Syringe-type microneedle

Abstract

The present invention relates to a syringe-type microneedle, which comprises a housing having an air discharge hole formed on its outer periphery that is connected to an internal air retention space, and a press-in block for opening and closing the air discharge hole in the housing, a needle part formed on the bottom surface of the press-in block, a pressurizing part formed in the air retention space of the housing, the lower end of the housing sealed with a protective film, and when the pressurizing part is pressurized and the press-in block moves downward due to the air pressure in the air retention space, the needle part formed in the press-in block passes through the bottom of the housing and penetrates the skin to inject a drug, and at the same time, the air in the air retention space is discharged to the outside by opening the air discharge hole in the press-in block, and the press-in of the press-in block is released, guiding the point of removal of the needle part that has penetrated the skin. According to the present invention, after the needle part penetrates into the skin layer by the simple action of pressing the press-in block against the pressure part, the press-in force is automatically released at a predetermined time point, and the release of the press-in force of the press-in block allows the practitioner to easily predict the time point when the needle part will be released and separated. With the guide of the time point when the needle part will be released and separated, even inexperienced persons can easily use it, and a uniform amount of medicine can be infused into the patient, so that the same therapeutic effect can be given to the patients. In particular, after the medicine in the needle part is infused into the skin layer, the needle part is quickly removed, so there is no risk of the needle part remaining in the skin layer excessively.

Description

Technical Field

[0001] The present invention relates to a micro needle, and more particularly, to a syringe-type micro needle in which a press-in block is pushed by a sealed pressure in an air retention space of a housing to penetrate a needle portion into the skin, and when the air discharge hole is opened by the movement of the press-in block, the air in the air retention space is discharged through the air discharge hole while the press-in of the press-in block is released.

Background Art

[0002] Generally, in order to solve problems such as pain associated with injection sites, local damage to the skin, bleeding, and disease infection at the injection site, which are problems of methods of administering drugs using injection needles (needles) recently, technologies related to various microstructures including micro needles (ultra-fine needles, microneedles) have been proposed.

[0003] The micro structure is a patch-type painless injection that injects a drug without pain with a micro needle as a structure for efficiently transmitting a drug transmitted through the skin.

[0004] Since such a micro structure has to come into contact with the skin surface of the human body (particularly, the face area) and have a use time of a certain period (for example, 30 minutes to 8 hours or more), recently, a patch-type micro needle patch that adheres to the skin is often used to safely adhere and maintain it on the skin.

[0005] Patent Document 1 (KR10-2015-0122367A) describes a conventional depth-adjustable injection needle using microneedles, and referring to this, the device consists of an injection needle hub which is cylindrical in shape and has multiple microneedles formed on its front surface, a rotating body which is hollow with open front and rear and has female threads formed on its inner circumference to allow insertion of the injection needle hub, an injection needle cap which is hollow with an open rear end and has male threads formed on its outer circumference that connect to the female threads and has through holes corresponding to the microneedles on its front surface, and a protective cap which covers the front surface of the injection needle cap and blocks the supply of contaminated air to the through holes.

[0006] Here, the injection needle hub consists of a tip that secures the microneedle and forms a connecting passage that guides the drug to move into the microneedle, and a rear end that extends from the rear end of the tip and forms an insertion home that communicates with the connecting passage and allows the syringe cylinder to be connected.

[0007] At this time, when the injection needle cap is rotated in a predetermined direction so that the male thread rotates along the female thread of the rotating body, the rotating body rotates up or down or up relative to the injection needle cap, adjusting its height. In this state, when pressure is applied so that the injection needle hub moves towards the injection needle cap through the rotating body, the microneedle is exposed through the through-hole and penetrates the skin.

[0008] In other words, by adjusting the height of the rotating body relative to the injection needle cap, the length of the microneedle exposed through the through-hole of the injection needle cap is adjusted, thereby changing the length of the microneedle that penetrates the skin.

[0009] However, as described in Patent Document 1 (KR10-2015-0122367A) above, the practitioner must directly judge and take measures for the time the microneedles exposed on the injection needle cap penetrate and remain in the skin. Depending on the practitioner's medical skill, there may be deviations in the time it takes to deliver the drug to the skin layer while ensuring the microneedles remain in the skin, making it difficult to deliver a uniform amount of drug to the patient. Furthermore, for inexperienced practitioners, it is difficult to predict the time it takes for the drug from the microneedles to penetrate the skin, resulting in the inconvenience of having to leave the microneedles in the skin for a long time. In this case, the microneedles remaining in the skin for an excessive time may cause skin damage or necrosis of skin tissue. Moreover, during the process of pressing the injection needle hub into the skin, the front surface of the injection needle cap, which is in close contact with the skin, slides across the skin layer, causing the microneedles that have penetrated the skin to move within the skin layer. This movement of microneedles within the skin layer may cause the patient to complain of pain, thus reducing the reliability of the product. [Overview of the Initiative] [Problems that the invention aims to solve]

[0010] The present invention aims to solve the aforementioned problems, and the objective of the present invention is to provide a syringe-type microneedle comprising a housing having an air discharge hole formed on its outer surface that communicates with an internal air retention space, a press-fitting block that opens and closes the air discharge hole inside the housing, a needle portion formed on the bottom surface of the press-fitting block, a pressurizing portion formed in the air retention space of the housing, the lower end of the housing sealed with a protective film, and when this protective film is removed and the pressurizing portion is pressurized so that the press-fitting block moves downward due to the air pressure in the air retention space, the needle portion formed on the press-fitting block is exposed at the bottom of the housing and penetrates the skin to inject medicine, and at the same time that the press-fitting block opens the air discharge hole and the air in the air retention space is discharged to the outside, the press-fitting block is released and the point at which the needle portion that has penetrated the skin detaches is provided. [Means for solving the problem]

[0011] To achieve the above-described objectives of the present invention, the syringe-type microneedle according to the present invention is characterized by comprising: a housing having a hollow shape with the top and bottom open, an air discharge hole formed through its outer circumferential surface, and an air retention space formed inside that communicates with the air discharge hole; a press-fit block inserted into the air retention space of the housing and closely adhering to the inner circumferential surface of the air retention space of the housing so as to seal the air discharge hole, and opening and closing the air discharge hole so that the air in the air retention space is discharged to the outside through the air discharge hole; a needle portion placed on the bottom surface of the press-fit block and formed to contain a drug of a specified substance, exposed to the lower part of the housing by the press-fit block and penetrating into the skin; a pressurizing portion inserted and coupled into the air retention space so as to be located above the press-fit block, and pushing the air in the air retention space toward the press-fit block, guiding the press-fit block to move downward; and a protective film attached to the lower end of the housing to seal it and prevent contaminants contained in the air from penetrating the needle portion.

[0012] In the syringe-type microneedle according to the present invention, the housing is further characterized by having a stopper formed along the inner circumferential surface of the air retention space to prevent the lower end of the pressurizing portion from coming into contact with the press-fitting block.

[0013] The syringe-type microneedle according to the present invention is characterized in that the housing is formed by bending in directions opposite to each other at its lower end frame, but allows the bottom frame of the press-fit block to engage with it, thereby preventing the press-fit block from moving beyond a predetermined distance from the lower end of the housing; and an adhesive film is further formed on the bottom surface of the hanger jaw to adhere to the skin and prevent the housing from moving.

[0014] In the syringe-type microneedle according to the present invention, the housing is characterized in that the distance from the air discharge hole to the lower end of the housing is formed to be further away from the height of the press-fit block.

[0015] The syringe-type microneedle according to the present invention is characterized in that the needle portion is formed from one of the following structures: a coating type that coats its outer surface with a drug, a melting type that penetrates into the skin and melts, or a drug injection type that receives a drug inside but penetrates into the skin to deliver the drug. [Effects of the Invention]

[0016] According to the present invention, after the needle portion penetrates the skin layer through a simple action of pressing the press-fitting block against the pressurizing section, the pressure is automatically released at a predetermined time. This release of the pressure on the press-fitting block allows the practitioner to easily predict the time of needle detachment, and the guidance of the needle detachment time makes it easy for even inexperienced users to use, allowing a uniform amount of medicine to penetrate the patient and provide the same therapeutic effect to patients. In particular, after the medicine in the needle portion penetrates the skin layer, the needle portion is quickly removed, so there is no risk of the needle portion remaining in the skin layer for an excessive amount of time. This prevents skin damage or skin tissue necrosis caused by the needle portion remaining in the skin layer. Furthermore, since the needle portion penetrates the skin with the lower end of the housing adhered to the skin, there is no risk of the housing flowing on the skin surface, which has the advantage of improving the reliability of the product. [Brief explanation of the drawing]

[0017] [Figure 1] A perspective view showing a syringe-type microneedle according to the present invention. [Figure 2] Decomposed perspective view of Figure 1. [Figure 3] A cross-sectional perspective view showing the protective film separated using the syringe-type microneedle according to the present invention. [Figure 4]Cross-sectional perspective view showing a state in which a moving block is pressed downward by a pressurizing portion of a syringe-type micro needle according to the present invention. [Figure 5] Cross-sectional perspective view showing a state in which air is discharged from an air discharge hole of a syringe-type micro needle according to the present invention.

Mode for Carrying Out the Invention

[0018] Hereinafter, embodiments of the present invention will be described in more detail with reference to the accompanying drawings.

[0019] Referring to FIGS. 1 to 5, the housing (100) has a hollow shape with open upper and lower portions, forms an air discharge hole (101) penetrating through its outer peripheral surface, and forms an air retention space (102) communicating with the air discharge hole (101) inside.

[0020] The lower end of the housing (100) adheres to the skin surface corresponding to the skin layer to be penetrated by the needle portion (300).

[0021] The housing (100) is preferably formed in a cylindrical shape and receives the press-fitting block (200) and the pressurizing portion (400) inside.

[0022] The housing (100) receives air in the air retention space (102).

[0023] The housing (100) further forms a stopper (103) formed along the inner peripheral surface of the air retention space (102) to prevent the lower end of the pressurizing portion (400) from contacting the press-fitting block (200).

[0024] The stopper (103) prevents the lower end of the pressurizing portion (400) from approaching the press-fitting block (200) direction and adhering to the upper end of the press-fitting block (200) or the press-fitting block (200) from being moved upward and adhering to the lower end of the pressurizing portion (400).

[0025] The stopper (103) restricts the movement of the lower end of the pressurized portion (400), preventing the pressurized portion (400) from entering the air retention space (102) beyond a predetermined depth.

[0026] It is preferable that the stopper (103) is formed at a position relatively higher than the height of the air discharge hole (101).

[0027] The air discharge holes (101) consist of at least one and are in communication with the circulating air retention space (102) which is opened by the press-fitting block (200), and discharge the air in the air retention space (102) to the outside.

[0028] It is preferable that the above-mentioned air discharge holes (101) are formed on the same horizontal line.

[0029] The housing (100) is formed such that the distance (L) from the air discharge hole (101) to the lower end of the housing (100) is further away relative to the height (H) of the press-fit block (200).

[0030] Preferably, the air discharge hole (101) is formed at a position higher relative to the four press-fit blocks (200) that have been moved to the lower end of the housing (100).

[0031] The housing (100) is formed by bending its lower end frame in directions opposite to each other, but is provided with a hook (104) that allows the bottom frame of the press-fit block (200) to engage with it, thereby preventing the press-fit block (200) from moving beyond a predetermined distance from the lower end of the housing (100), and an adhesive film (105) is further formed on the bottom surface of the hook (104) that adheres to the skin and prevents the housing (100) from moving.

[0032] The hook jaw (104) is formed to prevent interference with the needle portion (300) exposed below the housing (100), thereby restricting the movement of the press-fit block (200).

[0033] The adhesive film (105) is formed with a double-sided tape structure, with its upper surface attached to the hook chin (104), and its bottom surface attached to the skin surface to prevent the housing (100) from sliding on the skin surface.

[0034] The adhesive film (105) adheres to the skin surface and prevents airborne contaminants from entering the housing (100) through the gap between the lower end of the housing (100) and the skin surface when the needle portion (300) penetrates the skin.

[0035] The press-fit block (200) is inserted into the air retention space (102) of the housing (100) and is tightly fitted to the inner circumferential surface of the air retention space (102) of the housing (100) so as to seal the air discharge hole (101) and opens and closes the air discharge hole (101) so that the air in the air retention space (102) is discharged to the outside through the air discharge hole (101).

[0036] The press-fit block (200) is made of an elastic rubber or silicone material and is in close contact with the inner circumferential surface of the air retention space (102).

[0037] The press-fit block (200) is pushed downward by the air pressure in the air retention space (102).

[0038] The press-fit block (200) reaches the lower end of the housing (100) and opens the air discharge hole (101) of the housing (100).

[0039] The press-fit block (200) is blocked by the stopper (103) of the housing (100), preventing it from moving upward within the air retention space (102).

[0040] It is preferable that the press-fitting block (200) is formed with the same diameter as the lower end diameter of the pressurizing portion (400).

[0041] The press-fitting block (200) is installed within the air retention space (102) to position the needle portion (300) within the housing (100).

[0042] The height (H) of the press-fit block (200) is formed to be relatively low compared to the distance (L) from the lower end of the housing (100) to the air discharge hole (101).

[0043] The needle portion (300) is placed on the bottom surface of the press-fitting block (200), is formed to contain a specified drug substance, and is exposed to the lower part of the housing (100) by the press-fitting block (200) and penetrates the skin.

[0044] Multiple needle portions (300) are formed on the bottom surface of the press-fitting block (200) so as to be spaced apart at predetermined intervals.

[0045] The needle portion (300) is pressurized by the press-in block (200) and embedded in the skin, while the drug is injected into the skin layer.

[0046] The needle portion (300) described above is formed with one of the following structures: a coating type that coats its outer surface with a drug, a melting type that penetrates into the skin and dissolves, or a drug injection type that receives a drug inside but penetrates into the skin to deliver the drug.

[0047] The pressurizing section (400) is inserted and coupled into the air retention space (102) so as to be positioned above the press-fitting block (200), and pushes the air in the air retention space (102) toward the press-fitting block (200), guiding the press-fitting block (200) to move downward.

[0048] The pressurized portion (400) is formed of a rubber or silicone material that is in close contact with the inner circumferential surface of the air retention space (102), with its lower end having elastic force.

[0049] As the pressurizing section (400) moves downward, it compresses the air in the air retention space (102) downward, forcing the press-fitting block (200) to move downward due to this compressed air.

[0050] The pressurized portion (400) has its upper end resting on the upper end of the housing (100), preventing it from entering the housing (100) beyond a predetermined distance.

[0051] The lower end of the pressurizing portion (400) is blocked by the stopper (103) of the housing (100), preventing it from coming into close contact with the upper surface of the press-fitting block (200).

[0052] The protective film (500) is attached to the lower end of the housing (100) to seal it and prevent contaminants contained in the air from penetrating the needle portion (300).

[0053] Preferably, the protective film (500) is attached to the adhesive film (105) to seal the lower end of the housing (100).

[0054] The syringe-type microneedle according to the present invention, configured as described above, is used as follows.

[0055] First, a syringe-type microneedle is provided, which has a needle portion (300) containing the substance to be injected into the patient. Then, a protective film (500) that seals the lower end of the housing (100) of the syringe-type microneedle is detached.

[0056] Here, as the protective film (500) detaches at the lower end of the housing (100), the adhesive film (105) attached to the bottom surface of the hook jaw (104) is exposed. This adhesive film (105) is then attached to the skin surface corresponding to the skin layer in which the drug is to be injected, thereby fixing the lower end of the housing (100) to the skin surface.

[0057] Next, the pressurizing portion (400) exposed above the housing (100) is pressed and pressurized to pressurize the air received in the air retention space (102) between the lower end of the pressurizing portion (400) and the press-fitting block (200) downwards.

[0058] As a result, the pressurizing part (400) slides downward within the air retention space (102) of the housing (100), compressing the air in the air retention space (102), and in that state, it continues to move downward, pushing this compressed air downward.

[0059] At this time, the air in the air retention space (102) is compressed by the pressurizing section (400), and when this pressure rises above a predetermined pressure, the press-fitting block (200) is pushed downward by the compressed air.

[0060] Here, the press-fit block (200) is fixed in the air retention space (102) with the air discharge hole (101) of the housing (100) closed, and is moved downward by the compressed air that is moved downward by the pressurizing part (400).

[0061] At this time, the pressurized portion (400) is prevented from entering the air retention space (102) of the housing (100) beyond a predetermined depth by its lower end being blocked by the stopper (103) of the housing (100), and is also prevented from coming into close contact with the press-fit block (200).

[0062] As a result, the needle portion (300) installed in the press-fitting block (200) is exposed below the housing (100) and gradually penetrates the skin layer, injecting the drug into the skin layer.

[0063] Here, the bottom frame of the press-fit block (200) engages with the hook jaw (104) of the housing (100), preventing it from detaching downward from the housing (100).

[0064] At this time, the needle portion (300) is formed in one of the following structures: a coating type that coats its outer surface with medicine, a melting type that penetrates into the skin and dissolves, or a drug injection type that receives medicine inside but penetrates into the skin to deliver the medicine, thereby injecting the medicine into the skin layer.

[0065] Next, when the press-fit block (200) is pushed by the compressed air in the air retention space (102) and moves to the lower end of the housing (100), the air discharge hole (101) opens and communicates with the air retention space (102), and at this time, the air in the air retention space (102) is discharged to the outside of the housing (100) through the air discharge hole (101).

[0066] As a result, the air in the air retention space (102) is discharged to the outside, and the compressed air that pressurizes the press-fit block (200) within the air retention space (102) gradually disappears, thereby releasing the pressurizing force on the press-fit block (200).

[0067] At the same time, the air discharge from the air retention space (102) releases the pressure input to the pressurized part (400). At this time, the practitioner senses the moment when the pressure input to the pressurized part (400) is released and detaches the housing (100) upward, thereby detaching the needle part (300) from the skin layer.

[0068] Furthermore, when the housing (100) is detached upward, the adhesive film (105) is simultaneously detached from the skin surface, preventing any residue of the adhesive film (105) from remaining on the skin surface.

[0069] Here, the point at which the pressure input to the pressurizing part (400) is released corresponds to the point at which the needle part (300) has completed injecting the drug into the skin layer.

[0070] Furthermore, the syringe-type microneedles used as described above are single-use products and are disposed of after use.

[0071] As described above, the pressurizing section (400) compresses and pushes out the air in the air retention space (102) so that the needle portion (300) formed on the press-fitting block (200) penetrates the skin. However, when the press-fitting block (200) reaches the lower end of the housing due to the compressed air, the air in the air retention space (102) is discharged to the outside through the air discharge hole (101), releasing the pressure on the press-fitting block (200). This structure allows the needle portion (300) to penetrate the skin layer through the simple action of pressing and pressurizing the press-fitting block (200) with the pressurizing section (400), and then the pressure is automatically released at a predetermined time. This release of the pressure on the press-fitting block (200) allows the practitioner to easily predict the time of detachment of the needle portion (300), and with guidance on the time of detachment of the needle portion (300), even inexperienced users can easily use the device, and a uniform amount of medicine can be penetrated into the patient, giving the patient the same therapeutic effect.

[0072] The syringe-type microneedle according to the present invention, as described above, is not limited to the embodiments described above, and does not depart from the spirit of the invention as claimed in the following claims, and its technical spirit is such that it can be modified and implemented in various ways by anyone with ordinary skill in the art to which the present invention belongs.

Claims

1. A housing (100) having a hollow shape with the top and bottom open, with an air discharge hole (101) formed through its outer circumferential surface, and an air retention space (102) formed inside that communicates with the air discharge hole (101); a press-fit block (200) inserted into the air retention space (102) of the housing (100), which is in close contact with the inner circumferential surface of the air retention space (102) of the housing (100) to seal the air discharge hole (101), and which opens and closes the air discharge hole (101) so that the air in the air retention space (102) is discharged to the outside through the air discharge hole (101); and a device placed on the bottom surface of the press-fit block (200) which is formed to contain a specified substance. A syringe-type microneedle comprising: a needle portion (300) exposed at the bottom of the housing (100) by the press-fitting block (200) and penetrating the skin; a pressurizing portion (400) inserted and coupled into the air retention space (102) so as to be located above the press-fitting block (200), which pushes the air in the air retention space (102) toward the press-fitting block (200) and guides the press-fitting block (200) to move downward; and a protective film (500) attached to the lower end of the housing (100) to seal it and prevent contaminants contained in the air from penetrating the needle portion (300); The syringe-type microneedle is characterized by the following features: the housing (100) is formed by bending in directions opposite to each other at its lower end frame, but allows the bottom frame of the press-fit block (200) to engage with the housing (100), thereby preventing the press-fit block (200) from moving beyond a predetermined distance toward the lower end of the housing (100); and an adhesive film (105) is further formed on the bottom surface of the hook (104) to adhere to the skin and prevent the housing (100) from moving.

2. The syringe-type microneedle according to claim 1, wherein the housing (100) is further formed along the inner circumferential surface of the air retention space (102) and includes a stopper (103) that prevents the lower end of the pressurizing portion (400) from coming into contact with the press-fitting block (200).

3. The syringe-type microneedle according to claim 1, characterized in that the housing (100) is formed such that the distance (L) from the air discharge hole (101) to the lower end of the housing (100) is further away relative to the height (H) of the press-fit block (200).

4. The syringe-type microneedle according to claim 1, characterized in that the needle portion (300) is formed from one of the following structures: a coating type which coats its outer surface with a drug, a melting type which penetrates into the skin and melts, or a drug injection type which receives a drug inside but penetrates into the skin to deliver the drug.

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