csk when measured at 25°C.

[0195] Dispersed silicone conditioning agent particles typically have a volume-average particle size ranging from about 0.01 micrometers to about 60 micrometers. When smaller particles are applied to hair, the volume-average particle size typically ranges from about 0.01 micrometers to about 4 micrometers, about 0.01 micrometers to about 2 micrometers, and about 0.01 micrometers to about 0.5 micrometers.

[0196] Further information on silicones, including sections on silicone fluids, rubbers, and resins, as well as the manufacture of silicones, can be found in the Encyclopedia of Polymer Science and Engineering, vol. 15, 2d ed., pp. 204-308, John Wiley & Sons, Inc. (1989), which is incorporated herein by reference.

[0197] Suitable silicone emulsions for use in the present invention include, but are not limited to, emulsions of insoluble polysiloxanes. These can be prepared by emulsion polymerization as described in U.S. Patent No. 6,316,541, or No. 4,476,282, or U.S. Patent Application Publication No. 2007 / 0276087, or they can be emulsified after polymerization is complete by various emulsification methods as described in U.S. Patent No. 9,255,184(B2), or No. 7,683,119, or Emulsions and Emulsion Stability, edited by Johan Sjoblom, CRC Press, 2005. Based on these references, a non-limiting list of suitable emulsifiers and emulsifier blends can be considered, based on the functionality of the silicone used, the emulsification method, and the desired emulsion particle size. Therefore, suitable insoluble polysiloxanes include polysiloxanes such as α,ω-hydroxy-terminated polysiloxanes or α,ω-alkoxy-terminated polysiloxanes having an internal phase viscosity of about 5 csk to about 500,000 csk. For example, insoluble polysiloxanes may have internal phase viscosities of less than 400,000 csk, less than 200,000 csk, or about 10,000 csk to about 180,000 csk. Insoluble polysiloxanes may have an average particle size in the range of about 10 nm to about 10 micrometers. The average particle size may be, for example, in the range of about 15 nm to about 5 micrometers, about 20 nm to about 1 micrometer, about 25 nm to about 550 nm, or about 1 to 10 micrometers. The concentration of dispersed silicone in the emulsion may be in the range of about 5 to 90 weight percent, or 20 to 85 weight percent, or 30 to 80 weight percent of the emulsion composition.

[0198] The average molecular weight of the insoluble polysiloxane, the internal phase viscosity of the insoluble polysiloxane, the viscosity of the silicone emulsion, and the particle size containing the insoluble polysiloxane are measured by methods widely used by those skilled in the art, such as the method disclosed in Smith, AL The Analytical Chemistry of Silicones, John Wiley & Sons, Inc.: New York, 1991. For example, the viscosity of the silicone emulsion can be measured at 30°C using a Brookfield viscometer with a spindle 6 at 2.5 rpm. The silicone emulsion may further contain additional emulsifiers, along with anionic surfactants.

[0199] Other types of silicones suitable for use in the compositions of the present invention include, but are not limited to, i) silicone fluids (including, but not limited to, silicone oils) which are fluid substances having a viscosity of less than about 1,000,000 csk when measured at 25°C; ii) aminosilicones containing at least one primary, secondary, or tertiary amine; iii) cationic silicones containing at least one quaternary ammonium functional group; iv) silicone rubbers (including materials having a viscosity of 1,000,000 csk or more when measured at 25°C); v) silicone resins including highly crosslinked polymer siloxanes; vi) high refractive index silicones having a refractive index of at least 1.46; and vii) mixtures thereof.

[0200] The conditioning agent of the hair care composition of the present invention may further contain at least one organic conditioning material, such as an oil or wax, either alone or in combination with other conditioning agents such as the silicones described above. The organic material may be a nonpolymer, oligomer, or polymer. It may be in the form of an oil or wax and may be added directly to the formulation or in a pre-emulsified form. Some non-limiting examples of organic conditioning materials include, but are not limited to, polyethylene glycol and polypropylene glycol having a molecular weight of up to about 2,000,000, such as i) hydrocarbon oils, ii) polyolefins, iii) aliphatic esters, iv) fluorinated conditioning compounds, v) aliphatic alcohols, vi) alkyl glucosides and alkyl glucoside derivatives, vii) quaternary ammonium compounds, viiii) polyethylene glycol and polypropylene glycol having a molecular weight of up to about 2,000,000, such as those with CTFA names PEG-200, PEG-400, PEG-600, PEG-1000, PEG-2M, PEG-7M, PEG-14M, PEG-45M, and mixtures thereof.

[0201] 2. Emulsifier Various anionic and nonionic emulsifiers can be used in the hair care compositions of the present invention. Anionic and nonionic emulsifiers can be essentially monomers or polymers. Examples of monomers include, but are not limited to, alkyl ethoxylates, alkyl sulfates, soaps, and fatty acid esters, and their derivatives. Examples of polymers include, but are not limited to, polyacrylates, polyethylene glycols, and block copolymers, and their derivatives. Naturally occurring emulsifiers such as lanolin, lecithin, and lignin, and their derivatives, are also non-limiting examples of useful emulsifiers.

[0202] 3. Chelating agents Hair care compositions may further contain chelating agents. Suitable chelating agents are those described in AE Martell & R M Smith, Critical Stability Constants, Vol. 1, Plenum Press, New York & London (1974) and AE Martell & R D Hancock, Metal Complexes in Aqueous Solution, Plenum Press, New York & London (1996), both of which are incorporated herein by reference. With respect to chelating agents, the term “salts and derivatives thereof” means salts and derivatives that contain the same functional structure (e.g., the same chemical backbone) as the referenced chelating agent and have similar or better chelating properties. This term includes alkali metals, alkaline earth metals, ammonium, substituted ammonium salts (i.e., monoethanolammonium, diethanolammonium, triethanolammonium) salts, esters of chelating agents having an acidic moiety, and mixtures thereof, in particular all sodium, potassium, or ammonium salts. The term “derivative” also includes “chelating surfactant” compounds, such as those exemplified in U.S. Patent No. 5,284,972, and large molecules containing one or more chelating groups having the same functional structure as the parent chelating agent, such as polymer EDDS (ethylenediamine disuccinic acid) disclosed in U.S. Patent No. 5,747,440.

[0203] Chelating agents can be incorporated into the compositions described herein in amounts ranging from 0.001% to 10.0% by weight, or about 0.01% to 2.0%, of the total composition.

[0204] Examples of non-restrictive chelating agents include carboxylic acids, aminocarboxylic acids, such as aminosides, phosphoric acid, phosphonic acid, polyphosphonic acid, polyethyleneimine, polyfunctionally substituted aromatics, their derivatives, and salts.

[0205] Examples of non-limiting chelating agents include the following materials and their salts: ethylenediaminetetraacetic acid (EDTA), ethylenediaminetriacetic acid, ethylenediamine-N,N'-disuccinic acid (EDDS), ethylenediamine-N,N'-diglutaric acid (EDDG), salicylic acid, aspartic acid, glutamic acid, glycine, malonic acid, histidine, diethylenetriaminepentaacetate (DTPA), N-hydroxyethylethylenediamine triacetate, nitrilotriacetate, ethylenediaminetetrapropionate, and tri Ethylenetetraamine hexaacetate, ethanol diglycine, propylenediaminetetraacetic acid (PDTA), methylglycine diacetic acid (MODA), diethylenetriamine pentaacetic acid, methylglycine diacetic acid (MGDA), N-acyl-N,N',N'-ethylenediamine triacetic acid, nitrilotriacetic acid, ethylenediamine diglutaric acid (EDGA), 2-hydroxypropylenediamine disuccinate (HPDS), glycinamide-N,N'-disuccinate (GADS), 2-Hydroxypropylenediamine-N-N'-disuccinic acid (HPDDS), N-2-hydroxyethyl-N,N-diacetic acid, glyceryl iminodiacetic acid, iminodiacetic acid-N-2-hydroxypropyl sulfonic acid, aspartate N-carboxymethyl-N-2-hydroxypropyl-3-sulfonic acid, alanine-N,N'-diacetic acid, aspartate-N,N'-diacetic acid, aspartate N-monoacetic acid, iminodisuccinic acid, diamine-N,N'-dipolyacid, monoa Mido-N,N'-dipolyacid, diaminoalkyl di(sulfosuccinate) (DDS), ethylenediamine-N-N'-bis(ortho-hydroxyphenylacetic acid)), N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid, ethylenediaminetetrapropionate, triethylenetetraamine hexaacetate, diethylenetriamine pentaacetate, dipicolinic acid, ethylenedisysteic acid (EDC), ethylenediamine-N,N'-bis(2-hydroxyphenylacetic acid) (EDDHA), glutamic acid diacetic acid (GLDA), hexaaminocarboxylate (HBED), polyethyleneimine, 1-hydroxydiphosphonate, aminotri(methylenephosphonic acid) (ATMP), nitrilotrimethylenephosphonate (NTP), ethylenediaminetetramethylenephosphonate, diethylenetriaminepentamethylenephosphonate (DTPMP), ethane-1-hydroxydiphosphonate (HEDP), 2-phosphonobutane-1,2,4-tricarboxylic acid, polyphosphate (polvphosphoric acid), sodium tripolyphosphate, tetrasodium diphosphate, hexametaphosphate, sodium metaphosphate, phosphonic acids and derivatives, aminoalkylene-poly(alkylenephosphonic acid), aminotri(1-ethylphosphonic acid), ethylenediaminetetra(1-ethylphosphonic acid), aminotri(1-propylphosphonic acid), Aminotri(isopropylphosphonic acid), ethylenediaminetetra(methylenephosphonic acid) (EDTMP), 1,2-dihydroxy-3,5-disulfobenzene.

[0206] Water-based carrier The hair care composition may be in the form of a pourable liquid (under ambient conditions). Thus, such a composition typically contains a carrier, which is present in a concentration of about 40% to about 85% by weight, alternatively about 45% to about 80% by weight, or alternatively about 50% to about 75% by weight of the hair care composition. The carrier may include water, or a miscible mixture of water and an organic solvent, and in one embodiment, may include water with a minimal amount of organic solvent or without a significant concentration of organic solvent, unless incidentally incorporated into the composition as a trace component of other essential or optional components.

[0207] Carriers that may be useful in the hair care composition of the present invention include water, and aqueous solutions of lower alkyl alcohols and polyhydric alcohols. Lower alkyl alcohols useful herein are monohydric alcohols having 1 to 6 carbon atoms, in one embodiment, ethanol and isopropanol. Exemplary polyhydric alcohols useful herein include propylene glycol, hexylene glycol, glycerin, and propanediol.

[0208] G. Product form The hair care composition of the present invention may be present in typical hair care formulations. This composition may be in the form of a solution, dispersion, emulsion, powder, talc, capsule, sphere, sponge, solid dosage form, foam, and other delivery mechanisms. The composition of the present invention may be in the form of leave-on hair products such as hair tonics, treatments and styling products, rinse-off hair products such as shampoos and personal cleansing products, and treatment products, as well as any other form that can be applied to the hair.

[0209] H. Applicator In this invention, the hair care composition may be dispensed from an applicator for direct dispensing onto the scalp. Dispensing directly onto the scalp via a targeted delivery applicator allows for direct application of the undiluted cleanser to areas where cleansing is particularly needed. This also minimizes the risk of the cleansing solution getting into the eyes.

[0210] The applicator is attached to, or can be attached to, a bottle containing a cleansing hair care composition. The applicator may consist of a base that holds or extends to one or more comb teeth. The comb teeth may have openings that are located at the tip, the base, or at any point between the tip and the base. These openings allow the product to be dispensed directly from the bottle onto the hair and / or scalp.

[0211] Alternatively, the applicator may consist of brush-like bristles attached to or extending from the base. In this case, the product is dispensed from the base, and the bristles allow for distribution of the product through a combing or brushing motion.

[0212] The design and materials of the applicator and comb teeth can also be optimized to allow for scalp massage. In this case, it is beneficial for the shape of the comb teeth or bristles at the tip to be more rounded, similar to the rollerball applicators used for eye cream. The material may also be smoother and softer, for example, a metallic or metallic finish, or a "rubber-like material."

[0213] Materials and methods Antibacterial agent efficacy test The following methods are based on the United States Pharmacopeia. <51> This is based on the following: A bacterial pool consisting of equal parts of K. pneumoniae, E. gergoviae, S. marcescens, S. aureus, P. aeruginosa, E. coli, and B. cepacia is inoculated into a shampoo composition and a physiological saline control, and the target bioburden is 5.0-7.0 log. 10 The concentration is set to cfu / mL. After incubation at room temperature for 2 and 7 days, the inoculated composition and the physiological saline control are diluted with modified lecithin broth (Becton Dickinson, Cat. No. 263010) + polysorbate 80. The solution is injected three times onto tryptosoy agar (Becton Dickinson, Cat. No. 255320) along with lecithin and polysorbate 80, and the colony-forming units (cfu) are counted.

[0214] Calculation of logarithmic decrease As shown in the sample calculation below, the average microbial cfu per mL is calculated by averaging the data from the injection plates and multiplying by the dilution factor. The logarithmic decrease of microorganisms is calculated by dividing the cfu per mL of the saline control over a period of time (2 or 7 days) by the cfu per mL of the composition, and taking the logarithm of the quotient. 10This is calculated by taking [a specific method]. The resulting value is the logarithmic decrease of the composition relative to the physiological saline control. Based on the variability of the antimicrobial efficacy test, a difference of 0.5 logarithmic decrease between compositions is considered statistically significant.

[0215] Alternatively, another conventional method for calculating the logarithmic decline of a composition involves diluting the inoculum at inoculation, properly incubating it in growth agar, and then counting the colonies. The resulting cfu per 1 mL of inoculum is used in place of the saline control in the numerator of the formula for calculating the logarithmic decline.

[0216] Net change in logarithmic decrease calculation The net change in the logarithmic decrease of microorganisms can be calculated by subtracting the logarithmic decrease of the unpreserved control from the logarithmic decrease of the shampoo composition.

[0217] Sample calculation:

[0218] [Table 2] Average cfu / mL = Average cfu × Dilution factor Average cfu / mL of the composition = 10.3 × 100 Average cfu / mL of the composition = 1.03 × 10³

[0219]

number

[0220] [Table 3] Net change due to logarithmic decrease = logarithmic decrease of composition - logarithmic decrease of unpreserved control Net change due to logarithmic decrease = 3.2 - (-0.2) Net change due to logarithmic decrease = 3.4

[0221] Preparation of shampoo composition The shampoo composition is prepared by adding surfactants, anti-dandruff agents, fragrances, viscosity modifiers, cationic polymers, preservatives, conditioning agents, and the remainder of water with thorough stirring to ensure a homogeneous mixture. The mixture may be heated to 50-75°C to accelerate the solubilization of the soluble agents and the hydration of the cationic polymers, and then cooled. The pH of the product may be adjusted as needed to provide the shampoo composition of the present invention suitable for application to human hair and scalp, and may vary from about 6 or less, or about 4.5 to about 6, or greater than 4.5 to about 6, or about 4 to 6, or about 4 to 5.8, or about 4.5 to 5.8, or greater than 4.5 to 5.8, or 4.5 to 5.5, or greater than 4.5 to 5.5, based on the selection of specific cleansing surfactants and / or other components.

[0222] Non-limiting examples The shampoo compositions shown in the following examples are prepared by conventional formulation and mixing methods. All quantities exemplified are listed as weight percentages of activity, excluding diluents, preservatives, coloring solutions, pictorial components, plant-based trace materials, etc., unless otherwise specified. Unless otherwise specified, all percentages are based on weight.

[0223] [Table 4]

[0224] Discussion of the results for Examples 1-3 On day 7, the untreated control (Example 1) showed a negative logarithmic decrease in bacteria, indicating bacterial growth. Based on the variability of the antimicrobial efficacy test as described in the method disclosure, a difference of 0.5 logarithmic decrease between compositions is considered statistically significant.

[0225] Examples 2 and 3 are representative compositions of the present invention. Compared to the untreated control (Example 1), Example 2 showed a net change in the logarithmic reduction of bacteria of 1.0 on day 2 and 3.1 on day 7. Compared to the untreated control (Example 1), Example 3 showed a net change in the logarithmic reduction of bacteria of 1.9 on day 2 and 5.5 on day 7. These net changes in logarithmic reduction indicate that the antibacterial properties of the representative compositions were significantly improved compared to the untreated control, which is surprising considering that the sodium salicylate concentrations in Examples 2 and 3 were very low, at 0.04% and 0.07%, respectively.

[0226] [Table 5]

[0227] Discussion of the results for Examples 4-6 At both the 2nd and 7th day, the unpreserved control (Example 4) showed a negative logarithmic decrease in bacteria, indicating bacterial growth and demonstrating that this preservative-free control composition does not impart antimicrobial properties. Based on the variability of the antimicrobial efficacy test as described in the Method Disclosure, a difference of 0.5 logarithmic decrease between compositions is considered statistically significant.

[0228] Examples 5 and 6 are representative compositions of the present invention. Compared to the untreated control (Example 4), Example 5 showed a net change in the logarithmic reduction of bacteria of 1.0 on day 2 and 1.7 on day 7. Compared to the untreated control (Example 4), Example 6 showed a net change in the logarithmic reduction of bacteria of 1.2 on day 2 and 2.2 on day 7. These net changes in the logarithmic reduction indicate that the antimicrobial properties of the representative compositions were significantly improved compared to the untreated control, which is remarkable considering that the sodium salicylate concentrations in Examples 5 and 6 were very low, at 0.04% and 0.07%, respectively.

[0229] [Table 6]

[0230] Discussion of Results for Examples 7 - 9 At both the second and seventh day, in the non - preserved control (Example 7), the bacterial logarithmic decrease was negative, indicating bacterial growth, showing that this control composition without preservatives does not confer antibacterial properties. Based on the variability of the antibacterial effect test, a difference in logarithmic decrease of 0.5 between compositions is considered a significant difference.

[0231] Examples 8 and 9 are representative compositions of the present invention. When comparing Example 8 with the non - preserved control (Example 7), the net change in bacterial logarithmic decrease was 1.8 at the second day and 4.7 at the seventh day. When comparing Example 9 with the non - preserved control (Example 7), the net change in bacterial logarithmic decrease was 1.9 at the second day and 7.6 at the seventh day. These net changes in logarithmic decrease indicate that the antibacterial properties of the representative compositions were significantly improved compared to the non - preserved control, which is surprising considering that the sodium salicylate concentrations in Examples 8 and 9 were very low at 0.04% and 0.07% respectively.

[0232] [Table 7]

[0233] Discussion of Results for Examples 10 - 12 At both the second and seventh day, in the non - preserved control (Example 10), the bacterial logarithmic decrease was negative, indicating bacterial growth, showing that this control composition without preservatives does not confer antibacterial properties. Based on the variability of the antibacterial effect test, a difference in logarithmic decrease of 0.5 between compositions is considered a significant difference.

[0234] Examples 11 and 12 are representative compositions of the present invention. Compared to the unpreserved control (Example 10), Example 11 showed a net change in the logarithmic reduction of bacteria of 1.9 on day 2 and 3.1 on day 7. Compared to the unpreserved control (Example 10), Example 12 showed a net change in the logarithmic reduction of bacteria of 2.0 on day 2 and 5.6 on day 7. These net changes in logarithmic reduction indicate that the antimicrobial properties of the representative compositions were significantly improved compared to the unpreserved control, which is remarkable considering that the sodium salicylate concentrations in Examples 11 and 12 were very low, at 0.04% and 0.07%, respectively. These examples also demonstrate that the illustrated antimicrobial effect is independent of the surfactant concentration.

[0235] The results of the present invention show a hair care composition that provides a net change in bacterial logarithm reduction of 0.5 or more compared to an unpreserved control. The results show that the hair care composition provides a net change in bacterial logarithm reduction of 0.5 or more compared to an unpreserved control at day 7. The results show that the hair care composition provides a net change in bacterial logarithm reduction of 0.5 or more compared to an unpreserved control at day 2. The results show that the hair care composition provides a net change in bacterial logarithm reduction of 0.5 or more compared to an unpreserved control at both day 2 and day 7.

[0236] The dimensions and values ​​disclosed herein should not be understood as being strictly limited to the exact numerical values ​​listed. Instead, unless otherwise indicated, each such dimension is intended to mean both the listed value and the functionally equivalent range encompassing that value. For example, a dimension disclosed as "40 mm" is intended to mean "approximately 40 mm."

[0237] All documents referenced herein, including any patents or patent applications that are cross-referenced or related, and any patent applications or patents on which this application claims priority or benefit thereof, are incorporated herein by reference in their entirety unless otherwise explicitly stated to be excluded or limited. No reference of any document shall be deemed prior art to any invention disclosed or claimed herein, nor shall it be deemed to teach, suggest or disclose any such invention, either alone or in combination with any other reference(s). Furthermore, if any meaning or definition of a term in this document conflicts with any meaning or definition of the same term in any document incorporated by reference, the meaning or definition given to the term in this document shall prevail.

[0238] While specific embodiments of the present invention have been illustrated and described, it will be apparent to those skilled in the art that various other changes and modifications can be made without departing from the spirit and scope of the invention. Therefore, it is intended that all such changes and modifications within the scope of the invention be covered in the appended claims.

Claims

1. A hair care composition, a. 8-17% of one or more anionic surfactants, b. 0.04-0.15% salicylate or salicylic acid, c. Containing 0.04 to 0.15% benzoate or benzoic acid, d. A hair care composition in which the weight ratio of salicylate or salicylic acid to benzoate or benzoic acid is 1:0.8 to 2:

1.

2. The hair care composition according to claim 1, wherein the salicylate or salicylic acid is present in an amount of 0.07 to 0.15%.

3. The hair care composition according to claim 1 or 2, wherein the salicylate comprises sodium salicylate.

4. A hair care composition according to any one of claims 1 to 3, comprising 0.07 to 0.15% of a benzoate or benzoic acid.

5. The hair care composition according to any one of claims 1 to 4, wherein the composition provides a net change of 0.5 or more in bacterial logarithm reduction compared to an unpreserved control.

6. The hair care composition according to any one of claims 1 to 5, wherein the composition provides a net change of 0.5 or more in bacterial logarithm reduction compared to an unpreserved control at the 7th day.

7. The hair care composition according to any one of claims 1 to 6, wherein the composition provides a net change of 0.5 or more in bacterial logarithm reduction compared to an unpreserved control at the second day.

8. The hair care composition according to any one of claims 1 to 7, wherein the composition provides a net change of 0.5 or more in bacterial logarithm reduction compared to an unpreserved control at the time of the second day and the seventh day.

9. The anionic surfactant is an anionic surfactant selected from the group consisting of anionic alkyl sulfates and alkyl ether sulfates having linear or branched alkyl chains, and mixtures thereof, and is an anionic surfactant selected from the group consisting of sodium lauryl sulfate, sodium laureth-n sulfate with n = 0.5 to 3.5, sodium C10-15 alkyl sulfates whose alkyl chain may be linear or branched, sodium C10-15 pareth-n sulfates whose n = 0.5 to 3.5 and whose alkyl chain may be linear or branched, sodium decyl sulfate, sodium deceth-n sulfate with n = 0.5 to 3.5, sodium undecyl sulfate, sodium undeceth-n sulfate with n = 0.5 to 3.5, sodium tridecyl sulfate, sodium trideceth-n sulfate with n = 0.5 to 3.5, and the anionic surfactant is, a.R 1 O(CH 2 CHR 3 O) y SO 3 M、 b. CH 3 (CH 2 ) z CHR 2 CH 2 O(CH 2 CHR 3 O) y SO 3 M, and c. Selected from the group consisting of these mixtures, In the formula, R 1 CH 3 (CH 2 ) 11 Represents R 2 H, or z and R 2 R represents a hydrocarbon group containing 1 to 4 carbon atoms such that the total number of carbon atoms in the group is 8. 3 is H, or CH 3 The hair care composition according to any one of claims 1 to 8, wherein y is between 0 and 7, and when y is not zero (0), the average value of y is 1, and M is a monovalent or divalent positively charged cation.

10. The hair care composition according to claim 9, wherein the anionic surfactant is present in an amount of 8% to 16%.

11. The hair care composition according to any one of claims 9, wherein the anionic surfactant comprises 0 to 3% by weight of a sulfate-based surfactant.

12. The hair care composition according to any one of claims 1 to 11, wherein the composition further comprises 0.01% to 10% of a soluble anti-dandruff agent, the soluble anti-dandruff agent being selected from the group consisting of hydroxylpyridone, azole, piroctone olamine, crimbazole, and mixtures thereof.

13. The product further contains one or more scalp health agents in an amount of 0.01% to 10%, wherein the one or more scalp health agents include sulfur, polyvalent metal salts of pyrithione, zinc pyrithione, vitamins E and F, niacinamide, caffeine, panthenol, zinc oxide, zinc carbonate, basic zinc carbonate, glycol, glycolic acid, pyrrolidone carboxylic acid (PCA), polyethylene glycol (PEG), erythritol, glycerin, triclosan, lactate, hyaluronic acid, allantoin and other ureas, betaine, sorbitol, glutamate, xylitol, menthol, menthyl lactate, isocyclomone, benzyl alcohol, and compounds containing the following structures: 【Chemistry 1】 (R 1 It is selected from H, alkyl, aminoalkyl, and alkoxy. Q = H 2 , O, -OR 1 , -N(R 1 ), 2 , -OPO(OR 1 ), x , -PO(OR 1 ), x , -P(OR 1 ), x (where x = 1 to 2), V = NR 1 , O, -OPO(OR 1 ) x , -PO(OR 1 ) x , -P(OR 1 ) x (where x = 1 to 2), W=H 2 、O、 When n=0, X and Y are selected independently from H, aryl, and naphthyl. When n ≥ 1, X and Y are aliphatic CH 2 Alternatively, it is an aromatic CH, and Z is an aliphatic CH. 2 Selected from aromatic CH or heteroatoms, A = lower alkoxy, lower alkylthio, aryl, substituted aryl, or condensed aryl. * (At the position of the mark, the stereochemistry is variable.) The hair care composition according to any one of claims 1 to 12, further comprising natural extracts / oils selected from peppermint, spearmint, argan, jojoba, and aloe.

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