Novel fluorescent compounds for labeling tumor tissue
Novel fluorescent compounds with tumor-specific affinity and prolonged persistence address the limitations of existing markers by ensuring complete tumor localization and improved surgical guidance.
JP7864694B2Active Publication Date: 2026-05-25プロイメージング
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Patent Information
- Authority / Receiving Office
- JP · JP
- Patent Type
- Patents
- Current Assignee / Owner
- プロイメージング
- Filing Date
- 2021-05-12
- Publication Date
- 2026-05-25
AI Technical Summary
Technical Problem
Existing fluorescent markers have limited fluorescence persistence, require binding to targeting molecules, and fail to provide sufficient specificity and duration for tumor tissue labeling, leading to incomplete tumor localization and visualization during surgery.
Method used
Development of novel fluorescent compounds with specific affinity for tumor tissue, allowing direct use without prior binding, and exhibiting prolonged persistence in tumor tissue up to several days, enhancing visualization and differentiation from healthy tissue.
Benefits of technology
The compounds provide improved tumor tissue labeling and visualization, enabling more effective surgical interventions by maintaining a high signal-to-noise ratio and clear tumor boundaries for extended periods.
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Abstract
The subject of the present invention is a novel fluorescent compound that can be used to label tumor tissue, a method for preparing it, and its use as a monitoring or diagnostic or auxiliary tool in relation to cancer surgery.
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